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spasticity botulinum toxin

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https://www.readbyqxmd.com/read/27882910/does-nintendo-wii-balance-board-improve-standing-balance-a-randomised-controlled-trial-in-children-with-cerebral-palsy
#1
Valeska Gatica-Rojas, Guillermo Méndez-Rebolledo, Eduardo Guzman-Muñoz, Alex Soto-Poblete, Ricardo Cartes-Velásquez, Edith Elgueta-Cancino, Eduardo Cofré Lizama
BACKGROUND: Evidence on the effect of systemic exercise programs to improve the standing balance with the Nintendo Wii system is very limited and its post- treatment effectiveness is unknown in cerebral palsy (CP) patients. AIM: Primary aim was to compare the effect of Nintendo Wii balance board (Wii- therapy) and standard physiotherapy (SPT), on the performance of standing balance in children and adolescents with CP. Secondary aim was to determine the post-treatment effectiveness of Wii-therapy and SPT...
November 24, 2016: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27871449/botulinum-toxin-as-early-intervention-for-spasticity-after-stroke-or-non-progressive-brain-lesion-a-meta-analysis
#2
Raymond L Rosales, Fran Efendy, Ericka Sa Teleg, Mary Md Delos Santos, Mary Ce Rosales, Marc Ostrea, Michelle J Tanglao, Arlene R Ng
Spasticity is a functionally limiting disorder that commonly occurs following stroke or severe brain injury, and may lead to disability and pain. In tandem with neurorehabilitation, botulinum toxin type A (BoNT-A) is the recommended first-line treatment for spasticity and, to date, the majority of trials have reported BoNT-A use in patients >6months after ictus. The present meta-analysis aimed to evaluate the effects of early BoNT-A injection for post-stroke spasticity on improvements in hypertonicity, disability, function and associated pain...
December 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27852706/efficacy-of-two-injection-site-localisation-techniques-for-botulinum-toxin-injections-a-single-blind-crossover-randomised-trial-protocol-among-adults-with-hemiplegia-due-to-stroke
#3
Claire Morel, Isabelle Hauret, Nicolas Andant, Armand Bonnin, Bruno Pereira, Emmanuel Coudeyre
INTRODUCTION: Botulinum toxin injections are an effective treatment for limb spasticity following stroke. Different tracking techniques are used for this purpose: palpation, electrostimulation, electromyography and ultrasound. Yet very few studies have compared these different techniques, and none has successfully proved the superior efficacy of ultrasound-guided injections compared to another tracking method. The primary objective of our study was therefore to compare the efficacy of botulinum toxin injections depending on the tracking technique used: ultrasound versus electrostimulation...
November 15, 2016: BMJ Open
https://www.readbyqxmd.com/read/27834471/efficacy-and-safety-of-botulinum-toxin-type-a-for-upper-limb-spasticity-after-stroke-or-traumatic-brain-injury-a-systematic-review-with-meta-analysis-and-trial-sequential-analysis
#4
Yan Dong, Tao Wu, Xiaohua Hu, Tong Wang
INTRODUCTION: Muscle spasticity is a positive symptom after stroke and traumatic brain injury. Botulinum Toxin type A injection is widely used for treating post stroke and traumatic brain injury spasticity. This study aimed to evaluate efficacy and safety of Botulinum Toxin type A for upper limb spasticity after stroke and traumatic brain injury and investigate reliability and conclusiveness of available evidence for Botulinum Toxin type A intervention. EVIDENCE ACQUISITION: We searched electronic databases from inception to September 10 of 2016...
November 11, 2016: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27787630/botulinum-toxin-therapy-for-treatment-of-spasticity-in-multiple-sclerosis-review-and-recommendations-of-the-iab-interdisciplinary-working-group-for-movement-disorders-task-force
#5
Dirk Dressler, Roongroj Bhidayasiri, Saeed Bohlega, Abderrahmane Chahidi, Tae Mo Chung, Markus Ebke, L Jorge Jacinto, Ryuji Kaji, Serdar Koçer, Petr Kanovsky, Federico Micheli, Olga Orlova, Sebastian Paus, Zvezdan Pirtosek, Maja Relja, Raymond L Rosales, José Alberto Sagástegui-Rodríguez, Paul W Schoenle, Gholam Ali Shahidi, Sofia Timerbaeva, Uwe Walter, Fereshte Adib Saberi
Botulinum toxin (BT) therapy is an established treatment of spasticity due to stroke. For multiple sclerosis (MS) spasticity this is not the case. IAB-Interdisciplinary Working Group for Movement Disorders formed a task force to explore the use of BT therapy for treatment of MS spasticity. A formalised PubMed literature search produced 55 publications (3 randomised controlled trials, 3 interventional studies, 11 observational studies, 2 case studies, 35 reviews, 1 guideline) all unanimously favouring the use of BT therapy for MS spasticity...
October 27, 2016: Journal of Neurology
https://www.readbyqxmd.com/read/27769363/should-ultrasound-be-used-routinely-to-guide-botulinum-toxin-injections-for-spasticity
#6
John McGuire, Kelly Heath, Michael W O'Dell
No abstract text is available yet for this article.
October 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27764971/effect-of-electrical-stimulation-as-an-adjunct-to-botulinum-toxin-type-a-in-the-treatment-of-adult-spasticity-a-systematic-review
#7
Domenico Intiso, Andrea Santamato, Filomena Di Rienzo
OBJECTIVE: To investigate whether electrical stimulation (ES) as an adjunct to BTX-A boosts botulinum activity and whether the combined therapeutic procedure is more effective than BTX-A alone in reducing spasticity in adult subjects. DATA SOURCES: A search was conducted in PubMed, EMBASE, Cochrane Central Register, and CINAHL from January 1966 to January 2016. STUDY SELECTION: Only randomized controlled studies (RCT) involving the combination of BTX-A and ES were considered...
October 21, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27744462/effects-of-botulinum-toxin-serotype-a-on-sleep-problems-in-children-with-cerebral-palsy-and-on-mothers-sleep-quality-and-depression
#8
Vildan Binay Safer, Sibel Ozbudak Demir, Esma Ozkan, Fulya Demircioglu Guneri
OBJECTIVE: To evaluate botulinum toxin serotype A (BoNT-A) effects on sleep problems in children with cerebral palsy (CP) and on mothers` sleep quality and depression at multiple time points. METHODS: This is a single center, cross sectional, and observational study was conducted to assess children with CP who were admitted. We recruited children with CP who were admitted to Ministry of Health Physical Medicine and Rehabilitation Training and Research Hospital, Ankara, Turkey between September 2012 and April 2014 for the BoNT-A injection for lower limb spasticity...
October 2016: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
https://www.readbyqxmd.com/read/27711973/pharmacological-interventions-other-than-botulinum-toxin-for-spasticity-after-stroke
#9
REVIEW
Cameron Lindsay, Aphrodite Kouzouna, Christopher Simcox, Anand D Pandyan
BACKGROUND: The long-term risk of stroke increases with age, and stroke is a common cause of disability in the community. Spasticity is considered a significantly disabling impairment that develops in people who have had a stroke. The burden of care is higher in stroke survivors who have spasticity when compared with stroke survivors without spasticity with regard to treatment costs, quality of life, and caregiver burden. OBJECTIVES: To assess if pharmacological interventions for spasticity are more effective than no intervention, normal practice, or control at improving function following stroke...
October 6, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27699753/-early-pharmacologic-treatment-with-botulinum-toxin-a-in-post-stroke-spasticity-consensus-evidence-based-recommendations
#10
L Lopez de Munain, F J Juan-Garcia, E Duarte, R Martin-Mourelle, S Rodriguez, S Moraleda-Perez
Spasticity is a common complication that occurs in those patients that have suffered a stroke. To identify those patients at high risk of having post-stroke spasticity and to start treatment at early stages would probably benefit the patient. The key aspects in the early management of post-stroke spasticity were review and the clinical implications and strength of evidences were also considered. The document drafted by the study coordinators was subsequently reviewed and then a validated document was developed...
October 16, 2016: Revista de Neurologia
https://www.readbyqxmd.com/read/27696580/goal-attainment-scaling-in-individuals-with-upper-limb-spasticity-post-stroke
#11
Parvin Eftekhar, George Mochizuki, Tilak Dutta, Denyse Richardson, Dina Brooks
Focusing on rehabilitation goals is an effective approach for improving function in individuals with spasticity after stroke. The objectives of this study were to examine and map goals of post-stroke individuals with spasticity using the Goal Attainment Scale (GAS) and International Classification of Functioning, Disability and Health (ICF), and to evaluate the impact of botulinum toxin A (BoNTA) on occupational performance based on the type of rehabilitation goals. Thirty-one patients were recruited from an outpatient spasticity management clinic...
December 2016: Occupational Therapy International
https://www.readbyqxmd.com/read/27677011/correction-of-hip-internal-rotation-in-walking-cerebral-palsy-adolescent-using-a-soft-tissue-procedure-an-alternative-to-femoral-rotation-osteotomy
#12
Bruno Dohin, Elie Haddad, Hassan Al Khoury Salem, Mohamed Merhez Kilani
OBJECTIVE: Hip internal rotation (HIR) during gait is one of the main functional disorders related to cerebral palsy (CP) in children. Most of the procedures proposed rotational osteotomy of the femur (FRO), (and/or tibia). However, multilevel surgery (SEMLS) including bone procedure, implicates more difficult and longer rehabilitation. When bone deformity is moderate, the authors hypothesized that FRO could be avoided. They developed a soft tissues procedure to improve HIR. The aim of the study was assessment of the procedure...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27677009/functional-evolution-of-children-cerebral-infirm-motors-imc-walking-outside-the-surgery-multi-sites-about-47-cases
#13
Mourad Aderkichi, Fatma Malek
OBJECTIVE: Orthopedic disorders of IMC walking children associated with other disorders of posture and movement get progressively worse with growth causing major deformations that can impede walking from the age of 2 years. The treatments implemented by physiotherapy, botulinum toxin and multi-site surgery significantly improve the functional prognosis of these children. The goal is to evaluate the fate of children who have not benefited from multi-site surgeries that have benefited from physiotherapy, stretching casts botulinum toxin and tenotomy on one or two sites...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27676990/hemiplegic-shoulder-pain-comparison-of-two-sites-of-intramuscular-injections-of-botulinum-toxin-type%C3%A2-a-epautox-study
#14
Sophie Larrazet, Romain Joste, Angélique Stefan, Anne Delaubier, André Gueyraud, Philippe Foucault, Claire Guillou, Thierry Dabbadie
OBJECTIVE: The aim of this study was to compare the analgesic effectiveness of 1 month injection after botulinum toxin in the pectoralis major muscle or subscapularis. MATERIAL/PATIENTS AND METHODS: In this prospective, comparative, randomized, multicenter trial, 21 patients with hemiplegic shoulder pain after a recent stroke (less 6 months) were screened at baseline, then postinjection (Botox(®) 150 units pectoralis major, 100 units subscaplaris) at 1, 4 and 12 weeks...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27676961/physiological-anatomy-of-botulinum-toxin-effect-on-the-spastic-muscle-of-children-with-cerebral-palsy
#15
Claire Mietton, Laurent Schaeffer, Nathalie Streichenberger, Vincent Cunin, Berrouz Kassai, Isabelle Poirot
OBJECTIVE: Botulinum toxin is one of the treatments available to treat spasticity in patients with cerebral palsy (CP) from 2 years of age. The long-term action of the toxin on the neuromuscular junction (NMJ) and muscle structure is still unknown. We formulated the hypothesis that repeated injections of botulinum toxin could modify muscle structure. The main aim of our 3-year monocentric descriptive study is to evaluate the long-term effect of repeated injections of botulinum toxin on the muscle and the neuromuscular junction in patients with CP...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27676911/therapeutic-benefit-of-botulinum-toxin-a-for-the-spasticity-of-the-triceps-surae-in-patients-with-multiple-sclerosis-an-observational-study
#16
Philippe Gallien, Benoit Nicolas, Leblong Emilie, Sabine Petrilli, Sandrine Robineau, Aurelie Durufle, Katell Autret, Tiphaine Berthier, Lucie Chochina, Bastien Fraudet, Corinne Pfeiffer
INTRODUCTION: Few data are available on the use of botulinum toxin for spasticity treatment in multiple sclerosis. In a previous study, we found that one of the main therapeutic goals was the improvement ok walking, in patients suffering from spasticity of the triceps surae. OBJECTIVE: This is a pilot observational study, with the aim to assess the benefit of an injection of 200 UI of incobotulinumtoxin A in multiple sclerosis patients suffering from spasticity du triceps surae...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27676811/assessment-of-pain-during-the-injection-of-the-botulinum-toxin-physical-medicine-and-rehabilitation-experience
#17
Samira Lahrabli, Herman Azanmasso, Fatima Lmidmani, Abdellatif El Fatimi
OBJECTIVE: Intramuscular injection of botulinum toxin can be painful for some patients. This may be due either to a broken skin, stimulation for locating, or injecting the product. The objective of this study was to see the clinical impact of pain on injection. MATERIAL/PATIENTS AND METHODS: Retrospective study of 15 patients (6 M/9 W), average age was 31 years (11-75 years). The patients had spasticity of MS in 40% and a MI spasticity in 60%. The treatment was basic Dysport...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27676801/botulinum-toxin-prescription-in-the-treatment-of-spasticity-in-the-neurological-rehabilitation-service-2012-to-2015%C3%A2-assessment
#18
Aurélie Rochefolle, Emmanuelle Carré, Aurélie Rochefolle, Marie Callies de Sallies, Florence Durand, Catherine Rioufol, Jacques Luaute, Gilles Rode
OBJECTIVE: Botulinum toxins are often prescribed in aftercare and neurological rehabilitation services. In our hospital, they are exponentially used in the treatment of spasticity. The objective of this study is to make an assessment of their use over the period 2012-2015. MATERIAL/PATIENTS AND METHODS: All the botulinum toxin prescriptions are followed by the chemists. A traceability form allows to collect information about the patient, the prescriber, the medicine and its dose, the cost, and the indication...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27676800/plastic-changes-in-spinal-synaptic-transmission-following-botulinum-toxin-a-in-post-stroke-spastic-patients
#19
Marjorie Kerzoncuf, Laurent Bensoussan, Jean Michel Viton, Alain Delarque, Christiane Rossi Durand
OBJECTIVE: The therapeutic effects of intramuscular injections of botulinum toxin-type A on spasticity can be largely explained by its blocking action at the neuromuscular junction. BTx-A is assumed also to have a central action by affecting the functional organization of the CNS. The objective was to assess its action on spinal motor networks by investigating the post-activation depression (post-AD) of the soleus H-reflex in post-stroke patients. Post-AD that is a presynaptic mechanism controlling the synaptic efficacy of Ia-motoneuron transmission is involved in the pathophysiology of spasticity...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27676798/ultrasound-guided-injection-of-botulinum-toxin-in-upper-limb-experience-of-pmr-departement
#20
Samira Lahrabli, Herman Azanmasso, Fatima Lmidmani, Abdellatif El Fatimi
OBJECTIVE: Spasticity of the upper limb is a disabling symptom in patients with vascular hemiplegia, both functionally and orthopedic evolution of these patients. Many treatments exist for spasticity, and botulinum toxin may be an attractive therapeutic alternative, to fight against the often deleterious spasticity. MATERIAL/PATIENTS AND METHODS: We report a retrospective work of 10 spastic patients treated with ultrasound-guided injection of botulinum toxin into the MPR Casablanca service...
September 2016: Annals of Physical and Rehabilitation Medicine
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