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https://www.readbyqxmd.com/read/28806283/expanding-the-scope-of-quality-measurement-in-surgery-to-include-non-operative-care-results-from-the-acs-nsqip-emergency-general-surgery-pilot
#1
Michael W Wandling, Clifford Y Ko, Paul E Bankey, Chris Cribari, H Gill Cryer, Jose J Diaz, Therese M Duane, S Morad Hameed, Matthew M Hutter, Michael H Metzler, Justin L Regner, Patrick M Reilly, H David Reines, Jason L Sperry, Kristan L Staudenmayer, Garth H Utter, Marie L Crandall, Karl Y Bilimoria, Avery B Nathens
BACKGROUND: Patients managed non-operatively have been excluded from risk-adjusted benchmarking programs, including the American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP). Consequently, optimal performance evaluation is not possible for specialties like emergency general surgery (EGS) where non-operative management is common. We developed a multi-institutional EGS clinical data registry within ACS NSQIP that includes patients managed non-operatively to evaluate variability in non-operative care across hospitals and identify gaps in performance assessment that occur when only operative cases are considered...
August 12, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28802162/efficient-dynamic-graph-construction-for-inductive-semi-supervised-learning
#2
F Dornaika, R Dahbi, A Bosaghzadeh, Y Ruichek
Most of graph construction techniques assume a transductive setting in which the whole data collection is available at construction time. Addressing graph construction for inductive setting, in which data are coming sequentially, has received much less attention. For inductive settings, constructing the graph from scratch can be very time consuming. This paper introduces a generic framework that is able to make any graph construction method incremental. This framework yields an efficient and dynamic graph construction method that adds new samples (labeled or unlabeled) to a previously constructed graph...
July 24, 2017: Neural Networks: the Official Journal of the International Neural Network Society
https://www.readbyqxmd.com/read/28799135/appendiceal-duplication-a-comprehensive-review-of-published-cases-and-clinical-recommendations
#3
H Nageswaran, U Khan, F Hill, A Maw
BACKGROUND: Duplex appendix is very rare (incidence 0.004%) but has clinical relevance given the frequency of appendicectomies performed. Failure to recognise duplication can result in failure of treatment and medico-legal consequences. A review of published cases was undertaken to identify factors that may help in managing this rare condition. METHODS: All English and non-English publications were identified in PubMed, Embase and Cochrane databases. Patient demographics, intraoperative findings, anatomical details and histopathology were analysed...
August 10, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28798242/a-rare-urological-presentation-of-appendicitis
#4
Nick Simson, Thomas Stonier, Alberto Coscione, Ahmed Qteishat
A 17-year-old boy with no medical comorbidities, but a significant family history of malignancy, presented to Accident and Emergency following 3 days of increasing rectal pain, symptoms of bladder outflow obstruction (poor flow, intermittent stream and hesitancy) and dysuria. Notably he had no abdominal pain. Digital rectal examination revealed a tender, enlarged prostate. Inflammatory markers were significantly raised (white cell count 17.7, C reactive protein 191). He was diagnosed clinically as prostatitis and commenced on intravenous antibiotics...
August 10, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28797333/can-the-diagnosis-of-appendicitis-be-made-without-a-computed-tomography-scan
#5
REVIEW
Yangyang R Yu, Sohail R Shah
No abstract text is available yet for this article.
September 2017: Advances in Surgery
https://www.readbyqxmd.com/read/28797332/can-surgery-for-appendicitis-be-performed-as-an-outpatient-procedure
#6
REVIEW
Richard Frazee
No abstract text is available yet for this article.
September 2017: Advances in Surgery
https://www.readbyqxmd.com/read/28796552/diagnostic-accuracy-of-mri-versus-ct-for-the-evaluation-of-acute-appendicitis-in-children-and-young-adults
#7
Sonja Kinner, Perry J Pickhardt, Erica L Riedesel, Kara G Gill, Jessica B Robbins, Douglas R Kitchin, Timothy J Ziemlewicz, John B Harringa, Scott B Reeder, Michael D Repplinger
OBJECTIVE: Appendicitis is frequently diagnosed in the emergency department, most commonly using CT. The purpose of this study was to compare the diagnostic accuracy of contrast-enhanced MRI with that of contrast-enhanced CT for the diagnosis of appendicitis in adolescents when interpreted by abdominal radiologists and pediatric radiologists. SUBJECTS AND METHODS: Our study included a prospectively enrolled cohort of 48 patients (12-20 years old) with nontraumatic abdominal pain who underwent CT and MRI...
August 10, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28796014/comparison-of-superficial-surgical-site-infection-between-delayed-primary-versus-primary-wound-closure-in-complicated-appendicitis-a-randomized-controlled-trial
#8
Boonying Siribumrungwong, Anuwat Chantip, Pinit Noorit, Chumpon Wilasrusmee, Winai Ungpinitpong, Pradya Chotiya, Borwornsom Leerapan, Patarawan Woratanarat, Mark McEvoy, John Attia, Ammarin Thakkinstian
OBJECTIVE: To compare superficial surgical site infection (SSI) rates between delayed primary wound closure (DPC) and primary wound closure (PC) for complicated appendicitis. BACKGROUND: SSI is common in appendectomy for complicated appendicitis. DPC is preferentially used over PC, but its efficacy is still controversial. METHODS: A multicenter randomized controlled trial was conducted in 6 hospitals in Thailand, enrolling patients with gangrenous and ruptured appendicitis...
August 4, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28794548/informed-consent-process-foundation-of-the-researcher-participant-bond
#9
Amrita Sil, Nilay Kanti Das
Consenting to participate in a clinical research study after being properly and correctly informed upholds the basic ethical principle of "autonomy" in human research. The informed consent is a process by which the physician sensitizes the patient about the nature, procedures, risks benefits, treatment schedules, etc of the study in a language that is non-technical and understandable by the study participant. Informed consent document (ICD) has got two parts: the 'Subject Information Sheet' and the 'Informed Consent Form' (ICF); and they have to be approved by the Institutional Ethics Committee (IEC) before administration...
July 2017: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/28793826/toxoplasma-appendicitis-a-once-in-a-lifetime-diagnosis
#10
Anisha M Fernandes, Maheshkumar M Lakhe, Sanjay A Pai
Toxoplasmosis is generally asymptomatic in immunocompetent individuals, but it can be life-threatening in immunocompromised patients. We present a case of a 62-year-old man with clinical features of acute appendicitis. Histology showed a transmural infiltrate of eosinophils. In addition, there were reactive lymphoid follicles with histiocytes in the submucosa and tachyzoites in the muscularis propria. Immunohistochemistry confirmed the diagnosis of toxoplasma appendicitis. Serological evaluation yielded negative results...
August 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28793279/a-case-of-lower-digestive-tract-hemorrhage-caused-by-appendicitis-in-china
#11
Zhen Shen, Yan-Zhi Huang, Li-Min Ning, Hai-Cheng Gao, Wei Wang
In this case, we report a case of lower digestive tract hemorrhage caused by appendicitis in China. An 46-year-old Chinese male was sent to China-Japan union Hospital of Jilin University with abdominal pain in 2015. The patient was diagnosed with anemia. In this report, the appendix of patient was excised by laparoscopic surgery. The patient's colonoscopy results showed patient could be seen a large number of dark red blood and fresh blood in the intestinal cavity. The patient's colon position found focal mucosal shedding, shallow ulcer formation...
July 5, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28782355/tetraalkoxyphenanthrene-fused-hexadecadehydro-20-and-tetracosadehydro-30-annulenes-syntheses-aromaticity-antiaromaticity-electronic-properties-and-self-assembly
#12
Nobutaka Takahashi, Shin-Ichiro Kato, Minoru Yamaji, Masahiko Ueno, Ryunosuke Iwabuchi, Yui Shimizu, Masashi Nitani, Yutaka Ie, Yoshio Aso, Takeshi Yamanobe, Hiroki Uehara, Yosuke Nakamura
Tetraalkoxyphenanthrene-fused hexadecadehydro[20]- and tetracosadehydro[30]annulenes possessing octatetrayne linkages were synthesized and their properties together with those of phenanthrene-fused octadehydro[12]- and dodecadehydro[18]annulenes have been investigated. Various spectroscopic and electrochemical measurements as well as quantum chemical calculations support that planar [20]- and [30]annulenes are weakly antiaromatic and nonaromatic, respectively. The detailed concentration- and temperature-dependent 1H NMR and UV-vis data of present dehydroannulenes provided evidence for the enhancement of π-π stacking interactions by extension of the acetylenic linkages...
August 7, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28780543/electroacupuncture-to-alleviate-postoperative-pain-after-a-laparoscopic-appendectomy-study-protocol-for-a-three-arm-randomised-controlled-trial
#13
Seunghoon Lee, Dongwoo Nam, Minsoo Kwon, Won Seo Park, Sun Jin Park
BACKGROUND: The purpose of this study is to evaluate the efficacy and safety of electroacupuncture (EA) for postoperative pain after laparoscopic appendectomy compared with sham electroacupuncture (SEA) and no acupuncture treatment. METHODS AND ANALYSIS: This study is a protocol for a three-arm, randomised, patient-assessor-blinded (to the type of acupuncture treatment), controlled, parallel trial. 138 participants diagnosed with appendicitis and scheduled for laparoscopic appendectomy will be randomly assigned to the EA group (n=46), SEA group (n=46) or control group (n=46)...
August 4, 2017: BMJ Open
https://www.readbyqxmd.com/read/28778030/development-and-application-of-a-novel-fluorescent-nanosensor-based-on-fese-quantum-dots-embedded-silica-molecularly-imprinted-polymer-for-the-rapid-optosensing-of-cyfluthrin
#14
Xunjia Li, Hai-Feng Jiao, Xi-Zhi Shi, Aili Sun, Xiujuan Wang, Jiye Chai, De-Xiang Li, Jiong Chen
A novel molecularly imprinted silica layer appended to FeSe quantum dots (MIP-FeSe-QDs) was fabricated and utilized as a recognition element to develop a selective and sensitive fluorescent nanosensor for cyfluthrin (CYF) determination. The MIP-FeSe-QDs were characterized by fluorescence spectrometry, scanning electron microscopy, transmission electron microscopy, and Fourier transform infrared spectroscopy. Excellent selectivity and high sensitivity of MIP-FeSe-QDs to CYF molecules were observed based on the fluorescence quenching of FeSe-QDs...
July 29, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28777537/pushing-chemical-boundaries-with-n-heterocyclic-olefins-nhos-from-catalysis-to-main-group-element-chemistry
#15
Matthew M D Roy, Eric Rivard
N-Heterocyclic olefins (NHOs) have gone from the topic of a few scattered (but important) reports in the early 1990s to very recently being a ligand/reagent of choice in the far-reaching research fields of organocatalysis, olefin and heterocycle polymerization, and low oxidation state main group element chemistry. NHOs are formally derived by appending an alkylidene (CR2) unit onto an N-heterocyclic carbene (NHC), and their pronounced ylidic character leads to high nucleophilicity and soft Lewis basic character at the ligating carbon atom...
August 4, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28770399/triphenylphosphonium-desferrioxamine-as-a-candidate-mitochondrial-iron-chelator
#16
Roxana Y P Alta, Hector A Vitorino, Dibakar Goswami, M Terêsa Machini, Breno P Espósito
Cell-impermeant iron chelator desferrioxamine (DFO) can have access to organelles if appended to suitable vectors. Mitochondria are important targets for the treatment of iron overload-related neurodegenerative diseases. Triphenylphosphonium (TPP) is a delocalized lipophilic cation used to ferry molecules to mitochondria. Here we report the synthesis and characterization of the conjugate TPP-DFO as a mitochondrial iron chelator. TPP-DFO maintained both a high affinity for iron and the antioxidant activity when compared to parent DFO...
August 2, 2017: Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine
https://www.readbyqxmd.com/read/28770136/neonatal-perforated-appendicitis-masquerading-as-necrotizing-enterocolitis
#17
Andrew Tumen, Pranit N Chotai, John Matthew Williams, Adrianne Myers-Webb, Jie Zhang, Ramesh Krishnan, James W Eubanks Iii
A preterm neonate underwent emergent laparotomy for presumed necrotizing enterocolitis (NEC). Intra-operatively, neonatal perforated appendicitis (NPA) was encountered. This may represent a form of NEC localized to the appendix. A high index of clinical suspicion and early laparotomy are recommended.
April 2017: Journal of Neonatal Surgery
https://www.readbyqxmd.com/read/28766938/rhenium-and-technetium-oxo-complexes-with-thioamide-derivatives-of-pyridylhydrazine-bifunctional-chelators-conjugated-to-the-tumour-targeting-peptides-octreotate-and-cyclic-rgdfk
#18
Andrea J North, John A Karas, Michelle T Ma, Philip J Blower, Uwe Ackermann, Jonathan M White, Paul S Donnelly
This research aimed to develop new tumor targeted theranostic agents taking advantage of the similarities in coordination chemistry between technetium and rhenium. A γ-emitting radioactive isotope of technetium is commonly used in diagnostic imaging, and there are two β(-) emitting radioactive isotopes of rhenium that have the potential to be of use in radiotherapy. Variants of the 6-hydrazinonicotinamide (HYNIC) bifunctional ligands have been prepared by appending thioamide functional groups to 6-hydrazinonicotinamide to form pyridylthiosemicarbazide ligands (SHYNIC)...
August 2, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28766636/enhanced-free-energy-of-extraction-of-eu-3-and-am-3-ions-towards-diglycolamide-appended-calix-4-arene-insights-from-dft-d3-and-cosmo-rs-solvation-models
#19
Sk Musharaf Ali
Density functional theory in conjunction with COSMO and COSMO-RS solvation models employing dispersion correction (DFT-D3) has been applied to gain an insight into the complexation of Eu(3+)/Am(3+) with diglycolamide (DGA) and calix[4]arene appended diglycolamide (CAL4DGA) in ionic liquids by studying structures, energetics, thermodynamics and population analysis. The calculated Gibbs free energy for both Eu(3+) and Am(3+) ions with DGA was found to be smaller than that with CAL4DGA. The entropy of complexation was also found to be reduced to a large extent with DGA compared to complexation with CAL4DGA...
August 2, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28764185/kikuchi-fujimoto-disease-masquerading-as-acute-appendicitis
#20
Vinita Pandey, Yasmeen Khatib, Rahul Pandey, Archana L Khade, Manisha Khare
Kikuchi-Fujimoto Disease (KFD) is a self-limiting necrotizing lymphadenitis that usually presents with fever and cervical lymphadenopathy. Recognition of this condition is crucial, because it can be mistaken for tuberculosis, lymphoma and connective tissue disorders. When present at an unusual location the diagnosis can be challenging. We present an unusual case of Kikuchi-Fujimoto disease involving mesenteric lymph node masquerading as acute appendicitis along with its differential diagnosis. A 30-year-old female presented with complaints of acute abdominal pain, vomiting and fever...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
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