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Diana Isela Araujo-Espino, Ana Lourdes Zamora-Perez, Guillermo Moisés Zúñiga-González, Rosalinda Gutiérrez Hernández, Gabriela Morales-Velazquez, Blanca Patricia Lazalde-Ramos
Jatropha dioica Sessé ex Cerv. is a medicinal plant credited with low cytotoxicity in vitro. Thus, the objective of this work was to evaluate the possible genotoxic and cytotoxic effect in vivo of the J. dioica aqueous extract by means of micronucleus assay in mouse peripheral blood. Four different J. dioica aqueous extract dose-units were evaluated (30, 60, 100, and 300 mg/kg). The extract was administered orally to male Balb-C-strain mice every 24 h during 5 days. Blood samples were taken at 0, 24, 48, 72, 96, and 120 h from the mouse's tail and were performed in duplicate extensions...
March 22, 2017: Regulatory Toxicology and Pharmacology: RTP
Patricia Bustos, Rosa Isela Santamaría, Olga María Pérez-Carrascal, José Luis Acosta, Luis Lozano, Soledad Juárez, Irma Martínez-Flores, Esperanza Martínez-Romero, Miguel Ángel Cevallos, David Romero, Guillermo Dávila, Pablo Vinuesa, Fabiola Miranda, Ernesto Ormeño, Víctor González
The whole-genome sequences of three strains of Rhizobium gallicum reported here support the concept that the distinct nodulation host ranges displayed by the symbiovars gallicum and phaseoli can be largely explained by different symbiotic plasmids.
March 16, 2017: Genome Announcements
José Francisco Muñoz-Valle, Jorge Ramón Padilla-Gutiérrez, Jorge Hernández-Bello, Yeniley Ruiz-Noa, Yeminia Valle, Claudia Azucena Palafox-Sánchez, Isela Parra-Rojas, Sergio Ramón Gutiérrez-Ureña, Hector Rangel-Villalobos
BACKGROUND AND OBJECTIVES: The protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene encodes an important negative regulator of T-cell activation, lymphoid-specific phosphatase -Lyp- and has been associated with different autoimmune disorders. The PTPN22 -1123G>C polymorphism appears to affect the transcriptional control of this gene, but to date, the biological significance of this polymorphisms on rheumatoid arthritis (RA) risk remains unknown. We evaluate the association of PTPN22 -1123G>C polymorphism with anti-cyclic citrullinated protein antibodies (anti-CCP) and risk for RA in population from Western Mexico...
March 10, 2017: Medicina Clínica
Karely Pulido-Gómez, Yazmín Hernández-Díaz, Carlos Alfonso Tovilla-Zárate, Isela Esther Juárez-Rojop, Thelma Beatriz González-Castro, María Lilia López-Narváez, Mariela Alpuin-Reyes
BACKGROUND AND AIMS: It is widely acknowledged that coronary heart disease (CHD) has a genetic influence. One of the most promising candidate genes is tumor necrosis factor-alpha (TNF-α). Although there have been several positive studies associating the TNF-α gene and CHD, the evidence is not entirely consistent. The aim of the study was to evaluate the role of the TNF-α gene in CHD using combined evidence by generating a meta-analysis and a systematic review of all published data...
October 2016: Archives of Medical Research
Gabriel Molina-Guzman, Thelma Beatriz González-Castro, Yazmín Hernández Díaz, Carlos Alfonso Tovilla-Zárate, Isela E Juárez-Rojop, Crystell Guadalupe Guzmán-Priego, Alma Genis, Sherezada Pool García, María Lilia López-Narvaez, José Manuel Rodriguez-Perez
BACKGROUND: The aim of this case-control study was to explore the association by gender between the HTR2C gene variants and suicidal behavior in a Mexican population. SUBJECTS AND METHODS: A total of 183 suicide attempters and 208 healthy volunteers were included in this study. We genotyped five polymorphisms of HTR2C (rs547536, rs2192372, rs4272555, rs6318, and rs2428707), then measured the association by genotype, allele, and haplotype. RESULTS: In the female group, we found an association between two polymorphisms of the HTR2C (rs4272555 and rs2428707) and suicide attempts...
2017: Neuropsychiatric Disease and Treatment
Teresa Domínguez-Reyes, Irma Quiroz-Vargas, Aralia Berenice Salgado-Bernabé, Lorenzo Salgado-Goytia, José Francisco Muñoz-Valle, Isela Parra-Rojas
Introducción: actualmente se considera que la acumulación de grasa corporal a nivel central se asocia con la presencia de hipertrigliceridemia, hipertensión arterial y diabetes. El índice de masa corporal (IMC) se ha utilizado para identificar la obesidad en la población general, pero no permite determinar la distribución de la grasa corporal, por lo que se pueden utilizar otras medidas antropométricas para evaluar la adiposidad y determinar su relación con la presencia de alteraciones metabólicas que presentan las personas con exceso de peso...
February 1, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Ezequiel Hernández-Becerra, Elsa Gutiérrez-Cortez, Alicia Del Real, Alejandra Rojas-Molina, Mario Rodríguez-García, Efraín Rubio, Michelle Quintero-García, Isela Rojas-Molina
Mechanical, microstructural properties, mineral content and bone mineral density (BMD) of the femur were evaluated in growing rats fed with Opuntia ficus indica (L.) Mill. (Cactaceae) cladodes at different maturity stages as calcium source. Male weanling rats were fed with cladodes at early maturity stage (25 and 60 days of age, belonging to groups N-60 and N-200, respectively) and cladodes at late maturity stage (100 and 135 days of age, belonging to groups N-400 and N-600, respectively) for 6 weeks. Additionally, a control group fed with calcium carbonate as calcium source was included for comparative purposes...
February 4, 2017: Nutrients
Randall Phelps, Anne Tsai, Arlene Hagen, Joseph Pinter, Raegan Smith, Martin T Stein
Isela is an 11-year-old Mexican-American girl with mild intellectual disability. During a vacation with her family, she went swimming with dolphins. A few days later, Isela awoke at night with laughing spells; during the day, she was pacing, aggressive, and had a decline in self-care and communication skills. Her parents attributed the symptoms to the dolphins. She was evaluated by a pediatric neurologist. The sleep-deprived electroencephalogram, brain magnetic resonance imaging, lumbar puncture, and thyroid function tests were normal...
February 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
Yolanda Cruz, Isela Hernández-Plata, Rosa Angélica Lucio, René Zempoalteca, Francisco Castelán, Margarita Martínez-Gómez
AIM: To determine the anatomical organization and somatic axonal components of the lumbosacral nerves in female rabbits. METHODS: Chinchilla adult anesthetized female rabbits were used. Anatomical, electrophysiological, and histological studies were performed. RESULTS: L7, S1, and some fibers from S2 and S3 form the lumbosacral trunk, which gives origin to the sciatic nerve and innervation to the gluteal region. From S2 to S3 originates the pudendal nerve, whose branches innervates the striated anal and urethra sphincters, as well as the bulbospongiosus, ischiocavernosus, and constrictor vulvae muscles...
January 19, 2017: Neurourology and Urodynamics
Rosa Isela Guzmán-Gerónimo, Tania Margarita Alarcón-Zavaleta, Rosa María Oliart-Ros, José Enrique Meza-Alvarado, Socorro Herrera-Meza, José Luis Chávez-Servia
The effect of blue maize extract in factors related to metabolic syndrome (MS) in Wistar rats was investigated. Total polyphenols, monomeric anthocyanins, and antioxidant activity were analyzed in blue maize. MS was induced in Wistar rats fed with high-sucrose (HS) diet for 12 weeks. During a period of 4 weeks, blue maize extract was administrated to HS groups fed with high-sucrose and high-cholesterol-high-sucrose (HS+C) diets. In the blue maize extract administered by orogastric cannulation, the levels of total polyphenols and anthocyanins were 9...
February 2017: Journal of Medicinal Food
Yazmín Hernández-Díaz, Carlos Alfonso Tovilla-Zárate, Isela Esther Juárez-Rojop, Thelma Beatriz González-Castro, Candelario Rodríguez-Pérez, María Lilia López-Narváez, José Manuel Rodríguez-Pérez, José Francisco Cámara-Álvarez
BACKGROUND: Associations between paraoxonase 1 (PON1) gene polymorphisms and heart diseases (HD) risk remain inconsistent. In order to obtain address this issue we performed a meta-analysis to assess the association between the L55M and Q192R polymorphisms of PON1 gene and heart diseases risk. METHODS: Relevant studies were enrolled by searching databases systematically. Odds ratios (ORs) with 95% confidence intervals (CIs) were used to calculate the strength of association...
November 2016: Medicine (Baltimore)
Lineth J Vega Rojas, Isela Rojas Molina, Elsa Gutiérrez Cortez, Natalia Rincón Londoño, Andrés A Acosta Osorio, Alicia Del Real López, Mario E Rodríguez García
This research studied the influence of the germ components on the physicochemical properties of cooked corn and nixtamalized corn flours as a function of the calcium hydroxide content (from 0 to 2.1 w/w) and steeping time (between 0 and 9h). A linear relationship was found between calcium content in germ and steeping time used during nixtamalization process. X-ray diffraction analysis showed that calcium carbonate is formed into the germ structure to 2.1 w/w of calcium hydroxide and 9h steeping time. The presence of the germ improves the development of peak viscosity in flours, and it is related to the increases in calcium concentration in germ and the formation of amylose-lipid complexes...
April 1, 2017: Food Chemistry
Thelma Beatriz González-Castro, Yazmín Hernández-Díaz, Isela Esther Juárez-Rojop, María Lilia López-Narváez, Carlos Alfonso Tovilla-Zárate, Alma Genis-Mendoza, Mariela Alpuin-Reyes
BACKGROUND: The association between the dopamine D2 receptor (DRD2) gene and schizophrenia has been studied though no conclusive outcomes have been attained. The aim of this study was to perform a systematic review and meta-analysis to explore the relation between three polymorphisms of the DRD2 gene (C957T, TaqI and Ser311Cys) and schizophrenia. METHODS: The search was made in PubMed and EBSCO databases (up to February 2016). The systematic review included 34 case-control association studies (34 for C957T, 16 for TaqI and 36 for Ser311Cys)...
November 9, 2016: Behavioral and Brain Functions: BBF
Verónica Fernández-Arteaga, Carlos Alfonso Tovilla-Zárate, Ana Fresán, Thelma Beatriz González-Castro, Isela E Juárez-Rojop, Lilia López-Narváez, Yazmín Hernández-Díaz
BACKGROUND AND OBJECTIVE: Suicide is a worldwide health problem and climatological characteristics have been associated with suicide behavior. However, approaches such as the Knowledge Discovery in Database are not frequently used to search for an association between climatological characteristics and suicide. The aim of the present study was to assess the association between weather data and suicide in a Mexican population. METHODS: We used the information of 1357 patients who completed suicide from 2005 to 2012...
October 2016: Computer Methods and Programs in Biomedicine
Iris Paola Guzmán-Guzmán, Oscar Zaragoza-García, Amalia Vences-Velázquez, Natividad Castro-Alarcón, José Francisco Muñoz-Valle, Isela Parra-Rojas
INTRODUCTION: Inflammation and endothelial dysfunction are considered the primary manifestations of the cardiovascular disease. Studies have established a relationship among components of metabolic syndrome (MetS) with inflammatory markers and the loss of permeability, vasoconstriction and vasodilatation endothelial. OBJECTIVE: To determine the relationship among the concentrations of soluble endothelial dysfunction molecules and inflammation cytokines and components of the metabolic syndrome in young population...
November 18, 2016: Medicina Clínica
Norma Isela Vizuet Vega, Teresa Shamah Levy, Elsa Berenice Gaona Pineda, Lucía Cuevas Nasu, Ignacio Méndez Gómez-Humarán
Introducción: la anemia es un factor de riesgo en la población infantil con consecuencias graves para su crecimiento y desarrollo. Los programas de ayuda alimentaria pueden contribuir a su prevención y control. Objetivo: estudiar la adherencia al consumo de suplementos y su relación con la prevalencia de anemia en niños menores de tres años de edad en San Luis Potosí, México beneficiarios del programa PROSPERA.Métodos: se realizó un análisis comparativo en niños de 12 a 36 meses que consumen diferentes suplementos alimenticios: 414 pertenecientes al grupo de intervención y 334 al de comparación...
July 19, 2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Inmaculada de la Calle, Francisco Pena-Pereira, Isela Lavilla, Carlos Bendicho
An overview of the combination of liquid-phase microextraction (LPME) techniques with graphite furnace atomic absorption spectrometry (GFAAS) is reported herein. The high sensitivity of GFAAS is significantly enhanced by its association with a variety of miniaturized solvent extraction approaches. LPME-GFAAS thus represents a powerful combination for determination of metals, metalloids and organometallic compounds at (ultra)trace level. Different LPME modes used with GFAAS are briefly described, and the experimental parameters that show an impact in those microextraction processes are discussed...
September 14, 2016: Analytica Chimica Acta
María Conchita Ocaña-Zurita, Isela E Juárez-Rojop, Alma Genis, Carlos Alfonso Tovilla-Zárate, Thelma Beatriz González-Castro, María Lilia López-Narváez, María Elena de la O de la O, Humberto Nicolini
OBJECTIVE: The aim of this study was to observe potential drug-drug interactions in the medication of Mexican schizophrenic patients. METHODS: We performed a retrospective and cross-sectional study that was carried out in a psychiatric clinic. Only the prescriptions of patients with schizophrenia whose diagnoses were based on the DSM-IV instrument were included in this study. The Drug Interactions Checker software ( ) was used in this study to analyse potential drug-drug interactions...
November 2016: International Journal of Psychiatry in Clinical Practice
Gerardo Daniel Sierra Garcia, Rosa Isela Sanchez Najera, Sergio Eduardo Nakagoshi Cepeda, Jorge Jaime Flores Treviño, Catalina Lopez Ruiz
No abstract text is available yet for this article.
June 2016: Journal of Clinical and Diagnostic Research: JCDR
Ana Fresán, Beatriz Camarena, Thelma Beatriz González-Castro, Carlos Alfonso Tovilla-Zárate, Isela E Juárez-Rojop, Lilia López-Narváez, Alicia E González-Ramón, Yazmín Hernández-Díaz
BACKGROUND: The present study compared sociodemographic characteristics, comorbidities with substance use, and impulsivity features in three groups of psychiatric patients - suicide attempters, nonsuicidal self-injury, and nonsuicidal without self-injury - to determine the predictive factors for nonsuicidal self-injury or suicide behavior. PATIENTS AND METHODS: Demographic features and self-reported substance use were assessed in 384 Mexican psychiatric patients...
2016: Neuropsychiatric Disease and Treatment
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