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Socket healing

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https://www.readbyqxmd.com/read/28643933/oncologic-doses-of-zoledronic-acid-induce-site-specific-suppression-of-bone-modelling-in-rice-rats
#1
C R Exposto, U Oz, J S Callard, M J Allen, H Khurana, A D' Atri, X Mo, S A Fernandez, D N Tatakis, K Edmonds, P M Westgate, S S Huja
OBJECTIVES: To examine the effect of zoledronic acid (ZOL) on cortical bone modelling and healing of extraction sockets in the jaw bones of a rodent model. We hypothesized ZOL suppresses both the bone formation in the modelling mode in the jaw bones and alters the extraction site healing. MATERIAL & METHODS: Rice rats were administered saline solution and two dose regimens of ZOL: 0.1 mg/kg, twice a week, for 4 weeks (n=17, saline=8 & ZOL=9) and a higher dose of 0...
June 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/28611844/immediate-loading-of-single-implants-in-the-anterior-maxilla-a-1-year-prospective-clinical-study-on-34-patients
#2
Miguel Stanley, Filipa Calheiros Braga, Beatriz Mota Jordao
PURPOSE: To present the outcomes of immediately loaded single implants placed in the anterior maxilla. METHODS: Over a 2-year period, all patients referred to a private clinic were considered for enrolment in this study. Inclusion criteria were single-tooth placement in postextraction sockets or healed sites of the anterior maxilla. All implants were immediately loaded and followed for a period of 1 year after the placement of definitive crowns. The outcome measures were implant stability, survival, and success...
2017: International Journal of Dentistry
https://www.readbyqxmd.com/read/28587096/the-effect-of-platelet-rich-fibrin-calcium-sulfate-hemihydrate-platelet-rich-plasma-and-resorbable-collagen-on-soft-tissue-closure-of-extraction-sites
#3
Lisa M Yerke, Amal Jamjoom, Talal M Zahid, Robert E Cohen
Rapid and complete soft tissue healing after tooth extraction minimizes surgical complications and facilitates subsequent implant placement. We used four treatment methods and assessed changes in soft tissue socket closure following tooth extraction in humans. The effects of platelet-rich fibrin-calcium sulfate hemihydrate (PRF-CSH), platelet-rich plasma-calcium sulfate hemihydrate (PRP-CSH), a resorbable collagen dressing (RCD), and no grafting material were compared in a randomized, controlled pilot study with a blinded parallel design (N = 23)...
May 25, 2017: Journal of Functional Biomaterials
https://www.readbyqxmd.com/read/28577573/differences-in-placement-of-calcium-phosphate-hybridized-tendon-grafts-within-the-femoral-bone-tunnel-during-acl-reconstruction-do-not-influence-tendon-to-bone-healing
#4
Hirotaka Mutsuzaki, Hiromi Nakajima, Shunsuke Nomura, Masataka Sakane
BACKGROUND: Calcium phosphate (CaP)-hybridization of tendon grafts has been shown to improve tendon-to-bone healing. The purpose of this study was to clarify the influence of different tendon graft placement methods on tendon-to-bone healing using CaP-hybridized tendon grafts in anterior cruciate ligament (ACL) reconstructions in rabbits. METHODS: We compared two methods of tendon graft placement within the femoral bone tunnel: suspension of the tendon graft within the bone tunnel (suspension group) and implantation of the tendon graft coherent with the bone socket (coherence group)...
June 2, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28577053/regenerative-properties-of-collagenated-porcine-bone-grafts-in-human-maxilla-demonstrative-study-of-the-kinetics-by-synchrotron-radiation-microtomography-and-light-microscopy
#5
Alessandra Giuliani, Giovanna Iezzi, Serena Mazzoni, Adriano Piattelli, Vittoria Perrotti, Antonio Barone
OBJECTIVES: Recently, it has been reported that heterologous biomaterials, where the collagen matrix is preserved, seem to facilitate blood clotting and the subsequent invasion of repairing and regenerative cells. This study aimed at evaluating the healing of human extraction sockets grafted with a collagenated cortico-cancellous porcine bone (mp3®, OsteoBiol®, Tecnoss®, Giaveno, Italy) by synchrotron radiation X-ray microtomography (microCT) and histology in order to have a 3D quantitative characterization over time...
June 2, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28541269/immediate-loading-of-tantalum-based-implants-in-fresh-extraction-sockets-in-patient-with-sjogren-syndrome-a-case-report-and-literature-review
#6
Cristian Peron, Fawad Javed, Georgios E Romanos
PURPOSE: The objective of this article is to demonstrate treatment of a clinical case using implants in conjunction with immediate loading in a patient with Sjogren syndrome (SS) and to present the current status of knowledge about this type of patients with dental implants. MATERIALS AND METHODS: This article describes a 62-year-old woman patient with SS and partially edentulous maxilla who was rehabilitated with 5 immediately loaded tantalum-based dental implants (TBDIs) placed in fresh extraction sockets...
May 22, 2017: Implant Dentistry
https://www.readbyqxmd.com/read/28529150/preventive-effect-of-phosphodiesterase-inhibitor-pentoxifylline-against-medication-related-osteonecrosis-of-the-jaw-an-animal-study
#7
Gül Merve Yalcin-Ulker, Alev Cumbul, Gonca Duygu-Capar, Ünal Uslu, Kemal Sencift
PURPOSE: The aim of this experimental study was to investigate the prophylactic effect of pentoxifylline (PTX) on medication-related osteonecrosis of the jaw (MRONJ). MATERIALS AND METHODS: Female Sprague-Dawley rats (n = 33) received zoledronic acid (ZA) for 8 weeks to create an osteonecrosis model. The left mandibular second molars were extracted and the recovery period lasted 8 weeks before sacrifice. PTX was intraperitoneally administered to prevent MRONJ...
April 26, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28523312/an-evaluation-of-a-collagen-based-material-osseointegration
#8
Horia Octavian Manolea, Monica Mihaela CrăiŢoiu, LaurenŢiu Mogoantă, Ionela Teodora Dascălu, Alina Iren Moraru, Doriana Agop Forna, Răzvan MercuŢ
The aim of this study is to evaluate the osseointegration of a collagen-based material Alveoprotect, suitable for socket preservations, while preserving the vestibular bone lamella. This material is intended to be used in the field of implantology for smaller bone defects. Thus, 3-mm diameter experimental cavities were carried out on the calvaria and maxilla of 18 laboratory Wistar rats. The cavities were augmented with the collagen fleece Alveoprotect or left unaugmented as a control group and half of the laboratory animals were sacrificed after two months, and the other half after four months in order to evaluate in vivo the way in which the inserted material is osseointegrated...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28511517/holistic-healing-through-herbs-effectiveness-of-aloe-vera-on-post-extraction-socket-healing
#9
Vijaya Lakshmi Nimma, Harsha Vardhan Talla, Jaya Krishna Bairi, Madhulatha Gopaldas, Haritha Bathula, Sandeep Vangdoth
INTRODUCTION: Advances in the field of alternative medicine has encouraged the use of various natural products for multiple uses in the field of dentistry for treatment of various oral diseases. A natural herbal product is Aloe vera, which has number of benefits with no reported side effects and gaining considerable importance in clinical research. AIM: The aim of this cross-sectional randomized interventional study was to evaluate the effectiveness of Aloe vera in the healing of post extraction sockets...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28508515/extra-oral-digital-scanning-and-imaging-superimposition-for-volume-analysis-of-bone-remodeling-after-tooth-extraction-with-and-without-2-types-of-particulate-porcine-mineral-insertion-a-randomized-controlled-trial
#10
Antonio Barone, Paolo Toti, Giovan-Battista Menchini-Fabris, Giacomo Derchi, Simone Marconcini, Ugo Covani
BACKGROUND: Incorporation of bone substitute material into the extraction socket could minimize the edentulous ridge volume loss or maximize the bone formation within the healing area. PURPOSE: The aim of the study was to test the effectiveness in maintaining the volumetric contour of fresh extraction sockets grafted with or without 2 types of porcine biomaterials and covered with a resorbable barrier. MATERIALS AND METHODS: In the present multi-center single-blind randomized control trial, 55 patients underwent 1-tooth extraction, were surveyed, and randomly allocated to control- (25 sites, nat-group) or test groups (15 sites grafted with pre-hydrated collagenated cortico-cancellous porcine bone, coll-group, and 15 with cortical porcine bone, cort-group)...
May 16, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28492757/meloxicam-as-a-radiation-protective-agent-on-mandibles-of-irradiated-rats
#11
Mayra Cristina Yamasaki, Yuri Nejaim Gina Delia Roque-Torres, Deborah Queiroz Freitas
This study evaluated the action of ionizing radiation and the possible radioprotective effect of the non-steroidal anti-inflammatory drug meloxicam on the bone physiology of rat mandibles by assessing the alveolar socket healing and bone strength. Forty male Wistar rats were divided in 4 groups (n=10): control (CG), irradiated (IG), meloxicam (MG), meloxicam irradiated (MIG). A dose of 0.2 mg/kg meloxicam was administered to MG and MIG. After this, IG and MIG were irradiated with 15 Gy radiation dose in the mandible...
March 2017: Brazilian Dental Journal
https://www.readbyqxmd.com/read/28478869/immediate-implant-placement-into-fresh-extraction-sockets-versus-delayed-implants-into-healed-sockets-a-systematic-review-and-meta-analysis
#12
REVIEW
C C Mello, C A A Lemos, F R Verri, D M Dos Santos, M C Goiato, E P Pellizzer
The aim of this systematic review and meta-analysis was to compare the survival rate of the implants and the peri-implant tissue changes associated with implants inserted in fresh extraction sockets and those inserted in healed sockets. This review has been registered at PROSPERO under the number CRD42016043309. A systematic search was conducted by two reviewers independently in the databases PubMed/MEDLINE, Embase, and the Cochrane Library using different search terms; articles published until November 2016 were searched for...
May 3, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28438860/bone-regeneration-of-hydroxyapatite-with-granular-form-or-porous-scaffold-in-canine-alveolar-sockets
#13
Seok Jin Jang, Se Eun Kim, Tae Sung Han, Jun Sik Son, Seong Soo Kang, Seok Hwa Choi
This study was undertaken to assess bone regeneration using hydroxyapatite (HA). The primary focus was comparison of bone regeneration between granular HA (gHA) forms and porous HA (pHA) scaffold. The extracted canine alveolar sockets were divided with three groups: control, gHA and pHA. Osteogenic effect in the gHA and pHA groups showed bone-specific surface and bone mineral density to be significantly higher than that of the control group (p<0.01). Bone volume fraction, bone mineral density, and amount of connective tissue related to disturbing osseointegration of the gHA group was higher than in the pHA group...
May 2017: In Vivo
https://www.readbyqxmd.com/read/28428609/socket-preservation
#14
L Fee
Socket preservation maintains bone volume post-extraction in anticipation of an implant placement or fixed partial denture pontic site. This procedure helps compensate for the resorption of the facial bone wall. Socket preservation should be considered when implant placement needs to be delayed for patient or site-related reasons. The ideal healing time before implant placement is six months. Socket preservation can reduce the need for later bone augmentation. By reducing bone resorption and accelerating bone formation it increases implant success and survival...
April 21, 2017: British Dental Journal
https://www.readbyqxmd.com/read/28422326/alveolar-ridge-dimensional-changes-following-ridge-preservation-procedure-with-novel-devices-part-3-histological-analysis-in-non-human-primate-model
#15
Yingying Su, Jianxia Tang, Seiko Min, Lijia Guo, Yitong Liu, Yilin Xie, Jimin Xiong, Songlin Wang, Mauricio G Araújo, Homayoun H Zadeh, Yi Liu
OBJECTIVES: This study sought to investigate the histological changes following tooth extraction, ridge preservation and augmentation, using novel devices designed to obturate the oral orifice of extraction sockets (SocketKAP™) and provide structural support for sockets with defective bony walls (SocketKAGE™) in a non-human primate model. MATERIAL AND METHODS: Six Macaca fascicularis were imaged by cone beam computed tomography to register their preoperative alveolar bone...
April 19, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/28390826/estimation-of-date-of-death-through-wound-healing-of-an-extraction-socket-a-case-report
#16
Joan Viciano, Ruggero D'Anastasio, Cristian D'Ovidio, Sara Costantini, Aldo Carnevale, Luigi Capasso
Surgical extraction of teeth due to dental pathologies is a relatively common procedure in modern man. The healing of the wound that results occurs in gradual and sequential stages, such that the analysis of this repair process can be very useful in forensic investigations on human remains. The following study reports on a particular case where the remodeling of a tooth socket allowed an estimation of the time that had elapsed from the day of the surgical extraction of the tooth to the time of death. The corpse was that of a woman of 34 years...
March 27, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28384521/rna-isolation-from-alveolar-bone-and-gene-expression-analysis-of-rank-rankl-and-opg-a-new-tool-to-monitor-bone-remodeling-and-healing-in-different-bone-substitutes-used-for-prosthetic-rehabilitation
#17
Elena Canciani, Claudia Dellavia, Monica Gioia Marazzi, Davide Augusti, Daniela Carmagnola, Elena Vianello, Luigi Canullo, Emanuela Galliera
OBJECTIVE: (i) To validate a simple and efficient method for extracting high quality RNA from small samples of bone tissue, (ii) to test its application on limited amounts of grafted oral bone and (iii) to analyze the gene expression of the OPG/RANK/RANKL system and IL-6 in "spontaneous healing" and grafted tissue. DESIGN: 26 patients in need of extraction of one lower molar tooth were divided in 3 groups. In group A (8 patients) the alveolar socket was left for spontaneous healing, in group B (8 patients) it was filled with a hydroxyapatite scaffold while in group C (10 patients) it was filled with hydroxyapatite granules...
August 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28356687/evaluation-of-two-socket-healing-procedures-with-and-without-mesenchymal-stem-cells-a-comparative-study
#18
Abhinav Jain, Mahinder Singh, K P Ganapathy, Vikas Ramola, Deepak Passi, Komal Jain
AIMS AND OBJECTIVES: Successful preservation of the edentulous ridge after extraction may eliminate or reduce the need for ridge augmentation procedures. It is proved that grafting of fresh extraction sockets with bone grafts promotes ridge preservation. An objective method of maintaining height and width of alveolar ridge using mesenchymal stem cells (MSCs) seeded on collagen membrane was implemented in this study. METHODOLOGY: Ten bilaterally symmetrical extraction sockets scheduled for extraction were selected for this study...
July 2016: National Journal of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28356684/effects-of-honey-in-the-management-of-alveolar-osteitis-a-study
#19
Nikita Soni, Vibha Singh, Shadab Mohammad, R K Singh, U S Pal, Ranjana Singh, Jyatasana Aggrwal, Mahesh Pal
INTRODUCTION: Alveolar osteitis (AO) is a complication of tooth extraction which indicates inflammation of alveolar bone of either maxilla or mandible. This study uses Apitherapy where honey catalyses biological reactions to improve immune system, makes local environment unbearable for microorganisms in the affected socket and enhances healing. MATERIALS AND METHODS: 50 patients of AO were included in the study. After cleansing of the affected socket, honey dressing was applied...
July 2016: National Journal of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28348611/can-tert-butylhydroquinone-improve-the-healing-of-extracted-tooth-socket-in-rats
#20
Somayeh Khoramian Tusi, Tahereh Eslam Manesh, Mahmood Sheikh Fathollahi, Ali Bagherian
BACKGROUND: Tooth extraction causes an open wound in the soft and hard tissues. During the inflammatory phase of the healing process, a large amount of free radicals are produced and cause oxidative stress, which leads to tissue damage and delayed wound healing. Thus, in this study, we evaluated the effect of tert-butylhydroquinone (TBHQ), as an antioxidant, on the healing process of tooth sockets in rats. MATERIALS AND METHODS: To conduct this experimental study, male Wistar rats (n = 42) were divided into two groups...
January 2017: Dental Research Journal
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