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Candida colonization

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https://www.readbyqxmd.com/read/28213809/the-correlation-between-biofilm-production-and-catheter-related-blood-stream-infections-sustained-by-candida-a-case-control-study
#1
Grazia Brunetti, Valeria Visconti, Maria Cristina Ghezzi, Alessandra Giordano, Giammarco Raponi
Biofilm forming capacity of yeasts colonizing the intravenous devices is considered a key factor involved in the pathogenesis of Candida catheter-related bloodstream infections (CCRBSI). The biofilm production of strains of Candida spp. isolated both from the CVC and from the blood of patients with CCRBSI was compared to that of strains isolated from patients not having CCRBSI. Results, expressed in terms of Biofilm Index (BI), revealed that biofilm-producing strains were isolated in the CCRBSI group with a frequency significantly higher than in the non-CCRBSI group (χ(2) = 4...
February 18, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28203228/encapsulation-of-antifungals-in-micelles-protects-candida-albicans-during-gall-bladder-infection
#2
Shih-Hung Hsieh, Sascha Brunke, Matthias Brock
Candida albicans is a dimorphic fungus that colonizes human mucosal surfaces with the potential to cause life-threatening invasive candidiasis. Studies on systemic candidiasis in a murine infection model using in vivo real-time bioluminescence imaging revealed persistence of C. albicans in the gall bladder under antifungal therapy. Preliminary analyses showed that bile conferred resistance against a wide variety of antifungals enabling survival in this cryptic host niche. Here, bile and its components were studied for their ability to reduce antifungal efficacy in order to elucidate the underlying mechanism of protection...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28184328/frequency-of-candidiasis-and-colonization-of-candida-albicans-in-relation-to-oral-contraceptive-pills
#3
Atousa Aminzadeh, Ali Sabeti Sanat, Saeed Nik Akhtar
BACKGROUND: Candidiasis, the infection caused by Candida albicans, is one of the most common infections of the oral cavity in humans. Candidiasis causes irritation and is known for its carcinogenic effects. Thus, it is important to recognize the predisposing factors for this opportunistic infection. Several previous studies have demonstrated an increased frequency of vaginal candidiasis in relation to oral contraceptive consumption. OBJECTIVES: Only a few studies on the relation between oral contraceptives and oral candidiasis have been previously conducted...
October 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/28150479/the-intestinal-mycobiota-a-year-of-observation-about-the-incidence-of-yeast-s-isolation-in-fecal-samples
#4
Lucia Barcella, Santa B Rogolino, Angelo P Barbaro
BACKGROUND: Yeast's presence, especially Candida's species, in the intestinal tract is now considered as part of the normal microbial human flora; however, fungal colonization of the colon may induce to fungal infections, becoming a risk not only in immunocompromised patients but also in normalcompetent subjects. The purpose of this epidemiological study was to evaluate the real incidence of yeasts into the fecal samples both from healthy outpatients and from inpatients, except those from wards concerning immunosuppressive and pediatrics pathologies...
February 1, 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28148273/prevalence-of-candida-albicans-and-non-albicans-on-the-tongue-dorsa-of-elderly-people-living-in-a-post-disaster-area-a-cross-sectional-survey
#5
Toshiro Sato, Mitsuo Kishi, Miki Suda, Kiyomi Sakata, Haruki Shimoda, Hiroyuki Miura, Akira Ogawa, Seiichiro Kobayashi
BACKGROUND: Candida species are normal commensal organisms of the mouth. However, they can cause oral mucosal and severe systemic infections in persons with reduced immune function, which is common in the very elderly. In post-disaster areas, the number of elderly residents rapidly increases due to the outflow of younger generations. Hence, we examined the prevalence of Candida albicans and non-albicans in association with oral and systemic conditions, life style, medications, and living conditions...
February 1, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28139480/evaluation-of-role-of-fixed-orthodontics-in-changing-oral-ecological-flora-of-opportunistic-microbes-in-children-and-adolescent
#6
Chandresh Shukla, Rajkumar Maurya, Vinod Singh, Manisha Tijare
OBJECTIVE: To determine the prevalence and counts of Streptococcus mutans and Candida species in orthodontic fixed appliance therapy patients and comparison of the efficiency of manual and electronic toothbrushes on minimizing plaque by reducing S. mutans and Candida species in above-mentioned patients. MATERIALS AND METHODS: The study was carried out on total number of sixty patients scheduled for orthodontic treatment (age group: 13-18). Plaque samples were collected to determine oral carriage of S...
January 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28124220/in-vitro-antifungal-susceptibility-of-oral-candida-isolates-from-patients-suffering-from-caries-and-chronic-periodontitis
#7
Janire De-la-Torre, María Esther Ortiz-Samperio, Cristina Marcos-Arias, Xabier Marichalar-Mendia, Elena Eraso, María Ángeles Echebarria-Goicouria, José Manuel Aguirre-Urizar, Guillermo Quindós
Caries and chronic periodontitis are common oral diseases where a higher Candida colonization is reported. Antifungal agents could be adjuvant drugs for the therapy of both clinical conditions. The aim of the current study has been to evaluate the in vitro activities of conventional and new antifungal drugs against oral Candida isolates from patients suffering from caries and/or chronic periodontitis. In vitro activities of amphotericin B, fluconazole, itraconazole, miconazole, nystatin, posaconazole and voriconazole against 126 oral Candida isolates (75 Candida albicans, 18 Candida parapsilosis, 11 Candida dubliniensis, six Candida guilliermondii, five Candida lipolytica, five Candida glabrata, four Candida tropicalis and two Candida krusei) from 61 patients were tested by the CLSI M27-A3 method...
January 25, 2017: Mycopathologia
https://www.readbyqxmd.com/read/28120191/candida-krusei-isolated-from-fruit-juices-ultrafiltration-membranes-promotes-colonization-of-escherichia-coli-o157-h7-and-salmonella-enterica-on-stainless-steel-surfaces
#8
María Clara Tarifa, Jorge Enrique Lozano, Lorena Inés Brugnoni
To clarify the interactions between a common food spoilage yeast and two pathogenic bacteria involved in outbreaks associated with fruit juices, the present paper studies the effect of the interplay of Candida krusei, collected from UF membranes, with Escherichia coli O157:H7 and Salmonella enterica in the overall process of adhesion and colonization of abiotic surfaces. Two different cases were tested: a) co-adhesion by pathogenic bacteria and yeasts, and b) incorporation of bacteria to pre-adhered C. krusei cells...
February 2017: Journal of Microbiology / the Microbiological Society of Korea
https://www.readbyqxmd.com/read/28115357/synthesis-antifungal-activity-and-biocompatibility-of-novel-dabco-compounds-and-dabco-containing-denture-base-resins
#9
Jenny L Herman, Yapin Wang, Elizabeth Lilly, Thomas Lallier, Suleiman Hamdan, Xiaoming Xu, Paul L Fidel, Mairi C Noverr
The fungal pathogen Candida albicans causes a variety of oral infections including denture stomatitis, which is characterized by inflammation of the oral mucosa in direct contact with dentures, and affects a significant number of otherwise healthy denture wearers. While antifungal treatment reduces symptoms, infections are often recurrent. One strategy to address this problem is to incorporate compounds with fungicidal activities into denture materials to prevent colonization. Our laboratory synthesized novel derivatives of DABCO (1,4-diazabicyclo[2...
January 23, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28114348/polymicrobial-ventilator-associated-pneumonia-fighting-in-vitro-candida-albicans-pseudomonas-aeruginosa-biofilms-with-antifungal-antibacterial-combination-therapy
#10
Maria E Rodrigues, Susana P Lopes, Cláudia R Pereira, Nuno F Azevedo, Anália Lourenço, Mariana Henriques, Maria O Pereira
The polymicrobial nature of ventilator-associated pneumonia (VAP) is now evident, with mixed bacterial-fungal biofilms colonizing the VAP endotracheal tube (ETT) surface. The microbial interplay within this infection may contribute for enhanced pathogenesis and exert impact towards antimicrobial therapy. Consequently, the high mortality/morbidity rates associated to VAP and the worldwide increase in antibiotic resistance has promoted the search for novel therapeutic strategies to fight VAP polymicrobial infections...
2017: PloS One
https://www.readbyqxmd.com/read/28098529/multidrug-resistant-candida-haemulonii-and-c-auris-tel-aviv-israel
#11
Ronen Ben-Ami, Judith Berman, Ana Novikov, Edna Bash, Yael Shachor-Meyouhas, Shiri Zakin, Yasmin Maor, Jalal Tarabia, Vered Schechner, Amos Adler, Talya Finn
Candida auris and C. haemulonii are closely related, multidrug-resistant emerging fungal pathogens that are not readily distinguishable with phenotypic assays. We studied C. auris and C. haemulonii clinical isolates from 2 hospitals in central Israel. C. auris was isolated in 5 patients with nosocomial bloodstream infection, and C. haemulonii was found as a colonizer of leg wounds at a peripheral vascular disease clinic. Liberal use of topical miconazole and close contact among patients were implicated in C...
February 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28076372/bad-to-the-bone-on-in-vitro-and-ex-vivo-microbial-biofilm-ability-to-directly-destroy-colonized-bone-surfaces-without-participation-of-host-immunity-or-osteoclastogenesis
#12
Adam Junka, Patrycja Szymczyk, Grzegorz Ziółkowski, Ewa Karuga-Kuzniewska, Danuta Smutnicka, Iwona Bil-Lula, Marzenna Bartoszewicz, Susan Mahabady, Parish Paymon Sedghizadeh
Bone infections are a significant public health burden associated with morbidity and mortality in patients. Microbial biofilm pathogens are the causative agents in chronic osteomyelitis. Research on the pathogenesis of osteomyelitis has focused on indirect bone destruction by host immune cells and cytokines secondary to microbial insult. Direct bone resorption by biofilm pathogens has not yet been seriously considered. In this study, common osteomyelitis pathogens (Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans, and Streptococcus mutans) were grown as biofilms in multiple in vitro and ex vivo experiments to analyze quantitative and qualitative aspects of bone destruction during infection...
2017: PloS One
https://www.readbyqxmd.com/read/28068844/hierarchical-cluster-analysis-and-chemical-characterisation-of-myrtus-communis-l-essential-oil-from-yemen-region-and-its-antimicrobial-antioxidant-and-anti-colorectal-adenocarcinoma-properties
#13
Sirajudheen Anwar, Rebecca A Crouch, Nasser A Awadh Ali, Mohamed A Al-Fatimi, William N Setzer, Ludger Wessjohann
The hydrodistilled essential oil obtained from the dried leaves of Myrtus communis, collected in Yemen, was analysed by GC-MS. Forty-one compounds were identified, representing 96.3% of the total oil. The major constituents of essential oil were oxygenated monoterpenoids (87.1%), linalool (29.1%), 1,8-cineole (18.4%), α-terpineol (10.8%), geraniol (7.3%) and linalyl acetate (7.4%). The essential oil was assessed for its antimicrobial activity using a disc diffusion assay and resulted in moderate to potent antibacterial and antifungal activities targeting mainly Bacillus subtilis, Staphylococcus aureus and Candida albicans...
January 9, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28068390/effect-of-inulin-on-proteome-changes-induced-by-pathogenic-lipopolysaccharide-in-human-colon
#14
Michele Pier Luca Guarino, Annamaria Altomare, Simone Barera, Vittoria Locato, Silvia Cocca, Cinzia Franchin, Giorgio Arrigoni, Candida Vannini, Sarah Grossi, Paola Campomenosi, Valentina Pasqualetti, Marcella Bracale, Rossana Alloni, Laura De Gara, Michele Cicala
In the present study, the protective role of inulin against lipopolysaccharide (LPS)-induced oxidative stress was evaluated on human colonic mucosa using a proteomic approach. Human colonic mucosa and submucosa were sealed between two chambers, with the luminal side facing upwards and overlaid with Krebs (control), LPS or LPS+ inulin IQ solution. The solutions on the submucosal side (undernatants) were collected following 30 min of mucosal exposure. iTRAQ based analysis was used to analyze the total soluble proteomes from human colonic mucosa and submucosa treated with different undernatants...
2017: PloS One
https://www.readbyqxmd.com/read/28066812/the-denture-associated-oral-microbiome-in-health-and-stomatitis
#15
Baochen Shi, Tingxi Wu, Jeffrey McLean, Anna Edlund, Youngik Young, Xuesong He, Hongyang Lv, Xuedong Zhou, Wenyuan Shi, Huiying Li, Renate Lux
While investigation of the microbiome on natural oral surfaces has generated a wealth of information, few studies have examined the microbial communities colonizing dentures and their relationship to oral health. To address this knowledge gap, we characterized the bacterial community associated with dentures and remaining teeth in healthy individuals and patients with denture stomatitis. The microbiome compositions of matched denture and tooth plaque samples of 10 healthy individuals and 9 stomatitis patients were determined by 16S rRNA gene pyrosequencing...
November 2016: MSphere
https://www.readbyqxmd.com/read/28058136/appropriate-treatment-of-invasive-candidiasis-in-icu-timing-colonization-index-candida-score-biomarkers-towards-de-escalation
#16
Francesco Giuseppe De Rosa, Silvia Corcione, Giorgia Montrucchio, Luca Brazzi, Giovanni Di Perri
No abstract text is available yet for this article.
December 2016: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/28018842/c-dubliniensis-in-an-immunocompetent-patient-with-metal-lingual-frenulum-piercing
#17
Gary Ventolini, Peihsuan Tsai, Lee David Moore
Candida spp. are opportunistic unicellular fungi, known to cause oral, vaginal, lung and occasionally systemic infections. Characteristically, they colonize the oral cavity, the mucosal surfaces of the cheek, palate, and tongue. Usually harmless, oral Candidas may become pathogenic under immunosuppressive conditions, dentures presence, or salivary flow impairment. Accurate species identification is important because C. dubliniensis can rapidly develop fluconazole resistance. We report C. dubliniensis in an immunocompetent patient with a metal lingual frenulum piercing...
December 2016: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/27999492/evaluation-of-denture-related-factors-predisposing-to-denture-stomatitis-in-a-lebanese-population
#18
Georges Aoun, Antoine Cassia
BACKGROUND: Denture stomatitis is a common fungal oral infection of multifactorial etiology. Denture-related factors such as denture's age, hygiene, night wearing and colonization by Candida albicans are known to predispose to denture stomatitis. The aim of this study was to evaluate these factors and their relationship with the occurrence of denture stomatitis in a Lebanese population. MATERIAL AND METHODS: Sixty patients (40 women, 20 men; age range 40-80 years) showing clinical evidence of denture-related stomatitis were selected for this study...
October 2016: Materia Socio-medica
https://www.readbyqxmd.com/read/27996940/allergic-fungal-airway-disease
#19
REVIEW
E M Rick, K Woolnough, C H Pashley, A J Wardlaw
Fungi are ubiquitous and form their own kingdom. Up to 80 genera of fungi have been linked to type I allergic disease, and yet, commercial reagents to test for sensitization are available for relatively few species. In terms of asthma, it is important to distinguish between species unable to grow at body temperature and those that can (thermotolerant) and thereby have the potential to colonize the respiratory tract. The former, which include the commonly studied Alternaria and Cladosporium genera, can act as aeroallergens whose clinical effects are predictably related to exposure levels...
2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27989711/oral-health-status-in-patients-with-acquired-brain-injury-a-systematic-review
#20
REVIEW
Mohit Kothari, Rajath Sasidharan Pillai, Simple Futarmal Kothari, Rubens Spin-Neto, Abhishek Kumar, Jørgen Feldbæk Nielsen
OBJECTIVE: To undertake a systematic review of the current knowledge and future perspectives regarding the status of various oral health factors, including social and behavioral aspects, in patients with acquired brain injury (ABI). STUDY DESIGN: A structured search strategy was applied to PubMed, Embase, and Scopus electronic databases until January 2016 to identify studies presenting assessments of the oral health status of patients afflicted with any kind of ABI...
February 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
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