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https://www.readbyqxmd.com/read/27903326/characterizing-areas-of-potential-human-exposure-to-eastern-equine-encephalitis-virus-using-serological-and-clinical-data-from-horses
#1
J-P Rocheleau, J Arsenault, N H Ogden, L R Lindsay, M Drebot, P Michel
Eastern equine encephalitis (EEE) is a rare but severe emerging vector-borne disease affecting human and animal populations in the northeastern United States where it is endemic. Key knowledge gaps remain about the epidemiology of EEE virus (EEEV) in areas where its emergence has more recently been reported. In Eastern Canada, viral activity has been recorded in mosquitoes and horses throughout the 2000s but cases of EEEV in humans have not been reported so far. This study was designed to provide an assessment of possible EEEV human exposure by modelling environmental risk factors for EEEV in horses, identifying high-risk environments and mapping risk in the province of Quebec, Canada...
December 1, 2016: Epidemiology and Infection
https://www.readbyqxmd.com/read/27902824/trends-in-total-cholesterol-triglycerides-and-low-density-lipoprotein-in-us-adults-1999-2014
#2
Asher Rosinger, Margaret D Carroll, David Lacher, Cynthia Ogden
No abstract text is available yet for this article.
November 30, 2016: JAMA Cardiology
https://www.readbyqxmd.com/read/27895887/symmetry-lasts-longer-than-random-but-only-for-brief-presentations
#3
Ruth Ogden, Alexis D J Makin, Letizia Palumbo, Marco Bertamini
Previous research has shown that explicit emotional content or physical image properties (e.g., luminance, size, and numerosity) alter subjective duration. Palumbo recently demonstrated that the presence or absence of abstract reflectional symmetry also influenced subjective duration. Here, we explored this phenomenon further by varying the type of symmetry (reflection or rotation) and the objective duration of stimulus presentation (less or more than 1 second). Experiment 1 used a verbal estimation task in which participants estimated the presentation duration of reflection, rotation symmetry, or random square-field patterns...
November 2016: I-Perception
https://www.readbyqxmd.com/read/27884910/in-praise-of-the-vanishing-skill-of-watchful-waiting
#4
Jane Ogden
No abstract text is available yet for this article.
December 2016: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/27877097/preoperative-antibiotic-orders-protocol-initiated-pharmacist-order-entry
#5
Ben B Hyde, Richard K Ogden, Ron D Berger, Brad W VanBrimmer, Leslie M Stach
OBJECTIVE: To evaluate the antibiotic selection of preoperative orders before and after a pharmacist order entry protocol for patients with methicillin-resistant Staphylococcus aureus (MRSA) colonization. METHODS: A retrospective chart review of orthopedic surgery procedures on patients with MRSA colonization at a free-standing, academic pediatric hospital, between February 2010 and February 2012. RESULTS: Procedures that were performed pre protocol (n = 27) implementation had a 63% rate of appropriate antibiotic selection compared to 81% in the postprotocol group (n = 32; p = 0...
September 2016: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
https://www.readbyqxmd.com/read/27873038/the-importance-of-nonlinear-tissue-modelling-in-finite-element-simulations-of-infant-head-impacts
#6
Xiaogai Li, Håkan Sandler, Svein Kleiven
Despite recent efforts on the development of finite element (FE) head models of infants, a model capable of capturing head responses under various impact scenarios has not been reported. This is hypothesized partially attributed to the use of simplified linear elastic models for soft tissues of suture, scalp and dura. Orthotropic elastic constants are yet to be determined to incorporate the direction-specific material properties of infant cranial bone due to grain fibres radiating from the ossification centres...
November 21, 2016: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/27868162/the-choice-of-a-constitutive-formulation-for-modeling-limb-flexion-induced-deformations-and-stresses-in-the-human-femoropopliteal-arteries-of-different-ages
#7
Anastasia Desyatova, Jason MacTaggart, William Poulson, Paul Deegan, Carol Lomneth, Anjali Sandip, Alexey Kamenskiy
Open and endovascular treatments for peripheral arterial disease are notorious for high failure rates. Severe mechanical deformations experienced by the femoropopliteal artery (FPA) during limb flexion and interactions between the artery and repair materials play important roles and may contribute to poor clinical outcomes. Computational modeling can help optimize FPA repair, but these simulations heavily depend on the choice of constitutive model describing the arterial behavior. In this study finite element model of the FPA in the standing (straight) and gardening (acutely bent) postures was built using computed tomography data, longitudinal pre-stretch and biaxially determined mechanical properties...
November 21, 2016: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/27856870/toward-a-national-sustained-u-s-ecosystem-assessment
#8
Stephen T Jackson, Clifford S Duke, Stephanie E Hampton, Katharine L Jacobs, Lucas N Joppa, Karim-Aly S Kassam, Harold A Mooney, Laura A Ogden, Mary Ruckelshaus, Jason F Shogren
No abstract text is available yet for this article.
November 18, 2016: Science
https://www.readbyqxmd.com/read/27856316/estimation-of-the-binding-potential-bpnd-without-a-reference-region-or-blood-samples-for-brain-pet-studies
#9
Martin Schain, Francesca Zanderigo, J John Mann, R Todd Ogden
Binding potential (BPND) is a commonly used PET outcome measure because it can be estimated without blood sampling if a brain reference region (RR) devoid of the target of interest exists. For many radioligands, however, no RR exists, and the total distribution volume (VT), whose estimation requires arterial blood sampling, is normally considered as the outcome measure. Here, we present a method that allows calculation of BPND without requiring either blood samples or a RR. The method extends our previous algorithm for estimating non-displaceable distribution volumes (VND) without using a RR...
November 14, 2016: NeuroImage
https://www.readbyqxmd.com/read/27806976/secular-trends-for-skinfolds-differ-from-those-for-bmi-and-waist-circumference-among-adults-examined-in-nhanes-from-1988-1994-through-2009-2010
#10
David S Freedman, Babette S Zemel, Cynthia L Ogden
BACKGROUND: Although the prevalence of a body mass index [BMI (in kg/m(2))] ≥30 has tripled among US adults since the 1960s, BMI is only moderately correlated with body fatness. Because skinfolds can more accurately estimate body fatness than can BMI, it is possible that skinfolds could be useful in monitoring secular trends in body fatness. OBJECTIVE: We examined whether there were similar secular trends for skinfolds (triceps and subscapular), BMI, and waist circumference between US adults...
November 2, 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27771334/exposure-and-preventive-behaviours-toward-ticks-and-lyme-disease-in-canada-results-from-a-first-national-survey
#11
Cécile Aenishaenslin, Catherine Bouchard, Jules K Koffi, Nicholas H Ogden
Lyme disease (LD) risk is increasing in Canada. In 2014, the government of Canada launched a national communication campaign to raise awareness and promote the adoption of individual preventive behaviours toward ticks and LD. The objectives of this study were to evaluate and compare the adoption of LD preventive behaviours and the exposure to tick bites of Canadians in the five main targeted regions (British Columbia, Prairie provinces, Ontario, Quebec and the Atlantic provinces). A national survey was conducted in December 2014 (n=2876) to collect data on LD awareness, behaviours and risk factors...
October 13, 2016: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/27758014/opsins-have-evolved-under-the-permanent-heterozygote-model-insights-from-phylotranscriptomics-of-odonata
#12
Anton Suvorov, Nicholas O Jensen, Camilla R Sharkey, M Stanley Fujimoto, Paul Bodily, Haley M Cahill Wightman, T Heath Ogden, Mark J Clement, Seth M Bybee
Gene duplication plays a central role in adaptation to novel environments by providing new genetic material for functional divergence and evolution of biological complexity. Several evolutionary models have been proposed for gene duplication to explain how new gene copies are preserved by natural selection but these models have rarely been tested using empirical data. Opsin proteins, when combined with a chromophore, form a photopigment that is responsible for the absorption of light, the first step in the phototransduction cascade...
October 18, 2016: Molecular Ecology
https://www.readbyqxmd.com/read/27742888/in%C3%A2-vivo-variation-in-same-day-estimates-of-metabotropic-glutamate-receptor-subtype-5-binding-using-11c-abp688-and-18f-fpeb
#13
Christine DeLorenzo, Jean-Dominique Gallezot, John Gardus, Jie Yang, Beata Planeta, Nabeel Nabulsi, R Todd Ogden, David C Labaree, Yiyun H Huang, J John Mann, Fabrizio Gasparini, Xin Lin, Jonathan A Javitch, Ramin V Parsey, Richard E Carson, Irina Esterlis
Positron emission tomography tracers [(11)C]ABP688 and [(18)F]FPEB target the metabotropic glutamate receptor subtype 5 providing quantification of the brain glutamatergic system in vivo. Previous [(11)C]ABP688 positron emission tomography human test-retest studies indicate that, when performed on the same day, significant binding increases are observed; however, little deviation is reported when scans are >7 days apart. Due to the small cohorts examined previously (eight and five males, respectively), we aimed to replicate the same-day test-retest studies in a larger cohort including both males and females...
October 14, 2016: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/27712012/impulsive-collision-dynamics-of-co-super-rotors-from-an-optical-centrifuge
#14
Matthew J Murray, Hannah M Ogden, Carlos Toro, Qingnan Liu, Amy S Mullin
We report state-resolved collision dynamics for CO molecules prepared in an optical centrifuge and measured with high-resolution transient IR absorption spectroscopy. Time-resolved polarization-sensitive measurements of excited CO molecules in the J=29 rotational state reveal that the oriented angular momentum of CO rotors is relaxed by impulsive collisions. The translational energy gains for molecules in the initial plane of rotation are threefold larger than for randomized angular momentum orientations, indicating the presence of anisotropic kinetic energy...
October 6, 2016: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/27708080/canada-aims-to-rewrite-environmental-law
#15
Lesley Evans Ogden
No abstract text is available yet for this article.
September 30, 2016: Science
https://www.readbyqxmd.com/read/27673313/use-of-projection-analyses-and-obesity-trends-reply
#16
LETTER
Katherine M Flegal, Cynthia L Ogden
No abstract text is available yet for this article.
September 27, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27668839/proteomic-and-genomic-characterization-of-a-yeast-model-for-ogden-syndrome
#17
Max J Dörfel, Han Fang, Jonathan Crain, Michael Klingener, Jake Weiser, Gholson J Lyon
Naa10 is a N(α) -terminal acetyltransferase that, in a complex with its auxiliary subunit Naa15, co-translationally acetylates the α-amino group of newly synthetized proteins as they emerge from the ribosome. Roughly 40-50% of the human proteome is acetylated by Naa10, rendering this an enzyme with one of the most broad substrate ranges known. Recently, we reported an X-linked disorder of infancy, Ogden syndrome, in two families harboring a c.109 T > C (p.Ser37Pro) variant in NAA10. In the present study we performed in-depth characterization of a yeast model of Ogden syndrome...
September 26, 2016: Yeast
https://www.readbyqxmd.com/read/27668560/the-central-role-of-physician-leadership-for-driving-change-in-value-based-care-environments
#18
Adam Lustig, Michael Ogden, Robert W Brenner, Jerry Penso, Kimberly D Westrich, Robert W Dubois
BACKGROUND: In 2013, it was reported that about 1 of every 3 U.S. adults has hypertension. Of these 70 million individuals, approximately 50% have their blood pressure under control. Achieving hypertension control, especially in at-risk populations, requires a multipronged approach that includes lifestyle modifications and pharmacological treatment. As provider groups, hospital systems, and integrated delivery networks optimize their care processes to promote population health activities in support of the accountable care organization (ACO) model of care, managing hypertension and other chronic diseases will be essential to their success...
October 2016: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/27667263/the-impact-of-an-implementation-intention-to-improve-mealtimes-and-reduce-jet-lag-in-long-haul-cabin-crew
#19
Cristina Ruscitto, Jane Ogden
OBJECTIVE: Jet lag is common place amongst long-haul cabin crew. Timed food has been shown to reset the circadian rhythm in rodents. Implementation intentions have been used to change eating behaviour. Mealtimes could therefore be used as a countermeasure to reduce jet lag and improve alertness in long-haul cabin crew through forming an implementation intention to improve the regularity of meals on days off. DESIGN: Sixty long-haul crew took part in a randomised controlled trial, with two conditions: forming an implementation intention to eat regular meals on days off vs...
October 14, 2016: Psychology & Health
https://www.readbyqxmd.com/read/27665265/evidence-of-rapid-changes-in-lyme-disease-awareness-in-canada
#20
Cécile Aenishaenslin, Catherine Bouchard, Jules K Koffi, Yann Pelcat, Nicholas H Ogden
Lyme disease (LD) is emerging in Canada. A key preventive strategy is promoting the adoption by the general public of personal preventive behaviors regarding tick bites. The aim of this study was to measure the changes in public awareness toward ticks and LD before and after the launch of a national communication campaign in Canada using data from two surveys conducted in March and December 2014. The results show a significant increase in awareness of LD after compared to before the campaign, but also suggest that the importance of this increase is not equal amongst Canadian regions...
October 2016: Ticks and Tick-borne Diseases
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