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Neurovascular imaging

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https://www.readbyqxmd.com/read/28090802/functional-deficits-induced-by-cortical-microinfarcts
#1
Philipp M Summers, David A Hartmann, Edward S Hui, Xingju Nie, Rachael L Deardorff, Emilie T McKinnon, Joseph A Helpern, Jens H Jensen, Andy Y Shih
Clinical studies have revealed a strong link between increased burden of cerebral microinfarcts and risk for cognitive impairment. Since the sum of tissue damage incurred by microinfarcts is a miniscule percentage of total brain volume, we hypothesized that microinfarcts disrupt brain function beyond the injury site visible to histological or radiological examination. We tested this idea using a mouse model of microinfarcts, where single penetrating vessels that supply mouse cortex were occluded by targeted photothrombosis...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28089656/how-do-antidepressants-influence-the-bold-signal-in-the-developing-brain
#2
REVIEW
Julia J Harris, Clare Reynell
Depression is a highly prevalent life-threatening disorder, with its first onset commonly occurring during adolescence. Adolescent depression is increasingly being treated with antidepressants, such as fluoxetine. The use of medication during this sensitive period of physiological and cognitive brain development produces neurobiological changes, some of which may outlast the course of treatment. In this review, we look at how antidepressant treatment in adolescence is likely to alter neurovascular coupling and brain energy use and how these changes, in turn, affect our ability to identify neuronal activity changes between participant groups...
December 21, 2016: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/28087356/long-term-sensitivity-and-patient-reported-functionality-of-the-neoclitoris-after-gender-reassignment-surgery
#3
Hannes Sigurjónsson, Caroline Möllermark, Johan Rinder, Filip Farnebo, T Kalle Lundgren
INTRODUCTION: A cornerstone of treating gender dysphoria for transgender women is gender reassignment surgery (GRS) encompassing vaginoplasty and clitoroplasty. The neoclitoris is harvested as a flap with a neurovascular pedicle from the proximal dorsal part of the glans penis. Few long-term follow-ups exist on postoperative sensation and patient-reported sexual functionality of the neoclitoris. AIM: To examine the sensitivity of the neoclitoris and its relation to orgasm and sexual function at least 1 year after GRS...
January 10, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28069927/impact-of-altered-cholinergic-tones-on-the-neurovascular-coupling-response-to-whisker-stimulation
#4
Clotilde Lecrux, Claire H Sandoe, Sujaya Neupane, Pascal Kropf, Xavier Toussay, Xin-Kang Tong, María Lacalle-Aurioles, Amir Shmuel, Edith Hamel
Brain imaging techniques that use vascular signals to map changes in neuronal activity rely on the coupling between electrophysiology and hemodynamics, a phenomenon referred to "neurovascular coupling" (NVC). It is unknown whether this relationship remains reliable under altered brain states associated to acetylcholine (ACh) levels, such as attention and arousal, and in pathological conditions like Alzheimer's disease. We therefore assessed the effects of varying ACh tone on whisker evoked-NVC responses in rat barrel cortex, measured by cerebral blood flow (CBF) and neurophysiological recordings (local field potentials, LFPs)...
January 9, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28065874/is-complex-sphenoidal-sinus-anatomy-a-contraindication-to-a-transsphenoidal-approach-for-resection-of-sellar-lesions-presentation-of-a-case-series-and-review-of-the-literature
#5
Marco Locatelli, Andrea Di Cristofori, Riccardo Draghi, Giulio Bertani, Claudio Guastella, Lorenzo Pignataro, Giovanna Mantovani, Paolo Rampini, Giorgio Carrabba
BACKGROUND: The transsphenoidal approach (TNS) is considered the gold standard for resection of pituitary adenomas and other sellar region lesions. This approach is guided by few fundamental anatomical landmarks that conduct the surgeon toward the sellar floor. Some anatomical structures may vary a lot (e.g. intrasphenoidal septa, intercarotid distance) and may be difficult to identify. Among those structures, the pneumatization and conformation of the sphenoidal sinus (SS) plays a key role for accessing the floor of the sella and other skull base structures...
January 5, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28063126/a-retrospective-study-of-neurocombing-for-the-treatment-of-trigeminal-neuralgia-without-neurovascular-compression
#6
X Liang, X Dong, S Zhao, X Ying, Y Du, W Yu
BACKGROUND: Microvascular decompression (MVD) is the most effective and non-ablative treatment for trigeminal neuralgia (TN). However, it is not possible when neurovascular compression (NVC) is absent. Neurocombing is a possible treatment option for TN patients without NVC. AIM: To evaluate and describe the clinical outcome of neurocombing for the treatment of TN when NVC was absent. METHODS: We retrospectively reviewed the clinical data of the 37 patients of Type 1 TN without NVC who underwent neurocombing in our department between January 2013 and November 2014...
January 6, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28053036/pericytes-as-inducers-of-rapid-matrix-metalloproteinase-9-dependent-capillary-damage-during-ischemia
#7
Robert G Underly, Manuel Levy, David A Hartmann, Roger I Grant, Ashley N Watson, Andy Y Shih
: Blood-brain barrier disruption (BBB) and release of toxic blood molecules into the brain contributes to neuronal injury during stroke and other cerebrovascular diseases. While pericytes are builders and custodians of the BBB in the normal brain, their impact on BBB integrity during ischemia remains unclear. We imaged pericyte-labeled transgenic mice with in vivo two-photon microscopy to examine the relationship between pericytes and blood plasma leakage during photothrombotic occlusion of cortical capillaries...
January 4, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28050345/functional-mri-vs-navigated-tms-to-optimize-m1-seed-volume-delineation-for-dti-tractography-a-prospective-study-in-patients-with-brain-tumours-adjacent-to-the-corticospinal-tract
#8
Carolin Weiss Lucas, Irada Tursunova, Volker Neuschmelting, Charlotte Nettekoven, Ana-Maria Oros-Peusquens, Gabriele Stoffels, Andrea Maria Faymonville, Shah N Jon, Karl Josef Langen, Hannah Lockau, Roland Goldbrunner, Christian Grefkes
BACKGROUND: DTI-based tractography is an increasingly important tool for planning brain surgery in patients suffering from brain tumours. However, there is an ongoing debate which tracking approaches yield the most valid results. Especially the use of functional localizer data such as navigated transcranial magnetic stimulation (nTMS) or functional magnetic resonance imaging (fMRI) seem to improve fibre tracking data in conditions where anatomical landmarks are less informative due to tumour-induced distortions of the gyral anatomy...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28048926/su-f-j-167-use-of-mr-for-permanent-prostate-implant-preplanning
#9
V Narayana, B Yao, P McLaughlin
PURPOSE: To study the feasibility using MR imaging to improve target definition on ultrasound during permanent prostate implants and aid in source strength determination for treatment planning in the OR. METHODS: Patients who receive permanent prostate implants undergo MR and CT imaging prior to the implant procedure to determine the volume of the prostate, bony restriction to the procedure, bladder extension, external sphincter length and neurovascular bundle. The volume of the prostate is generally used to order seeds for the procedure...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048545/we-de-207a-04-advances-in-radiological-neuro-endovascular-interventional-imaging
#10
S Rudin
: 1. Parallels in the evolution of x-ray angiographic systems and devices used for minimally invasive endovascular therapy Charles Strother - DSA, invented by Dr. Charles Mistretta at UW-Madison, was the technology which enabled the development of minimally invasive endovascular procedures. As DSA became widely available and the potential benefits for accessing the cerebral vasculature from an endovascular approach began to be apparent, industry began efforts to develop tools for use in these procedures...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048454/we-de-207a-00-advances-in-image-guided-neurointerventions-clinical-pull-and-technology-push
#11
Jeffrey Siewerdsen, Rebecca Fahrig
: 1. Parallels in the evolution of x-ray angiographic systems and devices used for minimally invasive endovascular therapy Charles Strother - DSA, invented by Dr. Charles Mistretta at UW-Madison, was the technology which enabled the development of minimally invasive endovascular procedures. As DSA became widely available and the potential benefits for accessing the cerebral vasculature from an endovascular approach began to be apparent, industry began efforts to develop tools for use in these procedures...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047932/tu-h-campus-iep3-02-neurovascular-4d-parametric-imaging-using-co-registration-of-biplane-dsa-sequences-with-3d-vascular-geometry-obtained-from-cone-beam-ct
#12
A Balasubramoniam, D Bednarek, S Rudin, C Ionita
PURPOSE: To create 4D parametric images using biplane Digital Subtraction Angiography (DSA) sequences co-registered with the 3D vascular geometry obtained from Cone Beam-CT (CBCT). METHODS: We investigated a method to derive multiple 4D Parametric Imaging (PI) maps using only one CBCT acquisition. During this procedure a 3D-DSA geometry is stored and used subsequently for all 4D images. Each time a biplane DSA is acquired, we calculate 2D parametric maps of Bolus Arrival Time (BAT), Mean Transit Time (MTT) and Time to Peak (TTP)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047800/we-de-207a-01-parallels-in-the-evolution-of-x-ray-angiographic-systems-and-devices-used-for-minimally-invasive-endovascular-therapy
#13
C Strother
: 1. Parallels in the evolution of x-ray angiographic systems and devices used for minimally invasive endovascular therapy Charles Strother - DSA, invented by Dr. Charles Mistretta at UW-Madison, was the technology which enabled the development of minimally invasive endovascular procedures. As DSA became widely available and the potential benefits for accessing the cerebral vasculature from an endovascular approach began to be apparent, industry began efforts to develop tools for use in these procedures...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047432/su-g-iep1-11-resting-state-fluctuation-of-bold-signal-amplitude-for-mapping-cerebrovascular-reactivity-in-presurgical-functional-mri
#14
P Wang, P Hou, S Kesler, R Colen, A Kumar, S Prabhu, H Liu
PURPOSE: Cerebrovascular reactivity (CVR) MRI with hypercapnia challenges, such as a breath-hold (BH) task, has been proposed to indicate areas with neurovascular uncoupling potentials for presurgical functional MRI (fMRI). This study aimed to explore the use of resting-state (RS) fMRI, in particular, the RS fluctuation of amplitude (RSFA) for detecting the impaired CVR and compare with BH MRI in patients with gliomas. METHODS: The BH and RS fMRI from six patients as part of their presurgical fMRI studies were analyzed...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047144/we-de-207a-02-advances-in-cone-beam-ct-anatomical-and-functional-imaging-in-angio-suite-to-enable-one-stop-shop-stroke-imaging-workflow
#15
G Chen
: 1. Parallels in the evolution of x-ray angiographic systems and devices used for minimally invasive endovascular therapy Charles Strother - DSA, invented by Dr. Charles Mistretta at UW-Madison, was the technology which enabled the development of minimally invasive endovascular procedures. As DSA became widely available and the potential benefits for accessing the cerebral vasculature from an endovascular approach began to be apparent, industry began efforts to develop tools for use in these procedures...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046575/tu-fg-209-02-effective-elimination-of-aliased-signal-using-an-apodized-aperture-pixel-design
#16
A Shankar, M Russ, S Vijayan, D Bednarek, S Rudin
PURPOSE: Signal and noise aliasing are major issues with high resolution direct and indirect detectors for which the Apodized Aperture Pixel (AAP) design provides an alternative solution. METHODS: High resolution detectors for neurovascular interventions have MTFs that remain significant even at the Nyquist frequency. Under-sampling in such detectors, leads to aliasing of object frequencies and noise. Frequencies above the Nyquist wrap into the lower frequency range leading to aliasing...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046482/we-de-207a-03-recent-advances-in-devices-used-in-neuro-interventions
#17
M Gounis
: 1. Parallels in the evolution of x-ray angiographic systems and devices used for minimally invasive endovascular therapy Charles Strother - DSA, invented by Dr. Charles Mistretta at UW-Madison, was the technology which enabled the development of minimally invasive endovascular procedures. As DSA became widely available and the potential benefits for accessing the cerebral vasculature from an endovascular approach began to be apparent, industry began efforts to develop tools for use in these procedures...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046297/su-f-e-21-change-in-retinal-arteriole-diameter-with-visual-simulation
#18
N Tellapragada, S Burns
PURPOSE: Neural activity and blood flow in the brain are tightly coupled. This coupling allows the brain to respond to periods of increased neural activity with increased blood flow. This coupling is known as neurovascular coupling. Many vascular based imaging techniques such as Functional MRI scans provide maps of signals of brain activity but they are limited by the resolution of fMRI to a few mm. The fMRI signal is indirect because the scanner is not tracking the neural activity directly but are measuring the changes in the blood oxygen levels...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28045346/utility-of-fusion-volumetric-images-from-computed-tomography-and-magnetic-resonance-imaging-for-localizing-the-mandibular-canal
#19
Chutamas Deepho, Hiroshi Watanabe, Shinya Kotaki, Junichiro Sakamoto, Yasunori Sumi, Tohru Kurabayashi
OBJECTIVES: The purpose of this study is to investigate whether computed tomography/magnetic resonance imaging (CT/MRI) fusion volumetric images can improve the detectability of the mandibular canal (MC) compared to CT alone. METHODS: Images of 31 lesions within or close to the mandible using both multi-slice CT (MSCT) and MRI were gathered from our imaging archives. All lesions underwent MSCT and three dimensional volumetric interpolated breath-hold examination (3D-VIBE) MRI...
January 3, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/28034477/percutane-image-guided-cryoablation-of-painful-osseous-metastases-a-retrospective-single-center-review
#20
Tatum A McArthur, Carl A Narducci, Phillip H Lander, Robert Lopez-Ben
PURPOSE: Painful osseous metastases are a common problem in patients with malignancy, and they can be associated with significant morbidity owing to immobility, pain, pathologic fracture, or neurovascular compromise or all of these. We retrospectively evaluated pain levels and tumor enhancement in patients who underwent palliative percutaneous cryoablation for painful bone metastasis. METHODS: In this institutional review board-approved, health insurance portability and accountability act-compliant study, we retrospectively searched our department׳s picture archiving system for patients who underwent computed tomography (CT)-guided percutaneous cryoablation for treatment of painful metastatic osseous disease over a 6-year period (1/1/2005-12/31/2011)...
November 10, 2016: Current Problems in Diagnostic Radiology
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