keyword
MENU ▼
Read by QxMD icon Read
search

Carotid artery disease

keyword
https://www.readbyqxmd.com/read/29665308/calcified-cerebral-emboli-incidence-and-implications
#1
Miguel Bardon, Julian Hanson, Bill O'Brien, Adil Naeem
INTRODUCTION: Calcified cerebral emboli are an increasingly recognized cause of ischaemic stroke, although recognition amongst general radiologists and clinicians can be limited. Recent literature suggests that calcified cerebral emboli are likely more common than originally thought. This study aims to define the prevalence of calcified cerebral emboli as the most likely aetiology within a cohort of confirmed cases of acute stroke, as well as compare and contrast these cases with cases of 'incidental' intracranial calcification...
April 17, 2018: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29664810/childhood-pulse-pressure-predicts-subclinical-vascular-damage-in-adulthood-the-beijing-blood-pressure-cohort-study
#2
Dongqing Hou, Yinkun Yan, Junting Liu, Xiaoyuan Zhao, Hong Cheng, Jie Mi
OBJECTIVE: We aimed to investigate associations of childhood pulse pressure (PP) and change in PP status with adult subclinical vascular damage. METHODS: Data were obtained from a population-based cohort of children aged 6-18 years started in 1987. The study constituted 1254 participants who were followed up in 2010-2011 (aged 28-42 years). Carotid arteriosclerosis and aortic stiffness were assessed by carotid intima-media thickness (IMT) and brachial-ankle pulse wave velocity (PWV), respectively...
April 16, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29663586/adiposity-body-composition-and-ventricular-arterial-stiffness-in-the-elderly-the-atherosclerosis-risk-in-communities-study
#3
Miguel M Fernandes-Silva, Amil M Shah, Brian Claggett, Susan Cheng, Hirofumi Tanaka, Odilson M Silvestre, Wilson Nadruz, Barry A Borlaug, Scott D Solomon
AIM: Weight gain appears to accelerate age-related ventricular-arterial stiffening, which has been implicated in the development of heart failure (HF), but it is unclear whether body fat accumulation underpins this association. We evaluated the relationship of adiposity, using measures of body composition, with ventricular-arterial stiffness among the elderly in the community. METHODS AND RESULTS: Adiposity was accessed through body mass index (BMI), waist circumference, and body fat percentage...
April 16, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29663514/combined-carotid-endarterectomy-and-transcatheter-aortic-valve-replacement-technique-and-outcomes
#4
Robert J Moraca, Anil A Shah, Stephen H Bailey, Daniel Benckart, David Lasorda, Ramzi Khalil, Bart Chess, Walter McGregor, Michael S Halbreiner
BACKGROUND: Stroke and transient ischemic attack after transcatheter aortic valve replacement results in significantly higher morbidity and mortality. Severe carotid artery disease may be a contributing factor to this increased risk. We report our technique and outcomes of combined carotid endarterectomy (CEA) with transcatheter aortic valve replacement (TAVR). METHODS: From March 2013 to November 2017 a total of 753 TAVRs were performed at our institution for symptomatic severe aortic stenosis...
April 16, 2018: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/29658889/cross-correlation-analysis-of-pulse-wave-propagation-in-arteries-i-in-vitro-i-validation-and-i-in-vivo-i-feasibility
#5
Pierre Nauleau, Iason Zacharias Apostolakis, Matthew McGarry, Elisa E Konofagou
The stiffness of the arteries is known to be an indicator of the progression of various cardiovascular diseases. Clinically, the pulse wave velocity (PWV) is used as a surrogate for the arterial stiffness. Pulse Wave Imaging (PWI) is a non-invasive, ultrasound-based imaging technique capable of mapping the motion of the vessel walls allowing local assessment of the arterial properties. Conventionally, a distinctive feature of the displacement wave (e.g. the 50% upstroke) is tracked across the map to estimate the PWV...
April 16, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29657758/temporal-and-spatial-changes-in-wall-shear-stress-during-atherosclerotic-plaque-progression-in-mice
#6
R Xing, A M Moerman, Y Ridwan, M J Daemen, A F W van der Steen, F J H Gijsen, K van der Heiden
Wall shear stress (WSS) is involved in atherosclerotic plaque initiation, yet its role in plaque progression remains unclear. We aimed to study (i) the temporal and spatial changes in WSS over a growing plaque and (ii) the correlation between WSS and plaque composition, using animal-specific data in an atherosclerotic mouse model. Tapered casts were placed around the right common carotid arteries (RCCA) of ApoE-/- mice. At 5, 7 and 9 weeks after cast placement, RCCA geometry was reconstructed using contrast-enhanced micro-CT...
March 2018: Royal Society Open Science
https://www.readbyqxmd.com/read/29657058/incremental-prognostic-value-of-coronary-and-systemic-atherosclerosis-after-myocardial-infarction
#7
Fredrik Calais, Maja Eriksson Östman, Pär Hedberg, Andreas Rosenblad, Jerzy Leppert, Ole Fröbert
BACKGROUND: The role of systemic atherosclerosis in myocardial infarction (MI) patients is not fully understood. We investigated the incremental prognostic value of coronary and systemic atherosclerosis after acute MI by estimating extra-cardiac artery disease (ECAD) and extent of coronary atherosclerosis. METHODS AND RESULTS: The study included 544 prospective MI patients undergoing coronary angiography. For all patients, the longitudinal coronary atherosclerotic extent, expressed as Sullivan extent score (SES) was calculated...
June 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29656494/oxidized-ldl-phagocytosis-during-foam-cell-formation-in-atherosclerotic-plaques-relies-on-a-pld2-cd36-functional-interdependence
#8
Ramya Ganesan, Karen M Henkels, Lucile E Wrenshall, Yasunori Kanaho, Gilbert Di Paolo, Michael A Frohman, Julian Gomez-Cambronero
The uptake of cholesterol carried by low-density lipoprotein (LDL) is tightly controlled in the body. Macrophages are not well suited to counteract the cellular consequences of excess cholesterol leading to their transformation into "foam cells," an early step in vascular plaque formation. We have uncovered and characterized a novel mechanism involving phospholipase D (PLD) in foam cell formation. Utilizing bone marrow-derived macrophages from genetically PLD deficient mice, we demonstrate that PLD2 (but not PLD1)-null macrophages cannot fully phagocytose aggregated oxidized LDL (Agg-Ox-LDL), which was phenocopied with a PLD2-selective inhibitor...
April 14, 2018: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/29656362/evaluation-of-animal-models-by-comparison-with-human-late-onset-alzheimer-s-disease
#9
Bu-Yeo Kim, Hye-Sun Lim, Yoonju Kim, Yu Jin Kim, Imhoi Koo, Soo-Jin Jeong
Despite many efforts to alleviate the pathological conditions of Alzheimer's disease (AD), effective therapeutic drugs have not been developed, mainly because of the lack of molecular information about AD and animal models. We observed the reciprocal regulation of AD-associated genes (AD genes) and their related functions. Upregulated AD genes were positioned in central regions in the protein-protein interaction network and were involved in inflammation and DNA repair pathways. Downregulated AD genes positioned in the periphery of the network were associated with metabolic pathways...
April 14, 2018: Molecular Neurobiology
https://www.readbyqxmd.com/read/29652660/cognitive-function-of-patients-with-rheumatoid-arthritis-is-associated-with-disease-activity-but-not-carotid-atherosclerotic-changes
#10
Ji Hyun Lee, Geun-Tae Kim, Yun-Kyung Kim, Seung-Geun Lee
OBJECTIVES: Although the relationship between atherosclerosis and cognitive impairment has been studied and replicated, whether cognitive deficits in RA can be attributed to atherosclerotic changes is not well understood. This study investigated cognitive function in patients with RA and evaluated whether cognitive function was affected by carotid arterial atherosclerosis. METHODS: We examined 70 RA patients and 40 healthy controls. RA activity was assessed by disease activity score with 28 joint-erythrocyte sedimentation rate (DAS28-ESR)...
April 13, 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29651957/serum-uric-acid-elevation-is-associated-to-arterial-stiffness-in-hypertensive-patients-with-metabolic-disturbances
#11
Agustin J Ramirez, Alejandra Ines Christen, Ramiro A Sanchez
INTRODUCTION: Chronic serum uric acid elevation (SUA) is known to be induced by dyslipidemia, hypertension, inflammation, and insulin resistance. Therefore, it has been associated with higher risk for coronary artery disease and cardiovascular mortality. Also, increased levels of SUA have been associated with regional arterial stiffness, assessed by pulse wave velocity (PWV). AIMS: To evaluate the relationships of PWV, SUA and different metabolic parameters in essential hypertensive patients...
April 13, 2018: Current Hypertension Reviews
https://www.readbyqxmd.com/read/29650781/anatomic-and-angiographic-analyses-of-ophthalmic-artery-collaterals-in-moyamoya-disease
#12
T Robert, G Cicciò, P Sylvestre, A Chiappini, A G Weil, S Smajda, C Chaalala, R Blanc, M Reinert, M Piotin, M W Bojanowski
BACKGROUND AND PURPOSE: Moyamoya disease is a progressive neurovascular pathology defined by steno-occlusive disease of the distal internal carotid artery and associated with the development of compensatory vascular collaterals. The etiology and exact anatomy of vascular collaterals have not been extensively studied. The aim of this study was to describe the anatomy of collaterals developed between the ophthalmic artery and the anterior cerebral artery in a Moyamoya population. MATERIALS AND METHODS: All patients treated for Moyamoya disease from 2004 to 2016 in 4 neurosurgical centers with available cerebral digital subtraction angiography were included...
April 12, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29650723/rivaroxaban-plus-aspirin-compared-with-aspirin-alone-reduced-cardiovascular-events-in-patients-with-stable-peripheral-or-carotid-artery-disease-but-increased-the-risk-of-major-bleeding
#13
REVIEW
https://www.readbyqxmd.com/read/29649504/tau-pathology-and-neurochemical-changes-associated-with-memory-dysfunction-in-an-optimised-murine-model-of-global-cerebral-ischaemia-a-potential-model-for-vascular-dementia
#14
Sabah Khan, Nadira Y Yuldasheva, Trevor F C Batten, Alasdair R Pickles, Katherine A B Kellett, Sikha Saha
Cerebral ischemia is known to be a major cause of death and the later development of Alzheimer's disease and vascular dementia. However, ischemia induced cellular damage that initiates these diseases remain poorly understood. This is primarily due to lack of clinically relevant models that are highly reproducible. Here, we have optimised a murine model of global cerebral ischaemia with multiple markers to determine brain pathology, neurochemistry and correlated memory deficits in these animals. Cerebral ischaemia in mice was induced by bilateral common carotid artery occlusion...
April 9, 2018: Neurochemistry International
https://www.readbyqxmd.com/read/29649307/bilateral-carotid-artery-stenosis-causes-unexpected-early-changes-in-brain-extracellular-matrix-and-blood-brain-barrier-integrity-in-mice
#15
Jill M Roberts, Michael E Maniskas, Gregory J Bix
Bilateral carotid artery stenosis (BCAS) is one experimental model of vascular dementia thought to preferentially impact brain white matter. Indeed, few studies report hippocampal and cortical pathology prior to 30 days post-stenosis; though it is unclear whether those studies examined regions outside the white matter. Since changes in the blood-brain barrier (BBB) permeability precede more overt brain pathology in various diseases, we hypothesized that changes within the BBB and/or BBB-associated extracellular matrix (ECM) could occur earlier after BCAS in the hippocampus, cortex and striatum and be a precursor of longer term pathology...
2018: PloS One
https://www.readbyqxmd.com/read/29643869/neurological-complications-are-avoidable-during-cabg
#16
Zulfiqar Haider, Anjum Jalal, Asif Rashid Alamgir, Irfan Rasheed
Objective: To review the incidence of stroke in patients undergoing CABG and the impact of a preventive strategy adopted at tertiary care unit of cardiac surgery. Methods: The data of all patients who underwent isolated CABG (N= 722) from July 2016 to August 2017 at Faisalabad Institute of Cardiology was retrieved for this retrospective study. All operations were done on cardiopulmonary bypass and cold blood cardioplegia. Numeric data was summarized as Mean ± Standard Deviation while categoric variables were summarized into frequency and percentage...
January 2018: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29643681/mismatch-in-brain-perfusion-and-metabolism-detected-with-99m-tc-hexamethyl-propylene-amine-oxime-single-photon-emission-computed-tomography-and-18-f-fluorodeoxyglucose-positron-emission-tomography-in-moyamoya-disease
#17
Justo Serrano Vicente, Luis Fernández Prudencio, José Rafael Infante Torre, Juan Ignacio Rayo Madrid
We report a 47-year-old woman who developed an ischemic stroke with diplopia and dysarthria. Emergency computed tomography (CT) showed no pathological findings, and magnetic resonance (MR) showed mild ischemic-degenerative lesions. MR angiography and angiogram showed severe stenosis of both internal carotid and main intracranial arteries with plenty collateral vessels with "puff of smoke" suggesting a moyamoya disease (MMD). Brain perfusion single-photon emission CT showed global diminished perfusion in the brain lobes and a marked relative hyperperfusion in the cerebellum...
April 2018: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/29643525/-association-between-chronic-periodontitis-and-carotid-intima-media-thickness-of-middle-aged-and-older-adults-in-shijingshan-community-of-beijing
#18
Y Liu, Q X Luan
OBJECTIVE: To investigate the relationship between periodontal disease and subclinical atherosclerosis in middle-aged and older adults in Shijingshan community of Beijing. METHODS: In 2005-2010, a total of 830 middle-aged and older adults were recruited from Shijingshan community of Beijing, who were divided into two groups by severity of periodontitis. A questionnaire, periodontal examination, blood biochemical examination, carotid intima-media thickness (CIMT), including common carotid artery (CCA-IMT), internal carotid artery (ICA-IMT) and carotid bifurcation (CB-IMT), were measured of each subject...
April 18, 2018: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29628950/safety-assessment-of-endovascular-treatment-of-cerebral-aneurysms-in-patients-with-fibromuscular-dysplasia
#19
Matthew T Bender, Christopher Hurtado, Bowen Jiang, Jessica K Campos, Judy Huang, Rafael J Tamargo, Li-Mei Lin, Alexander L Coon, Geoffrey P Colby
Background: The prevalence of cerebral aneurysms is increased in fibromuscular dysplasia (FMD). The presence of FMD may serve as discouragement to elective endovascular aneurysm treatment. Outcomes of endovascular intervention for aneurysms through vessels affected by FMD have not been reported. Methods: A prospectively maintained database of patients undergoing intracranial embolization was reviewed for patients with FMD who underwent endovascular aneurysm treatment...
February 2018: Interventional Neurology
https://www.readbyqxmd.com/read/29627942/orthostatic-hypotension-acutely-impairs-executive-functions-in-parkinson-s-disease
#20
Michela Sforza, Francesca Assogna, Domiziana Rinaldi, Giuliano Sette, Stefania Tagliente, Francesco E Pontieri
Orthostatic hypotension is a frequent non-motor symptom of Parkinson's disease, with negative prognostic role on cognitive functions. Here we measured the acute effects of orthostatic hypotension on executive functions in Parkinson's disease patients devoid of hypertension, carotid artery stenosis, and significant chronic cerebrovascular pathology. Measurements were carried out during regular visits in outpatient setting. Twenty-eight Parkinson's disease patients were recruited and studied along scheduled outpatient visits...
April 7, 2018: Neurological Sciences
keyword
keyword
10506
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"