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Lin H Bailey, Deborah O Jeffries, Jason J Bailey, Renee W Pinsky, Janet E Bailey, Bin Nan, Tianwen Ma, Katherine A Klein
PURPOSE: Our aim was to assess and address the challenges radiology residents face when managing breast imaging emergencies on call and to determine if targeted educational interventions improved resident confidence and knowledge. METHODS: We created surveys to determine resident comfort level with and knowledge of appropriate management of breast imaging emergencies. We also created structured educational interventions to improve resident confidence and knowledge...
March 3, 2018: Emergency Radiology
Sabrina Arshed, Michael R Pinsky
Fluids during resuscitation from shock increase mean systemic pressure and venous return. The pressure gradient for venous return must increase. Mean systemic pressure is the amount of vascular space in unstressed and stressed volume, mostly unstressed. Shock states can decrease mean systemic pressure by increasing unstressed volume, decreasing total blood volume, or decreasing the pressure gradient for venous return. Crystalloids across bodily spaces restore normal volume, whereas colloids remain in the intravascular space...
April 2018: Critical Care Clinics
Anna E Jaffe, Kaitlin E Bountress, Isha W Metzger, Jessica L Maples-Keller, Hanna T Pinsky, William H George, Amanda K Gilmore
INTRODUCTION: The purpose of this study was to investigate individual engagement and comfort during a web-based intervention for alcohol and sexual assault risk reduction. METHODS: Participants were 264 college women (aged 18-20) who reported engaging in heavy episodic drinking in the past month. Participants were randomized to either an intervention condition (alcohol, sexual assault risk reduction, or combined) or a control condition (full or minimal assessment)...
February 14, 2018: Addictive Behaviors
Hagit Bar-Yosef, Tsvia Gildor, Bernardo Ramírez-Zavala, Christian Schmauch, Ziva Weissman, Mariel Pinsky, Rawi Naddaf, Joachim Morschhäuser, Robert A Arkowitz, Daniel Kornitzer
The human pathogenic fungus Candida albicans can switch between yeast and hyphal morphologies as a function of environmental conditions and cellular physiology. The yeast-to-hyphae morphogenetic switch is activated by well-established, kinase-based signal transduction pathways that are induced by extracellular stimuli. In order to identify possible inhibitory pathways of the yeast-to-hyphae transition, we interrogated a collection of C. albicans protein kinases and phosphatases ectopically expressed under the regulation of the TETon promoter...
2018: Frontiers in Cellular and Infection Microbiology
Sarah Cobey, Sigrid Gouma, Kaela Parkhouse, Benjamin S Chambers, Hildegund C Ertl, Kenneth E Schmader, Rebecca A Halpin, Xudong Lin, Timothy B Stockwell, Suman R Das, Emily Landon, Vera Tesic, Ilan Youngster, Benjamin A Pinsky, David E Wentworth, Scott E Hensley, Yonatan H Grad
Background: Influenza vaccination aims to prevent infection by influenza virus and reduce associated morbidity and mortality; however, vaccine effectiveness (VE) can be modest, especially for subtype A(H3N2). Low VE has been attributed to mismatches between the vaccine and circulating influenza strains and to the vaccine's elicitation of protective immunity in only a subset of the population. The low H3N2 VE in the 2012-2013 season was attributed to egg-adaptive mutations that created antigenic mismatch between the actual vaccine strain (IVR-165) and both the intended vaccine strain (A/Victoria/361/2011) and the predominant circulating strains (clades 3C...
February 20, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
D De Backer, M Pinsky
No abstract text is available yet for this article.
March 2018: British Journal of Anaesthesia
Malin L Pinsky
No abstract text is available yet for this article.
February 12, 2018: Proceedings of the National Academy of Sciences of the United States of America
Can Ince, E Christiaan Boerma, Maurizio Cecconi, Daniel De Backer, Nathan I Shapiro, Jacques Duranteau, Michael R Pinsky, Antonio Artigas, Jean-Louis Teboul, Irwin K M Reiss, Cesar Aldecoa, Sam D Hutchings, Abele Donati, Marco Maggiorini, Fabio S Taccone, Glenn Hernandez, Didier Payen, Dick Tibboel, Daniel S Martin, Alexander Zarbock, Xavier Monnet, Arnaldo Dubin, Jan Bakker, Jean-Louis Vincent, Thomas W L Scheeren
PURPOSE: Hand-held vital microscopes (HVMs) were introduced to observe sublingual microcirculatory alterations at the bedside in different shock states in critically ill patients. This consensus aims to provide clinicians with guidelines for practical use and interpretation of the sublingual microcirculation. Furthermore, it aims to promote the integration of routine application of HVM microcirculatory monitoring in conventional hemodynamic monitoring of systemic hemodynamic variables...
February 6, 2018: Intensive Care Medicine
Mark A Pinsky
OBJECTIVE : The purpose of this study was to evaluate the efficacy of five topical test products intended to reduce the appearance of lines and wrinkles, increase skin moisturization, and reduce transepidermal water loss. DESIGN : Two studies-a controlled clinical trial for each individual test product and an experience trial involving more than 200 patients using a strategic combination of products-were done. Test products included a day facial cream, a night facial cream, an eye cream, a day lip cream, and a night lip cream...
December 2017: Journal of Clinical and Aesthetic Dermatology
Deborah M Rooney, David M Hananel, Benjamin J Covington, Patrick L Dionise, Michael T Nykamp, Melvin Pederson, Jamal M Sahloul, Rachael Vasquez, F Jacob Seagull, Harold M Pinsky, Domenica G Sweier, James M Cooke
BACKGROUND: Currently there is no reliable, standardized mechanism to support health care professionals during the evaluation of and procurement processes for simulators. A tool founded on best practices could facilitate simulator purchase processes. METHODS: In a 3-phase process, we identified top factors considered during the simulator purchase process through expert consensus (n = 127), created the Simulator Value Index (SVI) tool, evaluated targeted validity evidence, and evaluated the practical value of this SVI...
January 18, 2018: Surgery
Peter Pinski, Frank Neese
Electron correlation methods based on pair natural orbitals (PNOs) have gained an increasing degree of interest in recent years, as they permit energy calculations to be performed on systems containing up to many hundred atoms, while maintaining chemical accuracy for reaction energies. We present an approach for taking exact analytical first derivatives of the energy contributions in the simplest method of the family of Domain-based Local Pair Natural Orbital (DLPNO) methods, closed-shell DLPNO-MP2. The Lagrangian function contains constraints to account for the relaxation of PNOs...
January 21, 2018: Journal of Chemical Physics
Akriti Gupta, Satendra Singh, Farah Khaliq, Upreet Dhaliwal, S V Madhu
In the country presently, preclinical medical students are not routinely exposed to real patients. Thus, when they start clinical postings, they are found to have poor clinical reasoning skills. Simulated virtual patients (SVPs) can improve clinical skills without endangering real patients. This pilot study describes the development of two SVPs in endocrine physiology and their validation in terms of acquisition of clinical knowledge and student engagement. Two SVPs, Nandini Sharma (unintentional weight gain) and Sunil Yadav (polyuria), were created and published on the i-Human Patients platform through an iterative, interdisciplinary, and transdisciplinary collaborative process using the conceptual framework of Kim et al...
March 1, 2018: Advances in Physiology Education
Kerry S O'Brien, Walter Forrest, Iain Greenlees, Daniel Rhind, Sophia Jowett, Ilana Pinsky, Albert Espelt, Marina Bosque-Prous, Anders Larrabee Sonderlund, Matteo Vergani, Muhammad Iqbal
OBJECTIVES: There is no research examining alcohol-related aggression and anti-social behaviour in UK or European sportspeople (athletes), and no research has examined relationships between masculinity, alcohol consumption, and alcohol-related aggression and antisocial behaviour in sportspeople (athletes). This study addresses this gap. DESIGN: Cross-sectional. METHODS: A sample (N=2048; women=892, 44%) of in season sportspeople enrolled at UK universities (response 83%), completed measures of masculinity, alcohol consumption, within-sport (on-field) violence, and having been the perpetrator and/or victim of alcohol-related violent/aggressive and antisocial behaviour (e...
July 4, 2017: Journal of Science and Medicine in Sport
Paul F Pinsky
No abstract text is available yet for this article.
January 17, 2018: Expert Review of Respiratory Medicine
Fabio Guarracino, Pietro Bertini, Michael R Pinsky
Hemodynamic monitoring is essential during the treatment of the critically ill in order to address the hemodynamic alterations and assess the response to treatment. Traditionally classified causes of shock and underlying pathophysiological mechanisms are often neglected by resuscitative strategies included in the guidelines. Most of hemodynamic management focuses on the ability to early recognise patients susceptible to increase cardiac output (CO) and mean arterial pressure (MAP) after a defined fluid challenge by eliciting Starling's law of the heart, and less is known of the ones presenting in shock and not volume responsive...
January 16, 2018: Minerva Anestesiologica
Sammy Saab, Darshan Mehta, Stacie Hudgens, Nathan Grunow, Yanjun Bao, Brett Pinsky
BACKGROUND AND AIMS: This study analyzes health related quality of life (HRQoL) data from 8 randomized clinical trials using ombitasvir/paritaprevir/ritonavir and dasabuvir (3D) ± ribavirin [RBV] to investigate: [1] the impact of the treatment vs. placebo during treatment on HRQoL; [2] the sustainability of such treatment effect after 12-week treatment period; and [3] if results from [1] and [2] differ in subgenotypes 1a vs. 1b. METHODS: Six registration trials and 2 post-approval trials were pooled and analyzed using longitudinal mixed models (MM) to estimate the effect of 3D + RBV on HRQoL outcomes adjusting for baseline scores, as well as patient demographics and clinical characteristics...
January 5, 2018: Liver International: Official Journal of the International Association for the Study of the Liver
S Acharya, D Adamová, J Adolfsson, M M Aggarwal, G Aglieri Rinella, M Agnello, N Agrawal, Z Ahammed, S U Ahn, S Aiola, A Akindinov, M Al-Turany, S N Alam, D S D Albuquerque, D Aleksandrov, B Alessandro, R Alfaro Molina, Y Ali, A Alici, A Alkin, J Alme, T Alt, L Altenkamper, I Altsybeev, C Alves Garcia Prado, C Andrei, D Andreou, H A Andrews, A Andronic, V Anguelov, C Anson, T Antičić, F Antinori, P Antonioli, R Anwar, L Aphecetche, H Appelshäuser, S Arcelli, R Arnaldi, O W Arnold, I C Arsene, M Arslandok, B Audurier, A Augustinus, R Averbeck, M D Azmi, A Badalà, Y W Baek, S Bagnasco, R Bailhache, R Bala, A Baldisseri, M Ball, R C Baral, A M Barbano, R Barbera, F Barile, L Barioglio, G G Barnaföldi, L S Barnby, V Barret, P Bartalini, K Barth, E Bartsch, N Bastid, S Basu, G Batigne, B Batyunya, P C Batzing, J L Bazo Alba, I G Bearden, H Beck, C Bedda, N K Behera, I Belikov, F Bellini, H Bello Martinez, R Bellwied, L G E Beltran, V Belyaev, G Bencedi, S Beole, A Bercuci, Y Berdnikov, D Berenyi, R A Bertens, D Berzano, L Betev, A Bhasin, I R Bhat, B Bhattacharjee, J Bhom, A Bianchi, L Bianchi, N Bianchi, C Bianchin, J Bielčík, J Bielčíková, A Bilandzic, G Biro, R Biswas, S Biswas, J T Blair, D Blau, C Blume, G Boca, F Bock, A Bogdanov, L Boldizsár, M Bombara, G Bonomi, M Bonora, J Book, H Borel, A Borissov, M Borri, E Botta, C Bourjau, L Bratrud, P Braun-Munzinger, M Bregant, T A Broker, M Broz, E J Brucken, E Bruna, G E Bruno, D Budnikov, H Buesching, S Bufalino, P Buhler, P Buncic, O Busch, Z Buthelezi, J B Butt, J T Buxton, J Cabala, D Caffarri, H Caines, A Caliva, E Calvo Villar, P Camerini, A A Capon, F Carena, W Carena, F Carnesecchi, J Castillo Castellanos, A J Castro, E A R Casula, C Ceballos Sanchez, S Chandra, B Chang, W Chang, S Chapeland, M Chartier, S Chattopadhyay, S Chattopadhyay, A Chauvin, C Cheshkov, B Cheynis, V Chibante Barroso, D D Chinellato, S Cho, P Chochula, M Chojnacki, S Choudhury, T Chowdhury, P Christakoglou, C H Christensen, P Christiansen, T Chujo, S U Chung, C Cicalo, L Cifarelli, F Cindolo, J Cleymans, F Colamaria, D Colella, A Collu, M Colocci, M Concas, G Conesa Balbastre, Z Conesa Del Valle, J G Contreras, T M Cormier, Y Corrales Morales, I Cortés Maldonado, P Cortese, M R Cosentino, F Costa, S Costanza, J Crkovská, P Crochet, E Cuautle, L Cunqueiro, T Dahms, A Dainese, M C Danisch, A Danu, D Das, I Das, S Das, A Dash, S Dash, S De, A De Caro, G de Cataldo, C de Conti, J de Cuveland, A De Falco, D De Gruttola, N De Marco, S De Pasquale, R D De Souza, H F Degenhardt, A Deisting, A Deloff, C Deplano, P Dhankher, D Di Bari, A Di Mauro, P Di Nezza, B Di Ruzza, M A Diaz Corchero, T Dietel, P Dillenseger, Y Ding, R Divià, Ø Djuvsland, A Dobrin, D Domenicis Gimenez, B Dönigus, O Dordic, L V R Doremalen, A K Dubey, A Dubla, L Ducroux, S Dudi, A K Duggal, M Dukhishyam, P Dupieux, R J Ehlers, D Elia, E Endress, H Engel, E Epple, B Erazmus, F Erhardt, B Espagnon, G Eulisse, J Eum, D Evans, S Evdokimov, L Fabbietti, J Faivre, A Fantoni, M Fasel, L Feldkamp, A Feliciello, G Feofilov, A Fernández Téllez, E G Ferreiro, A Ferretti, A Festanti, V J G Feuillard, J Figiel, M A S Figueredo, S Filchagin, D Finogeev, F M Fionda, M Floris, S Foertsch, P Foka, S Fokin, E Fragiacomo, A Francescon, A Francisco, U Frankenfeld, G G Fronze, U Fuchs, C Furget, A Furs, M Fusco Girard, J J Gaardhøje, M Gagliardi, A M Gago, K Gajdosova, M Gallio, C D Galvan, P Ganoti, C Garabatos, E Garcia-Solis, K Garg, C Gargiulo, P Gasik, E F Gauger, M B Gay Ducati, M Germain, J Ghosh, P Ghosh, S K Ghosh, P Gianotti, P Giubellino, P Giubilato, E Gladysz-Dziadus, P Glässel, D M Goméz Coral, A Gomez Ramirez, A S Gonzalez, V Gonzalez, P González-Zamora, S Gorbunov, L Görlich, S Gotovac, V Grabski, L K Graczykowski, K L Graham, L Greiner, A Grelli, C Grigoras, V Grigoriev, A Grigoryan, S Grigoryan, J M Gronefeld, F Grosa, J F Grosse-Oetringhaus, R Grosso, F Guber, R Guernane, B Guerzoni, K Gulbrandsen, T Gunji, A Gupta, R Gupta, I B Guzman, R Haake, C Hadjidakis, H Hamagaki, G Hamar, J C Hamon, M R Haque, J W Harris, A Harton, H Hassan, D Hatzifotiadou, S Hayashi, S T Heckel, E Hellbär, H Helstrup, A Herghelegiu, E G Hernandez, G Herrera Corral, F Herrmann, B A Hess, K F Hetland, H Hillemanns, C Hills, B Hippolyte, B Hohlweger, D Horak, S Hornung, R Hosokawa, P Hristov, C Hughes, T J Humanic, N Hussain, T Hussain, D Hutter, D S Hwang, S A Iga Buitron, R Ilkaev, M Inaba, M Ippolitov, M S Islam, M Ivanov, V Ivanov, V Izucheev, B Jacak, N Jacazio, P M Jacobs, M B Jadhav, S Jadlovska, J Jadlovsky, S Jaelani, C Jahnke, M J Jakubowska, M A Janik, P H S Y Jayarathna, C Jena, M Jercic, R T Jimenez Bustamante, P G Jones, A Jusko, P Kalinak, A Kalweit, J H Kang, V Kaplin, S Kar, A Karasu Uysal, O Karavichev, T Karavicheva, L Karayan, P Karczmarczyk, E Karpechev, U Kebschull, R Keidel, D L D Keijdener, M Keil, B Ketzer, Z Khabanova, P Khan, S A Khan, A Khanzadeev, Y Kharlov, A Khatun, A Khuntia, M M Kielbowicz, B Kileng, B Kim, D Kim, D J Kim, H Kim, J S Kim, J Kim, M Kim, S Kim, T Kim, S Kirsch, I Kisel, S Kiselev, A Kisiel, G Kiss, J L Klay, C Klein, J Klein, C Klein-Bösing, S Klewin, A Kluge, M L Knichel, A G Knospe, C Kobdaj, M Kofarago, M K Köhler, T Kollegger, V Kondratiev, N Kondratyeva, E Kondratyuk, A Konevskikh, M Konyushikhin, M Kopcik, M Kour, C Kouzinopoulos, O Kovalenko, V Kovalenko, M Kowalski, G Koyithatta Meethaleveedu, I Králik, A Kravčáková, L Kreis, M Krivda, F Krizek, E Kryshen, M Krzewicki, A M Kubera, V Kučera, C Kuhn, P G Kuijer, A Kumar, J Kumar, L Kumar, S Kumar, S Kundu, P Kurashvili, A Kurepin, A B Kurepin, A Kuryakin, S Kushpil, M J Kweon, Y Kwon, S L La Pointe, P La Rocca, C Lagana Fernandes, Y S Lai, I Lakomov, R Langoy, K Lapidus, C Lara, A Lardeux, A Lattuca, E Laudi, R Lavicka, R Lea, L Leardini, S Lee, F Lehas, S Lehner, J Lehrbach, R C Lemmon, E Leogrande, I León Monzón, P Lévai, X Li, J Lien, R Lietava, B Lim, S Lindal, V Lindenstruth, S W Lindsay, C Lippmann, M A Lisa, V Litichevskyi, W J Llope, D F Lodato, P I Loenne, V Loginov, C Loizides, P Loncar, X Lopez, E López Torres, A Lowe, P Luettig, J R Luhder, M Lunardon, G Luparello, M Lupi, T H Lutz, A Maevskaya, M Mager, S M Mahmood, A Maire, R D Majka, M Malaev, L Malinina, D Mal'Kevich, P Malzacher, A Mamonov, V Manko, F Manso, V Manzari, Y Mao, M Marchisone, J Mareš, G V Margagliotti, A Margotti, J Margutti, A Marín, C Markert, M Marquard, N A Martin, P Martinengo, J A L Martinez, M I Martínez, G Martínez García, M Martinez Pedreira, S Masciocchi, M Masera, A Masoni, E Masson, A Mastroserio, A M Mathis, P F T Matuoka, A Matyja, C Mayer, J Mazer, M Mazzilli, M A Mazzoni, F Meddi, Y Melikyan, A Menchaca-Rocha, E Meninno, J Mercado Pérez, M Meres, S Mhlanga, Y Miake, M M Mieskolainen, D L Mihaylov, K Mikhaylov, A Mischke, A N Mishra, D Miśkowiec, J Mitra, C M Mitu, N Mohammadi, A P Mohanty, B Mohanty, M Mohisin Khan, E Montes, D A Moreira De Godoy, L A P Moreno, S Moretto, A Morreale, A Morsch, V Muccifora, E Mudnic, D Mühlheim, S Muhuri, M Mukherjee, J D Mulligan, M G Munhoz, K Münning, R H Munzer, H Murakami, S Murray, L Musa, J Musinsky, C J Myers, J W Myrcha, D Nag, B Naik, R Nair, B K Nandi, R Nania, E Nappi, A Narayan, M U Naru, H Natal da Luz, C Nattrass, S R Navarro, K Nayak, R Nayak, T K Nayak, S Nazarenko, R A Negrao De Oliveira, L Nellen, S V Nesbo, F Ng, M Nicassio, M Niculescu, J Niedziela, B S Nielsen, S Nikolaev, S Nikulin, V Nikulin, F Noferini, P Nomokonov, G Nooren, J C C Noris, J Norman, A Nyanin, J Nystrand, H Oeschler, A Ohlson, T Okubo, L Olah, J Oleniacz, A C Oliveira Da Silva, M H Oliver, J Onderwaater, C Oppedisano, R Orava, M Oravec, A Ortiz Velasquez, A Oskarsson, J Otwinowski, K Oyama, Y Pachmayer, V Pacik, D Pagano, G Paić, P Palni, J Pan, A K Pandey, S Panebianco, V Papikyan, P Pareek, J Park, S Parmar, A Passfeld, S P Pathak, R N Patra, B Paul, H Pei, T Peitzmann, X Peng, L G Pereira, H Pereira Da Costa, D Peresunko, E Perez Lezama, V Peskov, Y Pestov, V Petráček, V Petrov, M Petrovici, C Petta, R P Pezzi, S Piano, M Pikna, P Pillot, L O D L Pimentel, O Pinazza, L Pinsky, D B Piyarathna, M Płoskoń, M Planinic, F Pliquett, J Pluta, S Pochybova, P L M Podesta-Lerma, M G Poghosyan, B Polichtchouk, N Poljak, W Poonsawat, A Pop, H Poppenborg, S Porteboeuf-Houssais, V Pozdniakov, S K Prasad, R Preghenella, F Prino, C A Pruneau, I Pshenichnov, M Puccio, V Punin, J Putschke, S Raha, S Rajput, J Rak, A Rakotozafindrabe, L Ramello, F Rami, D B Rana, R Raniwala, S Raniwala, S S Räsänen, B T Rascanu, D Rathee, V Ratza, I Ravasenga, K F Read, K Redlich, A Rehman, P Reichelt, F Reidt, X Ren, R Renfordt, A Reshetin, K Reygers, V Riabov, T Richert, M Richter, P Riedler, W Riegler, F Riggi, C Ristea, M Rodríguez Cahuantzi, K Røed, E Rogochaya, D Rohr, D Röhrich, P S Rokita, F Ronchetti, E D Rosas, P Rosnet, A Rossi, A Rotondi, F Roukoutakis, C Roy, P Roy, A J Rubio Montero, O V Rueda, R Rui, B Rumyantsev, A Rustamov, E Ryabinkin, Y Ryabov, A Rybicki, S Saarinen, S Sadhu, S Sadovsky, K Šafařík, S K Saha, B Sahlmuller, B Sahoo, P Sahoo, R Sahoo, S Sahoo, P K Sahu, J Saini, S Sakai, M A Saleh, J Salzwedel, S Sambyal, V Samsonov, A Sandoval, A Sarkar, D Sarkar, N Sarkar, P Sarma, M H P Sas, E Scapparone, F Scarlassara, B Schaefer, H S Scheid, C Schiaua, R Schicker, C Schmidt, H R Schmidt, M O Schmidt, M Schmidt, N V Schmidt, J Schukraft, Y Schutz, K Schwarz, K Schweda, G Scioli, E Scomparin, M Šefčík, J E Seger, Y Sekiguchi, D Sekihata, I Selyuzhenkov, K Senosi, S Senyukov, E Serradilla, P Sett, A Sevcenco, A Shabanov, A Shabetai, R Shahoyan, W Shaikh, A Shangaraev, A Sharma, A Sharma, M Sharma, M Sharma, N Sharma, A I Sheikh, K Shigaki, S Shirinkin, Q Shou, K Shtejer, Y Sibiriak, S Siddhanta, K M Sielewicz, T Siemiarczuk, S Silaeva, D Silvermyr, G Simatovic, G Simonetti, R Singaraju, R Singh, V Singhal, T Sinha, B Sitar, M Sitta, T B Skaali, M Slupecki, N Smirnov, R J M Snellings, T W Snellman, J Song, M Song, F Soramel, S Sorensen, F Sozzi, I Sputowska, J Stachel, I Stan, P Stankus, E Stenlund, D Stocco, M M Storetvedt, P Strmen, A A P Suaide, T Sugitate, C Suire, M Suleymanov, M Suljic, R Sultanov, M Šumbera, S Sumowidagdo, K Suzuki, S Swain, A Szabo, I Szarka, U Tabassam, J Takahashi, G J Tambave, N Tanaka, M Tarhini, M Tariq, M G Tarzila, A Tauro, G Tejeda Muñoz, A Telesca, K Terasaki, C Terrevoli, B Teyssier, D Thakur, S Thakur, D Thomas, F Thoresen, R Tieulent, A Tikhonov, A R Timmins, A Toia, M Toppi, S R Torres, S Tripathy, S Trogolo, G Trombetta, L Tropp, V Trubnikov, W H Trzaska, B A Trzeciak, T Tsuji, A Tumkin, R Turrisi, T S Tveter, K Ullaland, E N Umaka, A Uras, G L Usai, A Utrobicic, M Vala, J Van Der Maarel, J W Van Hoorne, M van Leeuwen, T Vanat, P Vande Vyvre, D Varga, A Vargas, M Vargyas, R Varma, M Vasileiou, A Vasiliev, A Vauthier, O Vázquez Doce, V Vechernin, A M Veen, A Velure, E Vercellin, S Vergara Limón, R Vernet, R Vértesi, L Vickovic, S Vigolo, J Viinikainen, Z Vilakazi, O Villalobos Baillie, A Villatoro Tello, A Vinogradov, L Vinogradov, T Virgili, V Vislavicius, A Vodopyanov, M A Völkl, K Voloshin, S A Voloshin, G Volpe, B von Haller, I Vorobyev, D Voscek, D Vranic, J Vrláková, B Wagner, H Wang, M Wang, D Watanabe, Y Watanabe, M Weber, S G Weber, D F Weiser, S C Wenzel, J P Wessels, U Westerhoff, A M Whitehead, J Wiechula, J Wikne, G Wilk, J Wilkinson, G A Willems, M C S Williams, E Willsher, B Windelband, W E Witt, R Xu, S Yalcin, K Yamakawa, P Yang, S Yano, Z Yin, H Yokoyama, I-K Yoo, J H Yoon, E Yun, V Yurchenko, V Zaccolo, A Zaman, C Zampolli, H J C Zanoli, N Zardoshti, A Zarochentsev, P Závada, N Zaviyalov, H Zbroszczyk, M Zhalov, H Zhang, X Zhang, Y Zhang, C Zhang, Z Zhang, C Zhao, N Zhigareva, D Zhou, Y Zhou, Z Zhou, H Zhu, J Zhu, Y Zhu, A Zichichi, M B Zimmermann, G Zinovjev, J Zmeskal, S Zou
We report a precise measurement of the J/ψ elliptic flow in Pb-Pb collisions at sqrt[s_{NN}]=5.02  TeV with the ALICE detector at the LHC. The J/ψ mesons are reconstructed at midrapidity (|y|<0.9) in the dielectron decay channel and at forward rapidity (2.5<y<4.0) in the dimuon channel, both down to zero transverse momentum. At forward rapidity, the elliptic flow v_{2} of the J/ψ is studied as a function of the transverse momentum and centrality. A positive v_{2} is observed in the transverse momentum range 2<p_{T}<8  GeV/c in the three centrality classes studied and confirms with higher statistics our earlier results at sqrt[s_{NN}]=2...
December 15, 2017: Physical Review Letters
Nikolai V Kolotiniuk, Gerald R Manecke, Michael R Pinsky, Dalia Banks
OBJECTIVE: The primary objective was to compare I-Stat, HemoCue, and RapidLab in measurements of the hemoglobin concentration during cardiac surgeries using cardiopulmonary bypass. DESIGN: Prospective analysis. SETTING: Single-center, academic, tertiary care cardiovascular center. PARTICIPANTS: Thirty-four consecutive patients undergoing cardiac surgery requiring cardiopulmonary bypass. INTERVENTIONS: Blood samples have been collected intraoperatively, and the hemoglobin concentration in each sample was measured, or calculated, simultaneously by the 3 point-of-care devices, HemoCue, RapidLab, and I-Stat...
November 16, 2017: Journal of Cardiothoracic and Vascular Anesthesia
Alana N Pinsky, Kylie Steenbergh, Heather M Boyd, Belen Michael, Delayehu Bekele, Emily Kobernik, Lia Tadesse Gebremedhin, Okeoma Mmeje
OBJECTIVE: To evaluate the acceptability and feasibility of providing assisted reproductive services as part of routine HIV care and treatment in Ethiopia. METHODS: The present cross-sectional study using semistructured in-depth interviews was conducted at St. Paul Hospital Millennium Medical College (SPHMMC), Addis Ababa, Ethiopia, during July 2014 and July 2015. The interviews assessed the perspectives of healthcare providers (HCPs) regarding the reproductive desires of HIV-affected couples, on assisting them in achieving pregnancy, and on the facilitators and barriers to offering such services as part of routine HIV care...
December 15, 2017: International Journal of Gynaecology and Obstetrics
Harry J de Koning, Roman Gulati, Sue M Moss, Jonas Hugosson, Paul F Pinsky, Christine D Berg, Anssi Auvinen, Gerald L Andriole, Monique J Roobol, E David Crawford, Vera Nelen, Maciej Kwiatkowski, Marco Zappa, Marcos Luján, Arnauld Villers, Tiago M de Carvalho, Eric J Feuer, Alex Tsodikov, Angela B Mariotto, Eveline A M Heijnsdijk, Ruth Etzioni
BACKGROUND: The European Randomized Study of Screening for Prostate Cancer (ERSPC) demonstrated that prostate-specific antigen (PSA) screening significantly reduced prostate cancer mortality (rate ratio, 0.79; 95% confidence interval, 0.69-0.91). The US Prostate, Lung, Colorectal, and Ovarian (PLCO) trial indicated no such reduction but had a wide 95% CI (rate ratio for prostate cancer mortality, 1.09; 95% CI, 0.87-1.36). Standard meta-analyses are unable to account for key differences between the trials that can impact the estimated effects of screening and the trials' point estimates...
March 15, 2018: Cancer
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