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https://www.readbyqxmd.com/read/28492787/validation-of-german-aortic-valve-score-in-a-multi-surgeon-single-center
#1
Mehmet Kalender, Ahmet Nihat Baysal, Okay Guven Karaca, Kamil Boyacioglu, Nihan Kayalar
OBJECTIVE: Risk assessment for operative mortality is mandatory for all cardiac operations. For some operation types such as aortic valve repair, EuroSCORE II overestimates the mortality rate and a new scoring system (German AV score) has been developed for a more accurate assessment of operative risk. In this study, we aimed to validate German Aortic Valve Score in our clinic in patients undergoing isolated aortic valve replacement. METHODS: A total of 35 patients who underwent isolated open aortic valve replacement between 2010 and 2013 were included...
March 2017: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28468170/might-trauma-be-a-triggering-factor-for-craniofacial-fibrous-dysplasia
#2
Mehmet Onur Yüksel, Mehmet Sabri Gürbüz, Hilmi Onder Okay, Mehmet Esref Kabalar
Fibrous dysplasia (FD) is a rare, benign disease of unclear etiology where normal bone is replaced with abnormal fibrous and weak osseous tissue. Any bone of the skeleton might be involved but skull is one of the most commonly affected sites. Fibrous dysplasia is known to be caused by a genetic mutation leading to inappropriate proliferation and differentiation of osteoblastic cells. However; it is not known whether any triggering factor exists which might contribute to this genetic mutation. The authors postulated that trauma might be a triggering factor for this disease...
May 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28454059/outcome-focused-judgements-of-moral-dilemmas-in-schizophrenia
#3
Jonathan McGuire, Martin Brüne, Robyn Langdon
Previous research on moral judgement in healthy adults suggests a complex interplay of automatic, emotional and deliberative processing. We aimed to advance understanding of these processes by examining moral judgement in individuals with schizophrenia, a population characterised by social-cognitive deficits and interpersonal difficulties. Forty-five patients with schizophrenia and 27 healthy controls judged high-conflict moral dilemmas in response to 3rd-person (i.e. "Is it morally okay to [perform X]?") and 1st-person (i...
April 25, 2017: Consciousness and Cognition
https://www.readbyqxmd.com/read/28436736/are-you-okay-to-drive-commuting-behavior-and-blood-alcohol-concentrations-amongst-restaurant-diners
#4
B Scott-Parker, L Stokes, S Panaho, M Cawkwell, J Caldwell
Objective Drink driving is widely recognised as a major road safety problem. In Australia, health promotion messages encourage monitoring the number of standard drinks consumed prior to driving. The pilot research aimed to investigate commuting behaviour and blood alcohol concentration (BAC) of diners, including intended-drivers, at Sunshine Coast restaurants. Methods Five hundred and forty-four diners (n = 260 males) consented to participate in a brief interview and to use a breathalyser device to measure their BAC...
February 25, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28434622/young-and-thriving-is-okay-young-and-not-thriving-is-not
#5
EDITORIAL
Timothy J Pirolli, Robert D B Jaquiss
No abstract text is available yet for this article.
April 5, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28301693/the-clue
#6
Tyler Tate
As I stood outside of Carlos's room, I felt caught on the horns of a dilemma. It seemed impossible to truly "be there" for Carlos without sacrificing my other intern duties. This tension pervaded much of my residency training, as I often found myself spending more time completing chart notes, answering pages, and giving sign out than I did at the bedside with my patients. I knew I had a duty to "do my job"-I could not let my team down. But what about my duty to Carlos, a duty to act on my intuition and try to "get to the bottom" of his illness, if that was even possible? And what about my thirteen other patients? Wasn't I was their doctor as well? I have spent countless hours studying the ethical frameworks for medical rationing...
March 2017: Hastings Center Report
https://www.readbyqxmd.com/read/28294936/examining-the-feasibility-of-implementing-behavioural-economics-strategies-that-encourage-home-dinner-vegetable-intake-among-low-income-children
#7
Tashara M Leak, Alison Swenson, Aaron Rendahl, Zata Vickers, Elton Mykerezi, Joseph P Redden, Traci Mann, Marla Reicks
OBJECTIVE: To examine the feasibility of implementing nine behavioural economics-informed strategies, or 'nudges', that aimed to encourage home dinner vegetable intake among low-income children. DESIGN: Caregivers were assigned six of nine strategies and implemented one new strategy per week (i.e. 6 weeks) during three dinner meals. Caregivers recorded child dinner vegetable intake on the nights of strategy implementation and rated the level of difficulty for assigned strategies...
March 15, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28262908/relationship-between-myocardial-performance-index-and-severity-of-coronary-artery-disease-in-patients-with-non-st-segment-elevation-acute-coronary-syndrome
#8
Okay Abaci, Cuneyt Kocas, Veysel Oktay, Sukru Arslan, Yusuf Turkmen, Cem Bostan, Ugur Coskun, Ahmet Yildiz, Murat Ersanli
OBJECTIVES: We aimed to investigate the relationship between myocardial performance index (MPI) and severity of coronary artery disease, as assessed by the Gensini score (GS), in patients with non-ST-segment elevation myocardial infarction (NSTEMI). METHODS: Ninety patients with an initial diagnosis of NSTEMI were enrolled in our study. They were divided into tertiles according to the GS: low GS < 19; mid GS > 19 and ≤ 96; and high GS > 96. RESULTS: The low-, mid- and high-GS groups included 24, 38 and 28 patients, respectively...
January 2017: Cardiovascular Journal of Africa
https://www.readbyqxmd.com/read/28208126/the-prosody-of-the-czech-discourse-marker-jasn%C3%A4-an-analysis-of-forms-and-functions
#9
Jan Volin, Lenka Weingartová, Oliver Niebuhr
Words like yeah, okay and (al)right are fairly unspecific in their lexical semantics, and not least for this reason there is a general tendency for them to occur with highly varied and expressive prosodic patterns across languages. Here we examine in depth the prosodic forms that express eight pragmatic functions of the Czech discourse marker jasně, including resignation, reassurance, surprise, indifference or impatience. Using a collection of 172 tokens from a corpus of scripted dialogues by 30 native speakers, we performed acoustic analyses, applied classification algorithms and solicited judgments from native listeners in a perceptual experiment...
2016: Phonetica
https://www.readbyqxmd.com/read/28176926/parental-opinions-regarding-an-opt-out-consent-process-for-inpatient-pediatric-prospective-observational-research-in-the-us
#10
Danielle M Fernandes, Allison P Roland, Marilyn C Morris
OBJECTIVE: To explore parental opinions regarding opt-out consent for inpatient pediatric prospective observational research in the US. STUDY DESIGN: A series of handouts describing hypothetical observational research studies with opt-out consent were reviewed by parents of hospitalized children. A verbal survey explored parental opinions about the proposed consent process. RESULTS: A total of 166 parents reviewed the handout and completed the survey...
2017: Pragmatic and Observational Research
https://www.readbyqxmd.com/read/28148254/building-trust-and-rapport-early-in-the-new-doctor-patient-relationship-a-longitudinal-qualitative-study
#11
Bich N Dang, Robert A Westbrook, Sarah M Njue, Thomas P Giordano
BACKGROUND: New patients are a particularly vulnerable population because they are at high risk of missing a subsequent visit or dropping out of care completely. However, few data exist on what new patients value in the beginning of a relationship with a new provider. Persons with HIV infection may be an ideal population to study the drivers of a positive initial patient-provider relationship, as it is a chronic and serious condition that requires a reliable, ongoing relationship with a provider...
February 2, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28143535/living-with-dementia-in-a-nursing-home-as-described-by-persons-with-dementia-a-phenomenological-hermeneutic-study
#12
Marit Mjørud, Knut Engedal, Janne Røsvik, Marit Kirkevold
BACKGROUND: Persons with dementia have described life in nursing home as difficult and lonely. Persons with dementia often reside in nursing homes for several years; therefore, knowledge is needed about how quality of life is affected in the nursing-home setting in order to be able to provide the best possible care. The aim of this study was to investigate the personal experience of living in a nursing home over time from the perspective of the person with dementia and to learn what makes life better or worse in the nursing home...
January 31, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28118187/might-trauma-be-a-triggering-factor-for-craniofacial-fibrous-dysplasia
#13
Mehmet Onur Yüksel, Mehmet Sabri Gürbüz, Hilmi Onder Okay, Mehmet Esref Kabalar
Fibrous dysplasia (FD) is a rare, benign disease of unclear etiology where normal bone is replaced with abnormal fibrous and weak osseous tissue. Any bone of the skeleton might be involved but skull is one of the most commonly affected sites. Fibrous dysplasia is known to be caused by a genetic mutation leading to inappropriate proliferation and differentiation of osteoblastic cells. However; it is not known whether any triggering factor exists which might contribute to this genetic mutation. The authors postulated that trauma might be a triggering factor for this disease...
January 23, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28095352/the-relationship-of-rel-proto-oncogene-to-pathobiology-and-chemoresistance-in-follicular-and-transformed-follicular-lymphoma
#14
Xiaozhou Hu, Esra Baytak, Jinnan Li, Burcu Akman, Kaan Okay, Genfu Hu, Anna Scuto, Wenyan Zhang, Can Küçük
Follicular lymphoma (FL) is a common type of indolent lymphoma that occasionally transforms to more aggressive B-cell lymphomas. These transformed follicular lymphomas (tFL) are often associated with chemoresistance whose mechanisms are currently unknown. REL, a proto-oncogene located on frequently amplified 2p16.1-p15 locus, promotes tumorigenesis in many cancer types through deregulation of the NF-κB pathway; however, its role in FL pathobiology or chemoresistance has not been addressed. Here, we evaluated REL gene copy number by q-PCR on FFPE FL tumor samples, and observed REL amplification in 30...
March 2017: Leukemia Research
https://www.readbyqxmd.com/read/28092684/biallelic-mutations-in-the-3-exonuclease-toe1-cause-pontocerebellar-hypoplasia-and-uncover-a-role-in-snrna-processing
#15
Rea M Lardelli, Ashleigh E Schaffer, Veerle R C Eggens, Maha S Zaki, Stephanie Grainger, Shashank Sathe, Eric L Van Nostrand, Zinayida Schlachetzki, Basak Rosti, Naiara Akizu, Eric Scott, Jennifer L Silhavy, Laura Dean Heckman, Rasim Ozgur Rosti, Esra Dikoglu, Anne Gregor, Alicia Guemez-Gamboa, Damir Musaev, Rohit Mande, Ari Widjaja, Tim L Shaw, Sebastian Markmiller, Isaac Marin-Valencia, Justin H Davies, Linda de Meirleir, Hulya Kayserili, Umut Altunoglu, Mary Louise Freckmann, Linda Warwick, David Chitayat, Susan Blaser, Ahmet Okay Çağlayan, Kaya Bilguvar, Huseyin Per, Christina Fagerberg, Henrik T Christesen, Maria Kibaek, Kimberly A Aldinger, David Manchester, Naomichi Matsumoto, Kazuhiro Muramatsu, Hirotomo Saitsu, Masaaki Shiina, Kazuhiro Ogata, Nicola Foulds, William B Dobyns, Neil C Chi, David Traver, Luigina Spaccini, Stefania Maria Bova, Stacey B Gabriel, Murat Gunel, Enza Maria Valente, Marie-Cecile Nassogne, Eric J Bennett, Gene W Yeo, Frank Baas, Jens Lykke-Andersen, Joseph G Gleeson
Deadenylases are best known for degrading the poly(A) tail during mRNA decay. The deadenylase family has expanded throughout evolution and, in mammals, consists of 12 Mg(2+)-dependent 3'-end RNases with substrate specificity that is mostly unknown. Pontocerebellar hypoplasia type 7 (PCH7) is a unique recessive syndrome characterized by neurodegeneration and ambiguous genitalia. We studied 12 human families with PCH7, uncovering biallelic, loss-of-function mutations in TOE1, which encodes an unconventional deadenylase...
March 2017: Nature Genetics
https://www.readbyqxmd.com/read/28076996/a-serious-case-of-anthrax-associated-with-compartment-syndrome
#16
Seyran Kılınç, Mehmet Vakıf Keskinbıçkı, Murat Şengül, Semra Nergiz, Abdurrahman Örtücü, Okay Bulut
Compartment syndrome linked to skin anthrax is a rare complication that may develop and it should be noted that the disease may progress in spite of medical drug treatment. Our case was a farmer who was exposed after slaughtering a dead animal, a time delay for treatment hided this history and then developed compartment syndrome. In anthrax cases with delayed treatment and aggressive progression, circulation in the extremities should be carefully noted. We believe that the cases with compartment syndrome progressing in spite of medical drug treatment may be assessed for fasciotomy as a treatment approach...
January 11, 2017: Cutaneous and Ocular Toxicology
https://www.readbyqxmd.com/read/28074454/obturator-hernia-should-be-considered-in-the-differential-diagnosis-of-hip-and-knee-pain
#17
Ahmet Korkut Belli, Gündüz Memiş, Özcan Dere, Ulaş Koşan, Okay Nazlı
Obturator hernia is a rare disease usually occurring in debilitated elderly women. Pain radiating down the medial thigh and knee (Howship-Romberg sign) is a specific sign of the disease. Presently described is a case of obturator hernia in a 73-year-old female patient who presented with severe left hip pain radiating down the medial thigh and knee, nausea, and loss of appetite. Initially, vertebral disc herniation was thought to be cause, but abdomino-pelvic computed tomography scan revealed left strangulated obturator hernia...
November 2016: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/28028952/mastalgia-due-to-degenerative-changes-of-the-spine
#18
Okay Pirti, Aziz M Barlas, Serdar Kuru, Selim Temel, Mustafa K Urhan, Kemal Kismet, Adnan Hasanoglu, Osman Guler
BACKGROUND: Mastalgia is a common and enigmatic condition; the cause and optimal treatment are still inadequately defined. Cervical radiculopathy, which is the result of cervical nerve root pathology often caused by spaceoccupying lesions such as cervical disc herniation, spondylosis, or osteophytosis, is frequently encountered in physical therapy. OBJECTIVES: The aim of the study was to evaluate the incidence of vertebral pathologies in patients with non-cyclic mastalgia and the efficacy of conservative treatment of these pathologies on relieving breast pain...
September 2016: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/27941457/is-it-okay-to-cry-with-patients
#19
Mary T Sweat
No abstract text is available yet for this article.
January 2017: Journal of Christian Nursing: a Quarterly Publication of Nurses Christian Fellowship
https://www.readbyqxmd.com/read/27919704/global-transcriptome-analysis-of-halolamina-sp-to-decipher-the-salt-tolerance-in-extremely-halophilic-archaea
#20
Aslıhan Kurt-Kızıldoğan, Büşra Abanoz, Sezer Okay
Extremely halophilic archaea survive in the hypersaline environments such as salt lakes or salt mines. Therefore, these microorganisms are good sources to investigate the molecular mechanisms underlying the tolerance to high salt concentrations. In this study, a global transcriptome analysis was conducted in an extremely halophilic archaeon, Halolamina sp. YKT1, isolated from a salt mine in Turkey. A comparative RNA-seq analysis was performed using YKT1 isolate grown either at 2.7M NaCl or 5.5M NaCl concentrations...
February 15, 2017: Gene
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