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European Urological Association

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https://www.readbyqxmd.com/read/28336078/what-is-the-negative-predictive-value-of-multiparametric-magnetic-resonance-imaging-in-excluding-prostate-cancer-at-biopsy-a-systematic-review-and-meta-analysis-from-the-european-association-of-urology-prostate-cancer-guidelines-panel
#1
REVIEW
Paul C Moldovan, Thomas Van den Broeck, Richard Sylvester, Lorenzo Marconi, Joaquim Bellmunt, Roderick C N van den Bergh, Michel Bolla, Erik Briers, Marcus G Cumberbatch, Nicola Fossati, Tobias Gross, Ann M Henry, Steven Joniau, Theo H van der Kwast, Vsevolod B Matveev, Henk G van der Poel, Maria De Santis, Ivo G Schoots, Thomas Wiegel, Cathy Yuhong Yuan, Philip Cornford, Nicolas Mottet, Thomas B Lam, Olivier Rouvière
CONTEXT: It remains unclear whether patients with a suspicion of prostate cancer (PCa) and negative multiparametric magnetic resonance imaging (mpMRI) can safely obviate prostate biopsy. OBJECTIVE: To systematically review the literature assessing the negative predictive value (NPV) of mpMRI in patients with a suspicion of PCa. EVIDENCE ACQUISITION: The Embase, Medline, and Cochrane databases were searched up to February 2016. Studies reporting prebiopsy mpMRI results using transrectal or transperineal biopsy as a reference standard were included...
March 20, 2017: European Urology
https://www.readbyqxmd.com/read/28317247/establishing-the-pathways-and-indications-for-performing-isotope-bone-scans-in-newly-diagnosed-intermediate-risk-localised-prostate-cancer-results-from-a-large-contemporaneous-cohort
#2
Gokul Vignesh KandaSwamy, Adam Bennett, Krishna Narahari, Owen Hughes, John Rees, Howard Kynaston
OBJECTIVE: To establish the pattern of isotope bone scan (BS) positivity in a large contemporaneous cohort of newly diagnosed localised prostate cancer (PCa) patients and compare with the European Association of Urology (EAU) guidelines. BACKGROUND: Imaging guidelines and clinical practice of using BS to stage newly diagnosed patients with intermediate risk (IR) localised PCa are not uniform in the literature. PATIENTS AND METHODS: All newly diagnosed PCa patients were discussed in a specialist multidisciplinary team (sMDT) meeting and were prospectively entered in a database...
March 20, 2017: BJU International
https://www.readbyqxmd.com/read/28285790/diagnosis-and-treatment-for-clinically-localized-prostate-cancer-adherence-to-the-european-association-of-urology-clinical-guidelines-in-a-nationwide-population-based-study-gescap-group
#3
F Gómez-Veiga, A Rodríguez-Antolín, B Miñana, C Hernández, J F Suárez, J M Fernández-Gómez, M Unda, J Burgos, A Alcaraz, P Rodríguez, R Medina, J Castiñeiras, C Moreno, E Pedrosa, J M Cózar
OBJECTIVE: To assess the adherence to European Association of Urology (EAU) guidelines in the management of prostate cancer (PCa) in Spain. PATIENTS AND METHODS: Epidemiological, population-based, study including a national representative sample of 3,918 incident patients with histopathological confirmation during 2010; 95% of the patient's sample was followed up for at least one year. Diagnosis along with treatment related variables (for localized PCa -low, intermediate, high and locally-advanced by D'Amico risk stratification) was recorded...
March 9, 2017: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/28265307/antibiotic-prophylaxis-for-prevention-of-urinary-tract-infections-in-prenatal-hydronephrosis-an-updated-systematic-review
#4
REVIEW
Bethany Easterbrook, John-Paul Capolicchio, Luis H Braga
INTRODUCTION: While continuous antibiotic prophylaxis (CAP) is currently recommended to prevent urinary tract infections (UTIs) in infants with prenatal hydronephrosis (HN), this recommendation is not evidence-based. The objective of this study was to systematically determine whether CAP reduces UTIs in the HN population. METHODS: Applicable trials were identified through an electronic search of MEDLINE (1946-2015), EMBASE (1980-2016), CINAHL (1982-2016), and CENTRAL (1993-2016) and through a hand search of American Urological Association (AUA) (2012-2015) and European Society for Pediatric Urology (ESPU) (2012-2015) abstracts, as well as reference lists of included trials...
January 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28249799/european-association-of-urology-position-statement-on-the-role-of-the-urologist-in-the-management-of-male-hypogonadism-and-testosterone-therapy
#5
EDITORIAL
Vincenzo Mirone, Frans Debruyne, Gert Dohle, Andrea Salonia, Nikolaos Sofikitis, Paolo Verze, Mikkel Fode, Christopher Chapple
Testosterone is a crucial sex hormone important for the health and development of men of all ages. It plays a role in the integrity and maintaining the function of several systems and organs. Testosterone deficiency is linked to a number of signs and symptoms potentially affecting every man in his complexity and masculinity, and is therefore of strong urological interest. For this reason, urologists should attach importance to the need for knowledge, vocational education, and training in this specific area.
February 26, 2017: European Urology
https://www.readbyqxmd.com/read/28247659/-prevalence-and-risk-factors-for-urinary-incontinence-in-women-living-in-the-south-priaralye-region
#6
A A Gaibullaev, G T Iskandarova, A A Abdurizaev
OBJECTIVE: To estimate prevalence and types of urinary incontinence (UI) among women living in the South Priaralye region, and to analyze risk factors associated with UI. MATERIALS AND METHODS: The population-based study was conducted by nested-typological method. Analysis was carried out on the data of 1487 women collected by a standard ICIQ-SF questionnaire, an assessment tool for female urinary incontinence recommended by the European Association of Urology. RESULTS: The study showed that the prevalence of UI among women aged 18 years and older in the South Priaralye region was 27%...
April 2016: Urologii︠a︡
https://www.readbyqxmd.com/read/28247325/medical-expulsive-therapy-worthwhile-or-wishful-thinking
#7
REVIEW
Tad Kroczak, Kenneth T Pace, Jason Y Lee
PURPOSE OF REVIEW: We set out to provide an overview of the most recent evidence for medical expulsive therapy (MET). Conflicting level 1 evidence for and against the use of MET has been published. RECENT FINDINGS: The largest double-blind randomized control trial (1110 patients) comparing placebo, tamsulosin, and nifedipine found no benefit for MET in preventing the need for secondary intervention. A recent meta-analysis of 55 randomized trials using alpha-blockers suggests that no benefit is seen with smaller ureteric calculi, but patients with larger ureteric calculi experience shorter times to stone passage, fewer episodes of pain, require less surgical intervention, and fewer hospital admissions...
April 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28237786/tract-sizes-in-miniaturized-percutaneous-nephrolithotomy-a-systematic-review-from-the-european-association-of-urology-urolithiasis-guidelines-panel
#8
Yasir Ruhayel, Abdulkadir Tepeler, Saeed Dabestani, Steven MacLennan, Aleš Petřík, Kemal Sarica, Christian Seitz, Andreas Skolarikos, Michael Straub, Christian Türk, Yuhong Yuan, Thomas Knoll
CONTEXT: Miniaturized instruments for percutaneous nephrolithotomy (PNL), utilizing tracts sized ≤22 Fr, have been developed in an effort to reduce the morbidity and increase the efficiency of stone removal compared with standard PNL (>22 Fr). OBJECTIVE: We systematically reviewed all available evidence on the efficacy and safety of miniaturized PNL for removing renal calculi. EVIDENCE ACQUISITION: The review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses statement...
February 22, 2017: European Urology
https://www.readbyqxmd.com/read/28211236/london-welcomes-the-european-association-of-urology-eau
#9
EDITORIAL
Christopher R Chapple
No abstract text is available yet for this article.
March 2017: BJU International
https://www.readbyqxmd.com/read/28074261/perioperative-chemotherapy-in-upper-tract-urothelial-carcinoma-a-comprehensive-review
#10
REVIEW
Atiqullah Aziz, Jakub Dobruch, Kees Hendricksen, Luis A Kluth, Andrea Necchi, Aidan Noon, Michael Rink, Florian Roghmann, Roland Seiler, Paolo Gontero, Wassim Kassouf, Shahrokh F Shariat, Evanguelos Xylinas
PURPOSE: To evaluate the role of neoadjuvant (NAC) and adjuvant chemotherapy (AC) in patients with upper tract urothelial carcinoma (UTUC) treated with radical nephroureterectomy (RNU). METHODS: A comprehensive review of the current literature was performed searching for all studies investigating NAC and AC in UTUC in MEDLINE and https://clinicaltrials.gov , prior to April 2016. The following keywords were used: "ureteral neoplasms," "urothelium," "ureter," "upper tract urothelial," "chemotherapy," "adjuvant," "neoadjuvant" and relevant variants...
January 10, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28058776/guideline-of-guidelines-non-muscle-invasive-bladder-cancer
#11
LETTER
Solomon L Woldu, Aditya Bagrodia, Yair Lotan
Non-muscle-invasive bladder cancer (NMIBC) represents the vast majority of bladder cancer diagnoses, but this definition represents a spectrum of disease with a variable clinical course, notable for significant risk of recurrence and potential for progression. Management involves risk-adapted strategies of cystoscopic surveillance and intravesical therapy with the goal of bladder preservation when safe to do so. Multiple organizational guidelines exist to help practitioners manage this complicated disease process, but adherence to management principles among practising urologists is reportedly low...
March 2017: BJU International
https://www.readbyqxmd.com/read/28051764/the-use-of-fibrin-sealant-during-non-emergency-surgery-a-systematic-review-of-evidence-of-benefits-and-harms
#12
Steven J Edwards, Fay Crawford, Michelle Helena van Velthoven, Andrea Berardi, George Osei-Assibey, Mariana Bacelar, Fatima Salih, Victoria Wakefield
BACKGROUND: Fibrin sealants are used in different types of surgery to prevent the accumulation of post-operative fluid (seroma) or blood (haematoma) or to arrest haemorrhage (bleeding). However, there is uncertainty around the benefits and harms of fibrin sealant use. OBJECTIVES: To systematically review the evidence on the benefits and harms of fibrin sealants in non-emergency surgery in adults. DATA SOURCES: Electronic databases [MEDLINE, EMBASE and The Cochrane Library (including the Cochrane Database of Systematic Reviews, the Database of Abstracts of Reviews of Effects, the Health Technology Assessment database and the Cochrane Central Register of Controlled Trials)] were searched from inception to May 2015...
December 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/27986369/updated-european-association-of-urology-guidelines-regarding-adjuvant-therapy-for-renal-cell-carcinoma
#13
Axel Bex, Laurence Albiges, Börje Ljungberg, Karim Bensalah, Saeed Dabestani, Rachel H Giles, Fabian Hofmann, Milan Hora, Markus A Kuczyk, Thomas B Lam, Lorenzo Marconi, Axel S Merseburger, Michael Staehler, Alessandro Volpe, Thomas Powles
The European Association of Urology Renal Cell Carcinoma (RCC) guidelines panel updated their recommendation on adjuvant therapy in unfavourable, clinically nonmetastatic RCC following the recently reported results of a second randomised controlled phase 3 trial comparing 1-yr sunitinib to placebo for high-risk RCC after nephrectomy (S-TRAC). On the basis of conflicting results from the two available studies, the panel rated the quality of the evidence, the harm-to-benefit ratio, patient preferences, and costs...
December 13, 2016: European Urology
https://www.readbyqxmd.com/read/27964825/carbon-dioxide-laser-treatment-of-penile-intraepithelial-neoplasia
#14
Abdullah Zreik, Matthew Rewhorn, Ross Vint, Rehan Khan, David Hendry
INTRODUCTION & OBJECTIVE: The non-invasive nature of penile intraepithelial neoplasia (PeIN) allows for curative penile sparing therapy and is recommended, in their guidelines, by the European Association of Urology (EAU). Treatment options include topical chemotherapy, immunotherapy, laser treatment, photodynamic therapy and surgical excision. Our primary aim was to evaluate the outcome of carbon dioxide (CO2) laser treatment of penile intraepithelial neoplasia. METHODS: A retrospective review of 47 patients who underwent CO2 laser ablation of PeIN, from May 2008 to June 2015, in our tertiary referral centre was performed...
December 7, 2016: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/27914898/conflict-of-evidence-resolving-discrepancies-when-findings-from-randomized-controlled-trials-and-meta-analyses-disagree
#15
REVIEW
Richard J Sylvester, Steven E Canfield, Thomas B L Lam, Lorenzo Marconi, Steven MacLennan, Yuhong Yuan, Graeme MacLennan, John Norrie, Muhammad Imran Omar, Harman M Bruins, Virginia Hernández, Karin Plass, Hendrik Van Poppel, James N'Dow
CONTEXT: Clinicians and treatment guideline developers are faced with a dilemma when the results of a new, large, well-conducted randomized controlled trial (RCT) are in direct conflict with the results of a previous systematic review (SR) and meta-analysis (MA). OBJECTIVE: To explore and discuss possible reasons for disagreement in results from SRs/MAs and RCTs and to provide guidance to clinicians and guideline developers for making well-informed treatment decisions and recommendations in the face of conflicting data...
November 30, 2016: European Urology
https://www.readbyqxmd.com/read/27906777/asymptomatic-bacteriuria-to-screen-or-not-to-screen-and-when-to-treat
#16
Tommaso Cai, Bela Koves, Truls E Bjerklund Johansen
PURPOSE OF REVIEW: Asymptomatic bacteriuria (ABU) is a common clinical condition that often leads to unnecessary treatment. The purpose of this review is to outline and evaluate the most recent literature on the management of ABU. RECENT FINDINGS: The role of ABU management has been evaluated in several patient subgroups: healthy patients without identified risk factors, pregnant women, postmenopausal women, women with recurrent UTI, patients with diabetes, elderly institutionalized patients, patients with renal transplants, patients with indwelling catheters and prior to surgery...
March 2017: Current Opinion in Urology
https://www.readbyqxmd.com/read/27894612/influence-of-social-networks-on-congresses-of-urological-societies-and-associations-results-of-the-81th-national-congress-of-the-spanish-urological-association
#17
J Gómez-Rivas, M E Rodríguez-Socarrás, L Tortolero-Blanco, M Garcia-Sanz, M Alvarez-Maestro, M J Ribal, M Cózar-Olmo
OBJECTIVE: To measure social network activity during the 81th National Congress of the Spanish Urological Association (AEU) and to compare it with the activity during other congresses of national and international urological associations. MATERIAL AND METHODS: We designed and registered the official hashtag #AEU16 for the 81(th) National Congress of the AEU on the Symplur website. The following measurements were recorded: number of participants, number of tweets, tweets by participant, tweets per hour and views...
November 25, 2016: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/27866870/commentary-to-management-of-undescended-testes-european-association-of-urology-european-society-for-paediatric-urology-guidelines
#18
Thomas F Kolon
No abstract text is available yet for this article.
December 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/27860090/guideline-of-guidelines-priapism
#19
REVIEW
Asif Muneer, David Ralph
No abstract text is available yet for this article.
November 14, 2016: BJU International
https://www.readbyqxmd.com/read/27773650/is-preoperative-assessment-and-treatment-of-asymptomatic-bacteriuria-necessary-for-reducing-the-risk-of-postoperative-symptomatic-urinary-tract-infections-after-urologic-surgical-procedures
#20
Tommaso Cai, Paolo Verze, Alessandro Palmieri, Mauro Gacci, Paolo Lanzafame, Gianni Malossini, Gabriella Nesi, Gernot Bonkat, Florian M E Wagenlehner, Vincenzo Mirone, Riccardo Bartoletti, Truls E Bjerklund Johansen
OBJECTIVE: To evaluate whether it is always necessary to test for the presence of asymptomatic bacteriuria (AB) in patients undergoing urologic surgical procedures, and if present, whether to treat AB with antimicrobial prophylaxis. MATERIALS AND METHODS: All patients who underwent urologic surgical procedures from December 2008 to October 2013 in a tertiary referral urologic center were considered for this study. All patients received antimicrobial prophylaxis in line with European Association of Urology guidelines on urologic infections...
January 2017: Urology
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