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Osteoporosis vibration

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https://www.readbyqxmd.com/read/29745538/-low-magnitude-whole-body-vibration-and-postmenopausal-osteoporosis
#1
REVIEW
Huiming Li, Liang Li
Postmenopausal osteoporosis is a type of osteoporosis with high bone transformation rate, caused by a decrease of estrogen in the body, which is a systemic bone disease characterized by decreased bone mass and increased risk of fracture. In recent years, as a kind of non-pharmacologic treatment of osteoporosis, defined by whole-body vibration less than 1 g ( g = 9.81 m/s 2 ), low magnitude whole-body vibration is widely concerned, mainly because of its small side effects, simple operation and relative safety...
April 1, 2018: Sheng Wu Yi Xue Gong Cheng Xue za Zhi, Journal of Biomedical Engineering, Shengwu Yixue Gongchengxue Zazhi
https://www.readbyqxmd.com/read/29626614/effects-of-whole-body-vibration-on-tibia-strength-and-structure-of-competitive-adolescent-swimmers-a-randomized-controlled-trial
#2
Alejandro Gómez-Bruton, Alejandro González-Agüero, Angel Matute-Llorente, Cristina Julián, Gabriel Lozano-Berges, Alba Gómez-Cabello, Nuria Garatachea, Jose A Casajús, German Vicente-Rodríguez
BACKGROUND: Swimming has no effect on bone mass or structure. Therefore, adolescent swimmers present similar bone strength values when compared to normo-active controls, and lower values when compared to weight-bearing athletes. It thus seems necessary to try to improve bone structure and strength of adolescent swimmers through a weight-bearing intervention in order to reduce the risk of suffering osteoporosis later in life. OBJECTIVE: To evaluate the effects of a 6-month WBV intervention on bone strength and structure of adolescent swimmers...
April 4, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29589203/anabolic-therapy-for-the-treatment-of-osteoporosis-in-childhood
#3
REVIEW
Leanne M Ward, Frank Rauch
PURPOSE OF REVIEW: Numerous forms of osteoporosis in childhood are characterized by low bone turnover (for example, osteoporosis due to neuromuscular disorders and glucocorticoid exposure). Anti-resorptive therapy, traditionally used to treat osteoporosis in the young, is associated with further reductions in bone turnover, raising concerns about the long-term safety and efficacy of such therapy. These observations have led to increasing interest in the role of anabolic therapy to treat pediatric osteoporosis...
March 27, 2018: Current Osteoporosis Reports
https://www.readbyqxmd.com/read/29548300/the-combined-effect-of-parathyroid-hormone-1-34-and-whole-body-vibration-exercise-in-the-treatment-of-osteoporosis-pavos-study-protocol-for-a-randomized-controlled-trial
#4
Ditte Beck Jepsen, Jesper Ryg, Niklas Rye Jørgensen, Stinus Hansen, Tahir Masud
BACKGROUND: PaVOS is a randomized controlled trial (RCT) which aims to address the use of whole-body vibration exercise (WBV) in combination with parathyroid hormone 1-34 fragment teriparatide (PTH 1-34) treatment in patients with osteoporosis. PTH 1-34 is an effective but expensive anabolic treatment for osteoporosis. WBV has been found to stimulate muscle and bone growth. Animal studies have shown a beneficial effect on bone when combining PTH 1-34 with mechanical loading. A combined treatment with PTH 1-34 and WBV may potentially have beneficial effects on bone and muscles, and reduce fracture risk...
March 16, 2018: Trials
https://www.readbyqxmd.com/read/29531334/effect-of-high-frequency-loading-and-parathyroid-hormone-administration-on-peri-implant-bone-healing-and-osseointegration
#5
Aya Shibamoto, Toru Ogawa, Joke Duyck, Katleen Vandamme, Ignace Naert, Keiichi Sasaki
The objective of this study is to examine the effect of low-magnitude, high-frequency (LMHF) loading, and anti-osteoporosis medications such as parathyroid hormone (PTH) and bisphosphonates on peri-implant bone healing in an osteoporosis model, and to assess their combined effects on these processes. Thirteen-week-old ovariectomized rats (n = 44) were divided into three groups: PTH, alendronate, and saline. After 3 weeks of drug administration, titanium implants were inserted into the tibiae. Each group was subdivided into two groups: with or without LMHF loading via whole-body vibration (50 Hz at 0...
March 13, 2018: International Journal of Oral Science
https://www.readbyqxmd.com/read/29456437/a-tabletop-persistent-mode-liquid-helium-free-1-5-t-90-mm-mgb-2-finger-mri-magnet-for-osteoporosis-screening-two-design-options
#6
Dongkeun Park, Juan Bascuñán, Philip C Michael, Yukikazu Iwasa
In this paper we present two design options for a tabletop liquid-helium-free, persistent-mode 1.5-T/90-mm MgB2 "finger" MRI magnet for osteoporosis screening. Both designs, one with and the other without an iron yoke, satisfy the following criteria: 1) 1.5-T center field with a 90-mm room-temperature bore for a finger to be placed at the magnet center; 2) spatial field homogeneity of <5 ppm over a 20-mm diameter of spherical volume (DSV); 3) persistent-mode operation with temporal stability of <0...
April 2018: IEEE Transactions on Applied Superconductivity: a Publication of the IEEE Superconductivity Committee
https://www.readbyqxmd.com/read/29354158/effect-of-combined-treatment-with-focused-mechano-acoustic-vibration-and-pharmacological-therapy-on-bone-mineral-density-and-muscle-strength-in-post-menopausal-women
#7
Raoul Saggini, Emilio Ancona, Simona Maria Carmignano, Marco Supplizi, Giovanni Barassi, Rosa Grazia Bellomo
Introduction: Osteoporosis is a systemic disease of the skeleton characterized by a reduction in bone mass and alterations in microarchitecture accompanied by increase in fracture risk, with a relevant decline in quality of life and important social, economic, and health implications, representing one of the most common causes of disability and a major financial item of health cost in many Countries. The best therapy for osteoporosis is prevention, consisting in measures to avoid or slow the onset of the disease...
September 2017: Clinical Cases in Mineral and Bone Metabolism
https://www.readbyqxmd.com/read/29113119/prescribing-physical-activity-for-the-prevention-and-treatment-of-osteoporosis-in-older-adults
#8
REVIEW
Lachlan B McMillan, Ayse Zengin, Peter R Ebeling, David Scott
Osteoporosis is an age-related disease, characterised by low bone mineral density (BMD) and compromised bone geometry and microarchitecture, leading to reduced bone strength. Physical activity (PA) has potential as a therapy for osteoporosis, yet different modalities of PA have varying influences on bone health. This review explores current evidence for the benefits of PA, and targeted exercise regimes for the prevention and treatment of osteoporosis in older adults. In particular, the outcomes of interventions involving resistance training, low- and high-impact weight bearing activities, and whole-body vibration therapy are discussed...
November 6, 2017: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/28982588/low-1-level-mechanical-vibration-improves-bone-microstructure-tissue-mechanical-properties-and-porous-titanium-implant-osseointegration-by-promoting-anabolic-response-in-type-1-diabetic-rabbits
#9
Da Jing, Zedong Yan, Jing Cai, Shichao Tong, Xiaokang Li, Zheng Guo, Erping Luo
Type 1 diabetes mellitus (T1DM) is associated with reduced bone mass, increased fracture risk, and impaired bone defect regeneration potential. These skeletal complications are becoming important clinical challenges due to the rapidly increasing T1DM population, which necessitates developing effective treatment for T1DM-associated osteopenia/osteoporosis and bone trauma. This study aims to investigate the effects of whole-body vibration (WBV), an easy and non-invasive biophysical method, on bone microstructure, tissue-level mechanical properties and porous titanium (pTi) osseointegration in alloxan-diabetic rabbits...
October 2, 2017: Bone
https://www.readbyqxmd.com/read/28760963/atypical-fracture-with-long-term-bisphosphonate-therapy-is-associated-with-altered-cortical-composition-and-reduced-fracture-resistance
#10
Ashley A Lloyd, Bernd Gludovatz, Christoph Riedel, Emma A Luengo, Rehan Saiyed, Eric Marty, Dean G Lorich, Joseph M Lane, Robert O Ritchie, Björn Busse, Eve Donnelly
Bisphosphonates are the most widely prescribed pharmacologic treatment for osteoporosis and reduce fracture risk in postmenopausal women by up to 50%. However, in the past decade these drugs have been associated with atypical femoral fractures (AFFs), rare fractures with a transverse, brittle morphology. The unusual fracture morphology suggests that bisphosphonate treatment may impair toughening mechanisms in cortical bone. The objective of this study was to compare the compositional and mechanical properties of bone biopsies from bisphosphonate-treated patients with AFFs to those from patients with typical osteoporotic fractures with and without bisphosphonate treatment...
August 15, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28743848/-new-methods-for-the-evaluation-of-bone-quality-assessments-of-bone-quality-from-bone-tissues
#11
Shinya Tanaka
Indeed DXA and quantitative CT both which measure bone mineral amount are well established methods to predict bone volume, but some clinical studies say that different rates of bone turnover can cause discrepancies between bone mineral density and bone volume. Bone strength is accused to not only bone mineral density but bone quality, and developments of the osteoporosis drugs have made "bone quality" more important in explaining bone strength. Bone quality refers to architecture, turnover, damage accumulation and mineralization...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28534995/low%C3%A2-level-mechanical-vibration-enhances-osteoblastogenesis-via-a-canonical-wnt-signaling%C3%A2-associated-mechanism
#12
Heqi Gao, Mingming Zhai, Pan Wang, Xuhui Zhang, Jing Cai, Xiaofei Chen, Guanghao Shen, Erping Luo, Da Jing
Osteoporosis is a skeletal metabolic disease characterized by reduced bone mass and a high susceptibility to fractures, in which osteoblasts and osteoclasts are highly involved in the abnormal bone remodeling processes. Recently, low‑magnitude, high‑frequency whole‑body vibration has been demonstrated to significantly reduce osteopenia experimentally and clinically. However, the underlying mechanism regarding how osteoblastic activity is altered when bone tissues adapt to mechanical vibration remains elusive...
July 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28453453/whole-body-vibration-versus-magnetic-therapy-on-bone-mineral-density-in-elderly-osteoporotic-individuals
#13
RANDOMIZED CONTROLLED TRIAL
Alsayed Abdelhameed Shanb, Enas Fawzy Youssef, Qassim Ibrahim Muaidi, Abdullah Ahmed Alothman
BACKGROUND: Osteoporosis usually develops gradually and progresses without significant signs and symptoms. It is one of the most common musculoskeletal conditions associated with aging. OBJECTIVES: To evaluate the effects of whole body vibration (WBV) or magnetic therapy in addition to standard pharmacological treatment on bone mineral density (BMD) in elderly individuals being treated for osteoporosis. METHODS: Eighty-five participants, 60-75 years of age, were randomly divided into three groups...
August 3, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28378291/vibrational-spectroscopic-techniques-to-assess-bone-quality
#14
REVIEW
E P Paschalis, S Gamsjaeger, K Klaushofer
Although musculoskeletal diseases such as osteoporosis are diagnosed and treatment outcome is evaluated based mainly on routine clinical outcomes of bone mineral density (BMD) by DXA and biochemical markers, it is recognized that these two indicators, as valuable as they have proven to be in the everyday clinical practice, do not fully account for manifested bone strength. Thus, the term bone quality was introduced, to complement considerations based on bone turnover rates and BMD. Bone quality is an "umbrella" term that incorporates the structural and material/compositional characteristics of bone tissue...
August 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28338888/vibration-transmission-of-the-spine-during-walking-is-different-between-the-lumbar-and-thoracic-regions-in-older-adults
#15
Dafne Zuleima Morgado Ramirez, Siobhan Strike, Raymond Lee
Background: fractures occur more commonly in the thoracic than in the lumbar spine. Physical activity complemented with pharmacological interventions has been advocated as a preventive measure for osteoporosis. However, walking has been shown to produce only a small improvement in spinal bone mineral density. The characteristics of vibration transmission during walking at the lumbar and thoracic spines may be different, and this may help explain the relative incidence of fractures in the two spine regions...
November 1, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28253368/low-magnitude-high-frequency-vibration-promotes-adipogenic-differentiation-of-bone-marrow-stem-cells-via-p38-mapk-signal
#16
Qian Zhao, Yuezhi Lu, Xueqi Gan, Haiyang Yu
Low magnitude high frequency vibration (LMHFV) has been mainly reported for its influence on the musculoskeletal system, particularly the bone tissue. In the bone structure, osteogenic activity is the main focus of study with regards to LMHFV. However, adipogenesis, another important mode of differentiation in the bone marrow cavity that might be affected by LMHFV, is much less researched. Furthermore, the molecular mechanism of how LMHFV influences adipogenesis still needs to be understood. Here, we tested the effect of LMHFV (0...
2017: PloS One
https://www.readbyqxmd.com/read/28117876/interventions-to-prevent-and-treat-corticosteroid-induced-osteoporosis-and-prevent-osteoporotic-fractures-in-duchenne-muscular-dystrophy
#17
REVIEW
Jennifer M Bell, Michael D Shields, Janet Watters, Alistair Hamilton, Timothy Beringer, Mark Elliott, Rosaline Quinlivan, Sandya Tirupathi, Bronagh Blackwood
BACKGROUND: Corticosteroid treatment is considered the 'gold standard' for Duchenne muscular dystrophy (DMD); however, it is also known to induce osteoporosis and thus increase the risk of vertebral fragility fractures. Good practice in the care of those with DMD requires prevention of these adverse effects. Treatments to increase bone mineral density include bisphosphonates and vitamin D and calcium supplements, and in adolescents with pubertal delay, testosterone. Bone health management is an important part of lifelong care for patients with DMD...
January 24, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28104539/whole-body-vibration-of-mice-induces-progressive-degeneration-of-intervertebral-discs-associated-with-increased-expression-of-il-1%C3%AE-and-multiple-matrix-degrading-enzymes
#18
Matthew R McCann, Matthew A Veras, Cynthia Yeung, Gurkeet Lalli, Priya Patel, Kristyn M Leitch, David W Holdsworth, S Jeffrey Dixon, Cheryle A Séguin
OBJECTIVE: Whole-body vibration (WBV) is a popular fitness trend based on claims of increased muscle mass, weight loss and reduced joint pain. Following its original implementation as a treatment to increase bone mass in patients with osteoporosis, WBV has been incorporated into clinical practice for musculoskeletal disorders, including back pain. However, our recent studies revealed damaging effects of WBV on joint health in a murine model. In this report, we examined potential mechanisms underlying disc degeneration following exposure of mice to WBV...
May 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28031097/effect-of-4-week-whole-body-vibration-on-distal-radius-density
#19
Lei Tan, Yan-Hui Li, Xin Dong, Bin Zhao, Dong Zhu
Objective To assess the effects of high-frequency loading using whole body vibration on distal radius density in adults.Methods The volunteers diagnosed with osteoporosis or osteopenia in the First Hospital of Jilin University from January 2011 to December 2014 were recruited. All the subjects performed foot-based, whole body vibrations on the vibration platform (35 Hz, 0.25 g) once a day, for 15 minutes per session over a period of 4 weeks. The bone mineral density of distal radius (rBMD) was measured using dual-energy X-ray absorptiometry at before, 2-week, and 4-week after the vibration treatment...
June 20, 2016: Chinese Medical Sciences Journal, Chung-kuo i Hsüeh K'o Hsüeh Tsa Chih
https://www.readbyqxmd.com/read/27921147/can-the-alendronate-dosage-be-altered-when-combined-with-high-frequency-loading-in-osteoporosis-treatment
#20
C B Correa, G V Camargos, M Chatterjee, M F Mesquita, A A Del Bel Cury, I Naert, J Duyck, K Vandamme
Alendronate therapy has been associated with serious side effects. Altering the alendronate concentration and combining with high-frequency loading as mechanical intervention was explored in this animal study as a treatment for osteoporosis. The bone anabolic potency of high-frequency loading was overruled by the different alendronate dosages applied in the present study. Further exploration of reduced hormonal therapy associated with mechanical interventions in osteoporosis treatment should be sought. INTRODUCTION: The aim of the present study was to investigate the effect of alendronate (ALN) administration at two different dosages, associated or not with high-frequency (HF) loading, on the bone microstructural response...
April 2017: Osteoporosis International
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