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Osteoporosis vibration

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https://www.readbyqxmd.com/read/28534995/low%C3%A2-level-mechanical-vibration-enhances-osteoblastogenesis-via-a-canonical-wnt-signaling%C3%A2-associated-mechanism
#1
Heqi Gao, Mingming Zhai, Pan Wang, Xuhui Zhang, Jing Cai, Xiaofei Chen, Guanghao Shen, Erping Luo, Da Jing
Osteoporosis is a skeletal metabolic disease characterized by reduced bone mass and a high susceptibility to fractures, in which osteoblasts and osteoclasts are highly involved in the abnormal bone remodeling processes. Recently, low‑magnitude, high‑frequency whole‑body vibration has been demonstrated to significantly reduce osteopenia experimentally and clinically. However, the underlying mechanism regarding how osteoblastic activity is altered when bone tissues adapt to mechanical vibration remains elusive...
July 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28453453/whole-body-vibration-versus-magnetic-therapy-on-bone-mineral-density-in-elderly-osteoporotic-individuals
#2
Alsayed Abdelhameed Shanb, Enas Fawzy Youssef, Qassim Ibrahim Muaidi, Abdullah Ahmed Alothman
BACKGROUND: Osteoporosis usually develops gradually and progresses without significant signs and symptoms. It is one of the most common musculoskeletal conditions associated with aging. OBJECTIVES: To evaluate the effects of whole body vibration (WBV) or magnetic therapy in addition to standard pharmacological treatment on bone mineral density (BMD) in elderly individuals being treated for osteoporosis. METHODS: Eighty-five participants, 60-75 years of age, were randomly divided into three groups...
April 14, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28378291/vibrational-spectroscopic-techniques-to-assess-bone-quality
#3
REVIEW
E P Paschalis, S Gamsjaeger, K Klaushofer
Although musculoskeletal diseases such as osteoporosis are diagnosed and treatment outcome is evaluated based mainly on routine clinical outcomes of bone mineral density (BMD) by DXA and biochemical markers, it is recognized that these two indicators, as valuable as they have proven to be in the everyday clinical practice, do not fully account for manifested bone strength. Thus, the term bone quality was introduced, to complement considerations based on bone turnover rates and BMD. Bone quality is an "umbrella" term that incorporates the structural and material/compositional characteristics of bone tissue...
April 5, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28338888/vibration-transmission-of-the-spine-during-walking-is-different-between-the-lumbar-and-thoracic-regions-in-older-adults
#4
Dafne Zuleima Morgado Ramirez, Siobhan Strike, Raymond Lee
Background: fractures occur more commonly in the thoracic than in the lumbar spine. Physical activity complemented with pharmacological interventions has been advocated as a preventive measure for osteoporosis. However, walking has been shown to produce only a small improvement in spinal bone mineral density. The characteristics of vibration transmission during walking at the lumbar and thoracic spines may be different, and this may help explain the relative incidence of fractures in the two spine regions...
March 18, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28253368/low-magnitude-high-frequency-vibration-promotes-adipogenic-differentiation-of-bone-marrow-stem-cells-via-p38-mapk-signal
#5
Qian Zhao, Yuezhi Lu, Haiyang Yu, Xueqi Gan
Low magnitude high frequency vibration (LMHFV) has been mainly reported for its influence on the musculoskeletal system, particularly the bone tissue. In the bone structure, osteogenic activity is the main focus of study with regards to LMHFV. However, adipogenesis, another important mode of differentiation in the bone marrow cavity that might be affected by LMHFV, is much less researched. Furthermore, the molecular mechanism of how LMHFV influences adipogenesis still needs to be understood. Here, we tested the effect of LMHFV (0...
2017: PloS One
https://www.readbyqxmd.com/read/28117876/interventions-to-prevent-and-treat-corticosteroid-induced-osteoporosis-and-prevent-osteoporotic-fractures-in-duchenne-muscular-dystrophy
#6
REVIEW
Jennifer M Bell, Michael D Shields, Janet Watters, Alistair Hamilton, Timothy Beringer, Mark Elliott, Rosaline Quinlivan, Sandya Tirupathi, Bronagh Blackwood
BACKGROUND: Corticosteroid treatment is considered the 'gold standard' for Duchenne muscular dystrophy (DMD); however, it is also known to induce osteoporosis and thus increase the risk of vertebral fragility fractures. Good practice in the care of those with DMD requires prevention of these adverse effects. Treatments to increase bone mineral density include bisphosphonates and vitamin D and calcium supplements, and in adolescents with pubertal delay, testosterone. Bone health management is an important part of lifelong care for patients with DMD...
January 24, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28104539/whole-body-vibration-of-mice-induces-progressive-degeneration-of-intervertebral-discs-associated-with-increased-expression-of-il-1%C3%AE-and-multiple-matrix-degrading-enzymes
#7
Matthew R McCann, Matthew A Veras, Cynthia Yeung, Gurkeet Lalli, Priya Patel, Kristyn M Leitch, David W Holdsworth, S Jeffrey Dixon, Cheryle A Séguin
OBJECTIVE: Whole-body vibration (WBV) is a popular fitness trend based on claims of increased muscle mass, weight loss and reduced joint pain. Following its original implementation as a treatment to increase bone mass in patients with osteoporosis, WBV has been incorporated into clinical practice for musculoskeletal disorders, including back pain. However, our recent studies revealed damaging effects of WBV on joint health in a murine model. In this report, we examined potential mechanisms underlying disc degeneration following exposure of mice to WBV...
May 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28031097/effect-of-4-week-whole-body-vibration-on-distal-radius-density
#8
Lei Tan, Yan-Hui Li, Xin Dong, Bin Zhao, Dong Zhu
Objective To assess the effects of high-frequency loading using whole body vibration on distal radius density in adults.Methods The volunteers diagnosed with osteoporosis or osteopenia in the First Hospital of Jilin University from January 2011 to December 2014 were recruited. All the subjects performed foot-based, whole body vibrations on the vibration platform (35 Hz, 0.25 g) once a day, for 15 minutes per session over a period of 4 weeks. The bone mineral density of distal radius (rBMD) was measured using dual-energy X-ray absorptiometry at before, 2-week, and 4-week after the vibration treatment...
June 20, 2016: Chinese Medical Sciences Journal, Chung-kuo i Hsüeh K'o Hsüeh Tsa Chih
https://www.readbyqxmd.com/read/27921147/can-the-alendronate-dosage-be-altered-when-combined-with-high-frequency-loading-in-osteoporosis-treatment
#9
C B Correa, G V Camargos, M Chatterjee, M F Mesquita, A A Del Bel Cury, I Naert, J Duyck, K Vandamme
Alendronate therapy has been associated with serious side effects. Altering the alendronate concentration and combining with high-frequency loading as mechanical intervention was explored in this animal study as a treatment for osteoporosis. The bone anabolic potency of high-frequency loading was overruled by the different alendronate dosages applied in the present study. Further exploration of reduced hormonal therapy associated with mechanical interventions in osteoporosis treatment should be sought. INTRODUCTION: The aim of the present study was to investigate the effect of alendronate (ALN) administration at two different dosages, associated or not with high-frequency (HF) loading, on the bone microstructural response...
December 5, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27904420/role-of-the-whole-body-vibration-machine-in-the-prevention-and-management-of-osteoporosis-in-old-age-a-systematic-review
#10
REVIEW
Myint Swe, Biju Benjamin, Aye Aye Tun, Sandheep Sugathan
A literature search of related articles was carried out in electronic data sources. Initially, 276 randomised controlled trials related to the title were collected, after which 44 were selected using the keywords. Overlapping articles, articles with a study duration of less than six months, and studies involving young participants were removed from the list. The remaining 20 articles were checked for entitlement using the PEDro scale. A total of nine eligible articles with 1486 participants were analysed. Seven trials used dual-energy x-ray absorptiometry (DXA) to measure bone mineral density (BMD)...
September 2016: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/27718643/the-effect-of-whole-body-vibration-therapy-on-bone-metabolism-motor-function-and-anthropometric-parameters-in-women-with-postmenopausal-osteoporosis
#11
Xiaotian Luo, Jifeng Zhang, Chi Zhang, Chengqi He, Pu Wang
PURPOSE: To review the research literature on the effectiveness of whole-body vibration (WBV) therapy in women with postmenopausal osteoporosis. METHODS: A systematic review was conducted by two independent reviewers. Mean differences (MDs), standardized mean differences (SMDs), and 95% confidence intervals (CIs) were calculated, and heterogeneity was assessed with the I(2) test. The Cochrane risk of bias tool was used to assess the methodological quality of the selected studies...
October 10, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27609034/effects-of-whole-body-vibration-exercises-on-bone-mineral-density-of-women-with-postmenopausal-osteoporosis-without-medications-novel-findings-and-literature-review
#12
C F Dionello, D Sá-Caputo, H Vfs Pereira, C R Sousa-Gonçalves, A I Maiworm, D S Morel, E Moreira-Marconi, L L Paineiras-Domingos, D Bemben, M Bernardo-Filho
OBJECTIVES: The aim of this study was to review the literature about the effect of whole body vibration exercise in the BMD in patients with postmenopausal osteoporosis without medications. METHODS: A systematic review was performed. RESULTS: The frequency of the mechanical vibration used in the protocols has varied from 12 to 90 Hz. The time used in the protocols varied from 2 up to 22 months. Techniques with X-rays were used in nine of the twelve publications analyzed, the Dual energy X-ray absorptiometry (DEXA) in eight studies and the High resolution peripheral quantitative computed tomography (HR-pQCT) in one publication...
September 7, 2016: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/27311988/the-importance-of-physical-activity-in-osteoporosis-from-the-molecular-pathways-to-the-clinical-evidence
#13
REVIEW
Paola Castrogiovanni, Francesca Maria Trovato, Marta Anna Szychlinska, Houda Nsir, Rosa Imbesi, Giuseppe Musumeci
Osteoporosis is a very common bone disorder characterized by low bone mass and signs of deterioration, responsible for bone fragility typical in this pathology. The risk factors for the onset of osteoporosis are many and different from each other. Some of them cannot be modified, such as age, hereditary diseases and endocrine diseases. Others are modifiable, so that prevention is an advisable tool to reduce the incidence of osteoporosis. Among preventive tools, physical activity is certainly a valid instrument of prevention, in fact physical activity contributes to a healthy energy balance and increases muscle mass and bone mass...
November 2016: Histology and Histopathology
https://www.readbyqxmd.com/read/27272029/the-effect-of-vibration-treatments-combined-with-teriparatide-or-strontium-ranelate-on-bone-healing-and-muscle-in-ovariectomized-rats
#14
M Komrakova, D B Hoffmann, V Nuehnen, H Stueber, M Wassmann, M Wicke, M Tezval, K M Stuermer, S Sehmisch
The aim of the present study was to study the effect of combined therapy of teriparatide (PTH) or strontium ranelate (SR) with whole-body vibration (WBV) on bone healing and muscle properties in an osteopenic rat model. Seventy-two rats (3 months old) were bilaterally ovariectomized (Ovx), and 12 rats were left intact (Non-Ovx). After 8 weeks, bilateral transverse osteotomy was performed at the tibia metaphysis in all rats. Thereafter, Ovx rats were divided into six groups (n = 12): (1) Ovx-no treatment, (2) Ovx + vibration (Vib), (3) SR, (4) SR + Vib, (5) PTH, and (6) PTH + Vib...
October 2016: Calcified Tissue International
https://www.readbyqxmd.com/read/26856338/effects-of-exercise-on-bone-status-in-female-subjects-from-young-girls-to-postmenopausal-women-an-overview-of-systematic-reviews-and-meta-analyses
#15
REVIEW
Jincheng Xu, Giovanni Lombardi, Wei Jiao, Giuseppe Banfi
BACKGROUND: Osteoporosis and postmenopausal bone loss pose a huge social and economic burden worldwide. Regular exercise and physical activity are effective interventions for maximizing or maintaining peak bone mass and preventing bone loss in the elderly; however, most recommendations are addressed to the general public and lack specific indications for girls and women, the segment of the population most at risk for developing osteoporosis. OBJECTIVE: The aim of this overview of systematic reviews and meta-analyses was to summarize current evidence for the effects of exercise and physical activity interventions on bone status in girls and women, and to explore whether specific exercise programs exist for improving or maintaining bone mass or bone strength in females...
August 2016: Sports Medicine
https://www.readbyqxmd.com/read/26825660/comparison-of-parathyroid-hormone-and-strontium-ranelate-in-combination-with-whole-body-vibration-in-a-rat-model-of-osteoporosis
#16
COMPARATIVE STUDY
D B Hoffmann, S Sehmisch, A M Hofmann, C Eimer, M Komrakova, D Saul, M Wassmann, K M Stürmer, M Tezval
We investigated the combinatorial effects of whole-body vertical vibration (WBVV) with the primarily osteoanabolic parathyroid hormone (PTH) and the mainly antiresorptive strontium ranelate (SR) in a rat model of osteoporosis. Ovariectomies were performed on 76 three-month-old Sprague-Dawley rats (OVX, n = 76; NON-OVX, n = 12). After 8 weeks, the ovariectomized rats were divided into 6 groups. One group (OVX + PTH) received daily injections of PTH (40 µg/kg body weight/day) for 6 weeks. Another group (OVX + SR) was fed SR-supplemented chow (600 mg/kg body weight/day)...
January 2017: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/26746476/effect-of-concurrent-use-of-whole-body-vibration-and-parathyroid-hormone-on-bone-structure-and-material-properties-of-ovariectomized-mice
#17
Takeshi Matsumoto, Shinya Itamochi, Yoshihiro Hashimoto
This study was designed to determine the effectiveness of whole-body vibration (WBV) and intermittent parathyroid hormone (iPTH) in combination against estrogen deficiency-induced osteoporosis. Female C57BL/6J mice were bilaterally ovariectomized (OVX, n = 40) or sham-operated (sham-OVX, n = 8) at 9 weeks of age. Two weeks later, the OVX mice were randomly divided into four groups (n = 10 each): the control group (c-OVX) and groups treated with iPTH (p-OVX), WBV (w-OVX) and both (pw-OVX). The p-OVX and pw-OVX groups were given human PTH (1-34) at a dose of 30 µg/kg/day...
2016: Calcified Tissue International
https://www.readbyqxmd.com/read/26662723/administration-duration-influences-the-effects-of-low-magnitude-high-frequency-vibration-on-ovariectomized-rat-bone
#18
Fangzhu Qing, Pengfei Xie, Yacincha Selushia Liem, Ying Chen, Xuening Chen, Xiangdong Zhu, Yujiang Fan, Xiao Yang, Xingdong Zhang
Low-magnitude, high-frequency vibration (LMHFV) has been proposed as a non-drug anti-osteoporosis treatment. However, the influence of administration duration on its effect is seldom investigated. In this study, the effect of 16-week LMHFV (0.3 g, 30 Hz, 20 min/day) on the bone mineral densities (BMDs), bone mechanical properties, and cellular responses of osteoporotic and healthy rats was examined by in vivo peripheral quantitative computed tomography (pQCT), fracture tests, cell assays, and mRNA quantification...
July 2016: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/26647791/whole-body-vibration-improves-fracture-healing-and-bone-quality-in-rats-with-ovariectomy-induced-osteoporosis
#19
Mariana Maloste Butezloff, Ariane Zamarioli, Graziela Bianchi Leoni, Manoel Damião Sousa-Neto, Jose Batista Volpon
PURPOSE: To investigate the effect of vibration therapy on the bone callus of fractured femurs and the bone quality of intact femurs in ovariectomized rats. METHODS: Fifty-six rats aged seven weeks were divided into four groups: control with femoral fracture (CON, n=14), ovariectomized with femoral fracture (OVX, n=14), control with femoral fracture plus vibration therapy (CON+VT, n=14), and ovariectomized with femoral fracture plus vibration therapy (OVX+VT, n=14)...
November 2015: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/26539896/evidence-of-altered-matrix-composition-in-iliac-crest-biopsies-from-patients-with-idiopathic-juvenile-osteoporosis
#20
Ignacio Garcia, Vincent Chiodo, Yan Ma, Adele Boskey
PURPOSE: Idiopathic juvenile osteoporosis (IJO) is a rare condition in children, characterized by bone pain and long bone and vertebral fractures. Previously, IJO bone was solely characterized by histomorphometry and quantitative computed tomography. The goal of this study is to describe IJO bone composition. MATERIALS AND METHODS: Fourier transform infrared imaging (FTIRI), a vibrational spectroscopic technique providing spatially resolved images of chemical composition, was used to determine whether iliac crest biopsies from children with IJO differed in composition from and age- and sex-matched controls, and, as a secondary analysis, whether IJO bone showed the same disease dependent change in composition as do iliac crest bone biopsies from women with post-menopausal osteoporosis (PMO)...
2016: Connective Tissue Research
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