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anisakis simplex

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https://www.readbyqxmd.com/read/29368038/green-drugs-in-the-fight-against-anisakis-simplex-larvicidal-activity-and-acetylcholinesterase-inhibition-of-origanum-compactum-essential-oil
#1
Víctor López, María Cascella, Giovanni Benelli, Filippo Maggi, Carlota Gómez-Rincón
Anisakiasis is a fish-borne parasitic disease caused by the consumption of raw or undercooked fish, as well as cephalopods, contaminated by third instar larvae (L3) of species belonging to the genus Anisakis (Anisakidae). Origanum compactum is a small herbaceous aromatic plant endemic to Spain and Morocco. In Morocco, the plant is used under infusion to treat heart diseases and intestinal pains or as preservative for foodstuffs. This is the first time that the O. compactum essential oil is tested against the parasitic nematode Anisakis simplex...
January 24, 2018: Parasitology Research
https://www.readbyqxmd.com/read/29351069/metazoan-parasite-fauna-of-migrating-common-garfish-belone-belone-l-in-the-baltic-sea
#2
Patrick Unger, Kilian Neubert, Harry W Palm
A total of 35 common garfish, Belone belone (Linnaeus, 1761), were studied for metazoan parasites on their spawning grounds in the western Baltic Sea. Nine parasite species were found, and six new locality records could be established for German coastal waters (Axine belones, Monogenea; Proteocephalus sp., Cestoda; Anisakis simplex (s.s.), Contracaecum rudolphii A and Hysterothylacium aduncum, Nematoda; Echinorhynchus gadi, Acanthocephala). For the first time, the marine ectoparasite A. belones was recorded from the gills of garfish inside the Baltic Sea, indicating its ability to survive the spawning migration as well as the brackish water conditions at its reproduction grounds...
March 26, 2018: Acta Parasitologica
https://www.readbyqxmd.com/read/29321072/tissue-specific-transcriptomes-of-anisakis-simplex-sensu-stricto-and-anisakis-pegreffii-reveal-potential-molecular-mechanisms-involved-in-pathogenicity
#3
Serena Cavallero, Fabrizio Lombardo, Xiaopei Su, Marco Salvemini, Cinzia Cantacessi, Stefano D'Amelio
BACKGROUND: Larval stages of the sibling species of parasitic nematodes Anisakis simplex (sensu stricto) (s.s.) (AS) and Anisakis pegreffii (AP) are responsible for a fish-borne zoonosis, known as anisakiasis, that humans aquire via the ingestion of raw or undercooked infected fish or fish-based products. These two species differ in geographical distribution, genetic background and peculiar traits involved in pathogenicity. However, thus far little is known of key molecules potentially involved in host-parasite interactions...
January 10, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29306733/anisakis-spp-larvae-in-different-kinds-of-ready-to-eat-products-made-of-anchovies-engraulis-encrasicolus-sold-in-italian-supermarkets
#4
L Guardone, D Nucera, L B Lodola, L Tinacci, P L Acutis, A Guidi, A Armani
In this study the occurrence of visible anisakid larvae in semi-preserved anchovy products sold on the Italian market was investigated. Totally, 107 ready to eat products (33 salted-ripened, 49 in oil and 25 marinated) were sampled. Each sample was digested, then the digested material was observed under natural and UV light. Parasites were counted, collected and microscopically identified to genus level. A representative subset was molecularly identified using the cox2 gene. At least one visible Anisakis sp...
January 4, 2018: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/29249135/prevalence-molecular-characterization-and-clinical-relevance-of-sensitization-to-anisakis-simplex-in-children-with-sensitization-and-or-allergy-to-dermatophagoides-pteronyssinus
#5
M C Verga, R Pastorino, A Casani, F Inturrisi, C de Waure, A Pugliese, I Dello Iacono
Prevalence of the Anisakis Simplex's (AS) sensitization in children sensitized to Dermatophagoides pteronissynus (DP) is not known, neither it is to which percentage it might be due to cross-reactivity. The primary objective of the present retrospective cross-sectional study is to evaluate the prevalence of sensitization to AS in children sensitized or allergic to DP. Secondary outcomes were the prevalence of cross-reactivity and clinical relevance of the condition. The prevalence of sensitization to AS differs significantly among patients sensitized and not to DP (13...
November 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29189183/ige-sensitization-to-anisakis-simplex-and-diet-recommendation-in-a-polycentric-study
#6
Rosalba Buquicchio, Maria Teresa Ventura, Pier Luigi Traetta, Saverio Nenna, Giuseppe Iadarola, Thea Magrone
BACKGROUND: Allergy to Anisakis simplex (s.) is spreading due to the increased consumption of raw, smoked or marinated fish. In humans, Anisakis s. can directly attack the gastrointestinal mucosa, provoking a parasitosis known as anisakiasis, or giving rise to the formation of IgE and, finally, inducing IgE-mediated reactions like urticaria, angioedema and anaphylactic shock. During recent years, a dietary approach to Anisakis s. infestation has also been addressed. METHODS: A total of 620 patients with urticaria, angioedema, or both and a history of anaphylaxis following consumption of raw, smoked or marinated fish were recruited, evaluated for specific IgE levels to Anisakis s...
November 29, 2017: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/29170085/the-modelling-studies-determing-the-mode-of-action-of-anthelmintics-inhibiting-in-vitro-tpp-of-anisakis-simplex-s-l
#7
Elżbieta Łopieńska-Biernat, Tomasz Molcan, Łukasz Paukszto, Jan Paweł Jastrzębski, Kamil Myszczyński
The trehalose-6-phosphate phosphatase (TPP) enzyme is involved in the synthesis of trehalose, the main sugar in the energy metabolism of nematodes. TPP is a member of the HAD-like hydrolase superfamily and shows a robust and specific phosphatase activity for the substrate trehalose-6-phosphate. The presence of conserved active sites of TPP in closely related nematodes and its absence in humans makes it a promising target for antiparasitic drugs. In the present study, homology modeling, molecular docking and MD simulation techniques were used to explore the structure and dynamics of TPP...
November 20, 2017: Experimental Parasitology
https://www.readbyqxmd.com/read/29118653/a-combined-human-case-of-dirofilaria-ursi-infection-in-dorsal-subcutaneous-tissue-and-anisakis-simplex-sensu-stricto-s-s-infection-in-ventral-subcutaneous-tissue
#8
Minoru Yamada, Namiko Shishito, Yoshihiro Nozawa, Shigehiko Uni, Keisuke Nishioka, Takaaki Nakaya
Background: Dirofilaria ursi is a filarial nematode that parasitizes the subcutaneous tissues of the American black bear (Ursus americanus) and Japanese black bear (Ursus thiabetanus japonicus). D. ursi that has parasitized black bears has the potential to subsequently infect humans. In addition, extra-gastrointestinal anisakiasis is less common in Japan. Case presentation: We report a case of ventral subcutaneous anisakiasis and dorsal subcutaneous dirofilariasis that was acquired in Fukushima, in the northern part of Japan...
2017: Tropical Medicine and Health
https://www.readbyqxmd.com/read/28882665/human-gastric-hyperinfection-by-anisakis-simplex-a-severe-and-unusual-presentation-and-a-brief-review
#9
Teresa Baptista-Fernandes, Manuel Rodrigues, Isabel Castro, Paulo Paixão, Pedro Pinto-Marques, Lidia Roque, Silvana Belo, Pedro Manuel Ferreira, Kamal Mansinho, Cristina Toscano
Anisakiasis is an emerging marine food-borne zoonosis resulting from the accidental ingestion of Anisakis larvae, through the consumption of raw or undercooked infected seafood products. The first case of human gastric hyperinfection by Anisakis simplex with an unusual and severe presentation, occurring in a Portuguese woman, is described in this article. Over 140 anisakid larvae were removed by gastroscopy. Massive infection is uncommon in areas where the consumption of raw fish is not part of the traditional diet, as is the case in Portugal...
September 4, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28645306/excretory-secretory-products-of-anisakid-nematodes-biological-and-pathological-roles
#10
REVIEW
Foojan Mehrdana, Kurt Buchmann
Parasites from the family Anisakidae are widely distributed in marine fish populations worldwide and mainly nematodes of the three genera Anisakis, Pseudoterranova and Contracaecum have attracted attention due to their pathogenicity in humans. Their life cycles include invertebrates and fish as intermediate or transport hosts and mammals or birds as final hosts. Human consumption of raw or underprocessed seafood containing third stage larvae of anisakid parasites may elicit a gastrointestinal disease (anisakidosis) and allergic responses...
June 23, 2017: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/28606183/allergenic-activity-of-pseudoterranova-decipiens-nematoda-anisakidae-in-balb-c-mice
#11
Alessandra Ludovisi, Gabriella Di Felice, Noelia Carballeda-Sangiao, Bianca Barletta, Cinzia Butteroni, Silvia Corinti, Gianluca Marucci, Miguel González-Muñoz, Edoardo Pozio, Maria Angeles Gómez-Morales
BACKGROUND: Anisakis simplex is the only fishery-product associated parasite causing clinical allergic responses in humans so far. However, other anisakids, due to the presence of shared or own allergens, could also lead to allergic reactions after sensitization. The aim of this study was to determine if Pseudoterranova decipiens belonging to the family Anisakidae has allergenic activity and is able to induce sensitization after oral administration in a murine (BALB/c mice) model. RESULTS: The ingestion of A...
June 12, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28601540/atrial-fibrillation-in-anaphylaxis
#12
Patricia Rojas-Perez-Ezquerra, Blanca Noguerado-Mellado, Cristina Morales-Cabeza, Gabriela Zambrano Ibarra, Tomas Datino Romaniega
BACKGROUND: The relationship between anaphylaxis and cardiovascular events has been reported in the past. While skin and respiratory symptoms are usually the most common and the first to appear, cardiovascular complications play a key role and represent the leading cause of death in anaphylaxis. METHODS: We report 3 episodes of atrial fibrillation triggered by anaphylaxis. Allergy and cardiology studies were performed. In both patients, the etiological agent was identified: Anisakis simplex hypersensitivity and food allergy...
September 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28554526/quantitative-sybr-green-qpcr-technique-for-the-detection-of-the-nematode-parasite-anisakis-in-commercial-fish-derived-food
#13
Carla Godínez-González, Xavier Roca-Geronès, Beatriz Cancino-Faure, Isabel Montoliu, Roser Fisa
The extensive presence of anisakids in fish for human consumption has become a problem of food safety and quality. The aim of this study was to develop and assess the performance of a quantitative SYBR Green qPCR assay for the detection and quantification of Anisakis DNA in fish by-products. L3 nematode larvae of A. simplex (s.l.) (n=510), A. physeteris (n=3), Hysterothylacium sp. (n=10) and Pseudoterranova sp. (n=1), isolated from blue whiting, horse mackerel and monkfish, were used for the optimization of the molecular assay...
May 16, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28497226/anisakis-haemoglobin-is-a-main-antigen-inducing-strong-and-prolonged-immunoreactions-in-rats
#14
Niichiro Abe, Isao Teramoto
Anisakis simplex larvae are well known to cause gastrointestinal and allergic manifestations after ingestion of parasitized raw or undercooked seafood. The antibody recognition dynamics against the components of Anisakis larval antigen after primary and re-infection with Anisakis live larvae remain unclear. For this study, immunoblot analyses of serum IgG, IgE, and IgM against Anisakis larval somatic extract were performed in rats that had been orally inoculated with A. simplex live larvae. Multiple antigen fractions were recognized after primary infection...
July 2017: Parasitology Research
https://www.readbyqxmd.com/read/28366190/structural-characterization-of-as-mif-and-hjab1-during-the-inhibition-of-cell-cycle-regulation
#15
Young-Hoon Park, Mi Suk Jeong, Ki-Tae Ha, Hak Sun Yu, Se Bok Jang
The biological activities of macrophage migration inhibitory factor (MIF) might be mediated through a classical receptormediated or non-classical endocytic pathway. JAB1 (C-Jun activation domain-binding protein-1) promotes the degradation of the tumor suppressor, p53, and the cyclin-dependent kinase inhibitor, p27. When MIF and JAB1 are bound to each other in various intracellular sites, MIF inhibits the positive regulatory effects of JAB1 on the activity of AP-1. The intestinal parasite, Anisakis simplex, has an immunomodulatory effect...
May 2017: BMB Reports
https://www.readbyqxmd.com/read/28341528/molecular-diagnosis-of-allergy-to-anisakis-simplex-and-gymnorhynchus-gigas-fish-parasites
#16
A Armentia, J Santos, Z Serrano, B Martín, S Martín, J Barrio, S Fernández, M González-Sagrado, F Pineda, R Palacios
BACKGROUND: There has been an increase in the prevalence of hypersensitivity to Anisakis simplex. There are fish parasites other than Anisakis simplex whose allergenicity has not yet been studied. OBJECTIVE: To assess IgE hypersensitivity caused by fish parasite allergens in patients with gastro-allergic symptoms after consumption of fish, shellfish or cephalopods, compared with healthy subjects, pollen allergic individuals and children with digestive symptoms after eating marine food...
March 21, 2017: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/28299289/occurrence-of-nematodes-of-the-genus-anisakis-in-mediterranean-and-atlantic-fish-marketed-in-sardinia
#17
Daniele Casti, Christian Scarano, Maria Cristina Piras, Paolo Merella, Sonia Muglia, Francesca Piras, Giovanni Garippa, Carlo Spanu, Enrico Pietro Luigi De Santis
Anisakiasis is a gastrointestinal fish-borne zoonosis caused by the ingestion of third stage larvae of the genus Anisakis. Between January and December 2013, 1112 specimens of four commercial fish species (Engraulis encrasicolus, Merluccius merluccius, Scomber colias and Trachurus mediterraneus) marketed in Sardinia (Italy) were examined for Anisakis sp. The overall prevalence of Anisakis spp larvae was 39.9%, all morphologically identified as Type I. Scomber colias showed the highest prevalence (100%), followed by M...
January 24, 2017: Italian Journal of Food Safety
https://www.readbyqxmd.com/read/28294584/ige-igg1-and-igg4-response-to-specific-allergens-in-sensitized-subjects-showing-different-clinical-reactivity-to-anisakis-simplex
#18
M T Ventura, R Rodriguez-Perez, M L Caballero, M Garcia-Alonso, L Antonicelli, R Asero
Background. Anisakis simplex hypersensitive subjects may be sensitized without clinical allergy, or experience acute symptoms or chronic urticaria induced by raw fish. We studied whether the 3 subgroups differ in IgE, IgG1 or IgG4 reactivity to specific Anisakis simplex allergens. Methods. 28 Anisakis simplex-hypersensitive adults, 11 with acute symptoms, 9 with chronic urticaria, and 8 sensitized were studied. IgE, IgG1 and IgG4 to rAni s 1, 5, 9 and 10 were sought by ELISA. IgE and IgG4 to nAni s 4 were determined by WB...
March 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28168577/determination-of-anti-anisakis-simplex-antibodies-and-relationship-with-%C3%AE-%C3%AE-and-%C3%AE-%C3%AE-lymphocyte-subpopulations-in-patients-with-crohn-s-disease
#19
C Benet-Campos, C Cuéllar, C García-Ballesteros, V Zamora, R Gil-Borrás, I Catalán-Serra, F López-Chuliá, J C Andreu-Ballester
BACKGROUND: The etiology of Crohn's disease (CD) is still unknown although new theories are based on defects in innate immunity. We have previously shown a decrease in γδ T cells in CD patients. Previous studies have shown a high prevalence of anti-A. simplex immunoglobulins in CD patients. The diminution of γδ T cells in the peripheral blood and intestinal mucosa of CD patients may create a state of immunosuppression that would facilitate A. simplex infection. AIMS: To study the antibody responses to Anisakis antigens in Crohn's disease patients and its relationship with αβ and γδ T cell subsets...
April 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28126544/population-parameters-and-mito-nuclear-mosaicism-of-anisakis-spp-in-the-adriatic-sea
#20
Ivona Mladineo, Ivana Bušelić, Jerko Hrabar, Anamarija Vrbatović, Ivana Radonić
Recombinant genotypes of A. simplex sensu stricto (s.s.) and A. pegreffii, two species of Anisakis simplex complex found in sympatric waters of the Mediterranean Sea, are believed to be a product of interspecific hybridisation and/or DNA introgression. In contrast, such events within an allopatric area as the Adriatic Sea are unlikely to occur and therefore observed recombination should be assessed more closely. We have genotyped 525 anisakids collected from migratory and non-migratory fish of the southern part of the Adriatic Sea, inferring its omniparentage at nuclear (ITS locus) and matrilineage at mitochondrial locus (cox2)...
March 2017: Molecular and Biochemical Parasitology
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