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ovarian Teratoma dermoid

B Talvande, A Dorange, M Lecouflet, M Le Nezet, B Kianifard, H Maillard, M Duquenne
INTRODUCTION: Ovarian neuroendocrine tumors are extremely rare. In the ovary, the term of neuroendocrine tumor is usually related to carcinoid tumors although it may be sometimes applied to neuroendocrine carcinomas of non-small cells or small cells cancers usually occurring in the lungs. These carcinoid tumors may develop de novo or from other tumors including teratomas. CASE REPORT: We report a patient who presented with an ovarian carcinoid tumor developed, near or from a dermoid cyst, which was original by its mode of discovery in the dermatology department...
September 9, 2016: La Revue de Médecine Interne
Liang Cheng, Bingjian Lyu, Lawrence M Roth
Our knowledge of testicular germ cell neoplasms has progressed in the last few decades due to the description of germ cell neoplasia in situ (GCNIS) and a variety of specific forms of intratubular germ cell neoplasia, the discovery of isochromosome 12p and its importance in the development of invasiveness in germ cell tumors (GCTs), the identification of specific transcription factors for GCTs, and the recognition that a teratomatous component in mixed GCT represents terminal differentiation. Isochromosome 12p and 12p overrepresentation, collectively referred to as 12p amplification, are fundamental abnormalities that account for many types of malignant GCTs of the testis...
August 25, 2016: Human Pathology
Nicolas M Orsi, Mini Menon
Primary ovarian carcinoid tumors are exceptionally rare entities accounting for approximately 0.1% of all ovarian neoplasms. This report describes a primary ovarian neuroendocrine tumor arising in association with a mature cystic teratoma in a 65 year-old woman. Macroscopically, the unilateral adnexal tumor was composed of cystic, solid and mucinous elements which resolved into a dual component lesion histologically. The majority of the tumor displayed an organoid architecture with mild to moderate pleomorphism and no discernible mitotic activity, while approximately 10% consisted of sheets and groups of cells with highly pleomorphic nuclei, necrosis and occasional mitoses...
August 2016: Gynecologic Oncology Reports
Joana Sampaio, Inês Sarmento-Gonçalves, Joana Moreira Barros, Joana Felix, Pedro Tiago-Silva
Mature cystic teratomas, or dermoid tumors, are the most common benign ovarian neoplasms in young women. Malignant transformation is rare, and occurs in less than 2% of the cases. The heterogeneous histological composition of these tumors may be responsible for the occasional elevation of various tumor markers, such as Ca19-9 and Ca125. We describe one case of mature cystic teratoma in a 50-year old woman with the second highest level of Ca19-9 (8922.76 UI/mL) described in the literature. We concluded that abnormal levels of Ca19-9 are not necessarily associated with ovarian malignancy, and may lead to unnecessary medical intervention and patient anxiety...
July 2016: Revista Brasileira de Ginecologia e Obstetrícia
Riitta Koivisto-Korander, Ralf Bützow
Mature germ cell derived cystic teratoma of the ovary, i.e. dermoid cyst, is a common ovarian neoplasm, seldom progressing to malignancy. Malignized dermoid cyst is most commonly diagnosed in a woman of approx. 50 years of age, either during or after an operation. Owing to the rarity of the disease, the lines of treatment are based on retrospective series of cases.
2016: Duodecim; Lääketieteellinen Aikakauskirja
Lorna A Brudie, Faizan Khan, Michael J Radi, Melissa M Yates, Sarfraz Ahmad
Mature cystic teratomas constitute 10-20% of all ovarian neoplasms. Malignant transformation is very rare occurring in only 0.1-2% of mature teratoma cases. Malignant melanoma is among the least common transformations. Herein, we describe a case of young woman initially undergoing evaluation for infertility who was found to have malignant melanoma arising in a mature dermoid cyst. She subsequently underwent unilateral salpingo-oophorectomy with staging procedure with benign pathology. There was no need for adjuvant therapy and the patient is without disease to date (nearly 10-months in follow-up now)...
April 2016: Gynecologic Oncology Reports
Abha Sinha, Ayman A A Ewies
Although ovarian mature cystic teratomas are the commonest adnexal masses occurring in premenopausal women, there are many challenges faced by gynecologists on deciding upon the best surgical management. There is uncertainty, lack of consensus, and variation in surgical practices. This paper critically analyzes various surgical approaches and techniques used to treat these cysts in an attempt to outline a unified guidance. MEDLINE and EMBASE databases were searched in January 2015 with no date limit using the key words "ovarian teratoma" and "ovarian dermoid...
2016: Obstetrics and Gynecology International
F Bonilla-Musoles, C Cadete, F Raga, F Bonilla, N G Osborne, O Caballero
OBJECTIVE: To demonstrate that the use of 3D/4D HDLive increases the image quality in the diagnosis of benign cystic ovarian teratomas. MATERIALS AND METHODS: 3D/HDLive ultrasound (US) was used in 31 cases of suspected ovarian cystic teratoma using vaginal 2D US. The following pathognomonic images of mature cystic teratomas were considered for diagnosis: 1) a cystic, unilocular lesion with a densely echogenic tubercle (Rokitansky nodule); 2) a diffuse or partially echogenic mass usually demonstrating sound attenuation; 3) fluid-fluid/fat-fluid levels; 4) dermoid mesh with hyperechogenic calcifications indicating the presence of bone, teeth, or other ectodermally-derived structure; 5) multiple mobile spherical structures (fat globules)...
2016: Clinical and Experimental Obstetrics & Gynecology
Ancuta Augustina Gheorghisan-Galateanu, Mara Carsote, Anda Dumitrascu, Andreea Geleriu, Dana Terzea, Catalina Poiana
Ovarian teratoma has various presentations. We present a 28-year female diagnosed with a tumour after a fainting episode. Medical history was non-contributory except for mild intermittent pelvic pain. Cardiologic and neurological evaluation found no cause of syncope. Abdominal ultrasound revealed a right ovarian tumour that was laparoscopically removed. The menses continued to be normal. The pathological exam showed an encapsulated tumour of 8 cm with hair and small bone parts (mature teratoma with a cystadenoma)...
March 2016: JPMA. the Journal of the Pakistan Medical Association
P Pradhan, M Thapa
Dermoid cysts or mature cystic teratoma are the most common type of ovarian germ cell tumor usually occurring in the reproductive age group. They are commonly unilateral and 10-12 % can be bilateral. They are commonly multicystic and contain sebaceous fluid as well as tissue of three germ cell layers e.g. ectoderm (skin, hair, brain) mesoderm (muscle, fat ,teeth ,bone, and cartilage) and endoderm (mucious and ciliated epithelium).These teratomas usually arise from the gonads but has been found anywhere in the body...
April 2014: JNMA; Journal of the Nepal Medical Association
Yuki Tazo, Yoshihiro Yoshimura, Takashi Shoda, Noriyuki Kyushima, Takemichi Okada, Hitoshi Yamazaki
BACKGROUND: Ovarian mature cystic teratoma (MCT) is a common neoplasm in women. While malignant transformation of MCT is relatively rare, squamous cell carcinoma is the most frequent malignant neoplasm arising from MCT. Some tumor markers have been reported to be useful for prediction of MCT malignant transformation prior to operation. However, widely accepted use of these markers remains to be established. In the present study, we report the usefulness of frozen section assessment during operation, as well as preoperative measurement of tumor marker levels...
2016: Journal of Medical Case Reports
Seung-Hyuk Shim, Sun Joo Lee, Soo-Nyung Kim, Su Hyun Chae, Ji Young Lee
OBJECTIVE: To compare transvaginal versus conventional laparoscopy for dermoid cysts. STUDY DESIGN: We retrospectively analyzed all con-secutive patients with dermoid cysts who underwent transvaginal (n = 219) or conventional (n = 245) laparoscopy from 2007-2013 at our institution. Each group of patients was matched (1:1 ratio) for age, body mass index, previous surgical history, cyst diameter, bilaterality, and cystectomy/oophorectomy. Surgical outcomes were compared between the 2 groups...
November 2015: Journal of Reproductive Medicine
J M Rhymes, T Gorman, R A Sasso
UNLABELLED: Intratubal teratoma is a very rare condition. The authors believe to present the first case of a completely intratubal mature cystic teratoma with a contralateral intraovarian teratoma. Preoperative ultrasound examination allowed the intraoperative diagnosis of this rare condition, hence allowing appropriate surgical management. MATERIALS AND METHODS: A 19-year-old woman presented with a history of pelvic pain and severe dysmenorrhea. Ultrasound examination initially suggested bilateral ovarian dermoids...
2015: Clinical and Experimental Obstetrics & Gynecology
N S Chitrakar, S Suwal, S Neupane
Parasitic ovarian dermoid cysts are very rare. We report a rare case of bilateral ovarian dermoid cysts with parasitic teratoma at the hepato renal space measuring 11x11x6 cm while the other was twisted measuring 10x6x5 cm.Right ovary and tube were absent. The mass found at the hepato renal space was surrounded by and adherent to the omentum with viable tubal fimbria like structure at upper surface. Histopathologically both masses were confirmed as mature ovarian teratoma. The etiology of parasitic teratoma would be due to torsion followed by autoamputation and reimplantation of the right ovarian dermoid cyst...
May 2015: Journal of Nepal Health Research Council
An-Jen Chiang, Di-Rong Chen, Jiin-Tsuey Cheng, Tsung-Hsien Chang
OBJECTIVE: Primary squamous cell carcinoma (SCC) of the ovary in humans is rare. Most cases represent a malignant transformation of ovarian teratoma, Brenner tumor, or endometriosis. The etiology of this cancer remains largely unknown. Human papillomavirus (HPV) infection is a critical factor that induces tumor formation, particularly cervical cancer. Therefore, this study aimed to evaluate the association of HPV with malignant transformation of mature cystic teratoma (MCT) into SCC of the ovary...
October 2015: Taiwanese Journal of Obstetrics & Gynecology
G Jalencas, E González Bosquet, L Guirado, M Fernandez Arias, B Ruiz de Gauna, L Fiores, M D Gómez Roig, J Callejo
PURPOSE OF INVESTIGATION: To describe the surgical management and diagnoses of mature ovarian teratomas and ovarian strumas in the present centre. MATERIALS AND METHODS: Descriptive retrospective analysis of cases of mature ovarian teratoma at the present university-associated hospital over ten years. RESULTS: The mean age was 29 years and in 17 patients the diagnosis was made during other surgery. When surgery was planned, the approach was 80...
2015: Clinical and Experimental Obstetrics & Gynecology
Jamie Stanhiser, Haider Mahdi, Gabriela Rosa, Holly Harper, Dale Shepard, Peter G Rose, Andres A Roma
We report our experience with prostatic-type tissue in ovarian teratomas, and in particular we highlight a case of prostatic-type adenocarcinoma arising within a mature cystic ovarian teratoma in a 32-yr-old woman. On gross examination, the cyst consisted of typical features of a dermoid cyst. Closer examination revealed a single 1.5-cm solid nodule within the cyst. Microscopically, it was composed of a small cyst-like structure lined by urothelium and to one side glandular and stromal tissue consistent with prostate parenchyma...
March 2016: International Journal of Gynecological Pathology
Jasmine Multani, Sari Kives
PURPOSE OF REVIEW: Dermoid ovarian cysts, or mature cystic teratomas, are the most common benign ovarian neoplasms found in adolescents and they continue to challenge clinicians about correct management and treatment. RECENT FINDINGS: Laparoscopic treatment for large cysts is usually the preferred method with ovarian preservation. Cyst rupture and recurrence still remain potential risks of this surgical approach. Torsion can occur frequently in the population and when it occurs, fertility-sparing treatment should be attempted...
October 2015: Current Opinion in Obstetrics & Gynecology
Mamoru Kakuda, Shinya Matsuzaki, Eiji Kobayashi, Kiyoshi Yoshino, Eiichi Morii, Tadashi Kimura
Mature cystic teratoma is a germ cell tumor of the ovaries and is often observed in clinical practice. However, extragonadal teratomas are rare tumors and have been reported outside the ovaries, (e.g., in the greater omentum). The mechanism underlying the development of extragonadal teratomas remains unknown. We encountered a case of extragonadal teratoma in the pouch of Douglas that appeared to be a parasitic dermoid cyst. From our experience and the literature review, we discuss the potential mechanism leading to the development of extragonadal teratomas...
November 2015: Journal of Minimally Invasive Gynecology
A Wincewicz, P Lewitowicz, O Adamczyk-Gruszka, S Sulkowski, L Kanczuga-Koda, M Koda
Combined ovarian tumors are found in common pathologic practice due to amazing potential of ovarian tissue to copy almost every tissue of human body and imitate many neoplasms of various other organs in a very flexible way. A multicystic tumor is presented in this case report of 35-year-old woman. It consisted of a cyst with sebum and hair and cavities with papillomatous projections and mucus. The ovarian tumor was diagnosed a mature cystic teratoma presenting mainly as dermoid cyst and mucinous adenocarcinoma in situ, arising within atypical proliferative mucinous tumor...
2015: European Journal of Gynaecological Oncology
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