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Neurovascular imaging

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https://www.readbyqxmd.com/read/28549641/treatment-of-moyamoya-disease-and-unruptured-intracranial-aneurysm-in-floating-harbor-syndrome-a-case-report
#1
Daniel J Coughlin, Charles A Miller, A Jesse Schuette
BACKGROUND: This is the first report of the successful treatment of moyamoya disease (MMD) and an unruptured intracranial aneurysm in a patient with Floating-Harbor Syndrome (FHS). CASE DESCRIPTION: A 35 year-old, phenotypically syndromic woman presented with signs and symptoms consistent with ischemic stroke. MRI and catheter angiography confirmed diagnosis of moyamoya and a 6 mm basilar apex artery aneurysm (BAA). She underwent right sided craniotomy for direct and indirect revascularization by means of superficial temporal artery-middle cerebral artery (STA-MCA) bypass and encephalo-duro-arterio-synangiosis (EDAS)...
May 23, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28543843/white-matter-biomarkers-from-fast-protocols-using-axially-symmetric-diffusion-kurtosis-imaging
#2
Brian Hansen, Ahmad R Khan, Noam Shemesh, Torben E Lund, Ryan Sangill, Simon F Eskildsen, Leif Østergaard, Sune N Jespersen
White matter tract integrity (WMTI) can characterize brain microstructure in areas with highly aligned fiber bundles. Several WMTI biomarkers have now been validated against microscopy and provided promising results in studies of brain development and aging, as well as in a number of brain disorders. Currently, WMTI is mostly used in dedicated animal studies and clinical studies of slowly progressing diseases, and has not yet emerged as a routine clinical tool. To this end, a less data intensive experimental method would be beneficial by enabling high resolution validation studies, and ease clinical applications by speeding up data acquisition compared with typical diffusion kurtosis imaging (DKI) protocols utilized as part of WMTI imaging...
May 22, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28542809/arterial-spin-labeled-mr-imaging-detecting-biphasic-neurovascular-changes-in-migraine-with-persistent-aura
#3
Robert Burns, Maxine De Malherbe, Marie-Laure Chadenat, Fernando Pico, Dan Buch
No abstract text is available yet for this article.
May 19, 2017: Headache
https://www.readbyqxmd.com/read/28534706/analyses-of-thrombi-in-acute-ischemic-stroke-a-consensus-statement-on-current-knowledge-and-future-directions
#4
Simon F De Meyer, Tommy Andersson, Blaise Baxter, Martin Bendszus, Patrick Brouwer, Waleed Brinjikji, Bruce Cv Campbell, Vincent Costalat, Antoni Dávalos, Andrew Demchuk, Diederik Dippel, Jens Fiehler, Urs Fischer, Michael Gilvarry, Matthew J Gounis, Jan Gralla, Olav Jansen, Tudor Jovin, David Kallmes, Pooja Khatri, Kennedy R Lees, Elena López-Cancio, Charles Majoie, Henk Marquering, Ana Paula Narata, Raul Nogueira, Peter Ringleb, Adnan Siddiqui, István Szikora, David Vale, Rüdiger von Kummer, Albert J Yoo, Werner Hacke, David S Liebeskind
Limited data exist on clot composition and detailed characteristics of arterial thrombi associated with large vessel occlusion in acute ischemic stroke. Advances in endovascular thrombectomy and related imaging modalities have created a unique opportunity to analyze thrombi removed from cerebral arteries. Insights into thrombus composition, etiology, physical properties and neurovascular interactions may lead to future advancements in acute ischemic stroke treatment and improved clinical outcomes. Advances in imaging techniques may enhance clot characterization and inform therapeutic decision-making prior to treatment and reveal stroke etiology to guide secondary prevention...
January 1, 2017: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/28532919/image-guided-lateral-mass-osteotomy-for-en-bloc-resection-of-cervical-ewing-s-sarcoma-a-technical-note
#5
Julian Li, Kevin Phan, Tommy Manh Tran, Ralph Mobbs, Ralph Stanford
BACKGROUND: En bloc resection of Ewing's sarcoma according to Enneking's principles is technically challenging in the cervical spine due to the proximity of important neurovascular structures, complex local anatomy and biomechanical instability of radical resection. The rarity of Ewing's sarcoma and variability of presentation justifies ongoing compilation of the surgical nuances and subtleties of en bloc resection in the cervical spine. CASE DESCRIPTION: We present a 34-year-old male with Ewing's sarcoma of the neck who underwent successful en bloc resection using a novel technique of splitting the laminae and osteomising the lateral masses using image guidance...
May 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28526762/exacerbation-of-thromboinflammation-by-hyperglycemia-precipitates-cerebral-infarct-growth-and-hemorrhagic-transformation
#6
Jean-Philippe Desilles, Varouna Syvannarath, Véronique Ollivier, Clément Journé, Sandrine Delbosc, Célina Ducroux, William Boisseau, Liliane Louedec, Lucas Di Meglio, Stéphane Loyau, Martine Jandrot-Perrus, Louis Potier, Jean-Baptiste Michel, Mikael Mazighi, Benoit Ho-Tin-Noé
BACKGROUND AND PURPOSE: Admission hyperglycemia is associated with a poor outcome in acute ischemic stroke. How hyperglycemia impacts the pathophysiology of acute ischemic stroke remains largely unknown. We investigated how preexisting hyperglycemia increases ischemia/reperfusion cerebral injury. METHODS: Normoglycemic and streptozotocin-treated hyperglycemic rats were subjected to transient middle cerebral artery occlusion. Infarct growth and brain perfusion were assessed by magnetic resonance imaging...
May 19, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28525926/imaging-approaches-to-stroke-and-neurovascular-disease
#7
Seena Dehkharghani, Jalal Andre
No abstract text is available yet for this article.
June 1, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28521048/altered-coupling-between-resting-state-cerebral-blood-flow-and-functional-connectivity-in-schizophrenia
#8
Jiajia Zhu, Chuanjun Zhuo, Lixue Xu, Feng Liu, Wen Qin, Chunshui Yu
Background: Respective changes in resting-state cerebral blood flow (CBF) and functional connectivity in schizophrenia have been reported. However, their coupling alterations in schizophrenia remain largely unknown. Methods: 89 schizophrenia patients and 90 sex- and age-matched healthy controls underwent resting-state functional MRI to calculate functional connectivity strength (FCS) and arterial spin labeling imaging to compute CBF. The CBF-FCS coupling of the whole gray matter and the CBF/FCS ratio (the amount of blood supply per unit of connectivity strength) of each voxel were compared between the 2 groups...
May 17, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28520916/a-comparison-of-diffusion-weighted-imaging-abnormalities-following-balloon-remodeling-for-aneurysm-coil-embolization-in-the-ruptured-vs-unruptured-setting
#9
Stephen R Lowe, Tarun Bhalla, Holly Tillman, M Imran Chaudry, Aquilla S Turk, Raymond D Turner, Alejandro M Spiotta
BACKGROUND: The prothrombotic milieu seen in subarachnoid hemorrhage (SAH) poses a unique challenge to neurovascular surgeons with regard to device use and microcatheter practice. OBJECTIVE: To determine how demographic factors and balloon practices impact diffusion-weighted imaging (DWI) abnormalities and outcomes in patients with SAH compared to those without (non-SAH). METHODS: We retrospectively analyzed 77 patients with SAH treated by balloon-assisted coiling in a single institution compared with 81 consecutive patients with unruptured aneurysms treated by balloon-assisted coiling at the same institution...
May 17, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28516044/design-of-catheter-radio-frequency-coils-using-coaxial-transmission-line-resonators-for-interventional-neurovascular-mr-imaging
#10
Xiaoliang Zhang, Alastair Martin, Caroline Jordan, Prasheel Lillaney, Aaron Losey, Yong Pang, Jeffrey Hu, Mark Wilson, Daniel Cooke, Steven W Hetts
BACKGROUND: It is technically challenging to design compact yet sensitive miniature catheter radio frequency (RF) coils for endovascular interventional MR imaging. METHODS: In this work, a new design method for catheter RF coils is proposed based on the coaxial transmission line resonator (TLR) technique. Due to its distributed circuit, the TLR catheter coil does not need any lumped capacitors to support its resonance, which simplifies the practical design and construction and provides a straightforward technique for designing miniature catheter-mounted imaging coils that are appropriate for interventional neurovascular procedures...
April 2017: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/28515583/cavernous-sinus-melanoma-a-rare-tumor
#11
Shaileshkumar Garge, Sunithi Mani, Alfred Inbaraj, Vedantam Rajshekhar, Priyanka Mohapatra
Primay melanoma of the cavernous sinus is very rare with only few cases reported in the literature. We present the cross-sectional imaging findings of this rare tumor. The differential diagnosis for cavernous sinus mass lesion is wide as it contains vital neurovascular structures that may be affected by vascular, neoplastic, infective, and infiltrative lesions arising in the cavernous sinus proper or via extension from adjacent intra and/or extracranial regions. Radiologic imaging can narrow the differential diagnosis, however, imaging cannot definitely reach single diagnosis if they present in atypical form with hemorrage and cystic degeneration...
January 2017: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/28504673/a-fluoro-nissl-dye-identifies-pericytes-as-distinct-vascular-mural-cells-during-in-vivo-brain-imaging
#12
Eyiyemisi C Damisah, Robert A Hill, Lei Tong, Katie N Murray, Jaime Grutzendler
Pericytes and smooth muscle cells are integral components of the brain microvasculature. However, no techniques exist to unambiguously identify these cell types, greatly limiting their investigation in vivo. Here we show that the fluorescent Nissl dye NeuroTrace 500/525 labels brain pericytes with specificity, allowing high-resolution optical imaging in the live mouse. We demonstrate that capillary pericytes are a population of mural cells with distinct morphological, molecular and functional features that do not overlap with precapillary or arteriolar smooth muscle actin-expressing cells...
May 15, 2017: Nature Neuroscience
https://www.readbyqxmd.com/read/28504643/exploiting-neurovascular-coupling-a-bayesian-sequential-monte-carlo-approach-applied-to-simulated-eeg-fnirs-data
#13
Pierpaolo Croce, Filippo Zappasodi, Arcangelo Merla, Antonio Chiarelli
OBJECTIVE: Electrical and hemodynamic brain activity are linked through the neurovascular coupling process and they can be simultaneously measured through integration of Electroencephalography (EEG) and functional Near-Infrared Spectroscopy (fNIRS). Thanks to the lack of electro-optical interference, the two procedures can be easily combined and, whereas EEG provides electrophysiological information, fNIRS can provide measurements of two hemodynamic variables, such as oxygenated and deoxygenated hemoglobin...
May 15, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28503230/utility-of-preoperative-3-tesla-pelvic-phased-array-multiparametric-magnetic-resonance-imaging-in-prediction-of-extracapsular-extension-and-seminal-vesicle-invasion-of-prostate-cancer-and-its-impact-on-surgical-margin-status-experience-at-a-canadian-academic
#14
Taehyoung Lee, Jen Hoogenes, Ian Wright, Edward D Matsumoto, Bobby Shayegan
INTRODUCTION: To evaluate the utility of 3 Tesla (3T) pelvic phased-array (PPA) multiparametric magnetic resonance imaging (mpMRI) to predict extracapsular extension (ECE) and seminal vesicle invasion (SVI) and its subsequent effect on radical prostatectomy (RP) surgical margin status. METHODS: A retrospective evaluation was conducted of RP patients who underwent preoperative 3T PPA mpMRI (without endorectal coil) based on clinical probability of adverse pathological features...
May 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28502687/the-onodi-cell-an-anatomical-illustration
#15
Ali Tayebi Meybodi, Vera Vigo, Arnau Benet
This anatomical image demonstrates the sphenoethmoidal (Onodi) cell (a variant of the paranasal sinuses), the identification of which is critical to prevent neurovascular injury during endoscopic approaches to the sella and adjacent regions of the skull base.
May 11, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28493011/mri-of-thoracic-outlet-syndrome-in-children
#16
REVIEW
Govind B Chavhan, Vaishnavi Batmanabane, Prakash Muthusami, Alexander J Towbin, Gregory H Borschel
Thoracic outlet syndrome is caused by compression of the neurovascular bundle as it passes from the upper thorax to the axilla. The neurovascular bundle can be compressed by bony structures such as the first rib, cervical ribs or bone tubercles, or from soft-tissue abnormalities like a fibrous band, muscle hypertrophy or space-occupying lesion. Thoracic outlet syndrome commonly affects young adults but can be seen in the pediatric age group, especially in older children. Diagnosis is based on a holistic approach encompassing clinical features, physical examination findings including those triggered by various maneuvers, electromyography, nerve conduction studies and imaging...
May 10, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28492341/implications-of-neurovascular-uncoupling-in-functional-magnetic-resonance-imaging-fmri-of-brain-tumors
#17
Rebecca W Pak, Darian H Hadjiabadi, Janaka Senarathna, Shruti Agarwal, Nitish V Thakor, Jay J Pillai, Arvind P Pathak
Functional magnetic resonance imaging (fMRI) serves as a critical tool for presurgical mapping of eloquent cortex and changes in neurological function in patients diagnosed with brain tumors. However, the blood-oxygen-level-dependent (BOLD) contrast mechanism underlying fMRI assumes that neurovascular coupling remains intact during brain tumor progression, and that measured changes in cerebral blood flow (CBF) are correlated with neuronal function. Recent preclinical and clinical studies have demonstrated that even low-grade brain tumors can exhibit neurovascular uncoupling (NVU), which can confound interpretation of fMRI data...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28486051/characterization-of-differences-in-functional-connectivity-associated-with-close-range-blast-exposure
#18
Meghan Robinson, Dustin Clark, William Milberg, Regina McGlinchey, David Salat
Despite the prevalence of blast injuries in recent overseas conflicts, our knowledge of their impact on neural health is lacking. We have recently published work demonstrating differences in functional magnetic resonance imaging (fMRI) connectivity that were specific to close-range blast exposure (CBE), as opposed to other prevalent military-related factors. Here, we replicate this finding in an independent sample of 135 Veterans, again finding that CBE, regardless of concussion, is predictive of persistent changes in brain physiology...
May 9, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28484963/blood-brain-barrier-protection-as-a-therapeutic-strategy-for-acute-ischemic-stroke
#19
Ali Ehsan Sifat, Bhuvaneshwar Vaidya, Thomas J Abbruscato
The blood-brain barrier (BBB) is a vital component of the neurovascular unit (NVU) containing tight junctional (TJ) proteins and different ion and nutrient transporters which maintain normal brain physiology. BBB disruption is a major pathological hallmark in the course of ischemic stroke which is regulated by the actions of different factors working at different stages of cerebral ischemia including matrix metalloproteinases (MMPs), inflammatory modulators, vesicular trafficking, oxidative pathways, and junctional-cytoskeletal interactions...
May 8, 2017: AAPS Journal
https://www.readbyqxmd.com/read/28481804/computed-tomography-in-the-diagnosis-of-classical-trigeminal-neuralgia
#20
Victor A Baliazin, Elena V Baliazina, Daniil P Aksenov
OBJECTIVE: This study aims to characterize the pathogenesis of neurovascular conflict in trigeminal neuralgia (TN) with the goal of producing a reliable diagnostic method. METHODS: Data were obtained during microvascular decompression surgery. The normal relationship between the superior cerebellar artery (SCA) and the trigeminal nerve root also was characterized in postmortem cases. Furthermore, SCA was imaged with high-resolution computed tomography angiography...
May 6, 2017: Journal of Computer Assisted Tomography
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