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Compartement syndrome

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https://www.readbyqxmd.com/read/28934539/popliteal-artery-entrapment-syndrome-bilateral-lower-extremity-involvement
#1
Havalee T Henry, Lauren K Szolomayer, Bauer E Sumpio, Karen M Sutton
Popliteal artery entrapment syndrome is a condition in which compression of the popliteal neurovascular structures results in symptoms of lower extremity claudication by way of a constricting anatomic structure or a hypertrophied surrounding musculature. This diagnosis is often missed or misdiagnosed because popliteal artery entrapment syndrome has a presentation similar to that of exertional compartment syndrome. Popliteal artery entrapment syndrome may result in persistent disability or unnecessary morbidity or prevent athletes' return to sport...
September 21, 2017: Orthopedics
https://www.readbyqxmd.com/read/28934385/hearing-loss-without-overt-metabolic-acidosis-in-atp6v1b1-deficient-mrl-mice-a-new-genetic-model-for-non-syndromic-deafness-with-enlarged-vestibular-aqueducts
#2
Cong Tian, Leona H Gagnon, Chantal Longo-Guess, Ron Korstanje, Susan M Sheehan, Kevin K Ohlemiller, Angela D Schrader, Jaclynn M Lett, Kenneth R Johnson
Mutations of the human ATP6V1B1 gene cause distal renal tubular acidosis (dRTA; OMIM #267300) often associated with sensorineural hearing impairment; however, mice with a knockout mutation of Atp6v1b1 were reported to exhibit a compensated acidosis and normal hearing. We discovered a new spontaneous mutation (vortex, symbol vtx) of Atp6v1b1 in an MRL/MpJ (MRL) colony of mice. In contrast to the reported phenotype of the knockout mouse, which was developed on a primarily C57BL/6 (B6) strain background, MRL-Atp6v1b1vtx/vtx mutant mice exhibit profound hearing impairment, which is associated with enlarged endolymphatic compartments of the inner ear...
October 1, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28927935/different-effect-of-percutaneous-plate-insertion-via-anteromedial-vs-anterolateral-approach-on-intracompartmental-pressure-of-the-leg-a-cadaveric-study
#3
Chavarin Amarase, Wanchat Thimasarn, Saran Tantavisut, Thanasil Huanmanop, Yongsak Wangroongsub, Worawat Limthongkul
BACKGROUND: Currently Minimally Invasive Plate Osteosynthesis (MIPO) technique for tibial shaft fracture management has gained wide attention. However, an increased intracompartmental pressure after the plate insertion may result in postoperative acute compartment syndrome. We reported the difference of immediate effect of percutaneous plate insertion using 2 approaches of MIPO technique on anterior compartment pressure of the legs. MATERIALS AND METHODS: Eight soft cadaveric legs (one female and three males) without previous history of skeletal trauma or surgery were infused with normal saline to create the sustained intracompartmental pressure of 20mm Hg in all four compartments...
September 6, 2017: Injury
https://www.readbyqxmd.com/read/28925916/necrotizing-pancreatitis-resulting-in-abdominal-compartment-syndrome-a-case-report-from-a-remote-northern-hospital-and-literature-review
#4
Dominika Jegen, Ren Ee Choo
No abstract text is available yet for this article.
2017: Canadian Journal of Rural Medicine
https://www.readbyqxmd.com/read/28922957/spinal-meninges-and-their-role-in-spinal-cord-injury-a-neuroanatomical-review
#5
Lukas Grassner, Andreas Grillhösl, Christoph Griessenauer, Claudius Thomé, Volker Bühren, Martin Strowitzki, Peter Winkler
Current recommendations support early surgical decompression and blood pressure augmentation after traumatic spinal cord injury (SCI). Elevated intraspinal pressure (ISP), however, has probably been underestimated in the pathophysiology of SCI. Recent studies provide some evidence that ISP measurements and durotomy may be beneficial for individuals suffering from SCI. Compression of the spinal cord against the meninges in SCI patients causes a 'compartment-like' syndrome. In such cases, intentional durotomy with augmentative duroplasty to reduce ISP and improve spinal cord perfusion pressure may be indicated...
September 19, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28922702/impending-abdominal-compartment-syndrome-from-a-giant-ovarian-cyst-torsion
#6
Tae-Jun Kim, Yu-Ting Yeh, Karishma Zobair
No abstract text is available yet for this article.
September 18, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28919595/a-case-of-hepatorenal-syndrome-and-abdominal-compartment-syndrome-with-high-renal-congestion
#7
Hiroteru Kamimura, Takayuki Watanabe, Tomoyuki Sugano, Nao Nakajima, Junji Yokoyama, Kenya Kamimura, Atsunori Tsuchiya, Masaaki Takamura, Hirokazu Kawai, Takashi Kato, Gen Watanabe, Satoshi Yamagiwa, Shuji Terai
BACKGROUND Hepatorenal syndrome (HRS) is a reversible renal impairment that occurs in patients with acute liver failure and advanced liver cirrhosis. HRS is due to a renal vasoconstriction that results from extreme vasodilatation. It is therefore a functional disorder, not associated with structural kidney damage. On the other hand, end-stage liver diseases are often complicated by massive ascites. Massive ascites may cause abdominal compartment syndrome (ACS), which includes impairment of renal blood flow, but there are no reports indicating that kidney lesions caused by ACS may pathologically contribute to end-stage liver diseases...
September 18, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28919457/patterns-of-botulinum-toxin-treatment-for-spasticity-and-bleeding-complications-in-patients-with-thrombotic-risk
#8
Chetan P Phadke, Vivekanand Thanikachalam, Farooq Ismail, Chris Boulias
The purpose of this study was to assess the prevalence of compartment syndrome or major bleeding episodes and compare compartment syndrome, patient and intervention characteristics in 110 patients with stroke (treated with Warfarin, new oral anticoagulants, antiplatelet, or no anticoagulants) treated for spasticity in deep leg compartment muscles with botulinum toxin injections [onabotulinumtoxinA (n = 77); incobotulinumtoxinA (n = 33)]. We reviewed 674 injection cycles (range 1-25 cycles per patient) and found no cases of compartment syndrome in any patient groups...
September 15, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/28916127/open-thoracic-and-thoraco-abdominal-aortic-repair-in-patients-with-connective-tissue-disease
#9
Paula R Keschenau, Drosos Kotelis, Jeroen Bisschop, Mohammad E Barbati, Jochen Grommes, Barend Mees, Alexander Gombert, Arnoud G Peppelenbosch, Geert Willem H Schurink, Johannes Kalder, Michael J Jacobs
OBJECTIVE/BACKGROUND: The aim is to present current results of open complex aortic repair in patients with connective tissue disease (CTD). METHODS: This was a retrospective cross-border, single centre study. From February 2000 to April 2016 72 aortic operations were performed on 65 patients with CTD (41 male, median age 41 years [range 19-70 years]). Fifty-six patients (86%) underwent at least one previous aortic repair (71 open, four endovascular), including 33 patients (51%) operated before at the site of the procedure reported here...
September 12, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28913973/bone-marrow-stem-cells-do-not-contribute-to-endometrial-cell-lineages-in-chimeric-mouse-models
#10
Yih Rue Ong, Fiona L Cousins, Xiaoqing Yang, Ahmed Aedh A Al Mushafi, David T Breault, Caroline E Gargett, James A Deane
Studies from five independent laboratories conclude that bone marrow stem cells transdifferentiate into endometrial stroma, epithelium and endothelium. We investigated the nature of bone marrow-derived cells in the mouse endometrium by reconstituting irradiated wild type recipients with bone marrow containing transgenic mTert-GFP or chicken β-actin-GFP reporters. mTert-GFP is a telomerase marker identifying hematopoietic stem cells and subpopulations of epithelial, endothelial and immune cells in the endometrium...
September 15, 2017: Stem Cells
https://www.readbyqxmd.com/read/28913787/mortality-rates-and-risk-factors-for-emergent-open-repair-of-abdominal-aortic-aneurysms-in-the-endovascular-era
#11
Felice Pecoraro, Steffen Gloekler, Caecilia E Mader, Malgorzata Roos, Lyubov Chaykovska, Frank J Veith, Neal S Cayne, Nicola Mangialardi, Thomas Neff, Mario Lachat
The background of this paper is to report the mortality at 30 and 90 days and at mean follow-up after open abdominal aortic aneurysms (AAA) emergent repair and to identify predictive risk factors for 30- and 90-day mortality. Between 1997 and 2002, 104 patients underwent emergent AAA open surgery. Symptomatic and ruptured AAAs were observed, respectively, in 21 and 79% of cases. Mean patient age was 70 (SD 9.2) years. Mean aneurysm maximal diameter was 7.4 (SD 1.6) cm. Primary endpoints were 30- and 90-day mortality...
September 14, 2017: Updates in Surgery
https://www.readbyqxmd.com/read/28905040/postrenal-acute-kidney-injury-and-abdominal-compartment-syndrome-associated-with-bladder-pressure-type-iii-rectus-sheath-hematoma
#12
Emre Bozdağ, Ebubekir Gündeş, Ulaş Aday, Hüseyin Çiyiltepe, Durmuş Ali Çetin, Selçuk Gülmez, Aziz Serkan Senger
No abstract text is available yet for this article.
2017: Arch Med Sci Atheroscler Dis
https://www.readbyqxmd.com/read/28894286/intermittent-hypoxia-induced-insulin-resistance-is-associated-with-alterations-in-white-fat-distribution
#13
Laureline Poulain, Hervé Mathieu, Amandine Thomas, Anne-Laure Borel, Chantal Remy, Patrick Levy, Claire Arnaud, Maurice Dematteis
Sleep apnea syndrome is characterized by repetitive upper airway collapses during night leading to intermittent hypoxia (IH). The latter is responsible for metabolic disturbances that rely, at least in part, on abdominal white fat inflammation. Besides qualitative alterations, we hypothesized that IH could also modify body fat distribution, a key factor for metabolic complications. C57BL6 mice exposed to IH (21-5% FiO2, 60 s cycle, 8 h/day) or air for 6 weeks were investigated for topographic fat alterations (whole-body MRI)...
September 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28890727/popliteal-artery-entrapment-or-chronic-exertional-compartment-syndrome
#14
Christopher Gaunder, Brandon McKinney, Jessica Rivera
Diagnosis of lower limb pain in an athlete can be a challenging task due to the variety of potential etiologies and ambiguity of presenting symptoms. Five of the most commonly encountered causes of limb pain in athletes are chronic exertional compartment syndrome (CECS), medial tibial stress syndrome (MTSS), tibial stress fractures, soleal sling syndrome, and popliteal artery entrapment syndrome (PAES). Of these, the least frequent but potentially most serious of the pathologies is PAES. With an incidence of less than 1% seen in living subject studies, the condition is rare...
2017: Case Reports in Medicine
https://www.readbyqxmd.com/read/28880010/chronic-pancreatitis
#15
REVIEW
Jorg Kleeff, David C Whitcomb, Tooru Shimosegawa, Irene Esposito, Markus M Lerch, Thomas Gress, Julia Mayerle, Asbjørn Mohr Drewes, Vinciane Rebours, Fatih Akisik, J Enrique Domínguez Muñoz, John P Neoptolemos
Chronic pancreatitis is defined as a pathological fibro-inflammatory syndrome of the pancreas in individuals with genetic, environmental and/or other risk factors who develop persistent pathological responses to parenchymal injury or stress. Potential causes can include toxic factors (such as alcohol or smoking), metabolic abnormalities, idiopathic mechanisms, genetics, autoimmune responses and obstructive mechanisms. The pathophysiology of chronic pancreatitis is fairly complex and includes acinar cell injury, acinar stress responses, duct dysfunction, persistent or altered inflammation, and/or neuro-immune crosstalk, but these mechanisms are not completely understood...
September 7, 2017: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/28878215/respiratory-oscillations-in-alveolar-oxygen-tension-measured-in-arterial-blood
#16
Federico Formenti, Nikhil Bommakanti, Rongsheng Chen, John N Cronin, Hanne McPeak, Delphine Holopherne-Doran, Goran Hedenstierna, Clive E W Hahn, Anders Larsson, Andrew D Farmery
Arterial oxygen partial pressure can increase during inspiration and decrease during expiration in the presence of a variable shunt fraction, such as with cyclical atelectasis, but it is generally presumed to remain constant within a respiratory cycle in the healthy lung. We measured arterial oxygen partial pressure continuously with a fast intra-vascular sensor in the carotid artery of anaesthetized, mechanically ventilated pigs, without lung injury. Here we demonstrate that arterial oxygen partial pressure shows respiratory oscillations in the uninjured pig lung, in the absence of cyclical atelectasis (as determined with dynamic computed tomography), with oscillation amplitudes that exceeded 50 mmHg, depending on the conditions of mechanical ventilation...
September 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28875127/synthesis-of-evidence-for-the-treatment-of-intersection-syndrome
#17
REVIEW
Konstantine Balakatounis, Antonios G Angoules, Nikolaos A Angoules, Kalomoira Panagiotopoulou
Intersection syndrome is a rare sports overuse injury occurring through friction at the intersection of the first and second compartment of the forearm. Differential diagnosis must be carefully made, especially from De Quervain tendonsynovitis. Clinical examination provides with the necessary information for diagnosis, still magnetic resonance imaging scans and ultrasonography may assist in diagnosis. Treatment consists mainly of rest, use of a thumb spica splint, analgetic and oral nonsteroidal anti-inflammatory drugs and after 2-3 wk progressive stretching and muscle strengthening...
August 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28874445/ifn-%C3%AE-mediates-experimental-cerebral-malaria-by-signalling-within-both-the-hematopoietic-and-non-hematopoietic-compartments
#18
Ana Villegas-Mendez, Patrick Strangward, Tovah N Shaw, Ivana Rajkovic, Vinko Tosevski, Ruth Forman, Werner Muller, Kevin N Couper
Experimental cerebral malaria (ECM) is an IFN-γ dependent syndrome. However, whether IFN-γ promotes ECM through direct and synergistic targeting of multiple cell populations or whether it causes ECM through acting primarily on a specific responsive cell type, is currently unknown. Here, using a panel of cell and compartment-specific IFN- γR2 deficient mice, we show that IFN-γ causes ECM by signalling within both the hematopoietic and non-haematopoietic compartments. Mechanistically, hematopoietic and non-haematopoietic compartment-specific IFN-γR signalling exerts additive effects in orchestrating intracerebral inflammation leading to ECM development...
September 5, 2017: Infection and Immunity
https://www.readbyqxmd.com/read/28872527/muscle-microvascular-blood-flow-oxygenation-ph-and-perfusion-pressure-decrease-in-simulated-acute-compartment-syndrome
#19
Sravya T Challa, Alan R Hargens, Amarachi Uzosike, Brandon R Macias
BACKGROUND: The current gold standard for diagnosing acute compartment syndrome (ACS) is an assessment of clinical signs, invasive measurement of intramuscular pressure (IMP), and measurement of local perfusion pressure. However, IMP measurements have several shortcomings, including pain, risk of infection, risk of technique error, plugging of the catheter tip, lack of consensus on the diagnostic pressure threshold, and lack of specificity and sensitivity. The objective of this study was to evaluate muscle hemodynamics, oxygenation, and pH as diagnostic parameters in a human model of ACS...
September 6, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28869903/biomechanical-differences-between-cases-with-suspected-chronic-exertional-compartment-syndrome-and-asymptomatic-controls-during-running
#20
Andrew Roberts, David Roscoe, David Hulse, Alexander N Bennett, Sharon Dixon
Chronic exertional compartment syndrome (CECS) has been hypothesised, following clinical observations, to be the result of abnormal biomechanics predominantly at the ankle. Treatment of CECS through running re-education to correct these abnormalities has been reported to improve symptoms. However no primary research has been carried out to investigate the movement patterns of those with CECS. This study aimed to compare the running kinematics and muscle activity of cases with CECS and asymptomatic controls...
August 30, 2017: Gait & Posture
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