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https://www.readbyqxmd.com/read/29143994/intermittent-compressive-force-induces-human-mandibular-derived-osteoblast-differentiation-via-wnt-%C3%AE-catenin-signaling
#1
Pimrumpai Rochanakit Sindhavajiva, Panunn Sastravaha, Mansuang Arksornnukit, Prasit Pavasant
Mechanical force induces an efflux of ATP that regulates osteoblast differentiation. However, the effect of mechanical force-induced ATP efflux on WNT/β-catenin signaling remains unclarified. The aim of this study was to investigate the effect of intermittent compressive force (ICF) and ICF-induced extracellular ATP on osteoblast differentiation via WNT/β-catenin signaling in human mandibular-derived osteoblast precursors (hMOBPs). The hMOBPs were subjected to ICF (1.5 g/cm(2) , 0.3 Hz) for 20 h. To investigate the role of ATP, Apyrase (0...
November 16, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/29143954/-why-dutch-mental-health-care-practitioners-should-have-second-thoughts-about-adopting-the-english-cluster-model
#2
T G Broekman, G M Schippers
Administrators and policymakers in the Netherlands have concluded, after considerable deliberation, that the existing Dutch diagnosis-related group (drg)-based system of diagnosis treatment combinations for funding mental health care should be replaced by the so-called English model. The details, however, need to be analysed very carefully by Dutch professional health care practitioners.<br/> AIM: To make the reader aware of the reasons why the English model should not be adopted in the Netherlands.<br/> METHOD: We describe and analyse the English cluster model and the referral instrument (the Honos, supplemented by six items) and we demonstrate how it is applied in England...
2017: Tijdschrift Voor Psychiatrie
https://www.readbyqxmd.com/read/29130767/using-the-international-classification-of-functioning-disability-and-health-to-identify-outcome-domains-for-a-core-outcome-set-for-aphasia-a-comparison-of-stakeholder-perspectives
#3
Sarah J Wallace, Linda Worrall, Tanya Rose, Guylaine Le Dorze
PURPOSE: This study synthesised the findings of three separate consensus processes exploring the perspectives of key stakeholder groups about important aphasia treatment outcomes. This process was conducted to generate recommendations for outcome domains to be included in a core outcome set for aphasia treatment trials. MATERIALS AND METHODS: International Classification of Functioning, Disability, and Health codes were examined to identify where the groups of: (1) people with aphasia, (2) family members, (3) aphasia researchers, and (4) aphasia clinicians/managers, demonstrated congruence in their perspectives regarding important treatment outcomes...
November 12, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29127528/changes-in-volume-and-incidence-of-lymphedema-during-and-after-treatment-with-docetaxel-doxorubicin-and-cyclophosphamide-tac-in-patients-with-breast-cancer
#4
Janine T Hidding, Carien H G Beurskens, Philip J van der Wees, Wilmy C A M Bos, Maria W G Nijhuis-van der Sanden, Hanneke W M van Laarhoven
PURPOSES: The purposes of this study were to investigate the incidence of lymphedema in patients with breast cancer during and after adjuvant treatment with docetaxel, doxorubicin, and cyclophosphamide (TAC), to identify predictors for development of lymphedema, and to describe consequences in daily life in relation to lymphedema. METHODS: This is a prospective study with measurements before chemotherapy (T0), during chemotherapy before cycle 2 (T1), cycle 4 (T2), and 1 month after completion of treatment (T3)...
November 10, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29124112/concise-informed-consent-to-increase-data-and-biospecimen-access-may-accelerate-innovative-alzheimer-s-disease-treatments
#5
REVIEW
Ann M Hake, Penny A Dacks, Stephen P Arnerić
Introduction: Informed consent forms that restrict the distribution of data and samples have been an impediment to advancing Alzheimer's disease (AD) understandings and treatments. The Coalition Against Major Disease public-private partnership developed concise addenda to responsibly broaden data access of informed consent forms. Methods: Coalition Against Major Disease members identified key elements for ensuring data and biospecimen access, and patient privacy protection according to applicable US law...
November 2017: Alzheimer's & Dementia: Translational Research & Clinical Interventions
https://www.readbyqxmd.com/read/29107042/measuring-participation-after-stroke-in-africa-development-of-the-participation-measurement-scale
#6
Oyéné Kossi, Félix Nindorera, Charles Sèbiyo Batcho, Thierry Adoukonou, Massimo Penta, Jean-Louis Thonnard
OBJECTIVE: To develop a valid stroke-specific tool for the measurement of participation in Africa, named the Participation Measurement Scale (PM-Scale). DESIGN: Observational study and questionnaire development. SETTING: Outpatient Rehabilitation centers. PARTICIPANTS: Stroke patients (N = 276); mean age ± standard deviation of 58.5 ± 11.1 years; 57% male. INTERVENTION: Not applicable. MAIN OUTCOME MEASURES: Participants completed a 100-item experimental questionnaire of the PM-Scale...
October 26, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29101845/motor-cortex-excitability-in-seizure-free-stx1b-mutation-carriers-with-a-history-of-epilepsy-and-febrile-seizures
#7
Maria-Ioanna Stefanou, Debora Desideri, Justus Marquetand, Paolo Belardinelli, Christoph Zrenner, Holger Lerche, Ulf Ziemann
OBJECTIVE: Mutations in STX1B encoding the presynaptic protein syntaxin-1B are associated with febrile seizures with or without epilepsy. It is unclear to what extent these mutations are linked to abnormalities of cortical glutamatergic or GABAergic neurotransmission. We explored this question using single- and paired-pulse transcranial magnetic stimulation (TMS) excitability markers. METHODS: We studied nine currently asymptomatic adult STX1B mutation carriers with history of epilepsy and febrile seizures, who had been seizure-free for at least eight years without antiepileptic drug treatment, and ten healthy age-matched controls...
October 20, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29096266/mobile-assessment-of-the-lower-limb-kinematics-in-healthy-persons-and-in-persons-with-degenerative-knee-disorders-a-systematic-review
#8
REVIEW
R van der Straaten, L De Baets, I Jonkers, A Timmermans
Inertial sensor systems are increasingly used in the assessment of persons with knee osteoarthritis (KOA) and total knee replacement (TKR). This systematic review aims to (1) investigate the application of inertial sensor systems and kinematics derived from these systems, and (2) assess if current assessment protocols consist of tasks which are, according to the International Classification of Functioning, Disability and Health (ICF) for KOA, relevant for persons with KOA and TKR. A search was conducted in six electronic databases (ACM, CINAHL, EMBASE, IEEE, PubMed, Web of Science) to include papers assessing the knee and one or more adjacent joints by means of inertial sensors in healthy persons or persons with KOA or TKR...
October 5, 2017: Gait & Posture
https://www.readbyqxmd.com/read/29096214/reduced-motor-cortical-inhibition-in-migraine-a-blinded-transcranial-magnetic-stimulation-study
#9
J P Neverdahl, P M Omland, M Uglem, M Engstrøm, T Sand
OBJECTIVE: To investigate motor cortical excitability, inhibition, and facilitation with navigated transcranial magnetic stimulation (TMS) in migraine in a blinded cross-sectional study. METHODS: Resting motor threshold (RMT), cortical silent period (CSP), short-interval intracortical inhibition (SICI), and intracortical facilitation (ICF) were compared in 27 interictal migraineurs and 33 controls. 24 female interictal migraineurs and 27 female controls were compared in subgroup analyses...
September 22, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29091515/factors-associated-with-the-setting-of-function-related-goals-among-community-dwelling-older-people
#10
Juliana S Oliveira, Leanne Hassett, Catherine Sherrington, Elisabeth Ramsay, Catherine Kirkham, Shona Manning, Anne Tiedemann
This study aimed to summarise the function-related goals set by older people and to explore gender differences in goal selection, and associations between balance-related goals and fall history, self-rated balance and fear of falling. We included community-dwelling people aged 60+ participating in two randomised controlled trials. Participants nominated two function-related goals, which were summarised into components of the International Classification of Functioning, Disability and Health (ICF). Chi-square analyses were used to explore associations between goal types and participant characteristics...
November 1, 2017: Journal of Aging and Physical Activity
https://www.readbyqxmd.com/read/29089004/knee-stability-and-movement-coordination-impairments-knee-ligament-sprain-revision-2017
#11
David S Logerstedt, David Scalzitti, May Arna Risberg, Lars Engebretsen, Kate E Webster, Julian Feller, Lynn Snyder-Mackler, Michael J Axe, Christine M McDonough
The Orthopaedic Section of the American Physical Therapy Association (APTA) has an ongoing effort to create evidence-based practice guidelines for orthopaedic physical therapy management of patients with musculoskeletal impairments described in the World Health Organization's International Classification of Functioning, Disability, and Health (ICF). The purpose of these revised clinical practice guidelines is to review recent peer-reviewed literature and make recommendations related to knee ligament sprain...
November 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29083441/measuring-active-and-healthy-ageing-applying-a-generic-interdisciplinary-assessment-model-incorporating-icf
#12
P Stute, N Bitterlich, J Bousquet, F Meissner, M von Wolff, D Poethig
OBJECTIVES: In this study we compared the chronological and bio-functional age between two German speaking cohorts 30 years apart applying a comprehensive and generic Active and Healthy Aging (AHA) assessment model incorporating ICF. METHODS: Single-centre, cross-sectional, observational, non-interventional, non-randomized trial at an University based women's hospital, division of Gynecological Endocrinology and Reproductive Medicine. All participants followed a standardized, holistic battery of biopsychosocial assessments consisting of bio-functional status (BFS), bio-functional age (BFA) and additional validated psychometric questionnaires...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29074112/identifying-content-gaps-in-health-status-measures-for-intermittent-claudication-using-the-international-classification-of-functioning-disability-and-health
#13
David S Kauvar, Candice L Osborne
OBJECTIVE: The Walking Impairment Questionnaire (WIQ) and Intermittent Claudication Questionnaire (ICQ) are commonly used patient-reported functional outcome measures for intermittent claudication, but their functional representation has not been characterized. The World Health Organization's International Classification of Functioning, Disability and Health (ICF) framework comprehensively describes health-related function and has been used to evaluate health status and quality of life (QOL) measures...
October 23, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29063793/the-participation-pyramid-a-response-to-reconsideration-icf-scheme-by-heerkens-et%C3%A2-al-2017
#14
Johan Borg
No abstract text is available yet for this article.
October 24, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29059120/change-in-depression-confidence-and-physical-function-among-older-adults-with-mild-cognitive-impairment
#15
Jennifer L Ellis, Peter Altenburger, Yvonne Lu
BACKGROUND AND PURPOSE: Nearly a quarter of those in the United States older than 71 years experience mild cognitive impairment. Persons with mild cognitive impairment battle depression and progressive disengagement from daily activities, which contribute to participation restriction and activity limitation. Daily engagement in meaningful activity (DEMA) is a tailored intervention designed to benefit persons with mild cognitive impairment and their caregivers through preserved engagement and supported adjustment to cognitive changes...
October 20, 2017: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/29057988/the-meaning-of-work-after-spinal-cord-injury-a-scoping-review
#16
REVIEW
Mohammad Mosayed Ullah, Ellie Fossey, Rwth Stuckey
STUDY DESIGN: Scoping review. OBJECTIVES: To explore the meaning of work after spinal cord injury (SCI) in existing literature. METHODS: Arksey and O'Malley's widely used methodological framework for scoping reviews was used to guide this review. Studies involving adults with SCI, conducted using qualitative methods, and published in peer reviewed literature were identified based on key terms and searches in three databases (CINAHL, MEDLINE, PsycINFO)...
October 23, 2017: Spinal Cord
https://www.readbyqxmd.com/read/29053439/factors-influencing-indonesian-women-s-use-of-maternal-health-care-services
#17
Anna Kurniati, Ching-Min Chen, Ferry Efendi, Sarni Maniar Berliana
Employing the 2012 Indonesia Demographic and Health Survey data, we aimed to examine factors influencing married women to use maternity services. Data of married women who had given birth in the last five years before the survey were included in the analysis (n = 14,672). Factors of education, employment, women's age at first marriage, age at first birth, spousal education difference, contraceptive use, place of residence, and woman's attitude toward wife beating were associated with the use of antenatal care, institutional delivery, and postnatal care services...
October 20, 2017: Health Care for Women International
https://www.readbyqxmd.com/read/29047670/polarization-smoothing-for-single-beam-by-a-nematic-liquid-crystal-scrambler
#18
Yuancheng Wang, Fang Wang, Ying Zhang, Xiaoxia Huang, Dongxia Hu, Wanguo Zheng, Rihong Zhu, Xuewei Deng
Polarization smoothing (PS) is a key approach to suppress laser plasma instabilities (LPI) in inertial confinement fusion (ICF) experiments. Here, we propose a liquid crystal (LC) PS element to realize single beam smoothing and demonstrate its smoothing effect, in principle, with a 2×2 LC polarization checkerboard, which reduces the laser intensity variation in the focal spot to 78.4%. LC PS elements, which have potential applications in high-power ICF laser drivers, have many advantages because they are easy to fabricate, cost effective, flexible, and large...
October 10, 2017: Applied Optics
https://www.readbyqxmd.com/read/29041820/applying-the-icf-linking-rules-to-compare-population-based-data-from-different-sources-an-exemplary-analysis-of-tools-used-to-collect-information-on-disability
#19
Lenildo de Moura, Wederson Rufino Dos Santos, Shamyr Sulyvan de Castro, Elizabeth Ito, Danilo Campos da Luz E Silva, Renata Tiene de Carvalho Yokota, Zohra Abaakouk, Heleno Rodrigues Corrêa Filho, Marco Antonio Gomes Pérez, Carolina Saskia Fellinghauer, Carla Sabariego
BACKGROUND: Data on disability are regularly collected by different institutions or ministries using specific tools for different purposes, for instance to estimate the prevalence of disability or eligibility of specific populations for social benefits. The interoperability of disability data collected in countries is essential for policy making and to monitor the implementation of the Convention on the Rights of Persons with Disabilities. The first objective of this paper is to map and compare tools that collect data on disability for different purposes, more specifically the Brazilian National Health Survey and the Brazilian Functioning Index to the World Health Organization (WHO) and the World Bank Model Disability Survey (MDS), currently recommended as a standard tool for disability measurement...
October 17, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29040940/risk-assessment-and-chemical-fractionation-of-selected-elements-in-surface-sediments-from-lake-qarun-egypt-using-modified-bcr-technique
#20
Naglaa F Soliman, Gehan M El Zokm, Mohamed A Okbah
In this study, spatial distribution and chemical fractionation were conducted to appraise the overall classification of Al, B, Cd, Cr, and Pb as well as their ecological risks in Lake Qarun sediments. Also, the other chemical components (CaCO3, TOC, SO4(2-), SiO3(2-), PO4(3-), F, Ca, and Mg) that represented the chemical composition of the sediments were determined. Modified BCR sequential extraction technique was used to evaluate the four (acid soluble, reducible, oxidizable and residual) fractions of the surface sediments...
October 9, 2017: Chemosphere
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