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https://www.readbyqxmd.com/read/28648467/differentiating-could-from-should-developmental-changes-in-modal-cognition
#1
Andrew Shtulman, Jonathan Phillips
Young children have difficulty in distinguishing events that violate physical laws (impossible events) from those that violate mere physical regularities (improbable events). They judge both as "impossible." Young children also have difficulty in distinguishing events that violate moral laws (immoral events) from events that violate mere social regularities (unconventional events). They judge both as "wrong." In this set of studies, we explored the possibility that both difficulties arise from a more general deficit in modal cognition, or the way in which children represent and reason about possibilities...
June 22, 2017: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/28630369/alpk3-gene-mutation-in-a-patient-with-congenital-cardiomyopathy-and-dysmorphic-features
#2
Ahmet Okay Cağlayan, Rabia Gonul Sezer, Hande Kaymakcalan, Ege Ulgen, Taner Yavuz, Jacob F Baranoski, Abdulkadir Bozaykut, Akdes Serin Harmanci, Yalim Yalcin, Mark W Youngblood, Katsuhito Yasuno, Kaya Bilguvar, Murat Gunel
Primary cardiomyopathy is one of the most common inherited cardiac diseases and harbors significant phenotypic and genetic heterogeneity. Because of this, genetic testing has become standard in treatment of this disease group. Indeed, in recent years, next-generation DNA sequencing has found broad applications in medicine, both as a routine diagnostic tool for genetic disorders and also as a high-throughput discovery tool for identifying novel disease causing genes. We describe a male infant with primary dilated cardiomyopathy that was diagnosed using intrauterine echocardiography, and found to progress to hypertrophic cardiomyopathy after birth...
June 19, 2017: Cold Spring Harbor Molecular Case Studies
https://www.readbyqxmd.com/read/28599999/-tell-me-exactly-what-s-happened-when-linguistic-choices-affect-the-efficiency-of-emergency-calls-for-cardiac-arrest
#3
Marine Riou, Stephen Ball, Teresa A Williams, Austin Whiteside, Kay L O'Halloran, Janet Bray, Gavin D Perkins, Karen Smith, Peter Cameron, Daniel M Fatovich, Madoka Inoue, Paul Bailey, Deon Brink, Judith Finn
BACKGROUND: Clear and efficient communication between emergency caller and call-taker is crucial to timely ambulance dispatch. We aimed to explore the impact of linguistic variation in the delivery of the prompt "okay, tell me exactly what happened" on the way callers describe the emergency in the Medical Priority Dispatch System(®). METHODS: We analysed 188 emergency calls for cases of paramedic-confirmed out-of-hospital cardiac arrest. We investigated the linguistic features of the prompt "okay, tell me exactly what happened" in relation to the format (report vs...
June 12, 2017: Resuscitation
https://www.readbyqxmd.com/read/28598542/overexpression-of-minichromosome-maintenance-protein-10-in-medulloblastoma-and-its-clinical-implications
#4
Daniel Senfter, Erdogan Pekcan Erkan, Erdener Özer, Gerhard Jungwirth, Sibylle Madlener, Marcel Kool, Thomas Ströbel, Nurten Saydam, Okay Saydam
BACKGROUND: Overexpression of minichromosome maintenance (MCM) proteins 2, 3, and 7 is associated with migration and invasion in medulloblastoma (MB). However, expression profiling of all prereplication complex (pre-RC) has not been addressed in MBs. PROCEDURE: We performed mRNA expression profiling of a large set of pre-RC elements in cell lines and tumor tissues of MB. RNAi technology was employed for functional studies in MB cell lines. RESULTS: Our data showed that most of the pre-RC components are significantly overexpressed in MB...
June 9, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28582331/short-segment-spinal-instrumentation-in-early-onset-scoliosis-patients-treated-with-magnetically-controlled-growing-rods-surgical-technique-and-mid-short-term-outcomes
#5
Ahmed Majid Heydar, Serdar Şirazi, Erhan Okay, Murat Bezer
STUDY DESIGN: Prospective, a single institution, non-randomized study. OBJECTIVE: To evaluate the safety and effectivity of short-segment instrumentation in early onset scoliosis (EOS) patients treated by magnetic controlled growing rods (MCGR). SUMMERY OF BACKGROUND DATA: Despite the common use of conventional growing rods and the recent popularity of MCGR in the treatment of progressive EOS, distal instrumented vertebra and number of the spanned levels are not standardized...
June 2, 2017: Spine
https://www.readbyqxmd.com/read/28574116/the-influence-of-acetabular-morphology-on-prediction-of-proximal-femur-fractures-types-in-an-elderly-population
#6
Abbas Tokyay, Melih Güven, Mehmet E Encan, Erhan Okay, Ozgur Akbaba
INTRODUCTION: The role of proximal femur morphology to the development of certain proximal femur fracture types both femoral neck and trochanteric fractures has been observed. However, the relavance of acetabular morphology to the development of proximal femur fractures is not extensively questioned. Therefore the aim of the study was to determine whether there is a correlation between acetabular morphology and pathogenesis of 2 different hip fracture types after low energy trauma. METHOD: This retrospective study includes 60 cases (41 women, 19 men) with a proximal femoral fracture after a low energy trauma between July 2012 and December 2014...
May 23, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/28573993/delayed-follow-up-in-patients-with-diabetic-retinopathy-in-south-india-social-factors-and-impact-on-disease-progression
#7
Natrajan Vengadesan, Meleha Ahmad, Manavi D Sindal, Sabyasachi Sengupta
PURPOSE: To identify social factors associated with delayed follow-up in South Indian patients with diabetic retinopathy (DR) and to study DR progression during the delayed follow-up period. MATERIALS AND METHODS: In this cross-sectional study, 500 consecutive patients with DR returning after greater than twice the advised follow-up period were identified from a tertiary referral center in South India. A previously validated 19-item questionnaire was administered to study patients to assess causes for the follow-up delay...
May 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28492787/validation-of-german-aortic-valve-score-in-a-multi-surgeon-single-center
#8
Mehmet Kalender, Ahmet Nihat Baysal, Okay Guven Karaca, Kamil Boyacioglu, Nihan Kayalar
OBJECTIVE: Risk assessment for operative mortality is mandatory for all cardiac operations. For some operation types such as aortic valve repair, EuroSCORE II overestimates the mortality rate and a new scoring system (German AV score) has been developed for a more accurate assessment of operative risk. In this study, we aimed to validate German Aortic Valve Score in our clinic in patients undergoing isolated aortic valve replacement. METHODS: A total of 35 patients who underwent isolated open aortic valve replacement between 2010 and 2013 were included...
March 2017: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28468170/might-trauma-be-a-triggering-factor-for-craniofacial-fibrous-dysplasia
#9
Mehmet Onur Yüksel, Mehmet Sabri Gürbüz, Hilmi Onder Okay, Mehmet Esref Kabalar
Fibrous dysplasia (FD) is a rare, benign disease of unclear etiology where normal bone is replaced with abnormal fibrous and weak osseous tissue. Any bone of the skeleton might be involved but skull is one of the most commonly affected sites. Fibrous dysplasia is known to be caused by a genetic mutation leading to inappropriate proliferation and differentiation of osteoblastic cells. However; it is not known whether any triggering factor exists which might contribute to this genetic mutation. The authors postulated that trauma might be a triggering factor for this disease...
May 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28454059/outcome-focused-judgements-of-moral-dilemmas-in-schizophrenia
#10
Jonathan McGuire, Martin Brüne, Robyn Langdon
Previous research on moral judgement in healthy adults suggests a complex interplay of automatic, emotional and deliberative processing. We aimed to advance understanding of these processes by examining moral judgement in individuals with schizophrenia, a population characterised by social-cognitive deficits and interpersonal difficulties. Forty-five patients with schizophrenia and 27 healthy controls judged high-conflict moral dilemmas in response to 3rd-person (i.e. "Is it morally okay to [perform X]?") and 1st-person (i...
April 25, 2017: Consciousness and Cognition
https://www.readbyqxmd.com/read/28436736/are-you-okay-to-drive-commuting-behavior-and-blood-alcohol-concentrations-among-restaurant-diners
#11
Bridie Scott-Parker, Leanne Stokes, Shane Panaho, Megan Cawkwell, Jamie Caldwell
OBJECTIVE: Drink driving is widely recognized as a major road safety problem. In Australia, health promotion messages encourage monitoring the number of standard drinks consumed prior to driving. This pilot research aimed to investigate commuting behavior and blood alcohol concentration (BAC) of diners, including intended drivers, at Sunshine Coast restaurants. METHODS: Five hundred and forty-four diners (n = 260 males) consented to participate in a brief interview and to use a breathalyzer device to measure their BAC...
February 25, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28434622/young-and-thriving-is-okay-young-and-not-thriving-is-not
#12
EDITORIAL
Timothy J Pirolli, Robert D B Jaquiss
No abstract text is available yet for this article.
July 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28301693/the-clue
#13
Tyler Tate
As I stood outside of Carlos's room, I felt caught on the horns of a dilemma. It seemed impossible to truly "be there" for Carlos without sacrificing my other intern duties. This tension pervaded much of my residency training, as I often found myself spending more time completing chart notes, answering pages, and giving sign out than I did at the bedside with my patients. I knew I had a duty to "do my job"-I could not let my team down. But what about my duty to Carlos, a duty to act on my intuition and try to "get to the bottom" of his illness, if that was even possible? And what about my thirteen other patients? Wasn't I was their doctor as well? I have spent countless hours studying the ethical frameworks for medical rationing...
March 2017: Hastings Center Report
https://www.readbyqxmd.com/read/28294936/examining-the-feasibility-of-implementing-behavioural-economics-strategies-that-encourage-home-dinner-vegetable-intake-among-low-income-children
#14
Tashara M Leak, Alison Swenson, Aaron Rendahl, Zata Vickers, Elton Mykerezi, Joseph P Redden, Traci Mann, Marla Reicks
OBJECTIVE: To examine the feasibility of implementing nine behavioural economics-informed strategies, or 'nudges', that aimed to encourage home dinner vegetable intake among low-income children. DESIGN: Caregivers were assigned six of nine strategies and implemented one new strategy per week (i.e. 6 weeks) during three dinner meals. Caregivers recorded child dinner vegetable intake on the nights of strategy implementation and rated the level of difficulty for assigned strategies...
March 15, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28262908/relationship-between-myocardial-performance-index-and-severity-of-coronary-artery-disease-in-patients-with-non-st-segment-elevation-acute-coronary-syndrome
#15
Okay Abaci, Cuneyt Kocas, Veysel Oktay, Sukru Arslan, Yusuf Turkmen, Cem Bostan, Ugur Coskun, Ahmet Yildiz, Murat Ersanli
OBJECTIVES: We aimed to investigate the relationship between myocardial performance index (MPI) and severity of coronary artery disease, as assessed by the Gensini score (GS), in patients with non-ST-segment elevation myocardial infarction (NSTEMI). METHODS: Ninety patients with an initial diagnosis of NSTEMI were enrolled in our study. They were divided into tertiles according to the GS: low GS < 19; mid GS > 19 and ≤ 96; and high GS > 96. RESULTS: The low-, mid- and high-GS groups included 24, 38 and 28 patients, respectively...
January 2017: Cardiovascular Journal of Africa
https://www.readbyqxmd.com/read/28208126/the-prosody-of-the-czech-discourse-marker-jasn%C3%A4-an-analysis-of-forms-and-functions
#16
Jan Volin, Lenka Weingartová, Oliver Niebuhr
Words like yeah, okay and (al)right are fairly unspecific in their lexical semantics, and not least for this reason there is a general tendency for them to occur with highly varied and expressive prosodic patterns across languages. Here we examine in depth the prosodic forms that express eight pragmatic functions of the Czech discourse marker jasně, including resignation, reassurance, surprise, indifference or impatience. Using a collection of 172 tokens from a corpus of scripted dialogues by 30 native speakers, we performed acoustic analyses, applied classification algorithms and solicited judgments from native listeners in a perceptual experiment...
2016: Phonetica
https://www.readbyqxmd.com/read/28176926/parental-opinions-regarding-an-opt-out-consent-process-for-inpatient-pediatric-prospective-observational-research-in-the-us
#17
Danielle M Fernandes, Allison P Roland, Marilyn C Morris
OBJECTIVE: To explore parental opinions regarding opt-out consent for inpatient pediatric prospective observational research in the US. STUDY DESIGN: A series of handouts describing hypothetical observational research studies with opt-out consent were reviewed by parents of hospitalized children. A verbal survey explored parental opinions about the proposed consent process. RESULTS: A total of 166 parents reviewed the handout and completed the survey...
2017: Pragmatic and Observational Research
https://www.readbyqxmd.com/read/28148254/building-trust-and-rapport-early-in-the-new-doctor-patient-relationship-a-longitudinal-qualitative-study
#18
Bich N Dang, Robert A Westbrook, Sarah M Njue, Thomas P Giordano
BACKGROUND: New patients are a particularly vulnerable population because they are at high risk of missing a subsequent visit or dropping out of care completely. However, few data exist on what new patients value in the beginning of a relationship with a new provider. Persons with HIV infection may be an ideal population to study the drivers of a positive initial patient-provider relationship, as it is a chronic and serious condition that requires a reliable, ongoing relationship with a provider...
February 2, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28143535/living-with-dementia-in-a-nursing-home-as-described-by-persons-with-dementia-a-phenomenological-hermeneutic-study
#19
Marit Mjørud, Knut Engedal, Janne Røsvik, Marit Kirkevold
BACKGROUND: Persons with dementia have described life in nursing home as difficult and lonely. Persons with dementia often reside in nursing homes for several years; therefore, knowledge is needed about how quality of life is affected in the nursing-home setting in order to be able to provide the best possible care. The aim of this study was to investigate the personal experience of living in a nursing home over time from the perspective of the person with dementia and to learn what makes life better or worse in the nursing home...
January 31, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28118187/might-trauma-be-a-triggering-factor-for-craniofacial-fibrous-dysplasia
#20
Mehmet Onur Yüksel, Mehmet Sabri Gürbüz, Hilmi Onder Okay, Mehmet Esref Kabalar
Fibrous dysplasia (FD) is a rare, benign disease of unclear etiology where normal bone is replaced with abnormal fibrous and weak osseous tissue. Any bone of the skeleton might be involved but skull is one of the most commonly affected sites. Fibrous dysplasia is known to be caused by a genetic mutation leading to inappropriate proliferation and differentiation of osteoblastic cells. However; it is not known whether any triggering factor exists which might contribute to this genetic mutation. The authors postulated that trauma might be a triggering factor for this disease...
January 23, 2017: Journal of Craniofacial Surgery
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