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https://www.readbyqxmd.com/read/29353213/multiple-cortical-thickness-sub-networks-and-cognitive-impairments-in-first-episode-drug-na%C3%A3-ve-patients-with-late-life-depression-a-graph-theory-analysis
#1
Jeong-Hyeon Shin, Yu Hyun Um, Chang Uk Lee, Hyun Kook Lim, Joon-Kyung Seong
BACKGROUND: Coordinated and pattern-wise changes in large scale gray matter structural networks reflect neural circuitry dysfunction in late life depression (LLD), which in turn is associated with emotional dysregulation and cognitive impairments. However, due to methodological limitations, there have been few attempts made to identify individual-level structural network properties or sub-networks that are involved in important brain functions in LLD. METHODS: In this study, we sought to construct individual-level gray matter structural networks using average cortical thicknesses of several brain areas to investigate the characteristics of the gray matter structural networks in normal controls and LLD patients...
January 5, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29352255/offline-stimulation-of-human-parietal-cortex-differently-affects-resting-eeg-microstates
#2
Pierpaolo Croce, Filippo Zappasodi, Paolo Capotosto
The interference effects of transcranial magnetic stimulation (TMS) on several electroencephalographic (EEG) measures in both temporal and frequency domains have been reported. We tested the hypothesis whether the offline external inhibitory interference, although focal, could result in a global reorganization of the functional brain state, as assessed by EEG microstates. In 16 healthy subjects, we inhibited five parietal areas and used a pseudo stimulation (Sham) at rest. The EEG microstates were extracted before and after each stimulation...
January 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29352028/the-mysteries-of-remote-memory
#3
REVIEW
Zimbul Albo, Johannes Gräff
Long-lasting memories form the basis of our identity as individuals and lie central in shaping future behaviours that guide survival. Surprisingly, however, our current knowledge of how such memories are stored in the brain and retrieved, as well as the dynamics of the circuits involved, remains scarce despite seminal technical and experimental breakthroughs in recent years. Traditionally, it has been proposed that, over time, information initially learnt in the hippocampus is stored in distributed cortical networks...
March 19, 2018: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/29350187/multifractal-dynamics-of-resting-state-functional-connectivity-in-the-prefrontal-cortex
#4
Frigyes Samuel Racz, Peter Mukli, Zoltan Nagy, Andras Eke
Brain function is organized as a network of functional connections between different neuronal populations with connection strengths dynamically changing in time and space. Studies investigating functional connectivity (FC) usually follow a static approach when describing FC by considering the connectivity strengths constant, however a dynamic approach seems more reasonable, as this way the spatio-temporal dynamics of the underlying system can also be captured. Objective: The scale-free, i.e. fractal nature of neural dynamics is an inherent property of the nervous system...
January 19, 2018: Physiological Measurement
https://www.readbyqxmd.com/read/29349880/beyond-the-realist-turn-a-socio-material-analysis-of-heart-failure-self-care
#5
Allan McDougall, Elizabeth Anne Kinsella, Mark Goldszmidt, Karen Harkness, Patricia Strachan, Lorelei Lingard
For patients living with chronic illnesses, self-care has been linked with positive outcomes such as decreased hospitalisation, longer lifespan, and improved quality of life. However, despite calls for more and better self-care interventions, behaviour change trials have repeatedly fallen short on demonstrating effectiveness. The literature on heart failure (HF) stands as a case in point, and a growing body of HF studies advocate realist approaches to self-care research and policymaking. We label this trend the 'realist turn' in HF self-care...
January 2018: Sociology of Health & Illness
https://www.readbyqxmd.com/read/29349465/exploring-candidate-biomarkers-for-lung-and-prostate-cancers-using-gene-expression-and-flux-variability-analysis
#6
Yazdan Asgari, Pegah Khosravi, Zahra Zabihinpour, Mahnaz Habibi
Genome-scale metabolic models have provided valuable resources for exploring changes in metabolism under normal and cancer conditions. However, metabolism itself is strongly linked to gene expression, so integration of gene expression data into metabolic models might improve the detection of genes involved in the control of tumor progression. Herein, we considered gene expression data as extra constraints to enhance the predictive powers of metabolic models. We reconstructed genome-scale metabolic models for lung and prostate, under normal and cancer conditions to detect the major genes associated with critical subsystems during tumor development...
January 19, 2018: Integrative Biology: Quantitative Biosciences From Nano to Macro
https://www.readbyqxmd.com/read/29349447/theoretical-study-on-the-charge-transport-in-single-crystals-of-tcnq-f2-tcnq-and-f4-tcnq
#7
Li-Fei Ji, Jian-Xun Fan, Shou-Feng Zhang, Ai-Min Ren
2,5-Difluoro-7,7,8,8-tetracyanoquinodimethane (F2-TCNQ) was recently reported to display excellent electron transport properties in single crystal field-effect transistors (FETs). Its carrier mobility can reach 25 cm2 V-1 s-1 in devices. However, its counterparts TCNQ and F4-TCNQ (tetrafluoro-7,7,8,8-tetracyanoquinodimethane) do not exhibit the same highly efficient behavior. To better understand this significant difference in charge carrier mobility, a multiscale approach combining semiclassical Marcus hopping theory, a quantum nuclear enabled hopping model and molecular dynamics simulations was performed to assess the electron mobilities of the Fn-TCNQ (n = 0, 2, 4) systems in this work...
January 19, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29349278/machine-learning-approaches-to-the-social-determinants-of-health-in-the-health-and-retirement-study
#8
Benjamin Seligman, Shripad Tuljapurkar, David Rehkopf
Background: Social and economic factors are important predictors of health and of recognized importance for health systems. However, machine learning, used elsewhere in the biomedical literature, has not been extensively applied to study relationships between society and health. We investigate how machine learning may add to our understanding of social determinants of health using data from the Health and Retirement Study. Methods: A linear regression of age and gender, and a parsimonious theory-based regression additionally incorporating income, wealth, and education, were used to predict systolic blood pressure, body mass index, waist circumference, and telomere length...
April 2018: SSM—Population Health
https://www.readbyqxmd.com/read/29348728/systems-level-mechanisms-of-action-of-panax-ginseng-a-network-pharmacological-approach
#9
REVIEW
Sa-Yoon Park, Ji-Hun Park, Hyo-Su Kim, Choong-Yeol Lee, Hae-Jeung Lee, Ki Sung Kang, Chang-Eop Kim
Panax ginseng has been used since ancient times based on the traditional Asian medicine theory and clinical experiences, and currently, is one of the most popular herbs in the world. To date, most of the studies concerning P. ginseng have focused on specific mechanisms of action of individual constituents. However, in spite of many studies on the molecular mechanisms of P. ginseng, it still remains unclear how multiple active ingredients of P. ginseng interact with multiple targets simultaneously, giving the multidimensional effects on various conditions and diseases...
January 2018: Journal of Ginseng Research
https://www.readbyqxmd.com/read/29348041/executive-dysfunction-in-autism-spectrum-disorder-is-associated-with-a-failure-to-modulate-frontoparietal-insular-hub-architecture
#10
Charles J Lynch, Andrew L Breeden, Xiaozhen You, Ruth Ludlum, William D Gaillard, Lauren Kenworthy, Chandan J Vaidya
BACKGROUND: Comorbid executive dysfunction in autism spectrum disorder (ASD) is a barrier to adaptive functioning, despite remittance of core social-communication symptoms. Network models of ASD address core symptoms but not comorbid executive dysfunction. Following recent demonstrations in healthy adults that, with increasing executive demands, hubs embedded within frontoparietal-insular control networks interact with a more diverse set of networks, we hypothesized that the capability of hubs to do so is perturbed in ASD and predicts executive behavior...
September 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/29347790/finite-connected-components-in-infinite-directed-and-multiplex-networks-with-arbitrary-degree-distributions
#11
Ivan Kryven
This work presents exact expressions for size distributions of weak and multilayer connected components in two generalizations of the configuration model: networks with directed edges and multiplex networks with an arbitrary number of layers. The expressions are computable in a polynomial time and, under some restrictions, are tractable from the asymptotic theory point of view. If first partial moments of the degree distribution are finite, the size distribution for two-layer connected components in multiplex networks exhibits an exponent -3/2 in the critical regime, whereas the size distribution of weakly connected components in directed networks exhibits two critical exponents -1/2 and -3/2...
November 2017: Physical Review. E
https://www.readbyqxmd.com/read/29347732/population-equations-for-degree-heterogenous-neural-networks
#12
M Kähne, I M Sokolov, S Rüdiger
We develop a statistical framework for studying recurrent networks with broad distributions of the number of synaptic links per neuron. We treat each group of neurons with equal input degree as one population and derive a system of equations determining the population-averaged firing rates. The derivation rests on an assumption of a large number of neurons and, additionally, an assumption of a large number of synapses per neuron. For the case of binary neurons, analytical solutions can be constructed, which correspond to steps in the activity versus degree space...
November 2017: Physical Review. E
https://www.readbyqxmd.com/read/29347657/mapping-of-the-bak-tang-and-wiesenfeld-sandpile-model-on-a-two-dimensional-ising-correlated-percolation-lattice-to-the-two-dimensional-self-avoiding-random-walk
#13
J Cheraghalizadeh, M N Najafi, H Dashti-Naserabadi, H Mohammadzadeh
The self-organized criticality on the random fractal networks has many motivations, like the movement pattern of fluid in the porous media. In addition to the randomness, introducing correlation between the neighboring portions of the porous media has some nontrivial effects. In this paper, we consider the Ising-like interactions between the active sites as the simplest method to bring correlations in the porous media, and we investigate the statistics of the BTW model in it. These correlations are controlled by the artificial "temperature" T and the sign of the Ising coupling...
November 2017: Physical Review. E
https://www.readbyqxmd.com/read/29347603/asymmetric-noise-induced-large-fluctuations-in-coupled-systems
#14
Ira B Schwartz, Klimka Szwaykowska, Thomas W Carr
Networks of interacting, communicating subsystems are common in many fields, from ecology, biology, and epidemiology to engineering and robotics. In the presence of noise and uncertainty, interactions between the individual components can lead to unexpected complex system-wide behaviors. In this paper, we consider a generic model of two weakly coupled dynamical systems, and we show how noise in one part of the system is transmitted through the coupling interface. Working synergistically with the coupling, the noise on one system drives a large fluctuation in the other, even when there is no noise in the second system...
October 2017: Physical Review. E
https://www.readbyqxmd.com/read/29347563/importance-of-small-degree-nodes-in-assortative-networks-with-degree-weight-correlations
#15
Sijuan Ma, Ling Feng, Christopher Pineda Monterola, Choy Heng Lai
It has been known that assortative network structure plays an important role in spreading dynamics for unweighted networks. Yet its influence on weighted networks is not clear, in particular when weight is strongly correlated with the degrees of the nodes as we empirically observed in Twitter. Here we use the self-consistent probability method and revised nonperturbative heterogenous mean-field theory method to investigate this influence on both susceptible-infective-recovered (SIR) and susceptible-infective-susceptible (SIS) spreading dynamics...
October 2017: Physical Review. E
https://www.readbyqxmd.com/read/29347560/effect-of-capillary-condensation-on-gas-transport-properties-in-porous-media
#16
Yuta Yoshimoto, Takuma Hori, Ikuya Kinefuchi, Shu Takagi
We investigate the effect of capillary condensation on gas diffusivity in porous media composed of randomly packed spheres with moderate wettability. To simulate capillary phenomena at the pore scale while retaining complex pore networks of the porous media, we employ density functional theory (DFT) for coarse-grained lattice gas models. The lattice DFT simulations reveal that capillary condensations preferentially occur at confined pores surrounded by solid walls, leading to the occlusion of narrow pores. Consequently, the characteristic lengths of the partially wet structures are larger than those of the corresponding dry structures with the same porosities...
October 2017: Physical Review. E
https://www.readbyqxmd.com/read/29347554/action-at-a-distance-in-classical-uniaxial-ferromagnetic-arrays
#17
D B Abraham, A Maciołek, A Squarcini, O Vasilyev
We examine in detail the theoretical foundations of striking long-range couplings emerging in arrays of fluid cells connected by narrow channels by using a lattice gas (Ising model) description of a system. We present a reexamination of the well known exact determination of the two-point correlation function along the edge of a channel using the transfer matrix technique and a different interpretation is provided. The explicit form of the correlation length is found to grow exponentially with the cross section of the channels at the bulk two-phase coexistence...
October 2017: Physical Review. E
https://www.readbyqxmd.com/read/29347511/design-of-coupling-parameters-for-inducing-amplitude-death-in-cartesian-product-networks-of-delayed-coupled-oscillators
#18
Yoshiki Sugitani, Keiji Konishi
The present study investigates amplitude death in Cartesian product networks of two subnetworks, where each subnetwork has a different coupling delay. The property of the Cartesian product helps us to analyze the stability of amplitude death. Our analysis reveals that amplitude death can occur for long coupling delays if there is a suitable difference in the coupling delays in the two subnetworks. Furthermore, based on the edge theorem in robust control theory, we propose two design procedures of coupling parameters for inducing amplitude death in the Cartesian product networks...
October 2017: Physical Review. E
https://www.readbyqxmd.com/read/29347385/organization-and-scaling-in-water-supply-networks
#19
Likwan Cheng, Bryan W Karney
Public water supply is one of the society's most vital resources and most costly infrastructures. Traditional concepts of these networks capture their engineering identity as isolated, deterministic hydraulic units, but overlook their physics identity as related entities in a probabilistic, geographic ensemble, characterized by size organization and property scaling. Although discoveries of allometric scaling in natural supply networks (organisms and rivers) raised the prospect for similar findings in anthropogenic supplies, so far such a finding has not been reported in public water or related civic resource supplies...
December 2017: Physical Review. E
https://www.readbyqxmd.com/read/29347353/theory-of-nonstationary-hawkes-processes
#20
Neta Ravid Tannenbaum, Yoram Burak
We expand the theory of Hawkes processes to the nonstationary case, in which the mutually exciting point processes receive time-dependent inputs. We derive an analytical expression for the time-dependent correlations, which can be applied to networks with arbitrary connectivity, and inputs with arbitrary statistics. The expression shows how the network correlations are determined by the interplay between the network topology, the transfer functions relating units within the network, and the pattern and statistics of the external inputs...
December 2017: Physical Review. E
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