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spondylotic myelopathy

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https://www.readbyqxmd.com/read/28711563/application-of-neurite-orientation-dispersion-and-density-imaging-or-diffusion-tensor-imaging-to-quantify-the-severity-of-cervical-spondylotic-myelopathy-and-assess-postoperative-neurological-recovery
#1
Genki Okita, Tetsuro Ohba, Tomohiro Takamura, Shigeto Ebata, Ryo Ueda, Hiroshi Onishi, Hirotaka Haro, Masaaki Hori
BACKGROUND CONTEXT: Surgical outcome and the severity of cervical spondylotic myelopathy (CSM) are unpredictable and cannot be estimated by conventional anatomical MRI. The utility of diffusion tensor imaging (DTI) to quantify the severity of CSM and assess postoperative neurological recovery has been investigated. However, whether conventional DTI should be applied in a clinical setting remains controversial. Neurite orientation dispersion and density imaging (NODDI) is a recently introduced model-based diffusion-weighted MRI technique that quantifies specific microstructural features related directly to neuronal morphology...
July 12, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28708041/microendoscopic-laminotomy-versus-conventional-laminoplasty-for-cervical-spondylotic-myelopathy-5-year-follow-up-study
#2
Akihito Minamide, Munehito Yoshida, Andrew K Simpson, Hiroshi Yamada, Hiroshi Hashizume, Yukihiro Nakagawa, Hiroshi Iwasaki, Shunji Tsutsui, Motohiro Okada, Masanari Takami, Shin-Ichi Nakao
OBJECTIVE The goal of this study was to characterize the long-term clinical and radiological results of articular segmental decompression surgery using endoscopy (cervical microendoscopic laminotomy [CMEL]) for cervical spondylotic myelopathy (CSM) and to compare outcomes to conventional expansive laminoplasty (ELAP). METHODS Consecutive patients with CSM who required surgical treatment were enrolled. All enrolled patients (n = 78) underwent CMEL or ELAP. All patients were followed postoperatively for more than 5 years...
July 14, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28704622/assessment-of-psychometric-properties-of-various-balance-assessment-tools-in-persons-with-cervical-spondylotic-myelopathy
#3
Alice Y Y Chiu, Marco Y C Pang
Study Design Clinical measurement; cross-sectional, repeated measures. Background Persons with cervical spondylotic myelopathy (CSM) are known to have balance impairments. The psychometric properties of various balance assessment tools have not been evaluated in this population. Objective To examine the floor and ceiling effects, item difficulty and item discrimination index, internal consistency, reliability, and validity of the Balance Evaluation Systems Test (BESTest), Mini-BESTest, Brief-BESTest and Berg balance scale (BBS) in persons with CSM...
July 13, 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28704332/the-image-diagnostic-classification-of-mr-t2-increased-signal-intensity-in-cervical-spondylotic-myelopathy-clinical-evaluation-using-quantitative-and-objective-assessment
#4
Masaaki Machino, Shiro Imagama, Kei Ando, Kazuyoshi Kobayashi, Kenyu Ito, Mikito Tsushima, Akiyuki Matsumoto, Masayoshi Morozumi, Satoshi Tanaka, Keigo Ito, Fumihiko Kato, Yoshihiro Nishida, Naoki Ishiguro
STUDY DESIGN: A prospective imaging study OBJECTIVE.: The study investigated whether the classification of increased signal intensity (ISI) using magnetic resonance imaging (MRI) reflects the severity of symptoms in patients with cervical spondylotic myelopathy (CSM). SUMMARY OF BACKGROUND DATA: Although the ISI on MRI in patients with CSM is observed, the degree of ISI has not been examined. The association between ISI and the surgical outcomes in cervical myelopathy remains controversial...
July 12, 2017: Spine
https://www.readbyqxmd.com/read/28703331/high-resolution-diffusion-tensor-imaging-in-cervical-spondylotic-myelopathy-a-preliminary-follow-up-study
#5
Li Guan, Xiaolong Chen, Yong Hai, Xiaodong Ma, Le He, Guangzhi Wang, Chun Yuan, Hua Guo
Diffusion imaging is a promising technique as it can provide microstructural tissue information and thus potentially show viable changes in spinal cord. However, the traditional single-shot imaging method is limited as a result of various image artifacts. In order to improve measurement accuracy, we used a newly developed, multi-shot, high-resolution, diffusion tensor imaging (DTI) method to investigate diffusion metric changes and compare them with T2 -weighted (T2W) images before and after decompressive surgery for cervical spondylotic myelopathy (CSM)...
July 13, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28701500/assessing-structure-and-function-of-myelin-in-cervical-spondylotic-myelopathy-evidence-of-demyelination
#6
Hanwen Liu, Erin L MacMillian, Catherine R Jutzeler, Emil Ljungberg, Alex L MacKay, Shannon H Kolind, Burkhard M├Ądler, David K B Li, Marcel F Dvorak, Armin Curt, Cornelia Laule, John L K Kramer
PURPOSE: To assess the extent of demyelination in cervical spondylotic myelopathy (CSM) using myelin water imaging (MWI) and electrophysiologic techniques. METHODS: Somatosensory evoked potentials (SSEPs) and MWI were acquired in 14 patients with CSM and 18 age-matched healthy controls. MWI was performed on a 3.0T whole body magnetic resonance scanner. Myelin water fraction (MWF) was extracted for the dorsal columns and whole cord. SSEPs and MWF were also compared with conventional MRI outcomes, including T2 signal intensity, compression ratio, maximum spinal cord compression (MSCC), and maximum canal compromise (MCC)...
July 12, 2017: Neurology
https://www.readbyqxmd.com/read/28692908/surgical-outcomes-of-laminoplasty-for-cervical-spondylotic-myelopathy-in-very-elderly-patients-older-than-80-years-time-from-symptom-onset-to-surgery-and-changes-in-spinal-cord-signal-intensity-on-mri
#7
Naoki Notani, Masashi Miyazaki, Shozo Kanezaki, Toshinobu Ishihara, Hiroshi Tsumura
OBJECTIVE: We aimed to assess the surgical outcomes of laminoplasty for cervical spondylotic myelopathy (CSM) in very elderly patients (older than 80 years), focusing specifically on the time from symptom onset to surgery and on the loss in spinal cord signal intensity on magnetic resonance imaging (MRI). PATIENTS AND METHODS: We retrospectively reviewed 100 consecutive patients (61 males and 39 females) with CSM who underwent laminoplasty between 2006 and 2014...
July 1, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28690192/suppression-of-osteogenic-differentiation-in-mesenchymal-stem-cells-from-patients-with-ossification-of-the-posterior-longitudinal-ligament-by-a-histamine-2-receptor-antagonist
#8
Xizhe Liu, Gentaro Kumagai, Kanichiro Wada, Toshihiro Tanaka, Taku Fujita, Ayako Sasaki, Ken-Ichi Furukawa, Yasuyuki Ishibashi
Mesenchymal stem cells (MSCs) in ossification of the posterior longitudinal ligament (OPLL) patients have a high propensity toward osteogenesis. Histamine receptor H2 (H2R) antagonists (H2 blockers) like famotidine decrease ossification in patients, by an unclear mechanism. To confirm that MSCs express H2R and to clarify how H2 blockers suppress osteogenic differentiation, we used spinal-ligament MSCs from patients with OPLL or with cervical spondylotic myelopathy (CSM) (control). The MSCs were treated with 10, 30, or 100nM famotidine for 7 or 21 days...
July 8, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28678119/risk-factors-for-and-clinical-outcomes-of-dysphagia-after-anterior-cervical-surgery-for-degenerative-cervical-myelopathy-results-from-the-aospine-international-and-north-america-studies
#9
Narihito Nagoshi, Lindsay Tetreault, Hiroaki Nakashima, Paul M Arnold, Giuseppe Barbagallo, Branko Kopjar, Michael G Fehlings
BACKGROUND: Although dysphagia is a common complication after anterior cervical decompression and fusion, important risk factors have not been rigorously evaluated. Furthermore, the impact of dysphagia on neurological and quality-of-life outcomes is not fully understood. The aim of this study was to determine the prevalence of and risk factors for dysphagia, and the impact of this complication on short and long-term clinical outcomes, in patients treated with anterior cervical decompression and fusion...
July 5, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28676461/cervical-burst-fracture-in-a-patient-with-contiguous-two-level-cervical-stand-alone-cages-a-case-report
#10
Rui Feng, Joshua Loewenstern, John Caridi
BACKGROUND: Cervical stand-alone interbody cages have seen increasingly wider use over the plate-and-screw construct in single-level anterior cervical discectomy and fusion (ACDF) in the treatment of cervical disc herniation and degenerative spondylotic conditions. Despite positive clinical outcomes, the efficacy and safety of using these devices in contiguous multi-level ACDF, however, has remained controversial. CASE DESCRIPTION: This report discusses a burst fracture seen as a complication in multi-level cervical stand-alone cage use...
July 1, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28673888/two-year-results-of-the-prospective-spine-treatment-outcomes-study-an-analysis-of-complication-rates-predictors-of-their-development-and-effect-on-patient-derived-outcomes-at-2-years-for-surgical-management-of-cervical-spondylotic-myelopathy
#11
Michael C Gerling, Peter Passias, Kris Radcliff, Robert Isaacs, Kristina Bianco, Cyrus M Jalai, Nancy J Worley, Jaspreet Parmar, Gregory W Poorman, Samantha R Horn, John Y Moon, Paul M Arnold, Alexander R Vaccaro
No abstract text is available yet for this article.
June 30, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28670421/response-to-does-segmental-kyphosis-affect-surgical-outcome-after-a-posterior-decompressive-laminectomy-in-multisegmental-cervical-spondylotic-myelopathy
#12
Akshay Jain, Tarush Rustagi, Gautam Prasad, Tushar Deore, Shekhar Y Bhojraj
No abstract text is available yet for this article.
June 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/28670420/letter-to-the-editor-does-segmental-kyphosis-affect-surgical-outcome-after-a-posterior-decompressive-laminectomy-in-multisegmental-cervical-spondylotic-myelopathy
#13
COMMENT
Vibhu Krishnan Viswanathan, Surabhi Subramanian
No abstract text is available yet for this article.
June 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/28647748/single-level-anterior-cervical-corpectomy-and-fusion-using-a-new-3d-printed-anatomy-adaptive-titanium-mesh-cage-for-treatment-of-cervical-spondylotic-myelopathy-and-ossification-of-the-posterior-longitudinal-ligament-a-retrospective-case-series-study
#14
Teng Lu, Chao Liu, Baohui Yang, Jiantao Liu, Feng Zhang, Dong Wang, Haopeng Li, Xijing He
BACKGROUND The aim of this study was to evaluate the clinical and radiological outcomes of the use of a new 3D-printed anatomy-adaptive titanium mesh cage (AA-TMC) for single-level anterior cervical corpectomy and fusion (ACCF) in patients with cervical spondylotic myelopathy (CSM) and ossification of the posterior longitudinal ligament (OPLL). MATERIAL AND METHODS We retrospectively reviewed the records of 15 consecutive patients who underwent ACCF surgeries with AA-TMC implantation. The Japanese Orthopedic Association (JOA) scoring system, a visual analogue scale (VAS), the mean intervertebral height (MIBH) of the surgical segments, and the surgical segmental angle (SSA) were recorded preoperatively, immediately after surgery and at the final follow-up visit...
June 25, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28625909/multilevel-acdf-with-zero-profile-devices-analysis-of-safety-and-feasibility-with-a-focus-on-sagittal-alignment-and-its-impact-on-clinical-outcome-a-single-institution-experience-and-review-of-the-literature
#15
Vincenzo Albanese, Francesco Certo, Massimiliano Visocchi, Giuseppe Mv Barbagallo
BACKGROUND: In multilevel degenerative conditions posterior approaches are often preferred, but anterior approaches provide comparable clinical results and better alignment. Anterior plating entails higher rates of soft tissue injuries and dysphagia, particularly in multilevel cases. This study evaluates efficacy and safety of zero-profile devices in three and four-level ACDF, analyzing patients' clinical and radiological long-term outcome. METHODS: We prospectively enrolled 24 patients with cervical spondylotic myeloradiculopathy (CSM), who underwent three and four-level ACDF with Zero-P device...
June 15, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28619491/the-accuracy-of-multimodality-intraoperative-neuromonitoring-to-predict-postoperative-neurological-deficits-following-cervical-laminoplasty
#16
Junichi Oya, John F Burke, Todd Vogel, Boby Tay, Dean Chou, Praveen Mummaneni
BACKGROUND: Intraoperative neuromonitoring (IONM) has been reported to be sensitive and specific in the detection of neurological injury during spinal surgery. However, utilizing multimodality IONM to predict postoperative neural deficits following cervical laminoplasty remains unclear. OBJECTIVE: The purpose of this study is to clarify the incidence of C5 palsy utilizing multimodality IONM and to compare the accuracy of multimodality IONM to predict postoperative C5 palsy against isolated transcranial motor-evoked potential (MEP)...
June 12, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28607826/socioeconomic-and-regional-differences-in-the-treatment-of-cervical-spondylotic-myelopathy
#17
Sheri K Palejwala, Anand I Rughani, G Michael Lemole, Travis M Dumont
BACKGROUND: Cervical spondylotic myelopathy (CSM) is the leading cause of spinal cord dysfunction in the world. Surgical treatment is both medically and economically advantageous, and can be achieved through multiple approaches, with or without fusion. We used the Nationwide Inpatient Sample (NIS) database to better elucidate regional and socioeconomic variances in the treatment of CSM. METHODS: The NIS database was queried for elective admissions with a primary diagnosis of CSM (ICD-9 721...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28606250/-three-dimensional-finite-element-model-of-a-modified-posterior-cervical-single-open-door-laminoplasty
#18
Q Wang, Y Yang, Q Fei, D Li, J J Li, H Meng, N Su, Z H Fan, B Q Wang
Objective: To build a three-dimensional finite element models of a modified posterior cervical single open-door laminoplasty with short-segmental lateral mass screws fusion. Methods: The C(2)-C(7) segmental data were obtained from computed tomography (CT) scans of a male patient with cervical spondylotic myelopathy and spinal stenosis.Three-dimensional finite element models of a modified cervical single open-door laminoplasty (before and after surgery) were constructed by the combination of software package MIMICS, Geomagic and ABAQUS...
June 6, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28594510/surgical-management-of-cervical-spondylotic-myelopathy
#19
Chris A Cornett, James D Kang, Joon Yung Lee, Clinton James Devin, Emmett Gannon, Elliott Kim, Sean M Esmende
Cervical spondylotic myelopathy (CSM) is a common cause of neurologic impairment in adults worldwide. Numerous studies have investigated the pathophysiology of CSM, which has provided surgeons with insight on the important factors that lead to the symptoms and deficits observed in patients who have CSM. However, further analysis of many unknown aspects of CSM is required to fully understand the disease and potential alternative treatment modalities. The diagnosis of CSM is based on a patient's history and physical examination and then confirmed with imaging studies...
February 15, 2017: Instructional Course Lectures
https://www.readbyqxmd.com/read/28591038/indication-for-hypertrophy-posterior-longitudinal-ligament-removal-in-anterior-decompression-for-cervical-spondylotic-myelopathy
#20
Chengrui Bai, Kanghua Li, Ai Guo, Qi Fei, Dong Li, Jinjun Li, Bingqiang Wang, Yong Yang
The retrospective study aimed to investigate the indication for hypertrophy posterior longitudinal ligament (HPLL) removal in anterior decompression for cervical spondylotic myelopathy (CSM). A total of 138 consecutive patients with CSM were divided into 2 groups with developmental cervical stenosis (DCS) (group S) and non-DCS (group N), according to the Pavlov ratio. These 2 groups were subdivided into 2 further subgroups, according to whether HPLL was removed or preserved: group SR (49 patients) and group SP (32 patients) in group S, group NR (21 patients) and group NP (36 patients) in group N...
June 2017: Medicine (Baltimore)
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