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Carotis pressure

Kemal Atasayan, Tevfik Yoldemir, Sedef Ramoglu, Dilek Gogas Yavuz
OBJECTIVE: To evaluate the endothelial function and structure in patients with hirsutism in reproductive age. STUDY DESIGN: The study was conducted on 69 consecutive women admitted with complaints of hirsutism and 63 voluntary healthy women, as controls. A total of 132 subjects who applied to the Gynecology and Infertility Outpatient Clinics were included. Participants with modified Ferriman Gallway (mFG) score over 8 were considered to be hirsute. The demographic, metabolic, hormonal characteristics, risk factors of cardiovascular disease, CIMT (carotis intima media thickness) and FMD (flow-mediated dilatation) were compared between hirsute women and those in the control group...
November 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Dexuan Wang, Yiqian Zhang, Jinhua Han, Shufang Pan, Ning Xu, Xiuyan Feng, Zhizhi Zhuang, Courtney Caroti, Jieqiu Zhuang, Robert S Hoover, Dingying Gu, Qiyi Zeng, Hui Cai
BACKGROUND: WNK kinase is a serine/threonine kinase that plays an important role in normal blood pressure homeostasis. WNK3 was previously found to enhance the activity of sodium chloride cotransporter (NCC) in Xenopus oocyte. However, the mechanism through which it works remains unclear. METHODS: Using overexpression and siRNA knock-down techniques, the effects of WNK3 on NCC in both Cos-7 and mouse distal convoluted cells were analyzed by Western blot. RESULTS: We found that WNK3 significantly increased NCC protein expression in a dose-dependent manner...
2016: Nephron
Mingli Ji, Yuxia Wang, Lei Wang, Liping Chen, Jing Li
Xuebijing (XBJ) is a Chinese herbal preparation. Previous studies have demonstrated that XBJ injection is able to inhibit the uncontrolled release of endogenous inflammatory mediators, attenuate inflammation, and alleviate organ damage. However, there are no relevant reports on the protective effect of XBJ against left ventricular ischemia/reperfusion (I/R)-induced acute lung injury (ALI). Therefore, the aim of the present study was to evaluate the protective effect of XBJ on ALI induced by left ventricular I/R, and provide evidence for the clinical application of XBJ...
July 2016: Experimental and Therapeutic Medicine
Tolga Kurt, Ahmet Temiz, Ferhat Gokmen, Gurhan Adam, Sedat Ozcan, Ersan Ozbudak, Mustafa Sacar
BACKGROUND: It takes years for atherosclerosis to manifest symptoms. However, it needs to be identified earlier because of the premature cardiovascular risk factors in patients with rheumatoid arthritis (RA). In this study, we aimed to investigate the effect of atherosclerosis on the ankle brachial pressure index (ABPI) and carotis intima media thickness (CIMT) in patients with RA. METHODS: RA patients attending the rheumatology clinic were examined retrospectively; then we called them for the measurements of ABPI and CIMT prospectively...
July 2015: Wiener Klinische Wochenschrift
Marek Matus, Dana Kucerova, Peter Kruzliak, Adriana Adameova, Gabriel Doka, Katarina Turcekova, Jana Kmecova, Jan Kyselovic, Peter Krenek, Uwe Kirchhefer, Frank U Mueller, Peter Boknik, Jan Klimas
Chronic angiotensin-converting enzyme inhibitor (ACEIs) treatment can suppress arrhythmogenesis. To examine whether the effect is more immediate and independent of suppression of pathological remodelling, we tested the antiarrhythmic effect of short-term ACE inhibition in healthy normotensive rats. Wistar rats were administered with enalaprilat (ENA, i.p., 5 mg/kg every 12 h) or vehicle (CON) for 2 weeks. Intraarterial blood pressure in situ was measured in A. carotis. Cellular shortening was measured in isolated, electrically paced cardiomyocytes...
May 2015: Molecular and Cellular Biochemistry
Alper Akın, Hayrettin Hakan Aykan, Tevfik Karagöz
Experiences with invasive cardiac catheterization in low birth weight infants are few. In our clinic, we performed balloon aortic valvuloplasty by antegrade approach in a neonate weighing 1100 g with critical aortic stenosis, patent ductus arteriosus and atrial septal defect. The right femoral vein was accessed with a 4 Fr sheath, and a catheter was placed into the left ventricle from the atrial septal defect along the guidewire for coronary catheter. The aortic valve was passed with guidewire, and the guidewire was placed into the right arteria carotis...
January 2014: Turkish Journal of Pediatrics
M E Atabek, Beray Selver Eklioglu, Nesibe Akyürek, Hayrullah Alp
BACKGROUND: The aim of our study was to evaluate the associations between vitamin D deficiency, the atherosclerosis and metabolic syndrome. METHODS: Two hundred and forty-seven obese children and adolescents, 8-16 years of age (body mass index>95 p) were included in the study. Anthropometric measurements, blood pressure measurements, lipid profile, vitamin D level and carotid intima media thickness (c-IMT) were measured. MS was diagnosed according to IDF criteria...
July 2014: Journal of Pediatric Endocrinology & Metabolism: JPEM
Yumei Luo, Wenling Jiang, Danyan Xu, Deqian Jiang
OBJECTIVE: To observe the effect of pioglitazone on carotid artery intima-media thickness (IMT) and plaque-positive rate in patients with metabolic syndrome, and to find a new way to improve arterial remodeling in patients with metabolic syndrome. METHODS: Patients with metabolic syndrome were randomly divided into a control group (n=60) and a pioglitazone group (n=61). All subjects received basic therapeutic measures, i.e, appropriate medication to control blood pressure, blood sugar and cholesterol...
July 2013: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
Kamil Ríha, Jan Mašek, Radim Burget, Radek Beneš, Eva Závodná
This article describes a novel method for highly accurate and effective localization of the transverse section of the carotis comunis artery in ultrasound images. The method has a high success rate, approximately 97%. Unlike analytical methods based on geometric descriptions of the object sought, the method proposed here can cover a large area of shape variation of the artery under study, which normally occurs during examinations as a result of the pressure on the examined tissue, tilt of the probe, setup of the sonographic device, and other factors...
October 2013: Ultrasound in Medicine & Biology
A A Skripnikov, T I Dolganova, A M Aranovich
Complex neurophysiological examination (rheoencephalography, electroencephalography) was carried out in 12 adolescents 12 to 18 years old in order to reveal the peculiarities of cerebral structures functioning in adolescents with achondroplasia. Some deviations from the normal values were found out: reduced blood filling of the brain vessels in the pools of a. carotis interna and a. vertebralis, rheoencephalographic signs of intracranial hypertension of mild degree and brain cycling characterized by moderate and significant amplitude increase, presence of pathological types (delta-, theta-) of the rhythmics and the reduction of the physiological ones (alpha-, beta-)...
2013: Vestnik Rossiĭskoĭ Akademii Meditsinskikh Nauk
David Karasek, Helena Vaverkova, Milan Halenka, Dagmar Jackuliakova, Zdenek Frysak, Jiri Orsag, Dalibor Novotny
INTRODUCTION: Like hypertension, prehypertension is associated with cardiovascular disease. AIMS: The aim of this study was to evaluate: a) the prevalence of prehypertension/hypertension in individuals with various dyslipidemic phenotypes; b) the relation between blood pressure (BP) and other risk factors for atherosclerosis; c) atherogenic potential of prehypertension by the assessment of intima-media thickness of the arteria carotis communis (IMT). METHODS: 667 clinically asymptomatic subjects were divided into four dyslipidemic phenotypes (DLP) according to apolipoprotein B (apoB) and triglycerides (TG): DLP1 (n=198, normo-apoB/normo-TG), DLP2 (n=179, normo-apoB/hyper-TG), DLP3 (n=87, hyper-apoB/normo-TG), DLP4 (n=203, hyper-apoB/hyper-TG)...
March 2013: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
Xian-zhen Wang, Jia-ye Jiang, Shan-shan Luo
OBJECTIVE: To study the vascular endothelial function recovery and its mechanism of Banxia Baizhu Tianma Decoction (BBTD). METHODS: 54 SH rats were randomly divided into three groups: the blank control group, BBTD group and Captopril treatment group. BBTD (at the daily dose of 4. 320 g crude drug/kg) and Captopril (at the daily dose of 3.375 g/kg) was administered from the 7th week to the 24th week. Another eighteen Wistar-Kyoto rats of the same ages were taken as the control...
June 2011: Chinese Journal of Integrated Traditional and Western Medicine
Albert Császár
The presence of multiple risk factors can multiply exponentially the risk of cardiovascular events, thus cardiovascular diseases are more severe in diabetes mellitus. One of the challenges we face today is the application of drugs that, besides improving glucose homeostasis, also have antiatherosclerotic effect. Such candidates are glitazones, which have pleiotropic efficiency beyond their main effect: they improve distribution of adipose tissue, blood pressure and endothelial function and also have anti-inflammatory and anti-coagulation capacity...
February 2011: Lege Artis Medicinae: új Magyar Orvosi Hírmondó
Sieglinde Zelzer, Nina Fuchs, Gunter Almer, Reinhard B Raggam, Florian Prüller, Martie Truschnig-Wilders, Wolfgang Schnedl, Renate Horejsi, Reinhard Möller, Daniel Weghuber, Rottraut Ille, Harald Mangge
BACKGROUND: Obesity related dyslipidemia, chronic inflammation and oxidative stress were associated with atherosclerotic sequels. We analysed oxidized low-density lipoprotein (oxLDL) plasma levels of 797 participants of the STyrian Juvenile OBesity (STYJOBS) / Early DEteCTion of Atherosclerosis (EDECTA) Study cohort aged from 5 to 50 years. The rationale of STYJOBS/EDECTA is to investigate the preclinical phase of obesity by a well defined cohort of young and middle aged overweight/obese and normal weight subjects...
July 15, 2011: Clinica Chimica Acta; International Journal of Clinical Chemistry
A Nolte, S Secker, T Walker, T O Greiner, B Neumann, P Simon, G Ziemer, H P Wendel
AIM: Coronary artery bypass grafting (CABG) is a standard procedure for treatment of coronary heart disease. Eighty percent of all CABGs are performed with venous grafts which then get exposed to an arterial pressure after surgery. This widely used procedure, however, is complicated by the development of alterations in the vein graft wall, leading to a decreased patency rate and graft failure. This study enlightens the influence of an even moderate arterial pressure on the gene expression of adhesion molecules in venous grafts which play a decisive role for the early induction of atherogenesis...
April 2011: Journal of Cardiovascular Surgery
Harald Mangge, Wilfried Renner, Gunter Almer, Daniel Weghuber, Reinhard Möller, Renate Horejsi
A common T/A polymorphism (rs9939609) in the fat mass and obesity associated (FTO) gene was found associated with early-onset and severe obesity in both adults and children. However, recent observations failed to find associations of FTO with obesity. To investigate the genetic background of early obesity, we analysed the single nucleotide polymorphism (SNP) rs9939609 of FTO in 371 styrian adolescents towards degree of obesity, subcutaneous adipose tissue (SAT)-distribution determined by lipometry, early metabolic and preatherosclerotic symptoms...
2011: Journal of Obesity
Zongling Yao, Yang Lu, Shouying Du, Xiaolan Chen, Yue Wang
OBJECTIVE: To develop an HPLC method for the determination of plasma concentration of jasminoidin and study the pharmacokinetics of jasminoidin in rabbits administered Xingnaojing naristillae by nasal medication. METHOD: After sampling blood from the left arteria carotis of rabbits which were administered Xingnaojing naristillae medication by nasal by 12 mg x kg(-1) (counted by gardenia extract) at 1, 3, 5, 10, 20, 30, 45, 60, 90, 120, 240 min, the plasma samples were dealt with acetonitrile precipitation and HPLC was used to determine the plasma concentration of jasminoidin...
July 2010: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
Maris Dubniks, Johan Persson, Per-Olof Grände
BACKGROUND: We still lack comparing data of the plasma volume (PV)-expanding effect of the most commonly used colloids including dextran 70. This study compares the PV-expanding effects of 6% dextran 70, 5% albumin, and 6% hydroxyethylstarch (HES) 130/0.4 after a standardized hemorrhage. METHODS: The prospective and randomized study on 33 anesthetized adult male guinea pigs involved three groups (n = 11 each); the dextran group, the albumin group, and the HES group...
December 2009: Journal of Trauma
Fatma Ulku Adam, Dilek Torun, Fatma Yigit, Ruya Ozelsancak, Siren Sezer, Fatma Nurhan Ozdemir, Mehmet Haberal
AIM: It has been shown that Hepatitis C virus (HCV) seropositivity and carotis artery plaque formation are independently correlated in the general population. Insulin resistance is also a risk factor for atherosclerosis. The association between HCV and type 2 diabetes mellitus is known. Determination of the impact of HCV on insulin resistance and arterial stiffness in hemodialysis patients would help to prevent related cardiovascular complications. METHODS: Thirty-seven HCV(+) and 30 HCV(-) HD patients were enrolled in this study...
2008: Renal Failure
Yan-hong Yu, Ke-sen Zhao, Shi-peng Gong
OBJECTIVE: To determine the effects of two fluid resuscitation strategies on the changes of hemodynamic variables, serum concentration of tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) in a clinically relevant model of uncontrolled hemorrhagic shock in pregnant rabbits. METHODS: Hemorrhagic shock was induced by bleeding via carotied artery, followed by transection of a medium vessel in gestational sac. Experimental design consisted of three phases, shock phase (0-30 min), prehospital phase (30-90 min) and hospital phase (90-180 min)...
January 2008: Zhonghua Fu Chan Ke za Zhi
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