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Dermatology guideline

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https://www.readbyqxmd.com/read/28731005/preparing-medical-students-with-congenital-colour-vision-deficiency-for-safe-practice
#1
Rajat Dhingra, Jolly Rohatgi, Upreet Dhaliwal
BACKGROUND: Colour vision of candidates is tested in many medical colleges in India at the time of admission to undergraduate courses; however, there are no guidelines, and therefore no counselling, on how students with congenital colour vision deficiency (CCVD) should negotiate the medical course, and how best they can practise safely after graduation. Problems in interpreting coloured signs may lead to misdiagnosis. This study aimed to explore difficulties during clinical work that requires colour discrimination, and to offer suggestions on safe practice based on the findings and a review of the literature...
January 2017: National Medical Journal of India
https://www.readbyqxmd.com/read/28709817/evaluation-of-a-guidelines-based-approach-to-the-treatment-of-chronic-spontaneous-urticaria
#2
Jorge Sánchez, Josefina Zakzuk, Ricardo Cardona
BACKGROUND: International scientific associations have made recommendations for the management of chronic spontaneous urticaria (CSU) that have been summarized in clinical guidelines. OBJECTIVE: To evaluate the clinical impact of guideline recommendations for CSU management. METHODS: A multicenter, triple-blinded, prospective, randomized study (the Urticaria Research of Tropical Impact and Control Assessment project; ClinicalTrials.gov identifier: NCT01940393) was performed...
July 11, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28706297/harmless-effects-of-argon-plasma-on-caudal-fin-regeneration-and-embryogenesis-of-zebrafish-novel-biological-approaches-for-safe-medical-applications-of-bioplasma
#3
Min-Kyung Nam, Goo-Young Kim, Si-Eun Yun, Ja-Young Jang, Yong-Hee Kim, Eun Ha Choi, Seongman Kang, Hyangshuk Rhim
The argon plasma jet (Ar-PJ) is widely used in medical fields such as dermatology and dentistry, and it is considered a promising tool for cancer therapy. However, the in vivo effects of Ar-PJ for medical uses have not yet been investigated, and there are no biological tools to determine the appropriate clinical dosages of Ar-PJ. In this study, we used the caudal fin and embryo of zebrafish as novel in vivo tools to evaluate the biosafety of Ar-PJ. Typically, Ar-PJ is known to induce cell death in two-dimensional (2D) cell culture systems...
July 14, 2017: Experimental & Molecular Medicine
https://www.readbyqxmd.com/read/28681136/-german-national-consensus-on-wound-documentation-of-leg-ulcer-part%C3%A2-2-routine-care-classification-of-variable-characteristics
#4
REVIEW
K Herberger, K Heyer, K Protz, A Mayer, J Dissemond, S Debus, T Wild, J Schmitt, M Augustin
BACKGROUND: Standards in the assessment and documentation of disease processes are the basis of guideline-based care. For the treatment of chronic wounds, especially leg ulcers, no approved parameters are available. OBJECTIVES: Against this background, our aim was to develop standards for the documentation of leg ulcer in routine care. This article presents the recommendations for the classification and characteristics of the variables. MATERIALS AND METHODS: The development of the documentation standard was based on a systematic literature research and was performed in a Delphi-based consensus process...
July 5, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28678985/clinical-and-incidental-perineural-invasion-of-cutaneous-squamous-cell-carcinoma-a-systematic-review-and-pooled-analysis-of-outcomes-data
#5
Pritesh S Karia, Frederick C Morgan, Emily Stamell Ruiz, Chrysalyne D Schmults
Importance: Perineural invasion (PNI) in cutaneous squamous cell carcinoma (CSCC) has been associated with an increased risk of poor outcomes. Patients with PNI may present with clinical symptoms and/or radiologic evidence of PNI (clinical PNI [CPNI]), yet most patients are asymptomatic and PNI is often found on histologic examination (incidental PNI [IPNI]). Evidence-based estimates of the risks of disease-related outcomes comparing IPNI and CPNI are limited in the dermatology literature...
July 5, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28656728/minimum-standards-on-prevention-diagnosis-and-treatment-of-occupational-and-work-related-skin-diseases-in-europe-position-paper-of-the-cost-action-standerm-td-1206
#6
J H Alfonso, A Bauer, L Bensefa-Colas, A Boman, M Bubas, L Constandt, M N Crepy, M Goncalo, J Macan, V Mahler, D Mijakoski, J M Ramada Rodilla, T Rustemeyer, P Spring, S M John, W Uter, M Wilkinson, A M Giménez-Arnau
BACKGROUND: Skin diseases constitute up to 40% of all notified occupational diseases in most European countries, predominantly comprising contact dermatitis, contact urticaria, and skin cancer. While insufficient prevention of work-related skin diseases (WRSD) is a top-priority problem in Europe, common standards for prevention of these conditions are lacking. OBJECTIVE: To develop common European standards on prevention and management of WRSD and occupational skin diseases (OSD)...
June 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28646580/biosimilars-for-psoriasis-worldwide-overview-of-regulatory-guidelines-uptake-and-implications-for-dermatology-clinical-practice
#7
REVIEW
A D Cohen, J J Wu, L Puig, S Chimenti, R Vender, M Rajagopalan, R Romiti, C de la Cruz, L Skov, C Zachariae, H S Young, P Foley, J M van der Walt, L Naldi, A Blauvelt
The introduction of biologic drugs for the treatment of patients with psoriasis has revolutionized treatment paradigms and enabled numerous patients to achieve disease control with an acceptable safety profile. However, the high cost of biologics limits access to these medications for the majority of patients worldwide. In recent years, the introduction of biosimilars for inflammatory diseases has become a fast evolving field. The future use of biosimilars offers the potential for decreased cost and increased access to biologic drugs for patients with psoriasis...
June 24, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28628680/current-perspectives-among-u-s-dermatologists-on-chemoprevention-of-nonmelanoma-skin-cancer-a-survey-based-study
#8
Brittany Oliver, Serena Durrani, Joel L Cohen, Adam J Friedman
<p>Introduction: Nonmelanoma skin cancer (NMSC) is the most common malignancy in the US Primary prevention of NMSC with physical photoprotective measures are often not sufficient to impact skin cancer incidence in high-risk individuals. Chemoprevention is the use of agents to prevent, suppress, and reverse carcinogenic progression. Many agents have been investigated, but preclinical and clinical studies are often inconsistent.</p> <p>Methods: A cross-sectional study was designed to assess current practices, perceptions, and general knowledge of U...
May 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28628677/impact-of-a-31-gene-expression-profiling-test-for-cutaneous-melanoma-on-dermatologists-clinical-management-decisions
#9
Aaron S Farberg, Alex M Glazer, Richard White, Darrell S Rigel
<p>Importance: Current guidelines for cutaneous malignant melanoma (CMM) provide general recommendations regarding surveillance while indicating that management should be tailored to patients' individual probability of recurrence. A 31-gene expression profile (31-GEP) test to predict metastatic risk has been previously validated, and classifies patients as either Class 1 (low risk) or Class 2 (high risk).</p> <p>Objective: To determine the impact of the 31-GEP test's result on clinical decision-making...
May 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28598544/dermatological-manifestations-of-tuberous-sclerosis-complex-tsc
#10
REVIEW
Daniel Ebrahimi-Fakhari, Sascha Meyer, Thomas Vogt, Claudia Pföhler, Cornelia Sigrid Lissi Müller
Tuberous sclerosis complex (TSC) is a genetic multisystem disorder with prominent skin involvement that frequently occurs in early childhood. Dermatologic manifestations include facial angiofibromas, hypomelanotic macules, fibrous cephalic plaques, shagreen patches, and ungual fibromas. The International TSC Consensus Conference in 2012 provided guidelines for standardized baseline evaluation and follow-up. Detailed clinical dermatological evaluation at the time of diagnosis and annual skin examination is recommended for both pediatric and adult populations...
June 9, 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/28594706/diagnosis-of-tuberous-sclerosis-complex-in-a-patient-referred-for-uncontrolled-hypertension-and-renal-dysfunction-a-case-highlighting-the-importance-of-proper-diagnostic-work-up-of-hypertensive-patients
#11
Pantelis A Sarafidis, Athanasios Bikos, Charalampos Loutradis, Stergios Tzikas, Efstratios Vakirlis, Eugenia Avdelidou, Dimitrios Zafeiriou, Aikaterini Papagianni, Vasileios Vassilikos
: We report a case of a 39-year-old woman with resistant hypertension and renal dysfunction. The patient was hospitalized 3 months earlier for dyspnea at the Department of Cardiology, where she was diagnosed with heart failure (left ventricle injection fraction: 25-30%), pulmonary hypertension, chronic kidney disease (serum creatinine: 1.58 mg/dl), and resistant hypertension and discharged with optimal heart failure treatment. At presentation to our clinic, apart from uncontrolled hypertension for more than 10 years and history of pre-eclampsia and fetal loss, the patient had obesity (BMI: 38 kg/m) and facial fibromas...
June 7, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28593793/erratum
#12
(no author information available yet)
Yuka A, Tan J, Baibergenova A, Barankin B, Cochrane CL, Humphrey S, Lynde CW, Marcoux D, Poulin Y, Rivers JK, Sapijaszko M, Sibbald RG, Toole J, Ulmer M, Zip C. Canadian Clinical Practice Guidelines for Rosacea. J Cutan Med Surg. 2016;20(5):432-445. Original DOI: 10.1177/1203475416650427 In the above article, the author affiliation for Ulmer M should have been listed as Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC, Canada and Carruthers & Humphrey, Vancouver, BC, Canada...
June 1, 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28593645/ultraviolet-a-photosensitivity-profile-of-dexchlorpheniramine-maleate-and-promethazine-based-creams-anti-inflammatory-antihistaminic-and-skin-barrier-protection-properties
#13
Gustavo Facchini, Samara Eberlin, Stefano Piatto Clerici, Ana Lucia Tabarini Alves Pinheiro, Adilson Costa
BACKGROUND: Unwanted side effects such as dryness, hypersensitivity, and cutaneous photosensitivity are challenge for adherence and therapeutical success for patients using treatments for inflammatory and allergic skin response. AIMS: In this study, we compared the effects of two dermatological formulations, which are used in inflammatory and/or allergic skin conditions: dexchlorpheniramine maleate (DCP; 10 mg/g) and promethazine (PTZ; 20 mg/g). METHODS: We evaluated both formulations for phototoxicity potential, skin irritation, anti-inflammatory and antihistaminic abilities, and skin barrier repair in vitro and ex vivo using the standard OECD test guideline n° 432, the ECVAM protocol n° 78, and cultured skin explants from a healthy patient...
June 7, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28585191/why-topical-retinoids-are-mainstay-of-therapy-for-acne
#14
REVIEW
James Leyden, Linda Stein-Gold, Jonathan Weiss
Acne-focused dermatology expert groups have consistently recommended that most patients with acne be treated with a combination of topical retinoid and antimicrobial therapy. This is based on clinical data as well as evidence that these drug classes have different and complementary mechanisms of action that target multiple aspects of acne's complex pathophysiology. Recent evidence-based guidelines for acne, including those from the American Academy of Dermatology (AAD) and the European Dermatology Forum (EDF), have agreed that retinoids have an essential role in this widespread disease...
June 5, 2017: Dermatology and Therapy
https://www.readbyqxmd.com/read/28573316/-sarcoidosis-dermatological-view-of-a-rare-multisystem-disease
#15
REVIEW
T Giner, S Benoit, H Kneitz, M Goebeler
Sarcoidosis is a rare multisystem inflammatory disease of largely unknown etiology. While pulmonary sarcoidosis is the most abundant organ manifestation, involvement of the skin that occurs in up to 30% of patients is the most common extrapulmonary presentation of the disease. Dermatologists therefore play an important role not only for establishing the diagnosis and delineating it from potential differential diagnoses but also for the interdisciplinary care of the patient. The clinical presentation of skin sarcoidosis is manifold, which occasionally aggravates making the final diagnosis...
July 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28561292/guideline-for-the-diagnosis-and-treatment-of-scabies-in-japan-third-edition-executive-committee-of-guideline-for-the-diagnosis-and-treatment-of-scabies
#16
(no author information available yet)
In the current work, we present our new guideline for the diagnosis and treatment of scabies which we, the Executive Committee convened by the Japanese Dermatological Association, developed to ensure proper diagnosis and treatment of scabies in Japan. Approval of phenothrin topical use under the National Health Insurance in August 2014 led to this action. Permethrin, a topical anti-scabietic medication belonging to the same pyrethroid group as phenothrin, is already in use worldwide. In this guideline, we introduce criteria for a proper diagnosis of scabies, treatment algorithm for common and crusted (hyperkeratotic) scabies, and prevention...
May 31, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28556451/skin-cancers-in-organ-transplant-recipients
#17
Amit Mittal, Oscar R Colegio
Long-term utilization of immunosuppression in organ transplant recipients (OTRs) leads to decreased immune-mediated tumor surveillance and development of malignant tumors. A delicate balance needs to be maintained in the intensity of immunosuppression to keep the risk of malignancy low without jeopardizing life-saving graft function. OTRs are prone to developing skin cancers which exhibit unique epidemiologic, pathophysiologic and prognostic characteristics. In this review, we discuss the most commonly reported skin cancers in OTRs: squamous cell carcinoma (SCC), basal cell carcinoma (BCC), Kaposi's sarcoma, Merkel cell carcinoma and malignant melanoma (MM)...
May 29, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28532815/attitudes-and-practices-of-irish-hospital-based-physicians-towards-hand-hygiene-and-hand-rubbing-using-alcohol-based-hand-rub-a-comparison-between-2007-and-2015
#18
L M Kingston, B L Slevin, N H O'Connell, C P Dunne
BACKGROUND: Hand hygiene is the cornerstone of infection prevention and control practices, and reduces healthcare-associated infections significantly. However, international evidence suggests that medical doctors demonstrate poor compliance. AIM: To explore and compare practices and attitudes towards hand hygiene, particularly hand rubbing using alcohol-based hand rub (ABHR), among hospital-based physicians in Ireland between 2007 and 2015. METHODS: In 2007, a random sample of doctors in a large teaching hospital was invited to complete a postal survey using a validated questionnaire...
May 19, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28530054/-traditional-chinese-medicine-in-treatment-of-atopic-dermatitis
#19
Orit Schachter, David Perla, Shoshana Greenberger, Aviv Barzilai, Sharon Baum
BACKGROUND: Atopic dermatitis is a common chronic inflammatory skin disease, affecting up to 15-30% of children in industrialized countries. As there is no definitive cure for atopic dermatitis, patients often seek other complementary therapeutic options, such as traditional Chinese medicine (TCM). TCM comprises numerous treatment modalities for the management of atopic dermatitis including acupuncture and herbal medicine. We report a case of a two and a half year old child with atopic dermatitis exacerbation treated successfully with TCM...
October 2016: Harefuah
https://www.readbyqxmd.com/read/28516495/introduction-to-the-world-association-for-veterinary-dermatology-and-the-clinical-consensus-guidelines
#20
EDITORIAL
Aiden Foster, Wayne Rosenkrantz, Catherine Outerbridge, Tony Barnett
No abstract text is available yet for this article.
June 2017: Veterinary Dermatology
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