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https://www.readbyqxmd.com/read/28647602/improvement-of-lindane-removal-by-streptomyces-sp-m7-by-using-stable-microemulsions
#1
Juliana Maria Saez, Verena Casillas García, Claudia Susana Benimeli
Lindane is an organochlorine pesticide which persists in the environment and can cause serious health problems due to its chlorinated and hydrophobic nature. Microemulsions are isotropic and macroscopically homogeneous systems with high solubilization capacity of hydrophilic and hydrophobic compounds. The aim of this study was to evaluate the removal of high concentrations of lindane by the actinobacterium Streptomyces sp. M7 in aqueous and soil systems in the presence of stable microemulsions. Three stable microemulsions were successfully formed with Tween 80, 1-pentanol and three vegetable oils...
June 22, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28645771/dectin-1-expression-by-macrophages-and-related-antifungal-mechanisms-in-a-murine-model-of-sporothrix-schenckii-sensu-stricto-systemic-infection
#2
Juliana Aparecida Jellmayer, Lucas Souza Ferreira, Francine Alessandra Manente, Amanda Costa Gonçalves, Marisa Campos Polesi, Alexander Batista-Duharte, Iracilda Zeppone Carlos
The available information about the role of Dectin-1 in sporotrichosis is scarce. Hence, we aimed to assess Dectin-1 expression by macrophages and the activation of some related antifungal mechanisms during the Sporothrix schenckii sensu stricto infection as a first attempt to elucidate the role of this receptor in sporotrichosis. Balb/c mice were intraperitoneally infected with S. schenckii sensu stricto yeast ATCC 16345 and euthanized on days 5, 10 and 15 post-infection, when the following parameters were evaluated: fungal burden in spleen, Dectin-1 expression and nitric oxide (NO) production by peritoneal macrophages, as well as IL-1β, TNF-α and IL-10 ex vivo secretion by these same cells...
June 20, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28645649/evaluation-of-a-selective-chromogenic-medium-for-detecting-vancomycin-resistant-enterococci
#3
Renata Oliveira Soares, Adriana Medianeira Rossato, Gustavo Enck Sambrano, Neidimar Cezar Corrêa Tolfo, Juliana Caierão, Thiago Galvão da Silva Paim, Pedro Alves d'Azevedo
Rapid identification of vancomycin-resistant enterococci (VRE) can assist in choosing the appropriate treatment and preventing VRE spread. The performance of chromID™ VRE agar was evaluated using 184 clinical isolates of Enterococcus spp. and reference strains. The test had a sensitivity of 95.52% but a low specificity of 30%.
June 8, 2017: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/28644858/the-flame-retardant-de-71-a-mixture-of-polybrominated-diphenyl-ethers-inhibits-human-differentiated-thyroid-cell-function-in-vitro
#4
Thit Mynster Kronborg, Juliana Frohnert Hansen, Åse Krogh Rasmussen, Katrin Vorkamp, Claus Henrik Nielsen, Marie Frederiksen, Jacob Hofman-Bang, Christoffer Holst Hahn, Louise Ramhøj, Ulla Feldt-Rasmussen
BACKGROUND: Normal thyroid function is essential for general growth and metabolism, but can be affected by endocrine disrupting chemicals (EDCs). Polybrominated diphenyl ethers (PBDEs) have been used worldwide to reduce flammability in different materials and are suspected to be EDCs. The production of the commercial Penta- and OctaBDE mixtures is banned, but DecaBDEs and existing products may leak PBDEs into the environment. Our aim was to investigate the effect of the PentaBDE mixture DE-71 on human thyroid cells in vitro...
2017: PloS One
https://www.readbyqxmd.com/read/28642658/study-of-the-anterolateral-ligament-of-the-knee-in-formalin-embedded-cadavers
#5
Paloma Batista Almeida Fardin, Juliana Hott de Fúcio Lizardo, Josemberg da Silva Baptista
OBJECTIVE: To verify the incidence and characterize morphologically the anterolateral ligament of the knee (ALL) in cadaveric samples of the collection of the Laboratory of Anatomy of the Department of Morphology of the Universidade Federal do Espírito Santo. METHODS: Dissections and cross sections were performed for mesoscopic analysis of the anterolateral region of 15 knees preserved in 4% formalin solution in order to identify the ALL. RESULTS: After dissection of the skin and subcutaneous tissue of the knee anterolateral region, it was possible to identify the iliotibial tract (ITT), the patellar ligament and the femoral biceps tendon...
March 2017: Acta Ortopedica Brasileira
https://www.readbyqxmd.com/read/28641588/health-technology-performance-assessment-real-world-evidence-for-public-healthcare-sustainability
#6
Augusto Afonso Guerra-Júnior, Lívia Lovato Pires de Lemos, Brian Godman, Marion Bennie, Cláudia Garcia Serpa Osorio-de-Castro, Juliana Alvares, Aine Heaney, Carlos Alberto Vassallo, Björn Wettermark, Gaizka Benguria-Arrate, Iñaki Gutierrez-Ibarluzea, Vania Cristina Canuto Santos, Clarice Alegre Petramale, Fransciso de Assis Acurcio
OBJECTIVES: Health technology financing is often based on randomized controlled trials (RCTs), which are often the same ones used for licensing. Because they are designed to show the best possible results, typically Phase III studies are conducted under ideal and highly controlled conditions. Consequently, it is not surprising that technologies do not always perform in real life in the same way as controlled conditions. Because financing (and price paid) decisions can be made with overestimated results, health authorities need to ask whether health systems achieve the results they expect when they choose to pay for a technology...
June 23, 2017: International Journal of Technology Assessment in Health Care
https://www.readbyqxmd.com/read/28637884/vaccination-establishes-clonal-relatives-of-germinal-center-t-cells-in-the-blood-of-humans
#7
Antje Heit, Frank Schmitz, Sarah Gerdts, Britta Flach, Miranda S Moore, Jonathan A Perkins, Harlan S Robins, Alan Aderem, Paul Spearman, Georgia D Tomaras, Stephen C De Rosa, M Juliana McElrath
Germinal center T follicular helper cells (GCTfh) in lymphatic tissue are critical for B cell differentiation and protective antibody induction, but whether GCTfh establish clonal derivatives as circulating memory T cells is less understood. Here, we used markers expressed on GCTfh, CXCR5, PD1, and ICOS, to identify potential circulating CXCR5(+)CD4(+) Tfh-like cells (cTfh) in humans, and investigated their functional phenotypes, diversity, and ontogeny in paired donor blood and tonsils, and in blood after vaccination...
June 21, 2017: Journal of Experimental Medicine
https://www.readbyqxmd.com/read/28637094/acclimation-responses-to-high-light-by-guazuma-ulmifolia-lam-malvaceae-leaves-at-different-stages-of-development
#8
Anderson Kikuchi Calzavara, Juliana Silva Rocha, Geovana Lourenço, Karina Sanada, Cristiano Medri, Edmilson Bianchini, José Antonio Pimenta, Renata Stolf-Moreira, Halley Caixeta Oliveira
The recomposition of deforested environments requires the prior acclimation of seedlings to full sun in nurseries. Seedlings can overcome excessive light either through the acclimation of pre-existing fully expanded leaves or through the development of new leaves that are acclimated to the new light environment. Here, we compared the acclimation capacity of mature (MatL, fully expanded at the time of transfer) and newly expanded leaves (NewL, expanded after the light shift) of Guazuma ulmifolia Lam. (Malvaceae) seedlings to high light...
June 21, 2017: Plant Biology
https://www.readbyqxmd.com/read/28637033/quantitative-swept-source-optical-coherence-tomography-of-early-enamel-erosion-in-vivo
#9
Rupert S Austin, Maisalamah Haji Taha, Frederic Festy, Richard Cook, Manoharan Andiappan, Juliana Gomez, Iain A Pretty, Rebecca Moazzez
Swept-source optical coherence tomography (SS-OCT) shows potential for the in vivo quantitative evaluation of micro-structural enamel surface phenomena occurring during early erosive demineralization. This randomized controlled single-blind cross-over clinical study aimed to evaluate the use of SS-OCT for detecting optical changes in the enamel of 30 healthy volunteers subjected to orange juice rinsing (erosive challenge) in comparison to mineral water rinsing (control), according to wiped and non-wiped enamel surface states...
June 22, 2017: Caries Research
https://www.readbyqxmd.com/read/28635163/early-pregnancy-body-mass-index-modifies-the-association-of-pre-pregnancy-dietary-patterns-with-serum-polyunsaturated-fatty-acid-concentrations-throughout-pregnancy-in-brazilian-women
#10
Camila Benaim, Ana Amélia Freitas-Vilela, Thatiana de Jesus Pereira Pinto, Jaqueline Lepsch, Dayana Rodrigues Farias, Juliana Dos Santos Vaz, Tatiana El-Bacha, Gilberto Kac
Dietary patterns (DPs) have been described as an important factor that may influence polyunsaturated fatty acid (PUFA) concentrations and body mass index (BMI) during pregnancy. We aim to evaluate the association between pre-pregnancy DPs and serum PUFA percentages throughout pregnancy considering early pregnancy BMI as a possible effect modifier. A prospective cohort of 154 pregnant women was followed (5th-13th, 20th-26th, and 30th-36th gestational weeks). Serum PUFA concentrations (total n-3 and total n-6, eicosapentaenoic + docosahexaenoic acids) were measured in each trimester and expressed as percentages...
June 21, 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/28631899/dual-molecular-diagnosis-contributes-to-atypical-prader-willi-phenotype-in-monozygotic-twins
#11
Fernanda S Jehee, Valdirene T de Oliveira, Juliana Gurgel-Giannetti, Rafaella X Pietra, Fernando V M Rubatino, Natália V Carobin, Gabrielle S Vianna, Mariana L de Freitas, Karla S Fernandes, Beatriz S V Ribeiro, Hennie T Brüggenwirth, Roza Ali-Amin, Janson J White, Zeynep C Akdemir, Shalini N Jhangiani, Richard A Gibbs, James R Lupski, Monica C Varela, Célia Koiffmann, Carla Rosenberg, Cláudia M B Carvalho
We describe monozygotic twin girls with genetic variation at two separate loci resulting in a blended phenotype of Prader-Willi syndrome and Pitt-Hopkins syndrome. These girls were diagnosed in early infancy with Prader-Willi syndrome, but developed an atypical phenotype, with apparent intellectual deficiency and lack of obesity. Array-comparative genomic hybridization confirmed a de novo paternal deletion of the 15q11.2q13 region and exome sequencing identified a second mutational event in both girls, which was a novel variant c...
June 20, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28629730/synergistic-antinociceptive-effect-of-a-calcium-channel-blocker-and-a-trpv1-blocker-in-an-acute-pain-model-in-mice
#12
Manuella R Palhares, Juliana F Silva, Marcio Junior S Rezende, Duana C Santos, Cláudio A Silva-Junior, Márcia H Borges, Juliano Ferreira, Marcus V Gomez, Célio J Castro Junior
AIMS: Extensive evidence supports a role for voltage-gated calcium channels (VGCC) and TRPV1 receptors in pain transmission and modulation. We investigated the profile of analgesic interaction between Phα1β toxin (a VGCC blocker) and SB366791 (selective TRPV1 antagonist) in a model of acute pain induced by capsaicin. Changes in body temperature induced by combination regimens were also evaluated. MAIN METHODS: Isobolographic approach with a fixed dose-ratio of combined drugs was used to determine whether antinociceptive interaction of Phα1β and SB366791 are subadditive, additive or synergic...
June 16, 2017: Life Sciences
https://www.readbyqxmd.com/read/28629167/igg-avidity-test-in-congenital-toxoplasmosis-diagnoses-in-newborns
#13
Zulmirene Cardoso Fonseca, Isolina Maria Xavier Rodrigues, Natália Cruz E Melo, Juliana Boaventura Avelar, Ana Maria Castro, Mariza Martins Avelino
The goal of this study was to investigate the importance of IgG avidity testing in newborns (NBs) diagnosed with early congenital toxoplasmosis. We collected samples from 88 puerperae infected by Toxoplasma gondii (T. gondii) and their NBs (48 acutely-infected puerperae (AIP) and 40 chronically-infected puerperae (CIP)), from two public maternity hospitals in Goiania city, Goias, Brazil, from 2010 to 2015. Specific anti-T. gondii IgM and IgG serum levels and IgG avidity tests were evaluated using chemiluminescence...
June 18, 2017: Pathogens
https://www.readbyqxmd.com/read/28627917/functional-intimacy-needing-but-not-wanting-the-touch-of-a-stranger
#14
Juliana Schroeder, Ayelet Fishbach, Chelsea Schein, Kurt Gray
Intimacy is often motivated by love, but sometimes it is merely functional. For example, disrobing and being touched at an airport security check serves the goal of catching a flight, not building a relationship. We propose that this functional intimacy induces discomfort, making people prefer greater social distance from their interaction partner. Supporting this prediction, participants who considered (Experiments 1 and 2) or experienced (Experiment 3) more physically intimate medical procedures preferred a health provider who is less social...
June 19, 2017: Journal of Personality and Social Psychology
https://www.readbyqxmd.com/read/28627218/performance-evaluation-of-three-platforms-with-ultrasensitive-ligand-binding-assay-potential
#15
Kyra Juliana Cowan, Albert Geiger, Hans Hornauer, Robyn Rourick, Patricia Yanira Siguenza
AIM: We evaluated three immunoassay-based technologies and their biomarker kits, by determining precision, parallelism and detectability of analytes of interest. MATERIALS & METHODS: We compared ultrasensitive assays for three biomarkers: interleukins IL-6, IL-13 and IL-17A using kits obtained from Roche (IMPACT platform - proprietary platform), Singulex (Erenna(®)) and Quanterix (Simoa(™)). We defined the true LLOD as the LLOQs, and provided disease-specific parallelism results and detectability levels for endogenous analyte, which were good across platforms, though they varied from analyte to analyte...
June 19, 2017: Bioanalysis
https://www.readbyqxmd.com/read/28627188/effect-of-glutamine-on-liver-injuries-induced-by-intestinal-ischemia-reperfusion-in-rats
#16
Renata Hartmann, Francielli Licks, Elizângela Gonçalves Schemitt, Josieli Raskopf Colares, Juliana Da Silva, Rosa Maria Moura, Gilmara Pandolfo Zabot, Henrique Sarubbi Fillmann, Norma Possa Marroni
INTRODUCTION: Intestinal ischemia-reperfusion (I/R) injury may cause cell and tissue damage, reaching also other organs such as the liver. Because of the involvement of free radicals in I/R injury, treatment options with antioxidants have been studied and tested. OBJECTIVE: To evaluate the effect of glutamine (Gln) in the liver of animals with intestinal I/R injury. METHODS: We used 20 male Wistar rats divided into four groups: sham-operated (SO); glutamine + sham-operated (G+SO); intestinal ischemia-reperfusion (I/R); glutamine + intestinal ischemia-reperfusion (G+I/R)...
June 5, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28626963/exercise-training-modulates-the-hepatic-renin-angiotensin-system-in-fructose-fed-rats
#17
Eliete Dalla Corte Frantz, Renata Frauches Medeiros, Isabele Gomes Giori, Juliana Bittencourt Silveira Lima, Thais Bento-Bernardes, Thaiane Gadioli Gaique, Caroline Fernandes-Santos, Tiago Fernandes, Edilamar Menezes Oliveira, Carla Paulo Vieira, Carlos Adam Conte-Junior, Karen Jesus Oliveira, Antonio Claudio Lucas da Nóbrega
The renin-angiotensin system (RAS) has been implicated in the development of metabolic syndrome. We investigated whether the hepatic RAS is modulated by exercise training and if this modulation improves the deleterious effects of fructose overload in rats. Male Wistar rats were divided into (n = 8 each) control (CT), exercise control (CT-Ex), high fructose (HFr) and exercise high fructose (HFr-Ex) groups. Fructose-drinking rats received D-fructose (100 g L(-1) ). After two weeks, CT-Ex and HFr-Ex rats were assigned to a treadmill training protocol at moderate-intensity for eight weeks (60 min day(-1) , four days/week)...
June 19, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28625636/prognostic-impact-of-ttf-1-expression-in-patients-with-stage-iv-lung-adenocarcinomas
#18
Juliana B Schilsky, Ai Ni, Linda Ahn, Sutirtha Datta, William D Travis, Mark G Kris, Jamie E Chaft, Natasha Rekhtman, Matthew D Hellmann
OBJECTIVES: Thyroid transcription factor 1 (TTF-1) is routinely tested in the diagnostic evaluation of suspected lung cancers, is commonly expressed by lung adenocarcinomas, and may modulate lung cancer biology. We examined the role of TTF-1 as a predictive and prognostic marker in patients with advanced lung adenocarcinomas. MATERIALS AND METHODS: We analyzed clinical, pathologic, and molecular features, treatments received, and overall survival obtained from the medical records of 479 consecutive patients at a single site with stage IV lung adenocarcinomas and evaluable TTF-1 expression...
June 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/28625001/nanostructured-sba-15-host-applied-in-ketorolac-tromethamine-release-system
#19
Jorgelina Cussa, Juliana M Juárez, Marcos B Gómez Costa, Oscar A Anunziata
The ordered mesoporous silica SBA-15 has been applied in studies of ketorolac tromethamine adsorption and release. The SBA-15 materials with hexagonal and regular structure were obtained using a triblock copolymer Pluronic P123 as a template and TEOS as a silica source. Ketorolac tromethamine was adsorbed into SBA-15 silica nanochannels using ethanol as solvent. The physicochemical and textural properties of SBA-15 and ketorolac tromethamine/SBA-15 were characterized by X-ray diffraction, thermogravimetric analysis, transmission electron microscopy, fourier transform infrared spectroscopy and BET surface studies...
August 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28624873/short-communication-first-report-of-nematodes-parasitizing-the-four-eyed-fish-anableps-anableps-pisces-cyprinodontiformes
#20
Juliana Souza Ribeiro, Francisco Carlos Rodrigues de Oliveira, Nicole Brand Ederli
The genus Anableps is composed of species Anableps anableps, Anableps dowi, and Anableps microlepis. These fishes are tropical and usually live on the surface of brackish water, being popularly known as four-eyed-fishes due to the presence of prominent eyes and a pupil split horizontally. A. anableps and A. microlepis are considered as sister species that live in sympatry in South America. A. dowi, however, is restricted to the Pacific Ocean (Central America) and is considered the most primitive species of this genus...
June 17, 2017: Parasitology Research
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