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Carotid artery disease

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https://www.readbyqxmd.com/read/29913294/association-between-champagne-bottle-neck-sign-of-internal-carotid-artery-and-ipsilateral-hemorrhagic-stroke-in-patients-with-moyamoya-disease
#1
Jian Wang, Gong Chen, Yongbo Yang, Bing Zhang, Zhongzhi Jia, Peiyuan Gu, Dong Wei, Jing Ji, Weixing Hu, Xihai Zhao
OBJECTIVE: To assess the association between champagne bottle neck sign (CBNS) in carotid artery and intracranial hemorrhage in patients with moyamoya disease (MMD). METHODS: From January 2016 to December 2017, a total of 76 consecutive patients with MMD without definite risk factors associated intracranial hemorrhage who underwent preoperative angiography were included in this retrospective study. CBNS was defined as luminal diameter of internal carotid artery (ICA)/common carotid artery (CCA) ≤ 0...
June 15, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29913284/effect-sizes-of-bold-cvr-resting-state-signal-fluctuations-and-time-delay-measures-for-the-assessment-of-hemodynamic-impairment-in-carotid-occlusion-patients
#2
Jill B De Vis, Alex A Bhogal, Jeroen Hendrikse, Esben T Petersen, Jeroen C W Siero
BACKGROUND AND PURPOSE: The BOLD signal amplitude as a response to a hypercapnia stimulus is commonly used to assess cerebrovascular reserve. Despite recent advances, the implementation remains cumbersome and alternative ways to assess hemodynamic impairment are desirable. Resting-state BOLD signal fluctuations (rsBOLD) have been proposed however data on its sensitivity and dependence on baseline venous cerebral blood volume (vCBV) is limited. The primary aim of this study was to compare the effect sizes of resting-state and hypercapnia induced BOLD signal changes in the detection of hemodynamic impairment...
June 15, 2018: NeuroImage
https://www.readbyqxmd.com/read/29911252/progress-in-moyamoya-disease
#3
REVIEW
Shuling Shang, Da Zhou, Jingyuan Ya, Sijie Li, Qi Yang, Yuchuan Ding, Xunming Ji, Ran Meng
Moyamoya disease is characterized by progressive stenosis or occlusion of the intracranial portion of the internal carotid artery and their proximal branches, resulting in ischemic or hemorrhagic stroke with high rate of disability and even death. So far, available treatment strategies are quite limited, and novel intervention method is being explored. This review encapsulates current advances of moyamoya disease on the aspects of epidemiology, etiology, clinical features, imaging diagnosis and treatment. In addition, we also bring forward our conjecture, which needs to be testified by future research...
June 18, 2018: Neurosurgical Review
https://www.readbyqxmd.com/read/29911036/assessment-of-cardiovascular-risk-in-natural-and-surgical-menopause
#4
S Zafar Abbas, Vijayata Sangawan, Asim Das, Anil Kumar Pandey
Background: Menopause is associated with increased cardiovascular disease (CVD) risk. Arterial stiffness, a biomarker of vascular aging, increases the risk for CVD. Aims and Objectives: The study was aimed to determine whether menopause is associated with arterial stiffness amongst natural and surgical menopausal women. Materials and Methods: We conducted a cross-sectional study amongst natural postmenopausal women, with Surgical menopause and Premenopausal...
March 2018: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29908694/arterial-stiffness-in-ckd-a-review
#5
REVIEW
Raymond R Townsend
This narrative review summarizes a decade of experience examining the cross-sectional and longitudinal relationships of arterial stiffness, as assessed using carotid-femoral pulse wave velocity, with outcomes in patients with chronic kidney disease enrolled in the Chronic Renal Insufficiency Cohort. Our goal is to review the importance of the pulse wave contour and pulse wave velocity and present data on the reproducibility of pulse wave velocity measurements, determinants of pulse wave velocity, and the relationship that velocity measurements have with longitudinal kidney and cardiovascular outcomes...
June 13, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29905566/-evaluation-of-neuroprotective-activity-of-complex-impact-of-magnesium-of-sulfate-lamotrygine-and-n-acetylcysteine-under-conditions-of-combined-normobaric-hypoxia-with-ligation-of-right-carotid-artery-in-rats
#6
M Samsonia, M Kandelaki, N Baratashvili
Cerebrovascular diseases of ischemic origin still remain the leading cause of death and disability of the population. In acute cerebral discirculation conditions, anaerobic glycolysis is activated, ATP formation rate decreases, the ion pumps work is disrupted and superoxide radicals are formed. Eventually, ionic asymmetry leads to the cytotoxic and vasogenic brain edema. Therefore, it is extremely important to induce simultaneous (complex) effect of medications on the key mechanisms of neuronal damage in process of survival of brain cells during acute ischemic stroke...
May 2018: Georgian Medical News
https://www.readbyqxmd.com/read/29904040/a-pilot-trial-to-examine-the-changes-in-carotid-arterial-inflammation-in-renal-transplant-recipients-as-assessed-by-18f-fluorodeoxyglucose-18f-fdg-positron-emission-tomography-computed-tomography-pet-ct
#7
Hye Eun Yoon, Yaeni Kim, Sang Dong Kim, Jin Kyoung Oh, Yong-An Chung, Seok Joon Shin, Chul Woo Yang, Suk Min Seo
BACKGROUND Inflammatory activity of the artery can be assessed by measuring 18F-fluorodeoxyglucose (18F-FDG) uptake with positron emission tomography computed tomography (PET/CT). Improvement in vascular function after renal transplantation has been reported, but no studies have used 18F-FDG PET/CT to examine the changes in vascular inflammation. This study investigated the changes in the inflammatory activity in the carotid artery after renal transplantation in patients with chronic kidney disease (CKD). MATERIAL AND METHODS 18F-FDG PET/CT was performed before and at 4 months after transplantation...
June 15, 2018: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/29903736/limited-macrophage-positional-dynamics-in-progressing-or-regressing-murine-atherosclerotic-plaques
#8
Jesse W Williams, Catherine Martel, Stephane Potteaux, Ekaterina Esaulova, Molly A Ingersoll, Andrew Elvington, Brian T Saunders, Li-Hao Huang, Andreas J Habenicht, Bernd H Zinselmeyer, Gwendalyn J Randolph
OBJECTIVE: Macrophages play important roles in the pathogenesis of atherosclerosis, but their dynamics within plaques remain obscure. We aimed to quantify macrophage positional dynamics within progressing and regressing atherosclerotic plaques. APPROACH AND RESULTS: In a stable intravital preparation, large asymmetrical foamy macrophages in the intima of carotid artery plaques were sessile, but smaller rounded cells nearer plaque margins, possibly newly recruited monocytes, mobilized laterally along plaque borders...
June 14, 2018: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/29902198/intimal-and-medial-arterial-changes-defined-by-ultra-high-frequency-ultrasound-response-to-changing-risk-factors-in-children-with-chronic-kidney-disease
#9
Frida Dangardt, Marietta Charakida, Scott Chiesa, Devina Bhowruth, Alicja Rapala, Daniela Thurn, Franz Schaefer, John Deanfield, Rukshana Shroff
BACKGROUND: Patients with chronic kidney disease (CKD) are exposed to both traditional 'Framingham' and uremia related cardiovascular risk factors that drive atherosclerotic and arteriosclerotic disease, but these cannot be differentiated using conventional ultrasound. We used ultra-high-frequency ultrasound (UHFUS) to differentiate medial thickness (MT) from intimal thickness (IT) in CKD patients, identify their determinants and monitor their progression. METHODS: Fifty-four children and adolescents with CKD and 12 healthy controls underwent UHFUS measurements using 55-70MHz transducers in common carotid and dorsal pedal arteries...
2018: PloS One
https://www.readbyqxmd.com/read/29901637/extracranial-intracranial-bypass-in-medial-sphenoid-ridge-meningioma-associated-with-severe-stenosis-of-the-intracranial-segments-of-the-internal-carotid-artery-a-case-report
#10
Yabo Huang, Zhong Wang, Qingdong Han
RATIONALE: Tumor resection and extracranial-intracranial bypass concerning medial sphenoid ridge meningioma associated with severe stenosis of the internal carotid artery (ICA) of intracranial segments has been rarely presented. Effective treatment as to the complex lesions may be complicated. Tumor resection and cerebrovascular protection should be both taken into consideration. PATIENT CONCERNS: We presented one case of medial sphenoid ridge meningioma associated with severe stenosis of the internal carotid artery of intracranial segments...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29901510/carotid-artery-tortuosity-index-is-associated-with-the-need-for-early-aortic-root-replacement-in-patients-with-loeys-dietz-syndrome
#11
Linda C Chu, Reham R Haroun, Robert J Beaulieu, James H Black, Harry C Dietz, Elliot K Fishman
OBJECTIVE: This study aimed to determine if carotid arterial tortuosity represents a marker of disease severity in Loeys-Dietz syndrome (LDS). METHODS: Fifty-four 54 LDS patients (mean age, 17.0 years) who underwent computed tomogram angiography from January 2004 to December 2013 were retrospectively identified. Carotid artery tortuosity index (CATI) was calculated from computed tomogram angiography. Clinical variables were obtained from the medical records. Relationship between CATI and need for aortic root replacement was evaluated with Cox proportional hazard model and Kaplan-Meier analysis...
June 12, 2018: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/29900985/cerebral-blood-flow-volume-using-color-duplex-sonography-in-patients-with-fibromyalgia-syndrome
#12
Arzu Kaya, Gürkan Akgöl, Arif Gülkesen, Ahmet Kürşad Poyraz, Tülay Yildirim, Murad Atmaca
Objectives: This study aims to evaluate cerebral blood flow using color duplex Doppler ultrasonography in patients with fibromyalgia syndrome (FMS). Patients and methods: The study included 30 female patients with FMS (mean age 42.3 years; range 22 to 59 years) and 30 female healthy controls (mean age 39.6 years; range 22 to 56 years). Color duplex Doppler ultrasonography imaging was performed with an EPIQ 5 unit equipped with a multi-frequency linear probe (3-12 MHz) in the supine position...
March 2018: Archives of Rheumatology
https://www.readbyqxmd.com/read/29898836/impact-of-polyvascular-disease-on-patients-with-atrial-fibrillation-insights-from-rocket-af
#13
Sean T Chen, Anne S Hellkamp, Richard C Becker, Scott D Berkowitz, Günter Breithardt, Keith A A Fox, Werner Hacke, Jonathan L Halperin, Graeme J Hankey, Kenneth W Mahaffey, Christopher C Nessel, Jonathan P Piccini, Daniel E Singer, Manesh R Patel
BACKGROUND: We investigated the impact of polyvascular disease in patients enrolled in ROCKET AF. METHODS: Cox regression models were used to assess clinical outcomes and treatment effects of rivaroxaban compared with warfarin in patients with atrial fibrillation and coronary, peripheral, or carotid artery disease, or any combination of the 3. RESULTS: A total of 655 (4.6%) patients had polyvascular disease (≥2 disease locations), and 3,391 (23...
June 2018: American Heart Journal
https://www.readbyqxmd.com/read/29895966/a-dual-modality-hybrid-imaging-system-harnesses-radioluminescence-and-sound-to-reveal-molecular-pathology-of-atherosclerotic-plaques
#14
Raiyan T Zaman, Siavash Yousefi, Steven R Long, Toshinobu Saito, Michael Mandella, Zhen Qiu, Ruimin Chen, Christopher H Contag, Sanjiv S Gambhir, Frederick T Chin, Butras T Khuri-Yakub, Michael V McConnell, K Kirk Shung, Lei Xing
Atherosclerosis is a progressive inflammatory condition caused by an unstable lesion, called thin-cap fibro atheromata (TCFA) that underlies coronary artery disease (CAD)-one of the leading causes of death worldwide. Therefore, early clinical diagnosis and effective risk stratification is important for CAD management as well as preventing progression to catastrophic events. However, early detection could be difficult due to their small size, motion, obscuring 18 F-FDG uptake by adjacent myocardium, and complex morphological/biological features...
June 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29895600/stroke-and-cardiovascular-outcomes-in-patients-with-carotid-disease-undergoing-transcatheter-aortic-valve-replacement
#15
Ajar Kochar, Zhuokai Li, J Kevin Harrison, G Chad Hughes, Vinod H Thourani, Michael J Mack, Roland A Matsouaka, David J Cohen, Eric D Peterson, W Schuyler Jones, Sreekanth Vemulapalli
BACKGROUND: Stroke is a serious complication of both transcatheter aortic valve replacement (TAVR) and carotid artery disease (CD). The implications of CD in patients undergoing TAVR are unclear. METHODS AND RESULTS: The Society of Thoracic Surgeons and American College of Cardiology Transcatheter Valve Therapies Registry, consisting of data from consecutive US TAVR cases during the years 2013 to 2015, was linked to Medicare claims data to ascertain 30-day and 1-year cumulative incidence rates of stroke and all-cause mortality...
June 2018: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29889690/comparison-between-visual-and-numerical-metrics-for-the-evaluation-of-patients-with-takayasu-arteritis-with-18f-fdg-pet
#16
Berivan Emsen, Khadija Benali, Besma Mahida, Delphine Larivière, Dominique Le Guludec, Thomas Papo, Karim Sacre, Fabien Hyafil
INTRODUCTION: The choice of metrics for defining active Takayasu arteritis (TAK) using fluorine-18-fluorodeoxyglucose (F-FDG)-PET remains controversial. OBJECTIVE: The aim of this study was to compare in the same patients the diagnostic performance for the detection of active TAK of different metrics applied for the quantification of vascular F-FDG uptake with PET. PATIENTS AND METHODS: Overall, 62 PET acquisitions were performed 90 min after F-FDG injection in 15 patients with TAK and analyzed retrospectively...
June 8, 2018: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/29888621/the-relationship-between-aspirin-resistance-and-carotid-imaging-in-young-patients-with-st-segment-elevated-myocardial-infarction-a-cross-sectional-study
#17
Mustafa Umut Somuncu, Ali Riza Demir, Huseyin Karakurt, Nail Guven Serbest, Belma Kalayci, Umit Bulut, Seda Tukenmez Karakurt
The presence of carotid atherosclerosis accompanied by coronary artery disease is associated with poor prognosis. A subset of patients who take aspirin continue to have recurrent cardiovascular events, which may be due to aspirin resistance (AR). Also, carotid plaques may cause turbulent flow which in turn may lead to platelet activation and poor antiplatelet response. In our study, we aimed to show the prevalence of AR and its relationship between high-risk carotid images in young patients with ST-segment elevated myocardial infarction (STEMI)...
January 1, 2018: Clinical and Applied Thrombosis/hemostasis
https://www.readbyqxmd.com/read/29887510/use-of-a-folded-extended-vertical-lower-trapezius-island-myocutaneous-flap-to-repair-large-pharyngocutaneous-fistulae-developing-after-salvage-total-laryngectomy
#18
Z-Q Huang, B Zhou, W-L Chen, J-L Zhong, Y Wang
The purpose of this study was to evaluate the outcomes of surgery involving the use of folded trapezius flaps to repair large pharyngocutaneous fistulae (PCFs) developing after salvage total laryngectomy. Folded extended vertical lower trapezius island myocutaneous flaps (TIMFs) were created to repair large PCFs that developed after salvage total laryngectomy in eight patients. The maximum fistula dimension was 4.5×3.0cm and the minimum was 2.0×1.8cm. The skin paddle of the extended vertical TIMF ranged from 5cm to 9cm in width and 10cm to 23cm in length...
June 7, 2018: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29886715/recent-advances-in-primary-and-secondary-prevention-of-atherosclerotic-stroke
#19
Georgios Tsivgoulis, Apostolos Safouris, Dong-Eog Kim, Andrei V Alexandrov
Atherosclerosis is a major cause of ischemic stroke that can be effectively prevented with appropriate lifestyle modifications and control of cardiovascular risk factors. Medical advances in recent years along with aggressive cardiovascular risk factor modifications have resulted in decreased recurrence rates of atherosclerotic stroke. Non-statin lipid-lowering molecules have recently shown clinical benefit and are recommended for very high-risk patients to reduce their risk of stroke. Aggressive hypertension treatment is crucial to reduce atherosclerotic stroke risk...
May 2018: Journal of Stroke
https://www.readbyqxmd.com/read/29886218/concomitant-hybrid-arch-vessel-reconstruction-and-intracranial-clot-retrieval-in-takayasu-s-arteritis-presenting-with-acute-cerebral-ischaemia-a-case-report
#20
Leonard Shan, David Goh, Timothy Wagner
INTRODUCTION: Type 1 Takayasu's arteritis (TA) predominantly affects the supra-aortic branches. Occlusive disease can cause catastrophic complications such as stroke and death. Open and endovascular techniques of revascularisation are described for extracranial disease. There is currently no default choice of surgical intervention. Furthermore, the management of distal intracranial complications has not been described. PRESENTATION OF CASE: A 25-year-old lady with known TA on immunosuppression presents with acute left middle cerebral artery (MCA) stroke...
June 7, 2018: Annals of Vascular Surgery
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