Wen-Der Lin, Chia-Hao Chang, Jhih-Kai Pan, Forn-Chia Lin, Yu-Chia Chen, Ya-Jyun Chen, Po-Shun Wang, Wei-Qiao Hong, Sheng-Yuan Chen, Cheng-Han Lin, Yao-Lung Kuo, Wei-Pang Chung, Hui-Chuan Cheng, Michael Hsiao, Chia-Ning Yang, Pei-Jung Lu
Breast cancer (BC) is the most common cancer and the leading cause of cancer-related deaths in women worldwide. The 5-year survival rate is over 90% in BC patients, but once BC cells metastasis into distal organs, it is dramatically decreasing to less than 30%. Especially, triple-negative breast cancer (TNBC) patients usually lead to poor prognosis and survival because of metastasis. Understanding the underline mechanisms of TNBC metastasis is a critical issue. Non-coding RNAs, including of lncRNAs and microRNAs, are non-protein-coding transcripts and have been reported as important regulators in TNBC metastasis...
May 2, 2024: Cell Death & Disease