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chads vasc

Cheng-Yang Hsieh, Cheng-Han Lee, Darren Philbert Wu, Sheng-Feng Sung
BACKGROUND AND AIMS: Early detection of atrial fibrillation after stroke is important for secondary prevention in stroke patients without known atrial fibrillation (AF). We aimed to compare the performance of CHADS2 , CHA2 DS2 -VASc and HATCH scores in predicting AF detected after stroke (AFDAS) and to test whether adding stroke severity to the risk scores improves predictive performance. METHODS: Adult patients with first ischemic stroke event but without a prior history of AF were retrieved from a nationwide population-based database...
May 2018: Atherosclerosis
Rixia Liu, Xiaomeng Yang, Shuya Li, Yong Jiang, Yilong Wang, Yongjun Wang
It is important to identify candidates who warrant extended cardiac monitoring after ischemic stroke. We investigated the predictive performance of the CHADS2 and CHA2 DS2 -VASc scores for previously unknown atrial fibrillation during in-hospital electrocardiographic monitoring. Patients were selected from a prospective trial in China. The clinical prediction of the scores was examined using the C statistic. Multivariate logistic regressions were performed to analyze the relevant risk factors. Among 1315 patients enrolled in study, previously unknown atrial fibrillation was detected in 110 (8...
May 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
Finlay A McAlister, Scott Garrison, Leanne Kosowan, Justin A Ezekowitz, Alexander Singer
BACKGROUND: As questions have been raised about the appropriateness of direct oral anticoagulant (DOAC) dosing among outpatients with atrial fibrillation, we examined this issue in patients being managed by primary care providers. METHODS AND RESULTS: This was a retrospective cohort new-user study using electronic medical records from 744 Canadian primary care clinicians. Potentially inappropriate DOAC prescribing was defined as prescribing lower or higher doses than those recommended by guidelines for patients with nonvalvular atrial fibrillation...
January 26, 2018: Journal of the American Heart Association
Henry J Henk, Feng Cao, Kenneth Tuell, Kwanza Price, Prianka Singh, Jack Mardekian, Kevin Odell, Chad Patel, Wilson Tan, George H Sands, Shalabh Singhal, Jeffrey Trocio, Lien Vo
OBJECTIVE: To evaluate inpatient oral anticoagulant (OAC) treatment, discharge location, and post-discharge OAC treatment for patients hospitalized with non-valvular atrial fibrillation (NVAF). RESEARCH DESIGN AND METHODS: Retrospective study using claims data linked to hospital electronic health records (EHR). Patients (n = 2,484) were hospitalized with a primary (38%) or secondary (62%) diagnosis of AF without evidence of mitral valvular heart disease or valve replacement between January 2009 and September 2013...
March 2018: Current Medical Research and Opinion
Julian P J Halcox, Kathie Wareham, Antonia Cardew, Mark Gilmore, James P Barry, Ceri Phillips, Michael B Gravenor
BACKGROUND: Asymptomatic atrial fibrillation (AF) is increasingly common in the aging population and implicated in many ischemic strokes. Earlier identification of AF with appropriate anticoagulation may decrease stroke morbidity and mortality. METHODS: We conducted a randomized controlled trial of AF screening using an AliveCor Kardia monitor attached to a WiFi-enabled iPod to obtain ECGs (iECGs) in ambulatory patients. Patients ≥65 years of age with a CHADS-VASc score ≥2 free from AF were randomized to the iECG arm or routine care (RC)...
November 7, 2017: Circulation
Jorge Romero, Juan Carlos Diaz, Luigi Di Biase, Saurabh Kumar, David Briceno, Usha B Tedrow, Carolina R Valencia, Samuel H Baldinger, Bruce Koplan, Laurence M Epstein, Roy John, Gregory F Michaud, William G Stevenson
BACKGROUND: Atrial fibrillation (AF) and cavotricuspid isthmus (CTI)-dependent atrial flutter (AFL) are two separate entities that coexist in a significant percentage of patients. We sought to investigate whether AF inducibility during CTI AFL ablation predicted the occurrence of AF at follow-up after successful AFL ablation. METHODS: A systemic review of Medline, Cochrane, and Embase was done for all the clinical studies in which assessment of AF inducibility in patients undergoing ablation for CTI AFL was performed...
April 2017: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
Bridget Frain, Ronald Castelino, Luke R Bereznicki
Oral anticoagulants are essential drugs for the prevention of thromboembolic events in patients with atrial fibrillation (AF). Anticoagulants are, however, commonly withheld in older people due to the risk and fear of hemorrhage. Although the underutilization of anticoagulants in patients with AF has been demonstrated internationally, few studies have been conducted among aged care residents. The aim of this study was to determine the utilization of anticoagulants among people with AF residing in aged care facilities...
April 2018: Clinical and Applied Thrombosis/hemostasis
Sun-Wook Kim, Sol-Ji Yoon, Jung-Yeon Choi, Min-Gu Kang, Kwang-Il Kim, Cheol-Ho Kim
OBJECTIVE: Atrial fibrillation is the common arrhythmia in the elderly, and the average age of atrial fibrillation patients is rising. Elderly patients with atrial fibrillation have high incidence of thromboembolic complication and increasing age is associated with stroke severity. Assessing CHADS-VASc score is pivotal to evaluate substantial morbidity and mortality, especially regarding the increased risk of stroke. In addition, considering bleeding risk with HAS-BLED score is important to balance the benefit against the risk of bleeding...
September 2016: Journal of Hypertension
Sun-Wook Kim, Sol-Ji Yoon, Jung-Yeon Choi, Min-Gu Kang, Kwang-Il Kim, Cheol-Ho Kim
OBJECTIVE: Atrial fibrillation is the common arrhythmia in the elderly, and the average age of atrial fibrillation patients is rising. Elderly patients with atrial fibrillation have high incidence of thromboembolic complication and increasing age is associated with stroke severity. Assessing CHADS-VASc score is pivotal to evaluate substantial morbidity and mortality, especially regarding the increased risk of stroke. In addition, considering bleeding risk with HAS-BLED score is important to balance the benefit against the risk of bleeding...
September 2016: Journal of Hypertension
Victoria Chatzimavridou-Grigoriadou, Prodromos Kanavidis, Alexander G Mathioudakis
No abstract text is available yet for this article.
October 15, 2016: International Journal of Cardiology
Felipe Bisbal, Federico Gómez-Pulido, Pilar Cabanas-Grandío, Nazem Akoum, Mireia Calvo, David Andreu, Susanna Prat-González, Rosario J Perea, Roger Villuendas, Antonio Berruezo, Marta Sitges, Antoni Bayés-Genís, Josep Brugada, Nassir F Marrouche, Lluís Mont
BACKGROUND: Left atrial (LA) sphericity (LASP) is a new remodeling parameter based on LA shape analysis, with independent predictive value for recurrence after atrial fibrillation (AF) ablation. OBJECTIVES: To evaluate the association between LASP and thromboembolic events (TE) in patients with AF. METHODS: Twenty-nine AF patients and prior TE and 29 age- and gender-matched controls were included. LASP was calculated using a 3D-LA reconstruction...
July 2016: Journal of Cardiovascular Electrophysiology
Julien Ternacle, Nicolas Lellouche, Jean-François Deux, Jean-Luc Dubois-Randé, Emmanuel Teiger, Pascal Lim
AIMS: We evaluated the safety and feasibility of an intracardiac echocardiography probe through the oesophageal route (ICE-TEE) for the monitoring of left atrial appendage (LAA) closure to avoid general anaesthesia. METHODS AND RESULTS: The study included 16 consecutive patients (75±7 years) in atrial fibrillation with high embolism (CHADS-VASc=5±1.4) and bleeding risk (HAS-BLED=4±0.9) referred for LAA closure (Amplatzer Cardiac Plug [ACP]). Standard TEE was performed before device implantation for LAA analysis...
December 2015: EuroIntervention
Burak Turan, Hakan Demir, Ayhan Mutlu, Tolga Daşlı, Ayhan Erkol, İsmail Erden
OBJECTIVE: A combination of warfarin and aspirin is associated with increased bleeding compared with warfarin monotherapy. The aim of the study was to investigate the incidence and appropriateness of the combination of warfarin and aspirin in patients with atrial fibrillation (AF) or mechanical heart valve (MHV). METHODS: This cross-sectional study included consecutive patients with AF or MHV on chronic warfarin therapy (>3 months) without acute coronary syndrome or have not undergone a revascularization procedure in the preceding year...
March 2016: Anatolian Journal of Cardiology
Christopher X Wong, Sarah W Lee, Siang Wei Gan, Rajiv Mahajan, Geetanjali Rangnekar, Rajeev K Pathak, Darragh Twomey, Carlee Schultz, Anand N Ganesan, Anthony G Brooks, Kurt C Roberts-Thomson, Alex Brown, Dennis H Lau, Prashanthan Sanders
BACKGROUND: Atrial fibrillation (AF) is a leading cause of preventable stroke in Australia. Given that anticoagulation therapy can significantly reduce this stroke risk, we sought to characterise anticoagulation use in Indigenous and non-Indigenous Australians with AF. METHODS: Administrative, clinical and prescription data from patients with AF were linked. Anticoagulation use was characterised according to guideline-recommended risk scores and Indigenous status...
July 15, 2015: International Journal of Cardiology
Jacqueline Saw, Peter Fahmy, Peggy DeJong, Mathieu Lempereur, Ryan Spencer, Michael Tsang, Kenneth Gin, John Jue, John Mayo, Patrick McLaughlin, Savvas Nicolaou
AIMS: Left atrial appendage (LAA) device imaging after endovascular closure is important to assess for device thrombus, residual leak, positioning, surrounding structures, and pericardial effusion. Cardiac CT angiography (CCTA) is well suited to assess these non-invasively. METHODS AND RESULTS: We report our consecutive series of non-valvular atrial fibrillation patients who underwent CCTA post-LAA closure with Amplatzer Cardiac Plug (ACP), Amulet (second generation ACP), or WATCHMAN devices...
November 2015: European Heart Journal Cardiovascular Imaging
Filip M Szymański, Krzysztof J Filipiak, Anna E Płatek, Marcin Kotkowski, Grzegorz Opolski
BACKGROUND: Erectile dysfunction (ED) is highly prevalent in patients with diseases of cardiovascular system, including patients with atrial fibrillation (AF). Reasons for this high co-prevalence include endothelial dysfunction, inflammation, oxidative and emotional stress associated with AF. Association of AF-induced prothrombotic state and possible microthrombi in penile arteries with ED remains unclear. The present study aims to assess if probability of AF-associated risk of peripheral thromboembolism may be associated with ED in AF patients...
2015: Cardiology Journal
Fredrik Holmqvist, Sunghee Kim, Benjamin A Steinberg, James A Reiffel, Kenneth W Mahaffey, Bernard J Gersh, Gregg C Fonarow, Gerald V Naccarelli, Paul Chang, James V Freeman, Peter R Kowey, Laine Thomas, Eric D Peterson, Jonathan P Piccini
OBJECTIVE: Atrial fibrillation (AF) often progresses from paroxysmal or persistent to more sustained forms, but the rate and predictors of AF progression in clinical practice are not well described. METHODS: Using the Outcomes Registry for Better Informed Treatment of AF, we analysed the incidence and predictors of progression and tested the discrimination and calibration of the HATCH (hypertension, age, TIA/stroke, chronic obstructive pulmonary disease, heart failure) and CHA₂DS₂VASc scores for identifying AF progression...
June 2015: Heart: Official Journal of the British Cardiac Society
Young Dae Kim, Kyung Yul Lee, Hyo Suk Nam, Sang Won Han, Jong Yun Lee, Han-Jin Cho, Gyu Sik Kim, Seo Hyun Kim, Myoung-Jin Cha, Seong Hwan Ahn, Seung-Hun Oh, Kee Ook Lee, Yo Han Jung, Hye-Yeon Choi, Sang-Don Han, Hye Sun Lee, Chung Mo Nam, Eun Hye Kim, Ki Jeong Lee, Dongbeom Song, Hui-Nam Park, Ji Hoe Heo
PURPOSE: In this study, we investigated the stroke mechanism and the factors associated with ischemic stroke in patients with nonvalvular atrial fibrillation (NVAF) who were on optimal oral anticoagulation with warfarin. MATERIALS AND METHODS: This was a multicenter case-control study. The cases were consecutive patients with NVAF who developed cerebral infarction or transient ischemic attack (TIA) while on warfarin therapy with an international normalized ratio (INR) ≥2 between January 2007 and December 2011...
March 2015: Yonsei Medical Journal
Anna Zielonka, Michał Tkaczyszyn, Maciej Mende, Wojciech Nowak, Konrad Rekucki, Przemysław Soczomski, Michał Zieliński, Robert Pociupany, Arleta Wilkins, Waldemar Banasiak, Piotr Ponikowski, Ewa A Jankowska
INTRODUCTION: Atrial fibrillation (AF) frequently coexists with other cardiovascular diseases. OBJECTIVES: The aim of this study was to assess the prevalence of AF in outpatients with stable coronary artery disease (CAD) and to determine clinical and laboratory parameters associated with the higher prevalence of this arrhythmia. In addition, we compared the indications for antithrombotic treatment using the older CHADS₂ and the currently used CHA₂DS₂-VASc scores...
2015: Polskie Archiwum Medycyny Wewnętrznej
Yihong Sun, Dayi Hu
OBJECTIVE: To describe the baseline characteristics and antithrombotic treatment of patients with non-valvular atrial fibrillation in the Chinese subgroup of GRAFIELD. METHODS: GARFIELD is an observational registry study for patients with newly diagnosed non-valvular atrial fibrillation. A total of 805 adult ( ≥18 years old) patients (mean age: (66.6 ± 11.4) years old, 39.4% female (n = 317)) diagnosed with non-valvular atrial fibrillation within the previous 6 weeks were recruited between December 2009 and October 2011 at 29 hospitals from China...
October 2014: Zhonghua Xin Xue Guan Bing za Zhi
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