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https://www.readbyqxmd.com/read/28921659/ligature-induced-peri-implantitis-and-periodontitis-in-mice
#1
Sarah Hiyari, Ryan Wong, Aline Yaghsezian, Azadi Naghibi, Sotirios Tetradis, Paulo M Camargo, Flavia Q Pirih
AIM: Peri-implantitis (PI), inflammation around dental implants, shares characteristics with periodontitis (PD). However, PI is more difficult to control, treat, and detailed pathophysiology is unclear. We aimed to compare PI and PD progression utilizing a murine model. MATERIALS AND METHODS: Four-week-old male C57BL/6J mice had their left maxillary molars extracted. Implants were placed in healed extraction sockets and osseointegrated. Ligatures were tied around the implant and second molar...
September 16, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28905475/evaluation-of-volumetric-dimensional-changes-in-posterior-extraction-sites-with-and-without-arp-using-a-novel-imaging-device
#2
Carolina Sbordone, Paolo Toti, Ranieri Martuscelli, Franco Guidetti, Massimo Porzio, Ludovico Sbordone
BACKGROUND: Alveolar ridge volume loss may be minimized when postextraction sockets are filled by bone substitutes. PURPOSE: The aim of the study was to measure the effect of alveolar ridge preservation (ARP) in maintaining the external contour of the ridge after fresh socket grafting with or without particulate anorganic bovine bone mineral (BBM) and resorbable barrier covering. MATERIALS AND METHODS: In the present controlled study, patients subjected to single-tooth extraction were allocated to 2 groups: postextraction sockets grafted with bovine bone mineral (bbm), and naturally healing sockets (nat)...
September 14, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28902422/transplantation-of-non-cultured-stromal-vascular-fraction-cells-of-adipose-tissue-ameliorates-osteonecrosis-of-the-jaw-like-lesions-in-mice
#3
Shinichiro Kuroshima, Muneteru Sasaki, Kazunori Nakajima, Saki Tamaki, Hiroki Hayano, Takashi Sawase
The precise pathoetiology and effective treatment strategies for bisphosphonate-related osteonecrosis of the jaw (BRONJ) remain unknown. Transplantation of non-cultured stromal vascular fraction (SVF) cells has been demonstrated to be a useful method for regenerative medicine in place of stem cell therapy. This study investigated the effects of non-cultured SVF transplantation on tooth extraction socket healing in mice. Both chemotherapeutic/bisphosphonate combination therapy for 7 weeks and tooth extraction of maxillary first molars at 3 weeks after drug administration were performed using female C57BL/6J mice...
September 13, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28895779/combination-of-bone-graft-and-resorbable-membrane-for-alveolar-ridge-preservation-a-systematic-review-meta-analysis-and-trial-sequential-analysis
#4
Giuseppe Troiano, Khrystyna Zhurakivska, Lorenzo Lo Muzio, Luigi Laino, Marco Cicciù, Lucio Lo Russo
INTRODUCTION: Alveolar ridge preservation (ARP) techniques are aimed to reduce the resorption after tooth extraction. The combination of a graft material covered with a resorbable membrane represent one of the most common strategies performed in the clinical practice. The aim of this systematic review was to analyse evidence regarding potential benefits of ARP procedures performed with allogenic/xenogenic grafts in combination with a resorbable membrane coverage in comparison to a spontaneous healing...
September 12, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28885317/ridge-preservation-after-maxillary-third-molar-extraction-using-30-porosity-plga-ha-%C3%AE-tcp-scaffolds-with-and-without-simvastatin-a-pilot-randomized-controlled-clinical-trial
#5
Miguel Noronha Oliveira, Levy Hermes Rau, Aline Marodin, Márcio Corrêa, Letícia Ruhland Corrêa, Aguedo Aragones, Ricardo de Souza Magini
OBJECTIVE: To evaluate clinically and radiographically, in humans, the healing of maxillary third molars postextraction sockets after application of different ridge preservation techniques 3 months after tooth extraction. MATERIALS AND METHODS: Twenty-six sockets (13 patients) were randomly assigned to 4 treatment modalities: deproteinized bovine bone mineral with 10% collagen (DBBM-C), poly(D,L-lactide-co-glycolide) with hydroxyapatite/β-TCP scaffold (PLGA/HA), PLGA/HA/β-TCP with 2...
September 6, 2017: Implant Dentistry
https://www.readbyqxmd.com/read/28880245/evaluation-of-the-healing-potential-of-demineralized-dentin-matrix-fixed-with-recombinant-human-bone-morphogenetic-protein-2-in-bone-grafts
#6
Sang-Yun Kim, Young-Kyun Kim, Yeoung-Hyun Park, Joo-Cheol Park, Jeong-Kui Ku, In-Woong Um, Ji-Yun Kim
We aimed to evaluate the efficacy of demineralized dentin matrix (DDM) fixed with recombinant human bone morphogenetic protein-2 (rhBMP-2) through an experimental and a clinical study. Unilateral upper second and third premolars of eight beagles were extracted. A mucoperiosteal flap was elevated around the extraction socket, and a bone defect was made using a surgical drill. Each DDM was fixed with rhBMP-2, and autogenous bone was grafted at the bone defect area with a collagenous membrane. The beagles were euthanized at two, four, eight, and 12 weeks after receiving the bone graft...
September 7, 2017: Materials
https://www.readbyqxmd.com/read/28861284/alveolar-socket-preservation-with-demineralised-bovine-bone-mineral-and-a-collagen-matrix
#7
Carlo Maiorana, Pier Paolo Poli, Matteo Deflorian, Tiziano Testori, Federico Mandelli, Heiner Nagursky, Raffaele Vinci
PURPOSE: The aim of the present study was to evaluate the healing of post-extraction sockets following alveolar ridge preservation clinically, radiologically, and histologically. METHODS: Overall, 7 extraction sockets in 7 patients were grafted with demineralised bovine bone mineral and covered with a porcine-derived non-crosslinked collagen matrix (CM). Soft tissue healing was clinically evaluated on the basis of a specific healing index. Horizontal and vertical ridge dimensional changes were assessed clinically and radiographically at baseline and 6 months after implant placement...
August 2017: Journal of Periodontal & Implant Science
https://www.readbyqxmd.com/read/28854288/use-of-bone-morphogenetic-protein-2-in-molar-extraction-sockets-for-immediate-implant-placement-a-prospective-case-series
#8
Karl J Zeren
This prospective case series enrolled consecutively qualifying patients that required immediate dental implant placement in large, uncontained, fresh molar extraction sites using recombinant human bone morphogentic protein-2/absorbable collagen sponge (rhBMP-2/ACS) combined with mineralized bone allograft. A total of 11 patients with 15 extraction sites missing bony walls were enrolled for treatment in this prospective case series. The clinical and radiographic effectiveness of rhBMP-2/ACS combined with mineralized bone allograft supported healing of immediately placed implants...
August 30, 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28853203/transcrestal-sinus-floor-augmentation-with-immediate-implant-placement-applied-in-three-types-of-fresh-extraction-sockets-a-clinical-prospective-study-with-1-year-follow-up
#9
Yaqian Chen, Shanshan Yuan, Nan Zhou, Yi Man
BACKGROUND: Immediate implant insertion and transcrestal sinus augmentation both can provide a lot of advantages for patients and clinicians. OBJECTIVE: This prospective study aims to verify the use of a modified technique for immediate implant insertion simultaneously with sinus augmentation in different types of sockets. MATERIALS AND METHODS: Thirty-seven patients were recruited for the clinical study and were divided into 3 groups according to the relationship of their maxillary molar roots and sinus floor: group 1 with none of the teeth roots contacts sinus floor; group 2 as at least 1 teeth root contacting sinus floor, but no root is observed penetrating into sinus cavity; group 3 with at least 1 teeth root penetrating into sinus cavity...
August 29, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28839405/comparative-alveolar-ridge-preservation-using-allogenous-tooth-graft-versus-free-dried-bone-allograft-a-randomized-controlled-prospective-clinical-pilot-study
#10
Chaitanya Pradeep Joshi, Cynthia Bernardo D'Lima, Urmila Chandrashekhar Samat, Prerna Ashok Karde, Agraja Ganpat Patil, Nitin Hemchandra Dani
BACKGROUND: For the first time in India, allografts from human extracted teeth were prepared. A randomized, prospective, clinicoradiographical, histological study was conducted to evaluate their efficacy in comparison with freeze-dried bone allograft (FDBA) in alveolar ridge preservation. MATERIALS AND METHODS: Graft preparation: with written consent, teeth were collected from three donors (full mouth extraction cases). Once donors' serums were tested negative for HIV, HBV, HCV, and Venereal disease research laboratory (VDRL), mineralized whole tooth allograft (WTA) and dentin allograft (DA) were prepared using the standard protocol of Tissue Bank at Tata Memorial Hospital, Mumbai, India...
April 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/28817739/three-dimensional-volumetric-changes-in-severely-resorbed-alveolar-sockets-after-ridge-augmentation-with-bovine-derived-xenograft-and-resorbable-barrier-a-preliminary-study-on-cbct-imaging
#11
Valeria Manavella, Federica Romano, Lisa Corano, Cristina Bignardi, Mario Aimetti
PURPOSE: The primary aim of the study was to describe a novel technique to evaluate volumetric hard tissue dimensional changes after ridge augmentation procedures. The secondary aim was to apply this newly developed measuring method to compromised alveolar sockets grafted with a slowly resorbing biomaterial covered with a collagen membrane. MATERIALS AND METHODS: Eleven patients (6 men and 5 women, mean age 52.7 ± 8.3 years) requiring extraction of one hopeless tooth for severe periodontitis in the maxillary anterior area were consecutively treated with a ridge augmentation procedure...
August 17, 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28817143/clinical-outcomes-of-socket-preservation-using-bovine-derived-xenograft-collagen-and-collagen-membrane-post-tooth-extraction-a-6-month-randomized-controlled-clinical-trial
#12
Vincenzo Iorio-Siciliano, Andrea Blasi, Michele Nicolò, Alessandro Iorio-Siciliano, Francesco Riccitiello, Luca Ramaglia
The aim of this study was to evaluate the clinical remodeling of the alveolar socket following the application of bovine-derived xenograft collagen and collagen membrane compared to natural spontaneous healing during the first 6 months following tooth extraction. A total of 20 patients with 20 fresh alveolar sockets were randomly allocated into a test or control group. After a 6-month follow-up period, surgical reentry was performed and implants were placed. Significant statistical differences were recorded in terms of vertical and horizontal bone changes between the test and control groups...
September 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28795622/animal-models-for-periodontal-tissue-engineering-a-knowledge-generating-process
#13
Karim Mohamed Fawzy El-Sayed, Christof Doerfer
The human periodontium is a uniquely complex vital structure, supporting and anchoring the teeth in their alveolar sockets, playing thereby a decisive role in tooth homeostasis and function. Chronic periodontitis is a highly prevalent immune-inflammatory disease of the periodontium, affecting 15% of adult individuals and is characterized by progressive destruction of the periodontal tooth-investing tissues, culminating in their irreversible damage. Current periodontal evidence-based treatment strategies achieve periodontal healing via repair processes, mostly combating the inflammatory component of the disease, to halt or reduce prospective periodontal tissue loss...
August 10, 2017: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/28770156/platelet-rich-fibrin-in-the-management-of-established-dry-socket
#14
Srinivas Chakravarthi
OBJECTIVES: Dry socket may occur secondary to the removal of any tooth. However, most dry socket cases develop in the third molar region. Dry socket is multifactorial in nature and has been treated using various modalities with varying success rates. This study assessed the efficacy of platelet rich fibrin (PRF) in established dry socket. MATERIALS AND METHODS: Ten patients of either sex aged from 41 to 64 years with established dry socket according to established criteria were treated using PRF...
June 2017: Journal of the Korean Association of Oral and Maxillofacial Surgeons
https://www.readbyqxmd.com/read/28758435/-treating-tissue-defects-following-tooth-removal-three-case-reports
#15
Rita Marton, Anna Martin, Szandra Lemperger, Péter Windisch
Following tooth removal, three dimensional hard- and soft-tissue loss take place. Spontaneous healing makes the defect more severe and results in collapsing tissues. Implant placement is not feasible. In the aestethic zone even fixed partial dentures will not deliver the expected result. Our aim was to demonstrate that only ridge preservation enables implant placement and also provides excellent aestetic result even at frontal areas. CBCT was made before and 6-8 months after ridge preservation. Vertical and socket area measurements were carried out and compared in pre-, and postoperative images...
August 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28744757/six-implant-supported-immediate-fixed-rehabilitation-of-atrophic-edentulous-maxillae-with-tilted-distal-implants
#16
S Wentaschek, S Hartmann, C Walter, W Wagner
BACKGROUND: The aim of this retrospective study was to evaluate the treatment outcome of six Bredent blueSky™ implants (Bredent GmbH, Senden, Germany) immediately loaded with a fixed full-arch prosthesis (two tilted posterior and four axial frontal and premolar implants). METHODS: All 10 patients with atrophic edentulous maxillae being treated with a standardized procedure from 09/2009 to 01/2013, who had a follow-up of at least 3 years, were included. Sixty implants were placed to support 10 screwed prostheses...
December 2017: International Journal of Implant Dentistry
https://www.readbyqxmd.com/read/28744112/strontium-ranelate-treatment-in-a-postmenopausal-woman-with-osteonecrosis-of-the-jaw-after-long-term-oral-bisphosphonate-administration-a-case-report
#17
Whei-Lin Pan, Pi-Lun Chen, Cho-Ying Lin, Yi-Chun Pan, Yuh-Ren Ju, Chiu-Po Chan, Robert Ww Hsu
Bisphosphonates (BPs) suppress bone resorption and increase bone strength, thus reducing the risk of fracture. Oral BPs are widely used for the prevention and treatment of osteoporosis and osteopenia. Here, we describe the case of a postmenopausal woman who took oral alendronate for >3 years for osteoporosis. The patient presented at the clinic with sharp jaw pain and swelling on the left mandible 4 months after extraction of the third molar. Clinical examinations identified an inflamed mucosal opening with pus over an area of necrotic bone...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28739320/immediate-implant-placement-into-posterior-sockets-with-or-without-buccal-bone-dehiscence-defects-a-retrospective-cohort-study
#18
Chen Hu, Ting Gong, Weimin Lin, Quan Yuan, Yi Man
OBJECTIVES: To evaluate bone reconstruction and soft tissue reactions at immediate implants placed into intact sockets and those with buccal bone dehiscence defects. METHODS: Fifty-nine internal connection implants from four different manufacturers were immediately placed in intact sockets(non-dehiscence group, n=40), and in alveoli with buccal bone dehiscence defects: 1) Group 1(n= N10), the defect depth measured 3-5 mm from the gingival margin. 2) Group 2(n=9), the depth ranged from 5mm to 7mm...
July 21, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28727471/cutting-edge-implant-rehabilitation-design-and-management-a-tapered-abutment-approach
#19
Mark Bishara, Gregori M Kurtzman
Immediate implant placement can pose challenges surgically and, ultimately, restoratively. Yet immediate placement has become the standard when adequate bone is present to achieve primary stability and site infection is minimal. To avoid prosthetic complications and ensure the implant is encased in bone after healing, proper planning must consider that implant placement does not necessarily need to follow the trajectory of the root socket. As discussed in this article, maxillary anterior sites have potential issues related to the "triangle of bone" that are not encountered in molar sites and demand different approaches to ensure treatment success...
July 2017: Compendium of Continuing Education in Dentistry
https://www.readbyqxmd.com/read/28727465/clinical-management-of-type-3-recession-defects-with-immediate-implant-and-provisional-restoration-therapy-a-case-report
#20
Dennis P Tarnow, Stephen J Chu
Type 3 extraction sockets present a unique challenge in that they possess gingival recession indicative of facial hard- and soft-tissue loss. When teeth present with prior disease requiring removal and implant replacement, the treatment strategy incorporates palatal implant positioning as well as proper restorative contour management to compensate for the recession defect, thereby allowing the gingival tissues to heal in the correct 3-dimensional position. This article describes the case of a patient with a nonrestorable maxillary right central incisor with internal resorption...
July 2017: Compendium of Continuing Education in Dentistry
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