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tetralogy of fallot

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https://www.readbyqxmd.com/read/29050815/right-ventricular-outflow-tract-reintervention-after-primary-tetralogy-of-fallot-repair-in-neonates-and-young-infants
#1
Shyamasundar Balasubramanya, David Zurakowski, Michele Borisuk, Aditya K Kaza, Sitaram M Emani, Pedro J Del Nido, Christopher W Baird
OBJECTIVE: To assess the outcomes following primary tetralogy of Fallot (TOF) repair in neonates and young infants with pulmonary stenosis (PS) and pulmonary atresia and compare differences in reintervention on the right ventricular outflow tract (RVOT) among those undergoing valve sparing repair (VSR), transannular RVOT patch (TAP), and right ventricle-to-pulmonary artery (RV-PA) conduit surgeries. METHODS: Data were collected retrospectively in 101 patients who underwent TOF repair over a 10-year period between January 2005 and September 2015...
September 19, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29049707/influence-of-staged-repair-and-primary-repair-on-outcomes-in-patients-with-complete-atrioventricular-septal-defect-and-tetralogy-of-fallot-a-systematic-review-and-meta-analysis
#2
Evgeniy Lenko, Yuriy Kulyabin, Alexey Zubritskiy, Yuriy Gorbatykh, Yuriy Naberukhin, Nataliya Nichay, Alexander Bogachev-Prokophiev, Alexander Karaskov
OBJECTIVES: Complete atrioventricular septal defect with tetralogy of Fallot is a rare congenital heart disease. The combination of these lesions occurs in about 1% of all patients with atrioventricular canal defects and in 5-6% of patients with tetralogy of Fallot. To assess the influence of surgical strategy on the survival and reintervention rate for the left atrioventricular valve and right ventricular outflow tract. METHODS: We analyzed all related studies since 1986...
August 25, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049668/one-stage-definitive-repair-of-complete-atrioventricular-septal-defect-and-pulmonary-atresia-with-major-aortopulmonary-collateral-arteries
#3
Yujiro Ide, Masaya Murata, Hiroki Ito, Kisaburo Sakamoto
Pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries is considered the most severe end of the tetralogy of Fallot spectrum, whereas complete atrioventricular septal defect associated with tetralogy of Fallot is a rare congenital defect. However, the combination of pulmonary atresia, major aortopulmonary collateral artery and complete atrioventricular septal defect is extremely rare, and surgical repair has not been reported. We describe a successful, 1-stage correction in a 7-month-old boy with this condition, who had an additional complication of a single aortic outlet from the right ventricle and significant atrioventricular valve regurgitation...
October 11, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049532/pulmonary-valve-restitution-following-transannular-patch-repair-of-tetralogy-of-fallot
#4
Khushboo N Parikh, Nishant C Shah, Joseph B Clark, John L Myers
Chronic pulmonary insufficiency following transannular patch repair of tetralogy of Fallot may mandate restoration of a competent pulmonary valve. Pulmonary valve leaflets that are preserved at initial surgery may grow and develop normal morphology and subsequent valve repair may be possible. We reviewed our experience with native pulmonary valve restitution following transannular patch repair (2001-15). The cohort included 9 patients with a median age of 18.7 (range 10.6-31.3) years. Operative technique involved reapproximation of the anterior commissure of the pulmonary valve...
June 26, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29045596/the-relationship-between-cardiovascular-magnetic-resonance-imaging-measurement-of-extracellular-volume-fraction-and-clinical-outcomes-in-adults-with-repaired-tetralogy-of-fallot
#5
Kate Hanneman, Andrew M Crean, Bernd J Wintersperger, Paaladinesh Thavendiranathan, Elsie T Nguyen, Camilla Kayedpour, Rachel M Wald
Aims: Our aims were to explore cardiac magnetic resonance quantification of myocardial extracellular volume (ECV) in adults with repaired tetralogy of Fallot (rTOF) when compared with healthy controls and to investigate the association between ECV and major adverse cardiovascular outcomes. Methods and results: We prospectively recruited adults with rTOF (n = 44, 59% male, 32.9 ± 13.6 years) and evaluated right ventricular (RV) and left ventricular (LV) ECV by pre/post-gadolinium T1 measurements (modified Look-Locker inversion recovery technique) on a 1...
October 17, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29045289/genetic-origins-of-tetralogy-of-fallot
#6
Ari Morgenthau, William H Frishman
Due to improved survival and clinical outcomes, congenital heart disease is an area of growing importance within the medical community. As these patients reach adulthood and have children, there has been a growing appreciation for the increased risk of CHD among their offspring, strongly implying a genetic element. Given the growing wealth of genetic data available and these clinical implications, this review serves to re-examine the role of genetics within CHD, using Tetralogy of Fallot as a model pathology...
October 17, 2017: Cardiology in Review
https://www.readbyqxmd.com/read/29042165/sustained-ventricular-tachycardia-after-thoracic-traumatism-in-a-patient-with-repaired-tetralogy-of-fallot
#7
Isabel Molina Borao, Javier Urmeneta Ulloa, Naiara Calvo Galiano, Daniel Palanca Arias, Lorenzo Jiménez Montañés, Marta López Ramón
No abstract text is available yet for this article.
October 14, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29042164/pediatrics-spanish-registry-of-percutaneous-melody-pulmonary-valve-implantation-in-patients-younger-than-18-years
#8
Ruth Solana-Gracia, Fernando Rueda, Pedro Betrián, Federico Gutiérrez-Larraya, María Jesús Del Cerro, Manuel Pan, Juan Alcíbar, José Félix Coserría, José Manuel Velasco, José Luis Zunzunegui
INTRODUCTION AND OBJECTIVES: A decade has passed since the first Spanish percutaneous pulmonary Melody valve implant (PPVI) in March 2007. Our objective was to analyze its results in terms of valvular function and possible mid-term follow-up complications. METHODS: Spanish retrospective descriptive multicenter analysis of Melody PPVI in patients < 18 years from the first implant in March 2007 until January 1, 2016. RESULTS: Nine centers were recruited with a total of 81 PPVI in 77 pediatric patients, whose median age and weight were 13...
October 14, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29027295/progression-of-late-post-operative-atrial-fibrillation-in-patients-with-tetralogy-of-fallot
#9
Tanwier T T K Ramdjan, Elisabeth M J P Mouws, Christophe P Teuwen, Gustaf D S Sitorus, Charlotte A Houck, Ad J J C Bogers, Natasja M S de Groot
INTRODUCTION: ToF patients are at risk for ventricular deterioration at a relatively young age, which can be aggravated by AF development. Therefore, knowledge on AF development and its timespan of progression is essential to guide treatment strategies for AF. OBJECTIVE: We examined late post-operative AF onset and progression in ToF patients during long-term follow-up after ToF correction. In addition, co-existence of regular supraventricular tachyarrhythmias (SVT) and ventricular tachyarrhythmias (VTA) was analyzed...
October 13, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29025761/genome-wide-association-study-to-find-modifiers-for-tetralogy-of-fallot-in-the-22q11-2-deletion-syndrome-identifies-variants-in-the-gpr98-locus-on-5q14-3
#10
Tingwei Guo, Gabriela M Repetto, Donna M McDonald McGinn, Jonathan H Chung, Hiroko Nomaru, Christopher L Campbell, Anna Blonska, Anne S Bassett, Eva W C Chow, Elisabeth E Mlynarski, Ann Swillen, Joris Vermeesch, Koen Devriendt, Doron Gothelf, Miri Carmel, Elena Michaelovsky, Maude Schneider, Stephan Eliez, Stylianos E Antonarakis, Karlene Coleman, Aoy Tomita-Mitchell, Michael E Mitchell, M Cristina Digilio, Bruno Dallapiccola, Bruno Marino, Nicole Philip, Tiffany Busa, Leila Kushan-Wells, Carrie E Bearden, Małgorzata Piotrowicz, Wanda Hawuła, Amy E Roberts, Flora Tassone, Tony J Simon, Esther D A van Duin, Thérèse A van Amelsvoort, Wendy R Kates, Elaine Zackai, H Richard Johnston, David J Cutler, A J Agopian, Elizabeth Goldmuntz, Laura E Mitchell, Tao Wang, Beverly S Emanuel, Bernice E Morrow
BACKGROUND: The 22q11.2 deletion syndrome (22q11.2DS; DiGeorge syndrome/velocardiofacial syndrome) occurs in 1 of 4000 live births, and 60% to 70% of affected individuals have congenital heart disease, ranging from mild to severe. In our cohort of 1472 subjects with 22q11.2DS, a total of 62% (n=906) have congenital heart disease and 36% (n=326) of these have tetralogy of Fallot (TOF), comprising the largest subset of severe congenital heart disease in the cohort. METHODS AND RESULTS: To identify common genetic variants associated with TOF in individuals with 22q11...
October 2017: Circulation. Cardiovascular Genetics
https://www.readbyqxmd.com/read/29019299/additional-mechanism-for-left-ventricular-dysfunction-chronic-pulmonary-regurgitation-decreases-left-ventricular-preload-in-patients-with-tetralogy-of-fallot
#11
Pekka Ylitalo, Eero Jokinen, Kirsi Lauerma, Miia Holmström, Olli M Pitkänen-Argillander
BACKGROUND: Right ventricular dysfunction in patients with tetralogy of Fallot and significant pulmonary regurgitation may lead to systolic dysfunction of the left ventricle due to altered ventricular interaction. We were interested in determining whether chronic pulmonary regurgitation affects the preload of the left ventricle. In addition, we wanted to study whether severe chronic pulmonary regurgitation would alter the preload of the left ventricle when compared with patients having preserved pulmonary valve annulus...
October 11, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/29017776/early-outcomes-of-percutaneous-pulmonary-valve-implantation-using-the-edwards-sapien-xt-transcatheter-heart-valve-system
#12
Nikolaus A Haas, Ronald Giacomo Carere, Oliver Kretschmar, Eric Horlick, Josep Rodés-Cabau, Daniël de Wolf, Marc Gewillig, Michael Mullen, Anja Lehner, Cornelia Deutsch, Peter Bramlage, Peter Ewert
BACKGROUND: Patients with congenital or acquired heart defects affecting the pulmonary valve and right ventricular outflow tract (RVOT) commonly require multiple surgical interventions, resulting in significant morbidity. A less invasive alternative is percutaneous pulmonary valve implantation (PPVI). Though studies have previously reported the safety and efficacy of the early generation transcatheter heart valves (THVs), data on more recent devices are severely lacking. METHODS AND RESULTS: We performed a multinational, multicentre, retrospective, observational registry analysis of patients who underwent PPVI using the Edwards SAPIEN XT THV...
October 6, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29016767/dual-loop-circuit-of-ventricular-tachycardia-in-repaired-tetralogy-of-fallot-patient
#13
Masateru Takigawa, Ruairidh Martin, Takeshi Kitamura, Stefano Capellino Be, Pierre Jaïs, Frederic Sacher
No abstract text is available yet for this article.
August 8, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28993061/risk-comparison-for-prenatal-use-of-analgesics-and-selected-birth-defects-national-birth-defects-prevention-study-1997-2011
#14
Julia D Interrante, Elizabeth C Ailes, Jennifer N Lind, Marlene Anderka, Marcia L Feldkamp, Martha M Werler, Lockwood G Taylor, James Trinidad, Suzanne M Gilboa, Cheryl S Broussard
PURPOSE: To compare the use of nonsteroidal anti-inflammatory drugs (NSAIDs) and/or opioids to the use of acetaminophen without NSAIDs or opioids with respect to associations with birth defects. METHODS: We used data from the National Birth Defects Prevention Study (1997-2011). Exposure was self-reported maternal analgesic use from the month before through the third month of pregnancy (periconceptional). Adjusted odds ratios (aORs) were calculated to examine associations with 16 birth defects...
September 20, 2017: Annals of Epidemiology
https://www.readbyqxmd.com/read/28992910/extreme-tetralogy-of-fallot-with-polycythemia-in-a-ferret-mustela-putorius-furo
#15
Sara Dias, Marta Planellas, Albert Canturri, Jaume Martorell
A 5-month-old, intact male ferret (Mustela putorius furo) was presented with apathy, tachypnea and exercise intolerance. On initial physical examination, tachypnea and cyanosis were the two primary clinical signs detected. The complete blood count also revealed a severe polycythemia, with lymphopenia, neutrophilia and eosinophilia. Further diagnostic imaging tests were performed. The thoracic radiographs revealed cardiomegaly and a diffuse alveolar pulmonary pattern. Consequently, an echocardiography was performed and showed an interventricular septal defect, pulmonic artery occlusion, overriding of the aorta and right ventricle hypertrophy...
June 2017: Topics in Companion Animal Medicine
https://www.readbyqxmd.com/read/28991257/contribution-of-rare-inherited-and-de-novo-variants-in-2-871-congenital-heart-disease-probands
#16
Sheng Chih Jin, Jason Homsy, Samir Zaidi, Qiongshi Lu, Sarah Morton, Steven R DePalma, Xue Zeng, Hongjian Qi, Weni Chang, Michael C Sierant, Wei-Chien Hung, Shozeb Haider, Junhui Zhang, James Knight, Robert D Bjornson, Christopher Castaldi, Irina R Tikhonoa, Kaya Bilguvar, Shrikant M Mane, Stephan J Sanders, Seema Mital, Mark W Russell, J William Gaynor, John Deanfield, Alessandro Giardini, George A Porter, Deepak Srivastava, Cecelia W Lo, Yufeng Shen, W Scott Watkins, Mark Yandell, H Joseph Yost, Martin Tristani-Firouzi, Jane W Newburger, Amy E Roberts, Richard Kim, Hongyu Zhao, Jonathan R Kaltman, Elizabeth Goldmuntz, Wendy K Chung, Jonathan G Seidman, Bruce D Gelb, Christine E Seidman, Richard P Lifton, Martina Brueckner
Congenital heart disease (CHD) is the leading cause of mortality from birth defects. Here, exome sequencing of a single cohort of 2,871 CHD probands, including 2,645 parent-offspring trios, implicated rare inherited mutations in 1.8%, including a recessive founder mutation in GDF1 accounting for ∼5% of severe CHD in Ashkenazim, recessive genotypes in MYH6 accounting for ∼11% of Shone complex, and dominant FLT4 mutations accounting for 2.3% of Tetralogy of Fallot. De novo mutations (DNMs) accounted for 8% of cases, including ∼3% of isolated CHD patients and ∼28% with both neurodevelopmental and extra-cardiac congenital anomalies...
October 9, 2017: Nature Genetics
https://www.readbyqxmd.com/read/28988308/improving-the-role-of-echocardiography-in-studying-the-right-ventricle-of-repaired-tetralogy-of-fallot-patients-comparison-with-cardiac-magnetic-resonance
#17
Carolina D'Anna, Armando Caputi, Benedetta Natali, Benedetta Leonardi, Aurelio Secinaro, Gabriele Rinelli, Alessia Del Pasqua, Claudia Esposito, Adriano Carotti, Fabrizio Drago, Marcello Chinali
Right ventricular (RV) evaluation represents one of the major clinical tasks in the follow-up of repaired tetralogy of Fallot patients (rToF) with pulmonary valve regurgitation, as both severe RV dilatation and dysfunction are key factors in defining the need of pulmonary valve replacement. The aim of our study was to report the diagnostic accuracy of echocardiography in the identification of rToF patients with severely dilated and/or depressed RV as compared to cardiac magnetic resonance (CMR). Among our patients with rToF, a subgroup of 95 (17...
October 7, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28975024/quantification-of-pulmonary-regurgitation-in-patients-with-repaired-tetralogy-of-fallot-by-2d-phase-contrast-mri-differences-between-the-standard-method-of-velocity-averaging-and-a-pixel-wise-analysis
#18
Julio Sotelo, Pablo Bächler, Jesús Urbina, Gerard Crelier, Lida Toro, Myriam Ferreiro, Israel Valverde, Marcelo Andia, Cristian Tejos, Pablo Irarrazaval, Sergio Uribe
OBJECTIVES: To compare the values of pulmonary regurgitation in patients with repaired Tetralogy of Fallot quantified from two-dimensional phase-contrast data, by using a new pixel-wise analysis and the standard velocity-averaging method. DESIGN: Quantitative in silico and in vivo analysis. SETTING: Hospital Sótero del Río. The magnetic resonance images were acquired using a Philips Achieva 1.5T scanner. PARTICIPANTS: Twenty-five patients with repaired Tetralogy of Fallot who underwent cardiovascular magnetic resonance imaging requested by their referring physicians were included in this study...
January 2017: JRSM Cardiovascular Disease
https://www.readbyqxmd.com/read/28974283/is-mesocardia-with-left-sided-caval-vein-draining-to-coronary-sinus-a-contraindication-for-a-percutaneous-pulmonary-valve-implantation-a-case-description
#19
Marinos Kantzis, Christoph M Happel, Nikolaus A Haas
Introduction Although the right jugular vein approach for percutaneous pulmonary valve implantation is well described, there are no reports that describe a percutaneous pulmonary valve implantation through a left superior caval vein to coronary sinus pathway. Case A 14-year-old female with tetralogy of Fallot, mesocardia, left superior caval vein draining into the coronary sinus, and hemiazygos continuation of the inferior caval vein underwent ventricular septal defect closure, with homograft insertion from the right ventricle to the pulmonary artery, patch augmentation of the left pulmonary artery, and creation of an atrial communication...
October 4, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28970652/the-need-for-extracorporeal-membrane-oxygenation-in-adults-undergoing-congenital-heart-surgery-impact-and-trends-of-utilization
#20
Salvatore Aiello, Rohit S Loomba, Connor Kriz, Matthew Buelow, Saurabh Aggarwal, Rohit R Arora
INTRODUCTION: Adults with congenital heart disease (ACHD) represent a population with unique health-care needs. Many patients require cardiac surgery, with some requiring postoperative extracorporeal membrane oxygenation (ECMO). This study aimed to identify the risk factors for the need of postoperative ECMO and characterize the impact of ECMO on admission characteristics. METHODS: Data from the 2005-2012 iterations of the Nationwide Inpatient Sample were used. ACHD admissions over 18 years with a documented cardiac surgery were included...
September 2017: Indian Journal of Critical Care Medicine
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