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Dermatology guideline

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https://www.readbyqxmd.com/read/29774538/oral-propranolol-in-the-treatment-of-proliferating-infantile-haemangiomas-the-british-society-for-paediatric-dermatology-consensus-guidelines
#1
L Solman, M Glover, P E Beattie, H Buckley, S Clark, J E Gach, A Giardini, I Helbling, R J Hewitt, B Laguda, S M Langan, A E Martinez, R Murphy, L Proudfoot, J Ravenscroft, H Shahidullah, L Shaw, S B Syed, L Wells, C Flohr
BACKGROUND: Infantile haemangiomas (IH) are the most common vascular tumours of infancy. Despite their frequency and potential complications, there are currently no unified UK guidelines for the treatment of IH with propranolol. There are still uncertainties and diverse opinions regarding indications, pre-treatment investigations, its use in PHACES syndrome, and cessation of treatment. METHODS: This study used a modified Delphi technique, which involved an international treatment survey, a systematic evidence review of the literature, a face-to-face multidisciplinary panel meeting and anonymous voting...
May 17, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29763514/measurement-of-health-care-quality-in-atopic-dermatitis-development-and-application-of-a-set-of-quality-indicators
#2
S Steinke, F C Beikert, A Langenbruch, R Fölster-Holst, J Ring, J Schmitt, T Werfel, S Hintzen, N Franzke, M Augustin
BACKGROUND: Quality indicators are essential tools for the assessment of health care, in particular for guideline-based procedures. OBJECTIVE: 1) Development of a set of indicators for the evaluation of process and outcomes quality in atopic dermatitis (AD) care. 2) Application of the indicators to a cross-sectional study and creation of a global process quality index. METHODS: An expert committee consisting of 10 members of the German guideline group on atopic dermatitis condensed potential quality indicators to a final set of 5 outcomes quality and 12 process quality indicators using a Delphi panel...
May 15, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29729096/evaluation-of-the-appropriate-surgical-margin-for-pigmented-basal-cell-carcinoma-according-to-the-risk-factors-for-recurrence-a-single-institute-retrospective-study-in-japan
#3
Y Nakamura, K Tanese, I Hirai, K Kameyama, Y Kawakami, M Amagai, T Funakoshi
Basal cell carcinoma (BCC) is the most common skin cancer and tends to appear on the face and neck.1 For the complete removal of BCC, a surgical margin of at least 4mm is recommended by the guidelines of various dermatological and oncologic associations.2-4 However, 4mm is not always feasible because of anatomic and cosmetic restrictions. Moreover, these recommendations are based on studies of Caucasian non-pigmented BCCs. In contrast, most Asian BCCs are pigmented and relatively demarcated. This article is protected by copyright...
May 5, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29728839/development-of-minimum-standards-of-care-for-juvenile-localized-scleroderma
#4
REVIEW
Tamás Constantin, Ivan Foeldvari, Clare E Pain, Annamária Pálinkás, Peter Höger, Monika Moll, Dana Nemkova, Lisa Weibel, Melinda Laczkovszki, Philip Clements, Kathryn S Torok
Juvenile localized scleroderma (jLS), also known as morphea, is an orphan disease. Pediatric guidelines regarding diagnosis, assessment, and management are lacking.Our objective was to develop minimum standards of care for diagnosis, assessment, and management of jLS. A systematic review was undertaken to establish the pediatric evidence for assessment and monitoring of jLS. An expert panel, including members of the Pediatric Rheumatology European Society (PRES) Scleroderma Working Group, were invited to a consensus meeting where recommendations were developed based on evidence graded by the systematic review and, where evidence was lacking, consensus opinion...
May 4, 2018: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29722012/hydroxychloroquine-retinal-toxicity-in-two-patients-with-dermatological-conditions
#5
Tanya Kowalski, Christopher Baker, Heather G Mack
Two patients with dermatological conditions developed retinal toxicity after treatment with hydroxychloroquine that exceeded dosing recommendations. There is no treatment for hydroxychloroquine retinal toxicity and associated visual loss, so appropriate monitoring is imperative. All members of a patient's multidisciplinary team should be aware of the ocular risks of hydroxychloroquine, the importance of dosing within recommended guidelines and appropriate monitoring in reducing the risk of visual loss.
May 2, 2018: Australasian Journal of Dermatology
https://www.readbyqxmd.com/read/29714655/localized-morphea-after-breast-implant-for-breast-cancer-a-case-report
#6
A Moretti, F Bianchi, I V Abbate, G Gherardi, M Bonavita, E Passoni, G Nazzaro, A Bramati, M C Dazzani, S Piva, E Paternò, N Frungillo, G Farina, N La Verde
PURPOSE: Early breast cancer follow-up guidelines for patients who underwent surgery suggest a regular and accurate clinical examination of the breast area, for an early identification of cutaneous or subcutaneous breast cancer relapse. Nonetheless, breast skin lesions arising in patients treated with mastectomy for breast cancer can be caused by several diseases. A series of diagnostic hypotheses should be considered, not only focusing on cutaneous metastasis, but also on dermatologic and systemic diseases...
March 1, 2018: Tumori
https://www.readbyqxmd.com/read/29704768/management-of-treatment-related-toxicities-in-advanced-medullary-thyroid-cancer
#7
REVIEW
Marcia S Brose, Keith C Bible, Laura Q M Chow, Jill Gilbert, Carolyn Grande, Francis Worden, Robert Haddad
Progress in the treatment of advanced medullary thyroid cancer (MTC) has resulted from the approval of 2 drugs within the past 5 years, vandetanib and cabozantinib. These multikinase inhibitors (MKIs) possess overlapping specificities for multiple kinase targets implicated in the progression of MTC. Both drugs are associated with toxicities, including hypertension, hemorrhage/perforation, diarrhea and other gastrointestinal events, several dermatologic events, and hypothyroidism. In addition, vandetanib is uniquely associated with QTc prolongation through interaction with myocardial potassium channels, and cabozantinib is uniquely associated with hand-foot skin reaction...
April 22, 2018: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/29696437/sharp-decline-in-hydroxychloroquine-dosing-analysis-of-17-797-initiators-from-2007-to-2016
#8
Ronald B Melles, April M Jorge, Michael F Marmor, Yuqing Zhang, Hyon K Choi
We aimed to assess the impact of ophthalmology weight-based hydroxychloroquine (HCQ) dosing guidelines on prescribing patterns. We examined initial HCQ prescription dosing between 2007 and 2016 and determined independent predictors for HCQ dosing above the previous (2011) recommended ≤ 6.5 mg/kg of ideal body weight (IBW)/day and the latest (2016) recommended ≤ 5.0 mg/kg of actual body weight (ABW)/day using logistic regression. Among 17,797 patients (82% female), the proportion of 400 mg prescribed daily dosing declined sharply from 80% in 2007-2011 to nearly 40% in 2014, whereas the proportions of 200- and 300-mg daily doses showed the opposite trends during the same periods...
April 26, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29691869/hand-eczema-in-nurses-nursing-auxiliaries-and-cleaners-a-cross-sectional-study-from-a-tertiary-hospital-in-western-india
#9
Sanjeev B Gupta, Aayush Gupta, Bhavika Shah, Preeti Kothari, Sweety Darall, Dhara Boghara, Sukhnandan Sonkar, Kirti Deo
BACKGROUND: Healthcare workers have a high risk of developing hand eczema. OBJECTIVES: To determine the prevalence and severity of dermatologist-determined hand eczema among healthcare workers, carry out patch testing, and correlate the findings with impairment in quality of life (QoL) and demographic and vocational factors. METHODS: Seven hundred and ten healthcare workers (279 nurses, 246 cleaners, and 185 nursing auxiliaries) were screened for the presence of hand eczema...
April 25, 2018: Contact Dermatitis
https://www.readbyqxmd.com/read/29684517/nickel-related-adverse-reactions-in-the-treatment-of-cerebral-aneurysms-a-literature-review
#10
REVIEW
Anderson Chun On Tsang, Patrick Nicholson, Vitor Mendes Pereira
BACKGROUND: Nickel is the most common metal allergen and predominantly affects women. It is also the ubiquitous component in the alloys used to manufacture intracranial devices for aneurysm treatments, including aneurysm clips, self-expanding stents, flow-diverting stents and endosaccular occlusion devices. Adverse events related to nickel-allergy after deployment of such devices are uncommon but can be severe, resulting in dilemmas in the choice of treatment strategies and devices in managing nickel-sensitive patients with intracranial aneurysms...
April 20, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29676534/consensus-based-european-guidelines-for-treatment-of-atopic-eczema-atopic-dermatitis-in-adults-and-children-part-i
#11
A Wollenberg, S Barbarot, T Bieber, S Christen-Zaech, M Deleuran, A Fink-Wagner, U Gieler, G Girolomoni, S Lau, A Muraro, M Czarnecka-Operacz, T Schäfer, P Schmid-Grendelmeier, D Simon, Z Szalai, J C Szepietowski, A Taïeb, A Torrelo, T Werfel, J Ring
This guideline was developed as a joint interdisciplinary European project, including physicians from all relevant disciplines as well as patients. It is a consensus-based guideline, taking available evidence from other guidelines, systematic reviews and published studies into account. This first part of the guideline covers methods, patient perspective, general measures and avoidance strategies, basic emollient treatment and bathing, dietary intervention, topical anti-inflammatory therapy, phototherapy and antipruritic therapy, whereas the second part covers antimicrobial therapy, systemic treatment, allergen-specific immunotherapy, complementary medicine, psychosomatic counselling and educational interventions...
May 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29645380/s1-guidelines-dermatoses-associated-with-dermal-lymphostasis
#12
Joachim Dissemond, Finja Jockenhöfer, Anya Miller, Günter Kurzhals, Shahrouz Noori, Stefanie Reich-Schupke, Martin Schlaeger, Erich Schubert, Markus Stücker, Tobias Weberschock, Hans Wilfried Jungkunz
The objective of the present S1 guidelines is to present current knowledge about dermatologically relevant diseases associated with localized dermal lymphostasis, thus facilitating their early detection, diagnostic workup, and targeted treatment. Whenever possible, treatment should be based on stage-appropriate and clearly defined algorithms. The numerous issues regarding differential diagnosis and treatment clinicians are confronted with in everyday clinical practice seem to warrant the publication of up-to-date guidelines...
April 2018: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/29626322/a-scoping-review-protocol-to-explore-the-use-of-interleukin-1-targeting-drugs-for-the-treatment-of-dermatological-diseases-indications-mechanism-of-action-efficacy-and-safety
#13
REVIEW
Francisco Gómez-García, Juan Ruano, Jesús Gay-Mimbrera, Macarena Aguilar-Luque, Juan L Sanz-Cabanillas, José L Hernández Romero, Antonio Velez Garcia-Nieto
INTRODUCTION: The interleukin (IL)-1 pathway has been identified as being involved in inflammatory and neoplastic skin diseases such as psoriasis, atopic dermatitis, neutrophilic dermatosis, melanoma, and squamous cell carcinoma. Drugs developed to target the IL-1 pathway are currently used to treat these pathologies, and although they are becoming more selective, they are not exempt from adverse events and high costs. Integrating the best research evidence with clinical experience and patient needs has been shown to improve care, health, and cost outcomes...
April 6, 2018: Dermatology and Therapy
https://www.readbyqxmd.com/read/29614495/commentary-on-the-evidence-and-consensus-based-s3-guidelines-for-the-treatment-of-actinic-keratosis-published-by-the-international-league-of-dermatological-societies-in-cooperation-with-the-european-dermatology-forum
#14
Thomas L Diepgen, Joachim Kresken, Jean Krutmann, Hans F Merk, Erik Senger, Christian Surber, Rolf-Markus Szeimies
In 2015, the International League of Dermatological Societies and the European Dermatology Forum published a guideline for the treatment of actinic keratosis, which is classified as an evidence- and consensus-based S3 guideline. From the point of view of the GD Task Force "Licht.Hautkrebs.Prävention," an interdisciplinary expert panel of the Society for Dermopharmacy for the prevention and treatment of skin cancer, this guideline reveals strengths and weaknesses but, in summary, does not meet the claim for an evidence- and consensus-based S3 guideline...
April 3, 2018: Skin Pharmacology and Physiology
https://www.readbyqxmd.com/read/29600832/bullous-pemphigoid-italian-guidelines-adapted-from-edf-eadv-guidelines
#15
Emanuele Cozzani, Angelo V Marzano, Marzia Caproni, Claudio Feliciani, Piergiacomo Calzavara-Pinton
Bullous pemphigoid is the most common autoimmune subepidermal blistering disease of the skin and mucous membranes. This disease typically affects the elderly and presents with itch and localised or generalised bullous lesions. In up to 20% of affected patients blister may be completely absent, and only excoriations, prurigo-like lesions, eczematous lesions, urticated lesions, and/or infiltrated plaques are observed. The disease is significantly associated with neurological disorders. The morbidity of bullous pemphigoid and its impact on the quality of life are significant...
March 30, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29600693/photodynamic-therapy-for-esthetic-cosmetic-indications
#16
Wolfgang G Philipp-Dormston
Photodynamic therapy (PDT) is a well-established, non-invasive treatment for a variety of dermatologic disorders, including actinic keratosis. Furthermore, PDT results in marked improvements in the signs of skin aging, although currently there are no standardized guidelines for PDT in skin rejuvenation. Two types of PDT are available: conventional-PDT (c-PDT) and the newly introduced daylight-PDT (DL-PDT). Both require a topical photosensitizer, a light source and oxygen, and both are comparable regarding safety and efficacy for treatment of photo-induced skin aging...
March 29, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29582618/comparison-of-clinical-effects-trough-and-peak-levels-between-branded-and-generic-formulation-of-cyclosporine-in-stable-psoriatic-patients
#17
Cinzia Buligan, Caterina Pinzani, Rossella Cimarosti, Giuseppe Stinco, Massimo Baraldo
BACKGROUND: Cyclosporine A (CyA) is a drug for moderate-to-severe psoriasis. Recently, a generic formulation has been approved as bioequivalent to the branded one. The guidelines for the bioequivalence for critical-dose drugs with a narrow therapeutic range, such as CyA, are questionable. Therefore, it is important to assess the clinical outcome and the pharmacokinetics of different formulations in various patient groups. The current literature lacks of this information in dermatology...
March 26, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29577784/updated-standard-operating-procedures-for-electrochemotherapy-of-cutaneous-tumours-and-skin-metastases
#18
Julie Gehl, Gregor Sersa, Louise Wichmann Matthiessen, Tobian Muir, Declan Soden, Antonio Occhini, Pietro Quaglino, Pietro Curatolo, Luca G Campana, Christian Kunte, A James P Clover, Giulia Bertino, Victor Farricha, Joy Odili, Karin Dahlstrom, Marco Benazzo, Lluis M Mir
Electrochemotherapy is now in routine clinical use to treat cutaneous metastases of any histology, and is listed in national and international guidelines for cutaneous metastases and primary skin cancer. Electrochemotherapy is used by dermatologists, surgeons, and oncologists, and for different degrees and manifestations of metastases to skin and primary skin tumours not amenable to surgery. This treatment utilises electric pulses to permeabilize cell membranes in tumours, thus allowing a dramatic increase of the cytotoxicity of anti-cancer agents...
March 25, 2018: Acta Oncologica
https://www.readbyqxmd.com/read/29573103/efficacy-and-adverse-effects-of-topical-chloramphenicol-ointment-use-for-surgical-wounds-a-systematic-review
#19
REVIEW
Amanda Y Shen, Elie J Haddad, David J Hunter-Smith, Warren M Rozen
BACKGROUND: Chloramphenicol ointment is often used in plastic and dermatologic surgery as a topical antibiotic for surgical wounds, but evidence regarding its efficacy and side effects is lacking. In addition, anecdotal fear of aplastic anaemia exists from the oral use of this drug. We performed a systematic review of the literature to assess the efficacy and side effect profile of topical chloramphenicol ointment on non-ocular surgical wounds. METHODS: A systematic search of MEDLINE, EMBASE and the Cochrane Library from inception until 4 September 2017 was undertaken...
March 23, 2018: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29570708/dermatological-guidelines-for-monitoring-methotrexate-treatment-reduce-drug-survival-compared-to-rheumatological-guidelines
#20
Felien T M Busger Op Vollenbroek, Carine J M Doggen, René W A Janssens, Hein J Bernelot Moens
BACKGROUND: Methotrexate (MTX) is widely used as disease modifying treatment for psoriasis and psoriatic arthritis (PsA). Rheumatological and dermatological guidelines to prevent MTX-induced adverse events diverge in the number and frequency of blood tests. These differences are not based on evidence indicating a higher risk for patients with psoriasis compared to PsA or rheumatic arthritis (RA). This raises the question if multiple testing increases safety, or results in false positive signals potentially leading to early withdrawal of an effective treatment...
2018: PloS One
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