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https://www.readbyqxmd.com/read/28808375/chemopreventive-and-antioxidant-effect-of-polyphenol-free-spirulina-maxima-and-its-hydrolyzed-protein-content-investigation-on-azoxymethane-treated-mice
#1
Nikte Y Martínez-Palma, Gloria Dávila-Ortiz, Cristian Jiménez-Martínez, Eduardo Madrigal-Bujaidar, Isela Álvarez-González
BACKGROUND: Spirulina maxima (Sm) is known to have nutritive value as well as a number of potentially useful biomedical properties. OBJECTIVES: The initial purpose of this report was to evaluate the inhibitory effect of the alga (without its polyphenol content), on the induction of azoxymethane (AOM)-induced colon aberrant crypts (AC) in mouse. Besides, we hydrolyzed the protein content of such mixture. Our second aim was to determine the inhibitory potential of this last plant mixture on the AOM-induced colon AC in mouse...
July 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28801770/nutrient-composition-of-culture-media-induces-different-patterns-of-co2-fixation-from-biogas-and-biomass-production-by-the-microalga-scenedesmus-obliquus-u169
#2
Francisco J Choix, Elena Polster, Rosa Isela Corona-González, Raúl Snell-Castro, Hugo O Méndez-Acosta
Microalgae are considered as a promising biotechnological strategy to capture CO2 from biogas, producing biomass with valuable energetic compounds. This study has evaluated the biotechnological potential to fix CO2 from biogas and biomass production by Scenedesmus obliquus cultured in four different formulations of culture media, C30, Bristol, Bold 3N, and C30+M, as well as the effect of methane (CH4) of biogas during CO2 fixation and biomass production. The results obtained showed that different nutrient composition and concentration of culture media, mainly micronutrient and vitamin concentrations, induced different patterns of CO2 fixation from biogas and biomass production in S...
August 11, 2017: Bioprocess and Biosystems Engineering
https://www.readbyqxmd.com/read/28772337/microalgae-community-shifts-during-the-biogas-upgrading-in-an-alkaline-open-photobioreactor
#3
Claudia Isela Granada-Moreno, Arturo Aburto-Medina, Daniel de Los Cobos Vasconcelos, Armando González-Sánchez
AIMS: To achieve the functional specialization of a microalgae community through operational tuning of an open-photobioreactor used for biogas upgrading under alkaline conditions. METHODS AND RESULTS: An open-photobioreactor was inoculated with an indigenous microalgae sample from the Texcoco Soda-Lake. A microalgae community was adapted to fix CO2 from synthetic biogas through different culture conditions reaching a maximum of 220 mg CO2 L(-1) d(-1) . Picochlorum sp...
August 3, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28756290/exploring-the-association-between-bdnf-val66met-polymorphism-and-suicidal-behavior-meta-analysis-and-systematic-review
#4
Thelma Beatriz González-Castro, Marisol Salas-Magaña, Isela Esther Juárez-Rojop, María Lilia López-Narváez, Carlos Alfonso Tovilla-Zárate, Yazmín Hernández-Díaz
Suicide is a serious worldwide health problem of critical consequences. Nowadays genetic factors are considered to be an important cause of suicide. The association between Val66Met (rs6265) polymorphism of the BDNF gene and suicide behavior has been increasingly studied. The aim of this study was to perform a meta-analysis in order to unravel the possible association between BDNF gene Val66Met polymorphism and suicide behavior. These meta-analysis and systematic review were performed using 23 articles that searched for a genetic association between Val66Met and suicide behavior, including 4532 cases and 5364 control subjects...
July 22, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28751391/complete-genome-sequences-of-eight-rhizobium-symbionts-associated-with-common-bean-phaseolus-vulgaris
#5
Rosa Isela Santamaría, Patricia Bustos, Olga María Pérez-Carrascal, Fabiola Miranda-Sánchez, Pablo Vinuesa, Irma Martínez-Flores, Soledad Juárez, Luis Lozano, Esperanza Martínez-Romero, Miguel Ángel Cevallos, David Romero, Guillermo Dávila, Ernesto Ormeño-Orrillo, Víctor González
We present here the high-quality complete genome sequences of eight strains of Rhizobium-nodulating Phaseolus vulgaris Comparative analyses showed that some of them belonged to different genomic and evolutionary lineages with common symbiotic properties. Two novel symbiotic plasmids (pSyms) with P. vulgaris specificity are reported here.
July 27, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28749738/nutraceutical-potential-of-new-alfalfa-medicago-sativa-ingredients-for-beverage-preparations
#6
Maria Guadalupe Soto-Zarazúa, Moustapha Bah, Anabela Silvia Gomes Costa, Francisca Rodrigues, Filipa Botelho Pimentel, Isela Rojas-Molina, Alejandra Rojas, Maria Beatriz Prior Pinto Oliveira
Alfalfa (Medicago sativa) has been extensively used as animal feed, due to its fiber, protein, minerals, and vitamins, being also a useful source of phenolic compounds with potential therapeutic benefits. Nevertheless, its potential use as human ingredient is scarce. The aim of this work was to assess the nutritional composition, amino acid profile, and antioxidant capacity (AOC) of freeze-dried juice (FDJ) and fibrous residual material (RM), two new alfalfa-derived products (Adps) recently launched as ingredients for beverage preparations...
July 27, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28734803/distribution-of-kir-genes-and-kir2ds4-gene-variants-in-two-mexican-mestizo-populations
#7
Machado-Sulbaran Andrea Carolina, Muñoz-Valle José Francisco, Ramírez-Dueñas María Guadalupe, Baños-Hernández Christian Johana, Machuca-Graciano Omar, Velarde-De la Cruz Erandi Enif, Parra-Rojas Isela, Sánchez-Hernández Pedro Ernesto
Killer immunoglobulin-like receptors (KIR) are transmembrane proteins that regulate NK and T cell subsets by recognizing HLA-I molecules as ligands. The KIR gene family consists of 16 genes, located at chromosome 19q13.4. KIR gene frequencies vary among populations. In Mexico, HLA and genetic ancestry studies show that Mestizo populations have different genetic backgrounds based on admixture with European, African, and Asian ancestry. This study aimed to evaluate the frequencies of KIR genes and genotypes in Guerrero and Jalisco, two Mexican Mestizo populations located in the south and the west of the country, respectively, and to compare these frequencies with those of other populations...
July 19, 2017: Human Immunology
https://www.readbyqxmd.com/read/28691514/effect-of-heat-treatment-to-sweet-potato-flour-on-dough-properties-and-characteristics-of-sweet-potato-wheat-bread
#8
Isela Carballo Pérez, Tai-Hua Mu, Miao Zhang, Lei-Lei Ji
The effect of heat treatment at 90, 100, 110 and 120 ℃ for 20 min to sweet potato flour on dough properties and characteristics of sweet potato-wheat bread was investigated. The lightness (L*) and a* of sweet potato flour samples after heat treatment were increased, while the b* were decreased significantly, as well as the particle size, volume and area mean diameter ( p < 0.05). A slight change of the microstructures of sweet potato flour was observed, where the number of irregular granules increased as the temperature increased from 90 to 120 ℃...
January 1, 2017: Food Science and Technology International, Ciencia y Tecnología de Los Alimentos Internacional
https://www.readbyqxmd.com/read/28677623/acute-consumption-of-resistant-starch-reduces-food-intake-but-has-no-effect-on-appetite-ratings-in-healthy-subjects
#9
Jorge L Ble-Castillo, Isela E Juárez-Rojop, Carlos A Tovilla-Zárate, Carlos García-Vázquez, Magda Z Servin-Cruz, Arturo Rodríguez-Hernández, Claudia I Araiza-Saldaña, Ana M Nolasco-Coleman, Juan C Díaz-Zagoya
Previous studies have shown the benefits of native banana starch (NBS) supplementation in improving glucose metabolism and reducing body weight (BW) in humans. However, the effect of this starch on appetite regulation is unknown. The aim of this study was to examine the effects of NBS rich resistant starch on subjective measurements of appetite, energy intake, and appetite hormones in healthy subjects. Postprandial glucose and insulin responses were also assessed. In a randomized, single-blind, crossover study, 28 healthy young subjects consumed a beverage containing either 40 g of NBS or 40 g of digestible corn starch (DCS) on two separate occasions...
July 4, 2017: Nutrients
https://www.readbyqxmd.com/read/28671531/genomic-and-physiological-characterization-of-a-laboratory-isolated-acinetobacter-schindleri-ace-strain-that-quickly-and-efficiently-catabolizes-acetate
#10
Juan-Carlos Sigala, Brisa Paola Suárez, Alvaro R Lara, Sylvie Le Borgne, Patricia Bustos, Rosa Isela Santamaría, Víctor González, Alfredo Martinez
An Acinetobacter strain, designated ACE, was isolated in the laboratory. Phylogenetic tests and average nucleotide identity value comparisons suggested that ACE belongs to the species Acinetobacterschindleri. We report for the first time the complete genome sequence of an A. schindleri strain, which consists of a single circular chromosome of 3 001 209 bp with an overall DNA G+C content of 42.9 mol% and six plasmids that account for 266 844 bp of extrachromosomal material. The presence or absence of genes related to carbon catabolism and antibiotic resistance were in agreement with the phenotypic characterization of ACE...
July 3, 2017: Microbiology
https://www.readbyqxmd.com/read/28657468/cooked-chickpea-consumption-inhibits-colon-carcinogenesis-in-mice-induced-with-azoxymethane-and-dextran-sulfate-sodium
#11
Xariss M Sánchez Chino, Cristian Jiménez Martínez, Verónica R Vásquez Garzón, Isela Álvarez González, Saúl Villa Treviño, Eduardo Madrigal Bujaidar, Gloria Dávila Ortiz, Rafael Baltiérrez Hoyos
SCOPE: The objective of the study was to evaluate the effect of daily consumption of cooked chickpea (2% and 10%) in ICR male mice in which colon cancer was induced with azoxymethane and dextran sulfate sodium. METHODS AND RESULTS: The effect of consumption of 2% or 10% cooked chickpeas on carcinogenesis-induced colon azoxymethane (AOM)/dextran sulfate sodium (DSS) in ICR mice was determined. Protein oxidation and lipids were determined by colorimetric methods and oxidation of DNA through the identification of adducts 8-hydroxy-2'-desoxiguanosine and proliferation markers (proliferating cell nuclear antigen [PCNA], Ki-67, and β-catenin), and inflammation (cyclooxygenase [COX]-2 and inducible nitric oxide synthase [iNOS]) were identified by immunohistochemistry reactions...
July 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28638711/decrease-in-brain-derived-neurotrophic-factor-at-plasma-level-but-not-in-serum-concentrations-in-suicide-behavior-a%C3%A2-systematic-review-and-meta-analysis
#12
Marisol Salas-Magaña, Carlos A Tovilla-Zárate, Thelma B González-Castro, Isela E Juárez-Rojop, María L López-Narváez, José M Rodríguez-Pérez, Julián Ramírez Bello
INTRODUCTION: Suicide is known as a major health concern worldwide. There is evidence for the role of brain-derived neurotrophic factor (BDNF) in suicide behavior. Therefore, this factor has been proposed as a biomarker for suicide behavior. Clinical studies have measured BDNF concentrations at central and peripheral levels. As a consequence, the aim of this study was to assess BDNF levels in blood plasma and serum to see whether there is a difference in concentrations in patients with suicide behavior when compared to those in controls, using a meta-analysis approach...
June 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28564690/volume-holographic-imaging-endoscopic-design-and-construction-techniques
#13
Isela D Howlett, Wanglei Han, Michael Gordon, Photini Rice, Jennifer K Barton, Raymond K Kostuk
No abstract text is available yet for this article.
May 1, 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/28551357/padi4-polymorphisms-and-the-functional-haplotype-are-associated-with-increased-rheumatoid-arthritis-susceptibility-a-replication-study-in-a-southern-mexican-population
#14
Christian Johana Baños-Hernández, José Eduardo Navarro-Zarza, Isela Parra-Rojas, Mirna Vázquez-Villamar, Jorge Ramón Padilla-Gutiérrez, Yeminia Valle, Zyanya Reyes-Castillo, Nora Magdalena Torres-Carrillo, Samuel García-Arellano, Lorena Michele Brennan-Bourdon, José Francisco Muñoz-Valle
Rheumatoid arthritis (RA) is a common autoimmune disease with a complex genetic background. The peptidyl arginine deiminase type IV (PADI4) gene has been associated with RA susceptibility in several populations. We addressed the relationship between three exonic PADI4 gene single nucleotide polymorphisms (SNPs) PADI4_89 (rs11203366), PADI4_90 (rs11203367) and PADI4_92 (rs874881) and related haplotypes with RA in a population from Southern México. This study included 200 RA patients and 200 control subjects...
May 25, 2017: Human Immunology
https://www.readbyqxmd.com/read/28515782/ecotypic-differentiation-under-farmers-selection-molecular-insights-into-the-domestication-of-pachyrhizus-rich-ex-dc-fabaceae-in-the-peruvian-andes
#15
Marc Delêtre, Beatriz Soengas, Prem Jai Vidaurre, Rosa Isela Meneses, Octavio Delgado Vásquez, Isabel Oré Balbín, Monica Santayana, Bettina Heider, Marten Sørensen
Understanding the distribution of crop genetic diversity in relation to environmental factors can give insights into the eco-evolutionary processes involved in plant domestication. Yam beans (Pachyrhizus Rich. ex DC.) are leguminous crops native to South and Central America that are grown for their tuberous roots but are seed-propagated. Using a landscape genetic approach, we examined correlations between environmental factors and phylogeographic patterns of genetic diversity in Pachyrhizus landrace populations...
June 2017: Evolutionary Applications
https://www.readbyqxmd.com/read/28512247/targetable-t-type-calcium-channels-drive-glioblastoma
#16
Ying Zhang, Nichola Cruickshanks, Fang Yuan, Baomin Wang, Mary Pahuski, Julia Wulfkuhle, Isela Gallagher, Alexander F Koeppel, Sarah Hatef, Christopher Papanicolas, Jeongwu Lee, Eli E Bar, David Schiff, Stephen D Turner, Emanuel F Petricoin, Lloyd S Gray, Roger Abounader
Glioblastoma (GBM) stem-like cells (GSC) promote tumor initiation, progression, and therapeutic resistance. Here, we show how GSCs can be targeted by the FDA-approved drug mibefradil, which inhibits the T-type calcium channel Cav3.2. This calcium channel was highly expressed in human GBM specimens and enriched in GSCs. Analyses of the The Cancer Genome Atlas and REMBRANDT databases confirmed upregulation of Cav3.2 in a subset of tumors and showed that overexpression associated with worse prognosis. Mibefradil treatment or RNAi-mediated attenuation of Cav3...
July 1, 2017: Cancer Research
https://www.readbyqxmd.com/read/28501219/headspace-single-drop-microextraction-coupled-with-microvolume-fluorospectrometry-for-highly-sensitive-determination-of-bromide
#17
Adrián García-Figueroa, Francisco Pena-Pereira, Isela Lavilla, Carlos Bendicho
This work reports on the development of a novel methodology for bromide determination by combining headspace single-drop microextraction with microvolume fluorospectrometry. The method lies in the in situ generation of bromine, transfer of the volatile to the headspace and trapping/reaction onto a fluorescein-containing aqueous drop exposed to the gas phase. The decrease in the fluorescence intensity enabled the determination of bromide without dilution of the enriched microdrop. Experimental parameters influencing the performance of the method, namely, fluorescence parameters, extractant phase composition, bromine generation conditions and microextraction time, were evaluated and controlled...
August 1, 2017: Talanta
https://www.readbyqxmd.com/read/28480389/evaluation-of-the-anti-inflammatory-capacity-of-beta-sitosterol-in-rodent-assays
#18
Rogelio Paniagua-Pérez, Gabriela Flores-Mondragón, Celia Reyes-Legorreta, Brígida Herrera-López, Isabel Cervantes-Hernández, Osiris Madrigal-Santillán, José Antonio Morales-González, Isela Álvarez-González, Eduardo Madrigal-Bujaidar
BACKGROUND: Beta-sitosterol (BS) is a compound discovered to be present in numerous plants. A number of interesting biomedical properties have been attributed to BS, including immuno-modulating and anti-inflammatory activities. Therefore, the aim of this report was to evaluate its anti-inflammatory capacity by applying various rodent experimental tests. METHODS: To carry out the objective of the study we applied the methods indicated here. Two of the adopted methods were based on the passive reverse Arthus reaction: the rat paw edema test and the rat pleurisy assay...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28468774/synergy-between-androgen-receptor-antagonism-and-inhibition-of-mtor-and-her2-in-breast-cancer
#19
Michael A Gordon, Nicholas C D'Amato, Haihua Gu, Beatrice Babbs, Julia Wulfkuhle, Emanuel F Petricoin, Isela Gallagher, Ting Dong, Kathleen Torkko, Bolin Liu, Anthony Elias, Jennifer K Richer
The androgen receptor (AR) is widely expressed in breast cancer, and evidence suggests dependence on AR signaling for growth and survival. AR antagonists such as enzalutamide and seviteronel have shown success in preclinical models and clinical trials of prostate cancer and are currently being evaluated in breast cancer. Reciprocal regulation between AR and the HER2/PI3K/mTOR pathway may contribute to resistance to HER2- and mTOR-targeted therapies; thus, dual inhibition of these pathways may synergistically inhibit breast cancer growth...
July 2017: Molecular Cancer Therapeutics
https://www.readbyqxmd.com/read/28446508/enrichment-of-pi3k-akt-mtor-pathway-activation-in-hepatic-metastases-from-breast-cancer
#20
Mariaelena Pierobon, Corinne Ramos, Shukmei Wong, K Alex Hodge, Jessica Aldrich, Sara Byron, Stephen P Anthony, Nicholas J Robert, Donald W Northfelt, Mohammad Jahanzeb, Linda Vocila, Julia Wulfkuhle, Guido Gambara, Rosa I Gallagher, Bryant Dunetz, Nicholas Hoke, Ting Dong, David W Craig, Massimo Cristofanilli, Brian Leyland-Jones, Lance A Liotta, Joyce A O'Shaughnessy, John D Carpten, Emanuel F Petricoin
Purpose: Little is known about the molecular signatures associated with specific metastatic sites in breast cancer. Using comprehensive multi-omic molecular profiling, we assessed whether alterations or activation of the PI3K-AKT-mTOR pathway is associated with specific sites of breast cancer metastasis.Experimental Design: Next-generation sequencing-based whole-exome sequencing was coupled with reverse-phase protein microarray (RPPA) functional signaling network analysis to explore the PI3K-AKT-mTOR axis in 32 pretreated breast cancer metastases...
August 15, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
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