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https://www.readbyqxmd.com/read/28422407/mutations-in-tgds-associated-with-additional-malformations-of-the-middle-fingers-and-halluces-atypical-catel-manzke-syndrome-in-a-fetus
#1
Katharina Schoner, Rainer Bald, Denise Horn, Helga Rehder, Uwe Kornak, Nadja Ehmke
Pierre-Robin sequence, radial deviation, and ulnar clinodactyly of the index fingers due to an additional phalangeal bone, as well as heart defects are the key features of Catel-Manzke syndrome. Although mutations in TGDS were identified as the cause of this disorder, the pathogenetic mechanism remains unknown. Here, we report on a fetus with severe heart defect, nuchal edema, talipes, Pierre-Robin sequence, and bilateral deviation and clinodactyly of the index and middle fingers. Pregnancy was terminated at the 22nd week of gestation...
April 19, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28410938/preservation-of-devitalized-bone-in-necrotic-digits-following-crush-injury-with-free-tissue-transfer
#2
Fei Song, Yongwei Pan, Zhe Zhao, Jiuzheng Deng, Changjiao Sun
Traditional management of necrotic digits has been to allow demarcation between viable and nonviable tissues to occur, and thus to indicate the level of amputation required. In this case report, the phalangeal length of the necrotic thumb was maintained in 2 patients who had sustained crush injury. After nonviable soft tissues were debrided, the devitalized bones were covered with soft tissue flaps. All wounds healed without infection. Both cosmetic and functional results of the reconstructed thumbs were satisfactory...
April 12, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28407064/the-influence-of-eye-closure-on-somatosensory-discrimination-a-trade-off-between-simple-perception-and-discrimination
#3
Theresa Götz, David Hanke, Ralph Huonker, Thomas Weiss, Carsten Klingner, Stefan Brodoehl, Philipp Baumbach, Otto W Witte
We often close our eyes to improve perception. Recent results have shown a decrease of perception thresholds accompanied by an increase in somatosensory activity after eye closure. However, does somatosensory spatial discrimination also benefit from eye closure? We previously showed that spatial discrimination is accompanied by a reduction of somatosensory activity. Using magnetoencephalography, we analyzed the magnitude of primary somatosensory (somatosensory P50m) and primary auditory activity (auditory P50m) during a one-back discrimination task in 21 healthy volunteers...
April 12, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28399657/cadaveric-evaluation-of-dorsal-intermetatarsal-approach-for-plantar-plate-and-lateral-collateral-ligament-repair-of-the-lesser-metatarsophalangeal-joints
#4
Phinit Phisitkul, Vinay Hosuru Siddappa, Tinnart Sittapairoj, Jessica E Goetz, Bryan D Den Hartog, John E Femino
BACKGROUND: Access to the plantar plate has been described using either a plantar approach or an extensive dorsal approach that required complete joint destabilization and often a metatarsal osteotomy. Clinical scenarios related to plantar plate tear vary and the pathologies in early stages are frequently limited to unilateral soft tissue structures; a less invasive operative approach may be possible. A novel approach requiring a release of only the lateral collateral ligament and the lateral half of the plantar plate is presented in this cadaver model; the extent of joint exposure possible is described...
April 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/28398696/accuracy-of-sonography-in-plantar-plate-tears-in-cadavers
#5
Michael Stone, William Eyler, Joshua Rhodenizer, Marnix van Holsbeeck
OBJECTIVES: Sonography is often used in the evaluation of forefoot disorders, and its use has been suggested in the diagnosis of plantar plate tears. This study aimed to assess the accuracy of sonography in the diagnosis of plantar plate tears of the lesser digits using gross dissection as the reference standard. METHODS: The second through fifth digits of 6 cadavers were examined with sonography to evaluate for plantar plate tears. The examination was performed by a single musculoskeletal radiologist in longitudinal and short axes, and plates were graded as torn or intact...
April 11, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28368070/-limb-fractures-in-32-small-ruminants-treatment-and-outcome
#6
Johann Kofler, Daniel Hochschwarzer, Kathrin Schieder, Adriana Osová, Britta Vidoni
OBJECTIVE: Retrospective evaluation of the records of 32 small ruminant patients that were treated for limb fractures between 2001 and 2014. MATERIALS AND METHODS: Records were analyzed regarding species, breed, and age of the animals, age, localization, and type of the fracture, the applied treatment method (conservative: using polyvinyl-chloride splints or casts; surgical: internal fixation techniques or limb amputation), and the final outcome. RESULTS: The 16 goats and 16 sheep (18 male, 14 female) had a mean age of 1...
April 3, 2017: Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere
https://www.readbyqxmd.com/read/28363042/clinical-management-of-third-phalanx-fractures-in-lesser-tragelaphus-imberbis-and-greater-kudu-tragelaphus-strepsiceros
#7
Anne E Rivas, Jennifer C Hausmann, John Gieche, Roberta Wallace, Cooper Williams, Ellen Bronson
Two greater kudu ( Tragelaphus strepsiceros ) and one lesser kudu ( T. imberbis ) from two zoological institutions presented with overgrown front hooves, and were diagnosed with fractures of the third phalanges in the affected digits. Both greater kudu had milder lamenesses at diagnosis, and were managed conservatively with hoof trims, stall rest, and nonsteroidal anti-inflammatory medications. Ongoing management through regular hoof trims led to improvement and eventual resolution of lameness. The more severely lame lesser kudu received hoof blocks on the front claws not associated with fractured phalanges...
March 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28338524/chronic-boutonniere-deformities-supple-or-stiff-a-new-surgical-technique-with-early-mobilization-in-11-cases
#8
Elodie Dubois, Frederic Teboul, Thomas Bihel, Jean-N Goubier
Injuries to the central slip of the extensor mechanism can lead to a Boutonniere deformity with important functional consequences. We report a series of 11 patients treated by lengthening-dorsalizing the lateral bands and tightening the central slip with early mobilization. The average age of the patients was 42 years (14;52). The extension defect of the proximal interphalangeal (PIP) joint was 64 degrees (80;55) and the hyperextension of the distal interphalangeal joint was 10 degrees (15;5). The surgery was performed with peripheral nerve block (sensitive), allowing dynamic adjustment of the tendinous sutures...
March 23, 2017: Techniques in Hand & Upper Extremity Surgery
https://www.readbyqxmd.com/read/28337536/functional-and-patient-reported-outcomes-of-the-swanson-metacarpo-phalangeal-arthroplasty-in-the-rheumatoid-hand
#9
Firas K Elherik, Sean Dolan, John Antrum, Frank Unglaub, Colin R Howie, Steffen J Breusch
INTRODUCTION: Replacement of the metacarpo-phalangeal joints (MCPJ) with silastic Swanson's implants can help decrease pain, stiffness and allow for improved function in rheumatoid arthritis (RA). There is a lack of patient reported outcome measure (PROM) studies assessing the efficacy of this procedure in RA. The aim of this study was to report any change in function, pain, stiffness and satisfaction following the Swanson MCPJ replacement using patient reported outcomes in a rheumatoid population...
May 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28332172/quantitative-ultrasound-and-dxa-measurements-in-aromatase-inhibitor-treated-breast-cancer-women-receiving-denosumab
#10
A Catalano, A Gaudio, N Morabito, G Basile, R M Agostino, A Xourafa, M Atteritano, E Morini, G Natale, A Lasco
PURPOSE: Denosumab has been proven to reduce fracture risk in breast cancer (BC) women under aromatase inhibitors (AIs). Quantitative ultrasound (QUS) provides information on the structure and elastic properties of bone. Our aim was to assess bone health by phalangeal QUS and by dual-energy X-ray absorptiometry (DXA), and to evaluate bone turnover in AIs-treated BC women receiving denosumab. METHODS: 35 Postmenopausal BC women on AIs were recruited (mean age 61...
March 22, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28316857/progressive-pseudorheumatoid-dysplasia-or-jia
#11
Geetha Wickrematilake
Progressive pseudorheumatoid dysplasia (PPD) or spondyloepiphyseal dysplasia tarda with progressive arthropathy (SEDT-PA) is a rare arthropathy of childhood involving the axial skeleton as well as small peripheral joints. A 10-year-old boy was referred by a general practitioner with pain and deformity in the fingers of hands and limping gait. There was no joint synovitis although the finger joints were bulky on examination with mild flexion deformity. Patient had exaggerated kyphosis and lumbar lordosis with pigeon chest and restricted hip joint movements...
2017: Case Reports in Rheumatology
https://www.readbyqxmd.com/read/28302355/effects-of-short-term-calcium-supplementation-in-children-and-adolescents-with-phenylketonuria
#12
Nancy Y Y Tanaka, Marlene F Turcato, Carolina F Nicoletti, Carla B Nonino, Luciana D Martins, Odilon Iannetta, Carlos Tostes Guerreiro, Gisele G Santos, Júlio S Marchini
Reduction of bone mineral density and the risk of osteopenia have been reported to occur in phenylketonuria (PKU) patients. This study aimed to evaluate the short-term effects of calcium supplementation in phenylketonuric children and adolescents. The study included 18 patients with PKU aged 5-18 yr (61% male) under clinical and nutritional treatment. Evaluation of food intake, anthropometry, and biochemical and phalangeal quantitative ultrasound were performed before (phase 1) and after (phase 2) calcium supplementation (1000 mg/d) for 34 d...
March 13, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28302234/tuberculous-dactylitis-with-concomitant-thyroid-involvement-a-rare-presentation-of-childhood-tuberculosis
#13
Sobia Qamar, Farrah Naz, Samia Naz, Iftikhar Ejaz
Extrapulmonary tuberculosis rarely presents as thyroid involvement along with other manifestations, and poses a diagnostic challenge on account of paucibacillary nature of disease. In general, the diagnosis of tuberculosis is based on epidemiological risk factors, clinical features, imaging studies, in addition to a positive skin testing or Interferon Gamma Release Assay (IGRA). A 14-year boy presented with history of fever and weight loss for one year. On examination, he had painful swelling of fingers and toes along with a painless thyroid nodule and squint...
March 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28293333/percutaneous-cannulated-compression-screw-osteosynthesis-in-phalanx-fractures-the-surgical-technique-the-indications-and-the-results
#14
Eirini Liodaki, Tobias Kisch, Eike Wenzel, Peter Mailänder, Felix Stang
Objective: Fractures of metacarpals and phalanges are very common fractures, and there are a lot of treatment modalities. The purpose of the study was to describe the technique of percutaneous fixation of phalangeal fractures using a cannulated compression screw fixation system and its results. Methods: We conducted a prospective clinical study on 43 patients with different types of phalangeal fractures undergoing a percutaneous cannulated compression screw osteosynthesis. Parameters such as average operation time and clinical outcome were evaluated postoperatively...
2017: Eplasty
https://www.readbyqxmd.com/read/28291522/fractures-and-dislocations-of-the-hand-in-polytrauma-patients-incidence-injury-pattern-and-functional-outcome
#15
Steven Ferree, Quirine M J van der Vliet, Mark van Heijl, Roderick M Houwert, Luke P H Leenen, Falco Hietbrink
INTRODUCTION: Injuries of the hand can cause significant functional impairment, diminished quality of life and delayed return to work. However, the incidence and functional outcome of hand injuries in polytrauma patients is currently unknown. The aim of this study was to determine the incidence, distribution and functional outcome of fractures and dislocation of the hand in polytrauma patients. METHODS: A single centre retrospective cohort study was performed at a level 1 trauma centre...
April 2017: Injury
https://www.readbyqxmd.com/read/28286765/digital-lengthening-to-treat-finger-deficiency-an-experience-of-201-digits-in-104-patients
#16
Zhenyu Ding, Xiaozhong Zhu, Kai Fu, Xianyou Zheng
Objectives. We evaluated the results of digital lengthening by distraction and second-stage bone graft. Methods. We treated finger deficiency of 201 digits in 104 patients (68 males, 36 females) by digital distraction and second-stage bone graft. The distraction was performed with a rate of 1 mm/day (for the first ten days) and 0.5 mm/day followed by using a self-designed bilateral tubal-helical external fixator. The mean follow-up period was 42 months (range 6 to 60 months). Results. The mean lengthening was 29...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28286623/effective-management-of-bone-fractures-with-the-illuminoss%C3%A2-photodynamic-bone-stabilization-system-initial-clinical-experience-from-the-european-union-registry
#17
Thomas Gausepohl, Dietmar Pennig, Steffen Heck, Sascha Gick, Paul A Vegt, Jon E Block
The IlluminOss(®) system (IS) uses a light-curable polymer contained within an inflatable balloon catheter, forming a patient customized intramedullary implant. A registry was established in Germany and The Netherlands to prospectively collect technical and clinical outcomes in patients treated with IS for fractures of the phalange, metacarpal, radius, ulna, distal radius, fibula, clavicle and/or olecranon. Humeral, femoral, tibial and pelvic fractures were included under compassionate use. Procedural success included successful placement of the device at the target fracture site and achievement of fracture stabilization...
February 20, 2017: Orthopedic Reviews
https://www.readbyqxmd.com/read/28280574/the-extreme-insular-adaptation-of-garganornis-ballmanni-meijer-2014-a-giant-anseriformes-of-the-neogene-of-the-mediterranean-basin
#18
Marco Pavia, Hanneke J M Meijer, Maria Adelaide Rossi, Ursula B Göhlich
New skeletal elements of the recently described endemic giant anseriform Garganornis ballmanni Meijer, 2014 are presented, coming from the type-area of the Gargano and from Scontrone, southern and central Italy, respectively. The new remains represent the first bird remains found at Scontrone so far, and another shared element between these two localities, both part of the Apulia-Abruzzi Palaeobioprovince. The presence of a very reduced carpometacarpus confirms its flightlessness, only previously supposed on the basis of the very large size, while the morphologies of tarsometatarsus and posterior phalanges clearly indicate the adaptation of G...
January 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28269397/hardness-map-of-human-meta-tarsals-and-phalanges-of-toes
#19
Irfan Manarvi
Predicting location of fracture in human bones has been a keen area of research for the past few decades. A variety of tests for hardness, deformation and strain field measurement have been conducted in the past; but considered insufficient due to various limitations. Researchers therefore have proposed further studies due to inaccuracies in measurement methods, testing machines and experimental errors. Advancement and availability of hardware, measuring instrumentation and testing machines can now provide remedies to these limitations...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269183/segmentation-of-the-metacarpus-and-phalange-in-musculoskeletal-ultrasound-images-using-local-active-contours
#20
Nelson Martins, Malik Saad Sultan, Diana Veiga, Manuel Ferreira, Miguel Coimbra
This work presents a method for the automatic segmentation of metacarpus and phalange bones in ultrasound images of the second metacarpophalangeal joint (MCPJ) using Active Contours. The MCPJ is known to be the one of the first structures to be affected by rheumatic diseases like rheumatoid arthritis. The early detection and follow-up of this disease is important to prevent irreversible damage of the joints, which occurs continuously and faster if no treatment is used. To our knowledge, there is no automatic system to quantify the extension of the lesions resulting from rheumatic activity...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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