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https://www.readbyqxmd.com/read/28441488/formaldehyde-hcho-as-a-hazardous-air-pollutant-mapping-surface-air-concentrations-from-satellite-and-inferring-cancer-risks-in-the-united-states
#1
Lei Zhu, Daniel J Jacob, Frank N Keutsch, Loretta J Mickley, Richard D Scheffe, Madeleine Strum, Gonzalo González Abad, Kelly Chance, Kai Yang, Bernhard Rappenglueck, Dylan B Millet, Munkhbayar Baasandorj, Lyatt Jaeglé, Viral Pinakin Shah
Formaldehyde (HCHO) is the most important carcinogen in outdoor air among the 187 hazardous air pollutants (HAPs) identified by the US Environmental Protection Agency (EPA), not including ozone and particulate matter. However, surface observations of HCHO are sparse and the EPA monitoring network could be prone to positive interferences. Here we use 2005-2016 summertime HCHO column data from the OMI satellite instrument, validated with high-quality aircraft data and oversampled on a 5 × 5 km(2) grid, to map surface air HCHO concentrations across the contiguous US...
April 25, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28440941/ingestion-of-microplastics-by-fish-and-its-potential-consequences-from-a-physical-perspective
#2
Boris Jovanović
The European Marine Strategy Framework Directive and the United States Microbead Free Waters Act are credited for being ambitious in their goals for protecting the marine environment from microplastics pollution. As a result, the microplastic pollution of marine environments and the incidence of microplastic ingestion by fish is rapidly receiving an increase in overdue attention. This commentary summarizes recent discoveries regarding the potential negative effects of micro- and nanoplastic ingestion by fish...
May 2017: Integrated Environmental Assessment and Management
https://www.readbyqxmd.com/read/28439664/women-at-familial-risk-of-breast-cancer-electing-for-prophylactic-mastectomy-frequencies-procedures-and-decision-making-characteristics
#3
Sarah Schott, Lisa Vetter, Monika Keller, Thomas Bruckner, Michael Golatta, Sabine Eismann, Nicola Dikow, Christina Evers, Christof Sohn, Joerg Heil
BACKGROUND: Some women of families at high risk of breast cancer (BC) choose prophylactic mastectomy (PM) in spite of ambiguous evidence for survival benefits. The aim of this study was to investigate counselees' characteristics, decisions on PM, and frequencies of different procedures to better understand how to tailor interventions. PATIENTS AND METHODS: Eight hundred and forty-nine counselees who attended interdisciplinary consultation for genetic risk adjustment at the University Hospital Heidelberg between July 2009 and July 2011 received a tripartite questionnaire addressing sociodemographic characteristics, psychological parameters, behavioural questions, and medical data...
April 24, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28437379/associations-of-lifetime-trauma-and-chronic-stress-with-c-reactive-protein-in-adults-ages-50-and-older-examining-the-moderating-role-of-perceived-control
#4
Ari J Elliot, Christopher J Mooney, Frank J Infurna, Benjamin P Chapman
OBJECTIVE: To investigate whether high perceived control mitigates systemic inflammatory risk associated with traumatic and chronic stress exposures in older adults. METHODS: A sample of community-dwelling adults ages 50 and older (N=4,779) was drawn from the Health and Retirement Study (HRS). Structural equation models tested interactions of lifetime trauma and chronic stress with mastery and perceived constraints predicting baseline levels and four-year change in C-reactive protein (CRP)...
April 21, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28436695/the-impact-of-childhood-parental-quality-on-mental-health-outcomes-in-older-adults
#5
R A Burns, V Loh, J E Byles, H L Kendig
OBJECTIVE: Parental bonding is cited as a determinant of mental health outcomes in childhood, adolescence and early-mid adulthood. Examination of the long-term impact for older adults is limited. We therefore examine the long-term risk of perceived poor parental bonding on mental health across the lifespan and into early-old age. METHODS: Participants (N = 1255) were aged 60-64 years of age and drawn from the Australian Life Histories and Health study. Quality of parental bonding was assessed with the Parental Bonding Instrument (PBI)...
April 24, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28436345/evidence-that-polygenic-risk-for-psychotic-disorder-is-expressed-in-the-domain-of-neurodevelopment-emotion-regulation-and-attribution-of-salience
#6
J van Os, Y van der Steen, Md A Islam, S Gülöksüz, B P Rutten, C J Simons
BACKGROUND: The liability-threshold model of psychosis risk predicts stronger phenotypic manifestation of the polygenic risk score (PRS) in the healthy relatives of patients, as compared with healthy comparison subjects. METHODS: First-degree relatives of patients with psychotic disorder (871 siblings and 812 parents) and healthy comparison subjects (n = 523) were interviewed three times in 6 years. Repeated measures of two psychosis phenotypes, the Community Assessment of Psychic Experiences (CAPE; self-report - subscales of positive, negative and depressive symptoms) and the Structured Interview for Schizotypy - Revised (SIS-R; clinical interview - subscales of positive and negative schizotypy), were examined for association with PRS...
April 24, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28434249/pulmonary-tuberculosis-is-associated-with-biomass-fuel-use-among-rural-women-in-pakistan-an-age-and-residence-matched-case-control-study
#7
Unaib Rabbani, Ambreen Sahito, Asaad Ahmed Nafees, Ambreen Kazi, Zafar Fatmi
Facility-based, age- and residential area-matched case-control study was conducted in Sindh, Pakistan to determine association between biomass fuel use for cooking and pulmonary tuberculosis (TB). Cases were women with pulmonary TB, and controls were those suffering from other diseases. Current users of biomass fuel were at higher risk of pulmonary TB (adjusted matched odds ratio [mOR] = 3.0; 95% CI = 1.1-4.9) compared with nonusers. In comparison with former biomass users (women not using biomass for >10 years), recent biomass users (women who switched from biomass to nonbiomass ≤10 years ago), and current (lifetime) users were at a higher risk in a dose-response manner (adjusted mOR = 2...
April 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28434211/health-conditions-and-motivations-for-marijuana-use-among-young-adult-medical-marijuana-patients-and-non-patient-marijuana-users
#8
Stephen E Lankenau, Janna Ataiants, Salini Mohanty, Sheree Schrager, Ellen Iverson, Carolyn F Wong
INTRODUCTION: While marijuana has been legal for medical purposes in California since 1996, little is known about the health histories of young adult medical marijuana patients who are a significant proportion of medical marijuana patients. We examined whether young adult medical marijuana patients reported health conditions and motivations for use that were consistent with medical use of marijuana in California. METHODS: Young adults (N = 366) aged 18 to 26 years were sampled in Los Angeles in 2014-2015 and segmented into medical marijuana 'patients' (n = 210), marijuana users with a current recommendation, and non-patient users or 'non-patients' (n = 156), marijuana users who never had a medical marijuana recommendation...
April 23, 2017: Drug and Alcohol Review
https://www.readbyqxmd.com/read/28434201/how-much-alcohol-is-consumed-outside-of-the-lifetime-risk-guidelines-in-australia
#9
Sarah Callinan, Michael Livingston, Robin Room, Paul M Dietze
INTRODUCTION AND AIMS: This study aims to estimate the prevalence of long-term risky drinking within the Australian population and the proportion of standard drinks that is consumed outside of the long-term risk (LTR) guidelines of two Australian standard drinks (ASD) per day. DESIGN AND METHODS: Recruited by phone, 2020 Australian adults with an oversampling of risky drinkers were asked detailed questions about how much alcohol they consumed at a range of locations in 2013...
April 23, 2017: Drug and Alcohol Review
https://www.readbyqxmd.com/read/28433229/splenectomy-is-associated-with-higher-infection-and-pneumonia-rates-among-trauma-laparotomy-patients
#10
Kelly A Fair, Christopher R Connelly, Kyle D Hart, Martin A Schreiber, Jennifer M Watters
Splenectomy increases lifetime risk of thromboembolism (VTE) and is associated with long-term infectious complications, primarily, overwhelming post-splenectomy infection (OPSI). Our objective was to evaluate risk of VTE and infection at index hospitalization post-splenectomy. Retrospective review of all patients who received a laparotomy in the NTDB. Propensity score matching for splenectomy was performed, based on ISS, abdominal abbreviated injury score >3, GCS, sex and mechanism. Major complications, VTE, and infection rates were compared...
April 8, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28432898/cost-effectiveness-of-sensor-augmented-pump-therapy-versus-standard-insulin-pump-therapy-in-patients-with-type-1-diabetes-in-denmark
#11
S Roze, S de Portu, J Smith-Palmer, A Delbaere, W Valentine, M Ridderstråle
AIMS: The use of continuous subcutaneous insulin infusion (CSII) in type 1 diabetes (T1D) has increased in recent years. Sensor-augmented pump therapy (SAP) with low glucose suspend (LGS) (allowing temporary suspension of insulin delivery if blood glucose level falls below a pre-defined threshold level) provides additional benefits over CSII alone, but is associated with higher acquisition costs. Therefore, a cost-effectiveness analysis of SAP+LGS versus CSII in patients with T1D was performed...
February 16, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28432879/seasonal-variation-and-health-risk-assessment-of-organochlorine-compounds-in-urban-soils-of-novi-sad-serbia
#12
Biljana D Škrbić, Vesna Marinković, Igor Antić, Anita Petrović Gegić
The aim of this paper was to determine spatial and seasonal variation of 6 indicator polychlorinated biphenyls (PCBs) and 18 organochlorine pesticides (OCPs) in urban soils of Novi Sad, Serbia. Sixty surface soil samples were collected during both winter and summer season, from different types of locations: schools, recreational areas, residential and industrial zones. Samples were treated using the method of accelerated solvent extraction, which allows simultaneous extraction and clean up of PCBs and OCPs...
April 15, 2017: Chemosphere
https://www.readbyqxmd.com/read/28429958/the-influence-of-violence-victimization-on-sexual-health-behaviors-and-outcomes
#13
Jennifer Latimer, Julia Fleckman, Maeve Wallace, Michele Rountree, Katherine Theall
This study examines the implications of a history of personal violence on health and health behaviors. A secondary analysis of cross-sectional data involving adults (n = 214) from a semirural area in southern Louisiana between October 2008 and December 2010 was conducted to ascertain the association between a personal history of violence victimization and indicators of sexual health behaviors and outcomes: communication with sexual partners about HIV status, consistent condom use, and sexually transmitted infection (STI)...
April 21, 2017: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/28429247/a-review-of-the-novel-application-and-potential-adverse-effects-of-proton-pump-inhibitors
#14
REVIEW
Li-Yuan Yu, Lu-Ning Sun, Xue-Hui Zhang, Yue-Qi Li, Lei Yu, Zi-Qing-Yun Yuan, Ling Meng, Hong-Wen Zhang, Yong-Qing Wang
Proton pump inhibitors (PPIs) are known as a class of pharmaceutical agents that target H(+)/K(+)-ATPase, which is located in gastric parietal cells. PPIs are widely used in the treatment of gastric acid-related diseases including peptic ulcer disease, erosive esophagitis and gastroesophageal reflux disease, and so on. These drugs present an excellent safety profile and have become one of the most commonly prescribed drugs in primary and specialty care. Except for gastric acid-related diseases, PPIs can also be used in the treatment of Helicobacter pylori infection, viral infections, respiratory system diseases, cancer and so on...
April 20, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28428977/19th-workshop-of-the-international-stroke-genetics-consortium-april-28-29-2016-boston-massachusetts-usa-2016-001-mri-defined-cerebrovascular-genomics-the-charge-consortium
#15
S Debette, Y Saba, D Vojinovic, X Jian, H Adams, G Chauhan, M Sargurupremraj, S Kaffashian, J Ding, J C Bis, P Nyquist, K Mather, C Van Duijn, L J Launer, M A Ikram, H Schmidt, W T Longstreth, M Fornage, S Seshadri
The CHARGE consortium is an investigator-initiated collaboration to facilitate meta-analyses of genome-wide association studies (GWAS) and genomic analyses based on next generation sequencing (NGS), among multiple large and well-phenotyped population-based cohort studies around the world (http://www.chargeconsortium.com). Within the neuro-CHARGE working group, we are presenting an update of ongoing genomic studies on MRI-markers of cerebrovascular disease. Large population-based studies have shown that the burden of cerebrovascular disease extends far beyond that of clinical stroke...
March 2017: Neurology. Genetics
https://www.readbyqxmd.com/read/28426958/elucidating-the-role-of-trem2-in-alzheimer-s-disease
#16
REVIEW
Jason D Ulrich, Tyler K Ulland, Marco Colonna, David M Holtzman
Alzheimer's disease (AD) is the sixth leading cause of death in the United States and the most common cause of dementia in the elderly. Genetic factors, such as rare variants in the microglial-expressed gene TREM2, strongly impact the lifetime risk of developing AD. Several recent studies have described dramatic TREM2-dependent phenotypes in mouse models of amyloidosis that point to an important role for TREM2 in regulating the response of the innate immune system to Aβ pathology. Furthermore, elevations in the CSF levels of soluble TREM2 fragments implicate changes in inflammatory pathways as occurring coincident with markers of neuronal damage and the onset of clinical dementia in AD...
April 19, 2017: Neuron
https://www.readbyqxmd.com/read/28426545/sex-differences-in-prescription-opioid-use
#17
Mirsada Serdarevic, Catherine W Striley, Linda B Cottler
PURPOSE OF REVIEW: Recent literature focused on prescription opioids has neglected sex differences in use. Here, we evaluated the recent literature (since 2015) examining sex differences in prescription opioid use. RECENT FINDINGS: Between 2015 and 2016, our review found only eight articles addressing sex differences in prescription opioid use mostly opioid misuse in North America among individuals with chronic pain. Risk factors included depression, pain, and polydrug use...
April 19, 2017: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/28426358/effects-of-workplace-generalized-and-sexual-harassment-on-abusive-drinking-among-first-year-male-and-female-college-students-does-prior-drinking-experience-matter
#18
Kathleen M Rospenda, Kaori Fujishiro, Meredith McGinley, Jennifer M Wolff, Judith A Richman
BACKGROUND: Workplace harassment, a known risk factor for adult drinking, is understudied in college samples, but may help explain observed gender differences in drinking patterns. OBJECTIVE: We examine effects of sexual and generalized workplace harassment on changes in drinking behavior over the first semesters of college, and the extent to which these effects differ based on prematriculation drinking for men and women students. METHOD: Data derive from two waves of a longitudinal study of eight Midwestern colleges and universities...
June 7, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28426348/traumatic-brain-injury-and-lifetime-suicidality-applying-the-interpersonal-psychological-theory-perspective
#19
Claire N Bryson, Robert J Cramer, Adam T Schmidt
The present paper investigates the traumatic brain injury (TBI)-suicide link, assessing whether: (a) TBI accounts for variance in suicide risk, and (b) The Interpersonal-Psychological Theory of Suicide can be applied to TBI status. Matched case-control procedures applied to archival college student health data identified TBI and non-TBI subsamples (84 total). Individuals with a TBI possessed higher suicide risk than those without. Even accounting for the relative influence of strong suicide risk factors (i...
April 20, 2017: Death Studies
https://www.readbyqxmd.com/read/28425238/depression-and-parkinson-disease-prevalence-temporal-relationship-and-determinants
#20
Hale Yapici Eser, Hatice Ayşe Bora, Aslı Kuruoğlu
BACKGROUND/AIM: Comorbidity of depression in Parkinson disease (PD) is a major factor that changes patients' quality of life. However, the neurobiological and sociodemographic risk factors for this comorbidity are not well studied. In this study, we aimed to define the prevalence, temporal relationship, and psychosocial and clinical determinants of depression comorbid with PD. MATERIALS AND METHODS: Fifty-five PD patients were evaluated with SCID, a data form that assessed sociodemographic and PD-related variables, UPDRS III, HAM-D, HAM-A, MMSE, and the Apathy Evaluation Scale...
April 18, 2017: Turkish Journal of Medical Sciences
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