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https://www.readbyqxmd.com/read/28188579/cardiac-biomarkers-of-acute-coronary-syndrome-from-history-to-high-sensitivity-cardiac-troponin
#1
REVIEW
Pankaj Garg, Paul Morris, Asma Lina Fazlanie, Sethumadhavan Vijayan, Balazs Dancso, Amardeep Ghosh Dastidar, Sven Plein, Christian Mueller, Philip Haaf
The role of cardiac troponins as diagnostic biomarkers of myocardial injury in the context of acute coronary syndrome (ACS) is well established. Since the initial 1st-generation assays, 5th-generation high-sensitivity cardiac troponin (hs-cTn) assays have been developed, and are now widely used. However, its clinical adoption preceded guidelines and even best practice evidence. This review summarizes the history of cardiac biomarkers with particular emphasis on hs-cTn. We aim to provide insights into using hs-cTn as a quantitative marker of cardiomyocyte injury to help in the differential diagnosis of coronary versus non-coronary cardiac diseases...
March 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28186368/gastrointestinal-involvement-in-the-ehlers-danlos-syndromes
#2
Asma Fikree, Gisela Chelimsky, Heidi Collins, Katcha Kovacic, Qasim Aziz
Current evidence suggests that an association exists between non-inflammatory hereditary disorders of connective tissue such as the Ehlers-Danlos syndromes (EDS) and gastrointestinal (GI) symptoms. Patients with EDS can present with both structural problems such as hiatus hernias, visceroptosis, rectoceles, and rectal prolapse as well as functional problems such as disordered gut motility. It has recently been demonstrated that patients with hypermobile EDS (hEDS) present with GI symptoms related to the fore and hind-gut and these patients frequently meet the criteria for functional gastrointestinal disorders such as functional dyspepsia and irritable bowel syndrome...
February 10, 2017: American Journal of Medical Genetics. Part C, Seminars in Medical Genetics
https://www.readbyqxmd.com/read/28174626/maternal-undernutrition-and-excessive-body-weight-and-risk-of-birth-and-health-outcomes
#3
Md Nuruzzaman Khan, Md Mizanur Rahman, Asma Ahmad Shariff, Md Mostafizur Rahman, Md Shafiur Rahman, Md Aminur Rahman
BACKGROUND: Overweight and obesity are increasing in low- and middle-income countries, while underweight remains a significant health problems. However, the association between double burden of nutrition and risk of adverse birth and health outcomes is still unclear in Bangladesh. The aim of this study was to determine the effect of maternal undernutrition and excessive body weight on a range of maternal and child health outcomes. METHODS: In this study, we used Bangladesh Demographic and Health Survey (BDHS) 2011 and 2014 data sets to cover the maternal, child and non-communicable diseases related health outcomes...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/28042368/neurological-prognostication-of-cardiac-arrest-in-an-era-of-extracorporeal-membrane-oxygenation
#4
Supreet K Sahai, Tamara Majic, Jignesh Patel, Michael Nurok, Asma M Moheet, Axel J Rosengart, Shouri Lahiri
A neuron-specific enolase level greater than 33 ng/mL at days 1 to 3 or status myoclonus within 1 day are traditional indicators of poor neurological prognosis in survivors of cardiac arrest. We report the case of a 70-year-old man who received extracorporeal membrane oxygenation following cardiac arrest. Despite having both an elevated neuron-specific enolase concentration of 68 ng/mL and status myoclonus, he made an excellent neurological recovery. The value of traditional markers of poor prognosis such as elevated neuron-specific enolase or status myoclonus has not been systematically validated in patients treated with extracorporeal membrane oxygenation or therapeutic hypothermia...
January 2017: Neurohospitalist
https://www.readbyqxmd.com/read/27986740/self-reported-breast-feeding-practices-and-the-baby-friendly-hospital-initiative-in-riyadh-saudi-arabia-prospective-cohort-study
#5
Cynthia Mosher, Abdullah Sarkar, Alaa AbouBakr Hashem, Reem E Hamadah, Asma Alhoulan, Yosra A AlMakadma, Tehreem A Khan, Abdurahman K Al-Hamdani, Abiola Senok
BACKGROUND: The Baby Friendly Hospital Initiative (BFHI) is a practice guideline for healthcare providers to promote breastfeeding and increase breastfeeding rates. OBJECTIVE: This study aimed to examine reported experiences and views on breastfeeding of women using prenatal and postnatal services, and opinions of staff, in the context of the BFHI programme in Riyadh, Saudi Arabia. DESIGN: Prospective cohort study. SETTING: This prospective, longitudinal study was conducted from December 2013 to September 2015 at two healthcare facilities (BFHI and non-BFHI) in Riyadh Saudi Arabia...
December 16, 2016: BMJ Open
https://www.readbyqxmd.com/read/27942364/a-low-prevalence-of-inducible-macrolide-lincosamide-and-streptogramin-b-resistance-phenotype-among-methicillin-susceptible-staphylococcus-aureus-isolated-from-malaysian-patients-and-healthy-individuals
#6
Asma Mesbah Elkammoshi, Hamed Ghasemzadeh-Moghaddam, Syafinaz Amin Nordin, Niazlin Mohd Taib, Suresh Kumar Subbiah, Vasanthakumari Neela, Rukman Awang Hamat
BACKGROUND: Antibiotic resistance among Staphylococcus aureus is of great concern worldwide. This resistance is further complicated by the ability of S. aureus to confer cross-resistance to other antibiotics due to the presence of resistance genes, such as erythromycin resistance methylase (erm) genes, which render the bacterium resistant to macrolide-lincosamide-streptogramin B (MLSB) antibiotics. Resistance to these antibiotics can lead to therapeutic failure, resulting in significant morbidity and mortality in patients with S...
October 2016: Jundishapur Journal of Microbiology
https://www.readbyqxmd.com/read/27622717/systematic-quality-assessment-of-published-antishivering-protocols
#7
Ko-Eun Choi, Bomi Park, Asma M Moheet, Amanda Rosen, Shouri Lahiri, Axel Rosengart
Shivering is a common side effect of targeted temperature modulation and general anesthesia. Antishivering strategies often employ a stepwise approach involving both pharmacological and physical interventions. However, approaches to treat shivering are often empiric and vary widely across care environments. We evaluated the quality of published antishivering protocols and guidelines with respect to methodological rigor, reliability, and consistency of recommendations.Using 4 medical databases, we identified 4027 publications that addressed shivering therapy, and excluded 3354 due to lack of relevance...
May 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27404025/alternative-approaches-for-the-treatment-of-airway-diseases-focus-on-nanoparticle-medicine
#8
REVIEW
E Ratemi, A Sultana Shaik, A Al Faraj, R Halwani
Despite the various treatment options and international guidelines currently available for the appropriate therapeutic management of asthma, a large population of patients with asthma continues to have poorly controlled disease. There is therefore a need for novel approaches to achieve better asthma control, especially for severe asthmatics. This review discusses the use of nanoparticles for the specific targeting of inflammatory pathways as a promising approach for the effective control of severe persistent asthma as well as other chronic inflammatory diseases...
August 2016: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27373924/self-perceived-sleep-quality-and-quantity-in-adults-with-asthma-findings-from-the-costeasma-study
#9
V Sanz de Burgoa, J Rejas, P Ojeda
BACKGROUND AND OBJECTIVE: Nocturnal asthma symptoms are associated with poor sleep quality, excessive daytime sleepiness, and poor daytime functioning. The aim of this study was to describe self-perceived sleep quality and quantity in asthmatic adults in a real-world setting according to different determinants of patient health status. METHODS: A cross-sectional, observational, seasonal, multiwave survey was designed. Allergists nationwide were asked to consecutively survey adult asthmatics aged 18 to 65 years, evenly distributed by seasons and asthma severity (Global Initiative for Asthma criteria)...
2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/26665010/relationships-between-components-of-metabolic-syndrome-and-coronary-intravascular-ultrasound-atherosclerosis-measures-in-women-without-obstructive-coronary-artery-disease-the-nhlbi-sponsored-women-s-ischemia-syndrome-evaluation-study
#10
Asma Khaliq, B Delia Johnson, R David Anderson, Anthony A Bavry, Rhonda M Cooper-DeHoff, Eileen M Handberg, C Noel Bairey Merz, Stephen J Nicholls, Steven Nissen, Carl J Pepine
OBJECTIVE: In women, metabolic syndrome (MetS) is associated with higher risk of ischemic heart disease-related adverse outcomes versus individual components. We examined the relationship of MetS to subclinical coronary atherosclerosis. METHODS: Women (n = 100) undergoing coronary angiography for suspected ischemia but without obstructive coronary artery disease (CAD) underwent intravascular ultrasound (IVUS) of a segment of the left coronary artery. A core lab, masked to other findings, assessed IVUS measures and normalized volume measures to pull-back length...
June 2015: Cardiovascular Endocrinology
https://www.readbyqxmd.com/read/26644098/-evaluation-of-non-compliance-of-transfusion-requests-of-packed-red-blood-cells
#11
MULTICENTER STUDY
Asma Rym Ben Romdhane, Wided Ben Ayoub, Emna Gouider
BACKGROUND: Despite legislative acts develloped, many deficiencies were identified in blood requests at the National Blood TransfusionCenter impedding board and blood safety. AIM: to evaluate the conformity of the different topics of packed red blood cells requests to the legislation. METHODS: Our study was prospective descriptive lasting six months (March-August 2011). It assessed all packed red blood cells requests which reached the national blood transfusion center...
June 2015: La Tunisie Médicale
https://www.readbyqxmd.com/read/26332673/design-of-a-novel-low-cost-point-of-care-tampon-pocket-colposcope-for-use-in-resource-limited-settings
#12
Christopher T Lam, Marlee S Krieger, Jennifer E Gallagher, Betsy Asma, Lisa C Muasher, John W Schmitt, Nimmi Ramanujam
INTRODUCTION: Current guidelines by WHO for cervical cancer screening in low- and middle-income countries involves visual inspection with acetic acid (VIA) of the cervix, followed by treatment during the same visit or a subsequent visit with cryotherapy if a suspicious lesion is found. Implementation of these guidelines is hampered by a lack of: trained health workers, reliable technology, and access to screening facilities. A low cost ultra-portable Point of Care Tampon based digital colposcope (POCkeT Colposcope) for use at the community level setting, which has the unique form factor of a tampon, can be inserted into the vagina to capture images of the cervix, which are on par with that of a state of the art colposcope, at a fraction of the cost...
2015: PloS One
https://www.readbyqxmd.com/read/26316762/intern-doctors-views-on-the-current-and-future-antibiotic-resistance-situation-of-chattagram-maa-o-shishu-hospital-medical-college-bangladesh
#13
Rozina Hoque, Asma Mostafa, Mainul Haque
BACKGROUND: Bacterial resistance due to antibiotic misuse is reported every day. Such threat calls for a consensus to develop new strategies to prevent the development of antibiotic resistance of bacteria. Medical doctors must play a pivotal role to control and prevent the misuse of antibiotics. There were complaints that prescribers are lacking behind in updates and advancement in the field. To address such knowledge gap, a study was conducted to know the views of interns on the current antibiotic resistance situation in a teaching hospital in Bangladesh...
2015: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/26252568/risk-of-disease-after-isoniazid-preventive-therapy-for-mycobacterium-tuberculosis-exposure-in-young-hiv-uninfected-children
#14
Kany Kany A Luabeya, Michele D Tameris, Hennie D Geldenhuys, Humphrey Mulenga, Amaryl Van Schalkwyk, Elizabeth J Hughes, Asma Toefey, Thomas J Scriba, Gregory Hussey, Hassan Mahomed, Helen McShane, Bernard Landry, Willem A Hanekom, Mark Hatherill
BACKGROUND: The risk of developing tuberculosis (TB) disease in HIV-uninfected children after isoniazid preventive therapy (IPT) for a positive QuantiFERON-TB Gold In-Tube test (QFT-GIT) is unknown. The aim of this study was to evaluate risk of TB disease after IPT in young HIV-uninfected children with a positive QFT-GIT result, or household TB contact. METHODS: HIV-uninfected South African infants aged 4-6 months were screened for enrolment in a TB vaccine trial...
November 2015: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/26105241/os027-ethnicity-and-adverse-pregnancy-outcomes-a-cohort-study
#15
A Khalil, Asma Khalil, Argyro Syngelaki, Juliana Rezende, Kypros H Nicolaides
INTRODUCTION: Women who develop pregnancy complications are more likely to develop cardiovascular disorders later in life. A history of pre-eclampsia (PE) is associated with a four-fold increased risk of hypertension and twice the risk of future ischaemic heart disease and stroke. Early identification of women at risk of developing pregnancy complications is likely to facilitate targeted antenatal surveillance and possibly intervention. Maternal ethnicity affects the risk of developing some of these complications, and so is likely to be an important variable in the risk assessment...
July 2012: Pregnancy Hypertension
https://www.readbyqxmd.com/read/26102149/asma-medical-guidelines-for-air-travel-airline-special-services
#16
Claude Thibeault, Anthony D Evans
Medical Guidelines for Airline Travel provide information that enables healthcare providers to properly advise patients who plan to travel by air. Treating physicians should advise patients in need of special services to contact the airline well before travel to find out if the required services will be available. Ensuring the required services are available throughout a journey can be challenging, especially when different airlines and aircraft types are involved. For example, airlines carry a limited supply of oxygen for use in the event of an unexpected in-flight emergency; however, this supply is not intended for use by passengers needing supplemental oxygen...
July 2015: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/26102148/asma-medical-guidelines-for-air-travel-fitness-to-fly-and-medical-clearances
#17
Claude Thibeault, Anthony D Evans, Nigel P Dowdall
Medical Guidelines for Airline Travel provide information that enables healthcare providers to properly advise patients who plan to travel by air. Not everyone is fit to travel by air and physicians should advise their patients accordingly. They should review the passenger's medical condition, giving special consideration to the dosage and timing of any medications, contagiousness, and the need for special assistance during travel. In general, an individual with an unstable medical condition should not fly; cabin altitude, duration of exposure, and altitude of the destination airport are all considerations when recommending a passenger for flight...
July 2015: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/26099132/asma-medical-guidelines-for-air-travel-in-flight-medical-care
#18
Claude Thibeault, Anthony D Evans, Frank S Pettyjohn, Paulo M Alves
Medical Guidelines for Airline Travel provide information that enables healthcare providers to properly advise patients who plan to travel by air. All airlines are required to provide first aid training for cabin crew, and the crew are responsible for managing any in-flight medical events. There are also regulatory requirements for the carriage of first aid and medical kits. AsMA has developed recommendations for first aid kits, emergency medical kits, and universal precaution kits.
June 2015: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/26099131/asma-medical-guidelines-for-air-travel-reported-in-flight-medical-events-and-death
#19
Claude Thibeault, Anthony D Evans
Medical Guidelines for Airline Travel provide information that enables healthcare providers to properly advise patients who plan to travel by air. Although there are no publicly available databases providing information on the number of in-flight medical emergencies, the few studies published in the literature indicate that they are uncommon. Minor illnesses such as near-fainting, dizziness, and hyperventilation occur more frequently. However, serious illnesses, such as seizures and myocardial infarction, also occur...
June 2015: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/25945668/asma-medical-guidelines-for-air-travel-stresses-of-flight
#20
Claude Thibeault, Anthony D Evans
Medical Guidelines for Airline Travel provide information that enables healthcare providers to properly advise patients who plan to travel by air. Modern commercial aircraft are very safe and, in most cases, reasonably comfortable. However, all flights, short or long haul, impose stresses on passengers. Preflight stresses include airport commotion on the ground such as carrying baggage, walking long distances, getting to the gate on time, and being delayed. In-flight stresses include acceleration, vibration (including turbulence), noise, lowered barometric pressure, variations of temperature and humidity, and fatigue among others...
May 2015: Aerospace Medicine and Human Performance
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