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https://www.readbyqxmd.com/read/28528291/the-association-of-lifetime-physical-inactivity-with-bladder-and-renal-cancer-risk-a-hospital-based-case-control-analysis
#1
Rikki Cannioto, John Lewis Etter, Lauren Beryl Guterman, Janine M Joseph, Nicholas R Gulati, Kristina L Schmitt, Michael J LaMonte, Ryan Nagy, Albina Minlikeeva, James Brian Szender, Kirsten B Moysich
OBJECTIVES: Recreational physical inactivity has been gaining recognition as an independent epidemiological exposure of interest in relation to cancer endpoints due to evidence suggesting that it may associate with cancer independent of obesity. In the current analyses, we examined the associations of lifetime recreational physical inactivity with renal and bladder cancer risk. METHODS: In this hospital-based case-control study, we identified N=160 renal cancer patients, N=208 bladder cancer patients, and N=766 age frequency-matched controls without cancer...
May 18, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28528231/neurocognitive-dysfunction-in-problem-gamblers-with-co-occurring-antisocial-personality-disorder
#2
Austin W Blum, Eric W Leppink, Jon E Grant
OBJECTIVES: Problem gamblers with symptoms of antisocial personality disorder (ASPD) may represent a distinct problem gambling subtype, but the neurocognitive profile of individuals affected by both disorders is poorly characterized. METHOD: Non-treatment-seeking young adults (18-29years) who gambled ≥5 times in the preceding year were recruited from the general community. Problem gamblers (defined as those meeting ≥1 DSM-5 diagnostic criteria for gambling disorder) with a lifetime history of ASPD (N=26) were identified using the Mini International Neuropsychiatric Interview (MINI) and compared with controls (N=266) using questionnaire-based impulsivity scales and objective computerized neuropsychological tasks...
May 12, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28527657/clinical-outcomes-and-cost-effectiveness-of-brief-guided-parent-delivered-cognitive-behavioural-therapy-and-solution-focused-brief-therapy-for-treatment-of-childhood-anxiety-disorders-a-randomised-controlled-trial
#3
Cathy Creswell, Mara Violato, Hannah Fairbanks, Elizabeth White, Monika Parkinson, Gemma Abitabile, Alessandro Leidi, Peter J Cooper
BACKGROUND: Half of all lifetime anxiety disorders emerge before age 12 years; however, access to evidence-based psychological therapies for affected children is poor. We aimed to compare the clinical outcomes and cost-effectiveness of two brief psychological treatments for children with anxiety referred to routine child mental health settings. We hypothesised that brief guided parent-delivered cognitive behavioural therapy (CBT) would be associated with better clinical outcomes than solution-focused brief therapy and would be cost-effective...
May 17, 2017: Lancet Psychiatry
https://www.readbyqxmd.com/read/28527411/trends-in-reports-of-driving-following-illicit-drug-consumption-among-regular-drug-users-in-australia-2007-2013-has-random-roadside-drug-testing-had-a-deterrent-effect
#4
Danielle Horyniak, Paul Dietze, Simon Lenton, Rosa Alati, Raimondo Bruno, Allison Matthews, Courtney Breen, Lucy Burns
INTRODUCTION: Driving following illicit drug consumption ('drug-driving') is a potential road safety risk. Roadside drug testing (RDT) is conducted across Australia with the dual aims of prosecuting drivers with drugs in their system and deterring drug-driving. We examined trends over time in self-reported past six-month drug-driving among sentinel samples of regular drug users and assessed the impact of experiences of RDT on drug-driving among these participants. METHODS: Data from 1913 people who inject drugs (PWID) and 3140 regular psychostimulant users (RPU) who were first-time participants in a series of repeat cross-sectional sentinel studies conducted in Australian capital cities from 2007 to 2013 and reported driving in the past six months were analysed...
May 17, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28526147/pharmacologic-considerations-of-anesthetic-agents-in-geriatric-patients
#5
REVIEW
Maunak V Rana, Lara K Bonasera, Gregory J Bordelon
Aging is a natural process of declining organ function and reserve. Census data show that the geriatric population is expected to grow to nearly 30%. More than half of geriatric patients have 1 or more surgical procedures in their lifetimes. Moreover, this is the population at greatest risk of morbidity and mortality with any given complication. There is remarkable variability in health across the age spectrum, from fit to frail and compromised. This variability requires a unique approach to anesthetic delivery and drug dosing on an individual basis to avoid complications such as postoperative cognitive dysfunction and delirium...
June 2017: Anesthesiology Clinics
https://www.readbyqxmd.com/read/28524713/usual-alcohol-consumption-and-risks-for-nonfatal-fall-injuries-in-the-united-states-results-from-the-2004-2013-national-health-interview-survey
#6
Chiung M Chen, Young-Hee Yoon
BACKGROUND: Acute alcohol consumption is known to be a risk factor for fall injuries. OBJECTIVE: The study sought to determine whether usual alcohol consumption increases the risk for nonfatal fall injuries. METHOD: Data from 289,187 sample adults in the 2004-2013 U.S. National Health Interview Surveys were analyzed. Of these, 3,368 (∼1%) reported a total of 3,579 fall-injury episodes requiring medical consultation in the past 3 months...
May 19, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28523952/is-male-factor-infertility-associated-with-midlife-low-grade-inflammation-a-population-based-study
#7
Katia Keglberg Hærvig, Lene Kierkegaard, Rikke Lund, Helle Bruunsgaard, Merete Osler, Lone Schmidt
Male factor infertility is associated with an increased risk of disease and mortality, which has been related to markers of chronic systemic inflammation. The objective of this study was to investigate the association between male factor infertility and low-grade inflammation and furthermore to examine the lifetime prevalence of male factor infertility and overall infertility (also including female and couple infertility). The study population consisted of 2140 members of the Metropolit 1953 Danish Male Birth Cohort who had participated in the Copenhagen Aging and Midlife Biobank data collection in 2009-2011...
May 19, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28523483/modeling-the-long-term-cost-effectiveness-of-ideglira-in-patients-with-type-2-diabetes-who-are-failing-to-meet-glycemic-targets-on-basal-insulin-alone-in-the-netherlands
#8
Barnaby Hunt, Divina Glah, Maarten van der Vliet
INTRODUCTION: Insulin degludec/liraglutide (IDegLira) is the first basal insulin and glucagon-like peptide-1 receptor agonist (GLP-1 RA) in a single pen injection device, and a once-daily treatment option for patients with type 2 diabetes mellitus (T2DM) who are uncontrolled on basal insulin and require treatment intensification. The objective of this analysis was to evaluate the long-term cost-effectiveness of IDegLira versus basal-bolus therapy (insulin glargine U100 + 3× daily insulin aspart) for patients with T2DM uncontrolled on basal insulin [HbA1c >53 mmol/mol (>7%)] in the Netherlands...
May 18, 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/28523215/migraine-prevalence-in-patients-with-unruptured-intracranial-aneurysms-a-case-control-study
#9
Elbert H Witvoet, Nadine Pelzer, Gisela M Terwindt, Gabriël J E Rinkel, Monique H M Vlak, Ale Algra, Marieke J H Wermer
OBJECTIVES: Migraine is a suggested risk factor for aneurysmal subarachnoid hemorrhage (aSAH). An increased risk of aSAH in migraineurs may be explained by an increased prevalence of unruptured intracranial aneurysms (UIA). We performed a case-control study to compare lifetime migraine prevalence in patients with UIA, patients with a history of transient ischemic attact (TIA) or ischemic stroke and controls without a history of aSAH, TIA or ischemic stroke. MATERIALS AND METHODS: Patients with UIA were recruited from two university hospitals...
May 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28523022/the-prevalence-of-low-back-pain-in-iranian-dentists-an-epidemiological-study
#10
Mohammad Ali Mohseni-Bandpei, Nahid Rahmani, Faezeh Halimi, Muhammad Nazim Farooq
OBJECTIVE: Low back pain (LBP) is one of the most common and prevalent work-related conditions. The aim of this study was to estimate the prevalence and risk factors associated with LBP in dentists and to analyze the association between individual and occupational characteristics and LBP. METHODS: Following ethical approval, 300 dentists from Tehran Iran have voluntarily participated. Different questionnaires were completed to collect personal, occupational characteristics and the prevalence and risk factors of LBP...
March 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28522083/relationships-between-potentially-traumatic-events-sleep-disturbances-and-symptoms-of-ptsd-and-alcohol-use-disorder-in-a-young-adult-sample
#11
Mackenzie J Lind, Allison Baylor, Cassie M Overstreet, Sage E Hawn, Bruce D Rybarczyk, Kenneth S Kendler, Danielle M Dick, Ananda B Amstadter
OBJECTIVE: Traumatic events, particularly those that are interpersonal in nature, are associated with increased risk for co-occurring sequelae, including sleep disturbances, posttraumatic stress disorder (PTSD), and alcohol use disorder (AUD). However, the associations between these phenotypes have not been explored among college students. METHODS: We examined relationships between type of potentially traumatic event (PTE) exposure (pre-college) and sleep disturbances, as well as mediating effects of lifetime PTSD and AUD symptoms on these relationships, in a large undergraduate sample (N = 1599, 64...
June 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28520661/traumatic-brain-injury-and-depression-in-a-community-based-sample-a-cohort-study-across-the-adult-life-span
#12
A J Osborn, J L Mathias, A K Fairweather-Schmidt, K J Anstey
OBJECTIVES: To determine whether self-reported traumatic brain injuries (TBIs) are associated with "cases" of clinically significant depression in the general community. To examine interactions between variables previously linked to depression after a TBI. SETTING: Population-based community study (Canberra and Queanbeyan, Australia). PARTICIPANTS AND DESIGN: Three age cohorts: young, middle-aged, and older adults (aged 20-24, 40-44, and 60-64 years at baseline) randomly selected from the electoral roll and followed across 3 waves (4 years apart)...
May 17, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28520316/the-living-donor-collective-a-scientific-registry-for-living-donors
#13
B L Kasiske, S K Asrani, M A Dew, M L Henderson, C Henrich, A Humar, A K Israni, K L Lentine, A J Matas, K A Newell, D LaPointe Rudow, A B Massie, J J Snyder, S J Taler, J F Trotter, A D Waterman
In the setting of an overall decline in living organ donation and new questions about long-term safety, a better understanding of outcomes after living donation has become imperative. Adequate information on outcomes important to donors may take many years to ascertain and may only be evident by comparing large numbers of donors with suitable controls. Previous studies have been unable to fully answer critical questions, primarily due to lack of appropriate controls, inadequate sample size, and/or follow-up duration too short to allow detection of important risks attributable to donation...
May 18, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28520199/economic-evaluation-of-strategies-for-restarting-anticoagulation-therapy-after-a-first-event-of-unprovoked-venous-thromboembolism
#14
M Monahan, J Ensor, D Moore, D Fitzmaurice, S Jowett
BACKGROUND: Following at least three months of anticoagulation therapy after a first unprovoked Venous Thromboembolism (VTE), there is uncertainty about the duration of therapy. Further anticoagulation therapy reduces the risk of having a potentially fatal recurrent VTE but at the expense of a higher risk of bleeding which can also be fatal. OBJECTIVE: An economic evaluation sought to estimate the long-term cost-effectiveness of using a decision rule for restarting anticoagulation therapy versus no extension of therapy in patients based on their risk of a further unprovoked VTE...
May 18, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28517173/breast-cancer-awareness-among-indonesian-women-at-moderate-to-high-risk
#15
Aira Putri Mardela, Khomapak Maneewat, Hathairat Sangchan
In this descriptive cross-sectional study, we examined awareness of breast cancer among Indonesian women at moderate-to high-risk of developing breast cancer. Data were obtained from 87 eligible participants using the Modified Breast Cancer Awareness Measure. The International Breast Cancer Intervention Study model was used to identify women at moderate-to-high risk of developing breast cancer. The data were analyzed using descriptive statistics. The results showed that none of the participants had knowledge of age-related risk (0%)...
May 18, 2017: Nursing & Health Sciences
https://www.readbyqxmd.com/read/28515780/evolution-and-the-duration-of-a-doomed-population
#16
Richard Gomulkiewicz, Stephen M Krone, Christopher H Remien
Many populations are doomed to extinction, but little is known about how evolution contributes to their longevity. We address this by modeling an asexual population consisting of genotypes whose abundances change independently according to a system of continuous branching diffusions. Each genotype is characterized by its initial abundance, growth rate, and reproductive variance. The latter two components determine the genotype's "risk function" which describes its per capita probability of extinction at any time...
June 2017: Evolutionary Applications
https://www.readbyqxmd.com/read/28515209/for-a-healthier-future-a-virtuous-cycle-for-reducing-exposure-to-persistent-organic-pollutants
#17
REVIEW
Chisato Mori, Emiko Todaka
In the modern society, people are exposed to various pollutants during their lifetime. Worldwide, the status of children's health has changed in recent decades. Some studies have attempted to identify the causes of these changes and whether they relate to pollutant exposure; however, such attempts have faced major challenges because human life is complex, involving many social and environmental factors. Several long-term cohort studies are being conducted to determine the relationship between diseases and social and environmental factors in children...
May 17, 2017: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/28514670/radiation-safety-in-children-with-congenital-and-acquired-heart-disease-a-scientific-position-statement-on-multimodality-dose-optimization-from-the-image-gently-alliance
#18
REVIEW
Kevin D Hill, Donald P Frush, B Kelly Han, Brian G Abbott, Aimee K Armstrong, Robert A DeKemp, Andrew C Glatz, S Bruce Greenberg, Alexander Sheldon Herbert, Henri Justino, Douglas Mah, Mahadevappa Mahesh, Cynthia K Rigsby, Timothy C Slesnick, Keith J Strauss, Sigal Trattner, Mohan N Viswanathan, Andrew J Einstein
There is a need for consensus recommendations for ionizing radiation dose optimization during multi-modality medical imaging in children with congenital and acquired heart disease (CAHD). These children often have complex diseases and may be exposed to a relatively high cumulative burden of ionizing radiation from medical imaging procedures including cardiac computed tomography, nuclear cardiology studies and fluoroscopically guided diagnostic and interventional catheterization and electrophysiology procedures...
May 17, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28514128/-treatment-for-osteoarthritis-of-the-knee
#19
REVIEW
Uriel Giwnewer, Guy Rubin, Hagay Orbach, Nimrod Rozen
Osteoarthritis is the most common joint disorder in the world and its incidence is rising. In Western populations it is one of the most frequent causes of pain, loss of function and disability in adults. The estimated lifetime risk for knee osteoarthritis is approximately 40% in men and 47% in women. The diagnosis of osteoarthritis is complex due to a lack of specific physical and/or laboratorial findings. The American College of Rheumatology (ACR) has recommended using the following criteria for the diagnosis of knee osteoarthritis: chronic knee pain (lasting for more than 6 weeks) and at least three of the following: • Age over 50 years old...
July 2016: Harefuah
https://www.readbyqxmd.com/read/28513052/primary-care-and-cancer-facing-the-challenge-of-early-diagnosis-and-survivorship
#20
Thomas Round
With ageing populations and an increasing lifetime risk of cancer, primary care will continue to play an increasingly important role in early diagnosis and cancer survivorship, especially with the lowering of risk thresholds for referral and diagnostic investigations. However, primary care in many countries is in crisis with increasing workloads for primary care physicians. Potential solutions to these challenges will be outlined including development of multidisciplinary teams, diagnostic decision support, increasing access to diagnostics and cost-effective referral pathways...
May 17, 2017: European Journal of Cancer Care
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