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https://www.readbyqxmd.com/read/29770769/ct-fluoroscopy-guided-percutaneous-osteoplasty-with-or-without-radiofrequency-ablation-in-the-treatment-of-painful-extraspinal-and-spinal-bone-metastases-technical-outcome-and-complications-in-29-patients
#1
Caroline A Burgard, Julien Dinkel, Frederik Strobl, Philipp M Paprottka, Nicolai Schramm, Maximilian Reiser, Christoph G Trumm
PURPOSE: We aimed to assess the safety and technical outcome of computed tomography (CT) fluoroscopy-guided osteoplasty with or without prior percutaneous radiofrequency ablation (RFA) in patients with painful osteolyses. METHODS: We performed a retrospective analysis of 29 patients with painful extraspinal and spinal osteolyses (16 women, 13 men; 63.1±14.4 years) who underwent CT fluoroscopy-guided osteoplasty (10-20 mAs tube current) with or without RFA (26 and 14 lesions, respectively), in 33 consecutive procedures from 2002 to 2016...
May 2018: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/29769586/increase-in-il-31-serum-levels-is-associated-with-reduced-structural-damage-in-early-axial-spondyloarthritis
#2
Nicolas Rosine, Adrien Etcheto, Houria Hendel-Chavez, Raphaèle Seror, Karine Briot, Anna Molto, Philippe Chanson, Yassine Taoufik, Daniel Wendling, Rik Lories, Francis Berenbaum, Rosaline van den Berg, Pascal Claudepierre, Antoine Feydy, Maxime Dougados, Christian Roux, Corinne Miceli-Richard
In spondyloarthritis, little is known about the relation between circulating cytokines and patient phenotype. We have quantified serum levels of T helper type 1 cell (Th1), Th2 and Th17 cytokines in patients with recent-onset axial spondyloarthritis (AxSpA) from the DESIR cohort, a prospective, multicenter French cohort consisting of 708 patients with recent-onset inflammatory back pain (duration >3 months but <3 years) suggestive of AxSpA. Serum levels of Th1, Th2, and Th17 cytokines were assessed at baseline in patients from the DESIR cohort fulfilling the ASAS criteria (ASAS+) and were compared with age- and sex-matched healthy controls...
May 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29764822/numb-chin-syndrome-an-ominous-sign-of-mandibular-metastasis
#3
Abdul Razak, Bee See Goh, Jothi Raamahlingam Rajaran, Abd Jabar Nazimi
A 51-year-old woman a known case of stage 2 breast carcinoma in 2006 and underwent left mastectomy performed in the same year presented with bilateral lower limb pain suggestive of spinal pathology, and left chin numbness, both of 2 weeks' duration. Examination revealed left mandibular hypoesthesia without any other sign or symptoms. Orthopantomogram was unremarkable apart from mild alveolar bone expansion at tooth 36 area, which was extracted 3 months earlier. Subsequently, a full-body positron emission tomography contrast enhanced computer tomography revealed hypermetabolic lesions of her axial (excluding skull) and appendicular skeleton...
May 14, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29748070/morphometric-tibial-implant-decreases-posterior-overhang-rate-and-improves-clinical-outcomes-results-of-a-prospective-matched-controlled-study
#4
Paul Bizzozero, Yassine Bulaid, Xavier Flecher, Matthieu Ollivier, Sébastien Parratte, Jean-Noel Argenson
BACKGROUND: Tibial implant's positioning in total knee arthroplasty (TKA) requires a compromise between implant's rotation and bone coverage. We hypothesized that morphometric tibial trays (MTTs) would improve implant positioning and clinical outcomes as compared with symmetrical tibial trays. METHODS: Thirty-three patients were included prospectively according to the following criteria: age from 18 to 85 years, body mass index <35 kg/m2 , and posterostabilized cemented TKA performed for primary arthritis...
April 19, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29745883/prevalence-and-characteristics-associated-with-dactylitis-in-patients-with-early-spondyloarthritis-results-from-the-esperanza-cohort
#5
Maria Isabel Tévar-Sánchez, Victoria Navarro-Compán, Juan J Aznar, Luis F Linares, Maria C Castro, Eugenio De Miguel
OBJECTIVES: Dactylitis is a typical feature of psoriatic arthritis. However, dactylitis was included as a spondyloarthritis (SpA) feature for both (axial and peripheral) of the ASAS classification criteria, but data about its prevalence are scarce, especially in patients with a recent onset of the disease. Our objective was to determine the prevalence and characteristics associated with dactylitis in patients with early SpA. METHODS: A baseline dataset from the ESPeranza cohort was used...
May 8, 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29737732/-clinical-analysis-of-arytenoid-cartilage-reposition-with-snake-mouth-forceps-for-the-arytenoid-cartilage-dislocation
#6
Qing Xiang Zhang, Shuang Ba He, Zi Gang Che, Hui Ying Hu, Ya Qun Liu, Yuan Yuan Lu, Zhen Kun Yu
OBJECTIVES: To investigate the clinical effect of the arytenoid cartilage reposition using snake mouth reduction forceps under general anesthesia. METHODS: Data of twenty-six cases accepted arytenoid cartilage reposition under intravenous general anesthesia were analyzed, nineteen cases accepted laryngeal CT scan and cricoarytenoid joint reconstruction, all patients underwent endolaryngeal muscle electromyography examination. According to the position of cartilage dislocation prompted by laryngoscope and CT, the arytenoid cartilage was repositoned under the visual laryngoscope using special snake mouth reduction forceps...
March 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29734942/methodological-considerations-in-region-of-interest-definitions-for-paraspinal-muscles-in-axial-mris-of-the-lumbar-spine
#7
David B Berry, Jennifer Padwal, Seth Johnson, Callan L Parra, Samuel R Ward, Bahar Shahidi
BACKGROUND: Magnetic Resonance Imaging (MRI) is commonly used to assess the health of the lumbar spine and supporting structures. Studies have suggested that fatty infiltration of the posterior lumbar muscles is important in predicting responses to treatment for low back pain. However, methodological differences exist in defining the region of interest (ROI) of a muscle, which limits the ability to compare data between studies. The purpose of this study was to determine reliability and systematic differences within and between two commonly utilized methodologies for ROI definitions of lumbar paraspinal muscle...
May 7, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29725538/appendiceal-carcinoma-associated-with-microsatellite-instability
#8
Angélica Morales-Miranda, Ismael Domínguez Rosado, Carlos Chan Núñez, Fredy Chable Montero
Approximately 15% of colorectal cancer (CRC) cases exhibit microsatellite instability (MSI), which appears to be associated with unique biological behavior. The present study presents a case of appendiceal carcinoma associated with MSI that responded well to adjuvant chemotherapy. Clinical, pathological and immunohistochemical (IHC) characteristics have been described. The 60-year-old male patient had suffered from recurrent lower abdominal pain associated with abdominal distention for 6 months; then, following an acute attack, he was subjected to laparoscopic appendectomy...
May 2018: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29717103/angina-pectoris-in-young-male-due-to-agenesis-of-left-circumflex-artery
#9
Thomas J Guterbaum, Kristian A Øvrehus, Karsten T Veien, Jacob E Møller, Hans Mickley
BACKGROUND This case study demonstrated that although highly symptomatic, agenesis of the left circumflex artery was a benign finding. Anomalies of the coronary arteries were found to be the cause of sudden death in a young individual. Left circumflex anomalies were not associated with major cardiac events. CASE REPORT A 20-year-old male was admitted due to syncope preceded by chest pain. His electrocardiogram (ECG) showed global ST segment elevation as well as biphasic T waves in anterior precordial leads...
May 2, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29715707/rib-radiography-versus-chest-computed-tomography-in-the-diagnosis-of-rib-fractures
#10
Atsushi Sano
BACKGROUND:  The accurate diagnosis of rib fractures is important in chest trauma. Diagnostic images following chest trauma are usually obtained via chest X-ray, chest computed tomography, or rib radiography. This study evaluated the diagnostic characteristics of rib radiography and chest computed tomography. METHODS:  Seventy-five rib fracture patients who underwent both chest computed tomography and rib radiography between April 2008 and December 2013 were included...
May 1, 2018: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/29710666/cytotoxic-analgesic-and-anti-inflammatory-properties-of-syzygium-calophyllifolium-bark
#11
Rahul Chandran, Heidi Abrahamse, Thangaraj Parimelazhagan
The present study explores the effect of Syzygium calophyllifolium bark methanol (SCBM) extract on pain and inflammation as cancer associated symptoms. The anti-proliferative and cell death-inducing ability of the extract was analysed using MCF-7 breast cancer cells. ATP and LDH levels, along with the cell morphology were noted. The anti-proliferative ability of the extract was examined in relation to pain and inflammation. Analgesic activity was determined using a hot plate, acetic acid and formalin-induced pain models in mice...
April 25, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29708517/neuropathic-pain-component-in-axial-spondyloarthritis-and-the-influence-on-disease-burden
#12
Kevser Gok, Gizem Cengiz, Kemal Erol, Salih Ozgocmen
OBJECTIVES: Patients with nonradiographic axial spondyloarthritis (nr-axSpA) and radiographic axSpA/ankylosing spondylitis (AS) have similar burden of disease; however, the potential influence of pain characteristics including the neuropathic pain (NeP) component has not been assessed yet. The aim of this study was first to assess frequency of NeP component in patients with axSpA and second to assess the potential influence of NeP on burden of disease. METHODS: Adult patients who met the Assessment of SpondyloArthritis International Society classification criteria for axSpA were consecutively recruited...
February 22, 2018: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/29706731/percutaneous-intramedullary-headless-screw-fixation-and-wide-awake-anesthesia-to-treat-metacarpal-fractures-early-results-in-25-patients
#13
Andrea Poggetti, Anna Maria Nucci, Thomas Giesen, Maurizio Calcagni, Stefano Marchetti, Michele Lisanti
Metacarpal fractures constitute 7.8% of the upper extremity fractures. The common treatments remain nonsurgical procedure, but high-demanding patients or unstable fractures require fixation with Kirschner wire (K-wires), plate, and screws. However, these approaches may cause scarring and adhesion with poor functional results. From 2014 to 2015, the authors used an intramedullary headless screw to treat 25 patients (24 men, 1 woman) with metacarpal bones fractures (20 V, 3 IV, 1 III, and 1 II). The fractures patterns were 23 fractures of distal third of metacarpal bone (16 oblique, 5 comminute configurations, and 2 transverse), 1 fracture of the base of the II metacarpal bone...
April 2018: Journal of Hand and Microsurgery
https://www.readbyqxmd.com/read/29705167/stiff-person-syndrome-with-evidence-of-non-specific-focal-myositis-secondary-to-sustained-muscle-contraction-a-case-report
#14
Seung-Wook No, Il-Gyu Lim, Du Hwan Kim
Stiff person syndrome (SPS) is a rare neuroimmunological disorder characterized by progressive muscular rigidity and spasms that affect axial and limb muscles. There have been a few reports that patients with SPS had evidences of polymyositis (PM). There have been no clear explanations about the characteristics of PM in SPS. We report the case of a 36-year-old woman with SPS in association with non-specific focal myositis secondary to sustained muscle contraction. She presented with stiffness and pain in her extremities, and diazepam and baclofen were ineffective...
April 26, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29681630/guidelines-on-the-application-of-the-clinical-practice-guideline-on-low-back-pain
#15
José María Jiménez-Ávila, Erik Noe Rubio-Flores, Arelhi Catalina González-Cisneros, Jaime Eduardo Guzmán-Pantoja, Elsa Armida Gutiérrez-Román
Introduction: Low back pain is defined as pain in the upper portion of T12 and below the crease of the buttocks and functional limitation. The prevalence of low back pain gradually increases 11.4% per year. In Mexico, the clinical practice guidelines are not followed in handling low back pain, so it is important to systematize medical care more efficient, since resources are scarce. The first level doctor must meet the benchmarks according to patient need, an incomplete anamnesis is performed, inadequate physical examination, misinterpretation of clinical studies, misdiagnosis, ineffective management, and reference to second or third level not justified...
2018: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/29681195/biologics-for-treating-axial-spondyloarthritis
#16
Alexis Jones, Coziana Ciurtin, Mediola Ismajli, Maria Leandro, Raj Sengupta, Pedro M Machado
Spondyloarthritis (SpA) encompasses a heterogeneous group of diseases sharing genetic, immunological, clinical and imaging features. Axial spondyloarthritis (axSpA) refers to a subgroup characterised predominately by inflammation of the axial skeleton with subsequent symptoms of chronic (often inflammatory) back pain and sacroiliitis. There is a strong association with the major histocompatibility complex (MHC) class I allele human leukocyte antigen (HLA) B27. In the last decade, there has been significant progress in earlier detection of the disease and the molecular mechanisms involved in its pathogenesis...
April 21, 2018: Expert Opinion on Biological Therapy
https://www.readbyqxmd.com/read/29678187/an-unexpected-cause-of-sacroiliitis-in-a-patient-with-gout-and-chronic-psoriasis-with-inflammatory-arthritis-a-case-report
#17
Safi Alqatari, Roberta Visevic, Nina Marshall, John Ryan, Grainne Murphy
BACKGROUND: Inflammatory back pain is a condition characterized by inflammation of the sacroiliac joints and lower spine. It is frequently seen in patients with spondyloarthropathies like ankylosing spondylitis, psoriatic arthritis, enteropathic arthritis and reactive arthritis. Inflammatory back pain can be caused by many other conditions like infection and crystal deposition such as gout. In this case, it is difficult to specifically identify gout as a cause by ordinary imaging like magnetic resonance imaging (MRI) or ultrasound...
April 20, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29673341/runners-with-patellofemoral-pain-demonstrate-sub-groups-of-pelvic-acceleration-profiles-using-hierarchical-cluster-analysis-an-exploratory-cross-sectional-study
#18
Ricky Watari, Sean T Osis, Angkoon Phinyomark, Reed Ferber
BACKGROUND: Previous studies have suggested that distinct and homogenous sub-groups of gait patterns exist among runners with patellofemoral pain (PFP), based on gait analysis. However, acquisition of 3D kinematic data using optical systems is time consuming and prone to marker placement errors. In contrast, axial segment acceleration data can represent an overall running pattern, being easy to acquire and not influenced by marker placement error. Therefore, the purpose of this study was to determine if pelvic acceleration patterns during running could be used to classify PFP patients into homogeneous sub-groups...
April 19, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29669689/3-dimensional-cervical-movement-characteristics-and-the-influence-of-thoracic-treatment-on-a-subgroup-of-acute-neck-pain-patients
#19
Nikolas L Krott, Gunnar M Bloyinski, Erik Cattrysse
OBJECTIVE: The purpose of this study was to investigate the influence of thoracic high-velocity low-amplitude thrust (HVLAT) manipulation on quantitative and qualitative 3-dimensional cervical spine kinematic patterns in a subgroup of patients with acute neck pain. METHODS: Thirty patients with acute neck pain, aged 20 to 59, received a thoracic HVLAT manipulation. Three-dimensional kinematics of the cervical spine were registered pretreatment and posttreatment using an electromagnetic tracking system...
April 15, 2018: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/29665824/inflammatory-back-pain-in-psoriatic-arthritis-is-significantly-more-responsive-to-corticosteroids-compared-to-back-pain-in-ankylosing-spondylitis-a-prospective-open-labelled-controlled-pilot-study
#20
Muhammad Haroon, Muddassar Ahmad, Muhammad Nouman Baig, Olivia Mason, John Rice, Oliver FitzGerald
BACKGROUND: The efficacy of corticosteroids in patients with psoriatic arthritis (PsA) and inflammatory back pain has not been studied to date. In this controlled trial, we aimed to investigate the comparative performance of corticosteroids in patients with active axial-PsA (AxPsA) versus those with active ankylosing spondylitis (AS). METHODS: Patients with AxPsA and AS (naïve to biologic therapies), who not only had clinically active disease, but also had bone marrow oedema on magnetic resonance imaging of the sacroiliac joints, were recruited...
April 17, 2018: Arthritis Research & Therapy
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