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catheter bacteremia

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https://www.readbyqxmd.com/read/28525671/infection-in-critically-ill-pediatric-patients-on-continuous-renal-replacement-therapy
#1
Maria J Santiago, Jesús López-Herce, Eva Vierge, Ana Castillo, Amaya Bustinza, Jose M Bellón, Amelia Sánchez, Sarah Fernández
INTRODUCTION: Continuous renal replacement therapies (CRRT) are frequently used in critically ill children and may increase the risk of infection. However, the incidence, characteristics and prognosis of infection in critically ill children on CRRT have not been studied. METHODS: Data from a prospective, single-center register of critically ill children treated with CRRT was analyzed. RESULTS: 55 children (40% under 1 year of age) were treated with CRRT between June 2008 and January 2012; 43 patients (78...
May 18, 2017: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/28525644/risk-factors-and-clinical-outcomes-of-breakthrough-yeast-bloodstream-infections-in-patients-with-hematological-malignancies-in-the-era-of-newer-antifungal-agents
#2
Si-Hyun Kim, Jae-Ki Choi, Sung-Yeon Cho, Hyo-Jin Lee, Sun Hee Park, Su-Mi Choi, Dong-Gun Lee, Jung-Hyun Choi, Jin-Hong Yoo, Jong-Wook Lee
Although yeast bloodstream infections (BSIs) are increasingly being reported in patients with hematological malignancies undergoing antifungal therapy, clinical information regarding breakthrough infections is scarce. The aim of this study was to determine the risk factors for and clinical outcomes of breakthrough yeast BSIs in patients with hematological malignancies in the era of newer antifungal agents. Between 2011 and 2014, all consecutive patients with hematological malignancies who developed yeast BSIs were included in a case-control study wherein breakthrough infections (cases) and de novo infections (controls) were compared...
May 19, 2017: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/28485119/case-of-mycobacterium-mucogenicum-in-home-hemodialysis-patient
#3
Miten J Dhruve, Paul E Bunce, Celine D'Gama, Christopher T Chan
We present a case of a patient on home hemodialysis who developed Mycobacterium mucogenicum bacteremia. While infections with this particular organism are rare, disseminated infections have been reported and have been associated with significant morbidity and mortality. Diagnosis required appropriate cultures, understanding of natural habitat of organism and complete environmental analysis including blood, dialysis sample port, reverse osmosis and incoming water supply cultures. The patient was treated successfully with systemic antibiotics, removal of central venous catheter, patient education and complete exchange of the hemodialysis circuit...
May 9, 2017: Hemodialysis International
https://www.readbyqxmd.com/read/28477236/pathogen-related-factors-affecting-outcome-of-catheter-related-bacteremia-due-to-methicillin-susceptible-staphylococcus-aureus-in-a-spanish-multicenter-study
#4
R San-Juan, D Pérez-Montarelo, E Viedma, A Lalueza, J Fortún, E Loza, M Pujol, C Ardanuy, I Morales, M de Cueto, E Resino-Foz, M A Morales-Cartagena, M Fernández-Ruiz, A Rico, M P Romero, M Fernández de Mera, F López-Medrano, M Á Orellana, J M Aguado, F Chaves
Even with appropriate clinical management, complicated methicillin-susceptible Staphylococcus aureus (MSSA) catheter-related bacteremia (CRB) is frequent. We investigated the influence of molecular characteristics of MSSA strains on the risk of complicated bacteremia (CB) in MSSA-CRB. A multicenter prospective study was conducted in Spain between 2011 and 2014 on MSSA-CRB. Optimized protocol-guided clinical management was required. CB included endocarditis, septic thrombophlebitis, persistent bacteremia and/or end-organ hematogenous spread...
May 5, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28448786/microbiological-features-and-clinical-impact-of-the-type-vi-secretion-system-t6ss-in-acinetobacter-baumannii-isolates-causing-bacteremia
#5
Jungok Kim, Ji-Young Lee, Haejeong Lee, Ji Young Choi, Dae Hun Kim, Yu Mi Wi, Kyong Ran Peck, Kwan Soo Ko
We investigated the genetic background and microbiological features of T6SS-positive Acinetobacter baumannii isolates and clinical impact of the T6SS in patients with A. baumannii bacteremia. One hundred and sixty-two A. baumannii isolates from patients with bacteremia in two tertiary-care hospitals in Korea were included in this study. Approximately one-third (51/162, 31.5%) of the A. baumannii clinical isolates possessed the hcp gene, and the hcp-positive isolates were found in several genotypes in multilocus sequence typing...
April 27, 2017: Virulence
https://www.readbyqxmd.com/read/28438461/bacteremia-caused-by-the-photosynthetic-environmental-bacterium-rhodopseudomonas
#6
Stephanie L Mitchell, Emily A Blumberg, Paul H Edelstein
We report a case of persistent Rhodopseudomonas bacteremia in a patient two months after an allogeneic bone marrow transplant for acute myeloid leukemia. The bacteremia persisted until IV catheter removal. To our knowledge, this is the first report of Rhodopseudomonas causing infection in humans.
April 21, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/28435789/aerococcus-urinae-an-emerging-cause-of-urinary-tract-infection-in-older-adults-with-multimorbidity-and-urologic-cancer
#7
Andrew Higgins, Tullika Garg
Aerococcus urinae is a rare organism isolated from urine cultures. We present a case of an 80 year-old male with bladder cancer and multimorbidity who developed A. urinae infection. A. urinae may cause simple and complicated UTIs, bacteremia, and endocarditis in older adults with multimorbidity, chronic urinary retention, or indwelling catheters. A. urinae treatment should employ penicillin, amoxicillin, and nitrofurantoin. Due to increasing antibiotic resistance, urine culture should include antibiotic susceptibility testing...
July 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28429519/the-incidence-and-costs-of-bacteremia-due-to-lack-of-gentamicin-lock-solutions-for-dialysis-catheters
#8
Tze Liang Goh, Jason Wei, David Semple, John Collins
The use of antibiotic lock solutions as prophylaxis for catheter-associated blood stream infection (CRBSI) has been shown to be effective in previous randomized controlled trials. However, the cost-effectiveness of this approach had not been studied. In 2012, the routine gentamicin-heparin lock solution used in Auckland City Hospital was withdrawn from the market, leading to a change to heparin-only lock. This was then replaced with gentamicin-citrate lock in 2014. This situation allowed review of the CRBSI rate and financial impact of different catheter lock solutions...
June 2017: Nephrology
https://www.readbyqxmd.com/read/28419010/extending-short-peripheral-catheter-dwell-time-a-best-practice-discussion
#9
Brenda Ansel, Michelle Boyce, Jennifer L Embree
Complications involving short peripheral catheters (SPCs) can significantly affect health care costs, patient quality of life, morbidity, mortality, and treatment expense, especially when the hospital stay is lengthened. This article examines the relationship between SPC dwell time and the incidence of phlebitis and potential bacteremia. The literature is replete with most studies supporting SPCs remaining in situ until a clinical reason warrants catheter removal. Removing and not routinely restarting unneccessary intravenous catheters can help prevent catheter-related infections and other vascular complications and reduce cost...
May 2017: Journal of Infusion Nursing: the Official Publication of the Infusion Nurses Society
https://www.readbyqxmd.com/read/28408667/draft-genome-sequence-of-roseomonas-mucosa-strain-au37-isolated-from-a-peripheral-intravenous-catheter
#10
Md Abu Choudhury, Alexander M Wailan, Hanna E Sidjabat, Li Zhang, Nicole Marsh, Claire M Rickard, Mark R Davies, David J McMillan
Roseomonas mucosa is an opportunistic pathogen that causes infections in humans and is often associated with vascular catheter-related bacteremia. Here, we report the draft genome sequence of Roseomonas mucosa strain AU37, isolated from a peripheral intravenous catheter tip.
April 13, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28381743/clinical-characteristics-of-methicillin-resistant-coagulase-negative-staphylococcal-bacteremia-in-a-tertiary-hospital
#11
Koichi Yamada, Hiroki Namikawa, Hiroki Fujimoto, Kiyotaka Nakaie, Etsuko Takizawa, Yasuyo Okada, Akiko Fujita, Hiroyoshi Kawaguchi, Yasutaka Nakamura, Junko Abe, Yukihiro Kaneko, Hiroshi Kakeya
Objective Coagulase-negative staphylococci are among the most frequently isolated microorganisms in blood cultures. The aim of this study was to assess [1] the clinical characteristics of methicillin-resistant, coagulase-negative staphylococci bacteremia and [2] the susceptibility of the isolated bacteria to glycopeptides. Methods We retrospectively reviewed the medical records of 70 patients from whom methicillin-resistant coagulase-negative staphylococci had been isolated at Osaka City University Hospital between January 2010 and December 2013...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28345481/cost-effectiveness-analysis-of-implementing-an-antimicrobial-stewardship-program-in-critical-care-units
#12
Jesus Ruiz-Ramos, Juan Frasquet, Eva Romá, Jose Luis Poveda-Andres, Miguel Salavert-Leti, Alvaro Castellanos, Paula Ramirez
AIMS: To evaluate the cost-effectiveness of antimicrobial stewardship (AS) program implementation focused on critical care units based on assumptions for the Spanish setting. MATERIALS AND METHODS: A decision model comparing costs and outcomes of sepsis, community-acquired pneumonia, and nosocomial infections (including catheter-related bacteremia, urinary tract infection, and ventilator-associated pneumonia) in critical care units with or without an AS was designed...
April 13, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28335676/physiopathological-approach-to-infective-endocarditis-in-chronic-hemodialysis-patients-left-heart-versus-right-heart-involvement
#13
Yassamine Bentata
Infectious endocarditis (IE), a complication that is both cardiac and infectious, occurs frequently and is associated with a heavy burden of morbidity and mortality in chronic hemodialysis patients (CHD). About 2-6% of chronic hemodialysis patients develop IE and the incidence is 50-60 times higher among CHD patients than in the general population. The left heart is the most frequent location of IE in CHD and the different published series report a prevalence of left valve involvement varying from 80% to 100%...
November 2017: Renal Failure
https://www.readbyqxmd.com/read/28279491/proposal-for-shorter-antibiotic-therapies
#14
C Wintenberger, B Guery, E Bonnet, B Castan, R Cohen, S Diamantis, P Lesprit, L Maulin, Y Péan, E Peju, L Piroth, J P Stahl, C Strady, E Varon, F Vuotto, R Gauzit
OBJECTIVES: Reducing antibiotic consumption has now become a major public health priority. Reducing treatment duration is one of the means to achieve this objective. Guidelines on the therapeutic management of the most frequent infections recommend ranges of treatment duration in the ratio of one to two. The Recommendation Group of the French Infectious Diseases Society (SPILF) was asked to collect literature data to then recommend the shortest treatment durations possible for various infections...
March 6, 2017: Médecine et Maladies Infectieuses
https://www.readbyqxmd.com/read/28276799/comparison-of-outcome-and-clinical-characteristics-of-bacteremia-caused-by-methicillin-resistant-penicillin-resistant-and-penicillin-susceptible-staphylococcus-aureus-strains
#15
COMPARATIVE STUDY
Elina Jokinen, Janne Laine, Reetta Huttunen, Pekka Rahikka, Heini Huhtala, Risto Vuento, Jaana Vuopio, Jaana Syrjänen
BACKGROUND: The aim of this study was to assess the association of methicillin resistance and penicillinase production with clinical characteristics and outcome of Staphylococcus aureus bacteremia. METHODS: For 126 patients with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia, 378 age- and gender-matched controls with methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia were selected. Of controls, 126 had bacteremia caused by penicillin-susceptible strains (PSSA) and 252 by penicillinase-producing strains (PRSA)...
July 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28259730/incidence-of-central-venous-catheter-hub-contamination
#16
Julie L Holroyd, Terrie Vasilopoulos, Mark J Rice, Kenneth H Rand, Brenda G Fahy
PURPOSE: To investigate microorganisms causing central venous catheter contamination and how this contamination differs across different catheter metrics. MATERIALS AND METHODS: After obtaining IRB approval and informed consent, 830 cultures were prospectively obtained from 45 ICU patients with central venous catheter or peripherally inserted central catheter. Bacterial colonies were identified by mass spectrometry. RESULTS: Bacterial contamination of central catheter hubs occurred 44% of the time in this study in the ICU setting...
June 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28254252/improvement-in-the-diagnosis-of-catheter-related-bloodstream-infections-in-a-tertiary-cancer-center
#17
Patrick Chaftari, Anne-Marie Chaftari, Javier Adachi, Ray Hachem, Sammy Raad, Elizabeth Natividad, Nora Oliver, Bena Ellickalputhenpura, Ying Jiang, Jeffrey Tarrand, Issam Raad
BACKGROUND: Identifying a central venous catheter (CVC) as the source of bacteremia requires drawing simultaneous blood cultures (BCs) from the CVC and peripheral site and correct labeling of the BC source. In our emergency center (EC), 52% of BCs collected from febrile cancer patients lacked source information, making the diagnosis and management of catheter-related bloodstream infections (CRBSIs) challenging. METHODS: Between January 2015 and June 2015, we conducted a quality improvement project in our EC aiming to increase the occurrence of simultaneous BC drawing with accurate source labeling by 10%...
March 1, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28244579/prevention-of-healthcare-associated-infections-a-descriptive-study
#18
R Accardi, S Castaldi, A Marzullo, S Ronchi, D Laquintana, M Lusignani
BACKGROUND: This study aims to verify whether there are, and to which degree, knowledge and adherence to guidelines on the prevention and control of healthcare associated infections by nursing staff. Study design. A descriptive study was conducted on a sample of nurses in the areas of medicine, surgery, and its own specialties of the Istituto di Ricovero e Cura a Carattere Scientifico Ca' Granda Ospedale Maggiore Policlinico in Milan from 1st December 2015 to 29th February 2016. METHODS: The knowledge of the nursing staff have been investigated through the use of questionnaires with anonymous self-reporting method; inspections in the wards using observational grids were carried out in order to verify adherence to best-practice principles...
March 2017: Annali di Igiene: Medicina Preventiva e di Comunità
https://www.readbyqxmd.com/read/28243995/septic-pulmonary-emboli-detected-by-18-f-fdg-pet-ct-in-children-with-s-aureus-catheter-related-bacteremia
#19
A Méndez-Echevarria, M Coronado-Poggio, F Baquero-Artigao, T Del Rosal, S Rodado-Marina, C Calvo, L Domínguez-Gadea
PURPOSE: The role of (18)F-fluorodeoxyglucose positron emission tomography-computed tomography ((18)F-FDG PET/CT) in the diagnosis of metastatic infectious foci in children with catheter-related blood stream infection has been hardly studied, although some authors have reported it benefit in the screening of metastatic foci in adult population. Septic pulmonary emboli are among the most difficult to identify, because many cases do not present pulmonary complaints or abnormal chest radiography...
February 27, 2017: Infection
https://www.readbyqxmd.com/read/28236919/a-randomized-controlled-trial-and-cost-effectiveness-analysis-of-early-cannulation-arteriovenous-grafts-versus-tunneled-central-venous-catheters-in-patients-requiring-urgent-vascular-access-for-hemodialysis
#20
RANDOMIZED CONTROLLED TRIAL
Emma Aitken, Peter Thomson, Leigh Bainbridge, Ram Kasthuri, Belinda Mohr, David Kingsmore
OBJECTIVE: Early cannulation arteriovenous grafts (ecAVGs) are proposed as an alternative to tunneled central venous catheters (TCVCs) in patients requiring immediate vascular access for hemodialysis (HD). We compared bacteremia rates in patients treated with ecAVG and TCVC. METHODS: The study randomized 121 adult patients requiring urgent vascular access for HD in a 1:1 fashion to receive an ecAVG with or without (+/-) an arteriovenous fistula (AVF; n = 60) or TCVC+/-AVF (n = 61)...
March 2017: Journal of Vascular Surgery
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