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https://www.readbyqxmd.com/read/28749617/depression-hopelessness-and-social-support-among-breast-cancer-patients-in-highly-endogamous-population
#1
Abdulbari Bener, Reem Alsulaiman, Lisa Doodson, Tony Agathangelou
Aim: The aim of this study was to assess the relationship between different demographic variables, hopelessness, depression and social support of Breast cancer patients in Qatari’s population. Design: This is an observational cohort hospital based study. Subjects and Methods: The study included 678 breast cancer patients. The questionnaires included a demographic questionnaire, the Beck Hopelessness Scale (BHS), Back Depression Scale (BDS) and Multidimensional Scale of Perceived Social Support (MSPSS). The demographic questionnaire was used to assess patients’ basic information including gender, age, marital status, education, family size, and place of residence...
July 27, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28749609/ricochet-pollination-in-senna-fabaceae-petals-deflect-pollen-jets-and-promote-division-of-labour-among-flower-organs
#2
Thiago Amorim, Brigitte Marazzi, Arlete A Soares, Eliana R Forni-Martins, Celli R Muniz, Christian Westerkamp
Naturalists Fritz and Hermann Müller hypothesised that heteranthery often leads to a division of labour into 'feeding' and 'pollinating' stamens; the latter often being as long as the pistil so as to promote successful pollination on the bees' back. In many buzz-pollinated species of Senna, however, the so-called pollinating stamens are short and do not level with the stigma, raising the question of how pollen is shed on the bees' back. Here we explore a mechanism called "ricochet pollination". We test whether division of labour is achieved through the interaction between short lower stamens and strongly concave "deflector petals"...
July 27, 2017: Plant Biology
https://www.readbyqxmd.com/read/28749479/communicating-prognosis-with-parents-of-critically-ill-infants-direct-observation-of-clinician-behaviors
#3
R D Boss, M E Lemmon, R M Arnold, P K Donohue
OBJECTIVE: Delivering prognostic information to families requires clinicians to forecast an infant's illness course and future. We lack robust empirical data about how prognosis is shared and how that affects clinician-family concordance regarding infant outcomes. STUDY DESIGN: Prospective audiorecording of neonatal intensive care unit family conferences, immediately followed by parent/clinician surveys. Existing qualitative analysis frameworks were applied. RESULTS: We analyzed 19 conferences...
July 27, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28749464/the-cohesin-complex-prevents-myc-induced-replication-stress
#4
Sara Rohban, Aurora Cerutti, Marco J Morelli, Fabrizio d'Adda di Fagagna, Stefano Campaner
The cohesin complex is mutated in cancer and in a number of rare syndromes collectively known as Cohesinopathies. In the latter case, cohesin deficiencies have been linked to transcriptional alterations affecting Myc and its target genes. Here, we set out to understand to what extent the role of cohesins in controlling cell cycle is dependent on Myc expression and activity. Inactivation of the cohesin complex by silencing the RAD21 subunit led to cell cycle arrest due to both transcriptional impairment of Myc target genes and alterations of replication forks, which were fewer and preferentially unidirectional...
July 27, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/28748670/whole-genome-detection-of-signature-of-positive-selection-in-african-cattle-reveals-selection-for-thermotolerance
#5
Mengistie Taye, Wonseok Lee, Kelsey Caetano-Anolles, Tadelle Dessie, Olivier Hanotte, Okeyo Ally Mwai, Stephen Kemp, Seoae Cho, Sung Jong Oh, Hak-Kyo Lee, Heebal Kim
As African indigenous cattle evolved in a hot tropical climate, they have developed an inherent thermotolerance; survival mechanisms include a light-colored and shiny coat, increased sweating, and cellular and molecular mechanisms to cope with high environmental temperature. Here, we report the positive selection signature of genes in African cattle breeds which contribute for their heat tolerance mechanisms. We compared the genomes of five indigenous African cattle breeds with the genomes of four commercial cattle breeds using cross-population composite likelihood ratio (XP-CLR) and cross-population extended haplotype homozygosity (XP-EHH) statistical methods...
July 27, 2017: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/28748655/high-throughput-automated-microbial-bioreactor-system-used-for-clone-selection-and-rapid-scale-down-process-optimisation
#6
M Lourdes Velez-Suberbie, John Pj Betts, Kelly L Walker, Colin Robinson, Barney Zoro, Eli Keshavarz-Moore
High throughput automated fermentation systems have become a useful tool in early bioprocess development. In this study, we investigated a 24 x 15 mL single use microbioreactor system, ambr 15f, designed for microbial culture. We compared the fed-batch growth and production capabilities of this system for two Escherichia coli strains, BL21 (DE3) and MC4100, and two industrially relevant molecules, hGH and scFv. In addition, different carbon sources were tested using bolus, linear or exponential feeding strategies, showing the capacity of the ambr 15f system to handle automated feeding...
July 27, 2017: Biotechnology Progress
https://www.readbyqxmd.com/read/28748632/first-molecular-identification-of-the-vertebrate-hosts-of-culicoides-imicola-in-europe-and-a-review-of-its-blood-feeding-patterns-worldwide-implications-for-the-transmission-of-bluetongue-disease-and-african-horse-sickness
#7
J Martínez-DE LA Puente, J Navarro, M Ferraguti, R Soriguer, J Figuerola
Culicoides (Diptera: Ceratopogonidae) are vectors of pathogens that affect wildlife, livestock and, occasionally, humans. Culicoides imicola (Kieffer, 1913) is considered to be the main vector of the pathogens that cause bluetongue disease (BT) and African horse sickness (AHS) in southern Europe. The study of blood-feeding patterns in Culicoides is an essential step towards understanding the epidemiology of these pathogens. Molecular tools that increase the accuracy and sensitivity of traditional methods have been developed to identify the hosts of potential insect vectors...
July 27, 2017: Medical and Veterinary Entomology
https://www.readbyqxmd.com/read/28748574/delayed-postoperative-diet-is-associated-with-a-greater-incidence-of-prolonged-postoperative-ileus-and-longer-stay-in-hospital-for-patients-undergoing-gastrointestinal-surgery
#8
Joanna Rees, Kelly Bobridge, Catherine Cash, Philippa Lyons-Wall, Rebecca Allan, Jacqui Coombes
AIM: Recent evidence favours a move away from delaying postoperative nutrition towards early feeding practices for better patient outcomes after gastrointestinal surgery. The aim of the present study was to investigate postoperative diet progression and patient outcomes in a secondary hospital with a view to inform future practice. METHODS: This was a retrospective study of gastrointestinal surgery patients (n = 69) at a Western Australian general hospital. Demographic data and outcomes were collected from patient records and included presence or absence of prolonged postoperative ileus, length of stay in hospital, days on minimal nutrition and days until first flatus or stool...
July 26, 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28748451/the-emerging-role-and-targetability-of-the-tca-cycle-in-cancer-metabolism
#9
REVIEW
Nicole M Anderson, Patrick Mucka, Joseph G Kern, Hui Feng
The tricarboxylic acid (TCA) cycle is a central route for oxidative phosphorylation in cells, and fulfills their bioenergetic, biosynthetic, and redox balance requirements. Despite early dogma that cancer cells bypass the TCA cycle and primarily utilize aerobic glycolysis, emerging evidence demonstrates that certain cancer cells, especially those with deregulated oncogene and tumor suppressor expression, rely heavily on the TCA cycle for energy production and macromolecule synthesis. As the field progresses, the importance of aberrant TCA cycle function in tumorigenesis and the potentials of applying small molecule inhibitors to perturb the enhanced cycle function for cancer treatment start to evolve...
July 26, 2017: Protein & Cell
https://www.readbyqxmd.com/read/28748430/inicu-integrated-neonatal-care-unit-capturing-neonatal-journey-in-an-intelligent-data-way
#10
Harpreet Singh, Gautam Yadav, Raghuram Mallaiah, Preetha Joshi, Vinay Joshi, Ravneet Kaur, Suneyna Bansal, Samir K Brahmachari
Neonatal period represents first 28 days of life, which is the most vulnerable time for a child's survival especially for the preterm babies. High neonatal mortality is a prominent and persistent problem across the globe. Non-availability of trained staff and infrastructure are the major recognized hurdles in the quality care of these neonates. Hourly progress growth charts and reports are still maintained manually by nurses along with continuous calculation of drug dosage and nutrition as per the changing weight of the baby...
August 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28748329/impact-of-thiamethoxam-on-honey-bee-queen-apis-mellifera-carnica-reproductive-morphology-and-physiology
#11
Ivana Tlak Gajger, Martina Sakač, Aleš Gregorc
High honey bee losses around the world have been linked in part by the regular use of neonicotinoids in agriculture. In light of the current situation, the aim of this study was to investigate the effects of thiamethoxam on the development of the reproductive system and physiology in the honey bee queen. Two experimental groups of honey bee queen larvae were treated with thiamethoxam during artificial rearing, applied via artificial feed in two cycles. In the first rearing cycle, honey bee larvae received a single treatment dose (4...
July 26, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28748304/the-eye-fluke-tylodelphys-clavata-affects-prey-detection-and-intraspecific-competition-of-european-perch-perca-fluviatilis
#12
Jenny Carolina Vivas Muñoz, Georg Staaks, Klaus Knopf
Parasites that occupy the eyes of fish have the potential to affect visual perception and consequently alter the host's behaviour, as these organs provide information about their surroundings. In an experimental study, the feeding behaviour of European perch (Perca fluviatilis) infested with the eye fluke Tylodelphys clavata was examined. The results showed that an individual's ability to identify and approach food items was negatively affected by the infestation intensity of T. clavata. Additionally, the foraging success of an individual was reduced in competition with another, less heavily infested conspecific, when the same food resource was exploited...
July 27, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28748301/the-aflatoxin-detoxifizyme-specific-expression-in-the-parotid-gland-of-transgenic-pigs
#13
An-Gang Lou, Jin-Shun Cai, Xue-Mei Zhang, Cheng-Dou Cui, Ying-Shu Piao, Li-Zeng Guan
Producing aflatoxin-detoxifizyme (ADTZ) in pigs to control the AFT contamination of pig feed is a new research strategy by transgenic technology. In this study, transgenic pigs specifically expressing ADTZ gene in the parotid gland were successfully produced by somatic cell nuclear transfer technology. The ADTZ activity in saliva of 6 transgenic pigs was found to be 7.11 ± 2.63 U/mL. The feeding trial with aflatoxin (AFT) results showed that there were significant difference about the serum biochemical index such as total protein (TP), albumin (ALB), globulin (GLB) contents and alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activity and AFT residues in serum and liver between the pigs in the test treatment (transgenic pigs) producing ADTZ and those in the positive control (P < 0...
July 26, 2017: Transgenic Research
https://www.readbyqxmd.com/read/28748260/clinical-predictors-for-reactive-tube-feeding-in-patients-with-advanced-oropharynx-cancer-receiving-radiotherapy%C3%A2-%C3%A2-%C3%A2-chemotherapy
#14
Belinda Vangelov, Robert I Smee
Enteral feeding is often required for nutrition support in head and neck cancer patients when oral intake is inadequate. When to initiate the insertion of a feeding tube continues to be a debated issue in our institution. We investigated the use of reactive feeding tubes (RFTs) in patients with advanced stage oropharynx cancer (OPC). Data were retrospectively collected on 131 patients who had radiotherapy (RT) ± chemotherapy from 2005 to 2015. Predictors for RFT insertion were investigated. Weight loss during RT was compared between those with RFT versus prophylactic tubes (PFTs) versus no tube, and survival outcomes evaluated...
July 26, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28748130/isolation-and-identification-of-bifidobacterium-species-from-feces-of-captive-chimpanzees
#15
Ryohei Nomoto, Shintaro Takano, Kosei Tanaka, Yuji Tsujikawa, Hiroshi Kusunoki, Ro Osawa
Recently, gut-dwelling bifidobacteria from chimpanzees, which are phylogenetically close to humans and have feeding habits similar to humans, have been frequently investigated. Given this, we speculated that like humans, chimpanzees would have a unique diversity of bifidobacteria. We herein describe a taxonomically novel member of bifidobacteria isolated from fecal samples of captive chimpanzees. Bifidobacteria were detected in all fecal samples by quantitative polymerase chain reaction. A Bifidobacterium pseudolongum-like species, which could not be detected using B...
2017: Bioscience of Microbiota, Food and Health
https://www.readbyqxmd.com/read/28748079/oxidative-stability-of-chilled-broiler-breast-meat-as-affected-by%C3%A2-dietary-supplementation-with-rosemary-rosmarinus-officinalis-l-powder-and-vitamin-e
#16
Hossein Rostami, Alireza Seidavi, Mohammad Dadashbeiki, Yadollah Asadpour, João Simões, Vito Laudadio, Chrysostomos Milis, Vincenzo Tufarelli
The aim of the present study was to evaluate the effect of rosemary (Rosmarinus officinalis L.) powder and vitamin E, as feed additives combined at different levels, on oxidative stability of broiler meat up to 14th day after chilling. A total of 270 1-day-old male chicks of Ross 308 strain were randomly assigned to nine dietary groups with three replicates having 10 birds each. Diets were supplemented with 0, 0.5, or 1.0% of rosemary (R) powder and 0, 100, or 200 mg/kg of vitamin E (alpha-tocopherol acetate; VitE) according to the following treatments: T1 - control basal diet (0R + 0VitE); T2 - 0R + 100VitE; T3 - 0R + 200VitE; T4 - 0...
July 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28747934/avoidant-restrictive-food-intake-disorder-in-an-11-year-old-south-american-boy-medical-and-cultural-challenges
#17
Jonah Schermbrucker, Melissa Kimber, Natasha Johnson, Sarah Kearney, Jennifer Couturier
Avoidant/Restrictive Food Intake Disorder (ARFID) is new in the DSM-5, replacing the DSM-IV-TR diagnosis of Feeding Disorder of Infancy or Early Childhood. ARFID has no age criterion, and therefore addresses eating disturbances across the lifespan. This report illustrates the case of an 11-year-old boy of Colombian ancestry with ARFID and explores the role of culture in the diagnosis of ARFID. To date, literature describing this disorder is limited. ARFID is often seen in the child and adolescent population and can have significant medical consequences, including weight loss, hemodynamic instability, and growth retardation...
July 2017: Journal of the Canadian Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28747887/nutrient-sensing-another-chemosensitivity-of-the-olfactory-system
#18
REVIEW
A-Karyn Julliard, Dolly Al Koborssy, Debra A Fadool, Brigitte Palouzier-Paulignan
Olfaction is a major sensory modality involved in real time perception of the chemical composition of the external environment. Olfaction favors anticipation and rapid adaptation of behavioral responses necessary for animal survival. Furthermore, recent studies have demonstrated that there is a direct action of metabolic peptides on the olfactory network. Orexigenic peptides such as ghrelin and orexin increase olfactory sensitivity, which in turn, is decreased by anorexigenic hormones such as insulin and leptin...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28747726/association-of-micrornas-with-argonaute-proteins-in-the-malaria-mosquito-anopheles-gambiae-after-blood-ingestion
#19
Xiaonan Fu, George Dimopoulos, Jinsong Zhu
Drastic changes in gene expression occur after adult female mosquitoes take a blood meal and use the nutrients for egg maturation. A growing body of evidence indicates that microRNAs (miRNAs) contribute to this tightly controlled tissue- and stage-specific gene expression. To investigate the role of miRNAs, we monitored miRNA expression in the mosquito Anopheles gambiae during the 72-h period immediately after blood feeding. We also measured the association of miRNAs with Argonaute 1 (Ago1) and Argonaute 2 (Ago2) to assess the functional status of individual miRNA species...
July 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28747694/decreasing-parental-task-specialization-promotes-conditional-cooperation
#20
Arne Iserbyt, Nolwenn Fresneau, Tiffanie Kortenhoff, Marcel Eens, Wendt Müller
How much to invest in parental care and by who remain puzzling questions fomented by a sexual conflict between parents. Negotiation that facilitates coordinated parental behaviour may be key to ease this costly conflict. However, understanding cooperation requires that the temporal and sex-specific variation in parental care, as well as its multivariate nature is considered. Using a biparental bird species and repeated sampling of behavioural activities throughout a major part of reproduction, we show a clear division of tasks between males and females in provisioning, brooding and foraging...
July 26, 2017: Scientific Reports
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