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https://www.readbyqxmd.com/read/28813979/towards-low-back-support-with-a-passive-biomimetic-exo-spine
#1
Matthias B Naf, Laura De Rijcke, Carlos Rodriguez Guerrero, Matthew Millard, Bram Vanderborght, Dirk Lefeber
Low-Back Pain (LBP) affects a large portion of the working population. Preventive exoskeletons have been proposed to reduce the moments on the lower back, specifically around the lumbosacral (L5/S1) joint. High correlation has been shown, between reducing the moments around the L5/S1 joint and intervertebral compression forces, which in turn have been identified as a risk factor for developing LBP. However, most passive back support exoskeletons use rigid plates or stiff beams to support the spine that limit the range of motion of the wearer...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28805759/-diagnosis-and-treatment-of-dorsopathy-in-patients-with-connective-tissue-dysplasia
#2
M L Chukhlovina, A A Chukhlovin
AIM: To study the pathogenesis, clinical manifestations and treatment of dorsopathy in patients with connective tissue dysplasia. MATERIAL AND METHODS: Thirty-six patients, aged from 18 to 45 years, with lumbar-sacral radiculopathies associated with connective tissue dysplasia were examined. Detailed neurological examination, X-ray visualization and MRI of lumbosacral spine section, electromyographic assessment were performed. A five-point scale of neuro-vertebrological symptoms, the Numerical Rating Scale (NRS) and the Roland-Morris Low Back Pain and Disability Questionnaire were used...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28801520/evidence-that-central-pathways-that-mediate-defecation-utilize-ghrelin-receptors-but-do-not-require-endogenous-ghrelin
#3
Ruslan V Pustovit, Brid Callaghan, Mitchell T Ringuet, Nicole F Kerr, Billie Hunne, Ian M Smyth, Claudio Pietra, John B Furness
In laboratory animals and in human, centrally penetrant ghrelin receptor agonists, given systemically or orally, cause defecation. Animal studies show that the effect is due to activation of ghrelin receptors in the spinal lumbosacral defecation centers. However, it is not known whether there is a physiological role of ghrelin or the ghrelin receptor in the control of defecation. Using immunohistochemistry and immunoassay, we detected and measured ghrelin in the stomach, but were unable to detect ghrelin by either method in the lumbosacral spinal cord, or other regions of the CNS In rats in which the thoracic spinal cord was transected 5 weeks before, the effects of a ghrelin agonist on colorectal propulsion were significantly enhanced, but defecation caused by water avoidance stress (WAS) was reduced...
August 2017: Physiological Reports
https://www.readbyqxmd.com/read/28799104/accuracy-of-837-pedicle-screw-positions-in-degenerative-lumbar-spine-with-conventional-open-surgery-evaluated-by-computed-tomography
#4
Ilkka Saarenpää, Timo Laine, Jussi Hirvonen, Saija Hurme, Esa Kotilainen, Jaakko Rinne, Katariina Korhonen, Janek Frantzén
BACKGROUND: The spatial and directional accuracy of the positioning of pedicle screws in the lumbosacral spine with conventional open surgery assessed by computed tomography (CT) has been published in several studies, systematic reviews and meta-analyses with a short-term follow-up. Inaccurate pedicle screw insertion may cause neurologic symptoms and weakens the construct. METHODS: The data of 147 patients operated on with transpedicular screw fixation based on anatomical landmarks, supported by fluoroscopy, by a senior neurosurgeon in our clinic between 2000 and 2010 were analyzed retrospectively...
August 10, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28797833/percutaneous-rupture-of-zygapophyseal-joint-synovial-cysts-a-prospective-assessment-of-nonsurgical-management
#5
Gregory E Lutz, Michael R Nicoletti, George E Cyril, Julian R Harrison, Christopher Lutz, Jennifer L Solomon, Paul M Cooke, James F Wyss, Richard J Herzog, Peter J Moley
BACKGROUND: Although lumbar zygapophyseal joint synovial cysts are fairly well recognized, they are an uncommon cause of lumbosacral radicular pain. Non-operative treatments include percutaneous aspiration of the cysts under computed tomography or fluoroscopic guidance with a subsequent corticosteroid injection. However, there are mixed results in terms of long-term outcomes and cyst reoccurrence. This study prospectively evaluates percutaneous ruptures of zygapophyseal joint (Z-joint) synovial cysts for the treatment of lumbosacral radicular pain...
August 7, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28795477/exogenous-serotonin-regulates-colorectal-motility-via-the-5-ht2-and-5-ht3-receptors-in-the-spinal-cord-of-rats
#6
H Nakamori, K Naitou, Y Sano, H Shimaoka, T Shiina, Y Shimizu
BACKGROUND: We previously reported that intrathecal injection of noradrenaline or dopamine causes enhancement of colorectal motility. As these monoamines are neurotransmitters of descending pain inhibitory pathways in the spinal cord, we hypothesized that serotonin, which is one of the neurotransmitters involved in descending pain inhibition, also influences the lumbosacral defecation center. Therefore, we examined whether serotonin acting on the spinal defecation center enhances colorectal motility...
August 10, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28795472/does-ultrasound-guidance-add-accuracy-to-continuous-caudal-epidural-catheter-placements-in-neonates-and-infants
#7
Vrushali C Ponde, Vinit V Bedekar, Ankit P Desai, Kiran A Puranik
BACKGROUND: Caudo-lumbar and caudo-thoracic epidural anesthesia is an established technique that carries a low risk of dural puncture or spinal cord trauma in infants. Traditionally catheter advancement is based on external measurements. However, malpositioning of catheters are known to occur. We hypothesized that caudal-epidural catheters inserted under real-time ultrasound guidance may be more accurate than the accuracy of the measurements traditionally used for their placement. METHODS: We studied 25 patients, aged 2 days to 5 months, posted for abdominal or thoracic surgery, receiving general anesthesia followed by caudo-epidural continuous block...
August 10, 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/28776505/effects-of-cathodal-trans-spinal-direct-current-stimulation-on-lower-urinary-tract-function-in-normal-and-spinal-cord-injury-mice-with-overactive-bladder
#8
Zaghloul Ahmed
OBJECTIVE: Lower urinary tract (LUT) dysfunction is a monumental problem affecting quality of life following neurotrauma, such as spinal cord injury (SCI). Proper function of the bladder and its associated structures depends on coordinated activity of the neuronal circuitry in the spinal cord and brain. Disconnection between the spinal and brain centers controlling the LUT causes fundamental changes in the mechanisms involved in the micturition and storage reflexes. We investigated the effects of cathodal trans-spinal direct current stimulation (c-tsDCS) of the lumbosacral spine on bladder and external urinary sphincter (EUS) functions...
August 4, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28775057/localizing-the-l5-vertebra-using-nerve-morphology-on-mri-an-accurate-and-reliable-technique
#9
M E Peckham, T A Hutchins, S E Stilwill, M K Mills, B J Morrissey, E A R Joiner, R K Sanders, G J Stoddard, L M Shah
BACKGROUND AND PURPOSE: Multiple methods have been used to determine the lumbar vertebral level on MR imaging, particularly when full spine imaging is unavailable. Because postmortem studies show 95% accuracy of numbering the lumbar vertebral bodies by counting the lumbar nerve roots, attention to lumbar nerve morphology on axial MR imaging can provide numbering clues. We sought to determine whether the L5 vertebra could be accurately localized by using nerve morphology on MR imaging...
August 3, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28770402/kinematic-efficacy-of-supplemental-anterior-lumbar-interbody-fusion-at-lumbosacral-levels-in-thoracolumbosacral-deformity-correction-with-and-without-pedicle-subtraction-osteotomy-at-l3-an-in-vitro-cadaveric-study
#10
Benny T Dahl, Jonathan A Harris, Manasa Gudipally, Mark Moldavsky, Saif Khalil, Brandon S Bucklen
PURPOSE: Pedicle subtraction osteotomy (PSO) is performed to treat rigid, sagittal spinal deformities, but high rates of implant failure are reported. Anterior lumbar interbody fusion has been proposed to reduce this risk, but biomechanical investigation is lacking. The goal of this study was to quantify the (1) destabilizing effects of a lumbar osteotomy and (2) contribution of anterior lumbar interbody fusion (ALIF) at the lumbosacral junction as recommended in literature. METHODS: Fourteen fresh human thoracolumbosacral spines (T12-S1) were tested in flexion-extension (FE), lateral bending (LB), and axial rotation (AR)...
August 2, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28768846/clinical-phenotype-and-outcome-of-hepatitis-e-virus-associated-neuralgic-amyotrophy
#11
Jeroen J J van Eijk, Harry R Dalton, Paolo Ripellino, Richard G Madden, Catherine Jones, Miriam Fritz, Claudio Gobbi, Giorgia Melli, Emanuela Pasi, Jenny Herrod, Rebecca F Lissmann, Hamad H Ashraf, Mohamed Abdelrahim, Omar A B A L Masri, Montserrat Fraga, David Benninger, Thierry Kuntzer, Vincent Aubert, Roland Sahli, Darius Moradpour, Hélène Blasco-Perrin, Shahram Attarian, Rene Gérolami, Philippe Colson, Maria T Giordani, Johannes Hartl, Sven Pischke, Nan X Lin, Brendan N Mclean, Richard P Bendall, Marcus Panning, Jean-Marie Peron, Nassim Kamar, Jacques Izopet, Bart C Jacobs, Nens van Alfen, Baziel G M van Engelen
OBJECTIVE: To determine the clinical phenotype and outcome in hepatitis E virus-associated neuralgic amyotrophy (HEV-NA). METHODS: Cases of NA were identified in 11 centers from 7 European countries, with retrospective analysis of demographics, clinical/laboratory findings, and treatment and outcome. Cases of HEV-NA were compared with NA cases without evidence of HEV infection. RESULTS: Fifty-seven cases of HEV-NA and 61 NA cases without HEV were studied...
August 2, 2017: Neurology
https://www.readbyqxmd.com/read/28766519/-the-possibilities-for-diagnostics-of-prescription-of-death-coming-based-on-the-changes-in-the-lumbar-intervertebral-disks-the-comparison-of-the-morphological-immunohistochemical-and-topographical-findings
#12
V A Byval'tsev, I A Stepanov, A V Semenov, D V Perfil'ev, E G Belykh, L A Bardonova, S B Nikiforov, N P Sudakov, I V Bespyatykh, S L Antipina
The objective of the present study was the comprehensive analysis of the postmortem changes in the lumbar intervertebral disks within different periods after death. A total of seven vertebromotor segments were distinguished in the lumbosacral region of the vertebral column based on the examination of 7 corpses. All these segments were divided into three groups in accordance with the prescription of death coming as follows: up to 12 hours (group 1), between 12 and 24 hours (group 2), and between 24 and 36 hours (group 3) after death...
2017: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/28765790/a-minimally-invasive-surgical-technique-for-the-management-of-u-shape-sacral-fractures
#13
Randolph Gray, Robert Molnar, Mayuran Suthersan
INTRODUCTION: We present a small case series for the rare U-shape sacral fracture. The U-shape sacral fracture is characterised by bilateral longitudinal sacral fractures and a transverse sacral fracture through the S2 vertebral body. Historically it has been described following falls from a height and a high velocity mechanism is often required for this injury. We also describe a surgical technique for fixation of U-shape sacral fractures and subsequent implant removal 6 months post-operatively...
2017: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/28762430/determination-of-lumbosacral-transitional-vertebrae-in-kidney-urinary-bladder-x-ray-films-in-the-saudi-population
#14
Khalid G Khashoggi, Rawan M Hafiz, Yasmin M Bock, Abdullah M Kaki
To investigated the rate of occurrence of lumbosacral transitional vertebrae (LSTV), spinal variant, in kidney urinary bladder (KUB) plain radiographs in a Saudi population.  Methods: Between January 2012 to January 2015, KUB plain films obtained from patients at King Abdulaziz University Hospital, Jeddah, Saudi Arabia, were reviewed, and the presence or absence of LSTV was documented and classified as incomplete or complete. Patients who had evidence of spinal surgery that would obscure the view were excluded...
August 2017: Saudi Medical Journal
https://www.readbyqxmd.com/read/28761190/meningeal-dissemination-of-a-pituitary-carcinoma-to-the-cauda-equina-in-a-dog
#15
Nora K Sheehan, Helena Rylander, Neil Christensen, Laura A Nafe
An 8-year-old spayed female border collie dog was diagnosed with an invasive pituitary macrotumor. Five months after radiation therapy, the patient developed paraparesis and lumbosacral pain. Necropsy revealed a pituitary carcinoma with cauda equina drop metastasis. In cases of pituitary masses, meningeal dissemination should be considered if neurologic status declines.
August 2017: Canadian Veterinary Journal. la Revue Vétérinaire Canadienne
https://www.readbyqxmd.com/read/28758078/contrast-spread-in-the-superoposterior-approach-of-transforaminal-epidural-steroid-injections-for-lumbosacral-radiculopathy
#16
Young Cheol Jeong, Chung Ho Lee, Seok Kang, Joon Shik Yoon
OBJECTIVE: To observe the contrast spread in superoposterior transforaminal epidural steroid injection (SP TFESI) and investigate the correlation between spread patterns and efficacy. METHODS: Thirty-one patients with lumbosacral radiculopathy underwent single-level TFESI under fluoroscopy. The final needle tip position was targeted toward the SP quadrant of the intervertebral foramen. To observe the spread, 1 mL of contrast material was injected, followed by a steroid injection...
June 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28757906/lumbosacral-dorsal-rhizotomy-for-spastic-cerebral-palsy-a-health-technology-assessment
#17
(no author information available yet)
BACKGROUND: Cerebral palsy, a spectrum of neuromuscular conditions caused by abnormal brain development or early damage to the brain, is the most common cause of childhood physical disability. Lumbosacral dorsal rhizotomy is a neurosurgical procedure that permanently decreases spasticity and is always followed by physical therapy. The objectives of this health technology assessment were to evaluate the clinical effectiveness, safety, cost effectiveness, and family perspectives of dorsal rhizotomy...
2017: Ontario Health Technology Assessment Series
https://www.readbyqxmd.com/read/28756539/intraspinal-intradural-variations-of-nerve-roots
#18
Viktor Matejčík, Zora Haviarová, Andrej Šteňo, Roman Kuruc, Juraj Šteňo
PURPOSE: The aim of this work is to point out the intraspinal anatomical variations of nerve roots and their possible participation in radiculopathy. METHODS: The anatomical study was performed in 33 cadavers. There were 25 male cadavers aged 30-75 years and 8 female cadavers aged 45-77 years, with a mean age of 46.5 years to 24 h from death. All intradural rami communicantes between nerve roots were excised and examined histologically for the presence or absence of nervous tissue...
July 29, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28751140/lumbosacral-transitional-vertebra-possible-role-in-the-pathogenesis-of-adolescent-lumbar-disc-herniation
#19
Bangke Zhang, Liang Wang, Haibin Wang, Qunfeng Guo, Xuhua Lu, Deyu Chen
OBJECTIVE: To investigate the role of lumbosacral transitional vertebra (LSTV) in the pathogenesis of adolescent lumbar disc herniation (ALDH) and the association between LSTV type and the herniation level of ALDH. METHODS: This study was a retrospective case-control analysis of X-ray images. All adolescent patients who received surgical treatment for L4/5 or L5/S1 single level LDH in our department from 2010 to 2015 were eligible for the ALDH group. All adolescent patients admitted to our hospital during the same period who have ever underwent a plain anteroposterior radiological examination of the abdomen and meet the inclusion criteria that ensure the absence of any spinal disorders were selected into the control group...
July 24, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28746752/immunotherapy-for-diabetic-amyotrophy
#20
REVIEW
Yee Cheun Chan, Yew Long Lo, Edwin Sy Chan
BACKGROUND: People with diabetes mellitus (DM) sometimes present with acute or subacute, progressive, asymmetrical pain and weakness of the proximal lower limb muscles. The various names for the condition include diabetic amyotrophy, diabetic lumbosacral radiculoplexus neuropathies, diabetic femoral neuropathy or Bruns-Garland syndrome. Some studies suggest that diabetic amyotrophy may be an immune-mediated inflammatory microvasculitis causing ischaemic damage of the nerves. Immunotherapies would therefore be expected to be beneficial...
July 26, 2017: Cochrane Database of Systematic Reviews
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