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chads vasc

Sun-Wook Kim, Sol-Ji Yoon, Jung-Yeon Choi, Min-Gu Kang, Kwang-Il Kim, Cheol-Ho Kim
OBJECTIVE: Atrial fibrillation is the common arrhythmia in the elderly, and the average age of atrial fibrillation patients is rising. Elderly patients with atrial fibrillation have high incidence of thromboembolic complication and increasing age is associated with stroke severity. Assessing CHADS-VASc score is pivotal to evaluate substantial morbidity and mortality, especially regarding the increased risk of stroke. In addition, considering bleeding risk with HAS-BLED score is important to balance the benefit against the risk of bleeding...
September 2016: Journal of Hypertension
Victoria Chatzimavridou-Grigoriadou, Prodromos Kanavidis, Alexander G Mathioudakis
No abstract text is available yet for this article.
October 15, 2016: International Journal of Cardiology
Felipe Bisbal, Federico Gómez-Pulido, Pilar Cabanas-Grandío, Nazem Akoum, Mireia Calvo, David Andreu, Susanna Prat-González, Rosario J Perea, Roger Villuendas, Antonio Berruezo, Marta Sitges, Antoni Bayés-Genís, Josep Brugada, Nassir F Marrouche, Lluís Mont
BACKGROUND: Left atrial (LA) sphericity (LASP) is a new remodeling parameter based on LA shape analysis, with independent predictive value for recurrence after atrial fibrillation (AF) ablation. OBJECTIVES: To evaluate the association between LASP and thromboembolic events (TE) in patients with AF. METHODS: Twenty-nine AF patients and prior TE and 29 age- and gender-matched controls were included. LASP was calculated using a 3D-LA reconstruction...
July 2016: Journal of Cardiovascular Electrophysiology
Julien Ternacle, Nicolas Lellouche, Jean-François Deux, Jean-Luc Dubois-Randé, Emmanuel Teiger, Pascal Lim
AIMS: We evaluated the safety and feasibility of an intracardiac echocardiography probe through the oesophageal route (ICE-TEE) for the monitoring of left atrial appendage (LAA) closure to avoid general anaesthesia. METHODS AND RESULTS: The study included 16 consecutive patients (75±7 years) in atrial fibrillation with high embolism (CHADS-VASc=5±1.4) and bleeding risk (HAS-BLED=4±0.9) referred for LAA closure (Amplatzer Cardiac Plug [ACP]). Standard TEE was performed before device implantation for LAA analysis...
December 2015: EuroIntervention
Burak Turan, Hakan Demir, Ayhan Mutlu, Tolga Daşlı, Ayhan Erkol, İsmail Erden
OBJECTIVE: A combination of warfarin and aspirin is associated with increased bleeding compared with warfarin monotherapy. The aim of the study was to investigate the incidence and appropriateness of the combination of warfarin and aspirin in patients with atrial fibrillation (AF) or mechanical heart valve (MHV). METHODS: This cross-sectional study included consecutive patients with AF or MHV on chronic warfarin therapy (>3 months) without acute coronary syndrome or have not undergone a revascularization procedure in the preceding year...
March 2016: Anatolian Journal of Cardiology
Christopher X Wong, Sarah W Lee, Siang Wei Gan, Rajiv Mahajan, Geetanjali Rangnekar, Rajeev K Pathak, Darragh Twomey, Carlee Schultz, Anand N Ganesan, Anthony G Brooks, Kurt C Roberts-Thomson, Alex Brown, Dennis H Lau, Prashanthan Sanders
BACKGROUND: Atrial fibrillation (AF) is a leading cause of preventable stroke in Australia. Given that anticoagulation therapy can significantly reduce this stroke risk, we sought to characterise anticoagulation use in Indigenous and non-Indigenous Australians with AF. METHODS: Administrative, clinical and prescription data from patients with AF were linked. Anticoagulation use was characterised according to guideline-recommended risk scores and Indigenous status...
July 15, 2015: International Journal of Cardiology
Jacqueline Saw, Peter Fahmy, Peggy DeJong, Mathieu Lempereur, Ryan Spencer, Michael Tsang, Kenneth Gin, John Jue, John Mayo, Patrick McLaughlin, Savvas Nicolaou
AIMS: Left atrial appendage (LAA) device imaging after endovascular closure is important to assess for device thrombus, residual leak, positioning, surrounding structures, and pericardial effusion. Cardiac CT angiography (CCTA) is well suited to assess these non-invasively. METHODS AND RESULTS: We report our consecutive series of non-valvular atrial fibrillation patients who underwent CCTA post-LAA closure with Amplatzer Cardiac Plug (ACP), Amulet (second generation ACP), or WATCHMAN devices...
November 2015: European Heart Journal Cardiovascular Imaging
Filip M Szymański, Krzysztof J Filipiak, Anna E Płatek, Marcin Kotkowski, Grzegorz Opolski
BACKGROUND: Erectile dysfunction (ED) is highly prevalent in patients with diseases of cardiovascular system, including patients with atrial fibrillation (AF). Reasons for this high co-prevalence include endothelial dysfunction, inflammation, oxidative and emotional stress associated with AF. Association of AF-induced prothrombotic state and possible microthrombi in penile arteries with ED remains unclear. The present study aims to assess if probability of AF-associated risk of peripheral thromboembolism may be associated with ED in AF patients...
2015: Cardiology Journal
Fredrik Holmqvist, Sunghee Kim, Benjamin A Steinberg, James A Reiffel, Kenneth W Mahaffey, Bernard J Gersh, Gregg C Fonarow, Gerald V Naccarelli, Paul Chang, James V Freeman, Peter R Kowey, Laine Thomas, Eric D Peterson, Jonathan P Piccini
OBJECTIVE: Atrial fibrillation (AF) often progresses from paroxysmal or persistent to more sustained forms, but the rate and predictors of AF progression in clinical practice are not well described. METHODS: Using the Outcomes Registry for Better Informed Treatment of AF, we analysed the incidence and predictors of progression and tested the discrimination and calibration of the HATCH (hypertension, age, TIA/stroke, chronic obstructive pulmonary disease, heart failure) and CHA₂DS₂VASc scores for identifying AF progression...
June 2015: Heart: Official Journal of the British Cardiac Society
Young Dae Kim, Kyung Yul Lee, Hyo Suk Nam, Sang Won Han, Jong Yun Lee, Han-Jin Cho, Gyu Sik Kim, Seo Hyun Kim, Myoung-Jin Cha, Seong Hwan Ahn, Seung-Hun Oh, Kee Ook Lee, Yo Han Jung, Hye-Yeon Choi, Sang-Don Han, Hye Sun Lee, Chung Mo Nam, Eun Hye Kim, Ki Jeong Lee, Dongbeom Song, Hui-Nam Park, Ji Hoe Heo
PURPOSE: In this study, we investigated the stroke mechanism and the factors associated with ischemic stroke in patients with nonvalvular atrial fibrillation (NVAF) who were on optimal oral anticoagulation with warfarin. MATERIALS AND METHODS: This was a multicenter case-control study. The cases were consecutive patients with NVAF who developed cerebral infarction or transient ischemic attack (TIA) while on warfarin therapy with an international normalized ratio (INR) ≥2 between January 2007 and December 2011...
March 2015: Yonsei Medical Journal
Anna Zielonka, Michał Tkaczyszyn, Maciej Mende, Wojciech Nowak, Konrad Rekucki, Przemysław Soczomski, Michał Zieliński, Robert Pociupany, Arleta Wilkins, Waldemar Banasiak, Piotr Ponikowski, Ewa A Jankowska
INTRODUCTION: Atrial fibrillation (AF) frequently coexists with other cardiovascular diseases. OBJECTIVES: The aim of this study was to assess the prevalence of AF in outpatients with stable coronary artery disease (CAD) and to determine clinical and laboratory parameters associated with the higher prevalence of this arrhythmia. In addition, we compared the indications for antithrombotic treatment using the older CHADS₂ and the currently used CHA₂DS₂-VASc scores...
2015: Polskie Archiwum Medycyny Wewnętrznej
Yihong Sun, Dayi Hu
OBJECTIVE: To describe the baseline characteristics and antithrombotic treatment of patients with non-valvular atrial fibrillation in the Chinese subgroup of GRAFIELD. METHODS: GARFIELD is an observational registry study for patients with newly diagnosed non-valvular atrial fibrillation. A total of 805 adult ( ≥18 years old) patients (mean age: (66.6 ± 11.4) years old, 39.4% female (n = 317)) diagnosed with non-valvular atrial fibrillation within the previous 6 weeks were recruited between December 2009 and October 2011 at 29 hospitals from China...
October 2014: Zhonghua Xin Xue Guan Bing za Zhi
Dmitry M Yaranov, Athanasios Smyrlis, Natalia Usatii, Amber Butler, Joann R Petrini, Jose Mendez, Mark K Warshofsky
Obstructive sleep apnea (OSA) is an independent risk factor for ischemic stroke that is not included in the usual cardioembolic risk assessments for patients with atrial fibrillation (AF). The aim of this study was to investigate the impact of OSA on stroke rate in patients with AF. Patients with AF and new diagnoses of OSA were identified from retrospective chart review. Those with histories of stroke at the time of the sleep study were excluded. The primary outcome was the incidence of stroke, determined by a physician investigator blinded to the results of polysomnography...
February 15, 2015: American Journal of Cardiology
Ann Marie Navar-Boggan, Jennifer A Rymer, Jonathan P Piccini, Wassim Shatila, Lauren Ring, Judith A Stafford, Sana M Al-Khatib, Eric D Peterson
BACKGROUND: There is no universally accepted algorithm for identifying atrial fibrillation (AF) patients and stroke risk using electronic data for use in performance measures. METHODS: Patients with AF seen in clinic were identified based on International Classification of Diseases, Ninth Revision(ICD-9) codes. CHADS(2) and CHA(2)DS(s)-Vasc scores were derived from a broad, 10-year algorithm using IICD-9 codes dating back 10 years and a restrictive, 1-year algorithm that required a diagnosis within the past year...
January 2015: American Heart Journal
Jun Gu, Fengpeng Jia, Panpan Feng
OBJECTIVE: To assess the correlation of CHADS₂and CHA₂DS₂-VASc scores for left atrial thrombus in patients with nonvalvular atrial fibrillation and the differences in the results between the two scoring systems. METHODS: A total of 397 patients with nonvalvular atrial fibrillation were enrolled in this study. The CHADS₂and CHA2DS2-VASc scoring systems were used for evaluating the risk of left atrial thrombus and their differences in the scores and risk stratifications were compared...
November 2014: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
Su-Kiat Chua, Huey-Ming Lo, Chiung-Zuan Chiu, Kou-Gi Shyu
BACKGROUND: Acute coronary syndrome (ACS) patients have a wide spectrum of risks for subsequent cardiovascular events and death. However, there is no simple, convenience scoring system to identify risk of adverse outcomes. We investigated whether CHADS₂ and CHA₂DS₂-VASc scores were useful tools to assess the risk for adverse events among ACS patients. METHODS: This observational prospective study was conducted at 39 hospitals. Totally 3,183 patients with ACS were enrolled, and CHADS₂ and CHA₂DS₂-VASc scores were calculated...
2014: PloS One
Ole De Backer, Anastasia M Loupis, Nikolaj Ihlemann, Niels G Vejlstrup, Lars Søndergaard, Olaf W Franzen
INTRODUCTION: In atrial fibrillation (AF) patients with an increased stroke risk, oral anticoagulation (OAC) is the standard treatment for stroke prevention. However, this therapy carries a high risk of major bleeding. Percutaneous closure of the left atrial appendage (LAA) is suggested as an alternative option for stroke prevention in AF patients with contraindication(s) for OAC treatment. MATERIAL AND METHODS: A total of 42 patients underwent percutaneous LAA closure...
August 2014: Danish Medical Journal
Julien Ternacle, Nicolas Lellouche, Jean-François Deux, Jean-Luc Dubois-Randé, Emmanuel Teiger, Pascal Lim
Aims: We evaluated the safety and feasibility of an intracardiac echocardiography probe through the oesophageal route (ICE-TEE) for the monitoring of left atrial appendage (LAA) closure to avoid general anaesthesia. Methods and results: The study included 16 consecutive patients (75±7 years) in atrial fibrillation with high embolism (CHADS-VASc=5±1.4) and bleeding risk (HAS-BLED=4±0.9) referred for LAA closure (Amplatzer Cardiac Plug [ACP]). Standard TEE was performed before device implantation for LAA analysis...
July 19, 2014: EuroIntervention
Kui-Kai Lau, Pak-Hei Chan, Kai-Hang Yiu, Yap-Hang Chan, Shasha Liu, Koon-Ho Chan, Chun-Yip Yeung, Sheung-Wai Li, Hung-Fat Tse, Chung-Wah Siu
BACKGROUND: Patients with myocardial infarction (MI) are at risk of the development of atrial fibrillation (AF) and ischemic stroke. We sought to evaluate the prognostic performance of the CHADS₂ and CHA₂DS₂-VASc scores in predicting new AF and/or ischemic stroke in post-ST segment elevation MI (STEMI) patients. Six hundred and seven consecutive post-STEMI patients with no previously documented AF were studied. METHODS AND RESULTS: After a follow-up of 63 months (3,184 patient-years), 83 (13...
2014: Cardiology Journal
Taru Hallinen, Erkki J Soini, Christian Asseburg, Pekka Kuosmanen, Ari Laakkonen
OBJECTIVE: To assess the frequency of warfarin use, the achieved international normalised ratio (INR) balance among warfarin users and the primary healthcare outpatient costs of patients with atrial fibrillation (AF). DESIGN: Retrospective, non-interventional registry study. SETTING: Primary healthcare. PARTICIPANTS: All patients with AF (n=2746) treated in one Finnish health centre between October 2010 and March 2012...
2014: BMJ Open
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