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Brian M Ilfeld
A continuous peripheral nerve block (CPNB) consists of a percutaneously inserted catheter with its tip adjacent to a target nerve/plexus through which local anesthetic may be administered, providing a prolonged block that may be titrated to the desired effect. In the decades after its first report in 1946, a plethora of data relating to CPNB was published, much of which was examined in a 2011 Anesthesia & Analgesia article. The current update is an evidence-based review of the CPNB literature published in the interim...
October 3, 2016: Anesthesia and Analgesia
Ahmed R Eldesoky, Esben S Yates, Tine B Nyeng, Mette S Thomsen, Hanne M Nielsen, Philip Poortmans, Carine Kirkove, Mechthild Krause, Claus Kamby, Ingvil Mjaaland, Egil S Blix, Ingelise Jensen, Martin Berg, Ebbe L Lorenzen, Zahra Taheri-Kadkhoda, Birgitte V Offersen
BACKGROUND AND PURPOSE: To internally and externally validate an atlas based automated segmentation (ABAS) in loco-regional radiation therapy of breast cancer. MATERIALS AND METHODS: Structures of 60 patients delineated according to the ESTRO consensus guideline were included in four categorized multi-atlas libraries using MIM Maestro™ software. These libraries were used for auto-segmentation in two different patient groups (50 patients from the local institution and 40 patients from other institutions)...
September 30, 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
Pauliina Wright, Sami Suilamo, Paula Lindholm, Jarmo Kulmala
BACKGROUND: In postmastectomy radiotherapy (PMRT), the dose coverage of the planning target volume (PTV) with additional margins, including the chest wall, supraclavicular, interpectoral, internal mammary and axillar level I-III lymph nodes, is often compromised. Electron fields may improve the medial dose coverage while maintaining organ at risk (OAR) doses at an acceptable level, but at the cost of hot and cold spots at the electron and photon field junction. To improve PMRT dose coverage and uniformity, an isocentric technique combining tangential intensity-modulated (IM)RT fields with one medial electron field was implemented...
August 2014: Acta Oncologica
M Wallaert, P Courivaud, E-H Mati, M Shiniara, J-M Guilbert
We describe the case of four patients who had undergone breast surgery. The post-operative analgesia consisted in levobupivacaine administered through a catheter placed between the pectoralis minor and the pectoralis major using ultrasound guided technique. The quality of the analgesia was excellent quality. No side-effects were encountered.
April 2014: Annales Françaises D'anesthèsie et de Rèanimation
Alfredo Carlos S D Barros, Felipe Eduardo M Andrade, José Luiz B Bevilacqua, Maria Aparecida C Barros, José Roberto Piato, Donizeti R Santos, José Roberto Filassi, Cristiane C B A Nimir
AIMS AND BACKGROUND: The extent of axillary lymph node dissection for breast cancer treatment is tailored to each patient. When the surgeon assumes that full dissection, including level III, is needed, there are basically two ways for reaching the apical nodes while preserving the pectoralis muscles: a subpectoral approach, below the joined pectoralis muscles, and another that includes an additional interpectoral dissection between the muscles. We conducted a study to evaluate the radicality of dissection using these two approaches...
July 2013: Tumori
Jin Kyoung Oh, Yong An Chung, Yeon Sil Kim, Hae Myung Jeon, Sung Hoon Kim, Young Ha Park, Soo Kyo Chung
We assessed the role of F-18 FDG PET/CT in evaluating isolated extra-axillary lymph node recurrences in postoperative breast cancer patients and its prognostic value on clinical outcome. We reviewed PET/CT scans of postoperative breast cancer patients performed at our institution between July 2003 and February 2012. We recorded PET/CT findings, clinicopathologic variables and treatment modalities. We analyzed metabolic parameters from PET/CT and clinicopathologic variables with respect to progression free survival (PFS)...
2014: Bio-medical Materials and Engineering
Pedro Coelho Barata, Joana Morgado, Ana Paula Sousa, Sónia Duarte de Oliveira, Maria Paula Custódio, Lígia Bruno da Costa, José Esteves Pena
BACKGROUND: Paraneoplastic neurologic syndromes (PNS) pose quite an uncommon neurological complication, affecting less than 1% of patients with breast cancer. Nearly one third of these patients lack detectable onconeural antibodies (ONAs), and improvement in neurologic deficits with concomitant cancer treatments is achieved in less than 30% of cases. CASE PRESENTATION: A 42-year-old, premenopausal woman presented with facial paralysis on the central left side accompanied by a left tongue deviation, an upward vertical nystagmus, moderate spastic paraparesis, dystonic posturing of the left foot, lower limb hyperreflexia and bilateral extensor plantar reflex...
September 2012: Case Reports in Oncology
O R Brouwer, L Vermeeren, I M C van der Ploeg, R A Valdés Olmos, C E Loo, L M Pereira-Bouda, F Smit, P Neijenhuis, B C Vrouenraets, F Sivro-Prndelj, S M Jap-a-Joe, P J Borgstein, E J Th Rutgers, H S A Oldenburg
PURPOSE: To investigate whether lymphoscintigraphy and SPECT/CT after intralesional injection of radiopharmaceutical into each tumour separately in patients with multiple malignancies in one breast yields additional sentinel nodes compared to intralesional injection of the largest tumour only. METHODS: Patients were included prospectively at four centres in The Netherlands. Lymphatic flow was studied using planar lymphoscintigraphy and SPECT/CT until 4 h after administration of (99m)Tc-nanocolloid in the largest tumour...
July 2012: European Journal of Nuclear Medicine and Molecular Imaging
Jingyan Sun, Jian Yin, Liansheng Ning, Juntian Liu, Hong Liu, Lin Gu, Li Fu
OBJECTIVE: The presence of discontinuous or "skip" metastases in breast cancer is crucial for determining the optimal therapeutic choice. In this study, we compared the clinicopathological characteristics and prognosis of patients with or without skip metastases (SMs). METHODS: We retrospectively analyzed the records of 1,502 breast cancer patients who underwent radical mastectomy and a separate group of 118 patients who had sentinel lymph node biopsies (SLNB). The median follow-up time was 10 years...
February 2012: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
Evan I Blumgart, Roger F Uren, Poul M F Nielsen, Martyn P Nash, Hayley M Reynolds
Detailed knowledge of the lymphatic drainage of the breast is limited. Lymphoscintigraphy is a technique used during breast cancer treatment to accurately map patterns of lymphatic drainage from the primary tumour to the draining lymph nodes. This study aimed to create a statistical model to analyse the spread of breast cancer and primary tumour location using a large lymphoscintigraphy database, and visualise the results with a novel computational model. This study was based on lymphoscintigraphy data from 2,304 breast cancer patients treated at the Royal Prince Alfred Hospital Medical Centre in Sydney, Australia...
November 2011: Breast Cancer Research and Treatment
Il Ki Hong, Deog Yoon Kim
We report F-18 FDG PET/CT images of biopsy-proven intramuscular metastasis from primary uterine cervix cancer. A 70-year-old woman was admitted because of a mass in the left axilla. She was diagnosed with uterine cervix cancer and underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy, and pelvic node dissection and received adjuvant chemotherapy and radiation therapy 9 years ago. Magnetic resonance imaging showed a large soft tissue mass in the intramuscular region of the left axilla. The mass showed intense F-18 FDG uptake with a central necrotic portion on F-18 FDG PET/CT...
June 2011: Clinical Nuclear Medicine
Tjeerd S Aukema, Marieke E Straver, Marie-Jeanne T F D Vrancken Peeters, Nicola S Russell, Kenneth G A Gilhuijs, Wouter V Vogel, Emiel J T Rutgers, Renato A Valdés Olmos
PURPOSE: The aim of this prospective study was to assess the incidence of extra-axillary lymph node involvement on baseline FDG PET/CT in patients with stage II-III breast cancer scheduled for neo-adjuvant chemotherapy. METHODS: Patients with invasive breast cancer of >3 cm and/or proven axillary lymph node metastasis were included for before neo-adjuvant chemotherapy. Baseline ultrasound of the infra- and supraclavicular regions was performed with fine-needle biopsy as needed...
December 2010: European Journal of Cancer
A Bricou, Y Delpech, E Barranger
No abstract text is available yet for this article.
February 2010: Gynécologie, Obstétrique & Fertilité
Kenichi Sakurai, Shigeru Fujisaki, Sadanori Matsuo, Michitaka Ogura, Katsuhisa Enomoto, Akira Kitajima, Mayumi Tani, Sadao Amano, Motomi Shiono
We report a case of advanced breast cancer with skin ulceration and bleeding (T4bN3bM0, Stage IIIC) achieving a significant improvement of QOL by paclitaxel (PTX) and toremifene (TOR) therapy. The patient was a 31-year-old woman who had ulcerative breast lump with skin ulcer. A core needle biopsy for breast tumor led to a diagnosis of an invasive ductal carcinoma positive for estrogen receptor and progesterone receptor, and negative for HER2/neu protein expression. She received 4 courses of tri-weekly CEF (C: 500 mg, E: 60 mg, F: 500 mg/m2/tri-weekly) and 4 courses of weekly PTX (80 mg/m2) with TOR (120 mg/day)...
November 2009: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Y M Kirova, P Castro Pena, R Dendale, F Campana, M A Bollet, N Fournier-Bidoz, A Fourquet
PURPOSE: To assist in the determination of breast and nodal volumes in the setting of radiotherapy for breast cancer and establish segmentation guidelines. Materials and methods. Contrast metarial enhanced CT examinations were obtained in the treatment position in 25 patients to clearly define the target volumes. The clinical target volume (CTV) including the breast, internal mammary nodes, supraclavicular and subclavicular regions and axxilary region were segmented along with the brachial plexus and interpectoral nodes...
June 2009: Journal de Radiologie
Alejandro Andrés, Leticia Tardín, Paula Razola, Albert Santapau, Enrique Prats, Ramon Sousa, Fausto García, Javier Banzo
A 57-year-old woman with infiltrating ductal carcinoma of the right breast underwent lymph node scintigraphy with Tc-99m-nanocolloid for preoperative sentinel node localization. On planar images, an unusual pattern of lymphatic drainage was observed. We performed a chest SPECT/CT, revealing an interpectoral sentinel node, ie, Rotter's node. The patient underwent radioguided surgery and the sentinel node was located intraoperatively, and found to be disease-free. SPECT/CT fusion techniques have enhanced precision in locating sentinel nodes, enabling the surgeon to shorten surgical times...
March 2009: Clinical Nuclear Medicine
Kenichi Sakurai, Katsuhisa Enomoto, Mayumi Tani, Akira Kitajima, Sadao Amano, Motomi Shiono
We report a case of advanced breast cancer with skin ulceration and bleeding (T4bN3bM0: Stage IIIC) achieving a significant improvement of QOL by toremifene and paclitaxel therapy. The patient was a 38-year-old woman with slight anemia who had ulcerative breast lump with skin ulcer. A core needle biopsy for breast tumor led to a diagnosis of an invasive ductal carcinoma positive for estrogen receptor and progesteron receptor, and negative for HER2/neu protein expression. She received 6 cycles of tri-weekly FEC (C: 500 mg, E: 60 mg, F: 500 mg/m2) and 16 cycles of weekly paclitaxel (80 mg/m2) with toremifene (120 mg/day)...
November 2008: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Jing-Yan Sun, Lian-Sheng Ning
OBJECTIVE: To analyze the clinicopathologic characteristics and the prognostic factors of breast cancer patients with skip metastases in the axilla. METHODS: The clinical data of 1502 breast cancer patients who underwent complete axillary lymph node dissection were retrospectively reviewed. The patterns of skip metastases, clinical features and prognostic factors were analyzed. RESULTS: Of the 1502 patients, lymph node metastases were found in 814, of whom skip metastases in 119 (14...
May 2008: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
Gertrude M Beer, Andrew Manestar, Mirjana Manestar
Despite the great number of pedicled and free flaps that are available for defect and contour repair, the number of fascia flaps with an axial blood supply are sparse. Such flaps with their gliding function are mandatory, whenever coverage with very thin, well-vascularized tissue is necessary. To the currently established fascia flaps, (the temporoparietal fascia flap, the radial forearm fascia flap, the lateral arm fascia flap, and the serratus anterior fascia flap), we want to add a new fascia flap, the interpectoral fascia flap...
September 2008: Clinical Anatomy
Dae Jung Kim, Eun Ju Son, Soon Won Hong, Eun-Kyung Kim, Jin Young Kwak, Ki Keun Oh, Joon Jeong
No abstract text is available yet for this article.
March 2008: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
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