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https://www.readbyqxmd.com/read/28916954/discrimination-and-mental-health-in-a-representative-sample-of-african-american-and-afro-caribbean-youth
#1
Lee M Pachter, Cleopatra H Caldwell, James S Jackson, Bruce A Bernstein
BACKGROUND: Racism and discrimination are psychosocial stressors that affect the health of minority populations. While discrimination has been associated with poor mental health, little is known about the relationship between discrimination and mental health outcomes in youth nationally. Furthermore, mental and behavioral health consequences of discrimination may differ in different minority groups. OBJECTIVE: The goal of this study is to determine (1) how common perceptions of discrimination are in a nationally representative sample of African-American (AA) and Afro-Caribbean (AC) teens, (2) the relationship between discrimination and mental health conditions, and (3) whether discrimination has different associations with mental health in AA and AC youth...
September 15, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/28901829/resilience-to-discrimination-and-rejection-among-young-sexual-minority-males-and-transgender-females-a-qualitative-study-on-coping-with-minority-stress
#2
Laura Jane Bry, Brian Mustanski, Robert Garofalo, Michelle Nicole Burns
Sexual minority and transgender status is associated with mental health disparities, which have been empirically and theoretically linked to stressors related to social stigma. Despite exposure to these unique stressors, many sexual minority and transgender individuals will not experience mental health disorders in their lifetime. Little is known about the specific processes that sexual minority and transgender youth use to maintain their wellbeing in the presence of discrimination and rejection. Semi-structured interviews were conducted with 10 sexual minority males and transgender females aged 18-22 years, who currently met criteria for an operationalized definition of resilience to depression and anxiety...
September 13, 2017: Journal of Homosexuality
https://www.readbyqxmd.com/read/28899525/restless-legs-syndrome-after-high-risk-tia-and-minor-stroke-association-with-reduced-quality-of-life
#3
Mark I Boulos, Anthony Wan, Sandra E Black, Andrew S Lim, Richard H Swartz, Brian J Murray
BACKGROUND: Restless legs syndrome (RLS) is a movement disorder that is associated with poor quality of life and depressive symptoms in the general population. Emerging evidence suggests that RLS is closely associated with cerebrovascular disease. We assessed the effect of RLS on quality of life after stroke and transient ischemic attack (TIA). METHODS: In this single-center prospective study, we recruited patients within 14 days of high-risk TIA or minor stroke...
September 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28889338/german-validation-of-the-quality-of-life-profile-for-spinal-disorders-qlpsd
#4
Tobias L Schulte, Meinald T Thielsch, Georg Gosheger, Patrick Boertz, Jan Henrik Terheyden, Mark Wetterkamp
BACKGROUND: The Quality of Life Profile for Spine Deformities (QLPSD) is a self-reporting questionnaire designed for studying patients with spinal deformities. PURPOSE: The aim of the present study was to systematically translate the QLPSD into German (G-QLPSD) and to test its reliability and validity. Special emphasis was intended to be given to patients with different Cobb angles and ages. METHODS: The QLPSD was systematically translated into German and was responded to in a web-based online survey by patients with idiopathic scoliosis and by healthy control individuals to carry out a matched-pair analysis...
September 9, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28886448/exploring-hepsin-functional-genetic-variation-association-with-disease-specific-protein-expression-in-bipolar-disorder-applications-of-a-proteomic-informed-genomic-approach
#5
Malik Nassan, Yun-Fang Jia, Greg Jenkins, Colin Colby, Scott Feeder, Doo-Sup Choi, Marin Veldic, Susan L McElroy, David J Bond, Richard Weinshilboum, Joanna M Biernacka, Mark A Frye
In a prior discovery study, increased levels of serum Growth Differentiation Factor 15 (GDF15), Hepsin (HPN), and Matrix Metalloproteinase-7 (MMP7) were observed in bipolar depressed patients vs controls. This exploratory post-hoc analysis applied a proteomic-informed genomic research strategy to study the potential functional role of these proteins in bipolar disorder (BP). Utilizing the Genotype-Tissue Expression (GTEx) database to identify cis-acting blood expression quantitative trait loci (cis-eQTLs), five eQTL variants from the HPN gene were analyzed for association with BP cases using genotype data of cases from the discovery study (n = 58) versus healthy controls (n = 777)...
July 4, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28881836/the-prevalence-of-depression-in-rheumatoid-arthritis-in-china-a-systematic-review
#6
Xin Fu, Zhi-Jun Li, Chun-Jun Yang, Liangshu Feng, Lemeng Sun, Yang Yao, Yu-Ting Huang
This systematic review is to explore the prevalence of depression in patients with rheumatoid arthritis (RA) in China. Articles of prevalence rates for depression in adult RA patients published before October 2015 were identified from PubMed, Embase, The Cochrane Library, CNKI, CBM, VIP, and Wanfang database and other internet databases. Relevant journals and the recommendations of expert panels were also searched manually. Two independent reviewers searched and assessed the literature. Therelevant data were applied with Meta-Analyst 3...
August 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28871019/biopsychosocial-factors-associated-with-non-recovery-after-a-minor-transport-related-injury-protocol-for-a-systematic-review
#7
Stella Samoborec, Rasa Ruseckaite, Lorena Romero, Sue M Evans
INTRODUCTION: Globally, road transport accidents contribute substantially to the number of deaths and also to the burden of disability. Up to 50 million people suffer a transport-related non-fatal injury each year, which often leads to long-term disability. It has been shown that substantial number of people with minor injuries struggle to recover and the reasons are still not well explored.Despite the high prevalence, little is known about the factors hindering recovery following minor traffic-related injuries...
September 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/28852030/the-association-between-substance-p-and-white-matter-integrity-in-medication-naive-patients-with-major-depressive-disorder
#8
Eunsoo Won, June Kang, Sunyoung Choi, Aram Kim, Kyu-Man Han, Ho-Kyoung Yoon, Su-Hee Cho, Woo-Suk Tae, Min-Soo Lee, Sook-Haeng Joe, Yong-Ku Kim, Byung-Joo Ham
Substance P (SP) has been implicated in major depressive disorder (MDD), with SP antagonists being studied as potential antidepressants. Although impaired neural plasticity is considered a key mechanism in MDD pathophysiology, the association between SP and brain structural changes in depression has not been investigated. We investigated the correlations between SP levels and white matter (WM) integrity in 42 medication-naive patients with MDD and 57 healthy controls (HCs). Plasma levels of SP were determined, and diffusion tensor imaging (DTI) was performed to investigate microstructural changes in WM tracts...
August 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28844626/associations-of-tumor-necrosis-factor-%C3%AE-and-interleukin-1%C3%AE-levels-and-polymorphisms-with-post-stroke-depression
#9
Jae-Min Kim, Hee-Ju Kang, Ju-Wan Kim, Kyung-Yeol Bae, Sung-Wan Kim, Joon-Tae Kim, Man-Seok Park, Ki-Hyun Cho
OBJECTIVE: Proinflammatory cytokines have been implicated in the pathophysiology of post-stroke depression (PSD), and their production levels are influenced by the transcriptional activity of genetic polymorphisms. The present study aimed to investigate the roles of tumor necrosis factor (TNF)-α and interleukin (IL)-1β in the serum on the risk of PSD while taking into account the TNF-α -850C/T and -308G/A polymorphisms and the IL-1β -511C/T and +3953C/T polymorphisms. METHODS: A total of 286 patients were evaluated at 2 weeks post stroke and 222 (78%) of these patients were followed up 1 year later...
July 25, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28810382/age-moderates-the-relationship-between-source-of-social-support-and-mental-health-in-racial-minority-lesbian-gay-and-bisexual-youth
#10
Anna E Wise, Brian C Smith, Aaron P Armelie, Jessica M Boarts, Douglas L Delahanty
We examined the relationship between source of social support and mental health (and the moderating impact of age) in 64 low socioeconomic status, racial minority lesbian, gay, and bisexual adolescents/young adults. Social support from family ( β = -.302, p = .03; β = -.364, p = .008), but not friends or significant others, was independently related to posttraumatic stress disorder and depression symptoms, respectively. Family social support was associated with lower posttraumatic stress disorder and depression symptoms in participants aged 16-19 years, while friend social support was associated with lower symptoms for participants aged over 20 years...
January 1, 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28809613/enrolling-hiv-positive-adolescents-in-mental-health-research-a-case-study-reflecting-on-legal-and-ethical-complexities
#11
Nataly Woollett, John Peter, Lucie Cluver, Heena Brahmbhatt
BACKGROUND: Adolescents living with HIV are an emerging group in the global HIV/AIDS epidemic. Mental health in this population affects HIV care, treatment, consequential morbidity and secondary transmission. There is a paucity of research regarding these youth in South Africa (SA), partly because section 71 of the National Health Act of 2003 (NHA) requires parental or guardian's consent. OBJECTIVE: To explore legal and ethical issues related to conducting adolescent mental health research in SA...
July 28, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28807138/prevalence-and-predictors-of-post-stroke-mood-disorders-a-meta-analysis-and-meta-regression-of-depression-anxiety-and-adjustment-disorder
#12
Alex J Mitchell, Bhavisha Sheth, John Gill, Motahare Yadegarfar, Brendon Stubbs, Mohammad Yadegarfar, Nick Meader
OBJECTIVE: To ascertain the prevalence and predictors of mood disorders, determined by structured clinical interviews (ICD or DSM criteria) in people after stroke. METHODS: Major electronic databases were searched from inception to June 2016 for studies involving major depression (MDD), minor depression (MnD), dysthymia, adjustment disorder, any depressive disorder (any depressive disorder) and anxiety disorders. Studies were combined using both random and fixed effects meta-analysis and results were stratified as appropriate...
July 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/28806734/mental-health-among-single-and-partnered-parents-in-south-korea
#13
Kyoung Ae Kong, Hee Yeon Choi, Soo In Kim
OBJECTIVE: This study compares the mental health of single parents relative to partnered parents and assesses the contribution of the social and demographic factors to this difference, examining the gender difference in it. METHODS: We analyzed 12,024 single and partnered subjects, aged 30-59 years, living with children, aged 0-19 years, drawn from the 4th, 5th, and 6th Korea National Health and Nutrition Examination Survey (KNHANES) dataset in South Korea conducted from 2007-2013...
2017: PloS One
https://www.readbyqxmd.com/read/28802919/nonmotor-signs-in-genetic-forms-of-parkinson-s-disease
#14
Meike Kasten, Connie Marras, Christine Klein
Although only a minority (i.e., ~5%) of Parkinson's disease (PD) cases is due to well-defined genetic causes, important clues about the common, "idiopathic" PD (iPD) can be garnered from monogenic model diseases. Nonmotor signs (NMS) are also present in monogenic PD and reviewed in this chapter for the confirmed PD genes SNCA, LRRK2, VPS35, Parkin, PINK1, DJ-1, and the risk factor gene GBA. Within the context of the MDSGene database (www.mdsgene.org), we performed a systematic literature search and extracted information on cognitive decline, depression, psychotic signs and symptoms, autonomic signs and symptoms, anxiety, sleep disorder, and olfactory impairment...
2017: International Review of Neurobiology
https://www.readbyqxmd.com/read/28801926/internet-delivered-eating-disorder-prevention-a-randomized-controlled-trial-of-dissonance-based-and-cognitive-behavioral-interventions
#15
Taona P Chithambo, Stanley J Huey
OBJECTIVE: The current study evaluated two web-based programs for eating disorder prevention in high-risk, predominantly ethnic minority women. METHOD: Two hundred and seventy-one women with elevated weight concerns were randomized to Internet dissonance-based intervention (DBI-I), Internet cognitive-behavioral intervention (CBI-I), or no intervention (NI). Both interventions consisted of four weekly online sessions. Participants were assessed at pre- and post-intervention...
August 11, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28798699/schizophrenia-or-atypical-lupus-erythematosus-with-predominant-psychiatric-manifestations-over-25%C3%A2-years-case-analysis-and-review
#16
Axel Mack, Christiane Pfeiffer, E Marion Schneider, Karl Bechter
We observed a case over 25 years of relapsing-remitting schizophrenic spectrum disorder, varying regarding the main symptomatology between more depressive or more schizoaffective or rather typical schizophrenic syndrome. Diseased phases were repeatedly accompanied by minor skin lesions, which were initially classified as mixed tissue disorder. Psychotic phases were waxing-waning over years. During one later relapse, skin involvement was severe, classified to likely represent an allergic reaction to psychopharmaca; this generalized exanthema remitted rapidly with cortisone treatment and azathioprine...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28777363/-sleep-disturbances-an-important-factor-in-combination-minor-symptoms-of-multiple-sclerosis
#17
E Z Yakupov, Yu V Troshina
AIM: To investigate the clinical and neurophysiological features of sleep disorders in patients with different forms of multiple sclerosis (MS) and their impact on life quality, dynamic and prognosis of the disease. Identify the impact of sleep disorders on the formation and maintenance of chronic fatigue syndrome in patients with MS. MATERIAL AND METHODS: General clinical methods of examination like neuropsychological testing (definition of anxiety and depression), the scales of the subjective determination of the quality of sleep, the severity of daytime sleepiness, quality of life, severity of chronic fatigue syndrome) and their subsequent correlation with neuroimaging and neurophysiological data were studied...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28767020/personality-and-its-relation-to-mental-and-psychosocial-health-in-emerging-adult-sexual-minority-men-the-p18-cohort-study
#18
Paul A D'Avanzo, Staci C Barton, Farzana Kapadia, Perry N Halkitis
Personality disorder and personality pathology encompass a dimension of psychological dysfunction known to severely impact multiple domains of functioning. However, there is a notable dearth of research regarding both the pervasiveness and correlates of personality pathology among young sexual minority males who themselves experience heightened mental health burdens. Using the self-report version of the Standardized Assessment of Personality-Abbreviated Scale we tested associations between distinct personality characteristics with sociodemographic and psychosocial factors as well as mental health states in a sample of 528 young (aged 21-25 years) sexual minority men...
July 2017: Behavioral Medicine
https://www.readbyqxmd.com/read/28764654/association-of-restless-legs-syndrome-and-mortality-in-end-stage-renal-disease-an-analysis-of-the-united-states-renal-data-system-usrds
#19
Joseph J DeFerio, Usha Govindarajulu, Amarpali Brar, Daniel Cukor, Kathleen G Lee, Moro O Salifu
BACKGROUND: Objective of the study is to assess prevalence and survival among end stage renal disease patients with restless legs syndrome (RLS) within a national database (USRDS). METHODS: A case-control, retrospective analysis was performed. Differences in characteristics between the groups, RLS and those with no sleep disorder (NSD), were determined using χ2 tests. Cox proportional hazard regression was used to assess survival between those with RLS and propensity score matched controls...
August 1, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28764275/study-of-association-of-substance-use-disorders-with-family-members-psychological-disorders
#20
Kamal Solati, Ali Hasanpour-Dehkordi
INTRODUCTION: Substance Use Disorders (SUDs) represents a serious problem in Iranian community that may lead to psychological disorders in families. AIM: This study was conducted to investigate the association of SUDs with family members' psychological disorders. MATERIALS AND METHODS: The sample size of the study consisted of 724 people referred to a counseling and psychology clinic in Shahrekord, southwest Iran. For data gathering, random method was adopted...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
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