Luca Nicosia, Luciano Mariano, Giuseppe Pellegrino, Federica Ferrari, Filippo Pesapane, Anna Carla Bozzini, Samuele Frassoni, Vincenzo Bagnardi, Davide Pupo, Giovanni Mazzarol, Elisa De Camilli, Claudia Sangalli, Massimo Venturini, Maria Pizzamiglio, Enrico Cassano
This retrospective study investigates the histopathological outcomes, upgrade rates, and disease-free survival (DFS) of high-risk breast lesions, including atypical ductal hyperplasia (ADH or DIN1b) and lobular in situ neoplasms (LIN), following Vacuum-Assisted Breast Biopsy (VABB) and surgical excision. The study addresses the challenge posed by these lesions due to their association with synchronous or adjacent Breast Cancer (BC) and increased future BC risk. The research, comprising 320 patients who underwent stereotactic VABB, focuses on 246 individuals with a diagnosis of ADH (120) or LIN (126) observed at follow-up...
February 19, 2024: Cancers