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Socket healing

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https://www.readbyqxmd.com/read/27909893/osteogain%C3%A2-loaded-onto-an-absorbable-collagen-sponge-induces-attachment-and-osteoblast-differentiation-of-st2-cells-in-vitro
#1
Richard J Miron, Masako Fujioka-Kobayashi, Yufeng Zhang, Anton Sculean, Benjamin Pippenger, Yoshinori Shirakata, Umadevi Kandalam, Maria Hernandez
OBJECTIVES: Dimensional changes of the alveolar bone following tooth extraction are a major challenge in daily dental practice. To limit bone loss, a variety of biomaterials including bone grafts, barrier membranes, and growth factors have been utilized either alone or in combination therapies to increase the speed and quality of new bone formation. The aim of the present in vitro study was to investigate the regenerative potential of Osteogain®, a new liquid carrier system of enamel matrix derivative (EMD) in combination with an absorbable collagen sponge (ACS) specifically designed for extraction socket healing...
December 1, 2016: Clinical Oral Investigations
https://www.readbyqxmd.com/read/27883211/tissue-changes-after-ridge-preservation-with-two-xenografts-preliminary-results-from-a-multicenter-randomized-controlled-clinical-trial
#2
Antonio Barone, Paolo Toti, Alessandro Quaranta, Fortunato Alfonsi, Alessandro Cucchi, Bruno Negri, Roberto Di Felice, Saverio Marchionni, Jose' Luis Calvo-Guirado, Ugo Covani, Ulf Nannmark
OBJECTIVES: To evaluate and compare clinical and histological changes after ridge preservation procedures with those of spontaneous healing. MATERIALS_AND_METHODS: Ninety patients were enrolled in the present randomized controlled clinical trial and underwent single-tooth extraction in the premolar/molar areas. Thirty sites were grafted with collagenated cortico-cancellous (coll), 30 sites with cortical (cort) porcine bone and 30 sites underwent natural healing. Primary (vertical and horizontal bone changes after 3-month) and secondary outcomes (histomorphometric after 3 months) were evaluated at implant placement...
November 24, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27861665/reactive-soft-tissue-preservation-in-maxillary-large-bone-defects
#3
Roberto Crespi, Paolo Capparé, Patrizio Bollero, Renato Pagani, Giorgio Gastaldi, Enrico F Gherlone
PURPOSE: Granulation tissue containing reactive soft tissue with potential multipotent stem cells can help socket healing following extraction. The aim of this study was to assess bone healing of maxillary large bone defects while maintaining reactive soft tissue. MATERIALS AND METHODS: A total of 32 patients presenting large bone defects were selected for this prospective study. Eight patients (Group A) presented with large bone defects but an intact buccal cortical plate, while 24 patients (Group B) presented with large bone defects lacking a buccal cortical plate...
November 2016: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/27857817/conservative-socket-regeneration-with-buccal-wall-defect-using-guided-tissue
#4
Mohammed Jasim Al-Juboori
Progressive alveolar bone resorption after tooth extraction may lead to surgical and prosthetic-driven difficulties, especially when deciding to use a dental implant to replace the extracted tooth. This case report discusses an irreparable lower left second premolar tooth with a periodontal lesion on the buccal side. A preservative tooth extraction was performed. Then, the socket was grafted with bovine bone, a collagen membrane was placed between the buccal bone and the attached gingiva, covering the bone dehiscence buccally, and the socket without a flap was raised...
2016: Open Dentistry Journal
https://www.readbyqxmd.com/read/27857769/socket-preservation-using-freeze-dried-bone-allograft-with-and-without-plasma-rich-in-growth-factors-in-dogs
#5
Mohammad Hasan Samandari, Abbas Haghighat, Nakisa Torabinia, Mehdi Taghian, Leyli Sadri, Vahid Naemy
BACKGROUND: Plasma rich in growth factors (PRGF) and freeze-dried bone allograft (FDBA) are shown to promote bone healing. This study was aimed to histologically and histomorphometrically investigate the effect of combined use of PRGF and FDBA on bone formation, and compare it to FDBA alone and control group. MATERIALS AND METHODS: The distal roots of the lower premolars were extracted bilaterally in four female dogs. Sockets were randomly divided into FDBA + PRGF, FDBA, and control groups...
September 2016: Dental Research Journal
https://www.readbyqxmd.com/read/27837344/platelet-rich-fibrin-may-reduce-the-risk-of-delayed-recovery-in-tooth-extracted-patients-undergoing-oral-bisphosphonate-therapy-a-trial-study
#6
Takuya Asaka, Noritaka Ohga, Yutaka Yamazaki, Jun Sato, Chiharu Satoh, Yoshimasa Kitagawa
OBJECTIVES: The aim of the present study was to evaluate the effectiveness of platelet-rich fibrin (PRF) as a wound-healing accelerator in patients undergoing oral bisphosphonate therapy and requiring tooth extractions. MATERIALS AND METHODS: A total of 102 patients were divided into a PRF group and control group. The patients received oral bisphosphonate therapy for osteoporosis for an average of 32 months. Blood was collected and PRF was introduced into the socket of the PRF group only...
November 11, 2016: Clinical Oral Investigations
https://www.readbyqxmd.com/read/27807485/treatment-of-an-erratic-extraction-socket-for-implant-therapy-in-a-patient-with-chronic-periodontitis
#7
Yusuke Hamada, Srividya Prabhu, Vanchit John
As implant therapy becomes more commonplace in daily practice, preservation and preparation of edentulous sites are key. Many times, however, implant therapy may not be considered at the time of tooth extraction and additional measures are not taken to conserve the edentulous site. While the healing process in extraction sockets has been well investigated and bone fill can be expected, there are cases where even when clinicians perform thorough debridement of the sockets, connective tissue infiltration into the socket can occur...
2016: Case Reports in Dentistry
https://www.readbyqxmd.com/read/27788625/evaluation-of-healing-at-molar-extraction-sites-with-and-without-ridge-preservation-a-randomized-controlled-clinical-trial
#8
Christopher J Walker, Thomas J Prihoda, Brian L Mealey, David J Lasho, Marcel Noujeim, Guy Huynh-Ba
BACKGROUND: To date, limited evidence is available specifically evaluating ridge preservation (RP) and implant placement in molar sites. The primary aim of this study was to radiographically compare alveolar ridge changes with and without RP with cone-beam computed tomography (CBCT). METHODS: This parallel, two-arm RCT included forty patients evenly distributed between two treatment groups. Following molar extraction, sites were allowed to heal naturally or received RP with freeze-dried bone allograft covered by a non-resorbable dense polytetrafluoroethylene (dPTFE) membrane...
October 27, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27777115/scanning-electron-microscopy-study-of-new-bone-formation-following-small-and-large-defects-preserved-with-xenografts-supplemented-with-pamidronate-a-pilot-study-in-fox-hound-dogs-at-4-and-8-weeks
#9
Naroa Lozano-Carrascal, Marta Satorres-Nieto, Rafael Delgado-Ruiz, José Eduardo Maté-Sánchez de Val, Sergio Alexandre Gehrke, Jorge Gargallo-Albiol, José Luis Calvo-Guirado
The aim of the present study was to evaluate the feasibility of SEM and EDX microanalysis on evaluating the effect of porcine xenografts (MP3(®)) supplemented with pamidronate during socket healing. Mandibular second premolars (P2) and first molars (M1) were extracted from six Beagle dogs. P2 were categorized as small defects (SD) and M1 as large defects (LD). Four random groups were created: SC (small control defects with MP3(®)), ST (small test defects MP3(®)+pamidronate), LC (large control defects with MP3(®)), and LT (large test defects MP3(®)+pamidronate)...
October 21, 2016: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/27771163/influence-of-secondary-wound-healing-after-mandibular-third-molar-coronectomy
#10
S Franco, E Vignudelli, G Monaco, C Marchetti
Our aim was to describe the postoperative morbidity related to secondary wound healing after coronectomy. Ten of 116 patients treated by coronectomy healed by second intention as a result of failed sutures. We made a retrospective analysis after two years to evaluate the postoperative morbidity related to secondary wound healing. The complete closure of the alveolus of the 10 surgical sites was recorded three months after coronectomy. No patients had postoperative infections, dry socket, or pulpitis. All patients were free of symptoms, the retained roots were completely included, and were not detectable with a periodontal probe...
October 19, 2016: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/27752199/effect-of-diode-laser-on-healing-of-tooth-extraction-socket-an-experimental-study-in-rabbits
#11
Shehab Ahmed Hamad, Jandar S Naif, Mahdi A Abdullah
OBJECTIVES: To evaluate the effect of low-level laser therapy on healing of extracted tooth socket of healthy rabbits. DESIGN: The sample of this study was 20 male rabbits of 2-2.5 kg weight with age range of 8-12 months. Right and left lower first premolar teeth were extracted. The extraction sockets of lower right first premolar were irradiated with 0.9 W gallium-aluminum-arsenide (GaAlAs) diode laser for 5 min, immediately after extraction and then every 72 h for the next 12 days...
September 2016: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/27746007/are-systemic-antibiotics-necessary-in-the-prevention-of-wound-healing-complications-after-intra-alveolar-dental-extraction
#12
O M Gbotolorun, I M Dipo-Fagbemi, A O Olojede, S Ebigwei, J O Adetoye
This double-blind, randomized controlled study was done to assess the necessity of systemic antibiotics in the prevention of wound healing complications after intra-alveolar dental extraction. A consecutive recruitment method was used to allocate participants to two treatment groups. Subjects in group A (antibiotics group, n=75) received amoxicillin and metronidazole for 5 days postoperatively, while those in group B (placebo group, n=75) were given identical-looking placebo drugs in place of the antibiotics...
October 13, 2016: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27741331/dimensional-changes-following-immediate-and-delayed-implant-placement-a-histomorphometric-study-in-the-canine
#13
Hee-Yong Yi, Young-Seok Park, Benjamin E Pippenger, Bongho Lee, Richard J Miron, Michel Dard
PURPOSE: The placement of immediate implants has become a routine treatment modality for the replacement of missing teeth. The aim of the present study was to evaluate dimensional changes of hard tissues following tooth extraction, implant bed preparation, and the subsequent integration of titanium implants placed immediately or following an 8-week healing period. MATERIALS AND METHODS: All mandibular premolars were extracted and used as experimental sites in five beagle dogs...
October 14, 2016: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/27740654/extraction-socket-management-with-buccal-plate-expansion-preliminary-results-of-a-novel-technique
#14
Alberto Fernandez Ayora, Oscar González-Martín, Eric Rompen, Geoffrey Lecloux, France Lambert
The primary objective of this pilot study was to evaluate a new socket preservation technique involving the intentional expansion of the extraction socket buccal plate using a flapless internal corticotomy and biomaterials. A total of 11 patients requiring tooth extraction were enrolled in this study. The aim of this technique was to maintain or improve the hard and soft tissue contour of the ridge after tooth extraction. All surgical sites healed uneventfully. Significant alveolar bone dimension changes were observed in the coronal region of the ridge (-1...
November 2016: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/27740650/socket-preservation-with-d-ptfe-membrane-histologic-analysis-of-the-newly-formed-matrix-at-membrane-removal
#15
Domenico Laurito, Riccardo Cugnetto, Marco Lollobrigida, Fabrizio Guerra, Annarita Vestri, Francesca Gianno, Sandro Bosco, Luca Lamazza, Alberto De Biase
This study aimed to evaluate the efficacy of an exposed high-density polytetrafluoroethylene (d-PTFE) membrane in preventing epithelial migration in postextraction sockets. For this purpose, a histologic description of the newly formed soft tissue underlying the membrane is presented. The periodontal status of the adjacent teeth was also evaluated to assess the gingival response. Ten premolar extraction sockets were treated. After tooth extraction, the sockets were filled with nanocrystalline hydroxyapatite and covered with d-PTFE membranes...
November 2016: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/27727104/differential-modulation-of-zoledronate-and-etidronate-in-osseous-healing-of-an-extracted-socket-and-tibia-defect
#16
Shin Saeng Lim, Beomseok Lee, In Sook Kim, Soon Jung Hwang
OBJECTIVES: Osteonecrosis of the jaw has been increasing after dentoalveolar surgery in patients treated with an antiresorptive bisphosphonate (BP), especially strong zoledronate (ZA). The pathophysiology underlying why osteonecrosis occurs exclusively in the jaw bone remains unclear. This study investigated skeletal site-specific bone healing during the use of BPs to explore the preferential incidence of osteonecrosis of the jaw bone. STUDY DESIGN: Extraction of mandibular molar and creation of a tibia defect were performed in rats 2 weeks after weekly intravenous injections with the potent ZA and the weaker BP etidronate...
August 18, 2016: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/27723188/the-conometric-concept-definitive-fixed-lithium-disilicate-restorations-supported-by-conical-abutments
#17
Marco Degidi, Diego Nardi, Gianluca Sighinolfi, Adriano Piattelli
PURPOSE: The use of the conical coupling connection to support definitive restorations was evaluated in cases involving full acrylic resin or hybrid acrylic resin-composite prostheses. The aim of this study was to evaluate the performance of definitive fixed partial prostheses made with lithium disilicate and supported by coupling connection abutments and healed implants. MATERIALS AND METHODS: The prostheses were placed in the posterior regions of partially edentulous patients; 65 patients received fixed lithium disilicate restorations splinted with conical coupling connections to two implants...
October 10, 2016: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/27722224/single-post-extractive-ultra-wide-7%C3%A2-mm-diameter-implants-versus-implants-placed-in-molar-healed-sites-after-socket-preservation-for-molar-replacement-6-month-post-loading-results-from-a%C3%A2-randomised-controlled-trial
#18
Marco Tallarico, Erta Xhanari, Milena Pisano, Giacomo De Riu, Antonio Tullio, Silvio Mario Meloni
PURPOSE: To test the hypothesis that there is no difference in clinical, radiographic and aesthetic outcomes positioning single post-extractive ultra-wide 7 mm-diameter implants or waiting 4 months to place implant, after molar extraction and the socket preservation procedure. MATERIAL AND METHODS: Patients requiring one implant-supported single restoration to replace a failed tooth in the molar region of both maxilla and mandible were selected. Patients were randomised according to a parallel group design into two arms: implant installation in fresh extraction sockets augmented with corticocancellous heterologous bone and porcine derma (group A) or delayed implant installation 4 months after tooth extraction and socket preservation using the same materials (group B)...
2016: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/27722222/immediate-immediate-delayed-6%C3%A2-weeks-and-delayed-4%C3%A2-months-post-extractive-single-implants-4-month-post-loading-data-from-a-randomised-controlled-trial
#19
Pietro Felice, Giovanni Zucchelli, Gioacchino Cannizzaro, Carlo Barausse, Michele Diazzi, Anna Trullenque-Eriksson, Marco Esposito
PURPOSE: To compare the clinical outcome of single implants placed immediately after tooth extraction with implants placed 6 weeks after tooth extraction (immediate-delayed placement), and with implants placed after 4 months of extraction and socket healing (delayed placement). MATERIALS AND METHODS: Two hundred and ten patients requiring a single implant-supported crown to replace a tooth to be extracted were randomised to receive immediate post-extractive implants (70 patients), immediate-delayed implants at 6 weeks (70 patients), and delayed implants after 4 months of healing (70 patients), according to a parallel group design...
2016: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/27712001/alveolar-ridge-preservation-after-tooth-extraction-a-bayesian-network-meta-analysis-of-grafting-materials-efficacy-on-prevention-of-bone-height-and-width-reduction
#20
Oreste Iocca, Alessio Farcomeni, Simon Pardiñas-Lopez, Huzefa S Talib
AIMS: To conduct a traditional meta-analysis and a Bayesian Network meta-analysis to synthesize the information coming from Randomized Controlled Trials on different socket grafting materials and combine the resulting indirect evidence in order to make inferences on treatments that have not been compared directly. MATERIALS AND METHODS: RCTs were identified for inclusion in the systematic review and subsequent statistical analysis. Bone height and width remodeling were selected as the chosen summary measures for comparison...
October 6, 2016: Journal of Clinical Periodontology
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