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https://www.readbyqxmd.com/read/28225725/clinical-features-of-affected-and-undetached-fellow-eyes-in-patients-with-fevr-associated-rhegmatogenous-retinal-detachment
#1
Miner Yuan, Xiaoyan Ding, Yu Yang, Fang Liu, Jiaqing Li, Xiaoling Liang, Xiongze Zhang, Andina Hu, Zijing Li, Zongyi Zhan, Lin Lu
PURPOSE: To report the clinical characteristics of the affected and fellow eyes in patients with familial exudative vitreoretinopathy-associated rhegmatogenous retinal detachment (FEVR-RRD). METHODS: This was a retrospective observational case series. The affected and fellow eyes were given complete examinations. The age, sex, clinical features of the affected eyes, and varied abnormalities of the fellow eyes were analyzed. RESULTS: Forty-three patients with FEVR-RRD were included...
March 2017: Retina
https://www.readbyqxmd.com/read/28225722/efficacy-of-the-inverted-internal-limiting-membrane-flap-technique-with-vitrectomy-for-retinal-detachment-associated-with-myopic-macular-holes
#2
Ryo Baba, Yoshihiro Wakabayashi, Kazuhiko Umazume, Tomoaki Ishikawa, Hiromichi Yagi, Daisuke Muramatsu, Hiroshi Goto
PURPOSE: To evaluate the anatomical and functional outcome of the inverted internal limiting membrane (ILM) flap technique with vitrectomy for retinal detachment associated with macular hole (MHRD) in highly myopic eyes. METHODS: In this retrospective observational study, 21 eyes with MHRD that underwent vitrectomy with conventional ILM peeling (ILM-peeling group, n = 11) or the inverted ILM flap technique (ILM flap group, n = 10) combined with C3F8 tamponade were enrolled in this study...
March 2017: Retina
https://www.readbyqxmd.com/read/28225721/superficial-foveal-avascular-zone-determined-by-optical-coherence-tomography-angiography-before-and-after-macular-hole-surgery
#3
Takayuki Baba, Masato Kakisu, Tomohiro Nizawa, Toshiyuki Oshitari, Shuichi Yamamoto
PURPOSE: To determine the size of the superficial foveal avascular zone (FAZ) by optical coherence tomography angiography before and after surgery for an idiopathic macular hole. METHODS: A retrospective, observational case series, in which 16 eyes of 16 patients with an idiopathic macular hole were studied. Pars plana vitrectomy was performed with internal limiting membrane peeling. The foveal retinal vasculature was examined by optical coherence tomography angiography, and the area of the superficial FAZ was determined before, and at 1 and 3 months after the surgery...
March 2017: Retina
https://www.readbyqxmd.com/read/28221260/double-arcuate-relaxing-retinotomy-for-a-large-macular-hole
#4
Murat Karacorlu, Isil Sayman Muslubas, Mumin Hocaoglu, Serra Arf, Mehmet Giray Ersoz
PURPOSE: To describe double arcuate relaxing retinotomy as an alternative surgical technique in a case with a secondary large macular hole. METHODS: The management of a patient who developed a large macular hole and macular tractional rhegmatogenous retinal detachment after pars plana vitrectomy for proliferative diabetic retinopathy was retrospectively assessed. Despite surgical procedures, such as dissection of a preretinal membrane from the retina and peeling of the retinal internal limiting membrane, the macular hole could not be closed...
February 17, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28220890/clinical-investigation-of-the-posterior-scleral-contraction-to-treat-macular-traction-maculopathy-in-highly-myopic-eyes
#5
An-Peng Pan, Ting Wan, Shuang-Qian Zhu, Liang Dong, An-Quan Xue
Myopic traction maculopathy (MTM) can cause vision disabilities in highly myopic eyes. This retrospective case series investigated the clinical outcomes of posterior scleral contraction (PSC) using genipin-cross-linked sclera as the material to treat MTM in highly myopic eyes. In total, 32 eyes from 29 highly myopic patients who underwent PSC for MTM were recruited. The changes in best-corrected visual acuity (BCVA) and axial length were evaluated, macular reattachment and macular hole (MH) closure was assessed by optical coherence tomography, and complications were evaluated...
February 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28220252/long-term-surgical-outcomes-of-the-inverted-internal-limiting-membrane-flap-technique-in-highly-myopic-macular-hole-retinal-detachment
#6
Taiga Kinoshita, Yasutaka Onoda, Takatoshi Maeno
BACKGROUND: Pars plana vitrectomy (PPV) procedures are used for the surgical treatment of macular hole retinal detachment (MHRD) associated with high myopia. Re-detachment of the retina has been reported in MHRD associated with high myopia. Our aim was to evaluate the 1-year outcomes of vitrectomy, performed using an inverted internal limiting membrane (ILM) flap technique with gas tamponade, in five cases of MHRD associated with high myopia. METHODS: We performed a retrospective review of medical records of five consecutive cases of highly myopic MHRD...
February 20, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28219426/pseudophakic-cystoid-macular-edema-prevention-and-risk-factors-prospective-study-with-adjunctive-once-daily-topical-nepafenac-0-3-versus-placebo
#7
Sean McCafferty, April Harris, Corin Kew, Tala Kassm, Lisa Lane, Jason Levine, Meisha Raven
BACKGROUND: Define the effectiveness of a topical non-steroidal anti-inflammatory drug (NSAID) added to topical steroid use after uncomplicated phacoemulsification for the prevention of pseudophakic cystoid macular edema (PCME) using a prospective, randomized, double-masked, placebo-controlled clinical study. METHODS: Eyes (1000) were randomized to placebo (497) or nepafenac 0.3% (503) used once daily, post-operatively for 5 weeks at two ophthalmology clinics. Diagnosis of PCME was made by clinical, ocular coherence tomography (OCT), and with fluorescein angiography confirmation...
February 20, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28196050/visualization-of-the-macula-in-gas-filled-eyes-spectral-domain-optical-coherence-tomography-versus-swept-source-optical-coherence-tomography
#8
Seong Joon Ahn, Seung Hoon Park, Byung Ro Lee
PURPOSE: To compare the visualization of the macula between spectral domain optical coherence tomography (SD-OCT) and swept-source OCT (SS-OCT) in gas-filled eyes. METHODS: Sixty-one patients with common indications of gas tamponade, including 27 with macular holes and 34 with rhegmatogenous retinal detachment, who were treated with vitrectomy and gas tamponade were imaged using both SD-OCT (3D-OCT 2000, Topcon, Tokyo, Japan) and SS-OCT (DRI-OCT, Topcon) at 1, 3, and 7 days after the surgery...
February 10, 2017: Retina
https://www.readbyqxmd.com/read/28195624/spontaneous-closure-of-full-thickness-macular-hole-with-epiretinal-membrane-in-vitrectomized-eyes-case-series-and-review-of-literature
#9
Wenlan Zhang, Dilraj S Grewal, Glenn J Jaffe, Tamer H Mahmoud, Sharon Fekrat
The authors describe three vitrectomized eyes that each subsequently developed a full-thickness macular hole (FTMH) that then spontaneously closed and summarize the current literature reporting these rare events. Clinical history, imaging, and course of three patients were reviewed and compiled. All three cases in this series developed a FTMH less than 7 months following vitrectomy (for epiretinal membrane [ERM], n = 1) and retinal detachment (n = 2) that demonstrated spontaneous resolution within 2 months of symptom onset, without intervention...
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28195623/internal-limiting-membrane-peeling-by-23-gauge-endoscopy-for-macular-hole-retinal-detachment-in-a-pathological-myopic-eye
#10
Yiqi Chen, Lijun Shen, Shixin Zhao, Lin Wang, Changbiao Xu
Endoscopic vitrectomy can uniquely circumvent anterior segment opacities and is applied to a wide spectrum of retina diseases with media opacities. However, endoscopic internal limiting membrane (ILM) peeling has not been described. The authors present one case of a retinal detachment caused by a macular hole in a pathological myopic eye combined with severe keratoleukoma. The 1-year outcome after 23-gauge endoscopic ILM peeling was good. This case report demonstrates that ILM peeling with a 23-gauge endoscope, which requires subtle and difficult macular manipulation, is feasible and effectively treats macular holes complicated with anterior segment opacities...
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28139882/oxidized-low-density-lipoprotein-lipid-and-calcium-aggregates-reveal-oxidative-stress-and-inflammation-in-the-conjunctiva-of-glaucoma-patients
#11
Minna Helin-Toiviainen, Seppo Rönkkö, Kai Kaarniranta, Tuomo Puustjärvi, Petri Rekonen, Minna Ollikainen, Hannu Uusitalo
PURPOSE: Conjunctival specimens from primary open-angle glaucoma (POAG), exfoliation glaucoma (ExG) patients and controls were histologically analysed for oxidized low-density lipoprotein (ox-LDL), lipid and calcium aggregates. Our goal was to use them as biomarkers of oxidative stress and inflammation and to evaluate their correlation with glaucoma and impact on surgical outcome. METHODS: Conjunctival samples were obtained from POAG (n = 14) and ExG (n = 17) patients and from control subjects (n = 11) operated for macular hole, retinal detachment or strabismus...
January 31, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28134963/gli1-expression-in-human-epiretinal-membranes
#12
Sohee Jeon, Jiwon Baek, Won Ki Lee
Purpose: We evaluate the expression of Gli1 in human epiretinal membranes (ERM) and correlate this with clinical data. Methods: We prospectively recruited patients with ERM. A total of 33 human ERM specimens were immunolabeled with anti-Gli1 antibody and the number of total cells/hyperfield (HF), Gli1(+) cells/HF, and the percentage of Gli1(+) cells/total cells were calculated. We evaluated the interrelationship of cellular properties and clinical findings, such as presence of diabetic retinopathy (DR), retinal breaks, intraocular inflammation, central foveal thickness, maximal retinal thickness, retinal contraction, lamellar holes, pseudoholes, the attenuation or absence of an inner segment/outer segment (IS/OS) junction/external limiting membrane (ELM), cystic changes, and paravascular inner retinal defects...
January 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28127736/direct-transretinal-removal-of-subfoveal-perfluorocarbon-liquid-the-role-and-timing-of-internal-limiting-membrane-peeling
#13
Stefano De Cillà, Micol Alkabes, Paolo Radice, Elisa Carini, Carlos Mateo
PURPOSE: To describe a case series including 4 patients undergoing direct transretinal aspiration of subfoveal perfluorocarbon liquid (PFCL) and internal limiting membrane (ILM) peeling after macula-off retinal detachment surgery. METHODS: Four patients who had undergone vitreoretinal surgery due to primary rhegmatogenous retinal detachment were further treated because of retained subfoveal PFCL. Direct transretinal aspiration of PFCL through a self-sealing foveal retinotomy was performed in all cases using a 41-G needle placed on the top of the bubble...
January 23, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28124146/aniseikonia-in-various-retinal-disorders
#14
Fumiki Okamoto, Yoshimi Sugiura, Yoshifumi Okamoto, Takahiro Hiraoka, Tetsuro Oshika
PURPOSE: The purpose was to quantify and compare the severity of aniseikonia in patients undergoing vitrectomy for various retinal disorders. METHODS: We studied 357 patients with retinal disorders including epiretinal membrane (ERM), macular hole (MH), cystoid macular edema with branch / central retinal vein occlusion (BRVO-CME / CRVO-CME), diabetic macular edema (DME), macula-off rhegmatogenous retinal detachment (M-off RD), and macula-on RD (M-on RD) as well as 31 normal controls...
January 25, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28121212/macular-hole-in-stargardt-disease-clinical-and-ultra-structural-observation
#15
Stanislao Rizzo, Dario Pasquale Mucciolo, Daniela Bacherini, Vittoria Murro, Lorenzo Vannozzi, Gianni Virgili, Daniele Bani, Andrea Sodi
PURPOSE: To report for the first time a case report of a Stargardt disease patient who developed a macular hole (MH) which was treated with a surgical approach. METHOD: Case report. RESULTS: After vitrectomy a complete closure of the MH was obtained and the best-corrected visual acuity remained stable. No complications were reported after one year of follow-up. An ultra-structural examination of the removed internal limiting membrane (ILM) and epiretinal membrane (ERM) was carried out under electron microscopy...
January 25, 2017: Ophthalmic Genetics
https://www.readbyqxmd.com/read/28114699/-vision-loss-in-association-with-silicone-oil
#16
J Tode, J Roider
Silicone oil tamponades have been a key feature of vitreoretinal surgery for more than 40 years. The use of these durable vitreous substitutes has not only been limited to tractive retinal detachments, inflammatory chorioretinopathies or other complicated vitreoretinal diseases, but also to macular holes and rhegmatogenous retinal detachment. During the last 12 years, an increasing number of cases of vision loss during or after the removal of silicone oil have been reported in the literature. In up to one third of patients with uncomplicated macula-attached retinal detachment with good preoperative vision, continuing vision loss is seen...
January 23, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28112568/vitrectomy-for-epiretinal-membranes-and-macular-holes-in-uveitis-patients
#17
Sara V Branson, Brendan R McClafferty, Shree K Kurup
PURPOSE: Macular pathology, including macular holes (MHs), epiretinal membranes (ERMs), and macular edema, is a cause of irreversible vision loss in the setting of uveitis. Medical management involves corticosteroids, immunomodulatory medications, and biologics to control inflammation. Pars plana vitrectomy (PPV) has been suggested as a therapy for uveitis, with reports of reduced inflammation and decreased dependence on medication postoperatively. Currently, PPV is reserved for retinal detachments, vitreous opacities, and ERMs, causing vitreomacular traction...
January 23, 2017: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28106706/intravitreal-ocriplasmin-in-clinical-practice-predictors-of-success-visual-outcomes-and-complications
#18
Henry L Feng, Daniel B Roth, Aisha Hasan, Howard F Fine, H Matthew Wheatley, Jonathan L Prenner, Sumit P Shah, Kunjal K Modi, William J Feuer
PURPOSE: To investigate predictors of success, visual outcomes, and complications of intravitreal ocriplasmin for the treatment of symptomatic vitreomacular adhesion in a clinical care setting. METHODS: Retrospective chart review of 49 consecutive eyes of 47 patients who received intravitreal ocriplasmin. Spectral domain optical coherence tomography scans were examined for vitreomacular traction (VMT) release, full-thickness macular hole (FTMH) closure, and other changes in retinal anatomy...
January 18, 2017: Retina
https://www.readbyqxmd.com/read/28099316/pneumatic-vitreolysis-for-relief-of-vitreomacular-traction
#19
Clement K Chan, Jason N Crosson, Calvin E Mein, Noha Daher
PURPOSE: To evaluate the outcome of perfluoropropane (C3F8) gas injection for symptomatic vitreomacular traction (VMT) with or without Stage 2 macular hole (MH). METHODS: A retrospective review of eyes with VMT treated with 0.3 mL of C3F8 gas was performed. Patients avoided the supine position until gas resolution. Patients with small MH maintained partial face-down positioning. RESULTS: Forty-nine consecutive patients (50 eyes) with symptomatic VMT underwent pneumatic vitreolysis between 2010 and 2016...
January 17, 2017: Retina
https://www.readbyqxmd.com/read/28060394/results-of-peripheral-vitrectomy-under-air-in-rhegmatogenous-retinal-detachment
#20
Tugrul Altan, Kemal Turgay Ozbilen, Turgay Cetin, Ziya Kapran
BACKGROUND AND OBJECTIVE: To evaluate the safety and efficacy of peripheral vitrectomy under air in rhegmatogenous retinal detachment (RRD). PATIENTS AND METHODS: Consecutive patients who underwent 23-gauge pars plana vitrectomy for RRD were included. After removal of core vitreous and drainage of subretinal fluid, peripheral vitreous was removed under air infusion without scleral indentation. Silicone oil or C3F8 gas was used as tamponade. RESULTS: Forty-five eyes of 45 patients were evaluated retrospectively...
January 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
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