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https://www.readbyqxmd.com/read/28719802/cerebral-hypoperfusion-is-not-associated-with-an-increase-in-%C3%AE-amyloid-pathology-in-middle-aged-or-elderly-people
#1
O Hansson, S Palmqvist, H Ljung, T Cronberg, D van Westen, R Smith
INTRODUCTION: It is hypothesized that cerebral hypoperfusion promotes the development of Alzheimer pathology. We therefore studied whether longstanding cerebral hypoperfusion is associated with Alzheimer pathology in nondemented humans. METHODS: Cerebral blood flow and β-amyloid ((18)F-Flutemetamol) positron emission tomography retention were assessed in eleven patients with unilateral occlusion of precerebral arteries resulting in chronic and uneven hypoperfusion...
July 15, 2017: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://www.readbyqxmd.com/read/28718269/non-atherosclerotic-obliteration-of-bilateral-supraclinoid-internal-carotid-arteries-a-classic-case-of-moyamoya-disease
#2
Saad Ullah, Anas Ahmed Siddiqui, Waseem Zaid Alkilani, Noman Ahmed Jang Khan, Hafiz Umair Siddiqui
Moyamoya disease is an idiopathic progressive vasculopathy of distal internal carotid artery and circle of Willis which leads to the development of characteristic smoky appearance of the vascular collateral network on angiography. With the highest reported incidence among Japanese population, it has been under recognized as a cause of cerebrovascular accidents in Western countries. Here we report a case of a young 20-year-old Caucasian woman who presented to the emergency department with expressive aphasia, right arm weakness and numbness for three days...
April 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28716673/application-of-3d-computerized-tomography-angiography-for-defining-cavernous-sinus-aneurysms-and-intradural-aneurysms-involving-the-internal-carotid-artery-around-the-anterior-clinoid-process
#3
Quan Cheng, Chun-Bo Huang, Jun-Yu Wang, Bing Jiang, Long-Bo Zhang, Ming Zeng, Yuan-Bing Chen, Hong-Fu Zhang, Feng-Hua Chen
OBJECTIVE: The current study aimed to investigate the application of three-dimensional computed tomography angiography (3D-CTA) for defining cavernous sinus aneurysms and intradural aneurysms involving the internal carotid artery around the anterior clinoid process. METHODS: Results from 42 patients with an aneurysm of the internal carotid artery around the anterior clinoid process who underwent 3D-CTA were reviewed and compared with those of observed clinical operations...
July 14, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28716586/comparison-of-three-dimensional-t1-weighted-magnetic-resonance-and-contrast-enhanced-ultrasound-plaque-images-for-severe-stenosis-of-the-cervical-carotid-artery
#4
Yasuyoshi Shimada, Kohki Oikawa, Shunrou Fujiwara, Yasushi Ogasawara, Yuiko Sato, Shinsuke Narumi, Tadayoshi Kato, Kazumasa Oura, Yasuo Terayama, Makoto Sasaki, Kentaro Fujimoto, Jun Yoshida, Kuniaki Ogasawara
BACKGROUND AND PURPOSE: Magnetic resonance (MR) and contrast-enhanced ultrasound assess characteristics and neovascularization, respectively, of the carotid plaque. The purpose of the present study was to clarify how findings of contrast-enhanced ultrasound plaque imaging are related to those of 3-dimensional (3D) fast spin echo (FSE) T1-weighted MR plaque imaging (WI) in severe stenosis (≥70%) of the cervical carotid artery. METHODS: Fifty-three patients underwent 3D FSE T1-WI and contrast-enhanced ultrasound...
July 14, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28716303/early-results-of-endovascular-treatment-of-patients-with-bilateral-stenoses-of-the-internal-carotid-arteries-using-proximal-protection-systems-at-30-day-follow-up
#5
Paweł Latacz, Marian Simka, Tadeusz Popiela, Marek Kazibudzki, Tomasz Mrowiecki
BACKGROUND: Although surgical endarterectomy remains the treatment of choice for carotid artery stenosis, carotid artery stenting (CAS) with use of proximal protection systems (PPS) plays an very important role as alternative treatment modality, especially in patients with critical, symptomatic lesions. This study was single-centre study to evaluate the technical and clinical success of proximal protection devices as the first choice for embolic protection in symptomatic and asymptomatic carotid stenosis in patients with bilateral, advanced lesions of carotid arteries (bilateral stenoses or stenosis and occlusion)...
July 8, 2017: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/28715558/prevalence-of-intracranial-aneurysm-in-women-with-fibromuscular-dysplasia-a-report-from-the-us-registry-for-fibromuscular-dysplasia
#6
Henry D Lather, Heather L Gornik, Jeffrey W Olin, Xiaokui Gu, Steven T Heidt, Esther S H Kim, Daniella Kadian-Dodov, Aditya Sharma, Bruce Gray, Michael R Jaff, Yung-Wei Chi, Pamela Mace, Eva Kline-Rogers, James B Froehlich
Importance: The prevalence of intracranial aneurysm in patients with fibromuscular dysplasia (FMD) is uncertain. Objective: To examine the prevalence of intracranial aneurysm in women diagnosed with FMD. Design, Setting, and Participants: This cross-sectional study included 669 women with intracranial imaging registered in the US Registry for Fibromuscular Dysplasia, an observational disease-based registry of patients with FMD confirmed by vascular imaging and currently enrolling at 14 participating US academic centers...
July 17, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28715234/is-cardiovascular-disease-in-patients-with-diabetes-associated-with-serum-levels-of-mmp-2-lox-and-the-elastin-degradation-products-elm-and-elm-2
#7
Simone Andrea Rørdam Preil, Anne-Sofie Faarvang Thorsen, Anne Lindegaard Christiansen, Mikael Kjær Poulsen, Morten Asser Karsdal, Diana Julie Leeming, Lars Melholt Rasmussen
BACKGROUND: Diabetes mellitus type 2 (T2DM) is a significant risk factor for the development of cardiovascular diseases (CVDs). In a previous microarray study of internal mammary arteries from patients with and without T2DM, we observed several elastin-related genes with altered mRNA-expression in diabetic patients, namely matrix metalloproteinase 2 (MMP-2), lysyl oxidase (LOX) and elastin itself. In this study we investigate whether the serum concentrations of elastin-related proteins correlate to signs of CVD in patients with T2DM...
July 17, 2017: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/28712899/iatrogenic-ascending-pharyngeal-artery-injury-by-pre-dilation-balloon-inflation-during-carotid-artery-stenting-with-flow-reversal
#8
Junpei Koge, Tomonori Iwata, Shigehisa Mizuta, Yukihiko Nakamura, Shun-Ichi Matsumoto, Takeshi Yamada
BACKGROUND: The ascending pharyngeal artery (APA) may rarely arise from the common carotid artery bifurcation. We herein report an injury to the APA as an unusual complication of pre-dilation balloon inflation during carotid artery stenting (CAS) with flow reversal. CASE DESCRIPTION: A 73-year-old man presented with symptomatic severe left cervical internal carotid artery (ICA) stenosis. The left APA arose from the common carotid artery bifurcation. We performed CAS with flow reversal to decrease the risk of distal embolization...
July 13, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28710049/trans-anterior-communicating-artery-primary-stenting-in-acute-tandem-middle-cerebral-artery-internal-carotid-artery-occlusion-due-to-thoracic-aortic-stent-graft
#9
Sergio Nappini, Nicola Limbucci, Giuseppe Leone, Antonio Laiso, Andrea Wlderk, Salvatore Mangiafico
No abstract text is available yet for this article.
July 11, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28710044/treatment-strategies-of-subarachnoid-hemorrhage-from-bilateral-vertebral-artery-dissection-a-case-report-and-literature-review-focusing-on-availability-of-stent-placement
#10
Yasuo Murai, Fumihiro Matano, Shoji Yokobori, Hidetaka Onda, Hiroyuki Yokota, Akio Morita
BACKGROUND: Bilateral vertebral artery dissection (VAD) may result in subarachnoid hemorrhage (SAH). However, a variety of factors contribute to the difficulties with treating SAH. We report a case of bilateral VAD with SAH, as well as a literature review. CASE DESCRIPTION: A 32-year-old woman developed headache. Computed tomography (CT) demonstrated diffuse SAH, and 3-dimensional CT indicated bilateral VAD. Her left vertebral artery was severely stenosed and the basilar artery was retrogradely flowed via the posterior communicating artery...
July 11, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28709707/endovascular-treatment-of-acute-ischemic-stroke-with-eric-device
#11
Laurent Pierot, Jean-Yves Gauvrit, Vincent Costalat, Michel Piotin, Charbel Mounayer, Denis Herbreteau, Sophie Gallas, René Anxionnat, Hubert Desal
BACKGROUND AND PURPOSE: After 6 positive randomized trials, mechanical thrombectomy with stent-retriever is now recommended as a first-line treatment for acute ischemic stroke (AIS). The ERIC device is a device with several interlinked cage-like spheres fixed on a pusher wire. Neurothrombectomy France (NTF) is a registry conducted in France to analyze the results of mechanical thrombectomy. In order to analyze its performances, the subgroup of patients treated with the ERIC device was analyzed...
July 11, 2017: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/28705843/headache-tia-and-subarachnoid-haemorrhage-dissecting-an-unusual-cause-for-stroke-like-symptoms
#12
Elliot T Dawson, Desmond A Brown, Alejandro A Rabinstein
We present a case of supraclinoid internal carotid artery dissection. Eleven months prior, the patient developed isolated periorbital pain and was diagnosed with giant-cell arteritis with iritis. The patient experienced recurrent spells concerning for transient ischaemic attacks and was transferred to our institution for endovascular intervention after head CT revealed an embolic infarct with a 'dense middle cerebral artery sign.' Digital subtraction angiography was negative for occlusion, instead demonstrating luminal stenosis and poststenotic dilatation...
July 13, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28705342/unruptured-multiple-intracranial-aneurysms-associated-with-beh%C3%A3-et-s-disease
#13
N Belfeki, K Argillos, R Dahmani, A Fkihi, N Velmans
Behçet's disease is a systemic inflammatory disorder with a wide variety of cardiovascular complications. Intracranial aneurysm is extremely rare. Herein, we are presenting a 41-year-old male with Behçet's disease and a headache. A cranial computed tomography scan angiography showed unruptured right supra cavernus internal carotid aneurysm and right sylvian artery aneurysm. Treatment consisted of prednisone and azathioprine. Control imaging showed no aneurysm.
July 2017: J Med Vasc
https://www.readbyqxmd.com/read/28700499/cerebrovascular-risk-factors-for-patients-with-cerebral-watershed-infarction-a-case-control-study-based-on-computed-tomography-angiography-in-a-population-from-southwest-china
#14
Mei-Xue Dong, Ling Hu, Yuan-Jun Huang, Xiao-Min Xu, Yang Liu, You-Dong Wei
To determine cerebrovascular risk factors for patients with cerebral watershed infarction (CWI) from Southwest China.Patients suffering from acute ischemic stroke were categorized into internal CWI (I-CWI), external CWI (E-CWI), or non-CWI (patients without CWI) groups. Clinical data were collected and degrees of steno-occlusion of all cerebral arteries were scored. Arteries associated with the circle of Willis were also assessed. Data were compared using Pearson chi-squared tests for categorical data and 1-way analysis of variance with Bonferroni post hoc tests for continuous data, as appropriate...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28699679/one-session-of-remote-ischemic-preconditioning-does-not-improve-vascular-function-in-acute-normobaric-and-chronic-hypobaric-hypoxia
#15
Mathew G Rieger, Ryan L Hoiland, Joshua C Tremblay, Mike Stembridge, Anthony R Bain, Daniela Flück, Prajan Subedi, James D Anholm, Philip N Ainslie
Application of repeated short duration bouts of ischemia to the limbs, termed remote ischemic preconditioning (RIPC), is a novel technique that may have protective effects on vascular function during hypoxic exposures. In separate parallel-design studies, at sea-level (SL; n = 16), and after 8-12 days at high-altitude (HA; n = 12; White Mountain, 3800 m), participants underwent either a sham protocol or one session of 4 × 5 minutes of dual-thigh cuff occlusion with 5 minutes recovery. Brachial artery flow-mediated dilation (FMD; ultrasound), pulmonary artery systolic pressure (PASP; echocardiography), and internal carotid artery flow (ICA; ultrasound) were measured at SL in normoxia and isocapnic hypoxia [end-tidal PO₂ (PETO₂) maintained to 50 mmHg], and during normal breathing at HA...
July 12, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28698909/the-cisternal-segment-of-the-anterior-choroidal-artery-an-anatomical-study-using-magnetic-resonance-imaging
#16
Satoshi Tsutsumi, Hideo Ono, Yukimasa Yasumoto
PURPOSE: The topography of the anterior choroidal artery (AChA) has infrequently been delineated on neuroimages. The present study aimed to explore the cisternal segment of the AChA using magnetic resonance imaging. METHODS: A total of 50 sides of the AChA obtained from 25 patients were included in this study. A constructive interference in steady-state (CISS) sequence was performed in thin-sliced axial sections. Furthermore, the cisternal AChA and relevant neurovascular structures were observed through cadaveric dissections in two heads...
July 11, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28694612/cerebral-and-coronary-vasculature-in-disease-associations-and-dissociations-in-the-south-indian-population
#17
Krishnan Srinivasan, Srinivasan Ravikumar, Sadanandavalli Retnaswami Chandra, Selva Ganapathy, G S Ravi
INTRODUCTION: Cerebrovascular accidents constitute the most common cause of disability all over the world. In India prevalence rate is 545 per 100000 and mortality rate is around 7.5 per thousand. Therefore the authors undertook a study on patients who underwent coronary artery bypass surgery (CABG). They were investigated for clinical and/or radiological evidence of cerebrovascular disease (CVD) with the aim to decide on early neurological intervention. PATIENTS AND METHODS: 210 patients who had undergone CABG were evaluated with neck vessel Doppler using high resolution duplex scanner system and computed tomography (CT) scan as well as MR angiogram (MRA) in addition to assessment of co morbid risk factors...
July 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28694608/surgically-relevant-bony-anatomical-variations-in-paraclinoid-aneurysms-three-dimensional-multi-detector-row-computed-tomography-based-study
#18
K Suprasanna, Ashvini Kumar
OBJECTIVE: To evaluate the proportion of surgically relevant anatomical variations such as caroticoclinoid foramen, interclinoid osseous bridge, and anterior clinoid pneumatization in patients with paraclinoid aneurysms based on computed tomography (CT) cerebral angiography studies. MATERIALS AND METHODS: Fifty-four CT cerebral angiography studies showing paraclinoid aneurysms involving the cavernous, clinoid, and supraclinoid internal carotid artery (ICA) were retrospectively evaluated...
July 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28694111/the-pathophysiology-of-watershed-infarction-a-three-dimensional-time-of-flight-magnetic-resonance-angiography-study
#19
Caroline Weill, Laurent Suissa, Jacques Darcourt, Marie-Hélène Mahagne
BACKGROUND: Most of the time, watershed infarcts (WIs) involve steno-occlusive carotid disease. The pathophysiological mechanism could be predicted by their pattern: internal WIs (IWIs) are thought to be due to hemodynamic impairment in contrast to cortical WIs (CWIs), which are more likely to be caused by microembolic phenomena. We used a 3D time-of-flight (TOF) magnetic resonance angiography (MRA) study to assess this hypothesis. METHODS: In 45 consecutive patients with a recent WI and ipsilateral cervical carotid stenosis, clinical and radiological data were obtained retrospectively...
July 7, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28693985/cardiovascular-risk-markers-among-obese-women-using-the-levonorgestrel-releasing-intrauterine-system-a-randomised-controlled-trial
#20
Lucimara Facio Nobre Zueff, Anderson Sanches de Melo, Carolina S Vieira, Wellington P Martins, Rui A Ferriani
According to international guidelines, women with obesity without other comorbidities can safely use any hormonal contraceptive (HC). However, limited information is available about contraceptive safety for women with obesity since obesity is an exclusion criterion of most contraceptive clinical trials. As such little is known about the possible risks of HC exposure for women with obesity without comorbidities. One way to assess possible long-term risks in this population, even prior to the development of any clinical disease, is to measure alterations in subclinical atherosclerosis markers...
July 7, 2017: Obesity Research & Clinical Practice
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