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https://www.readbyqxmd.com/read/28324816/sex-differences-and-hormonal-modulation-of-ethanol-enhanced-risk-taking-in-rats
#1
Kathryn G Wallin-Miller, Jordyn Chesley, Juliana Castrillon, Ruth I Wood
BACKGROUND: Ethanol (EtOH) intake correlates with increased risk-taking, and sex differences exist in both EtOH use and risk-taking in humans and rats. However, the interaction of sex and gonadal hormones to affect risk-taking under the influence of EtOH has not been determined. This was the focus of the current study. METHODS: Adult Long-Evans rats (n=18 males and females) were gonadectomized and received hormone replacement at physiologic levels or blank implants (n=7-9/group)...
March 7, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28319694/sexual-trauma-is-more-strongly-associated-with-tonic-immobility-than-other-types-of-trauma-a-population-based-study
#2
Juliana Kalaf, Evandro Silva Freire Coutinho, Liliane Maria Pereira Vilete, Mariana Pires Luz, William Berger, Mauro Mendlowicz, Eliane Volchan, Sergio Baxter Andreoli, Maria Inês Quintana, Jair de Jesus Mari, Ivan Figueira
BACKGROUND: Tonic immobility is an involuntary motor and vocal inhibition reaction, considered the last-ditch response of the defensive cascade model. It is elicited in context of inescapable threat and perception of entrapment. Our aim was to investigate the association between different traumatic events and peritraumatic tonic immobility (PTI) in a representative sample of the general population. METHODS: This is a cross-sectional study of general population from Rio de Janeiro and São Paulo with 3231 victims of traumatic events aged 15-75 years who completed the Tonic Immobility Scale (TIS)...
March 7, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28318559/screening-level-risk-assessment-applied-to-dredging-of-polluted-sediments-from-guanabara-bay-rio-de-janeiro-brazil
#3
Ana Elisa F Silveira, Juliana R Nascimento, Elisamara Sabadini-Santos, Edison D Bidone
Guanabara Bay is characterized by predominant eutrophication and anoxic sediments with a mixture of pollutants. The risk prognosis associated with the dumping of its dredged sediments into the open ocean was addressed by our algorithm. Our algorithm could prioritize areas, characterize major processes related to dredging, measure the potential risk of sediments, and predict the effects of sediment mixing. The estimated risk of dredged sediment was >10-fold than that of ocean sediments. Among metals, mercury represented 50-90% of the total risk...
March 16, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28317778/physicochemical-and-sensory-aroma-and-colour-characterisation-of-a-non-centrifugal-cane-sugar-panela-beverage
#4
Juliana María García, Paulo César Narváez, Francisco José Heredia, Álvaro Orjuela, Coralia Osorio
Non-centrifugal cane sugar (NCS), also called "panela", is a high carbohydrate-content food obtained by boil evaporation of the sugar cane juice. This study was undertaken to assess physicochemical properties and sensory characteristics of panela beverage at two different concentrations. Evaluation of pH, °Brix, and colour (tristimulus colorimetry) was carried out in all panela drink samples. In order to characterise the odour-active volatiles of the beverage, a simultaneous steam distillation-solvent extraction method was applied using a mixture of diethyl ether-pentane (1:1,w/w) as solvent...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28317494/pathogenic-potential-and-genotypic-diversity-of-campylobacter-jejuni-a-neglected-food-borne-pathogen-in-brazil
#5
Miliane Rodrigues Frazão, Marta Inês Cazentini Medeiros, Sheila da Silva Duque, Juliana Pfrimer Falcão
Purpose and methodology.Campylobacter jejuni is a major zoonotic pathogen that causes food-borne gastroenteritis worldwide. However, there are only a few studies available that have molecularly characterized C. jejuni strains isolated in Brazil. The aim of this study was to genotype 111 C. jejuni strains isolated from sick humans (43), monkey faeces (19), chicken faeces (14), chicken meat (33) and sewage (2) between 1996 and 2016 in Brazil using flaA-SVR (short variable region) sequencing and PFGE. Furthermore, the presence of 16 virulence genes was analysed by PCR...
March 20, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28306733/hypervirulent-mycobacterium-tuberculosis-strain-triggers-necrotic-lung-pathology-associated-with-enhanced-recruitment-of-neutrophils-in-resistant-c57bl-6-mice
#6
Fabrício M Almeida, Thatiana L B Ventura, Eduardo P Amaral, Simone C M Ribeiro, Sanderson D Calixto, Marcelle R Manhães, Andreza L Rezende, Giliane S Souzal, Igor S de Carvalho, Elisangela C Silva, Juliana Azevedo da Silva, Eulógio C Q Carvalho, Afranio L Kritski, Elena B Lasunskaia
Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis (Mtb) that in most cases induces irreversible necrosis of lung tissue as a result of excessive inflammatory reactions. The murine model of TB in resistant C57BL/6 mice infected with reference Mtb strains is widely used in TB studies; however, these mice do not show a necrotic pathology, which restricts their use in studies of irreversible tissue damage. Recently, we demonstrated that necrotic lung lesions could be induced in the C57BL/6 mice by highly virulent Mtb strains belonging to the modern Beijing sublineage...
2017: PloS One
https://www.readbyqxmd.com/read/28304073/the-plant-cell-cycle-pre-replication-complex-formation-and-controls
#7
Juliana Nogueira Brasil, Carinne N Monteiro Costa, Luiz Mors Cabral, Paulo C G Ferreira, Adriana S Hemerly
The multiplication of cells in all living organisms requires a tight regulation of DNA replication. Several mechanisms take place to ensure that the DNA is replicated faithfully and just once per cell cycle in order to originate through mitoses two new daughter cells that contain exactly the same information from the previous one. A key control mechanism that occurs before cells enter S phase is the formation of a pre-replication complex (pre-RC) that is assembled at replication origins by the sequential association of the origin recognition complex, followed by Cdt1, Cdc6 and finally MCMs, licensing DNA to start replication...
March 16, 2017: Genetics and Molecular Biology
https://www.readbyqxmd.com/read/28304067/lipid-remodelling-in-human-melanoma-cells-in-response-to-uva-exposure
#8
Elisabete Maciel, Juliana Felgueiras, Eduarda M P Silva, Fernando Ricardo, Ana S P Moreira, Tânia Melo, Ana Campos, Margarida Fardilha, Pedro Domingues, M Rosário Domingues
Extensive exposure to UVA is thought to increase the risk of malignancy and the progression of melanoma, the most serious type of skin cancer. It is well known that alterations in lipid metabolism represent an early event in carcinogenesis, but the impact of UVA exposure on the lipid composition of cancer cells is still largely unknown. In this study we aimed at investigating lipid remodeling in human melanoma cells in response to UVA exposure. After UVA irradiation, lipid extracts were either immediately collected from SK-MEL-28 cells or collected after a recovery period of 2 h or 24 h...
March 17, 2017: Photochemical & Photobiological Sciences
https://www.readbyqxmd.com/read/28303542/sorption-and-desorption-of-silver-ions-by-bentonite-clays
#9
Leonel Vinicius Constantino, Juliana Nunes Quirino, Alessandra Maffei Monteiro, Taufik Abrão, Paulo Sérgio Parreira, Alexandre Urbano, Maria Josefa Santos
Anthropogenic activities have increased the concentration of metal species in the environment. The toxicity of silver ions to aquatic and terrestrial organisms has required monitoring by analytical methods, besides actions to promote its control as pollutant. Sorption and desorption processes are directly related to the mobility and availability of metal ions in the environment. In this context, clay minerals can be used for pre-concentration, removal and recovery of silver ions from aqueous solution. Herein, two bentonite clays (BaVC-1 and SWy-2) were characterised and applied to investigate the sorption and desorption of silver ions...
March 17, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28303200/atypical-neuroleptic-malignant-syndrome-associated-with-use-of-clozapine
#10
Quevedo-Florez Leonardo, Granada-Romero Juliana, Camargo-Arenas Juan Fernando
The Neuroleptic Malignant Syndrome (NMS) is a medical emergency of infrequent presentation in the emergency department, which is associated with the use of psychiatric drugs, such as typical and atypical antipsychotics. Our case addresses a 55-year-old patient diagnosed with undifferentiated schizophrenia for 10 years, who had been receiving clozapine and clonazepam as part of their treatment. This patient presents the symptoms of Neuroleptic Malignant Syndrome without fever, which improves with treatment especially with the withdrawal of clozapine...
2017: Case Reports in Emergency Medicine
https://www.readbyqxmd.com/read/28303121/identification-of-lama-glama-as-reservoirs-for-acinetobacter-lwoffii
#11
Martín M Ledesma, Ailén M Díaz, Claudia Barberis, Carlos Vay, Marcela A Manghi, Juliana Leoni, Marisa S Castro, Alejandro Ferrari
South American Camelids have an increasing relevance in local economies, worldwide. These animals are bred for their meat, fur and as companion and therapy animals. Thus, their sanitary status should be well-established. According to the OIE (World Organization for Animal Health), respiratory infections mainly produced by Pasteurella spp. have been reported for camelids. It has been stated that this microorganism causes a mild disease, although many authors report it is an important cause of mortality among alpacas...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28302860/mobile-mute-specifies-subsidiary-cells-to-build-physiologically-improved-grass-stomata
#12
Michael T Raissig, Juliana L Matos, M Ximena Anleu Gil, Ari Kornfeld, Akhila Bettadapur, Emily Abrash, Hannah R Allison, Grayson Badgley, John P Vogel, Joseph A Berry, Dominique C Bergmann
Plants optimize carbon assimilation while limiting water loss by adjusting stomatal aperture. In grasses, a developmental innovation-the addition of subsidiary cells (SCs) flanking two dumbbell-shaped guard cells (GCs)-is linked to improved stomatal physiology. Here, we identify a transcription factor necessary and sufficient for SC formation in the wheat relative Brachypodium distachyon. Unexpectedly, the transcription factor is an ortholog of the stomatal regulator AtMUTE, which defines GC precursor fate in Arabidopsis The novel role of BdMUTE in specifying lateral SCs appears linked to its acquisition of cell-to-cell mobility in Brachypodium Physiological analyses on SC-less plants experimentally support classic hypotheses that SCs permit greater stomatal responsiveness and larger range of pore apertures...
March 17, 2017: Science
https://www.readbyqxmd.com/read/28302577/methamphetamine-effects-on-the-brain-gut-and-immune-system
#13
REVIEW
Monica D Prakash, Kathy Tangalakis, Juliana Antonipillai, Lily Stojanovska, Kulmira Nurgali, Vasso Apostolopoulos
Methamphetamine (METH) is a powerful central nervous system stimulant which elevates mood, alertness, energy levels and concentration in the short-term. However, chronic use and/or at higher doses METH use often results in psychosis, depression, delusions and violent behavior. METH was formerly used to treat conditions such as obesity and attention deficit hyperactivity disorder, but now is primarily used recreationally. Its addictive nature has led to METH abuse becoming a global problem. At a cellular level, METH exerts a myriad of effects on the central and peripheral nervous systems, immune system and the gastrointestinal system...
March 13, 2017: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/28302074/clonality-outer-membrane-proteins-profile-and-efflux-pump-in-kpc-producing-enterobacter-sp-in-brazil
#14
Juliana Ferraz Rosa, Camila Rizek, Ana Paula Marchi, Thais Guimaraes, Lourdes Miranda, Claudia Carrilho, Anna S Levin, Silvia F Costa
BACKGROUND: Carbapenems resistance in Enterobacter spp. has increased in the last decade, few studies, however, described the mechanisms of resistance in this bacterium. This study evaluated clonality and mechanisms of carbapenems resistance in clinical isolates of Enterobacter spp. identified in three hospitals in Brazil (Hospital A, B and C) over 7-year. METHODS: Antibiotics sensitivity, pulsed-field gel electrophoresis (PFGE), PCR for carbapenemase and efflux pump genes were performed for all carbapenems-resistant isolates...
March 17, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28301583/correction-cardiovascular-variability-analysis-and-baroreflex-estimation-in-patients-with-type-2-diabetes-in-absence-of-any-manifest-neuropathy
#15
Sílvia Cristina Garcia de Moura-Tonello, Alberto Porta, Andrea Marchi, Alessandra de Almeida Fagundes, Cristina de Oliveira Francisco, Patrícia Rehder-Santos, Juliana Cristina Milan-Mattos, Rodrigo Polaquini Simões, Mariana de Oliveira Gois, Aparecida Maria Catai
[This corrects the article DOI: 10.1371/journal.pone.0148903.].
2017: PloS One
https://www.readbyqxmd.com/read/28301154/consistent-principal-component-modes-from-molecular-dynamics-simulations-of-proteins
#16
Rodrigo Cossio-Pérez, Juliana Palma, Gustavo Pierdominici-Sottile
Principal component analysis is a technique widely used for studying the movements of proteins using data collected from molecular dynamics simulations. In spite of its extensive use the technique has a serious drawback: equivalent simulations do not afford the same PC-modes. In this article we show that concatenating equivalent trajectories and calculating the PC-modes from the concatenated one significantly enhances the reproducibility of the results. Moreover, the consistency of the modes can be systematically improved by adding more individual trajectories to the concatenated one...
March 16, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/28300994/the-choking-game-a-new-craze-among-brazilian-children-and-young-people-psychophysiological-behavioral-and-epidemiological-characteristics-of-asphyxial-games
#17
Juliana Guilheri, Anne Andronikof, Latife Yazigi
The 'choking game' is a risk-taking behavior that has spread quickly among children and young people, causing dependence, accidents and even death, including in Brazil. These activities are performed in order to experience fleeting euphoric sensations, attracting numerous participants through the thousands of videos posted on YouTube. The problem of 'asphyxial games' can be observed in the Brazilian digital media, although there is a lack of scientific studies. Through a systematic review of the literature and complementary material, this paper aims to address the 'asphyxial games', warning about the psychophysiological and behavioral effects of these practices, while also presenting international epidemiological data...
March 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28300930/gianotti-crosti-syndrome-a-case-report-of-a-teenager
#18
Renata Leite Pedreira, Juliana Martins Leal, Keline Jácome Silvestre, Alice Paixão Lisboa, Alexandre Carlos Gripp
Gianotti-Crosti syndrome is a rare disease characterized by acral papular eruption with symmetrical distribution. It is a benign and self-limited disease; the symptoms disappear after two to eight weeks, without recurrences or scars. Skin lesions are usually asymptomatic. Prodrome might occur, suggesting upper respiratory infection, or constitutional symptoms. Diagnosis is eminently clinical, and this disease is associated with viral infections. Due to its rarity and low occurrence in adolescents and adults, we report a case of Gianotti-Crosti syndrome of a teenager...
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28300893/steatocystoma-multiplex-suppurativa-case-report-of-a-rare-condition
#19
Cândida Naira Lima E Lima Santana, Daniele do Nascimento Pereira, Alice Paixão Lisboa, Juliana Martins Leal, Daniel Lago Obadia, Roberto Souto da Silva
Steatocystoma multiplex is a rare genetic disorder characterized by the presence of hamartomatous malformations at the junction of the pilosebaceous duct. It consists of encapsulated cystic lesions in the dermis, with adjacent sebaceous gland. When associated with inflammation, resembling hidradenitis, it is called steatocystoma multiplex suppurativa, a condition rarely reported. This is the first case of steatocystoma multiplex suppurativa reported in the Brazilian literature. Female patient, 23 years old, with papular and nodular cystic lesions that started in the armpits and groin, later spreading to the trunk, lower limbs, anticubital fossa, face and scalp...
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28300891/lichen-planopilaris-like-eruption-during-treatment-with-tyrosine-kinase-inhibitor-nilotinib
#20
Juliana Ribeiro Leitão, Neusa Yuriko Sakai Valente, Priscila Kakizaki, Isis Suga Veronez, Mario Cezar Pires
Tyrosine kinase inhibitors are effective as a target therapy for malignant neoplasms. Imatinib was the first tyrosine kinase inhibitor used. After its introduction, several other drugs have appeared with a similar mechanism of action, but less prone to causing resistance. Even though these drugs are selective, their toxicity does not exclusively target cancer cells, and skin toxicity is the most common non-hematologic adverse effect. We report an eruption similar to lichen planopilaris that developed during therapy with nilotinib, a second generation tyrosine kinase inhibitor, in a patient with chronic myeloid leukemia resistant to imatinib...
September 2016: Anais Brasileiros de Dermatologia
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