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Ko-Eun Choi, Bomi Park, Asma M Moheet, Amanda Rosen, Shouri Lahiri, Axel Rosengart
Shivering is a common side effect of targeted temperature modulation and general anesthesia. Antishivering strategies often employ a stepwise approach involving both pharmacological and physical interventions. However, approaches to treat shivering are often empiric and vary widely across care environments. We evaluated the quality of published antishivering protocols and guidelines with respect to methodological rigor, reliability, and consistency of recommendations. Using 4 medical databases, we identified 4027 publications that addressed shivering therapy, and excluded 3354 due to lack of relevance...
September 12, 2016: Anesthesia and Analgesia
E Ratemi, A Sultana Shaik, A Al Faraj, R Halwani
Despite the various treatment options and international guidelines currently available for the appropriate therapeutic management of asthma, a large population of patients with asthma continues to have poorly controlled disease. There is therefore a need for novel approaches to achieve better asthma control, especially for severe asthmatics. This review discusses the use of nanoparticles for the specific targeting of inflammatory pathways as a promising approach for the effective control of severe persistent asthma as well as other chronic inflammatory diseases...
August 2016: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
V Sanz de Burgoa, J Rejas, P Ojeda
BACKGROUND AND OBJECTIVE: Nocturnal asthma symptoms are associated with poor sleep quality, excessive daytime sleepiness, and poor daytime functioning. The aim of this study was to describe self-perceived sleep quality and quantity in asthmatic adults in a real-world setting according to different determinants of patient health status. METHODS: A cross-sectional, observational, seasonal, multiwave survey was designed. Allergists nationwide were asked to consecutively survey adult asthmatics aged 18 to 65 years, evenly distributed by seasons and asthma severity (Global Initiative for Asthma criteria)...
2016: Journal of Investigational Allergology & Clinical Immunology
Asma Khaliq, B Delia Johnson, R David Anderson, Anthony A Bavry, Rhonda M Cooper-DeHoff, Eileen M Handberg, C Noel Bairey Merz, Stephen J Nicholls, Steven Nissen, Carl J Pepine
OBJECTIVE: In women, metabolic syndrome (MetS) is associated with higher risk of ischemic heart disease-related adverse outcomes versus individual components. We examined the relationship of MetS to subclinical coronary atherosclerosis. METHODS: Women (n = 100) undergoing coronary angiography for suspected ischemia but without obstructive coronary artery disease (CAD) underwent intravascular ultrasound (IVUS) of a segment of the left coronary artery. A core lab, masked to other findings, assessed IVUS measures and normalized volume measures to pull-back length...
June 2015: Cardiovascular Endocrinology
Asma Rym Ben Romdhane, Wided Ben Ayoub, Emna Gouider
BACKGROUND: Despite legislative acts develloped, many deficiencies were identified in blood requests at the National Blood TransfusionCenter impedding board and blood safety. AIM: to evaluate the conformity of the different topics of packed red blood cells requests to the legislation. METHODS: Our study was prospective descriptive lasting six months (March-August 2011). It assessed all packed red blood cells requests which reached the national blood transfusion center...
June 2015: La Tunisie Médicale
Christopher T Lam, Marlee S Krieger, Jennifer E Gallagher, Betsy Asma, Lisa C Muasher, John W Schmitt, Nimmi Ramanujam
INTRODUCTION: Current guidelines by WHO for cervical cancer screening in low- and middle-income countries involves visual inspection with acetic acid (VIA) of the cervix, followed by treatment during the same visit or a subsequent visit with cryotherapy if a suspicious lesion is found. Implementation of these guidelines is hampered by a lack of: trained health workers, reliable technology, and access to screening facilities. A low cost ultra-portable Point of Care Tampon based digital colposcope (POCkeT Colposcope) for use at the community level setting, which has the unique form factor of a tampon, can be inserted into the vagina to capture images of the cervix, which are on par with that of a state of the art colposcope, at a fraction of the cost...
2015: PloS One
Rozina Hoque, Asma Mostafa, Mainul Haque
BACKGROUND: Bacterial resistance due to antibiotic misuse is reported every day. Such threat calls for a consensus to develop new strategies to prevent the development of antibiotic resistance of bacteria. Medical doctors must play a pivotal role to control and prevent the misuse of antibiotics. There were complaints that prescribers are lacking behind in updates and advancement in the field. To address such knowledge gap, a study was conducted to know the views of interns on the current antibiotic resistance situation in a teaching hospital in Bangladesh...
2015: Therapeutics and Clinical Risk Management
Kany Kany A Luabeya, Michele D Tameris, Hennie D Geldenhuys, Humphrey Mulenga, Amaryl Van Schalkwyk, Elizabeth J Hughes, Asma Toefey, Thomas J Scriba, Gregory Hussey, Hassan Mahomed, Helen McShane, Bernard Landry, Willem A Hanekom, Mark Hatherill
BACKGROUND: The risk of developing tuberculosis (TB) disease in HIV-uninfected children after isoniazid preventive therapy (IPT) for a positive QuantiFERON-TB Gold In-Tube test (QFT-GIT) is unknown. The aim of this study was to evaluate risk of TB disease after IPT in young HIV-uninfected children with a positive QFT-GIT result, or household TB contact. METHODS: HIV-uninfected South African infants aged 4-6 months were screened for enrolment in a TB vaccine trial...
November 2015: Pediatric Infectious Disease Journal
A Khalil, Asma Khalil, Argyro Syngelaki, Juliana Rezende, Kypros H Nicolaides
INTRODUCTION: Women who develop pregnancy complications are more likely to develop cardiovascular disorders later in life. A history of pre-eclampsia (PE) is associated with a four-fold increased risk of hypertension and twice the risk of future ischaemic heart disease and stroke. Early identification of women at risk of developing pregnancy complications is likely to facilitate targeted antenatal surveillance and possibly intervention. Maternal ethnicity affects the risk of developing some of these complications, and so is likely to be an important variable in the risk assessment...
July 2012: Pregnancy Hypertension
Claude Thibeault, Anthony D Evans
Medical Guidelines for Airline Travel provide information that enables healthcare providers to properly advise patients who plan to travel by air. Treating physicians should advise patients in need of special services to contact the airline well before travel to find out if the required services will be available. Ensuring the required services are available throughout a journey can be challenging, especially when different airlines and aircraft types are involved. For example, airlines carry a limited supply of oxygen for use in the event of an unexpected in-flight emergency; however, this supply is not intended for use by passengers needing supplemental oxygen...
July 2015: Aerospace Medicine and Human Performance
Claude Thibeault, Anthony D Evans, Nigel P Dowdall
Medical Guidelines for Airline Travel provide information that enables healthcare providers to properly advise patients who plan to travel by air. Not everyone is fit to travel by air and physicians should advise their patients accordingly. They should review the passenger's medical condition, giving special consideration to the dosage and timing of any medications, contagiousness, and the need for special assistance during travel. In general, an individual with an unstable medical condition should not fly; cabin altitude, duration of exposure, and altitude of the destination airport are all considerations when recommending a passenger for flight...
July 2015: Aerospace Medicine and Human Performance
Claude Thibeault, Anthony D Evans, Frank S Pettyjohn, Paulo M Alves
Medical Guidelines for Airline Travel provide information that enables healthcare providers to properly advise patients who plan to travel by air. All airlines are required to provide first aid training for cabin crew, and the crew are responsible for managing any in-flight medical events. There are also regulatory requirements for the carriage of first aid and medical kits. AsMA has developed recommendations for first aid kits, emergency medical kits, and universal precaution kits.
June 2015: Aerospace Medicine and Human Performance
Claude Thibeault, Anthony D Evans
Medical Guidelines for Airline Travel provide information that enables healthcare providers to properly advise patients who plan to travel by air. Although there are no publicly available databases providing information on the number of in-flight medical emergencies, the few studies published in the literature indicate that they are uncommon. Minor illnesses such as near-fainting, dizziness, and hyperventilation occur more frequently. However, serious illnesses, such as seizures and myocardial infarction, also occur...
June 2015: Aerospace Medicine and Human Performance
Claude Thibeault, Anthony D Evans
Medical Guidelines for Airline Travel provide information that enables healthcare providers to properly advise patients who plan to travel by air. Modern commercial aircraft are very safe and, in most cases, reasonably comfortable. However, all flights, short or long haul, impose stresses on passengers. Preflight stresses include airport commotion on the ground such as carrying baggage, walking long distances, getting to the gate on time, and being delayed. In-flight stresses include acceleration, vibration (including turbulence), noise, lowered barometric pressure, variations of temperature and humidity, and fatigue among others...
May 2015: Aerospace Medicine and Human Performance
Harrathi Ahlem, Halayem Soumeyya, Janhani Nadia, Othman Sami, Lahmar Ines, Blouza Samira, Belhadj Ahlem, Bouden Asma, Mohamed B Halayem
BACKGROUND: Anorexia nervosa is a complex psychiatric illness that can lead to severe physical complications. OBJECTIVE: This work aimed to study the approach taken by the child psychiatry service of Razi hospital in the management of anorexia nervosa and to compare it with international recommendation. METHODS: We propose to illustrate by a case report and review international recommendations on this topic while undertaking a review of the literature based on a Medline search using the following keywords: anorexia, nervosa adolescence, management, guidelines...
July 2014: La Tunisie Médicale
Richard L Haspel, Yulia Lin, Ranjeeta Mallick, Alan Tinmouth, Joan Cid, Hermann Eichler, Miguel Lozano, Leo van de Watering, Patrick B Fisher, Asma Ali, Eric Parks
BACKGROUND: Blood transfusion is the most common hospital procedure performed in the United States. While inadequate physician transfusion medicine knowledge may lead to inappropriate practice, such an educational deficit has not been investigated on an international scale using a validated assessment tool. Identifying specific deficiencies is critical for developing curricula to improve patient care. STUDY DESIGN AND METHODS: Rasch analysis, a method used in high-stakes testing, was used to validate an assessment tool consisting of a 23-question survey and a 20-question examination...
June 2015: Transfusion
Md Sarowar Jahan, Md Jahirul Islam, Rehana Begum, Ruhul Kayesh, Asma Rahman
A rapid and stability-indicating reversed phase high-performance liquid chromatography (RP-HPLC) method was developed for simultaneous quantification of paracetamol and ibuprofen in their combined dosage form especially to get some more advantages over other methods already developed for this combination. The method was validated according to United States Pharmacopeia (USP) guideline with respect to accuracy, precision, specificity, linearity, solution stability, robustness, sensitivity, and system suitability...
2014: Analytical Chemistry Insights
Khalid Ahmed Al-Anazi, Asma M Al-Jasser, Waleed Khalid Al-Anazi
Non-tuberculous mycobacteria (NTM) are acid-fast bacteria that are ubiquitous in the environment and can colonize soil, dust particles, water sources, and food supplies. They are divided into rapidly growing mycobacteria such as Mycobacterium fortuitum, Mycobacterium chelonae, and Mycobacterium abscessus as well as slowly growing species such as Mycobacterium avium, Mycobacterium kansasii, and Mycobacterium marinum. About 160 different species, which can cause community acquired and health care-associated infections, have been identified...
2014: Frontiers in Oncology
Mirjam C K Geditz, Georg Heinkele, Asma Ahmed, Peter G Kremsner, Reinhold Kerb, Matthias Schwab, Ute Hofmann
Artesunate (AS), a hemisuccinate derivative of artemisinin, is readily soluble in water and can easily be used in formulations for parenteral treatment of severe malaria. AS is rapidly hydrolyzed to the active metabolite dihydroartemisinin (DHA) and primarily eliminated by biliary excretion after glucuronidation. To investigate systematically the AS metabolism and pharmacokinetics, a novel liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the simultaneous quantification of AS and its metabolites DHA and DHA glucuronide (DHAG) in human plasma samples was developed...
July 2014: Analytical and Bioanalytical Chemistry
J Delgado, I D Dávila, J Domínguez-Ortega, S Quirce, E Martí-Guadaño, A Valero
OBJECTIVE: We aimed to analyze health-related quality of life (HRQOL) in adults with newly diagnosed respiratory allergy according to the sensitization profile for relevant aeroallergens in their usual area of residence. METHODS: We performed a cross-sectional, epidemiological, observational, descriptive, multicenter study in allergy clinics in Spain. The sample comprised adults diagnosed with rhinitis, asthma, or both caused by significant allergens in their residential area (olive and/or grass pollen or house dust mite)...
2013: Journal of Investigational Allergology & Clinical Immunology
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