keyword
MENU ▼
Read by QxMD icon Read
search

Neurovascular imaging

keyword
https://www.readbyqxmd.com/read/29782006/neurovascular-network-explorer-2-0-a-simple-tool-for-exploring-and-sharing-a-database-of-optogenetically-evoked-vasomotion-in-mouse-cortex-in-vivo
#1
Hana Uhlirova, Peifang Tian, Kıvılcım Kılıç, Martin Thunemann, Vishnu B Sridhar, Radim Chmelik, Hauke Bartsch, Anders M Dale, Anna Devor, Payam A Saisan
The importance of sharing experimental data in neuroscience grows with the amount and complexity of data acquired and various techniques used to obtain and process these data. However, the majority of experimental data, especially from individual studies of regular-sized laboratories never reach wider research community. A graphical user interface (GUI) engine called Neurovascular Network Explorer 2.0 (NNE 2.0) has been created as a tool for simple and low-cost sharing and exploring of vascular imaging data...
May 4, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29773951/the-role-of-neuroinflammation-and-neurovascular-dysfunction-in-major-depressive-disorder
#2
REVIEW
Sang Won Jeon, Yong-Ku Kim
Although depression has generally been explained with monoamine theory, it is far more multifactorial, and therapies that address the disease's pathway have not been developed. In this context, an understanding of neuroinflammation and neurovascular dysfunction would enable a more comprehensive approach to depression. Inflammation is in a sense a type of allostatic load involving the immune, endocrine, and nervous systems. Neuroinflammation is involved in the pathophysiology of depression by increasing proinflammatory cytokines, activating the hypothalamus-pituitary-adrenal axis, increasing glucocorticoid resistance, and affecting serotonin synthesis and metabolism, neuronal apoptosis and neurogenesis, and neuroplasticity...
2018: Journal of Inflammation Research
https://www.readbyqxmd.com/read/29770594/functional-optical-coherence-tomography-of-neurovascular-coupling-interactions-in-the-retina
#3
Taeyoon Son, Minhaj Alam, Devrim Toslak, Benquan Wang, Yiming Lu, Xincheng Yao
Quantitative evaluation of retinal neurovascular coupling is essential for a better understanding of visual function and early detection of eye diseases. However, there is no established method to monitor coherent interactions between stimulus-evoked neural activity and hemodynamic responses at high resolution. Here we report a multi-modal functional optical coherence tomography (OCT) imaging methodology to enable concurrent intrinsic optical signal (IOS) imaging of stimulus-evoked neural activity and hemodynamic responses at capillary resolution...
May 16, 2018: Journal of Biophotonics
https://www.readbyqxmd.com/read/29765820/a-comparative-analysis-of-endoscopic-assisted-transoral-and-transnasal-approaches-to-parapharyngeal-space-a-cadaveric-study
#4
Xicai Sun, Bo Yan, Huy Q Truong, Hamid Borghei-Razavi, Carl H Snyderman, Juan C Fernandez-Miranda
Background  Surgical resection of parapharyngeal space (PPS) tumors is very challenging. An endoscopic-assisted surgical approach to this region requires detailed and precise anatomic knowledge. The main purpose of this study is to describe and compare the detailed anatomy of the PPS via transnasal transpterygoid (TP) and endoscopic-assisted transoral (TO) approaches. Materials and Methods  Six fresh injected cadaver heads (12 sides) were prepared for dissection of the PPS via TP and TO approaches. Computed tomography (CT) with image-based navigation (Navigation System II; Stryker, Kalamazoo, Michigan, United States) was used to identify bony structures around the PPS...
June 2018: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/29763986/early-iv-injected-human-dermis-derived-mesenchymal-stem-cells-after-transient-global-cerebral-ischemia-do-not-pass-through-damaged-blood-brain-barrier
#5
Ji Hyeon Ahn, Bai Hui Chen, Joon Ha Park, Bich Na Shin, Tae-Kyeong Lee, Jeong Hwi Cho, Jae Chul Lee, Jeong-Ran Park, Se-Ran Yang, Sungwoo Ryoo, Myoung Cheol Shin, Jun Hwi Cho, Il Jun Kang, Choong Hyun Lee, In Koo Hwang, Young-Myeong Kim, Moo-Ho Won
There is lack of researches on effects of intravenously injected mesenchymal stem cells (MSCs) against transient cerebral ischemia (TCI). We investigated the disruption of the neurovascular unit (NVU), which comprises the blood-brain barrier (BBB) and examined entry of human dermis-derived MSCs (hDMSCs) into the damaged hippocampal CA1 area in a gerbil model of TCI, and their subsequent effects on neuroprotection and cognitive function. Impairments of neurons, and BBB were examined by immunohistochemistry, electron microscopy, and Evans blue and immunoglobulin G (IgG) leakage...
May 15, 2018: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/29757059/quantitative-hemodynamic-analysis-of-cerebral-blood-flow-and-neurovascular-coupling-using-optical-coherence-tomography-angiography
#6
Paul Shin, WooJhon Choi, JongYoon Joo, Wang-Yuhl Oh
Functional hyperemia in the rat cortex was investigated using high-speed optical coherence tomography (OCT) angiography and Doppler OCT. OCT angiography (OCTA) was performed to image the hemodynamic stimulus-response over a wide field of view. Temporal changes in vessel diameters in different vessel compartments, which were determined as the diameters of erythrocyte flows in OCT angiograms, were measured in order to monitor localized hemodynamic changes. Our results showed that the dilation of arterioles at the site of activation was accompanied by the dilation of upstream arteries...
January 1, 2018: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/29748039/comparing-panoramic-radiographs-and-cone-beam-computed-tomography-impact-on-radiographic-features-and-differential-diagnoses
#7
Li Zhen Lim, Ricardo J Padilla, Glenn J Reside, Donald A Tyndall
OBJECTIVES: The aims of this study were to determine whether lesion features appear differently on panoramic radiography (PAN) and cone beam computed tomography (CBCT), and whether the use of CBCT affects diagnostic accuracy and observers' confidence in comparison with PAN. STUDY DESIGN: Three oral and maxillofacial radiologists reviewed 33 sets of PAN images and CBCT images of biopsy-proven lesions. They described 12 different lesion features and provided up to 3 ranked differential diagnoses, as well as their confidence with respect to those diagnoses...
April 17, 2018: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/29739912/early-cerebral-vein-after-endovascular-ischemic-stroke-treatment-predicts-symptomatic-reperfusion-hemorrhage
#8
Samuel C D Cartmell, Robyn L Ball, Rajani Kaimal, Nicholas A Telischak, Michael P Marks, Huy M Do, Robert L Dodd, Gregory W Albers, Maarten G Lansberg, Jeremy J Heit
BACKGROUND AND PURPOSE: Parenchymal hemorrhage (PH) after endovascular mechanical thrombectomy in acute ischemic stroke leads to worse outcomes. Better clinical and imaging biomarkers of symptomatic reperfusion PH are needed to identify patients at risk. We identified clinical and imaging predictors of reperfusion PH after endovascular mechanical thrombectomy with attention to early cerebral veins (ECVs) on postreperfusion digital subtraction angiography. METHODS: We performed a retrospective cohort study of consecutive acute ischemic stroke patients undergoing endovascular mechanical thrombectomy at our neurovascular referral center...
May 8, 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29732436/the-c7-pedicle-as-a-superior-fixation-point-in-spinal-stabilization-for-spinal-metastatic-disease
#9
Harjot Thind, Andrew J Fabiano
Spinal metastatic disease (SMD) often requires spinal stabilization; however, the cervicothoracic junction can be a challenging area to instrument. An anterior approach may require division of the sternum. A posterior or posterolateral approach may rely on cervical lateral mass screws for superior construct fixation that are more prone to pullout than screws placed in a pedicle. The C7 pedicle is able to support pedicle screw fixation in most instances based on morphological features of the vertebra. When the C7 pedicle is used as a superior fixation point, it aligns with the thoracic pedicles below to create a streamlined posterior construct...
March 2018: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29731281/three-dimensional-angioarchitecture-and-microsurgical-treatment-of-arteriovenous-fistulas-at-the-craniocervical-junction
#10
So Fujimoto, Keisuke Takai, Hirofumi Nakatomi, Taichi Kin, Nobuhito Saito
Digital subtraction angiography (DSA) is the gold standard for diagnosing vascular malformations; however, difficulties are associated with visualizing the angioarchitecture of arteriovenous fistulas at the craniocervical junction (CCJ AVFs) using DSA because of their complex regional neurovascular anatomy. The present study evaluated the application of 3-dimensional computer graphics (3D CG) to the surgical planning of CCJ AVFs. Six patients with CCJ AVFs who underwent microsurgery and/or endovascular treatment were included...
May 3, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29727868/arthroscopic-treatment-of-diffuse-pigmented-villonodular-synovitis-of-the-knee-complete-synovectomy-and-septum-removal-midterm-results
#11
Sohrab Keyhani, Seyyed Morteza Kazemi, Jin Hwan Ahn, René Verdonk, Mehran Soleymanha
The purpose of this study was to evaluate and describe the clinical results of complete arthroscopic synovectomy through the four arthroscopic portals in the knees affected by diffuse pigmented villonodular synovitis (DPVNS). Between 2009 and 2012, 21 patients (15 men and 6 women) with the diffuse form of PVNS of the knee were enrolled in the study after qualification. The clinical diagnosis was confirmed by magnetic resonance imaging and postsurgical pathologic examination. All patients underwent complete synovectomy through posteromedial, posterolateral, anteromedial, and anterolateral portals...
May 4, 2018: Journal of Knee Surgery
https://www.readbyqxmd.com/read/29722296/reconstruction-of-difference-rod-imaging-for-cone-beam-ct-neuro-angiography
#12
Pengwei Wu, Joseph Webster Stayman, Michael Mow, Wojciech Zbijewski, Alejandro Sisniega, Nafi Aygun, Robert Stevens, David H Foos, Xiaohui Wang, Jeffrey H Siewerdsen
Timely evaluation of neurovasculature via CT angiography (CTA) is critical to detection of pathology such as ischemic stroke. Cone-beam CTA (CBCT-A) systems provide potential advantages in timely use at the point-of-care, although challenges of a relatively slow gantry rotation speed introduce tradeoffs among image quality, data consistency, and data sparsity. This work describes and evaluates a new reconstruction-of-difference (RoD) approach that is robust to such challenges.
 Methods: A fast digital simulation framework was developed to test the performance of RoD over standard reference reconstruction methods like filtered back-projection (FBP) and penalized likelihood (PL) over a broad range of imaging conditions, grouped into three scenarios to test the trade-off between data consistency, data sparsity and peak contrast...
May 3, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29719553/47-consecutive-cases-of-pipeline-flex-flow-diversion-utilizing-a-novel-large-bore-intracranial-intermediate-catheter-nuances-and-institutional-experience-with-the-syphontrak
#13
Li-Mei Lin, Bowen Jiang, Matthew T Bender, Erick M Westbroek, Jessica K Campos, Rafael J Tamargo, Judy Huang, Alexander L Coon, Geoffrey P Colby
Background: The increasing complexity of modern neurointerventions has necessitated a shift in intracranial access techniques towards more robust distal support platforms. Here we present our experience with the Syphontrak Support Catheter (Codman Neuro, Raynham, MA, USA) in the triaxial platform for the implantation of the second-generation Pipeline Flex embolization device (PED Flex; Medtronic Neurovascular, Irvine, CA, USA). Methods: We retrospectively identified patients who underwent PED Flex treatment utilizing the Syphontrak at a single institution...
April 2018: Interventional Neurology
https://www.readbyqxmd.com/read/29710516/investigation-of-ginkgo-biloba-extract-egb-761-promotes-neurovascular-restoration-and-axonal-remodeling-after-embolic-stroke-in-rat-using-magnetic-resonance-imaging-and-histopathological-analysis
#14
Man-Zhong Li, Yi Zhang, Hai-Yan Zou, Jun-Yao Ouyang, Yu Zhan, Le Yang, Brian Chi-Yan Cheng, Lei Wang, Qiu-Xia Zhang, Jian-Feng Lei, Yuan-Yuan Zhao, Hui Zhao
EGb 761 is a standardized natural extract from Ginkgo biloba leaf that has shown neuroprotective effects after ischemic stroke. This study aimed to use magnetic resonance imaging (MRI) to noninvasively evaluate whether EGb 761 promotes neurovascular restoration and axonal remodeling in a rat model of focal cerebral ischemia. Male Sprague-Dawley rats were subjected to permanent right middle cerebral artery occlusion (MCAO) and treated with EGb 761 (60 mg/kg) or saline intragastrically once daily for 15 days starting 6 h after MCAO...
April 24, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29706581/cortical-circuit-activity-evokes-rapid-astrocyte-calcium-signals-on-a-similar-timescale-to-neurons
#15
Jillian L Stobart, Kim David Ferrari, Matthew J P Barrett, Chaim Glück, Michael J Stobart, Marc Zuend, Bruno Weber
Sensory stimulation evokes intracellular calcium signals in astrocytes; however, the timing of these signals is disputed. Here, we used novel combinations of genetically encoded calcium indicators for concurrent two-photon imaging of cortical astrocytes and neurons in awake mice during whisker deflection. We identified calcium responses in both astrocyte processes and endfeet that rapidly followed neuronal events (∼120 ms after). These fast astrocyte responses were largely independent of IP3 R2-mediated signaling and known neuromodulator activity (acetylcholine, serotonin, and norepinephrine), suggesting that they are evoked by local synaptic activity...
April 20, 2018: Neuron
https://www.readbyqxmd.com/read/29705020/imaging-of-hemifacial-spasm
#16
M Hermier
Almost all primary hemifacial spasms are associated with one or more neurovascular conflicts, most often at the root exit zone in the immediate vicinity of the brainstem. Imaging has first to exclude a secondary hemifacial spasm and secondly to search for and characterize the responsible neurovascular conflict(s). Magnetic resonance imaging should include high-resolution anatomical hyper T2-weighted sequences and magnetic resonance angiography by using 1.5 or even better 3 Tesla magnets. The most frequent vascular compressions are from the anterior-inferior cerebellar artery, the posterior-inferior cerebellar artery and the vertebrobasilar artery; venous conflicts are very rare...
April 25, 2018: Neuro-Chirurgie
https://www.readbyqxmd.com/read/29685630/symptomatic-medulla-compression-by-vertebral-artery
#17
Leszek Lombarski, Przemysław Kunert, Marcin Skawiński, Marek Prokopienko, Zbigniew Lewandowski, Andrzej Marchel
OBJECTIVE: Vertebral artery medulla compression syndrome (VAMCS) is a very rare condition manifesting as different neurological focal deficits. The case of a 36-year-old male with symptomatic brainstem compression by vertebral artery (VA) treated by means of microvascular decompression (MVD) and a review of the literature is presented. CASE REPORT: On admission, a 36-year-old patient presented with hypoalgesia, hypothermesthesia and hemiparesis on the left side...
March 17, 2018: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/29681886/importance-of-collateralization-in-patients-with-large-artery-intracranial-occlusive-disease-long-term-longitudinal-assessment-of-cerebral-hemodynamic-function
#18
Larissa McKetton, Lakshmikumar Venkatraghavan, Julien Poublanc, Olivia Sobczyk, Adrian P Crawley, Casey Rosen, Frank L Silver, James Duffin, Joseph A Fisher, David J Mikulis
Patients with large artery intracranial occlusive disease (LAICOD) are at risk for both acute ischemia and chronic hypoperfusion. Collateral circulation plays an important role in prognosis, and imaging plays an essential role in diagnosis, treatment planning, and prognosis of patients with LAICOD. In addition to standard structural imaging, assessment of cerebral hemodynamic function is important to determine the adequacy of collateral supply. Among the currently available methods of assessment of cerebral hemodynamic function, measurement of cerebrovascular reactivity (CVR) using blood oxygen level-dependent (BOLD) MRI and precisely controlled CO2 has shown to be a safe, reliable, reproducible, and clinically useful method for long-term assessment of patients...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29680848/changes-in-dimension-of-neurovascular-canals-in-the-mandible-and-maxilla-a-radiographic-finding-in-patients-diagnosed-with-mronj
#19
D Goller-Bulut, G Özcan, F Avci
BACKGROUND: The aim of this retrospective study was to compare the morphological features of neurovascular canals and foramina of patients with medication-related osteonecrosis of the jaws (MRONJ) and healthy individuals by using cone beam computed tomography (CBCT). MATERIAL AND METHODS: The CBCT images of 58 patients under bisphosphonate therapy diagnosed with MRONJ and age gender- matched controls were retrospectively evaluated. The diameter of mandibular and nasopalatine canal and mandibular, mental and lingual foramina were measured on several sections of CBCT...
May 1, 2018: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/29679616/early-detection-of-diabetic-retinopathy
#20
REVIEW
Hamid Safi, Sare Safi, Ali Hafezi-Moghadam, Hamid Ahmadieh
Diabetic retinopathy (DR) is a primary cause of visual impairment worldwide. Diabetes mellitus may be associated with ophthalmoscopically nonvisible neurovascular damage that progresses before the first clinical signs of DR appear. Reduction of the inner neuroretinal layer thickness on macular optical coherence tomography (OCT), reduced contrast sensitivity primarily at low spatial frequencies, abnormal results in color vision and microperimetry tests, and a prolonged implicit time recorded by multifocal electroretinography have been proposed for detection of early functional and nonvisible structural neuroretinal changes...
April 18, 2018: Survey of Ophthalmology
keyword
keyword
105348
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"