keyword
MENU ▼
Read by QxMD icon Read
search

Juliana

keyword
https://www.readbyqxmd.com/read/28548878/immunophenotyping-of-the-cerebrospinal-fluid-as-a-prognostic-factor-at-diagnosis-of-acute-lymphoblastic-leukemia-in-children-and-adolescents
#1
Camila Silva Peres Cancela, Mitiko Murao, Juliana Godoy Assumpção, Marcelo Eduardo de Lima Souza, Antonio Vaz de Macedo, Marcos Borato Viana, Benigna Maria De Oliveira
This study aimed at evaluating the use of immunophenotyping (IMP) in the identification of blast cells in the cerebrospinal fluid (CSF) of children and adolescents with acute lymphoblastic leukemia (ALL). Sixty-seven patients aged 18 years or younger were included. Fifty-five CSF samples were analyzed at initial diagnosis and 17 at the time of relapse. A cytological analysis (CA) was performed in all 72 samples, while IMP was done in 63. Blasts were identified in only three samples by CA, whereas all three samples were found negative by IMP, one of which had no isolation of nucleated cells after centrifugation...
May 26, 2017: Pediatric Hematology and Oncology
https://www.readbyqxmd.com/read/28548004/reduced-cellularity-of-bone-marrow-in-multiple-sclerosis-with-decreased-msc-expansion-potential-and-premature-ageing-in-vitro
#2
Juliana Redondo, Pamela Sarkar, Kevin Kemp, Paul F Virgo, Joya Pawade, Aimie Norton, David C Emery, Martin G Guttridge, David I Marks, Alastair Wilkins, Neil J Scolding, Claire M Rice
BACKGROUND: Autologous bone-marrow-derived cells are currently employed in clinical studies of cell-based therapy in multiple sclerosis (MS) although the bone marrow microenvironment and marrow-derived cells isolated from patients with MS have not been extensively characterised. OBJECTIVES: To examine the bone marrow microenvironment and assess the proliferative potential of multipotent mesenchymal stromal cells (MSCs) in progressive MS. METHODS: Comparative phenotypic analysis of bone marrow and marrow-derived MSCs isolated from patients with progressive MS and control subjects was undertaken...
May 1, 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/28547936/fragment-based-drug-discovery-as-alternative-strategy-to-the-drug-development-for-neglected-diseases
#3
REVIEW
Juliana da Fonseca Rezende E Mello, Renan Augusto Gomes, Drielli Gomes Vital-Fujii, Glaucio Monteiro Ferreira, Gustavo Henrique Goulart Trossini
Neglected diseases (NDs) affect large populations and almost whole continents, representing 12% of the global health burden. In contrast, the treatment available today is limited and sometimes ineffective. Under this scenery, the Fragment-Based Drug Discovery (FBDD) emerged as one of the most promising alternatives to the traditional methods of drug development. This method allows achieving new lead compounds with smaller size of fragment libraries. Even with the wide Fragment-Based Drug Discovery success resulting in new effective therapeutic agents against different diseases, until this moment few studies have been applied this approach for NDs area...
May 26, 2017: Chemical Biology & Drug Design
https://www.readbyqxmd.com/read/28544198/jaboticaba-berry-peel-intake-prevents-insulin-resistance-induced-tau-phosphorylation-in-mice
#4
Ângela G Batista, Edilene S Soares, Monique C P Mendonça, Juliana K da Silva, Ana Paula Dionísio, Cesar R Sartori, Maria Alice da Cruz-Höfling, Mário R Maróstica Júnior
The hyperphosphorylation of tau in the hippocampus can be caused by central and peripheral insulin resistance and these alterations are related to the development of tauopathies, such as Alzheimer's disease. In this study, we used a high-fat diet to induce obesity and insulin resistance in adult Swiss mice and checked whether supplementation with Myrciaria jaboticaba berry peel for 10 weeks could improve insulin sensitivity, learning/memory performance and prevent tau phosphorylation in the hippocampus. Furthermore, adipocytokines, inflammatory markers, and oxidative stress were assessed...
May 19, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28543409/synergic-and-antagonistic-relationship-between-mmp-2-and-mmp-9-with-fibrosis-and-inflammation-in-chagas-cardiomyopathy
#5
REVIEW
Nayara I Medeiros, Juliana A S Gomes, Rodrigo Correa-Oliveira
Cardiomyopathy is the most important clinical manifestation in the chronic phase of Chagas disease because of its frequency, severity and impact on morbidity and mortality. The extracellular matrix degradation during cardiac remodeling in Trypanosoma cruzi infection is driven by matrix metalloproteinases (MMPs), primarily the MMP-2 and MMP-9 gelatinases. MMPs also regulate some molecules related to inflammation, such as growth factors, cytokines, and chemokines. The involvement of MMP-2 and MMP-9 is not yet fully understood in Chagas disease...
May 24, 2017: Parasite Immunology
https://www.readbyqxmd.com/read/28542438/chemically-induced-disseminated-pythiosis-in-balb-c-mice-a-new-experimental-model-for-pythium-insidiosum-infection
#6
Juliana S M Tondolo, Érico S Loreto, Pauline C Ledur, Francielli P K Jesus, Taiara M Silva, Glaucia D Kommers, Sydney H Alves, Janio M Santurio
Pythiosis is a severe and life-threatening disease that affects humans and various animal species. We report a model of vascular/disseminated pythiosis occurring after subcutaneous inoculation of 2 x 104 Pythium insidiosum zoospores/mL in immunocompromised BALB/c mice. For this model, we carried out two rounds of experiments. First, we evaluated two protocols of immunosuppression before inoculation: cyclophosphamide at 150 mg/kg (CYP group) and cyclophosphamide 200 mg/kg plus hydrocortisone acetate at 250 mg/kg (CYP+HCA group)...
2017: PloS One
https://www.readbyqxmd.com/read/28540750/neurobiology-of-emotions-an-update
#7
Vanderson Esperidião-Antonio, Marilia Majeski-Colombo, Diana Toledo-Monteverde, Glaciele Moraes-Martins, Juliana José Fernandes, Marjorie Bauchiglioni de Assis, Stefânia Montenegro, Rodrigo Siqueira-Batista
The 'nature' of emotions is one of the archaic themes of Western thought, thematized in different cultural manifestations - such as art, science, philosophy, myths and religion -, since Ancient times. In the last decades, the advances in neurosciences have permitted the construction of hypotheses that explain emotions, especially through the studies involving the limbic system. To present an updated discussion about the neurobiology of processes relating to emotions - focusing (1) on the main neural structures that relate to emotions, (2) the paths and circuits of greater relevance, (3) the implicated neurotransmitters, (4) the connections that possess neurovegetative control and (5) the discussion about the main emotions - is the objective of this present article...
May 25, 2017: International Review of Psychiatry
https://www.readbyqxmd.com/read/28540666/evaluation-of-mitochondrial-respiratory-function-in-highly-glycolytic-glioma-cells-reveals-low-adp-phosphorylation-in-relation-to-oxidative-capacity
#8
Erika Rodrigues-Silva, Edilene S Siqueira-Santos, Juliana S Ruas, Raffaela S Ignarro, Tiago R Figueira, Fábio Rogério, Roger F Castilho
High-grade gliomas are aggressive and intensely glycolytic tumors. In the present study, we evaluated the mitochondrial respiratory function of glioma cells (T98G and U-87MG) and fresh human glioblastoma (GBM) tissue. To this end, measurements of oxygen consumption rate (OCR) were performed under various experimental conditions. The OCR of T98G and U-87MG cells was well coupled to ADP phosphorylation based on the ratio of ATP produced per oxygen consumed of ~2.5. In agreement, the basal OCR of GBM tissue was also partially associated with ADP phosphorylation...
May 24, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28540546/environmental-risk-assessment-in-five-rivers-of-parana-river-basin-southern-brazil-through-biomarkers-in-astyanax-spp
#9
Ivaldete Tijolin Barros, Juliana Parolin Ceccon, Andressa Glinski, Samuel Liebel, Sonia Regina Grötzner, Marco Antonio Ferreira Randi, Evanilde Benedito, Claudia Feijó Ortolani-Machado, Francisco Filipak Neto, Ciro Alberto de Oliveira Ribeiro
In the current study, water quality of five river sites in Parana River basin (Brazil), utilized for public water supply, was assessed through a set of biomarkers in fish Astyanax spp. Population growth and inadequate use of land are challenges to the preservation of biodiversity and resources such as water. Some physicochemical parameters as well as somatic indexes, gills and liver histopathology, genotoxicity, and biochemical biomarkers were evaluated. The highest gonadosomatic index (GSI) and antioxidant parameters (catalase and glutathione S-transferase activities, non-protein thiols), as well as the lowest damage to biomolecules (lipid peroxidation, protein carbonylation, DNA damage) were observed in site 0 (Piava River), which is located at an environmental protected area...
May 24, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28539353/crf-and-urocortin-3-protect-the-heart-from-hypoxia-reoxygenation-induced-apoptosis-in-zebrafish
#10
Tegan A Williams, Jillian C Bergstrome, Juliana Scott, Nicholas J Bernier
Fish routinely experience environmental hypoxia and have evolved various strategies to tolerate this challenge. Given the key role of the corticotropin-releasing factor (CRF) system in coordinating the response to stressors and its cardioprotective actions against ischemia in mammals, we sought to characterize the cardiac CRF system in zebrafish and its role in hypoxia tolerance. We established that all genes of the CRF system, the ligands CRFa, CRFb, urotensin 1 (UTS1) and urocortin 3 (UCN3), the two receptor subtypes (CRFR1 and CRFR2), and the binding protein (CRFBP) are expressed in the heart of zebrafish: crfr1 > crfr2 = crfbp > crfa > ucn3 > crfb > uts1...
May 24, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28539258/dietary-approaches-to-stop-hypertension-diet-weight-status-and-blood-pressure-among-children-and-adolescents-national-health-and-nutrition-examination-surveys-2003-2012
#11
Juliana F W Cohen, Megan E Lehnerd, Robert F Houser, Eric B Rimm
BACKGROUND: The Dietary Approaches to Stop Hypertension (DASH) diet is associated with lower blood pressure and reduced risk of cardiovascular disease among adults, but little is known about accordance with this dietary pattern or health benefits among children and adolescents. OBJECTIVE: The objectives were to evaluate accordance with the DASH diet, differences over time, and the association with health attributes among a nationally representative sample of US children and adolescents...
May 20, 2017: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/28538891/hidroacanthoma-simplex-dermoscopy-and-cryosurgery-treatment
#12
Karina Colossi Furlan, Priscila Kakizaki, Juliana Cabral Nunes Chartuni, José Alexandre Sittart, Neusa Yuriko Sakai Valente
Hidroacanthoma simplex is a rare intraepidermal neoplasia that arises from the acrosyringial portion of the eccrine duct. Malignant transformation of hidroacanthoma simplex is reported in the literature and the treatment is performed with wide excision or Mohs micrographic surgery. We report the first case successfully treated with cryosurgery with a long-term follow up.
March 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28538867/preval%C3%A3%C2%AAncia-de-infec%C3%A3-%C3%A3-o-por-helicobacter-pylori-em-uma-comunidade-ind%C3%A3-gena-em-s%C3%A3-o-paulo-e-fatores-associados-estudo-transversalprevalence-of-helicobacter-pylori-infection-in-an-indigenous-community-in-s%C3%A3-o-paulo-and-associated-factors-cross-sectional-study
#13
Juliana Rejane da Silva Roque, Rodrigo Strehl Machado, Douglas Rodrigues, Patrícia Rech, Elisabete Kawakami
CONTEXT AND OBJECTIVE: The prevalence of Helicobacter pylori infection is unevenly distributed among different populations. The aim here was to evaluate the factors associated with Helicobacter pylori infection among children up to five years of age living in a high-risk community. DESIGN AND SETTING: Cross-sectional study in an indigenous community of Guarani Mbya ethnicity, Tekoa Ytu and Tekoa Pyau villages, Jaraguá district, city of São Paulo (SP), Brazil. METHODS: 74 children aged 0...
March 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/28538800/effect-of-aqueous-extract-of-the-leaves-of-baccharis-trimera-on-the-proliferation-of-hepatocytes-after-partial-hepatectomy-in-rats
#14
Sonia Oliveira Lima, Maria Bernadete Galrão de Almeida Figueiredo, Vanessa Rocha de Santana, Danillo Primo Andrade Santana, Matheus de Souza Nogueira, Erick Sobral Porto, Renata Lima Batalha de Andrade, Jessica Macêdo Santos, Ricardo Luiz Cavalcanti de Albuquerque, Juliana Cordeiro Cardoso
Purpose: To evaluate the effect of aqueous extract of Baccharis trimera leaves on the proliferative capacity of the liver after partial hepatectomy (PH) in rats. Methods: Twenty Wistar rats weighing between 300 and 450g were divided into two groups: control (HP) and test (HP100-rats that received the aqueous extract of Baccharis trimera for four days at a dose of 100 mg / kg / day). On the fifth day, animals from both groups underwent resection of 70% of the liver...
April 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/28538794/gender-differences-and-psychotropic-polypharmacy-in-psychiatric-patients-in-brazil-a-cross-sectional-analysis-of-the-pessoas-project
#15
Juliana de Oliveira Costa, Maria das Graças Braga Ceccato, Ana Paula Souto Melo, Francisco de Assis Acurcio, Mark Drew Crosland Guimarães
We aimed to estimate the prevalence and correlates of psychotropic polypharmacy in Brazilian psychiatric patients by gender. Sociodemographic, behavioral and clinical data were obtained through face-to-face interviews and medical charts of 2,475 patients. Psychotropic polypharmacy was defined as the use of two or more psychotropic drugs and occurred in 85.7% of men (95%CI: 83.6%-87.6%) and 84.9% of women (95%CI: 82.8%-86.8%; p > 0.05). The mean number of psychotropic drugs/patient was 2.98 ± 1.23 and most common combinations included antipsychotics...
May 18, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28538775/a-murine-model-of-elastase-and-cigarette-smoke-induced-emphysema
#16
Rubia Rodrigues, Clarice Rosa Olivo, Juliana Dias Lourenço, Alyne Riane, Daniela Aparecida de Brito Cervilha, Juliana Tiyaki Ito, Milton de Arruda Martins, Fernanda Degobbi Tenório Quirino Dos Santos Lopes
Objective: To describe a murine model of emphysema induced by a combination of exposure to cigarette smoke (CS) and instillation of porcine pancreatic elastase (PPE). Methods: A total of 38 C57BL/6 mice were randomly divided into four groups: control (one intranasal instillation of 0.9% saline solution); PPE (two intranasal instillations of PPE); CS (CS exposure for 60 days); and CS + PPE (two intranasal instillations of PPE + CS exposure for 60 days). At the end of the experimental protocol, all animals were anesthetized and tracheostomized for calculation of respiratory mechanics parameters...
March 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/28538773/propensity-scores-a-tool-to-help-quantify-treatment-effects-in-observational-studies
#17
Cecilia Maria Patino, Juliana Carvalho Ferreira
No abstract text is available yet for this article.
March 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/28538761/effects-of-continuous-and-accumulated-exercise-on-endothelial-function-in-rat-aorta
#18
Juliana Edwiges Martinez, Elane de Fátima Taipeiro, Agnaldo Bruno Chies
Background: The practice of exercise in short bouts repeated throughout the day may be an alternative strategy to lift people out of physical inactivity. Objective: to evaluate if accumulated exercise, as occurs in continuous exercise training, improve endothelial function in rat aorta. Methods: Wistar male rats were divided into three groups: continuous exercise (CEx, 1 hour on the treadmill) or accumulated exercise (AEx, 4 bouts of 15 minutes / day) for 5 days/week for 8 weeks, or sedentary (SED)...
April 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28538018/low-serum-angiopoietin-1-high-serum-angiopoietin-2-and-high-ang-2-ang-1-protein-ratio-are-associated-with-early-onset-sepsis-in-surinamese-newborns
#19
Rens Zonneveld, Rianne Jongman, Amadu Juliana, Wilco Zijlmans, Frans Plötz, Grietje Molema, Matijs van Meurs
PURPOSE: Vascular inflammation and leakage in sepsis is mediated by Angiopoietin-1 (Ang-1) and -2 (Ang-2) and their phosphorylation of the endothelial Tie-2 receptor. Levels of Ang-2 change in adults and children during sepsis, which is associated with severity of sepsis. This study investigates levels of Ang-1 and Ang-2 in newborns to gain insight in the vascular pathophysiology of early onset sepsis (EOS) within 72 hours after birth. METHODS: A prospective cohort study was performed amongst 71 Surinamese newborns treated with antibiotics for suspected EOS and 20 control newborns...
May 22, 2017: Shock
https://www.readbyqxmd.com/read/28537550/household-transmission-of-invasive-group-a-streptococcus-infections-in-england-a-population-based-study-2009-2011-to-2013
#20
Rachel Mearkle, Maria Saavedra-Campos, Theresa Lamagni, Martine Usdin, Juliana Coelho, Vicki Chalker, Shiranee Sriskandan, Rebecca Cordery, Chas Rawlings, Sooria Balasegaram
Invasive group A streptococcal infection has a 15% case fatality rate and a risk of secondary transmission. This retrospective study used two national data sources from England; enhanced surveillance (2009) and a case management system (2011-2013) to identify clusters of severe group A streptococcal disease. Twenty-four household pairs were identified. The median onset interval between cases was 2 days (range 0-28) with simultaneous onset in eight pairs. The attack rate during the 30 days after first exposure to a primary case was 4,520 per 100,000 person-years at risk (95% confidence interval (CI): 2,900-6,730) a 1,940 (95% CI: 1,240-2,880) fold elevation over the background incidence...
May 11, 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
keyword
keyword
105014
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"