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https://www.readbyqxmd.com/read/28221063/what-five-decades-of-research-tells-us-about-the-effects-of-youth-psychological-therapy-a-multilevel-meta-analysis-and-implications-for-science-and-practice
#1
John R Weisz, Sofie Kuppens, Mei Yi Ng, Dikla Eckshtain, Ana M Ugueto, Rachel Vaughn-Coaxum, Amanda Jensen-Doss, Kristin M Hawley, Lauren S Krumholz Marchette, Brian C Chu, V Robin Weersing, Samantha R Fordwood
Across 5 decades, hundreds of randomized trials have tested psychological therapies for youth internalizing (anxiety, depression) and externalizing (misconduct, attention deficit and hyperactivity disorder) disorders and problems. Since the last broad-based youth meta-analysis in 1995, the number of trials has almost tripled and data-analytic methods have been refined. We applied these methods to the expanded study pool (447 studies; 30,431 youths), synthesizing 50 years of findings and identifying implications for research and practice...
February 2017: American Psychologist
https://www.readbyqxmd.com/read/28202321/anxiety-and-depression-among-sexual-minority-women-and-men-in-sweden-is-the-risk-equally-spread-within-the-sexual-minority-population
#2
Charlotte Björkenstam, Emma Björkenstam, Gunnar Andersson, Susan Cochran, Kyriaki Kosidou
INTRODUCTION: Sexual minority individuals have a higher risk of anxiety and depression compared with heterosexuals. However, whether the higher risk is spread equally across the sexual minority population is not clear. AIM: To investigate the association between sexual orientation and self-reported current anxiety and a history of diagnosis of depression, paying particular attention to possible subgroup differences in risks within the sexual minority population, stratified by sex and to examine participants' history of medical care for anxiety disorders and depression...
February 12, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28201957/chilean-men-exposed-to-the-major-earthquake-in-2010
#3
Oscar Labra, Danielle Maltais, Gilles Tremblay
The article presents the results of a study involving 18 men, 4 years after one of South America's most powerful natural disasters: An earthquake occurring off the coast of Chile in February 2010. Participants reported having developed new psychological health problems in the months following the catastrophe. The manifestations most frequently reported by participants were the presence of depressive and stress symptoms, as well as sleep disorders. The majority of participants registered scores of 33 and above on the Impact of Event Scale-Revised, indicating that they were suffering from posttraumatic stress...
March 2017: American Journal of Men's Health
https://www.readbyqxmd.com/read/28195856/pharmacoepidemiologic-analyses-of-opioid-use-among-oef-oif-ond-veterans
#4
Teresa J Hudson, Jacob T Painter, Brad Martin, Mark A Austen, James S Williams, John Fortney, Mark D Sullivan, Mark E Edlund
There is a great deal of concern about opioid use in Veterans, particularly those that served in Afghanistan (OEF) and Iraq (OIF and OND). The current study provides a detailed pharmacoepidemiologic analysis of opioid use among OEF/OIF/OND Veterans from FY09 to FY12. Data from three data repositories from the Veterans Health Administration (VHA) were used to describe demographic, clinical, and medication characteristics associated with opioid use among OEF/OIF/OND Veterans and among those with TBI. Logistic regression models were used to identify risks associated with chronic opioid use in FY12...
February 11, 2017: Pain
https://www.readbyqxmd.com/read/28187690/needs-of-a-silent-minority
#5
Mary Gowin, E Laurette Taylor, Jamie Dunnington, Ghadah Alshuwaiyer, Marshall K Cheney
Mexican male to female transgender asylum seekers in the United States suffer from serious health issues that can be attributed to stressors related to their transgender, ethnic minority, and socioeconomic status. This study explored these stressors, the resulting health issues, and the needs of this particularly vulnerable population. Asylum seekers' (n = 45) sworn declarations and psychological evaluations were examined by a multidisciplinary research team using a systematic document review process. The review identified stressors that occurred both in Mexico and the United States: verbal, physical, and sexual assaults; unstable environments; fear for safety/security; hiding undocumented status; and economic insecurity...
February 1, 2017: Health Promotion Practice
https://www.readbyqxmd.com/read/28187187/widespread-signatures-of-positive-selection-in-common-risk-alleles-associated-to-autism-spectrum-disorder
#6
Renato Polimanti, Joel Gelernter
The human brain is the outcome of innumerable evolutionary processes; the systems genetics of psychiatric disorders could bear their signatures. On this basis, we analyzed five psychiatric disorders, attention deficit hyperactivity disorder, autism spectrum disorder (ASD), bipolar disorder, major depressive disorder, and schizophrenia (SCZ), using GWAS summary statistics from the Psychiatric Genomics Consortium. Machine learning-derived scores were used to investigate two natural-selection scenarios: complete selection (loci where a selected allele reached fixation) and incomplete selection (loci where a selected allele has not yet reached fixation)...
February 10, 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28182456/the-impact-of-service-connected-disability-and-therapist-experience-on-outcomes-from-prolonged-exposure-therapy-with-veterans
#7
Jason T Goodson, Amy W Helstrom, Emily J Marino, Rachel V Smith
OBJECTIVE: Although prolonged exposure therapy (PE) has been shown to be effective in treating posttraumatic stress disorder (PTSD), a sizable minority do not benefit. Examining patient and therapist characteristics that impact treatment outcome may improve treatment delivery and identify individuals who are less likely to respond to treatment or are at risk to prematurely discontinue treatment. The current study uses a sample from a large urban Veterans' Affairs (VA) hospital to build on a previous report that identified correlates of treatment outcome for Veterans who received PE...
February 9, 2017: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/28158281/is-investigator-background-related-to-outcome-in-head-to-head-trials-of-psychotherapy-and-pharmacotherapy-for-adult-depression-a-systematic-review-and-meta-analysis
#8
Ioana A Cristea, Claudio Gentili, Pietro Pietrini, Pim Cuijpers
BACKGROUND: The influence of factors related to the background of investigators conducting trials comparing psychotherapy and pharmacotherapy has remained largely unstudied. Specializations emphasizing biological determinants of mental disorders, like psychiatry, might favor pharmacotherapy, while others stressing psychosocial factors, like psychology, could promote psychotherapy. Yet financial conflict of interest (COI) could be a confounding factor as authors with a medical specialization might receive more sponsoring from the pharmaceutical industry...
2017: PloS One
https://www.readbyqxmd.com/read/28155207/prodrome-or-risk-syndrome-what-s-in-a-name
#9
Pierre Alexis Geoffroy, Jan Scott
BACKGROUND: In the last decade, an increasing number of publications have examined the precursors of bipolar disorders (BD) and attempted to clarify the early origins and illness trajectory. This is a complex task as the evolution of BD often shows greater heterogeneity than psychosis, and the first onset episode of BD may be dominated by depressive or manic features or both. To date, most of the published reviews have not clarified whether they are focused on prodromes, risk syndromes or addressing both phenomena...
December 2017: International Journal of Bipolar Disorders
https://www.readbyqxmd.com/read/28152244/depression-care-among-depressed-adults-with-and-without-comorbid-substance-use-disorders-in-the-united-states
#10
Beth Han, Mark Olfson, Ramin Mojtabai
OBJECTIVE: We compared the prevalence of receiving depression care between adults with past-year major depressive episodes (depressed) and substance use disorders (SUD) in the United States and their depressed counterparts without SUD. METHOD: Data were from 25,500 adults who participated in the 2008-2014 National Surveys on Drug Use and Health. Descriptive analyses and logistic regression models were applied. RESULTS: During 2008-2014, approximately 55...
February 2, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28151093/acupuncture-for-the-treatment-of-adults-with-posttraumatic-stress-disorder-a-systematic-review-and-meta-analysis
#11
Sean Grant, Benjamin Colaiaco, Aneesa Motala, Roberta Shanman, Melony Sorbero, Susanne Hempel
Acupuncture has been suggested as a treatment for posttraumatic stress disorder (PTSD), yet its clinical effects are unclear. This review aims to estimate effects of acupuncture on PTSD symptoms, depressive symptoms, anxiety symptoms, and sleep quality for adults with PTSD. We searched 10 databases in January 2016 to identify eligible randomized controlled trials (RCTs). We performed random effects meta-analyses and examined quality of the body of evidence (QoE) using the GRADE approach to rate confidence in meta-analytic effect estimates...
February 2, 2017: Journal of Trauma & Dissociation
https://www.readbyqxmd.com/read/28149649/hepatitis-c-virus-infection-and-neurological-and-psychiatric-disorders-a-review
#12
REVIEW
Lydia Yarlott, Eleanor Heald, Daniel Forton
An association between hepatitis C virus infection and neuropsychiatric symptoms has been proposed for some years. A variety of studies have been undertaken to assess the nature and severity of these symptoms, which range from fatigue and depression to defects in attention and verbal reasoning. There is evidence of mild neurocognitive impairment in some patients with HCV infection, which is not fully attributable to liver dysfunction or psychosocial factors. Further evidence of a biological cerebral effect has arisen from studies using magnetic resonance spectroscopy; metabolic abnormalities correlate with cognitive dysfunction and resemble the patterns of neuroinflammation that have been described in HIV infection...
March 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/28144887/phytochemical-screening-acute-toxicity-anxiolytic-and-antidepressant-activities-of-the-nelumbo-nucifera-fruit
#13
Muhammad Ali Rajput, Rafeeq Alam Khan
Recently use of herbal therapies and diet rich in flavonoids and vitamin C have increased significantly to treat minor to modest anxiety disorders and various forms of depression. But further research and studies are necessary to evaluate the pharmacological & toxicological effects of plants. Hence present study was designed to conduct phytochemical screening, acute toxicity study, anxiolytic and antidepressant activities of the ethanol extract of Nelumbo nucifera fruit in order to ascertain its therapeutic potential...
February 1, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/28138107/measurement-based-treatment-of-residual-symptoms-using-clinically-useful-depression-outcome-scale-korean-validation-study
#14
Sang Won Jeon, Changsu Han, Young-Hoon Ko, Seo Young Yoon, Chi-Un Pae, Joonho Choi, Yong Chon Park, Jong-Woo Kim, Ho-Kyoung Yoon, Seung-Duk Ko, Ashwin A Patkar, Mark Zimmerman
Objective: This study was aimed at evaluating the diagnostic validity of the Korean version of the Clinically Useful Depression Outcome Scale (CUDOS) with varying follow-up in a typical clinical setting in multiple centers. Methods: In total, 891 psychiatric outpatients were enrolled at the time of their intake appointment. Current diagnostic characteristics were examined using the Structured Clinical Interview for DSM-IV (41% major depressive disorder). The CUDOS was measured and compared with three clinician rating scales and four self-report scales...
February 28, 2017: Clinical Psychopharmacology and Neuroscience: the Official Scientific Journal of the Korean College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28135835/clinical-use-of-nutraceuticals-in-the-adjunctive-treatment-of-depression-in-mood-disorders
#15
Jerome Sarris
OBJECTIVES: The aim of this paper is to detail a summary of the current evidence in this area, to better inform clinical practice. Our recent systematic reviews and meta-analyses of nutrient pharmacotherapies in the treatment unipolar depression revealed primarily positive results for replicated studies testing S-adenosyl methionine (SAMe), methylfolate, omega-3 (EPA or ethyl-EPA), and Vitamin D; with supportive isolated studies found for creatine and an amino acid combination. Mixed results were found for zinc, folic acid, Vitamin C, and tryptophan; and non-significant study results for inositol...
January 1, 2017: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/28103415/predictors-of-ptsd-symptom-change-among-outpatients-in-the-u-s-department-of-veterans-affairs-health-care-system
#16
Rebecca K Sripada, Paul N Pfeiffer, Jessica Rampton, Dara Ganoczy, Sheila A M Rauch, Melissa A Polusny, Kipling M Bohnert
Although the U.S. Department of Veterans Affairs (VA) has prioritized care for posttraumatic stress disorder (PTSD), many patients with PTSD remain symptomatic. Patterns of PTSD symptom change are not well understood. Thus, the current study was designed to categorize and investigate potential predictors of symptom trajectories in patients with PTSD. The sample comprised 2,237 VA patients who were diagnosed with PTSD in 2013 and completed at least 4 PTSD Checklist (PCL) assessments over 12 weeks. Latent trajectory analysis was used to identify latent classes of patients based on PCL scores...
February 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/28096882/design-and-methods-of-the-mood-disorder-cohort-research-consortium-mdcrc-study
#17
Chul-Hyun Cho, Yong-Min Ahn, Se Joo Kim, Tae Hyun Ha, Hong Jin Jeon, Boseok Cha, Eunsoo Moon, Dong Yeon Park, Ji Hyun Baek, Hee-Ju Kang, Vin Ryu, Hyonggin An, Heon-Jeong Lee
The Mood Disorder Cohort Research Consortium (MDCRC) study is designed as a naturalistic observational prospective cohort study for early-onset mood disorders (major depressive disorders, bipolar disorders type 1 and 2) in South Korea. The study subjects consist of two populations: 1) patients with mood disorders under 25 years old and 2) patients with mood disorders within 2 years of treatment under 35 years old. After successful screening, the subjects are evaluated using baseline assessments and serial follow-up assessments at 3-month intervals...
January 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/28069620/prenatal-exposure-to-antiepileptic-drugs-and-use-of-primary-healthcare-during-childhood-a-population-based-cohort-study-in-denmark
#18
Anne Mette Würtz, Dorte Rytter, Claus Høstrup Vestergaard, Jakob Christensen, Mogens Vestergaard, Bodil Hammer Bech
OBJECTIVE: Prenatal exposure to antiepileptic drugs (AEDs) has been associated with adverse outcomes in the offspring such as congenital malformations and neuropsychiatric disorders. The objective of this study was to investigate whether prenatal exposure to AEDs is also associated with more frequent use of primary healthcare during childhood. DESIGN: Population-based cohort study. SETTING: Nationwide national registers in Denmark. PARTICIPANTS: All live-born singletons in Denmark during 1997-2012 identified in the Danish National Patient Register and followed until 31 December 2013 (n=963 010)...
January 5, 2017: BMJ Open
https://www.readbyqxmd.com/read/28064028/resilient-empowered-active-living-with-diabetes-real-diabetes-study-methodology-and-baseline-characteristics-of-a-randomized-controlled-trial-evaluating-an-occupation-based-diabetes-management-intervention-for-young-adults
#19
Elizabeth A Pyatak, Kristine Carandang, Cheryl Vigen, Jeanine Blanchard, Paola A Sequeira, Jamie R Wood, Donna Spruijt-Metz, Robin Whittemore, Anne L Peters
OVERVIEW: This paper describes the study protocol used to evaluate the Resilient, Empowered, Active Living with Diabetes (REAL Diabetes) intervention and reports on baseline characteristics of recruited participants. REAL Diabetes is an activity-based intervention designed to address the needs of young adults diagnosed with type 1 (T1D) or type 2 diabetes (T2D) from low socioeconomic status or racial/ethnic minority backgrounds. The REAL intervention incorporates tailored delivery of seven content modules addressing various dimensions of health and well-being as they relate to diabetes, delivered by a licensed occupational therapist...
March 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28061411/the-12-month-prevalence-of-depression-and-health-care-utilization-in-the-general-population-of-latvia
#20
Jelena Vrublevska, Marcis Trapencieris, Sigita Snikere, Daiga Grinberga, Biruta Velika, Iveta Pudule, Elmars Rancans
BACKGROUND: This cross-sectional study aims to assess the 12-month prevalence of major and minor depression in the Latvian population, and to evaluate associated health care utilization. METHODS: Trained interviewers conducted face-to-face interviews with a multistage stratified probability sample of the Latvian general population, ages 15-64 (n=3003). Participants were interviewed using the depression module of the Mini International Neuropsychiatric Interview...
December 28, 2016: Journal of Affective Disorders
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