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https://www.readbyqxmd.com/read/28921659/ligature-induced-peri-implantitis-and-periodontitis-in-mice
#1
Sarah Hiyari, Ryan Wong, Aline Yaghsezian, Azadi Naghibi, Sotirios Tetradis, Paulo M Camargo, Flavia Q Pirih
AIM: Peri-implantitis (PI), inflammation around dental implants, shares characteristics with periodontitis (PD). However, PI is more difficult to control, treat, and detailed pathophysiology is unclear. We aimed to compare PI and PD progression utilizing a murine model. MATERIALS AND METHODS: Four-week-old male C57BL/6J mice had their left maxillary molars extracted. Implants were placed in healed extraction sockets and osseointegrated. Ligatures were tied around the implant and second molar...
September 16, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28901013/how-active-are-young-cardiac-device-patients-objective-assessment-of-activity-in-children-with-cardiac-devices
#2
Caridad M de la Uz, Ashley E Burch, Bruce Gunderson, Jodi Koehler, Samuel F Sears
BACKGROUND: The daily activity of pediatric patients with implantable cardiac devices provides behavioral evidence of functional outcomes. Modern devices provide continuous accelerometer data that is sensitive to movement, but normative values have not been published for pediatric activity rates. This study provides the first normative accelerometer data on activity rates in a large sample of pediatric cardiac device patients. METHODS: Patients were between 3 and 18 years old, (N = 1,905) and implanted with a cardiac device from a single device company, and enrolled in remote monitoring...
September 12, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28861284/alveolar-socket-preservation-with-demineralised-bovine-bone-mineral-and-a-collagen-matrix
#3
Carlo Maiorana, Pier Paolo Poli, Matteo Deflorian, Tiziano Testori, Federico Mandelli, Heiner Nagursky, Raffaele Vinci
PURPOSE: The aim of the present study was to evaluate the healing of post-extraction sockets following alveolar ridge preservation clinically, radiologically, and histologically. METHODS: Overall, 7 extraction sockets in 7 patients were grafted with demineralised bovine bone mineral and covered with a porcine-derived non-crosslinked collagen matrix (CM). Soft tissue healing was clinically evaluated on the basis of a specific healing index. Horizontal and vertical ridge dimensional changes were assessed clinically and radiographically at baseline and 6 months after implant placement...
August 2017: Journal of Periodontal & Implant Science
https://www.readbyqxmd.com/read/28843033/hemodynamic-analysis-of-a-novel-bioresorbable-scaffold-in-porcine-coronary-artery-model
#4
Erhan Tenekecioglu, Ryo Torii, Christos V Bourantas, Rafael Cavalcante, Yohei Sotomi, Yaping Zeng, Carlos Collet, Tom Crake, Alexandre Abizaid, Yoshinobu Onuma, Solomon Su, Teguh Santoso, Patrick W Serruys
BACKGROUND: The shear stress distribution assessment can provide useful insights for the hemodynamic performance of the implanted stent/scaffold. Our aim was to investigate the effect of a novel bioresorbable scaffold, Mirage on local hemodynamics in animal models. METHOD: The main epicardial coronary arteries of 7 healthy mini-pigs were implanted with 11 Mirage Microfiber sirolimus-eluting Bioresorbable Scaffolds (MMSES). Optical coherence tomography (OCT) was performed post scaffold implantation and the obtained images were fused with angiographic data to reconstruct the coronary artery anatomy...
August 26, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28822408/-the-application-of-artificial-neural-network-on-the-assessment-of-lexical-tone-production-of-pediatric-cochlear-implant-users
#5
Y T Mao, Z M Chen, L Xu
Objective: The present study was carried out to explore the tone production ability of the Mandarin-speaking children with cochlear implants (CI) by using an artificial neural network model and to examine the potential contributing factors underlining their tone production performance. The results of this study might provide useful guidelines for post-operative rehabilitation processes of pediatric CI users. Methods: Two hundred and seventy-eight prelingually deafened children who received unilateral CI participated in this study...
August 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28817143/clinical-outcomes-of-socket-preservation-using-bovine-derived-xenograft-collagen-and-collagen-membrane-post-tooth-extraction-a-6-month-randomized-controlled-clinical-trial
#6
Vincenzo Iorio-Siciliano, Andrea Blasi, Michele Nicolò, Alessandro Iorio-Siciliano, Francesco Riccitiello, Luca Ramaglia
The aim of this study was to evaluate the clinical remodeling of the alveolar socket following the application of bovine-derived xenograft collagen and collagen membrane compared to natural spontaneous healing during the first 6 months following tooth extraction. A total of 20 patients with 20 fresh alveolar sockets were randomly allocated into a test or control group. After a 6-month follow-up period, surgical reentry was performed and implants were placed. Significant statistical differences were recorded in terms of vertical and horizontal bone changes between the test and control groups...
September 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28814631/face-percept-formation-in-human-ventral-temporal-cortex
#7
Kai J Miller, Dora Hermes, Franco Pestilli, Gagan S Wig, Jeffrey G Ojemann
Loci in ventral temporal cortex are selectively active while viewing faces and other objects, but it remains unclear whether these areas represent accumulation of simple visual information, or processing of intact percept. We measured broadband electrocorticographic changes from implanted electrodes on the ventral temporal brain surface while showing patients noise-degraded images of faces and houses. In a subset of posterior fusiform gyrus face-selective regions, cortical activity decreased parametrically with noise increase, until the perceptual threshold...
August 16, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28807525/experimental-and-computational-analysis-of-micromotions-of-an-uncemented-femoral-knee-implant-using-elastic-and-plastic-bone-material-models
#8
Sanaz Berahmani, Dennis Janssen, Nico Verdonschot
It is essential to calculate micromotions at the bone-implant interface of an uncemented femoral total knee replacement (TKR) using a reliable computational model. In the current study, experimental measurements of micromotions were compared with predicted micromotions by Finite Element Analysis (FEA) using two bone material models: linear elastic and post-yield material behavior, while an actual range of interference fit was simulated. The primary aim was to investigate whether a plasticity model is essential in order to calculate realistic micromotions...
July 29, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28799565/modified-technique-of-endocapsular-lens-aspiration-for-severely-subluxated-lenses
#9
S Khokhar, N Aron, N Yadav, G Pillay, E Agarwal
PurposeSeverely subluxated crystalline lenses pose a difficult situation to anterior segment surgeons and can only be managed surgically by removal of the lens as well as the capsular bag. Several techniques have been described in literature for the management of such cases. We describe a modified technique of endocapsular lens aspiration by the limbal route for lens extraction through small incisions on the cornea.Patients and methodsThirty-two eyes of 16 consecutive patients with severely subluxated crystalline lenses were recruited in the study...
August 11, 2017: Eye
https://www.readbyqxmd.com/read/28760213/retained-cardiac-implantable-electronic-device-fragments-are-not-associated-with-magnetic-resonance-imaging-safety-issues-morbidity-or-mortality-after-orthotopic-heart-transplant
#10
Christopher O Austin, Kevin Landolfo, Pragnesh P Parikh, Parag C Patel, K L Venkatachalam, Fred M Kusumoto
BACKGROUND: Cardiac implantable electronic device therapy (CIED) has revolutionized treatment for advanced heart failure. Most patients considered for orthotopic heart transplantation (OHT) are treated with implantable cardioverter defibrillators, cardiac resynchronization therapy, or both. These CIEDs are surgically extracted at the time of transplant. Occasionally, CIEDs are incompletely removed. Little is known about the outcomes of post-OHT patients with retained CIED fragments. METHODS: We identified 200 consecutive patients that underwent OHT at our institution between April 2006 and December 2014 and performed a retrospective analysis of available radiographic images and clinical records...
August 2017: American Heart Journal
https://www.readbyqxmd.com/read/28744958/post-extraction-implant-placement-into-infected-versus-non-infected-sites-a-multicenter-retrospective-clinical-study
#11
Francesco Zuffetti, Matteo Capelli, Fabio Galli, Massimo Del Fabbro, Tiziano Testori
PURPOSE: The aim of this study was to assess whether immediate implant placement into post-extraction sites presenting a chronic infection poses a greater risk of implant failure than immediate placement in non-infected sites. MATERIALS AND METHODS: Records of patients who underwent extraction and immediate implant placement into both infected and non-infected sites from January 1998 to September 2014 at 5 different dental centers were considered for inclusion. Included records were subjected to statistical analysis of survival rates, along with a number of other patient-, implant-, surgery-, and prosthesis-related variables...
July 26, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28728260/-clinical-analysis-of-pacing-therapy-and-treatment-of-complications-during-follow-up-in-children
#12
P J Zhao, Y W Chen, F Li, Y Li, J P Yang, J J Wu
Objective: To analyze characteristics of permanent pacemaker implantation in children as well as treatment and prognosis of complications. Method: Clinical data of children who underwent endocardial or epicardial permanent pacemaker implantation between April 2000 and June 2016 in Shanghai Xinhua Hospital and Shanghai Children's Medical Center were analyzed retrospectively. These patients were discharged 5 days after implantation. Electrocardiogram, chest X ray, echocardiography and pacemaker programming were performed during follow-up...
July 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28727672/cardiac-rehabilitation-in-patients-with-left-ventricular-assist-device-a-systematic-review-and-meta-analysis
#13
Toufik Mahfood Haddad, Alok Saurav, Aiman Smer, Muhammad S Azzouz, Abhilash Akinapelli, Mark A Williams, Venkata M Alla
PURPOSE: Exercise-based cardiac rehabilitation (EBCR) has been demonstrated to improve functional capacity in heart failure (HF). However, there are limited data on the effect of EBCR in patients with advanced HF and left ventricular assist devices (LVADs). This meta-analysis sought to evaluate the effects of EBCR on functional capacity in patients with LVAD. METHODS: PubMed, Web of Science, CINAHL, and Cochrane Library databases were searched for randomized studies assessing the impact of EBCR in patients following LVAD implantation compared with standard therapy (ST)...
July 19, 2017: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/28713017/intracellular-co-delivery-of-sr-ion-and-phenamil-drug-through-mesoporous-bioglass-nanocarriers-synergizes-bmp-signaling-and-tissue-mineralization
#14
Jung-Hwan Lee, Nandin Mandakhbayar, Ahmed El-Fiqi, Hae-Won Kim
Inducing differentiation and maturation of resident multipotent stem cells (MSCs) is an important strategy to regenerate hard tissues in mal-calcification conditions. Here we explore a co-delivery approach of therapeutic molecules comprised of ion and drug through a mesoporous bioglass nanoparticle (MBN) for this purpose. Recently, MBN has offered unique potential as a nanocarrier for hard tissues, in terms of high mesoporosity, bone bioactivity (and possibly degradability), tunable delivery of biomolecules, and ionic modification...
July 14, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28709673/stereophotogrammetric-impression-making-for-polyoxymethylene-milled-immediate-partial-fixed-dental-prostheses
#15
Miguel Gómez-Polo, Cristina Gómez-Polo, Jaime Del Río, Rocío Ortega
Immediate post-extraction and same-day placement of interim prostheses have increased patient acceptance of implant-supported prostheses. However, for immediate prostheses supported by multiple implants, meeting passive fit and esthetic standards is often challenging. In this clinical report, implant photogrammetry was combined with conventionally obtained digitized casts to prepare an interim, milled prosthesis from a polyoxymethylene (POM) disk, using computer-aided design and computer-aided manufacturing techniques...
July 11, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28691480/computer-guided-implant-insertion-in-a-patient-with-impacted-maxillary-canines-case-report
#16
S Lico, C Andrisani, M Andreasi Bassi, V Candotto, F J Silvestre, D Lauritano
The use of minimally invasive surgical techniques undoubtedly represents a huge advantage for both the clinician and the patient. This case report shows the possibility of making an implant-prosthetic rehabilitation in an upper jaw in a patient who presented dental elements 1.3 and 2.3 in bone inclusion. The use of computer-guided surgery offers us the possibility to carry out this type of implant rehabilitation without performing the extraction of the above-mentioned dental elements combined with the bone regeneration of the extraction sockets...
April 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28684441/structural-valve-deterioration-after-transcatheter-aortic-valve-implantation
#17
Farid Foroutan, Gordon H Guyatt, Catherine M Otto, Reed A Siemieniuk, Stefan Schandelmaier, Thomas Agoritsas, Per O Vandvik, Sai Bhagra, Rodrigo Bagur
BACKGROUND: Transcatheter aortic valve implantation (TAVI), widely used to treat high-risk patients with severe symptomatic aortic stenosis, has recently been extended to younger patients at lower operative risk in whom long-term durability of TAVI devices is an important concern. Therefore, we conducted a systematic review and meta-analysis of observational studies addressing the frequency of structural valve deterioration (SVD) after TAVI. METHODS: We searched Medline, Embase, Cochrane Database of Systematic Reviews, and Cochrane CENTRAL from 2002 to September 2016...
July 6, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28668263/meta-analysis-of-predictors-of-early-severe-bleeding-in-patients-who-underwent-transcatheter-aortic-valve-implantation
#18
REVIEW
Yinghao Sun, Xianbao Liu, Zexin Chen, Jiaqi Fan, Jubo Jiang, Yuxin He, Qifeng Zhu, Po Hu, Lihan Wang, Qiyuan Xu, Xiaoping Lin, Jian'an Wang
Severe bleeding (SB) in patients who underwent transcatheter aortic valve implantation (TAVI) could be fatal. Although multiple independent predictors of bleeding post-TAVI have been identified, the definitions of bleeding and predictors vary across studies. This study aimed to provide summary effect estimates for predictors of SB within 30 days post-TAVI. A systematic review of studies that reported the incidence of bleeding post-TAVI with raw data for predictors of interest was performed. Data on characteristics of study, patient, and procedure were extracted...
August 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28666883/a-macroporous-heparin-releasing-silk-fibroin-scaffold-improves-islet-transplantation-outcome-by-promoting-islet-revascularisation-and-survival
#19
Duo Mao, Meifeng Zhu, Xiuyuan Zhang, Rong Ma, Xiaoqing Yang, Tingyu Ke, Lianyong Wang, Zongjin Li, Deling Kong, Chen Li
Islet transplantation is considered the most promising therapeutic option with the potential to cure diabetes. However, efficacy of current clinical islet transplantation is limited by long-term graft dysfunction and attrition. We have investigated the therapeutic potential of a silk fibroin macroporous (SF) scaffold for syngeneic islet transplantation in diabetic mice. The SF scaffold was prepared via lyophilisation, which enables incorporation of active compounds including cytokines, peptide and growth factors without compromising their biological activity...
September 1, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28643222/ridge-preservation-using-an-in-situ-hardening-biphasic-calcium-phosphate-%C3%AE-tcp-ha-bone-graft-substitute-a-clinical-radiological-and-histological-study
#20
Ashish Kakar, Bappanadu H Sripathi Rao, Shashikanth Hegde, Nikhil Deshpande, Annette Lindner, Heiner Nagursky, Aditya Patney, Harsh Mahajan
BACKGROUND: Post-Extraction ridge preservation using bone graft substitutes is a conservative technique to maintain the width of the alveolar ridge. The objective of the present study was to evaluate an in situ hardening biphasic (HA/β-TCP) bone graft substitutes for ridge preservation without primary wound closure or a dental membrane. METHODS: A total of 15 patients reported for tooth extraction were enrolled in this study. Implants were placed in average 5.2 ± 2 months after socket grafting...
December 2017: International Journal of Implant Dentistry
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