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Barret oesophagus

Xavier Calvet
The most important novel findings presented on oesophageal disease in DDW 2015 were the following: 1) GERD: a) hypervigilance seems to be a key pathogenic factor in reflux symptoms refractory to PPI; b) post-reflux swallowing-induced peristaltic waves could be an excellent diagnostic criterion for GERD; c) laryngeal pH-metry is not useful in the diagnosis of extra-oesophageal symptoms; d) the recommendation of weight loss adequately recorded in the clinical reports of patients with GERD and obesity or overweight is an excellent quality indicator and is associated with better outcomes...
September 2015: Gastroenterología y Hepatología
Musa Özdogan, Hans Gottlieb
Hydropneumothorax following oesophageal rupture is very rare and often lethal. We report case of a 78-year-old man with known Barret's oesophagus with increasing shortness of breath and right chest pain followed by increasing emesis. Further investigations showed a right side hydropneumothorax and pleural effusion. Thorax and abdominal CT showed middle oesophageal perforation and pneumomediastinum. Oesophageal perforation can lead to pneumothorax and pleural fluid. Early diagnosis is pivotal to reduce mortality...
September 7, 2015: Ugeskrift for Laeger
E Dvir, R J Mellanby, M Kjelgaard-Hansen, J P Schoeman
The nematode Spirocerca lupi (S. lupi) induces sarcoma in the dog oesophagus in about 25% of cases. The aim of this study was to compare the differences in the cytokine milieu between dogs with neoplastic (n=29) and non-neoplastic disease (n=49) and age- and gender-matched healthy controls (n=25). We measured IL-2, IL-4, IL-6, IL-8, IL-10, IL-18, GM-CSF and MCP-1 in a specific canine multiplex immunoassay kit. Cytokine concentrations were compared between the different groups using the Kruskal-Wallis test followed by Dunn's test...
November 23, 2012: Veterinary Parasitology
Anouk van de Winkel, Katinka P M van Zoest, Herman van Dekken, Leon M G Moons, Ernst J Kuipers, Luc J W van der Laan
AIMS: To investigate expression of nuclear receptors farnesoid X receptor (FXR) and pregnane X receptor (PXR) as a diagnostic tool to improve grading of dysplasia in Barrett's oesophagus patients. METHODS AND RESULTS: Immunostaining was analysed on a total of 192 biopsy samples of 22 Barrett's patients with no dysplasia (ND), 17 with low-grade dysplasia (LGD), 20 high-grade dysplasia (HGD) and 24 with adenocarcinoma (AC). Nuclear FXR expression was observed in 15 of 22 (68%) ND cases versus none of 19 HGD; 3 of 17 (18%); LGD; 5 of 60 (8%) patients with AC (P<0...
January 2011: Histopathology
R Vrba, C Neoral, R Aujeský
This study assesses complications of a combined duodenogastric reflux disorder of the oesophagus. It has been proved that a degree of morphological affections of the mucosa is higher with an alcalic biliary reflux and can be assessed histologicaly. Primarily, the biliary portion of the reflux was assessed. Qualitative reflux parametres were assessed using a spectrophotometric examination. The examination can replace an expensive (and, therefore, generally unavailable) Bilitec 2000 system. In 21 subjects out of the total of 64 oesophageal reflux patients examined in the 2000-2003 period, complications of the disorder were confirmed...
January 2006: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
C Labouvie, J C Machado, F Carneiro, M Sarbia, M Vieth, R Porschen, G Seitz, N Blin
BACKGROUND AND AIMS: In humans, trefoil peptides (TFF peptides) and some mucins have been reported to be expressed in a cell-specific manner at mucosal surfaces of normal gastrointestinal tissues. Neoplastic conditions cause characteristic changes of these expression patterns. To study such patterns in Barrett's metaplasia and squamous cell carcinoma of the oesophagus (SCC), the distribution of MUC1, MUC2, MUC5AC and the three TFF peptides (TFF1, TFF2 and TFF3) was investigated. METHODS: In 40 archival samples of SCC and in 21 samples of Barret's metaplasia, expression of the three mucins and two TFF peptides (TFF1 and TFF2) was assessed by specific antibodies...
1999: Journal of Cancer Research and Clinical Oncology
L Fremond, O Bouché, M D Diébold, L Demange, P Zeitoun, G Thiefin
Barrett's oesophagus is a premalignant condition. The possibility of eradicating at least partially the metaplastic epithelium has been reported recently. In this case report, a patient with Barrett's oesophagus complicated by high grade dysplasia and focal adenocarcinoma was treated by Nd:Yag laser then high dose rate intraluminal irradiation while on omeprazole 40 mg/day. A partial eradication of Barrett's oesophagus and a transient tumoural regression were obtained. Histologically, residual specialized-type glandular tissue was observed beneath regenerative squamous epithelium...
January 1995: Gastroentérologie Clinique et Biologique
A Hawe, W S Payne, L H Weiland, R S Fontana
No abstract text is available yet for this article.
July 1973: Thorax
G A Martini, M Wienbeck
No abstract text is available yet for this article.
March 8, 1974: Deutsche Medizinische Wochenschrift
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