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JOURNAL ARTICLE
Alexis Carteron, Isabel Cantera, Alessia Guerrieri, Silvio Marta, Aurélie Bonin, Roberto Ambrosini, Fabien Anthelme, Roberto Sergio Azzoni, Peter Almond, Pablo Alviz Gazitúa, Sophie Cauvy-Fraunié, Jorge Luis Ceballos Lievano, Pritam Chand, Milap Chand Sharma, John J Clague, Justiniano Alejo Cochachín Rapre, Chiara Compostella, Rolando Cruz Encarnación, Olivier Dangles, Andre Eger, Sergey Erokhin, Andrea Franzetti, Ludovic Gielly, Fabrizio Gili, Mauro Gobbi, Sigmund Hågvar, Norine Khedim, Rosa Isela Meneses, Gwendolyn Peyre, Francesca Pittino, Antoine Rabatel, Nurai Urseitova, Yan Yang, Vitalii Zaginaev, Andrea Zerboni, Anaïs Zimmer, Pierre Taberlet, Guglielmina Adele Diolaiuti, Jerome Poulenard, Wilfried Thuiller, Marco Caccianiga, Gentile Francesco Ficetola
The development of terrestrial ecosystems depends greatly on plant mutualists such as mycorrhizal fungi. The global retreat of glaciers exposes nutrient-poor substrates in extreme environments and provides a unique opportunity to study early successions of mycorrhizal fungi by assessing their dynamics and drivers. We combined environmental DNA metabarcoding and measurements of local conditions to assess the succession of mycorrhizal communities during soil development in 46 glacier forelands around the globe, testing whether dynamics and drivers differ between mycorrhizal types...
April 6, 2024: New Phytologist
#2
JOURNAL ARTICLE
Ilse Adriana Gutiérrez-Pérez, Ivette Buendía-Roldán, Oscar Zaragoza-García, Gloria Pérez-Rubio, José Rafael Villafan-Bernal, Leslie Chávez-Galán, Isela Parra-Rojas, Rafael de Jesús Hernández-Zenteno, Ingrid Fricke-Galindo, Natividad Castro-Alarcón, Brandon Bautista-Becerril, Ramcés Falfán-Valencia, Iris Paola Guzmán-Guzmán
BACKGROUND: Enzymes of the peptidylarginine deiminase family (PADs) play a relevant role in the pathogenesis of COVID-19. However, the association of single nucleotide polymorphisms (SNPs) in their genes with COVID-19 severity and death is unknown. METHODOLOGY: We included 1045 patients who were diagnosed with COVID-19 between October 2020 and December 2021. All subjects were genotyped for PADI2 (rs1005753 and rs2235926) and PADI4 (rs11203366, rs11203367, and rs874881) SNPs by TaqMan assays and their associations with disease severity, death, and inflammatory biomarkers were evaluated...
March 30, 2024: Heliyon
#3
JOURNAL ARTICLE
Eustorgio S García-Cárdenas, Isela Nuñez-Barrera, América L Miranda-Lora, Juan J Bolaños-Pérez, Rosalinda López-Rodríguez, Norma Briseño-Chavarria, Salvador Villalpando-Carrión
BACKGROUND: Short bowel syndrome (SBS) is one of the most frequent causes of intestinal failure, needing parenteral nutrition to maintain an energy-protein and water-electrolyte balance. At the Hospital Infantil de México Federico Gómez (HIMFG), the formation of two stomas is a technique used for intestinal rehabilitation, where the use of residue through the bypass technique (BT) helps to maintain gastrointestinal functionality, water-electrolyte, and nutritional stability...
2024: Boletín Médico del Hospital Infantil de México
#4
REVIEW
Elda Victoria Rodríguez-Negrete, Ángel Morales-González, Eduardo Osiris Madrigal-Santillán, Karina Sánchez-Reyes, Isela Álvarez-González, Eduardo Madrigal-Bujaidar, Carmen Valadez-Vega, German Chamorro-Cevallos, Luis Fernando Garcia-Melo, José A Morales-González
Inflammation is the immune system's first biological response to infection, injury, or irritation. Evidence suggests that the anti-inflammatory effect is mediated by the regulation of various inflammatory cytokines, such as nitric oxide, interleukins, tumor necrosis factor alpha-α, interferon gamma-γ, as well as the non-cytokine mediator, prostaglandin E2. Currently, the mechanism of action and clinical usefulness of phytochemicals is known; their action on the activity of cytokines, free radicals, and oxidative stress...
February 15, 2024: Plants (Basel, Switzerland)
#5
JOURNAL ARTICLE
Claudio Cabral-Romero, Rene Hernández-Delgadillo, Sergio Eduardo Nakagoshi-Cepeda, Rosa Isela Sánchez-Najéra, Erandi Escamilla-García, Juan Manuel Solís-Soto, Claudia María García-Cuellar, Yesennia Sánchez-Pérez, Samantha Maribel Flores-Treviño, Nayely Pineda-Aguilar, Juan Valerio Cauich-Rodríguez, Irene Meester, Shankararaman Chellam
OBJECTIVE: To evaluate the antitumor and antimicrobial properties of an alginate-based membrane (ABM) loaded with bismuth lipophilic nanoparticles (BisBAL NPs) and cetylpyridinium chloride (CPC) on clinically isolated bacteria and a pancreatic cancer cell line. MATERIAL AND METHODS: The BisBAL NP-CPC ABM was characterized using optical and scanning electron microscopy (SEM). The antimicrobial potential was measured using the disk-diffusion assay, and antibiofilm activity was determined through the live/dead assay and fluorescence microscopy...
2024: Journal of Applied Biomaterials & Functional Materials
#6
JOURNAL ARTICLE
Mario Alberto Alarcón-Sánchez, Natividad Castro-Alarcón, Daniel Sandoval-Guevara, Mirna Vázquez-Villamar, Karla Fernández-Acosta, Mayra Yanet Méndez-Gómez, Isela Parra-Rojas, Norma Samanta Romero-Castro
Prosthetic biomaterials can affect the composition of the subgingival microbiota and consequently the production of proinflammatory cytokines, causing damage to the periodontium. A total of 40 patients were divided into two groups: 20 with monolithic zirconia (MZ) prostheses and 20 with porcelain fused to metal (PFM) with nickel-chromium (Ni-Cr) alloy prostheses. Subgingival plaque and gingival crevicular fluid samples were taken. The Checkerboard technique for DNA-DNA hybridization and the enzyme-linked immunosorbent assay technique were performed...
February 29, 2024: Dental Materials Journal
#7
JOURNAL ARTICLE
José Jaime Martínez-Magaña, Alma Delia Genis-Mendoza, Ileana Gallegos-Silva, María Lilia López-Narváez, Isela Esther Juárez-Rojop, Juan C Diaz-Zagoya, Carlos Alfonso Tovilla-Zárate, Thelma Beatriz González-Castro, Humberto Nicolini, Anayelly Solis-Medina
The use of aspartame (ASP) and potassium acesulfame (ACK) to reduce weight gain is growing; however, contradictory effects in body mass index control and neurobiological alterations resulting from artificial sweeteners consumption have been reported. This study aimed to evaluate the impact of the chronic consumption of ASP and ACK on mood-related behavior and the brain expression of serotonin genes in male Wistar rats. Mood-related behaviors were evaluated using the swim-forced test and defensive burying at two time points: 45 days (juvenile) and 95 days (adult) postweaning...
February 8, 2024: Nutrients
#8
JOURNAL ARTICLE
Melissa Rivera-Escoto, Bertha Campos-López, Karen Pesqueda-Cendejas, Adolfo I Ruiz-Ballesteros, Paulina E Mora-García, Mónica R Meza-Meza, Isela Parra-Rojas, Edith Oregon-Romero, Sergio Cerpa-Cruz, Ulises De la Cruz-Mosso
Rheumatoid arthritis (RA) is a multifactorial autoimmune disease in which hypovitaminosis D by calcidiol quantification has been associated with disease severity. However, other vitamin D molecules could be implicated in RA pathophysiology and its comorbidities such as cardiovascular disease (CVD), which impacts the severity and mortality of RA patients. This study aimed to assess the relationship between calcidiol, calcitriol, its hydroxylation efficiency ratio, and the soluble vitamin D receptor (sVDR) and clinical and CVD risk variables to propose potential vitamin D molecule biomarkers for RA...
January 25, 2024: Biomedicines
#9
JOURNAL ARTICLE
Karla Mayela Bravo-Villagra, José Francisco Muñoz-Valle, Christian Johana Baños-Hernández, Sergio Cerpa-Cruz, José Eduardo Navarro-Zarza, Isela Parra-Rojas, José Alonso Aguilar-Velázquez, Samuel García-Arellano, Andres López-Quintero
Rheumatoid Arthritis (RA) is a multifactorial autoimmune disease. Currently, several genes play an important role in the development of the disease. The objective was to evaluate the association of the STAT4 rs7574865 and rs897200 gene variants with RA susceptibility, DAS28, RF, and anti-CCP in Western and Southern Mexico populations. Genotyping was performed on 476 samples (cases = 240; controls = 236) using the Taqman® system and qPCR probes. Disease activity was assessed using DAS28 and HAQ DI. CRP, ESR, RF, and anti-CCP were determined for clinical assessment...
February 14, 2024: Genes
#10
JOURNAL ARTICLE
Octavio Canales-Alvarez, Maria Margarita Canales-Martinez, Pilar Dominguez-Verano, Daniela Balderas-Cordero, Eduardo Madrigal-Bujaidar, Isela Álvarez-González, Marco Aurelio Rodriguez-Monroy
Diabetes mellitus (DM) affects the wound healing process, resulting in impaired healing or aberrant scarring. DM increases reactive oxygen species (ROS) production, fibroblast senescence and angiogenesis abnormalities, causing exacerbated inflammation accompanied by low levels of TGF-β and an increase in Matrix metalloproteinases (MMPs). Propolis has been proposed as a healing alternative for diabetic patients because it has antimicrobial, anti-inflammatory, antioxidant and proliferative effects and important properties in the healing process...
February 12, 2024: International Journal of Molecular Sciences
#11
Rosa Isela Gálvez, Amparo Martínez-Pérez, E Alexandar Escarrega, Tulika Singh, José Víctor Zambrana, Ángel Balmaseda, Eva Harris, Daniela Weiskopf
Dengue is widespread in tropical and subtropical regions globally and leads to a considerable burden of disease. Annually, dengue virus (DENV) causes up to 400 million infections, of which ~25% present with clinical symptoms ranging from mild to fatal. Despite its significance as a growing public health concern, the development of effective DENV vaccines has been highly challenging. One of the reasons is the lack of comprehensive understanding of the influence exerted by prior DENV infections and immune responses with cross-reactive properties...
February 6, 2024: medRxiv
#12
JOURNAL ARTICLE
Sanchez-Yepez Jonathan, Acevedo-Huergo Triana, Mendoza-Trejo Maria Soledad, Corona Rebeca, Hernandez-Plata Isela, Viñuela-Berni Veronica, Giordano Magda, M Rodríguez Veronica
Several studies have shown that chronic exposure to the herbicide atrazine (ATR) causes alterations in locomotor activity and markers of the dopaminergic systems of male rats. However, few studies have evaluated the sex-dependent effects of atrazine exposure. The aim of the present study was to evaluate whether chronic ATR exposure causes alterations in behavioral performance and dopaminergic systems of female rats. At weaning, two groups of rats were exposed to 1 or 10 mg ATR/kg body weight daily thorough the food, while the control group received food without ATR for 14 months...
February 8, 2024: Neurotoxicology
#13
JOURNAL ARTICLE
Michael Joshue Rendón-Barrón, Eduardo Pérez-Arteaga, Izamary Delgado-Waldo, Jossimar Coronel-Hernández, Carlos Pérez-Plasencia, Frida Rodríguez-Izquierdo, Rosa Linares, Alma Rosa González-Esquinca, Isela Álvarez-González, Eduardo Madrigal-Bujaidar, Nadia Judith Jacobo-Herrera
Colorectal cancer (CRC) is the third most common neoplasia in the world. Its mortality rate is high due to the lack of specific and effective treatments, metastasis, and resistance to chemotherapy, among other factors. The natural products in cancer are a primary source of bioactive molecules. In this research, we evaluated the antitumor activity of an acetogenin (ACG), laherradurin (LH), isolated from the Mexican medicinal plant Annona macroprophyllata Donn.Sm. in a CRC murine model. The CRC was induced by azoxymethane-dextran sulfate sodium (AOM/DSS) in Balb/c mice and treated for 21 days with LH or cisplatin...
January 29, 2024: Cancers
#14
JOURNAL ARTICLE
Alessia Guerrieri, Isabel Cantera, Silvio Marta, Aurélie Bonin, Alexis Carteron, Roberto Ambrosini, Marco Caccianiga, Fabien Anthelme, Roberto Sergio Azzoni, Peter Almond, Pablo Alviz Gazitúa, Sophie Cauvy-Fraunié, Jorge Luis Ceballos Lievano, Pritam Chand, Milap Chand Sharma, John Clague, Justiniano Alejo Cochachín Rapre, Chiara Compostella, Rolando Cruz Encarnación, Olivier Dangles, Philip Deline, Andre Eger, Sergey Erokhin, Andrea Franzetti, Ludovic Gielly, Fabrizio Gili, Mauro Gobbi, Sigmund Hågvar, Norine Khedim, Rosa Isela Meneses, Gwendolyn Peyre, Francesca Pittino, Angela Proietto, Antoine Rabatel, Nurai Urseitova, Yan Yang, Vitalii Zaginaev, Andrea Zerboni, Anaïs Zimmer, Pierre Taberlet, Guglielmina Adele Diolaiuti, Jerome Poulenard, Diego Fontaneto, Wilfried Thuiller, Gentile Francesco Ficetola
The worldwide retreat of glaciers is causing a faster than ever increase in ice-free areas that are leading to the emergence of new ecosystems. Understanding the dynamics of these environments is critical to predicting the consequences of climate change on mountains and at high latitudes. Climatic differences between regions of the world could modulate the emergence of biodiversity and functionality after glacier retreat, yet global tests of this hypothesis are lacking. Nematodes are the most abundant soil animals, with keystone roles in ecosystem functioning, but the lack of global-scale studies limits our understanding of how the taxonomic and functional diversity of nematodes changes during the colonization of proglacial landscapes...
January 2024: Global Change Biology
#15
JOURNAL ARTICLE
Ma Elena Moreno-Godínez, Eugenia Flores-Alfaro, Isela Parra-Rojas, Irma Martha Medina-Diaz, Aurora Elizabeth Rojas-García, Cristian Avilés-Ramírez, Gabriela Campos-Viguri, Marco Antonio Ramírez-Vargas
OBJETIVE: To provide a comprehensive analysis of mortality trends from acute pesticide poisoning in Mexico from 2000 through 2021. METHODS: The governmental records of deaths from acute pesticide poisoning were used. The age-standardized years of life lost and aged-standardized mortality rates were estimated. Significant changes in trends of annual percentage change were identified using Joinpoint regression. RESULTS: Between 2000 and 2021, mortality was primarily observed in individuals aged 15 to 19 years...
2024: Brazilian Journal of Epidemiology
#16
JOURNAL ARTICLE
Reséndiz-Jiménez Arely, Arbez-Evangelista Cristian, Arroyo-Xochihua Omar, Palma-Jacinto José Antonio, Santiago-Roque Isela, De León-Ramírez Yeimy Mar, Hernández-Domínguez Xcaret Alexa, Arroyo-Helguera Omar
BACKGROUND: Epidemiological clinical reports have shown an association between iodine excess with diabetes mellitus type 2 and higher blood glucose. However, the relationship between iodine, the pancreas, adipose tissue, and glucose transport is unclear. The goal of this study was to analyze the effect of iodine concentrations (in Lugol solution) on glucose transport, insulin secretion, and its cytotoxic effects in mature 3T3-L1 adipocytes and pancreatic beta-TC-6 cells. METHODS: Fibroblast 3T3-L1, mature adipocytes, and pancreatic beta-TC-6 cells were treated with 1 to 1000 µM of Lugol (molecular iodine dissolved in potassium iodide) for 30 min to 24 h for an MTT proliferation assay...
January 1, 2024: Biology
#17
JOURNAL ARTICLE
Isabel Cantera, Alexis Carteron, Alessia Guerrieri, Silvio Marta, Aurélie Bonin, Roberto Ambrosini, Fabien Anthelme, Roberto Sergio Azzoni, Peter Almond, Pablo Alviz Gazitúa, Sophie Cauvy-Fraunié, Jorge Luis Ceballos Lievano, Pritam Chand, Milap Chand Sharma, John Clague, Justiniano Alejo Cochachín Rapre, Chiara Compostella, Rolando Cruz Encarnación, Olivier Dangles, Andre Eger, Sergey Erokhin, Andrea Franzetti, Ludovic Gielly, Fabrizio Gili, Mauro Gobbi, Sigmund Hågvar, Norine Khedim, Rosa Isela Meneses, Gwendolyn Peyre, Francesca Pittino, Antoine Rabatel, Nurai Urseitova, Yan Yang, Vitalii Zaginaev, Andrea Zerboni, Anaïs Zimmer, Pierre Taberlet, Guglielmina Adele Diolaiuti, Jerome Poulenard, Wilfried Thuiller, Marco Caccianiga, Gentile Francesco Ficetola
The mechanisms underlying plant succession remain highly debated. Due to the local scope of most studies, we lack a global quantification of the relative importance of species addition 'versus' replacement. We assessed the role of these processes in the variation (β-diversity) of plant communities colonizing the forelands of 46 retreating glaciers worldwide, using both environmental DNA and traditional surveys. Our findings indicate that addition and replacement concur in determining community changes in deglaciated sites, but their relative importance varied over time...
January 17, 2024: Nature Plants
#18
JOURNAL ARTICLE
José Manuel Fragoso, Gilberto Vargas-Alarcón, Ángel Emanuel Martínez-Flores, Isela Montufar-Robles, Rosa Elda Barbosa-Cobos, Gustavo Rojas-Velazco, Julian Ramírez-Bello
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for causing coronavirus disease 2019 (COVID-19). The development and severity of this infectious disease is influenced by a combination of environmental and genetic factors. Angiotensin-converting enzyme 2 (ACE2) facilitates SARS-CoV-2 entry into human cells, with transmembrane serine protease 2 (TMPRSS2) playing a crucial role in S protein priming. Other proteases, such as cathepsin L and elastase, neutrophil-expressed (ELANE), have the capability to prime the S protein and contribute to SARS-CoV-2 infection...
January 15, 2024: Biomol Biomed
#19
JOURNAL ARTICLE
Jesús Contreras Mendoza, Enrique Arriola Guevara, Luis Antonio Suarez Hernández, Guillermo Toriz, Guadalupe María Guatemala-Morales, Rosa Isela Corona-González
Mango processing generates significant amounts of residues (35-65%) that may represent environmental problems owed to improper disposal. The use of mango byproducts as substrates to produce hyaluronic acid (HA) is an attractive alternative to reduce the cost of substrate. In this study, we evaluated the potential of hydrolyzates from mango peels and seeds to produce HA by Streptococcus equi. subsp. zooepidemicus. The physicochemical characterization of mango residues showed that the seeds contain a higher amount of holocellulose (cellulose and hemicellulose), which amounts 54...
January 5, 2024: Folia Microbiologica
#20
JOURNAL ARTICLE
José Alberto Patiño-Medina, Viridiana Alejandre-Castañeda, Marco Iván Valle-Maldonado, Mauro Manuel Martínez-Pacheco, León Francisco Ruiz-Herrera, Joel Ramírez-Emiliano, Oscar Abelardo Ramírez-Marroquín, Karla Viridiana Castro-Cerritos, Jesús Campos-García, Martha Isela Ramírez-Díaz, Victoriano Garre, Ulrike Binder, Víctor Meza-Carmen
This study analyzed the role of blood serum in enhancing the mitochondrial metabolism and virulence of Mucorales through rhizoferrin secretion. We observed that the spores of clinically relevant Mucorales produced in the presence of serum exhibited higher virulence in a heterologous infection model of Galleria mellonella . Cell-free supernatants of the culture broth obtained from spores produced in serum showed increased toxicity against Caenorhabditis elegans , which was linked with the enhanced secretion of rhizoferrin...
November 22, 2023: Journal of Fungi (Basel, Switzerland)
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