keyword
MENU ▼
Read by QxMD icon Read
search

Holzapfel

keyword
https://www.readbyqxmd.com/read/28421372/vascular-development-of-the-grapevine-vitis-vinifera-l-inflorescence-rachis-in-response-to-flower-number-plant-growth-regulators-and-defoliation
#1
Aude M Gourieroux, Bruno P Holzapfel, Margaret E McCully, Geoffrey R Scollary, Suzy Y Rogiers
The grapevine inflorescence is a determinate panicle and as buds emerge, shoot, flower and rachis development occur simultaneously. The growth and architecture of the rachis is determined by genetic and environmental factors but here we examined the role of flower and leaf number as well as hormones on its elongation and vascular development. The consequences of rachis morphology and vascular area on berry size and composition were also assessed. One week prior to anthesis, Merlot and Cabernet Sauvignon field vines were exposed to manual flower removal, exogenous plant growth regulators or pre-bloom leaf removal...
April 18, 2017: Journal of Plant Research
https://www.readbyqxmd.com/read/28415771/11c-choline-pet-ct-and-whole-body-mri-including-diffusion-weighted-imaging-for-patients-with-recurrent-prostate-cancer
#2
Hinrich Wieder, Ambros J Beer, Konstantin Holzapfel, Martin Henninger, Tobias Maurer, Sarah Schwarzenboeck, Ernst J Rummeny, Matthias Eiber, Jens Stollfuss
PURPOSE: To compare the detection efficacy of 11C-choline positron emission tomography and computed tomography (PET/CT) with whole-body magnetic resonance imaging (MRI) including diffusion-weighted imaging (DWI) in patients with suspected recurrent prostate cancer. MATERIAL AND METHODS: Fifty-seven patients (mean age 68, range 54-80 years) underwent 11C-choline PET/CT and MRI using T1-weighted (T1w), short-tau inversion recovery (STIR), and DWI. Two readers visually rated suspicious lesions on a 5-point scale in 20 different regions...
March 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28406991/a-mathematical-model-for-active-contraction-in-healthy-and-failing-myocytes-and-left-ventricles
#3
Li Cai, Yongheng Wang, Hao Gao, Yiqiang Li, Xiaoyu Luo
Cardiovascular disease is one of the leading causes of death worldwide, in particular myocardial dysfunction, which may lead to heart failure eventually. Understanding the electro-mechanics of the heart will help in developing more effective clinical treatments. In this paper, we present a multi-scale electro-mechanics model of the left ventricle (LV). The Holzapfel-Ogden constitutive law was used to describe the passive myocardial response in tissue level, a modified Grandi-Pasqualini-Bers model was adopted to model calcium dynamics in individual myocytes, and the active tension was described using the Niederer-Hunter-Smith myofilament model...
2017: PloS One
https://www.readbyqxmd.com/read/28402115/hole-transfer-processes-in-meta-and-para-conjugated-mixed-valence-compounds-unforeseen-effects-of-bridge-substituents-and-solvent-dynamics
#4
Julian Schäfer, Marco Holzapfel, Boryana Mladenova, Daniel Kattnig, Ivo Krummenacher, Holger Braunschweig, Günter Grampp, Christoph Lambert
To address the question whether donor substituents can be utilized to accelerate the hole transfer (HT) between redox sites attached in para- or in meta-positions to a central benzene bridge, we investigated three series of mixed valence compounds based on triarylamine redox centers that are connected to a benzene bridge via alkyne spacers at para- and meta-positions. The electron density at the bridge was tuned by substituents with different electron donating or accepting character. By analyzing optical spectra and by DFT computations we show that the HT properties are independent of bridge substituents for one of the meta-series, while donor substituents can strongly decrease the intrinsic barrier in the case of the para-series...
April 20, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28397957/single-cell-strain-energy-density-function-measured-by-cellular-micro-biaxial-stretching
#5
Zaw Win, Justin M Buksa, Kerianne E Steucke, G W Gant Luxton, Victor H Barocas, Patrick W Alford
The stress in a cell due to extracellular mechanical stimulus is determined by its mechanical properties, and the structural organization of many adherent cells suggests that their properties are anisotropic. This anisotropy may significantly influence the cells' mechanotransductive response to complex loads, and has important implications for development of accurate models of tissue biomechanics. Standard methods for measuring cellular mechanics report linear moduli that cannot capture large-deformation anisotropic properties, which in a continuum mechanics framework are best described by a strain energy density function (SED)...
April 11, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28374361/-cystic-renal-masses-as-an-incidental-finding-ultrasound-based-diagnostic-algorithm-and-therapeutic-consequences
#6
REVIEW
Konrad Friedrich Stock, Hubert Kübler, Konstantin Holzapfel
No abstract text is available yet for this article.
April 2017: MMW Fortschritte der Medizin
https://www.readbyqxmd.com/read/28346992/longitudinal-assessment-of-hydropeaking-impacts-on-various-scales-for-an-improved-process-understanding-and-the-design-of-mitigation-measures
#7
C Hauer, P Holzapfel, P Leitner, W Graf
Hydropeaking is one of the main pressures on the aquatic ecology in alpine rivers. Beside studies on abiotic process and biotic response on the local scale there is a lack in process understanding on the reach scale. Especially longitudinal changes of hydropeaking impacts based on retention processes have not been studied yet. Thus, based on unsteady one-dimensional and two-dimensional depth averaged modelling it was targeted to investigate possible changes in vertical ramping velocity for the discussion of possible mitigation measures at the local scale...
January 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28253234/engineering-a-humanized-bone-organ-model-in-mice-to-study-bone-metastases
#8
Laure C Martine, Boris M Holzapfel, Jacqui A McGovern, Ferdinand Wagner, Verena M Quent, Parisa Hesami, Felix M Wunner, Cedryck Vaquette, Elena M De-Juan-Pardo, Toby D Brown, Bianca Nowlan, Dan Jing Wu, Cosmo Orlando Hutmacher, Davide Moi, Tatiana Oussenko, Elia Piccinini, Peter W Zandstra, Roberta Mazzieri, Jean-Pierre Lévesque, Paul D Dalton, Anna V Taubenberger, Dietmar W Hutmacher
Current in vivo models for investigating human primary bone tumors and cancer metastasis to the bone rely on the injection of human cancer cells into the mouse skeleton. This approach does not mimic species-specific mechanisms occurring in human diseases and may preclude successful clinical translation. We have developed a protocol to engineer humanized bone within immunodeficient hosts, which can be adapted to study the interactions between human cancer cells and a humanized bone microenvironment in vivo. A researcher trained in the principles of tissue engineering will be able to execute the protocol and yield study results within 4-6 months...
April 2017: Nature Protocols
https://www.readbyqxmd.com/read/28220831/the-distribution-of-the-apparent-diffusion-coefficient-as-an-indicator-of-the-response-to-chemotherapeutics-in-ovarian-tumour-xenografts
#9
Monique C Tourell, Ali Shokoohmand, Marietta Landgraf, Nina P Holzapfel, Patrina S P Poh, Daniela Loessner, Konstantin I Momot
Diffusion-weighted magnetic resonance imaging (DW-MRI) was used to evaluate the effects of single-agent and combination treatment regimens in a spheroid-based animal model of ovarian cancer. Ovarian tumour xenografts grown in non-obese diabetic/severe-combined-immunodeficiency (NOD/SCID) mice were treated with carboplatin or paclitaxel, or combination carboplatin/paclitaxel chemotherapy regimens. After 4 weeks of treatment, tumours were extracted and underwent DW-MRI, mechanical testing, immunohistochemical and gene expression analyses...
February 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28187257/optical-fluorescence-detected-from-x-ray-irradiated-liquid-water
#10
Andreas Hans, Christian Ozga, Robert Seidel, Philipp Schmidt, Timo Ueltzhöffer, Xaver Holzapfel, Philip Wenzel, Philipp Reiß, Marvin N Pohl, Isaak Unger, Emad F Aziz, Arno Ehresmann, Petr Slavíček, Bernd Winter, André Knie
Despite its importance, the structure and dynamics of liquid water are still poorly understood in many apsects. Here, we report on the observation of optical fluorescence upon soft X-ray irradiation of liquid water. Detection of spectrally resolved fluorescence was achieved by a combination of the liquid microjet technique and fluorescence spectroscopy. We observe a genuine liquid-phase fluorescence manifested by a broad emission band in the 170-340 nm (4-7 eV) photon wavelength range. In addition, another narrower emission near 300 nm can be assigned to the fluorescence of OH (A state) in the gas phase, the emitting species being formed by Auger electrons escaping from liquid water...
March 1, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28168418/-acetabular-revision-arthroplasty-current-concepts-and-new-developments
#11
EDITORIAL
B M Holzapfel, M Rudert
No abstract text is available yet for this article.
February 2017: Der Orthopäde
https://www.readbyqxmd.com/read/28144717/-individualized-unicondylar-knee-replacement-use-of-patient-specific-implants-and-instruments
#12
J Arnholdt, B M Holzapfel, L Sefrin, M Rudert, J Beckmann, A F Steinert
OBJECTIVE: Unicompartmental knee replacement in patients with osteoarthritis (OA) of the medial compartment. Individualized instruments and implants with a planning protocol for optimal fit. The individualized instruments and implants (ConforMIS Inc.; Burlington, MA, USA) are manufactured based on a computed tomography scan of the affected lower extremity and are provided together with a planning protocol (iView®) of the surgery. INDICATIONS: Unicompartmental OA of the knee (Kellgren & Lawrence stage IV) or Morbus Ahlbäck after unsuccessful conservative or joint preserving surgery...
February 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28144716/bicompartmental-individualized-knee-replacement-use-of-patient-specific-implants-and-instruments-iduo%C3%A2
#13
A F Steinert, J Beckmann, B M Holzapfel, M Rudert, J Arnholdt
OBJECTIVE: Bicompartmental knee replacement in patients with combined osteoarthritis (OA) of the medial or lateral and patellofemoral compartment. Patient-specific instruments and implants (ConforMIS iDuo™) with a planning protocol for optimal implant fit. INDICATIONS: Bicompartmental OA of the knee (Kellgren & Lawrence stage IV) affecting both the medial or lateral and patellofemoral compartment after unsuccessful conservative or joint-preserving surgery. CONTRAINDICATIONS: Tricompartmental OA, knee ligament instabilities, knee deformities >15° (varus, valgus, extension deficit)...
February 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28115257/higher-order-structures-in-purine-and-pyrimidine-metabolism
#14
REVIEW
Iva Chitrakar, Deborah M Kim-Holzapfel, Weijie Zhou, Jarrod B French
The recent discovery of several forms of higher order protein structures in cells has shifted the paradigm of how we think about protein organization and metabolic regulation. These dynamic and controllable protein assemblies, which are composed of dozens or hundreds of copies of an enzyme or related enzymes, have emerged as important players in myriad cellular processes. We are only beginning to appreciate the breadth of function of these types of macromolecular assemblies. These higher order structures, which can be assembled in response to varied cellular stimuli including changing metabolite concentrations or signaling cascades, give the cell the capacity to modulate levels of biomolecules both temporally and spatially...
March 2017: Journal of Structural Biology
https://www.readbyqxmd.com/read/28092776/periosteum-tissue-engineering-in-an-orthotopic-in%C3%A2-vivo-platform
#15
J G Baldwin, F Wagner, L C Martine, B M Holzapfel, C Theodoropoulos, O Bas, F M Savi, C Werner, E M De-Juan-Pardo, D W Hutmacher
The periosteum plays a critical role in bone homeostasis and regeneration. It contains a vascular component that provides vital blood supply to the cortical bone and an osteogenic niche that acts as a source of bone-forming cells. Periosteal grafts have shown promise in the regeneration of critical size defects, however their limited availability restricts their widespread clinical application. Only a small number of tissue-engineered periosteum constructs (TEPCs) have been reported in the literature. A current challenge in the development of appropriate TEPCs is a lack of pre-clinical models in which they can reliably be evaluated...
March 2017: Biomaterials
https://www.readbyqxmd.com/read/28079117/high-field-transport-properties-of-a-p-doped-bafe2as2-film-on-technical-substrate
#16
Kazumasa Iida, Hikaru Sato, Chiara Tarantini, Jens Hänisch, Jan Jaroszynski, Hidenori Hiramatsu, Bernhard Holzapfel, Hideo Hosono
High temperature (high-Tc) superconductors like cuprates have superior critical current properties in magnetic fields over other superconductors. However, superconducting wires for high-field-magnet applications are still dominated by low-Tc Nb3Sn due probably to cost and processing issues. The recent discovery of a second class of high-Tc materials, Fe-based superconductors, may provide another option for high-field-magnet wires. In particular, AEFe2As2 (AE: Alkali earth elements, AE-122) is one of the best candidates for high-field-magnet applications because of its high upper critical field, Hc2, moderate Hc2 anisotropy, and intermediate Tc...
January 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28078371/acetabular-defect-classification-in-times-of-3d-imaging-and-patient-specific-treatment-protocols
#17
K Horas, J Arnholdt, A F Steinert, M Hoberg, M Rudert, B M Holzapfel
Parallel to the rising number of revision hip procedures, an increasing number of complex periprosthetic osseous defects can be expected. Stable long-term fixation of the revision implant remains the ultimate goal of the surgical protocol. Within this context, an elaborate preoperative planning process including anticipation of the periacetabular defect form and size and analysis of the remaining supporting osseous elements are essential. However, detection and evaluation of periacetabular bone defects using an unsystematic analysis of plain anteroposterior radiographs of the pelvis is in many cases difficult...
February 2017: Der Orthopäde
https://www.readbyqxmd.com/read/28012061/-treatment-of-acetabular-bone-defects-in-revision-hip-arthroplasty-using-the-revisio-system
#18
M Hoberg, B M Holzapfel, A F Steinert, F Kratzer, M Walcher, M Rudert
BACKGROUND: Many different systems for the management of primary and secondary acetabular defects are available, each with its inherent advantages and disadvantages. The Revisio-System is a press-fit oval mono-block implant that makes a defect-oriented reconstruction and restoration of the center of rotation possible. MATERIAL AND METHODS: In this study, we retrospectively reviewed the outcome of 92 consecutive patients treated with this oval press-fit cup due to periacetabular bone loss...
February 2017: Der Orthopäde
https://www.readbyqxmd.com/read/28009216/constraints-on-ultrahigh-energy-cosmic-ray-sources-from-a-search-for-neutrinos-above-10%C3%A2-pev-with-icecube
#19
M G Aartsen, K Abraham, M Ackermann, J Adams, J A Aguilar, M Ahlers, M Ahrens, D Altmann, K Andeen, T Anderson, I Ansseau, G Anton, M Archinger, C Argüelles, J Auffenberg, S Axani, X Bai, S W Barwick, V Baum, R Bay, J J Beatty, J Becker Tjus, K-H Becker, S BenZvi, P Berghaus, D Berley, E Bernardini, A Bernhard, D Z Besson, G Binder, D Bindig, M Bissok, E Blaufuss, S Blot, C Bohm, M Börner, F Bos, D Bose, S Böser, O Botner, J Braun, L Brayeur, H-P Bretz, A Burgman, T Carver, M Casier, E Cheung, D Chirkin, A Christov, K Clark, L Classen, S Coenders, G H Collin, J M Conrad, D F Cowen, R Cross, M Day, J P A M de André, C De Clercq, E Del Pino Rosendo, H Dembinski, S De Ridder, P Desiati, K D de Vries, G de Wasseige, M de With, T DeYoung, J C Díaz-Vélez, V di Lorenzo, H Dujmovic, J P Dumm, M Dunkman, B Eberhardt, T Ehrhardt, B Eichmann, P Eller, S Euler, P A Evenson, S Fahey, A R Fazely, J Feintzeig, J Felde, K Filimonov, C Finley, S Flis, C-C Fösig, A Franckowiak, E Friedman, T Fuchs, T K Gaisser, J Gallagher, L Gerhardt, K Ghorbani, W Giang, L Gladstone, M Glagla, T Glüsenkamp, A Goldschmidt, G Golup, J G Gonzalez, D Grant, Z Griffith, C Haack, A Haj Ismail, A Hallgren, F Halzen, E Hansen, B Hansmann, T Hansmann, K Hanson, D Hebecker, D Heereman, K Helbing, R Hellauer, S Hickford, J Hignight, G C Hill, K D Hoffman, R Hoffmann, K Holzapfel, K Hoshina, F Huang, M Huber, K Hultqvist, S In, A Ishihara, E Jacobi, G S Japaridze, M Jeong, K Jero, B J P Jones, M Jurkovic, A Kappes, T Karg, A Karle, U Katz, M Kauer, A Keivani, J L Kelley, J Kemp, A Kheirandish, M Kim, T Kintscher, J Kiryluk, T Kittler, S R Klein, G Kohnen, R Koirala, H Kolanoski, R Konietz, L Köpke, C Kopper, S Kopper, D J Koskinen, M Kowalski, K Krings, M Kroll, G Krückl, C Krüger, J Kunnen, S Kunwar, N Kurahashi, T Kuwabara, M Labare, J L Lanfranchi, M J Larson, F Lauber, D Lennarz, M Lesiak-Bzdak, M Leuermann, J Leuner, L Lu, J Lünemann, J Madsen, G Maggi, K B M Mahn, S Mancina, M Mandelartz, R Maruyama, K Mase, R Maunu, F McNally, K Meagher, M Medici, M Meier, A Meli, T Menne, G Merino, T Meures, S Miarecki, L Mohrmann, T Montaruli, M Moulai, R Nahnhauer, U Naumann, G Neer, H Niederhausen, S C Nowicki, D R Nygren, A Obertacke Pollmann, A Olivas, A O'Murchadha, T Palczewski, H Pandya, D V Pankova, Ö Penek, J A Pepper, C Pérez de Los Heros, D Pieloth, E Pinat, P B Price, G T Przybylski, M Quinnan, C Raab, L Rädel, M Rameez, K Rawlins, R Reimann, B Relethford, M Relich, E Resconi, W Rhode, M Richman, B Riedel, S Robertson, M Rongen, C Rott, T Ruhe, D Ryckbosch, D Rysewyk, L Sabbatini, S E Sanchez Herrera, A Sandrock, J Sandroos, S Sarkar, K Satalecka, M Schimp, P Schlunder, T Schmidt, S Schoenen, S Schöneberg, L Schumacher, D Seckel, S Seunarine, D Soldin, M Song, G M Spiczak, C Spiering, M Stahlberg, T Stanev, A Stasik, A Steuer, T Stezelberger, R G Stokstad, A Stößl, R Ström, N L Strotjohann, G W Sullivan, M Sutherland, H Taavola, I Taboada, J Tatar, F Tenholt, S Ter-Antonyan, A Terliuk, G Tešić, S Tilav, P A Toale, M N Tobin, S Toscano, D Tosi, M Tselengidou, A Turcati, E Unger, M Usner, J Vandenbroucke, N van Eijndhoven, S Vanheule, M van Rossem, J van Santen, J Veenkamp, M Vehring, M Voge, M Vraeghe, C Walck, A Wallace, M Wallraff, N Wandkowsky, Ch Weaver, M J Weiss, C Wendt, S Westerhoff, B J Whelan, S Wickmann, K Wiebe, C H Wiebusch, L Wille, D R Williams, L Wills, M Wolf, T R Wood, E Woolsey, K Woschnagg, D L Xu, X W Xu, Y Xu, J P Yanez, G Yodh, S Yoshida, M Zoll
We report constraints on the sources of ultrahigh-energy cosmic rays (UHECRs) above 10^{9}  GeV, based on an analysis of seven years of IceCube data. This analysis efficiently selects very high- energy neutrino-induced events which have deposited energies from 5×10^{5}  GeV to above 10^{11}  GeV. Two neutrino-induced events with an estimated deposited energy of (2.6±0.3)×10^{6}  GeV, the highest neutrino energy observed so far, and (7.7±2.0)×10^{5}  GeV were detected. The atmospheric background-only hypothesis of detecting these events is rejected at 3...
December 9, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27989920/mechanical-characterization-of-human-brain-tissue
#20
S Budday, G Sommer, C Birkl, C Langkammer, J Haybaeck, J Kohnert, M Bauer, F Paulsen, P Steinmann, E Kuhl, G A Holzapfel
Mechanics are increasingly recognized to play an important role in modulating brain form and function. Computational simulations are a powerful tool to predict the mechanical behavior of the human brain in health and disease. The success of these simulations depends critically on the underlying constitutive model and on the reliable identification of its material parameters. Thus, there is an urgent need to thoroughly characterize the mechanical behavior of brain tissue and to identify mathematical models that capture the tissue response under arbitrary loading conditions...
October 27, 2016: Acta Biomaterialia
keyword
keyword
105092
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"