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https://www.readbyqxmd.com/read/28526754/oxygenation-and-adenosine-deaminase-support-growth-and-proliferation-of-ex-vivo-cultured-drosophila-wing-imaginal-discs
#1
Katrin Strassburger, Franziska K Lorbeer, Marilena Lutz, Fabian Graf, Michael Boutros, Aurelio A Teleman
The Drosophila wing imaginal disc has been an important model system over the past decades for discovering novel biology related to development, signaling, and epithelial morphogenesis. Novel experimental approaches would be enabled by a culturing setup allowing ex vivo cultures of wing discs. Current setups, however, are not able to sustain both growth and cell-cycle progression of wing discs ex vivo. We discover here a setup requiring both oxygenation of the tissue and adenosine deaminase activity in the medium, which supports both growth and proliferation of wing discs for 9 hours...
May 19, 2017: Development
https://www.readbyqxmd.com/read/28526668/north-american-public-opinion-survey-on-the-acceptability-of-crowdsourcing-basic-life-support-for-out-of-hospital-cardiac-arrest-with-the-pulsepoint-mobile-phone-app
#2
Katie N Dainty, Haris Vaid, Steven C Brooks
BACKGROUND: The PulsePoint Respond app is a novel system that can be implemented in emergency dispatch centers to crowdsource basic life support (BLS) for patients with cardiac arrest and facilitate bystander cardiopulmonary resuscitation (CPR) and automated external defibrillator use while first responders are en route. OBJECTIVE: The aim of this study was to conduct a North American survey to evaluate the public perception of the above-mentioned strategy, including acceptability and willingness to respond to alerts...
May 17, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28525336/accuracy-of-real-time-shear-wave-elastography-in-the-assessment-of-normal-liver-tissue-in-the-guinea-pig-cavia-porcellus
#3
K Glińska-Suchocka, K Kubiak, J Spużak, M Jankowski, P Borusewicz
Shear wave elastography is a novel technique enabling real-time measurement of the elasticity of liver tissue. The color map is superimposed on the classic ultrasound image of the assessed tissue, which enables a precise evaluation of the stiffness of the liver tissue. The aim of the study was to assess the stiffness of normal liver tissue in the guinea pig using shear wave elastography. The study was carried out on 36 guinea pigs using the SuperSonic Imagine Aixplorer scanner, and a 1 to 6 MH convex SC6-1 transducer...
March 28, 2017: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/28524143/-features-of-psycho-emotional-state-of-patients-with-central-serous-chorioretinopathy
#4
A A Shchuko, T N Yureva, A N Zlobina
AIM: to investigate peculiarities of psycho-emotional reactions in patients with central serous chorioretinopathy (CSCR). MATERIAL AND METHODS: The study involved 35 patients with CSCR (mean age of 47.7±8.5 years) and 26 volunteers without visual impairment (mean age of 35.8±4.5 years). Their psycho-emotional state was studied using the SCL-90-R questionnaire (the severity of psychopathological symptomatology), TOBOL method (the type of attitude to the disease), Ways of Coping Questionnaire (WCQ) (strategies for controlling behavior), Spielberger-Hanin method (the level of anxiety), and the VFQ-25 questionnaire (quality of life)...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28518091/long-term-live-imaging-of-drosophila-eye-disc
#5
Chia-Kang Tsao, Hui-Yu Ku, Y Henry Sun
Live imaging provides the ability to continuously track dynamic cellular and developmental processes in real time. Drosophila larval imaginal discs have been used to study many biological processes, such as cell proliferation, differentiation, growth, migration, apoptosis, competition, cell-cell signaling, and compartmental boundary formation. However, methods for the long-term ex vivo culture and live imaging of the imaginal discs have not been satisfactory, despite many efforts. Recently, we developed a method for the long-term ex vivo culture and live imaging of imaginal discs for up to 18 h...
May 6, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28513366/nurses-wearing-body-cams
#6
J Kissoon
This is inconceivable in mental health settings. Can you imagine an acutely unwell individual with paranoid and psychotic symptoms being seen by a nurse wearing a body cam? Not to mention issues around confidentiality.
May 17, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28512185/cap-n-collar-promotes-tissue-regeneration-by-regulating-ros-and-jnk-signaling-in-the-drosophila-wing-imaginal-disc
#7
Amanda R Brock, Mabel Seto, Rachel K Smith-Bolton
Regeneration is a complex process that requires an organism to recognize and repair tissue damage, as well as grow and pattern new tissue. Here we describe a genetic screen to identify novel regulators of regeneration. We ablated the Drosophila melanogaster larval wing primordium by inducing apoptosis in a spatially and temporally controlled manner and allowed the tissue to regenerate and repattern. To identify genes that regulate regeneration, we carried out a dominant modifier screen by assessing the amount and quality of regeneration in adult wings heterozygous for isogenic deficiencies...
May 16, 2017: Genetics
https://www.readbyqxmd.com/read/28509604/moving-forth-imagining-physiotherapy-education-differently
#8
Sarah Barradell
Contemporary and future physiotherapists are, and will be, presented with challenges different to their forebears. Yet, physiotherapy tends to remain tied to historical ways of seeing the world: these are passed down to generations of physiotherapy graduates. These historical perspectives privilege particular knowledge and skills so that students gain competency for graduation. However, contemporary practice is inherently more complex than the focus on knowledge and skills would have us believe. Professional life requires students to develop the capability to deal with uncertain and diverse futures...
May 16, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28509418/review-article-sirenomelia-a-multi-systemic-polytopic-field-defect-with-ongoing-controversies
#9
REVIEW
Lucas L Boer, Eva Morava, Willemijn M Klein, Annelieke N Schepens-Franke, Roelof Jan Oostra
The most impressive phenotypic appearance of sirenomelia is the presence of a 180°-rotated, axially positioned, single lower limb. Associated gastrointestinal and genitourinary anomalies are almost always present. This rare anomaly is still the subject of ongoing controversies concerning its nosology, pathogenesis, and possible genetic etiology. Sirenomelia can be part of a syndromic continuum, overlapping with other complex conditions including caudal dysgenesis and VATER/VACTERL/VACTERL-H associations, which could all be part of a heterogeneous spectrum, and originate from an early defect in blastogenesis...
May 16, 2017: Birth Defects Res
https://www.readbyqxmd.com/read/28508382/think-fast-rapid-assessment-of-the-effects-of-episodic-future-thinking-on-delay-discounting-in-overweight-obese-participants
#10
Jeffrey S Stein, Yan Yan Sze, Liqa Athamneh, Mikhail N Koffarnus, Leonard H Epstein, Warren K Bickel
Accumulating laboratory-based evidence indicates that reducing delay discounting (devaluation of delayed outcomes) with the use of episodic future thinking (EFT; mental simulation of future events) improves dietary decision-making and other maladaptive behaviors. Recent work has adapted EFT for use in the natural environment to aid in dietary and weight control by engaging participants in EFT repeatedly throughout the day. These efforts may benefit from minimizing the amount of time required for measurement and implementation of EFT...
May 15, 2017: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28505956/regression-of-lumbar-disc-herniation-by-physiotherapy-does-non-surgical-spinal-decompression-therapy-make-difference-double-blind-randomized-controlled-trial
#11
Aynur Demirel, Mehmet Yorubulut, Nevin Ergun
BACKGROUND AND OBJECTIVES: The aim of the study determining whether or not Non-invasive Spinal Decompression Therapy (NSDT) was effective in resorption of herniation, increasing disc height in patients with lumbar disc herniation (LHNP). METHODS: A total of twenty patients diagnosed as LHNP and suffering from pain at least 8 weeks were enrolled to the study. Patients were allocated in study (SG) and control groups (CG) randomly. Both groups received combination of electrotherapy, deep friction massage and stabilization exercise for fifteen session...
May 5, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28504898/dissociable-contributions-of-imagination-and-willpower-to-the-malleability-of-human-patience
#12
Adrianna C Jenkins, Ming Hsu
The ability to exercise patience is important for human functioning. Although it is known that patience can be promoted by using top-down control, or willpower, to override impatient impulses, patience is also malleable-in particular, susceptible to framing effects-in ways that are difficult to explain using willpower alone. So far, the mechanisms underlying framing effects on patience have been elusive. We investigated the role of imagination in these effects. In a behavioral experiment (Experiment 1), a classic framing manipulation (sequence framing) increased self-reported and independently coded imagination during intertemporal choice...
May 1, 2017: Psychological Science
https://www.readbyqxmd.com/read/28504337/archaic-man-meets-a-marvellous-automaton-posthumanism-social-robots-archetypes
#13
Raya Jones
Posthumanism is associated with critical explorations of how new technologies are rewriting our understanding of what it means to be human and how they might alter human existence itself. Intersections with analytical psychology vary depending on which technologies are held in focus. Social robotics promises to populate everyday settings with entities that have populated the imagination for millennia. A legend of A Marvellous Automaton appears as early as 350 B.C. in a book of Taoist teachings, and is joined by ancient and medieval legends of manmade humanoids coming to life, as well as the familiar robots of modern science fiction...
June 2017: Journal of Analytical Psychology
https://www.readbyqxmd.com/read/28503872/the-effect-of-brief-digital-interventions-on-attitudes-to-intellectual-disability-results-from-a-pilot-study
#14
Natalie Lindau, Tara Amin, Amy Zambon, Katrina Scior
BACKGROUND: Evidence on the effects of contact and education based interventions on attitudes is limited in the intellectual disability field. This study compared the effects of brief interventions with different education, indirect and imagined contact components on lay people's attitudes. MATERIALS AND METHODS: 401 adult participants were randomised to six digital brief interventions consisting of different combinations of education, indirect and imagined contact...
May 15, 2017: Journal of Applied Research in Intellectual Disabilities: JARID
https://www.readbyqxmd.com/read/28502613/generation-of-a-targeted-expression-system-for-branchless-and-characterization-of-novel-cellular-expression-patterns-of-the-gene-in-drosophila
#15
Lijuan Du, Amy Zhou, Akshay Patel, Mishal Rao, Kelsey Anderson, Sougata Roy
Fibroblast growth factors (FGF) are essential signaling proteins that regulate diverse cellular functions in developmental and metabolic processes. In Drosophila, the FGF homolog, branchless (bnl) is expressed in a dynamic and spatiotemporally restricted pattern to induce branching morphogenesis of the trachea, which expresses the Bnl-receptor, breathless (btl). Here we have developed a new strategy to determine bnl- expressing cells and study their interactions with the btl-expressing cells in the range of tissue patterning during Drosophila development...
May 11, 2017: Developmental Biology
https://www.readbyqxmd.com/read/28502021/the-visual-and-haptic-contributions-to-hand-perception
#16
Lara A Coelho, Claudia Lr Gonzalez
Previous research has found that the perception of our hands is distorted. The characteristics of this distortion are an overestimation of hand width and an underestimation of finger length. The present study examined the role that different sensory modalities (vision and/or haptics) play in the perception of our hands. Participants pointed to their concealed hand in one of three groups: Vision+Haptics, Vision-only, or Haptics-only. Participants in the Vision+Haptics group had vision (non-informative) of the experimental setup and of the pointing hand, but no vision of the hand being estimated...
May 13, 2017: Psychological Research
https://www.readbyqxmd.com/read/28501637/serial-endosymbiosis-or-singular-event-at-the-origin-of-eukaryotes
#17
Nick Lane
'On the Origin of Mitosing Cells' heralded a new way of seeing cellular evolution, with symbiosis at its heart. Lynn Margulis (then Sagan) marshalled an impressive array of evidence for endosymbiosis, from cell biology to atmospheric chemistry and Earth history. Despite her emphasis on symbiosis, she saw plenty of evidence for gradualism in eukaryotic evolution, with multiple origins of mitosis and sex, repeated acquisitions of plastids, and putative evolutionary intermediates throughout the microbial world...
May 10, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/28500675/counterfactual-plausibility-and-comparative-similarity
#18
Matthew L Stanley, Gregory W Stewart, Felipe De Brigard
Counterfactual thinking involves imagining hypothetical alternatives to reality. Philosopher David Lewis (1973, 1979) argued that people estimate the subjective plausibility that a counterfactual event might have occurred by comparing an imagined possible world in which the counterfactual statement is true against the current, actual world in which the counterfactual statement is false. Accordingly, counterfactuals considered to be true in possible worlds comparatively more similar to ours are judged as more plausible than counterfactuals deemed true in possible worlds comparatively less similar...
May 2017: Cognitive Science
https://www.readbyqxmd.com/read/28500361/-live-animals-and-staged-nature-drawing-and-photography-in-german-popular-zoology-between-1860-and-1910
#19
Alexander Gall
It is the central thesis of this paper that the "biological perspective" (Lynn Nyhart) typical for Germany, with its interest in living animals, not only influenced natural history practices in many ways during the second half of the 19th century, rather also shaped the illustrations of popular zoology publications, as for example those in Brehms Thierleben. The illustrators of this period preferred to use live animals as models, which they studied in zoos. These animals were often depicted in their "natural" habitats...
May 12, 2017: NTM
https://www.readbyqxmd.com/read/28499558/influence-of-response-bias-and-internal-external-source-on-lateral-posterior-parietal-successful-retrieval-activity
#20
Danielle R King, Michael B Miller
In studies of recognition memory, regions of the lateral posterior parietal cortex exhibit greater activity (as indexed by the fMRI BOLD signal) during correct recognition of "old" (studied) items than correct rejection of "new" (unstudied) items. This effect appears to be source-sensitive, with greater activity associated with recognition of perceived than imagined events. Parietal successful retrieval activity also varies with response bias, or the tendency to be conservative about making "old" judgments...
April 15, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
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