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https://www.readbyqxmd.com/read/29148597/three-dimensional-analysis-of-bone-remodeling-following-ridge-augmentation-of-compromised-extraction-sockets-in-periodontitis-patients-a-randomized-controlled-study
#1
Mario Aimetti, Valeria Manavella, Lisa Corano, Elena Ercoli, Cristina Bignardi, Federica Romano
OBJECTIVES: The aim of this study was to analyze linear and volumetric hard tissue changes in severely resorbed alveolar sockets after ridge augmentation procedure and to compare them with spontaneous healing using three-dimensional cone beam computed tomography (CBCT). MATERIAL AND METHODS: Thirty patients (mean age 53.2 ± 6.3 years) requiring tooth extraction for advanced periodontitis were randomly allocated to test and control groups. The test sites were grafted using a collagenated bovine-derived bone (DBBM-C) covered with a collagen membrane, while control sites had spontaneous healing...
November 17, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/29142657/extraction-socket-preservation-using-porcine-derived-collagen-membrane-alone-or-associated-with-porcine-derived-bone-clinical-results-of-randomized-controlled-study
#2
Renzo Guarnieri, Luigi Stefanelli, Francesca De Angelis, Francesca Mencio, Giorgio Pompa, Stefano Di Carlo
Objectives: The aim of present randomized controlled clinical trial was to clinically evaluate hard tissue changes after extraction socket preservation procedures compared to natural spontaneous healing. Material and Methods: Thirty patients were enrolled in the present study and underwent single-tooth extraction in the premolar/molar areas. Ten sites were grafted with porcine-derived bone covered by collagen membrane, 10 covered by porcine-derived collagen membrane alone, and 10 underwent natural spontaneous healing...
July 2017: Journal of Oral & Maxillofacial Research
https://www.readbyqxmd.com/read/29135351/human-studies-of-vertical-and-horizontal-alveolar-ridge-augmentation-comparing-different-types-of-bone-graft-materials-a-systematic-review
#3
Suraj Chavda, Liran Levin
Alveolar ridge augmentation can be completed with various types of bone augmentation materials (autogenous, allograft, xenograft & alloplast). Currently autogenous bone is labelled as the "gold standard" due to faster healing times and integration between native and foreign bone. No systematic review has currently determined whether there is a difference of implant success between various bone augmentation materials. The purpose of this paper was to systematically review comparative human studies of vertical and horizontal alveolar ridge augmentation comparing different types of bone graft materials (autogenous, allograft, xenograft & alloplast)...
November 14, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/29120890/validity-of-collagen-plugs-for-ridge-preservation-in-a-canine-model
#4
Dong-Min Kim, Hyun-Chang Lim, Ji-Youn Hong, Seung-Il Shin, Jong-Hyuk Chung, Yeek Herr, Seung-Yun Shin
PURPOSE: The purpose of the present study was to evaluate healing outcomes after collagen plug insertion in extraction-related defects. MATERIALS AND METHODS: The third and fourth mandibular premolars in canines were extracted, and the septal bone was removed. The following treatments were performed for the defects: porcine atelo-collagen plug, bovine atelo-collagen plug, and no intervention (control). The experimental animals were killed after 6, 12, or 24 weeks (n = 4, respectively)...
November 7, 2017: Implant Dentistry
https://www.readbyqxmd.com/read/29095789/impact-of-inorganic-xenograft-on-bone-healing-and-osseointegration-an-experimental-study-in-rabbits
#5
Etiene Andrade Munhoz, Augusto Bodanezi, Tania Mary Cestari Biol, Márcia Sirlene Zardin Graeff, Osny Ferreira Junior, Paulo Sergio Perry de Carvalho, Rumio Taga
PURPOSE: To evaluate if an inorganic graft applied before implant insertion interferes with osseointegration. MATERIALS AND METHODS: The bilateral mandibular incisors of 12 rabbits were extracted. One of the sockets was randomly filled with an inorganic xenogenic bone graft, whereas the remaining socket was allowed to heal naturally and served as a control. After 60 days, titanium implants were inserted into healing areas. The animals were killed 60 days after. Bone depositions were marked with fluorochrome oxytetracycline, alizarin, and calcein and evaluated using confocal laser scanning microscopy...
November 1, 2017: Implant Dentistry
https://www.readbyqxmd.com/read/29082655/immediately-restored-full-arch-fixed-prosthesis-on-implants-placed-in-both-healed-and-fresh-extraction-sockets-after-computer-planned-flapless-guided-surgery-a-3-year-follow-up-study
#6
Giampiero Ciabattoni, Alessandro Acocella, Roberto Sacco
BACKGROUND: The treatment of patients by the use of immediate implant placement in post-extractive site is a challenging procedure. PURPOSE: A 3-year clinical and radiological study of post-extractive implants placed using flapless guided surgery and immediately functioning. MATERIALS AND METHODS: Thirty-two patients (23 females and 9 males), aged between 44 and 73 years (a mean age of 59.5) were treated with immediate full arch restorations and flapless implant surgery in fresh extraction and healed sites...
October 29, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29064761/comparing-the-healing-potential-of-late-stage-periodontitis-and-peri-implantitis
#7
Ryan Wong, Sarah Hiyari, Aline Yaghsezian, Mina Davar, Yi-Ling Lin, Maria Galvan, Sotirios Tetradis, Paulo M Camargo, Flavia Q Pirih
Peri-implantitis is defined as an inflammatory disease affecting the tissues around osseointegrated functioning implants. Unfortunately, detailed PI pathogenesis is not well understood and current treatments lack predictability. OBJECTIVE: Compare the healing potential of late-stage ligature-induced periodontitis (PD) and peri-implantitis (PI) after ligature removal. METHODS: Four-week-old C57BL/6J male mice had their left maxillary molars extracted. After eight weeks, implants were placed in healed sockets and allowed to osseointegrate...
October 24, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/29057266/tapered-double-lead-threads-single-implants-placed-in-fresh-extraction-sockets-and-healed-sites-of-the-posterior-jaws-a-multicenter-randomized-controlled-trial-with-1-to-3-years-of-follow-up
#8
Alessandro Cucchi, Elisabetta Vignudelli, Simonetta Franco, Luca Levrini, Dario Castellani, Luca Pagliani, Massimiliano Rea, Claudio Modena, Giulio Sandri, Carlo Longhi
PURPOSE: To evaluate the survival, success, and complication rates of tapered double-lead threads single implants, placed in fresh extraction sockets and healed sites of the posterior jaws. METHODS: The enrolled patients were randomly divided into 2 groups: in the test group (TG), all implants were inserted at the time of tooth extraction; in the control group (CG), all implants were placed 3 months after extraction. The implants were followed for a period of 1 to 3 years after loading...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29044525/susceptibility-of-different-mouse-strains-to-peri-implantitis
#9
S Hiyari, A Naghibi, R Wong, R Sadreshkevary, L Yi-Ling, S Tetradis, P M Camargo, F Q Pirih
BACKGROUND AND OBJECTIVE: Peri-implantitis (PI) is an inflammatory condition that affects the tissues surrounding dental implants. Although the pathogenesis of PI is not fully understood, evidence suggests that the etiology is multifactorial and may include a genetic component. The aim of this study was to investigate the role of genetics in the development of peri-implantitis. MATERIAL AND METHODS: Four-week-old C57BL/6J, C3H/HeJ and A/J male mice had their left maxillary molars extracted...
October 17, 2017: Journal of Periodontal Research
https://www.readbyqxmd.com/read/29043461/effect-of-anti-angiogenesis-induced-by-chemotherapeutic-monotherapy-chemotherapeutic-bisphosphonate-combination-therapy-and-anti-vegfa-mab-therapy-on-tooth-extraction-socket-healing-in-mice
#10
Yuri Akita, Shinichiro Kuroshima, Kazunori Nakajima, Hiroki Hayano, Riho Kanai, Muneteru Sasaki, Takashi Sawase
Osteonecrosis of the jaw (ONJ), which is a rare but severe adverse effect, mainly occurs in oncology patients receiving chemotherapeutic agents and bisphosphonates. However, the combined impact of chemotherapy and bisphosphonates on wound healing after tooth extraction remains unknown. The aim of this study was to determine the precise etiology of ONJ induced by chemotherapy and bisphosphonate combination therapy. Mice received zoledronate (ZA) monotherapy, cyclophosphamide (CY) monotherapy or CY/ZA combination therapy...
October 17, 2017: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/29034567/timeframe-of-socket-cortication-after-tooth-extraction-a-retrospective-radiographic-study
#11
Kristina Bertl, Edmund Benjamin Kukla, Rajaa Albugami, Florian Beck, André Gahleitner, Andreas Stavropoulos
OBJECTIVES: To assess the timeframe between tooth extraction and radiographically detectable socket cortication in humans. METHODS: Two hundred and fifty patients with a CT scan ≤36 months after tooth extraction were included. First, three orthoradial multiplanar reconstruction slices, representing the major part of the extraction socket, were scored regarding the degree of bone healing as (i) healed, that is, complete/continuous cortication of the socket entrance, or (ii) non-healed...
October 15, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/29033524/influence-of-platelet-rich-fibrin-on-post-extraction-socket-healing-a-clinical-and-radiographic-study
#12
Ahmed Abdullah Alzahrani, Afraa Murriky, Sami Shafik
AIM: The aim of this study was to evaluate clinically and radiographically, extraction socket healing using autologous platelet rich fibrin (PRF). MATERIALS AND METHODS: Twenty-four subjects needing single tooth simple extractions were selected. Twenty-four extraction sockets were divided into test group (PRF, n = 12) and control group (blood clot, n = 12). PRF was prepared with blood drawn from individuals after extraction using standard technique. PRF was placed in test group sockets followed by pressure application and figure 8 sutures...
October 2017: Saudi Dental Journal
https://www.readbyqxmd.com/read/29032403/mate-tea-ilex-paraguariensis-improves-bone-formation-in-the-alveolar-socket-healing-after-tooth-extraction-in-rats
#13
Matheus da Silva Brasilino, Camila Tami Stringhetta-Garcia, Camila Scacco Pereira, Ariana Aparecida Ferreira Pereira, Karina Stringhetta, Andréia Machado Leopoldino, Marcelo Macedo Crivelini, Edilson Ervolino, Rita Cássia Menegati Dornelles, Ana Cláudia de Melo Stevanato Nakamune, Antonio Hernandes Chaves-Neto
OBJECTIVES: The objective of this study was to investigate the effects of mate tea (MT) [Ilex paraguariensis] on alveolar socket healing after tooth extraction. MATERIALS AND METHODS: Sixteen male rats were divided into MT and control groups. MT was administered by intragastric gavage at a dose of 20 mg/kg/day for 28 days before and 28 days after right maxillary incisor extraction. The control group received an equal volume of water. Histopathological and histometric analysis of the neoformed bone area and osteocyte density were performed, as well as immunohistochemical analysis of osteocalcin (OCN), receptor activator of nuclear factor kappa-B ligand (RANKL), osteoprotegerin (OPG), tartrate-resistant acid phosphatase (TRAP), and manganese superoxide dismutase (MnSOD) in the alveolar socket...
October 14, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28987501/composite-alginate-hyaluronan-sponges-for-the-delivery-of-tranexamic-acid-in-post-extractive-alveolar-wounds
#14
Ovidio Catanzano, Vittoria D'Esposito, Pietro Formisano, Joshua S Boateng, Fabiana Quaglia
The management of wounds in patients on anticoagulant therapy who require oral surgical procedures is problematic and often results in a non-satisfactory healing process. Here we report a method to prepare an advanced dressing able to avoid uncontrolled bleeding by occluding the post-extractive alveolar wounds, and simultaneously, capable of a fast release of tranexamic acid (TA). Composite alginate/hyaluronan (ALG/HA) sponge dressings loaded with TA were prepared by a straightforward internal gelation method followed by a freeze-drying step...
October 5, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28982352/how-effective-is-collagen-resorbable-membrane-placement-after-partially-impacted-mandibular-third-molar-surgery-on-postoperative-morbidity-a-prospective-randomized-comparative-study
#15
Adnan Kilinc, Mert Ataol
BACKGROUND: Collagen membranes have some benefits include promoting wound healing through isolation, clot stabilization, wound stability, and hemostasis, enhancing primary wound coverage through its chemotactic ability to attract fibroblasts, and augmenting flap thickness by providing a collagenous scaffold. The purpose of this study was to compare primary and secondary healing and collagen membrane-based primary healing after surgical removal of partial impacted mandibular third molars, evaluating the incidence of postoperative complications and analyzing the swelling, mouth opening, and pain...
October 5, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28977730/histomorphometric-analysis-of-the-healing-process-after-the-replantation-of-rat-teeth-maintained-in-bovine-milk-whey-and-whole-milk
#16
Ana Paula Simões Corrêa, Pedro Henrique Silva Gomes Ferreira, Sônia Regina Panzarini, Celso Koogi Sonoda, Eliana Aparecida Caliente, Wilson Roberto Poi
BACKGROUND/AIM: In cases of tooth avulsion, a minimal extra-alveolar dry storage period or the use of a suitable storage medium is crucial to maintaining the vitality of the periodontal ligament. Whey has similar properties to milk and has therefore been investigated as a storage medium for avulsed teeth. The aim of the present study was to evaluate the repair process after replantation of rat teeth kept in whey and whole milk. MATERIAL AND METHODS: Thirty-six male rats were divided into four groups of nine animals...
October 4, 2017: Dental Traumatology: Official Publication of International Association for Dental Traumatology
https://www.readbyqxmd.com/read/28974709/a-novel-method-in-the-removal-of-impacted-mandibular-third-molar-buccal-drainage
#17
Ting Hu, Ji Zhang, Jing Zhi Ma, Le Nan Shao, Yi Fei Gu, Dian Qi Li, Liang Jiang, Yun Qiang Yang
Food impaction after impacted mandibular third molar extraction is a serious problem that should not be ignored. Incomplete suturing of the distal incision in the conventional method is the main cause of food impaction and delayed wound healing. The present study introduces a novel suture and drainage technology that requires hermetic suturing of the distal incision and rubber drainage for buccal drainage. 76 patients with horizontally/mesially impacted third molars (bilateral) were enrolled in this prospective study...
October 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28971532/new-bone-formation-and-trabecular-bone-microarchitecture-of-highly-porous-tantalum-compared-to-titanium-implant-threads-a-pilot-canine-study
#18
Jin Whan Lee, Hai Bo Wen, Prabhu Gubbi, Georgios E Romanos
AIM: This study evaluated new bone formation activities and trabecular bone microarchitecture within the highly porous region of Trabecular Metal™ Dental Implants (TM) and between the threads of Tapered Screw-Vent® Dental Implants (TSV) in fresh canine extraction sockets. MATERIALS AND METHODS: Eight partially edentulated dogs received four implants (4.1 mmD × 13 mmL) bilaterally in mandibular fresh extraction sockets (32 TM, 32 TSV implants), and allowed to heal for 2, 4, 8, and 12 weeks...
October 2, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/28958784/long-term-therapy-with-intravenous-zoledronate-increases-the-number-of-nonattached-osteoclasts
#19
Maria José H Nagata, Michel R Messora, Cristina Antoniali, Stephen E Fucini, Natália de Campos, Natália M Pola, Carolina S Santinoni, Flávia A C Furlaneto, Edilson Ervolino
The purpose of this study was to investigate the influence of long-term therapy with intravenous zoledronate (ZA) on the healing of extraction sockets in rats. Forty rats, divided into groups C (Control) and Z (Zoledronate), received intravenous injections of either saline solution or ZA for 24 weeks. Their right maxillary incisor was extracted. Euthanasia was performed at 7 or 28 days postoperative. Histomorphometric (Newly Formed Bone Area) and immunohistochemical (RANKL, OPG and TRAP) analyses were performed...
August 19, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28954199/zoledronate-impairs-socket-healing-after-extraction-of-teeth-with-experimental-periodontitis
#20
A Soundia, D Hadaya, N Esfandi, I Gkouveris, R Christensen, S M Dry, O Bezouglaia, F Pirih, N Nikitakis, T Aghaloo, S Tetradis
Osteonecrosis of the jaws (ONJ) is a rare but severe complication of antiresorptive medications, such as bisphosphonates, used in the treatment of bone malignancy or osteoporosis. Tooth extraction and dental disease have been strongly associated with ONJ development. Here, we investigated molecular and cellular markers of socket healing after extraction of healthy or teeth with experimental periodontitis (EP) in Wistar-Han rats treated with zoledronic acid (ZA). We included 4 experimental groups: vehicle-treated animals with extraction of healthy teeth or teeth with ligature-induced EP and ZA-treated animals with extraction of healthy teeth or teeth with EP...
September 1, 2017: Journal of Dental Research
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