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Justin G Julander, Venkatraman Siddharthan, Albert H Park, Elizabeth Preston, Pranav Mathur, Michael Bertolio, Hong Wang, Katherine Zukor, Arnaud J Van Wettere, Donal G Sinex, John D Morrey
Zika virus (ZIKV) can cause various diseases in offspring after congenital infection. The purpose of this study was to identify disease phenotypes in pups exposed to ZIKV in utero. Female interferon-α/β, -γ receptor knockout mice (AG129) were infected intraperitoneally with ZIKV 7.5 days' post coitus (dpc). Viral RNA, antigen and infectious virus were detected in some, but not all, maternal and fetal tissues at various times during gestation. Fetuses of infected dams had significant intrauterine growth restriction (IUGR), which was more pronounced as females neared parturition...
June 20, 2018: Scientific Reports
Joan M Rosell, L Fernando de la Fuente
In this cross-sectional study, prevalence of clinical mastitis (PCM) and farm-specific risk factors were determined on 531 doe rabbit farms in Spain and Portugal, from January 2001 through March 2017. The information was obtained by carrying out 2367 visits and doing physical examinations of 144,455 lactating does, sorted in 2635 cohorts. Overall mean PCM was 4.05% (CI95% [3.87⁻4.22]), (minimum to maximum: 0⁻36.00% PCM). This study suggests that PCM was influenced by the variable number of batches (a batch was a group of does served the same day), per maternity barn ( p < 0...
June 20, 2018: Animals: An Open Access Journal From MDPI
Lihsieh Marrero, Odaléa Maria Brüggemann
OBJECTIVE: To identify the types of institutional violence of childbirth reported by the woman, the birth companion and health professionals. METHOD: Integrative review that analyzed 33 articles in the LILACS, BDENF, INDEXPSI, regional SciELO, Scopus, Web Of Science and PubMed databases. RESULTS: Women were the main violence rapporteur, with predominance of the psychological type. Precarious infrastructure and the imposition of professional decisions were identified by the companion as violence...
May 2018: Revista Brasileira de Enfermagem
Todd R Robeck, Jason L Blum, Karen J Steinman, Jill R Ratner, Don R Bergfelt, Justine K O'Brien
The circulating pattern of immunoreactive relaxin and progestagens based on monthly and gestational stage (early, mid, late) profiles were determined during pregnancies that resulted in live calves (LIVE, n = 30), stillbirths (STILLB, n = 3), abortions (ABORT, n = 5) and presumptive false pregnancies (FALSE, n = 8), and during the follicular (n = 34) and luteal phases (n = 58). Monthly LIVE relaxin concentrations steadily increased during gestation, but values did not significantly exceed those of the luteal phase until 10 months prior to parturition, peaking during the final month at 2,356 ng/ml...
June 15, 2018: General and Comparative Endocrinology
Martina T Ayad, Brandie D Taylor, Ramkumar Menon
PROBLEM: Oxidative stress (OS)-induced, p38 mitogen-activated protein kinase (p38MAPK)-mediated chorioamniotic senescence and inflammation (senescence-associated secretory phenotype [SASP]) are associated with parturition. In response to OS-inducing risk factors, premature senescence contributes to preterm premature rupture of the membranes (pPROM) and spontaneous preterm birth (PTB). We determined the effect of simvastatin, rosuvastatin, and progesterone in downregulating p38MAPK-mediated senescence and SASP...
June 17, 2018: American Journal of Reproductive Immunology: AJRI
L Han, F Batistel, Y Ma, A S M Alharthi, C Parys, J J Loor
The periparturient period is the most critical period during the lactation cycle of dairy cows and is characterized by increased oxidative stress status. The objective of this experiment was to evaluate the effect of supplementing rumen-protected methionine on nuclear factor erythroid 2-like 2 (NFE2L2, formerly NRF2) protein and target gene expression in the mammary gland during the early postpartal period. Multiparous Holstein cows were used in a block design experiment with 30 cows per treatment. Treatments consisting of a basal control diet (control) or the basal diet plus rumen-protected methionine (methionine) were fed from d -28 to 60 relative to parturition...
June 13, 2018: Journal of Dairy Science
Sebastian Ganz, Michael Bülte, Zdzislaw Gajewski, Axel Wehrend
The best studied substances in bovine colostrum are the immunoglobulins. They are absorbed in the small intestine of the neonate by pinocytosis. The Fc-receptor is not highly involved in this process in calves compared to other species. However, this receptor plays a crucial role in the transport of immunoglobulins from the circulation of the dam to the udder and, therefore, into the colostrum. During colostrogenesis, which starts up to 8 weeks prior to parturition, up to 500 g of immunoglobulins are transferred daily by this process...
June 2018: Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere
Stefanie Neuhauser, Patricia Gösele, Johannes Handler
OBJECTIVE: During the peripartal period, interpretation of basic clinical signs may be challenging. In the present study, heart rate (HR), respiratory rate (RR) and body temperature (BT) were evaluated in healthy mares of different breed types and compared to reference values for adult horses from the literature. MATERIAL AND METHODS: During daily physical exams of periparturient mares, the HR, RR and BT were evaluated. Differences according to the horse's size were investigated and in large breeds, the influence of dystocia or retained placenta was analysed...
June 2018: Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere
Katrin Lange, Wolfgang Heuwieser, Carola Fischer-Tenhagen
OBJECTIVE: The aim of this study was to evaluate the influence of Denaverine hydrochloride (DNH) in heifers on calf vitality. MATERIAL AND METHODS: A total of 83 calvings with 38 female and 45 male calves were included in the study. Thirty minutes after onset of stage 2 of calving, 400 mg DNH or placebo (0.9% NaCl) were administered subcutaneously. If the calving procedure was not completed after 60 minutes, an extraction was conducted and pulling force was measured by using a digital force gauge...
June 2018: Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere
Daniela Klaus-Halla, Bettina Mair, Carola Sauter-Louis, Holm Zerbe
OBJECTIVE: In cows with uterine torsion, clinical parameters and different treatments were evaluated with regards to their success. The aim of the study was to investigate important factors for diagnosis and prognosis of uterine torsion and their consequences for treatment decisions. MATERIAL AND METHODS: The study presents 114 cases of uterine torsion documented under field conditions. The cows were examined before retorsion of the uterus and immediately post partum...
June 2018: Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere
María Alejandra Ortega Barco, Lucy Muñoz de Rodríguez
OBJECTIVES: This work sought to compare the evaluation of the nursing care provided during the parturition process in the intervention group based on Swanson's theory of caring versus that of the control group that received conventional care. METHODS: Preventive-type controlled clinical trial conducted in a tier II hospital in San Gil, Santander (Colombia). During the parturition process, the intervention group received care based on Swanson's theory of caring (n=20) and the control group received conventional care (n=23)...
February 2018: Investigación y Educación en Enfermería
Cristina María Mejía Merino, Lida Faneyra Zapata, Diana Patricia Molina Berrio, Juan David Arango Urrea
OBJECTIVES: This work sought to describe the meanings constructed in the experiences of women in relation to the care received by the healthcare staff at the moment of delivery. METHODS: Qualitative study using the procedures proposed by the Grounded theory for data analysis. The sample comprised 18 women over 14 years of age, between 40 days and 6 months postpartum. Twelve of the participants were selected through convenience and to reach saturation of the categories, six more participants were included by using theoretical sampling...
February 2018: Investigación y Educación en Enfermería
Yixin Zhang, Cong Du, Wei Wang, Wen Chen, Ping Shao, Chongdan Wang, Junhong Leng, Jun Shen, Long Tan, Wanqi Zhang
OBJECTIVE: Neonatal TSH screening is effective in detecting congenital hypothyroidism and estimating iodine status in a given population, but various factors influence TSH levels. The aim of this study was to evaluate the effect of maternal and neonatal factors on neonatal TSH levels. DESIGN AND SETTING: Data were obtained from an ongoing prospective cohort study. A total of 988 pregnant women and their newborn infants participated in the study from April 2015 to May 2017 at Tianjin Maternal and Child Health Center and Tanggu Maternity Hospital in Tianjin, China...
September 2018: Journal of Trace Elements in Medicine and Biology
J D Stock, J A Calderón Díaz, M F Rothschild, B E Mote, K J Stalder
Feet and legs of replacement females were objectively evaluated at selection, i.e. approximately 150 days of age (n=319) and post first parity, i.e. any time after weaning of first litter and before 2nd parturition (n=277) to 1) compare feet and leg joint angle ranges between selection and post first parity; 2) identify feet and leg joint angle differences between selection and first three weeks of second gestation; 3) identify feet and leg join angle differences between farms and gestation days during second gestation; and 4) obtain genetic variance components for conformation angles for the two time points measured...
June 9, 2018: Journal of Animal Science
J L Peine, G Q Jia, M L Van Emon, T L Neville, J D Kirsch, C J Hammer, S T O'Rourke, L P Reynolds, J S Caton
The hypothesis of this study was that arginine supplementation would overcome negative effects of restricted maternal feed intake during the last two-thirds of gestation on ewe performance and positively impact postnatal lamb growth and development. Multiparous, Rambouillet ewes (n = 32) were allocated to 3 treatments in a completely random design at 54 ± 3.9 d of gestation. Dietary treatments were 100% of nutrient requirements (control, CON), 60% of control (restricted, RES), or RES plus a rumen-protected arginine supplement dosed at 180 mg/kg BW once daily (RES-ARG)...
June 9, 2018: Journal of Animal Science
Lauren Richardson, Christopher Luke Dixon, Leopoldo Aguilera-Aguirre, Ramkumar Menon
Term and preterm parturition are associated with oxidative stress (OS)-induced p38 mitogen-activated protein kinase (MAPK)-mediated fetal tissue (amniochorion) senescence. p38MAPK activation is a complex cell and stimulant-dependent process. Two independent pathways of OS-induced p38MAPK activation were investigated in amnion epithelial cells (AECs) in response to cigarette smoke extract (CSE: a validated OS inducer in fetal cells: 1) The OS-mediated oxidation of apoptosis-signaling kinase (ASK)-1 bound Thioredoxin (Trx[SH]2 dissociates this complex, creating free and activated ASK1-signalosome and 2) transforming growth factor mediated activation of (TGF)-beta-activated kinase (TAK)1 and TGF-beta-activated kinase 1-binding protein (TAB)1...
June 11, 2018: Biology of Reproduction
J Lomb, D M Weary, K E Mills, M A G von Keyserlingk
Metritis in dairy cows has been associated with changes in behavior at the feed bunk, but little is known about the effects on behavior at the lying stall. The aim of this study was to investigate stall use by primiparous dairy cows diagnosed with metritis, specifically time spent in the stall, social interactions at the stall, and lying-related behaviors. After parturition, primiparous cows were housed in a mixed-parity pen with a constant group size of 20. Cows had access to 12 electronic feed bins, 2 electronic water bins, and 24 lying stalls...
June 6, 2018: Journal of Dairy Science
Santanu Nath, Rajeev Ranjan, Debadatta Mohapatra, Biswa Ranjan Mishra
Sheehan's syndrome is a neuroendocrine condition that manifests with symptoms of hypopituitarism. It mostly occurs as a complication of parturition due to severe postpartum hemorrhage compromising pituitary circulation. Reports of neuropsychiatric manifestations of Sheehan's syndrome are available with most cases describing psychosis. We report an interesting case of Sheehan's syndrome which presented with catatonia on a psychotic background and its successful management. The possible pathophysiological underpinnings for the causation of catatonia and psychosis in this condition are also discussed...
May 2018: Indian Journal of Psychological Medicine
Takahiro Minato, Takuya Ito, Yoshiyuki Kasahara, Sayaka Ooshio, Tomofumi Fushima, Akiyo Sekimoto, Nobuyuki Takahashi, Nobuo Yaegashi, Yoshitaka Kimura
Fetal growth restriction (FGR) is a risk factor exacerbating a poor neurological prognosis at birth. A disease exacerbating a poor neurological prognosis is cerebral palsy. One of the cause of this disease is cerebral hemorrhage including intraventricular hemorrhage. It is believed to be caused by an inability to autoregulate cerebral blood flow as well as immaturity of cerebral vessels. Therefore, if we can evaluate the function of autonomic nerve, cerebral hemorrhage risk can be predicted beforehand and appropriate delivery management may be possible...
2018: Frontiers in Physiology
Sunita S Jeawon, Lisa M Katz, Noreen P Galvin, Ursula M Fogarty, Vivienne E Duggan
Although umbilical cord blood gas analysis is considered the best way to assess in utero oxygenation in human neonates, there is limited evaluation of this method in equine neonatology. Our objectives were to assess the practicality of obtaining umbilical cord blood gas samples in the field and to determine umbilical cord arterial and venous blood gas reference intervals (RI) for healthy, newborn foals. Thoroughbred foals >320 days gestation from healthy mares with uneventful pregnancies at one stud farm were evaluated...
May 25, 2018: Theriogenology
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