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https://www.readbyqxmd.com/read/28529150/preventive-effect-of-phosphodiesterase-inhibitor-pentoxifylline-against-medication-related-osteonecrosis-of-the-jaw-an-animal-study
#1
Gül Merve Yalcin-Ulker, Alev Cumbul, Gonca Duygu-Capar, Ünal Uslu, Kemal Sencift
PURPOSE: The aim of this experimental study was to investigate the prophylactic effect of pentoxifylline (PTX) on medication-related osteonecrosis of the jaw (MRONJ). MATERIALS AND METHODS: Female Sprague-Dawley rats (n = 33) received zoledronic acid (ZA) for 8 weeks to create an osteonecrosis model. The left mandibular second molars were extracted and the recovery period lasted 8 weeks before sacrifice. PTX was intraperitoneally administered to prevent MRONJ...
April 26, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28523312/an-evaluation-of-a-collagen-based-material-osseointegration
#2
Horia Octavian Manolea, Monica Mihaela CrăiŢoiu, LaurenŢiu Mogoantă, Ionela Teodora Dascălu, Alina Iren Moraru, Doriana Agop Forna, Răzvan MercuŢ
The aim of this study is to evaluate the osseointegration of a collagen-based material Alveoprotect, suitable for socket preservations, while preserving the vestibular bone lamella. This material is intended to be used in the field of implantology for smaller bone defects. Thus, 3-mm diameter experimental cavities were carried out on the calvaria and maxilla of 18 laboratory Wistar rats. The cavities were augmented with the collagen fleece Alveoprotect or left unaugmented as a control group and half of the laboratory animals were sacrificed after two months, and the other half after four months in order to evaluate in vivo the way in which the inserted material is osseointegrated...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28511517/holistic-healing-through-herbs-effectiveness-of-aloe-vera-on-post-extraction-socket-healing
#3
Vijaya Lakshmi Nimma, Harsha Vardhan Talla, Jaya Krishna Bairi, Madhulatha Gopaldas, Haritha Bathula, Sandeep Vangdoth
INTRODUCTION: Advances in the field of alternative medicine has encouraged the use of various natural products for multiple uses in the field of dentistry for treatment of various oral diseases. A natural herbal product is Aloe vera, which has number of benefits with no reported side effects and gaining considerable importance in clinical research. AIM: The aim of this cross-sectional randomized interventional study was to evaluate the effectiveness of Aloe vera in the healing of post extraction sockets...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28508515/extra-oral-digital-scanning-and-imaging-superimposition-for-volume-analysis-of-bone-remodeling-after-tooth-extraction-with-and-without-2-types-of-particulate-porcine-mineral-insertion-a-randomized-controlled-trial
#4
Antonio Barone, Paolo Toti, Giovan-Battista Menchini-Fabris, Giacomo Derchi, Simone Marconcini, Ugo Covani
BACKGROUND: Incorporation of bone substitute material into the extraction socket could minimize the edentulous ridge volume loss or maximize the bone formation within the healing area. PURPOSE: The aim of the study was to test the effectiveness in maintaining the volumetric contour of fresh extraction sockets grafted with or without 2 types of porcine biomaterials and covered with a resorbable barrier. MATERIALS AND METHODS: In the present multi-center single-blind randomized control trial, 55 patients underwent 1-tooth extraction, were surveyed, and randomly allocated to control- (25 sites, nat-group) or test groups (15 sites grafted with pre-hydrated collagenated cortico-cancellous porcine bone, coll-group, and 15 with cortical porcine bone, cort-group)...
May 16, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28492757/meloxicam-as-a-radiation-protective-agent-on-mandibles-of-irradiated-rats
#5
Mayra Cristina Yamasaki, Yuri Nejaim Gina Delia Roque-Torres, Deborah Queiroz Freitas
This study evaluated the action of ionizing radiation and the possible radioprotective effect of the non-steroidal anti-inflammatory drug meloxicam on the bone physiology of rat mandibles by assessing the alveolar socket healing and bone strength. Forty male Wistar rats were divided in 4 groups (n=10): control (CG), irradiated (IG), meloxicam (MG), meloxicam irradiated (MIG). A dose of 0.2 mg/kg meloxicam was administered to MG and MIG. After this, IG and MIG were irradiated with 15 Gy radiation dose in the mandible...
March 2017: Brazilian Dental Journal
https://www.readbyqxmd.com/read/28478869/immediate-implant-placement-into-fresh-extraction-sockets-versus-delayed-implants-into-healed-sockets-a-systematic-review-and-meta-analysis
#6
REVIEW
C C Mello, C A A Lemos, F R Verri, D M Dos Santos, M C Goiato, E P Pellizzer
The aim of this systematic review and meta-analysis was to compare the survival rate of the implants and the peri-implant tissue changes associated with implants inserted in fresh extraction sockets and those inserted in healed sockets. This review has been registered at PROSPERO under the number CRD42016043309. A systematic search was conducted by two reviewers independently in the databases PubMed/MEDLINE, Embase, and the Cochrane Library using different search terms; articles published until November 2016 were searched for...
May 3, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28438860/bone-regeneration-of-hydroxyapatite-with-granular-form-or-porous-scaffold-in-canine-alveolar-sockets
#7
Seok Jin Jang, Se Eun Kim, Tae Sung Han, Jun Sik Son, Seong Soo Kang, Seok Hwa Choi
This study was undertaken to assess bone regeneration using hydroxyapatite (HA). The primary focus was comparison of bone regeneration between granular HA (gHA) forms and porous HA (pHA) scaffold. The extracted canine alveolar sockets were divided with three groups: control, gHA and pHA. Osteogenic effect in the gHA and pHA groups showed bone-specific surface and bone mineral density to be significantly higher than that of the control group (p<0.01). Bone volume fraction, bone mineral density, and amount of connective tissue related to disturbing osseointegration of the gHA group was higher than in the pHA group...
May 2017: In Vivo
https://www.readbyqxmd.com/read/28428609/socket-preservation
#8
L Fee
Socket preservation maintains bone volume post-extraction in anticipation of an implant placement or fixed partial denture pontic site. This procedure helps compensate for the resorption of the facial bone wall. Socket preservation should be considered when implant placement needs to be delayed for patient or site-related reasons. The ideal healing time before implant placement is six months. Socket preservation can reduce the need for later bone augmentation. By reducing bone resorption and accelerating bone formation it increases implant success and survival...
April 21, 2017: British Dental Journal
https://www.readbyqxmd.com/read/28422326/alveolar-ridge-dimensional-changes-following-ridge-preservation-procedure-with-novel-devices-part-3-histological-analysis-in-non-human-primate-model
#9
Yingying Su, Jianxia Tang, Seiko Min, Lijia Guo, Yitong Liu, Yilin Xie, Jimin Xiong, Songlin Wang, Mauricio G Araújo, Homayoun H Zadeh, Yi Liu
OBJECTIVES: This study sought to investigate the histological changes following tooth extraction, ridge preservation and augmentation, using novel devices designed to obturate the oral orifice of extraction sockets (SocketKAP™) and provide structural support for sockets with defective bony walls (SocketKAGE™) in a non-human primate model. MATERIAL AND METHODS: Six Macaca fascicularis were imaged by cone beam computed tomography to register their preoperative alveolar bone...
April 19, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/28390826/estimation-of-date-of-death-through-wound-healing-of-an-extraction-socket-a-case-report
#10
Joan Viciano, Ruggero D'Anastasio, Cristian D'Ovidio, Sara Costantini, Aldo Carnevale, Luigi Capasso
Surgical extraction of teeth due to dental pathologies is a relatively common procedure in modern man. The healing of the wound that results occurs in gradual and sequential stages, such that the analysis of this repair process can be very useful in forensic investigations on human remains. The following study reports on a particular case where the remodeling of a tooth socket allowed an estimation of the time that had elapsed from the day of the surgical extraction of the tooth to the time of death. The corpse was that of a woman of 34 years...
March 27, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28384521/rna-isolation-from-alveolar-bone-and-gene-expression-analysis-of-rank-rankl-and-opg-a-new-tool-to-monitor-bone-remodeling-and-healing-in-different-bone-substitutes-used-for-prosthetic-rehabilitation
#11
Elena Canciani, Claudia Dellavia, Monica Gioia Marazzi, Davide Augusti, Daniela Carmagnola, Elena Vianello, Luigi Canullo, Emanuela Galliera
OBJECTIVE: (i) To validate a simple and efficient method for extracting high quality RNA from small samples of bone tissue, (ii) to test its application on limited amounts of grafted oral bone and (iii) to analyze the gene expression of the OPG/RANK/RANKL system and IL-6 in "spontaneous healing" and grafted tissue. DESIGN: 26 patients in need of extraction of one lower molar tooth were divided in 3 groups. In group A (8 patients) the alveolar socket was left for spontaneous healing, in group B (8 patients) it was filled with a hydroxyapatite scaffold while in group C (10 patients) it was filled with hydroxyapatite granules...
March 28, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28356687/evaluation-of-two-socket-healing-procedures-with-and-without-mesenchymal-stem-cells-a-comparative-study
#12
Abhinav Jain, Mahinder Singh, K P Ganapathy, Vikas Ramola, Deepak Passi, Komal Jain
AIMS AND OBJECTIVES: Successful preservation of the edentulous ridge after extraction may eliminate or reduce the need for ridge augmentation procedures. It is proved that grafting of fresh extraction sockets with bone grafts promotes ridge preservation. An objective method of maintaining height and width of alveolar ridge using mesenchymal stem cells (MSCs) seeded on collagen membrane was implemented in this study. METHODOLOGY: Ten bilaterally symmetrical extraction sockets scheduled for extraction were selected for this study...
July 2016: National Journal of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28356684/effects-of-honey-in-the-management-of-alveolar-osteitis-a-study
#13
Nikita Soni, Vibha Singh, Shadab Mohammad, R K Singh, U S Pal, Ranjana Singh, Jyatasana Aggrwal, Mahesh Pal
INTRODUCTION: Alveolar osteitis (AO) is a complication of tooth extraction which indicates inflammation of alveolar bone of either maxilla or mandible. This study uses Apitherapy where honey catalyses biological reactions to improve immune system, makes local environment unbearable for microorganisms in the affected socket and enhances healing. MATERIALS AND METHODS: 50 patients of AO were included in the study. After cleansing of the affected socket, honey dressing was applied...
July 2016: National Journal of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28348611/can-tert-butylhydroquinone-improve-the-healing-of-extracted-tooth-socket-in-rats
#14
Somayeh Khoramian Tusi, Tahereh Eslam Manesh, Mahmood Sheikh Fathollahi, Ali Bagherian
BACKGROUND: Tooth extraction causes an open wound in the soft and hard tissues. During the inflammatory phase of the healing process, a large amount of free radicals are produced and cause oxidative stress, which leads to tissue damage and delayed wound healing. Thus, in this study, we evaluated the effect of tert-butylhydroquinone (TBHQ), as an antioxidant, on the healing process of tooth sockets in rats. MATERIALS AND METHODS: To conduct this experimental study, male Wistar rats (n = 42) were divided into two groups...
January 2017: Dental Research Journal
https://www.readbyqxmd.com/read/28333394/socket-shield-technique-for-immediate-implant-placement-clinical-radiographic-and-volumetric-data-after-5%C3%A2-years
#15
Daniel Bäumer, Otto Zuhr, Stephan Rebele, Markus Hürzeler
OBJECTIVES: Implant placement immediately after tooth extraction is often accompanied by resorption of surrounding tissues. A clinical technique was developed where the buccal portion of the root is retained to preserve the periodontal ligament and bundle bone. This technique is based on animal studies showing the potential to preserve the facial tissues utilizing this approach. The purpose of this study was to gain more insight regarding the safety of the technique with regard to biological and implant-related long-term complications and to observe the clinical appearance of the peri-implant tissues...
March 23, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/28332068/photobiomodulation-with-led-and-laser-in-repair-of-mandibular-socket-rabbit-clinical-evaluation-histological-and-histomorphometric
#16
Cláudio Rômulo Comunian, Antônio Luis Neto Custódio, Leandro Junqueira de Oliveira, Carlos Eduardo Assis Dutra, Milton D'almeida Ferreira Neto, Cleuza Maria Faria Rezende
PURPOSE: The aim of this study was to evaluate the effects of LED and low-intensity laser on the healing of rabbit dental alveoli. METHODS: A total of 18 rabbits were divided into three groups of six; all rabbits underwent surgical extraction of the first lower right premolar. Following surgery, group 1 received LED irradiation, group 2 received laser irradiation, and group 3 were untreated controls. The initial applications of LED and laser began 48 h after tooth extraction and were given perpendicularly to the dental alveoli...
June 2017: Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28327692/immediate-immediate-delayed-6%C3%A2-weeks-and-delayed-4%C3%A2-months-post-extractive-single-implants-1-year-post-loading-data-from-a-randomised-controlled-trial
#17
Marco Esposito, Giovanni Zucchelli, Gioacchino Cannizzaro, Luigi Checchi, Carlo Barausse, Anna Trullenque-Eriksson, Pietro Felice
PURPOSE: To compare the clinical outcome of single implants placed immediately after tooth extraction with implants placed 6 weeks after tooth extraction (immediate-delayed placement), and with implants placed after 4-month extraction and socket healing (delayed placement). MATERIALS AND METHODS: Two-hundred and ten (210) patients requiring a single implant-supported crown to replace a tooth to be extracted were randomised to receive immediate post-extractive implants (70 patients), immediate-delayed implants at 6 weeks (70 patients), and delayed implants after 4 months of healing (70 patients) according to a parallel group design...
2017: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/28318924/aged-rats-under-zoledronic-acid-therapy-and-oral-surgery
#18
Mariza Akemi Matsumoto, Elisa Mara de Abreu Furquim, Alaíde Gonçalves, Joel Ferreira Santiago-Júnior, Patrícia Pinto Saraiva, Camila Lopes Cardoso, Marcelo Salles Munerato, Roberta Okamoto
INTRODUCTION: Aging brings a number of health conditions that can compromise the healing process in elderly individuals, significantly when it comes to bone tissue. The aim of the present study was to analyze the effects of zoledronic acid (ZL) therapy on socket healing of aged male rats. MATERIALS AND METHODS: Twenty-four Wistar male rats, 20 months old, underwent surgical procedures for the extraction of the upper right incisor and were divided into two groups according to the treatment: Control (C) - intravenous (IV) 0...
February 17, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28301383/radiographic-and-histological-evaluation-of-the-healing-of-extraction-sockets-filled-with-bovine-derived-xenograft-an-experimental-study-in-rats
#19
Fengjuan Zhou, Xiaofei Zheng, Meng Xie, Anchun Mo, Hongkun Wu
AIM: To evaluate the microenvironment changes in the sockets substituted with bovine-derived xenografts during the early healing period. MATERIALS AND METHODS: After extraction of the right maxillary incisor of Sprague Dawley rats, 48 rats were randomly divided into 2 groups. The extraction sockets of the test group were filled with Bio-Oss, whereas the control group was allowed to heal without intervention. The bone quality of the extraction sockets was observed through micro-CT and immunohistochemistry...
March 15, 2017: Implant Dentistry
https://www.readbyqxmd.com/read/28298826/alveolar-ridge-preservation-using-autogenous-tooth-graft-versus-beta-tricalcium-phosphate-alloplast-a-randomized-controlled-prospective-clinical-pilot-study
#20
Chaitanya Pradeep Joshi, Nitin Hemchandra Dani, Smita Uday Khedkar
BACKGROUND: A randomized, prospective clinical, radiographical, and histological study was conducted to evaluate healing after alveolar ridge preservation technique using two different graft materials, namely, a novel autogenous graft material i. e., autogenous tooth graft (ATG) and beta-tricalcium phosphate (β-TCP) alloplast. MATERIALS AND METHODS: Fifteen patients undergoing extraction of at least three teeth were selected. Atraumatic extractions were performed...
July 2016: Journal of Indian Society of Periodontology
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