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Marc Sorel, Naaman Zrek, Blanche Locko, Catherine Armessen, Samar S Ayache, Jean-Pascal Lefaucheur
OBJECTIVE: To evaluate the changes in glutamate/GABA balance of intracortical excitability produced by ketamine, delivered at subanaesthetic dose to treat patients with complex regional pain syndrome (CRPS). METHODS: In 19 patients with CRPS, we assessed the effect of a 5-day ketamine protocol on various clinical aspects, including pain and depression, and on cortical excitability parameters provided by transcranial magnetic stimulation testing. RESULTS: The rest motor threshold (RMT) and the amplitude of the motor evoked potentials at 120% of RMT were not modified after ketamine therapy...
March 8, 2018: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
Mana Biabani, Michael Farrell, Maryam Zoghi, Gary Egan, Shapour Jaberzadeh
Transcranial magnetic stimulation (TMS)-induced motor evoked potentials (MEPs) are frequently used to assess corticospinal and intercortical activities. Trial to trial variance of the potentials is commonly observed, and averages of multiple MEPs are usually reported. Multiple trials have resources implications and are not compatible with some experimental protocols. This study investigated the minimum number of MEPs required to reliably assess corticospinal excitability (CSE), short interval intracortical inhibition (SICI) and intercortical facilitation (ICF), within and between sessions...
March 15, 2018: Neuroscience Letters
Gabriele Gäbler, Michaela Coenen, Deborah Lycett, Tanja Stamm
BACKGROUND: High quality, continuity and safe interdisciplinary healthcare is essential. Nutrition and dietetics plays an important part within the interdisciplinary team in many health conditions. In order to work more effectively as an interdisciplinary team, a common terminology is needed. This study investigates which categories of the ICF-Dietetics are used in clinical dietetic care records in Austria and which are most relevant to shared language in different medical areas. METHOD: A national multicenter retrospective study was conducted to collect clinical dietetic care documentation reports...
March 3, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
Paula Nahuelhual, Carolina Giaconi, M Alejandra Machuca
INTRODUCTION: According to the International Classification of Functioning, Disability and Health (ICF), participation is defined as "the involvement of the subject in situations of life" and is fun damental in the development of children and adolescents. In case of children with disabilities, participation allows a better understanding of the possible impact of deficiencies in daily life. OBJECTIVE: To evaluate measurement scales of participation in children and adolescents with and without disabilities...
December 2017: Revista Chilena de Pediatría
Mark Yulis, Miguel Quiros, Roland Hilgarth, Charles A Parkos, Asma Nusrat
Desmosomal cadherins mediate intercellular adhesion and have also been shown to regulate homeostatic signaling in epithelial cells. We have previously reported that select pro-inflammatory cytokines induce Dsg2 ectodomain cleavage and shedding from intestinal epithelial cells (IECs). Dsg2 extracellular cleaved fragments (Dsg2 ECF) function to induce paracrine pro-proliferative signaling in epithelial cells. In this study, we show that exposure of IECs to pro-inflammatory cytokines interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α) resulted in Dsg2 intracellular cleavage and generation of a ~55 kDa fragment (Dsg2 ICF)...
March 9, 2018: Cell Death & Disease
Marcus Schiltenwolf
Medicolegal assessments of claimants with chronic muskuloskeletal pain conditions are frequent. The first German guideline published in 2005 for the medicolegal assessment of claimants in chronic pain is now available in its 4th version (AWMF register number 094 - 003). It gives recommendations for the procedure and serves to ensure the quality of expert opinions when complaints about chronic pain are the leading symptom. In the current version, the indications for ordering medical assessments in pain syndromes have been reformulated, the assessment criteria have been adapted to ICF specifications, and an unequivocal distinction has been introduced between questions of state and causal assessment...
March 9, 2018: Zeitschrift Für Orthopädie und Unfallchirurgie
Jonas Verbrugghe, Els Knippenberg, Steven Palmaers, Thomas Matheve, Wout Smeets, Peter Feys, Annemie Spooren, Annick Timmermans
INTRODUCTION: Musculoskeletal disorders (MSDs) are a burden on the healthcare system. Exercise therapy is an important part of MSD rehabilitation. Motion detection systems are developed to support exercise therapy settings. This systematic review aims 1) to investigate which types of motion detection systems have been used as a technological support for exercise therapy, 2) to investigate the characteristics of motion detection supported exercise therapy in relation to its clinical indications, and 3) to evaluate the effectiveness of motion detection supported exercise therapy, in MSD rehabilitation...
March 7, 2018: European Journal of Physical and Rehabilitation Medicine
Szilvia Geyh, Urban Schwegler, Claudio Peter, Rachel Müller
PURPOSE: To discuss the representation and organization of information describing persons' lived experience of health from a personal factors perspective in the light of the International Classification of Functioning, Disability and Health, using spinal cord injury as a case in point for disability. METHODS: The scientific literature was reviewed, discussion rounds conducted, and qualitative secondary analyses of data carried out using an iterative inductive-deductive approach...
March 6, 2018: Disability and Rehabilitation
Alberto Zaragoza, Jorge Espinosa, Regina Ramos, Jose Antonio Cobos, Juan Luis Aragones, Carlos Vega, Eduardo Sanz, Jorge Ramirez, Chantal Valeriani
We investigate with computer simulations the effect of applying an electric field on the water-to-ice transition. We use a combination of state-of-the-art simulation techniques to obtain phase boundaries and crystal growth rates (direct coexistence), nucleation
 rates (seeding) and interfacial free energies (seeding and mold integration). 
 First, we consider ice Ih, the most stable polymorph in the absence of a field. Its normal melting temperature, speed of crystal 
 growth and nucleation rate (for a given supercooling) diminish as the intensity of the field goes up...
March 6, 2018: Journal of Physics. Condensed Matter: An Institute of Physics Journal
Dragana Pavlović, Marija Pavlović, Dragan Čakmak, Olga Kostić, Snežana Jarić, Sanja Sakan, Dragana Đorđević, Miroslava Mitrović, Ivan Gržetić, Pavle Pavlović
The main soil properties, concentrations of selected elements (As, Cd, Cr, Cu, Fe, Mn, Ni, Pb, and Zn), and the chemical speciation of each element were determined in urban soil samples taken from urban parks in four Serbian cities (Belgrade, Pančevo, Obrenovac, and Smederevo) exposed to different sources of pollution. Pollution indices (PI, PIN ) and factors (MF, ICF, GCF) also were evaluated. The study revealed As and Cd concentrations below the detection limit, whereas the content of Cr, Cu, Fe, Mn, Ni, Pb, and Zn at some sites exceeded the limits established by local regulations, as well as the background values, which may represent an environmental threat...
March 5, 2018: Archives of Environmental Contamination and Toxicology
Markku Paanalahti, Guna Berzina, Åsa Lundgren-Nilsson, Toni Arndt, Katharina S Sunnerhagen
PURPOSE: To examine if the International Classification of Functioning (ICF) core set for stoke contains problems that are relevant for the persons living with stroke as expressed in the Stroke Impact Scale (SIS). METHODS: Cross-sectional study of 242 persons with previous stroke. The agreement between the perceived problems in the SIS items and problems in the categories of Comprehensive ICF Core Set for stroke were analyzed using percent of agreement and Kappa statistic...
March 5, 2018: Disability and Rehabilitation
Raquel Cantero-Téllez, Nancy Naughton, Lori Algar, Kristin Valdes
STUDY DESIGN: Systematic review. INTRODUCTION: Mirror therapy is a treatment used to address hand function following a stroke. Measurement of outcomes using appropriate assessment tools is crucial; however, many assessment options exist. PURPOSE OF THE STUDY: The purpose of this study is to systematically review outcome measures that are used to assess hand function following mirror therapy after stroke and, in addition, to identify the psychometric and descriptive properties of the included measures and through the linking process determine if the outcome measures are representative of the International Classification of Functioning, Disability and Health (ICF)...
February 28, 2018: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
Sharon V Thompson, Donna J Cech, Susan M Cahill, Joseph J Krzak
PURPOSE: The purpose of the current study was to examine how comprehensively the Pediatric Evaluation of Disability Inventory-Computer Adaptive Test (PEDI-CAT) addresses Activity and Participation components of the International Classification of Functioning, Disability, and Health (ICF). METHODS: Two raters individually linked the 276 items of the PEDI-CAT to the ICF using ICF linking rules, the PEDI-CAT manual, and the ICF browser. Agreement between reviewers was evaluated, and reliability of the linking process was assessed using Cohen's κ...
March 1, 2018: Pediatric Physical Therapy
Sally Scott-Roberts, Catherine Purcell
Purpose of Review: This phenomenological study explored the lived experience of six adults with developmental coordination disorder (DCD) and its potential impact on functional mobility. Utilising the International Classification of Functioning (World Health Organisation, 2001), the data derived from interviews were analysed to consider how persistent motor impairments impact on activity engagement and participation. Recent Findings: Much of the research evidence pertaining to DCD focuses on children...
2018: Current Developmental Disorders Reports
Fary Khan, Bhasker Amatya, Wouter de Groote, Mayowa Owolabi, Ilyas M Syed, Abderrazak Hajjoui, Muhammad N Babur, Tahir M Sayed, Yvonne Frizzell, Amaramalar S Naicker, Maryam Fourtassi, Alaeldin Elmalik, Mary P Galea
OBJECTIVE: Despite the prevalence of disability in low-and middle-income countries, the clinical skills of the rehabilitation workforce are not well described. We report health professionals' perspectives on clinical skills in austere settings and identify context-specific gaps in workforce capacity. METHODS: A cross-sectional pilot survey (Pakistan, Morocco, Nigeria, Malaysia) of health professionals' working in rehabilitation in hospital and community settings...
February 28, 2018: Journal of Rehabilitation Medicine
A Duvignaud, A Fianu, A Bertolotti, J Jaubert, A Michault, P Poubeau, A Fred, M Méchain, B-A Gaüzère, F Favier, D Malvy, P Gérardin
Prolonged fatigue is increasingly reported among chikungunya virus (CHIKV)-infected populations. We investigated the relationships between CHIKV exposure, long-lasting rheumatic musculoskeletal pain (LRMSP) and chronic fatigue. 1094 participants (512 CHIKV seropositive and 582 seronegative) of the TELECHIK population-based cohort were analysed considering the duration of the manifestations throughout an average 2-year follow-up. Weighted prevalence rates and prevalence ratios for LRMSP, idiopathic chronic fatigue (ICF), and chronic fatigue syndrome (CFS)-like illness, both latter syndromes adapted from Centers for Disease Control (CDC)-1994/Fukuda criteria, were compared...
February 28, 2018: Epidemiology and Infection
Karin R Grarup, Nele Devoogdt, Liv Inger Strand
PURPOSE: To translate and culturally adapt the Lymphoedema Functioning, Disability and Health Questionnaire (Lymph-ICF) for breast cancer survivors with arm lymphedema into Danish and examine its content validity and reliability. METHODS: (1) Translation and cultural adaptation was performed in 10 steps following international guidelines (International Society for Pharmacoeconomics and Outcome Research); (2) cognitive interviewing (step 7) was conducted in 15 women with breast cancer related arm lymphedema to explore understandability, interpretation, and cultural relevance; (3) after adjustments, content validity (N = 52) was explored by interviews; and (4) reliability (N = 50) examined by intraclass correlation coefficients (ICC) statistics and Cronbach alpha analysis...
February 27, 2018: Physiotherapy Theory and Practice
Philippe Vignaud, Marine Mondino, Emmanuel Poulet, Ulrich Palm, Jérôme Brunelin
Recent studies have shown heterogeneous results regarding the influence of intensity and duration of motor transcranial direct current stimulation (tDCS) on cortical excitability. In this pilot crossover study including 14 healthy participants, we compared the effects of a single session of anodal-tDCS set with two commonly used durations (20 and 30minutes) and intensities (1 and 2mA) on short-interval intracortical inhibition (SICI) and intracortical facilitation (ICF). Regardless of the current intensity, 20minutes of tDCS increased SICI (3ms inter-stimulus interval ISI) and decreased ICF (7ms ISI); 30minutes of tDCS did not affect cortical excitability...
February 23, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
Raquel Bouça-Machado, Walter Maetzler, Joaquim J Ferreira
Although yet poorly defined and often misused, the concept of functional mobility has been used in research studies as a more global and ecological outcome of patients' health status. Functional mobility is a person's physiological ability to move independently and safely in a variety of environments in order to accomplish functional activities or tasks and to participate in the activities of daily living, at home, work and in the community. Parkinson's disease (PD) has a direct impact on patients' motor control and on mobility in general...
2018: Journal of Parkinson's Disease
Charlene M T Robertson, Shannon M DeForge, Cara F Dosman
Objectives: To determine the domains of parent-therapist collaboratively set goals for intervention within a family-centered, tertiary-level early developmental intervention (EDI) program. To report changes in ratings for performance and satisfaction of performance pre- and postintervention for the set goals. Methods: This study includes all children with complex developmental disabilities (30 ± 3 months of age, 61% boys) registered in a tertiary-level EDI program from 2009 to 2012 whose parents completed the Canadian Occupational Performance Measure (COPM) to evaluate goal setting...
July 2017: Paediatrics & Child Health
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