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Socket healing

Parveen Akhter Lone, Syed Wakeel Ahmed, Vivek Prasad, Bashir Ahmed
Plants & their extracts have immense potential for the management or treatment of the wounds. The pyhto medicines for the wound healing are not only cheap & affordable but are purportedly safe as hypersensitivity reactions are rarely encountered with the use of these agents, these natural agents induce healing & regeneration of the lost tissue by multiple mechanisms Turmeric commonly is called as Haldi in Hindi. C Longa has been reported to possess anti bacterial, anti fungal & anti inflammatory activities...
January 2018: Journal of Oral Biology and Craniofacial Research
Youngil Kwon, Hyunjung Ko, Soojung Kim, Miri Kim
BACKGROUND/AIM: Continuous research efforts have been focusing on promoting healing of delayed replantation of avulsed teeth. The aim of this in vivo study was to assess the effect of cathepsin K inhibitor surface treatment on delayed tooth replantation.Materials and Methods Thirty-four premolar roots of four beagle dogs were extracted and conventional root canal treatment was performed. The canals were filled with gutta-percha and cement. All extracted teeth were air-dried for 1 h. Teeth were divided into two groups according to the root surface treatment prior to replantation: control (n = 13) and cathepsin K inhibitor (n = 21)...
March 13, 2018: Dental Traumatology: Official Publication of International Association for Dental Traumatology
Cristiano Tomasi, Mauro Donati, Denis Cecchinato, Isacco Szathvary, Enrico Corrà, Jan Lindhe
OBJECTIVE: To examine if (i) characteristics of the fresh extraction socket site influenced subsequent dimensional alterations and (ii) placement of deproteinized bovine mineral in the socket affected volumetric change during healing. MATERIALS AND METHODS: Twenty seven subjects and 28 extraction sites were included. Immediately after the removal of the tooth and after 6 months of healing, stone and virtual models of the jaw were produced. A cone beam computerized tomography scan was obtained immediately after extraction and the thickness of the buccal bone wall at the extraction site was measured...
March 13, 2018: Clinical Oral Implants Research
Sang-Joun Yu, Yoon Seon Lee, Han-Wool Choung, Yeoung-Hyun Park, Byung-Ock Kim, Joo-Cheol Park
Preameloblast-conditioned medium (PACM) has been reported as a potent dentin regenerative material, but its effects as a mixture on periodontal regeneration and the role of CPNE7 in PACM are not known. The purpose of this study is to evaluate the histologic and histomorphometric effects of preameloblast-conditioned medium (PACM) and CPNE7 on periodontal tissue healing in dogs. Seventy-two mandibular premolar roots from ten dogs were extracted and randomly divided into six groups (n = 12 each): (1) positive control group; (2) negative control group; (3) cementum-removed and PACM-treated group; (4) cementum-preserved and PACM-treated group; (5) CPNE7-inactivated PACM-treated group; and (6) recombinant CPNE7-treated group...
March 10, 2018: Journal of Molecular Histology
C E Mohn, G R Troncoso, C Bozzini, M I Conti, J J Fernandez Solari, J C Elverdin
Saliva is very important to oral health, and a salivary deficit has been shown to bring serious problems to oral health. There is scant information about the mechanisms through which salivary glands participate in post-tooth extraction socket healing. Therefore, the aim of the present study was to investigate the effect of submandibulectomy (SMx), consisting of the ablation of submandibular and sublingual glands (SMG and SLG, respectively), on PGE2 signaling and other bone regulatory molecules, such as OPG and RANKL, involved in tooth extraction socket healing...
March 10, 2018: Wound Repair and Regeneration
Stefano Sivolella, Chiara Perin, Marco Capecchi, Valerio Buongiorno, Marialuisa Valente
Lateral periodontal cysts (LPCs) are rare odontogenic cysts of developmental origin. A 52-year-old man presented with an asymptomatic gingival swelling located between the mandibular left canine and first premolar, both of which were vital. Radiography showed a well-circumscribed radiolucent area and loss of the lamina dura around the tooth socket in contact with the lesion and of the interproximal buccal bone. The lesion was enucleated. The defect was immediately grafted with a 1:1 mixed autologous and heterologous bone graft covered with a collagen membrane...
March 7, 2018: International Journal of Periodontics & Restorative Dentistry
Federico Tirone, Stefano Salzano, Marco Pagano
Healing of extraction sockets may sometimes result in formation of fibrous tissue instead of bone, even after 4 months, an occurrence that may hinder implant placement. The aim of this preliminary observational study was to histologically evaluate quality and amount of bone regeneration after treating nonhealing sockets with a bovine-derived xenograft enriched with porcine collagen (Bio-Oss Collagen, Geistlich) without barrier membranes. Biopsy specimens were collected during implant placement, 4 months after grafting...
March 7, 2018: International Journal of Periodontics & Restorative Dentistry
Yaniv Mayer, Ofir Ginesin, Alaa Khutaba, Eli E Machtei, Hadar Zigdon Giladi
BACKGROUND: Cells, scaffolds, and growth factors are the key components in bone tissue engineering. Scaffold composition, topography, and architecture influence the amount of regenerated bone in the implantation site. The aims of the study were to compare viability and proliferation of mesenchymal stem cells (MSCs) seeded onto two commercial xenografts: Bio-Oss (BO) and bioactive bone bovine (BB). Next, these materials were compared for histomorphometric bone formation in a socket preservation model in rats...
March 6, 2018: Clinical Implant Dentistry and related Research
Otto Zuhr, Stephan F Rebele, Stefani L Cheung, Markus B Hürzeler
Diverse clinical advancements, together with some relevant technical innovations, have led to an increase in popularity of tunneling flap procedures in plastic periodontal and implant surgery in the recent past. This trend is further promoted by the fact that these techniques have lately been introduced to a considerably expanded range of indications. While originally described for the treatment of gingival recession-type defects, tunneling flap procedures may now be applied successfully in a variety of clinical situations in which augmentation of the soft tissues is indicated in the esthetic zone...
March 1, 2018: Periodontology 2000
Peter Fairbairn, Minas Leventis, Chas Mangham, Robert Horowitz
This case report highlights the use of a novel in situ hardening synthetic (alloplastic), resorbable, bone grafting material composed of beta tricalcium phosphate and calcium sulfate, for alveolar ridge preservation. A 35-year-old female patient was referred by her general dentist for extraction of the mandibular right first molar and rehabilitation of the site with a dental implant. The nonrestorable tooth was "atraumatically" extracted without raising a flap, and the socket was immediately grafted with the synthetic biomaterial and covered with a hemostatic fleece...
2018: Case Reports in Dentistry
Ronald E Jung, Alexis Ioannidis, Christoph H F Hämmerle, Daniel S Thoma
In the esthetic zone, in the case of tooth extraction, the clinician is often confronted with a challenge regarding the optimal decision-making process for providing a solution using dental implants. This is because, after tooth extraction, alveolar bone loss and structural and compositional changes of the covering soft tissues, as well as morphological alterations, can be expected. Ideally, the therapeutic plan starts before tooth extraction and it offers three options: spontaneous healing of the extraction socket; immediate implant placement; and techniques for preserving the alveolar ridge at the site of tooth removal...
February 27, 2018: Periodontology 2000
J Y Liu, F Chen, Y J Ge, L Wei, S X Pan, H L Feng
OBJECTIVE: To evaluate the influence of the rough surface of dental implants prepared by selective laser melting (SLM) on early bone healing around titanium implants. METHODS: A total of sixteen titanium implants were involved in our research, of which eight implants were prepared by SLM (TIXOS Cylindrical, Leader-Novaxa, Milan, Italy; 3.3 mm×10 mm, internal hex) and the other eight were sandblasted, large-grit and acid-etched (SLA) implants (IMPLUS Cylindrical, Leader-Novaxa, Milan, Italy; 3...
February 18, 2018: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
Victor Tu, Satish Kumar
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Alveolar ridge preservation after tooth extraction: a Bayesian Network meta-analysis of grafting materials efficacy on prevention of bone height and width reduction. Iocca O, Farcomeni A, Pardiñas Lopez S, Talib HS. J Clin Periodontol 2017; 44(1):104-14. SOURCE OF FUNDING: Self-funded by the authors and their institutions TYPE OF STUDY/DESIGN: Meta-analysis and Bayesian network meta-analysis.
March 2018: Journal of Evidence-based Dental Practice
Jordan Antetomaso, Satish Kumar
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Immediate implant placement into fresh extraction sockets versus delayed implants into healed sockets: a systematic review and meta-analysis. Mello CC, Lemos CAA, Verri FR, Dos Santos DM, Goiato MC, Pellizzer EP. Int J Oral Maxillofac Surg 2017; 46(9):1162-77. SOURCE OF FUNDING: None TYPE OF STUDY/DESIGN: Systematic review with meta-analysis of data.
March 2018: Journal of Evidence-based Dental Practice
H Unsal, G N H Erbasar
Aims: To evaluate whether the alveolar osteitis (AO) incidence after extracting partially erupted third molars differs when platelet-rich fibrin (PRF) is administered in the alveolar socket and to assess the influence of PRF on postoperative pain levels and periodontal probing depth. Settings and Design: In this split-mouth randomized study, 50 patients (17 men/ 33 women; mean age, 23.96 years) with bilateral symmetric partially erupted mandibular third molars were enrolled...
February 2018: Nigerian Journal of Clinical Practice
Yingdi Zhang, Zheng Ruan, Minhua Shen, Luanjun Tan, Weiqin Huang, Lei Wang, Yuanliang Huang
The aim of the present study was to evaluate the clinical efficacy of platelet-rich fibrin (PRF) in preserving the alveolar ridge following human tooth extraction. A total of 28 patients were divided into two groups: The experimental and control groups (n=14 each). Following tooth extraction, the experimental group was implanted with PRF membrane, whereas the control group was not. The gingival healing effect was assessed at 7 days, 1 and 3 months later. Cone-beam computed tomography was performed immediately and at 3 months following tooth extraction...
March 2018: Experimental and Therapeutic Medicine
José Luis Calvo Guirado, Pilar Cegarra Del Pino, Lari Sapoznikov, Rafael Arcesio Delgado Ruíz, Manuel Fernández Dominguez, Sérgio Alexandre Gehrke
OBJECTIVES: To investigate freshly extracted dental particulate used to graft post-extraction sockets in dogs, comparing new bone formation at experimental and control sites. MATERIAL AND METHODS: Bilateral premolars P2, P3, P4 and first mandibular molars were extracted atraumatically from six American Fox Hound dogs. The teeth were ground immediately using a 'Smart Dentin Grinder.' The dentin particulate was sieved to ensure a grain size of 300-1200μm and immersed in an alcohol cleanser to dissolve organic debris and bacteria, followed by washing in sterile saline buffer solution...
February 15, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
Keunhee Kim, Hee-Seung Choi, Nan-Sim Pang
This report presents two cases of tooth autotransplantation using cone-beam computed tomography (CBCT), the three-dimensional (3D) simulation dental planning software and a computer-aided rapid prototyping (CARP) model. Two hopeless teeth of adult patients were replaced as their third molar teeth. Before deciding the autotransplantation, diagnostic CBCT images were acquired and imported to SimPlant software. The SimPlant dental program was used for surgical simulation prior to autotransplantation, which created 3D images of the available donor teeth and recipient site tooth and superimposed the images to display their morphological similarity...
February 16, 2018: Australian Endodontic Journal: the Journal of the Australian Society of Endodontology Inc
Fouad Khoury, Romain Doliveux
The aim of this study was to evaluate a new minimally invasive surgical technique for the reconstruction of critical-size bony defect with local harvested bone core with simultaneous implant placement. In a prospective study, 186 consecutively treated patients were included and controlled clinically and radiologically for at least 5 years postoperative. Every patient presented a bony defect affecting the buccal, lingual, or palatal wall. In all cases, the alveolar crest was wide enough to allow implant placement inside the bony contours...
March 2018: International Journal of Periodontics & Restorative Dentistry
Renzo Guarnieri, Luca Testarelli, Luigi Stefanelli, Francesca De Angelis, Francesca Mencio, Giorgio Pompa, Stefano Di Carlo
Objectives: The present paper reports data of a randomized study aimed to analyse and compare the histologic and histomorphometric aspects of bone healing in extraction sites covered with collagen membrane alone or associated with porcine-derived bone graft. Material and Methods: Thirty patients, with single extraction sockets without severe bone wall defects in the premolar/molar region, were included. Ten extraction sockets were grafted with porcine-derived bone and covered with collagen membrane (group 1), 10 sites were covered with collagen membrane alone (group 2), and 10 sites healed spontaneously (group 3)...
October 2017: Journal of Oral & Maxillofacial Research
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