G De Luca, G G Secco, M Santagostino, L Venegoni, S Iorio, E Cassetti, M Verdoia, L Coppo, C Di Mario, G Bellomo, P Marino
BACKGROUND: Hyperuricemia may be involved in the atherosclerotic process due to endothelial dysfunction and facilitation of smooth muscle cell proliferation. However, debates still exist on the independent role of hyperuricemia, due to its association with several cardiovascular risk factors, such as hypertension, hyperlipidemia, obesity and insulin resistance. Thus, the aim of the current study was to investigate in a consecutive cohort of patients undergoing coronary angiography whether hyperuricemia is associated with the extent of coronary artery disease...
May 2012: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD