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Neuroophthalmology

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https://www.readbyqxmd.com/read/27885957/visual-pathway-impairment-by-pituitary-adenomas-quantitative-diagnostics-by-diffusion-tensor-imaging
#1
Ylva Lilja, Oscar Gustafsson, Maria Ljungberg, Göran Starck, Bertil Lindblom, Thomas Skoglund, Henrik Bergquist, Karl-Erik Jakobsson, Daniel Nilsson
OBJECTIVE Despite ample experience in surgical treatment of pituitary adenomas, little is known about objective indices that may reveal risk of visual impairment caused by tumor growth that leads to compression of the anterior visual pathways. This study aimed to explore diffusion tensor imaging (DTI) as a means for objective assessment of injury to the anterior visual pathways caused by pituitary adenomas. METHODS Twenty-three patients with pituitary adenomas, scheduled for transsphenoidal tumor resection, and 20 healthy control subjects were included in the study...
November 25, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27872777/optic-disk-pit-with-sudden-central-visual-field-scotoma
#2
Nikol Panou, Demetrios G Vavvas
Purpose. To describe a case of optic disk pit (ODP) with sudden central visual field scotoma. Methods. A 49-year-old woman presented, reporting sudden painless central visual field loss 3 months prior to presentation. Neuroophthalmologic, systematic, and laboratory evaluation and full imaging processes were performed. Results. Fundoscopy and color photography demonstrated an optic disk pit inferotemporally. Perimetry identified central visual field horizontal scotoma. OCT revealed absence of serous retinal detachment, but disclosed inner retina thinning corresponding to the area of the visual field loss...
2016: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/27612674/visual-pathway-abnormalities-in-tuberculous-meningitis
#3
Pradeep Kumar Maurya, Ajai Kumar Singh, Lalit Sharma, Dinkar Kulshreshtha, Anup Kumar Thacker
Ophthalmological complications are common and disabling in patients with tuberculous meningitis. We aimed to study the visual pathway abnormalities in patients with tuberculous meningitis. Forty-three patients with tuberculous meningitis were subjected to visual evoked responses (VER) and neuroophthalmologic assessment. Neuroophthalmologic assessment revealed abnormalities in 22 (51.3%) patients. VER were found to be abnormal in 27 (62.8%) patients. The VER abnormalities included prolonged P100 latencies with relatively normal amplitude and significant interocular latency differences...
November 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27540757/the-sellar-and-suprasellar-region-a-hideaway-of-rare-lesions-clinical-aspects-imaging-findings-surgical-outcome-and-comparative-analysis
#4
Ioannis Petrakakis, Ariyan Pirayesh, Joachim K Krauss, Peter Raab, Christian Hartmann, Makoto Nakamura
OBJECTIVE: Apart from the "common" lesions (e.g. pituitary adenomas, Rathke's cleft cysts, meningiomas and craniopharyngiomas), there is a plethora of rare tumors or tumor-mimicking lesions in the sellar and suprasellar region (SSR). Due to a lack of characteristic imaging features, there is a dilemma in distinguishing these rare lesions from the more "common" ones preoperatively. Consequently, both diagnosis and definition of surgical goals, as well as further treatment strategies continue to be challenging for all attending physicians...
October 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27293943/topiramate-induced-persistent-eyelid-myokymia
#5
Mohammadrasoul Khalkhali
Background. Topiramate (TPM) is a psychotropic drug, which is used mainly as an antiepileptic drug and now over the years is used for a wider range of indications, including migraine prophylaxis and binge eating disorders. Although ocular side effects of Topiramate have been frequently reported, neuroophthalmologic manifestations such as myokymia are rarely reported. Case Presentation. This case report presents a case of a 47-year-old woman who had begun TPM for binge eating problem. She developed unilateral long standing lower eyelid twitching, which progressed to upper eyelid and eyebrow at the same side...
2016: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/27013899/peribulbar-anesthesia-causing-bilateral-orbital-hemorrhage
#6
Kyla Garft, Peter Burt, Benjamin Burt
We report a case of bilateral orbital hemorrhage as a complication of peribulbar anesthesia in a 78 year old man. Initially, unilateral orbital hemorrhage occurred but quickly spread to the contralateral side. Neuroophthalmological assessment revealed a proptosed tense globe with normal retinovascular findings. Visual acuity was adversely affected and this was conservatively managed with no lasting ophthalmic sequela. This patient's case was reported as it illustrates an unusual complication of bilateral spread of orbital hemorrhage secondary to peribulbar anesthesia...
2016: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/26971985/-optic-chiasm-glioma-in-children-endocrine-disorders-in-14-cases
#7
Emilio García García, Catalina Márquez Vega, Manuel Fajardo Cascos, Eva Venegas Moreno, Alfonso Soto Moreno
BACKGROUND AND OBJECTIVES: To describe the frequency of endocrine disorders in children with optic chiasm glioma and analyze related factors. PATIENTS AND METHODS: Review of medical records by collecting sex, age, history of neurofibromatosis, clinical presentation, treatment of tumour, and presence of endocrine abnormalities. Statistical tests Wilcoxon and Fisher. RESULTS: 14 patients (6 female) with age at diagnosis of 0.5 to 7.0 years (mean±standard deviation: 2...
May 20, 2016: Medicina Clínica
https://www.readbyqxmd.com/read/26339851/endonasal-endoscopic-transsphenoidal-chiasmapexy-using-a-clival-cranial-base-cranioplasty-for-visual-loss-from-massive-empty-sella-following-macroprolactinoma-treatment-with-bromocriptine-case-report
#8
G Rene Alvarez Berastegui, Shaan M Raza, Vijay K Anand, Theodore H Schwartz
Visual deterioration after dopamine-agonist treatment of prolactinomas associated with empty sella syndrome and secondary optic apparatus traction is a rare event. Chiasmapexy has been described as a viable treatment option, although few cases exist in the literature. Here, a novel endonasal endoscopic approach to chiasmapexy is described and its efficacy is demonstrated in a case report. A 55-year-old female patient with a history of a giant prolactinoma and 14 years of treatment using dopaminergic agonist therapy presented to our institution with a 1-month history of visual changes...
April 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/26162031/neuroophthalmological-outcomes-associated-with-use-of-the-pipeline-embolization-device-analysis-of-the-pufs-trial-results
#9
MULTICENTER STUDY
Daniel H Sahlein, Mohammad Fouladvand, Tibor Becske, Isil Saatci, Cameron G McDougall, István Szikora, Giuseppe Lanzino, Christopher J Moran, Henry H Woo, Demetrius K Lopes, Aaron L Berez, Daniel J Cher, Adnan H Siddiqui, Elad I Levy, Felipe C Albuquerque, David J Fiorella, Zsolt Berentei, Miklos Marosfoi, Saruhan H Cekirge, David F Kallmes, Peter K Nelson
OBJECT: Neuroophthalmological morbidity is commonly associated with large and giant cavernous and supraclinoid internal carotid artery (ICA) aneurysms. The authors sought to evaluate the neuroophthalmological outcomes after treatment of these aneurysms with the Pipeline Embolization Device (PED). METHODS: The Pipeline for Uncoilable or Failed Aneurysms (PUFS) trial was an international, multicenter prospective trial evaluating the safety and efficacy of the PED...
October 2015: Journal of Neurosurgery
https://www.readbyqxmd.com/read/25962425/-story-of-the-papilla-a-case-report
#10
A Beňová, P Kuthan, B Kousal, P Diblík, M Meliška
PURPOSE: To present a case report with "unclear" and sudden decrease of left eye visual acuity and bilateral visual fields defects. METHODS: A case report. CASE PRESENTATION: A 66-year-old woman was referred to our Center of Neuroophthalmology and Orbitology by a neurologist for a history of sudden decrease of visual acuity of her left eye 3 years ago. From September 2009, she was examined at various and not only ophthalmology departments...
April 2015: Ceská a Slovenská Oftalmologie
https://www.readbyqxmd.com/read/25960700/non-glaucomatous-optic-neuropathy-in-ibadan-extrapolations-to-healthcare-funding-in-nigeria
#11
O A Ogun, O A Adediran
BACKGROUND: Optic neuropathy is not a diagnosis in itself, as potential aetiologies are myriad. A pilot study conducted in the Eye Clinic, University College Hospital, Ibadan, between September 2007 and November 2009, showed that 46.8% of new cases presenting to the neuroophthalmology unit, had non-glaucomatous optic neuropathy (NGON) in which, the precise aetiology of optic neuropathy was never diagnosed. METHODS: All cases of NGON, seen in the neuro-ophthalmology unit, between September 2007 and June 2014 were analyzed to determine common aetiologies and identify the difficulties encountered in their investigation or management...
December 2014: Annals of Ibadan Postgraduate Medicine
https://www.readbyqxmd.com/read/25828425/eyelid-myokymia-in-patients-with-migraine-taking-topiramate
#12
V Medrano-Martínez, A Pérez-Sempere, J M Moltó-Jordá, S Fernández-Izquierdo, I Francés-Pont, J Mallada-Frechin, L Piqueras-Rodríguez
OBJECTIVE: Although ocular side effects of topiramate are common, neuroophthalmologic manifestations such as blepharospasm, myokymia and oculogyric crisis are scarcely reported. METHODS: We present a serie of 8 patients with migraine who developed eyelid myokymia after treatment with topiramate. We reviewed all patients with migraine treated with topiramate attending the headache outpatient clinic of our hospital from January 2008 to December 2012. RESULTS: During the study period, a total of 140 patients with migraine were treated with topiramate in our headache clinic...
August 2015: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/25419667/-neuroophthalmology-in-advanced-medical-training-at-german-university-eye-hospitals
#13
H Wilhelm, G C Y Haberl, F Beisse
No abstract text is available yet for this article.
November 2014: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/25419666/-editorial-neuroophthalmology-and-guidelines
#14
EDITORIAL
Helmut Wilhelm
No abstract text is available yet for this article.
November 2014: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/25313123/historical-vignette-henri-parinaud-1844-1905-french-ophthalmologist-and-pioneer-in-neuroophthalmology
#15
Gill Roper-Hall
No abstract text is available yet for this article.
2014: American Orthoptic Journal
https://www.readbyqxmd.com/read/25267340/compound-heterozygous-pnpla6-mutations-cause-boucher-neuh%C3%A3-user-syndrome-with-late-onset-ataxia
#16
A Deik, B Johannes, J C Rucker, E Sánchez, S E Brodie, E Deegan, K Landy, Y Kajiwara, S Scelsa, R Saunders-Pullman, C Paisán-Ruiz
PNPLA6 mutations, known to be associated with the development of motor neuron phenotypes, have recently been identified in families with Boucher-Neuhäuser syndrome. Boucher-Neuhäuser is a rare autosomal recessive syndrome characterized by the co-occurrence of cerebellar ataxia, hypogonadotropic hypogonadism, and chorioretinal dystrophy. Gait ataxia in Boucher-Neuhäuser usually manifests before early adulthood, although onset in the third or fourth decade has also been reported. However, given the recent identification of PNPLA6 mutations as the cause of this condition, the determining factors of age of symptom onset still need to be established...
December 2014: Journal of Neurology
https://www.readbyqxmd.com/read/24954414/relationship-between-contrast-sensitivity-test-and-disease-severity-in-multiple-sclerosis-patients
#17
A Soler García, A González Gómez, L C Figueroa-Ortiz, A García-Ben, J García-Campos
OBJECTIVE: To assess the importance of the Pelli-Robson contrast sensitivity test in multiple sclerosis patients according to the Expanded Disability Status Scale (EDSS). MATERIAL AND METHODS: A total of 62 patients with multiple sclerosis were included in a retrospective study. Patients were enrolled from the Neurology Department to Neuroophthalmology at Virgen de la Victoria Hospital. Patients were classified into 3 groups according to EDSS: group A) lower than 1...
September 2014: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/24715412/-paul-julius-m%C3%A3-bius-a-pacemaker-in-the-history-of-neuroophthalmology
#18
C Schobess, H Steinberg
No abstract text is available yet for this article.
May 2014: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/24701571/spinal-anesthesia-for-knee-arthroscopy-using-isobaric-bupivacaine-and-levobupivacaine-anesthetic-and-neuroophthalmological-assessment
#19
RANDOMIZED CONTROLLED TRIAL
Monica del-Rio-Vellosillo, Jose Javier Garcia-Medina, Antonio Abengochea-Cotaina, Maria Dolores Pinazo-Duran, Manuel Barbera-Alacreu
INTRODUCTION: The aim of the study was to compare the sensory, motor, and neuroophthalmological effects of isobaric levobupivacaine and bupivacaine when intrathecally administered. MATERIALS AND METHODS: A prospective, double-blind, randomized study with 60 ASA grade I-II patients aged 18-65 years awaiting knee arthroscopy under spinal anesthesia. Patients received 12.5 mg of isobaric bupivacaine or levobupivacaine. Several features were recorded. RESULTS: No significant intergroup differences were observed for ASA classification, time to micturate, demographic data, surgery duration, and patient/surgeon satisfaction...
2014: BioMed Research International
https://www.readbyqxmd.com/read/24600624/review-on-hypothetical-implementing-tgf-%C3%AE-family-members-in-glaucoma-therapy
#20
Ivan Sosa, Kata Culina, Alan Bosnar
For quite some time, glaucoma has been regarded as more than just intraocular pressure [IOP] elevation. Significant contribution to this conceptual improvement has risen from a better understanding of ocular blood flow, vessel wall integrity and certain advanced ideas in neuroophthalmology, for example neuroprotection. Transforming growth factor-β (TGF-β) molecule, its inhibitors and antagonists have been increasingly researched as possible new anti-glaucoma drugs for its many, pleiotropic, effects. Among those effects, enhancing fibrosis is one of the most apparent, but certain members of this cytokine's superfamily act as anti-fibrotics...
2012: Medical Hypothesis, Discovery and Innovation in Ophthalmology
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