keyword
MENU ▼
Read by QxMD icon Read
search

spondylotic myelopathy

keyword
https://www.readbyqxmd.com/read/28809390/clinical-features-and-surgical-outcomes-of-cervical-spondylotic-myelopathy-in-patients-of-different-ages-a-retrospective-study
#1
R J Zhang, C L Shen, J X Zhang, X J Zhang, F L Dong, H Tao, P W Song, P Ge, P Xu, H Q Zhang
STUDY DESIGN: Retrospective chart audit. OBJECTIVES: This study aims to compare the clinical features and surgical outcomes in patients with cervical spondylotic myelopathy (CSM) among different age groups. SETTING: The first Affiliated Hospital of Anhui Medical University, China. METHODS: A total of 460 patients with CSM who were surgically treated over the period of 1995-2009 were investigated. Considering the peak age (40-60 years old) for the onset of symptoms, we divided the patients into three groups by age: young (<40), middle-aged (40-60), and old (>60)...
August 15, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28790004/cervical-paraspinal-muscle-atrophy-rates-following-laminoplasty-and-laminectomy-with-fusion-for-cervical-spondylotic-myelopathy
#2
Adedayo O Ashana, Remi M Ajiboye, William L Sheppard, Akshay Sharma, Andrew B Kay, Langston T Holly
BACKGROUND: Cervical spondylotic myelopathy (CSM) is a disorder that can cause neurologic deterioration. Studies on paraspinal muscular atrophy (PMA) in the lumbar spine have shown these changes are caused by several perioperative factors. It is possible that PMA in the cervical spine could behave similarly. In this retrospective study, we compared the degree of PMA after laminoplasty versus laminectomy and fusion (LF) using a standard posterior approach to the cervical spine. METHODS: 18 laminoplasty and 43 LF patients were included in this study...
August 5, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28765801/regression-of-disc-osteophyte-complexes-following-laminoplasty-versus-laminectomy-with-fusion-for-cervical-spondylotic-myelopathy
#3
Remi M Ajiboye, Stephen D Zoller, Adedayo A Ashana, Akshay Sharma, William Sheppard, Langston T Holly
BACKGROUND: Laminectomy with fusion (LF) and laminoplasty are two posterior-based surgical approaches for the surgical treatment of cervical spondylotic myelopathy (CSM). The decompressive effect of these approaches is thought to be primarily related to the dorsal drift of the spinal cord away from ventral compressive structures. A lesser known mechanism of spinal cord decompression following cervical LF is regression of the ventral disc osteophyte complexes which is postulated to result from the alteration of motion across the fused motion segment...
2017: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/28765794/diabetes-as-an-independent-predictor-for-extended-length-of-hospital-stay-and-increased-adverse-post-operative-events-in-patients-treated-surgically-for-cervical-spondylotic-myelopathy
#4
Nancy Worley, John Buza, Cyrus M Jalai, Gregory W Poorman, Louis M Day, Shaleen Vira, Shearwood McClelland Iii, Virginie Lafage, Peter G Passias
BACKGROUND: Diabetes as an independent driver of peri-operative outcomes, and whether its severity impacts indications is conflicted in the research. The purpose of this study is to evaluate diabetes as a predictor for postoperative outcomes in cervical spondylotic myelopathy (CSM) patients. METHODS: A retrospective review was performed of patients treated surgically for CSM (ICD-9 721.1) from 2010-2012 in the prospectively-collected American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database...
2017: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/28761535/prognostication-in-cervical-spondylotic-myelopathy-proposal-for-a-new-simple-practical-scoring-system
#5
Vengalathur Ganesan Ramesh, Manianandan Ganapathi Vel Kannan, Kuchalmbal Sriram, Chandramouli Balasubramanian
CONTEXT: The ability to preoperatively predict the outcome in cervical spondylotic myelopathy (CSM) helps in planning management and counseling the patient and family. AIMS: A simple prognostic scale, namely, the Madras Institute of Neurology Prognostic Scale (MINPS) for CSM has been proposed. SETTINGS AND DESIGN: Six well-known prognostic factors, namely, age, duration of symptoms, neurological disability (Nurick's grade), number of levels of compression, effective canal diameter, and intrinsic cord changes, have been taken into account...
July 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28756456/clinical-predictors-of-surgical-outcomes-and-imaging-features-in-single-segmental-cervical-spondylotic-myelopathy-with-lower-cervical-instability
#6
Kuan Lu, Xianda Gao, Tong Tong, Dechao Miao, Wenyuan Ding, Yong Shen
BACKGROUND Cervical degenerative changes are the most common cause of cervical spondylotic myelopathy (CSM) and lower cervical instability (LCI). The purpose of this study was to investigate the associated factors of MRI signal changes and prognosis in single segmental CSM accompanied by LCI. MATERIAL AND METHODS A total of 122 patients met the inclusion criteria and were enrolled in this study with a minimum follow-up period of 2 years. According to the absence/presence of LCI, patients were divided into the unstable group (n=43 [35...
July 30, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28746221/diagnosis-and-treatment-of-hidden-lesions-in-mild-cervical-spondylotic-myelopathy-patients-with-apparent-symptoms
#7
Yaning Sun, Kunlun Yu, Haonan Wang, Yong Shen, Lingde Kong, Jingtao Zhang
Patients with apparent symptoms of cervical spondylotic myelopathy (CSM) may only show a mild compressive lesion in ordinary magnetic resonance imaging (MRI). The aim of this study was to investigate the characteristics of CSM patients with "hidden" lesions on kinetic MRI and to determine an effective treatment.Thirty-one patients with obvious spinal cord compression only on kinetic MRI were included in our study. A variety of parameters were calculated from MRI of the cervical spine at different postures. The anterior cervical decompression and fusion (ACDF) procedure were used for treatment of CSM...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28742760/a-randomized-trial-comparing-clinical-outcomes-between-zero-profile-and-traditional-multi-level-anterior-cervical-discectomy-and-fusion-surgery-for-cervical-myelopathy
#8
Shenghua He, Hualong Feng, Zhiming Lan, Lai Juyi, Zhitao Sun, Yeguang Wang, Jian Wang, Zhiqiang Ren, Feiqiang Huang, Fuguang Xu
STUDY DESIGN: Prospective randomized study from a single center OBJECTIVE.: The purpose of this study was to compare outcomes between a zero-profile (ZP) anterior cervical discectomy and fusion (ACDF) construct to a traditional ACDF with anterior plate (ACP) in the treatment of multilevel cervical spondylotic myelopathy. SUMMARY OF BACKGROUND DATA: Multi-level cervical spondylotic myelopathy can be treated by a variety of techniques, most commonly with corpectomy, ACDF, posterior cervical fusion or a combination of the three...
July 24, 2017: Spine
https://www.readbyqxmd.com/read/28734792/genetic-factors-of-cervical-spondylotic-myelopathy-a-systemic-review
#9
REVIEW
Guohua Wang, Yong Cao, Tianding Wu, Chunyue Duan, Jianhuang Wu, Jianzhong Hu, Hongbin Lu
BACKGROUND: Cervical spondylotic myelopathy (CSM) is a degenerative disorder of the neck. Recent studies have reported the roles of single nucleotide polymorphisms and abnormal gene expression in the etiology and development of CSM. However, a systemic review of these findings is currently unavailable. METHODS: A systemic review of genetic factors of CSM was conducted through searching PubMed and EMbase databases. A total of 9 studies were included in this study, which included 8 genes: brain derived neurotrophic factor (BDNF), osteopontin (OPN), bone morphogenic protein (BMP) 4, collagen IX, vitamin D receptor (VDR), apolipoprotein E (ApoE), hypoxia-inducible factor α (HIF-1α), and cyclooxygenase 2 (COX-2)...
July 19, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28733721/factors-associated-with-postoperative-c5-palsy-after-expansive-open-door-laminoplasty-retrospective-cohort-study-using-multivariable-analysis
#10
Takashi Tsuji, Morio Matsumoto, Masaya Nakamura, Ken Ishii, Nobuyuki Fujita, Kazuhiro Chiba, Kota Watanabe
PURPOSE: The aim of the present study was to investigate the factors associated with C5 palsy by focusing on radiological parameters using multivariable analysis. METHODS: The authors retrospectively assessed 190 patients with cervical spondylotic myelopathy treated by open-door laminoplasty. Four radiographic parameters-the number of expanded lamina, C3-C7 angle, lamina open angle and space anterior to the spinal cord-were evaluated to clarify the factors associated with C5 palsy...
July 21, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28711563/application-of-neurite-orientation-dispersion-and-density-imaging-or-diffusion-tensor-imaging-to-quantify-the-severity-of-cervical-spondylotic-myelopathy-and-to-assess-postoperative-neurologic-recovery
#11
Genki Okita, Tetsuro Ohba, Tomohiro Takamura, Shigeto Ebata, Ryo Ueda, Hiroshi Onishi, Hirotaka Haro, Masaaki Hori
BACKGROUND CONTEXT: Surgical outcome and the severity of cervical spondylotic myelopathy (CSM) are unpredictable and cannot be estimated by conventional anatomical magnetic resonance imaging (MRI). The utility of diffusion tensor imaging (DTI) to quantify the severity of CSM and to assess postoperative neurologic recovery has been investigated. However, whether conventional DTI should be applied in a clinical setting remains controversial. Neurite orientation dispersion and density imaging (NODDI) is a recently introduced model-based diffusion-weighted MRI technique that quantifies specific microstructural features related directly to neuronal morphology...
July 12, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28708041/microendoscopic-laminotomy-versus-conventional-laminoplasty-for-cervical-spondylotic-myelopathy-5-year-follow-up-study
#12
Akihito Minamide, Munehito Yoshida, Andrew K Simpson, Hiroshi Yamada, Hiroshi Hashizume, Yukihiro Nakagawa, Hiroshi Iwasaki, Shunji Tsutsui, Motohiro Okada, Masanari Takami, Shin-Ichi Nakao
OBJECTIVE The goal of this study was to characterize the long-term clinical and radiological results of articular segmental decompression surgery using endoscopy (cervical microendoscopic laminotomy [CMEL]) for cervical spondylotic myelopathy (CSM) and to compare outcomes to conventional expansive laminoplasty (ELAP). METHODS Consecutive patients with CSM who required surgical treatment were enrolled. All enrolled patients (n = 78) underwent CMEL or ELAP. All patients were followed postoperatively for more than 5 years...
July 14, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28704622/assessment-of-psychometric-properties-of-various-balance-assessment-tools-in-persons-with-cervical-spondylotic-myelopathy
#13
Alice Y Y Chiu, Marco Y C Pang
Study Design Clinical measurement; cross-sectional, repeated measures. Background Persons with cervical spondylotic myelopathy (CSM) are known to have balance impairments. The psychometric properties of various balance assessment tools have not been evaluated in this population. Objective To examine the floor and ceiling effects, item difficulty and item discrimination index, internal consistency, reliability, and validity of the Balance Evaluation Systems Test (BESTest), Mini-BESTest, Brief-BESTest and Berg balance scale (BBS) in persons with CSM...
July 13, 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28704332/the-image-diagnostic-classification-of-mr-t2-increased-signal-intensity-in-cervical-spondylotic-myelopathy-clinical-evaluation-using-quantitative-and-objective-assessment
#14
Masaaki Machino, Shiro Imagama, Kei Ando, Kazuyoshi Kobayashi, Kenyu Ito, Mikito Tsushima, Akiyuki Matsumoto, Masayoshi Morozumi, Satoshi Tanaka, Keigo Ito, Fumihiko Kato, Yoshihiro Nishida, Naoki Ishiguro
STUDY DESIGN: A prospective imaging study OBJECTIVE.: The study investigated whether the classification of increased signal intensity (ISI) using magnetic resonance imaging (MRI) reflects the severity of symptoms in patients with cervical spondylotic myelopathy (CSM). SUMMARY OF BACKGROUND DATA: Although the ISI on MRI in patients with CSM is observed, the degree of ISI has not been examined. The association between ISI and the surgical outcomes in cervical myelopathy remains controversial...
July 12, 2017: Spine
https://www.readbyqxmd.com/read/28703331/high-resolution-diffusion-tensor-imaging-in-cervical-spondylotic-myelopathy-a-preliminary-follow-up-study
#15
Li Guan, Xiaolong Chen, Yong Hai, Xiaodong Ma, Le He, Guangzhi Wang, Chun Yuan, Hua Guo
Diffusion imaging is a promising technique as it can provide microstructural tissue information and thus potentially show viable changes in spinal cord. However, the traditional single-shot imaging method is limited as a result of various image artifacts. In order to improve measurement accuracy, we used a newly developed, multi-shot, high-resolution, diffusion tensor imaging (DTI) method to investigate diffusion metric changes and compare them with T2 -weighted (T2W) images before and after decompressive surgery for cervical spondylotic myelopathy (CSM)...
July 13, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28701500/assessing-structure-and-function-of-myelin-in-cervical-spondylotic-myelopathy-evidence-of-demyelination
#16
Hanwen Liu, Erin L MacMillian, Catherine R Jutzeler, Emil Ljungberg, Alex L MacKay, Shannon H Kolind, Burkhard Mädler, David K B Li, Marcel F Dvorak, Armin Curt, Cornelia Laule, John L K Kramer
PURPOSE: To assess the extent of demyelination in cervical spondylotic myelopathy (CSM) using myelin water imaging (MWI) and electrophysiologic techniques. METHODS: Somatosensory evoked potentials (SSEPs) and MWI were acquired in 14 patients with CSM and 18 age-matched healthy controls. MWI was performed on a 3.0T whole body magnetic resonance scanner. Myelin water fraction (MWF) was extracted for the dorsal columns and whole cord. SSEPs and MWF were also compared with conventional MRI outcomes, including T2 signal intensity, compression ratio, maximum spinal cord compression (MSCC), and maximum canal compromise (MCC)...
August 8, 2017: Neurology
https://www.readbyqxmd.com/read/28692908/surgical-outcomes-of-laminoplasty-for-cervical-spondylotic-myelopathy-in-very-elderly-patients-older-than-80-years-time-from-symptom-onset-to-surgery-and-changes-in-spinal-cord-signal-intensity-on-mri
#17
Naoki Notani, Masashi Miyazaki, Shozo Kanezaki, Toshinobu Ishihara, Hiroshi Tsumura
OBJECTIVE: We aimed to assess the surgical outcomes of laminoplasty for cervical spondylotic myelopathy (CSM) in very elderly patients (older than 80 years), focusing specifically on the time from symptom onset to surgery and on the loss in spinal cord signal intensity on magnetic resonance imaging (MRI). PATIENTS AND METHODS: We retrospectively reviewed 100 consecutive patients (61 males and 39 females) with CSM who underwent laminoplasty between 2006 and 2014...
September 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28690192/suppression-of-osteogenic-differentiation-in-mesenchymal-stem-cells-from-patients-with-ossification-of-the-posterior-longitudinal-ligament-by-a-histamine-2-receptor-antagonist
#18
Xizhe Liu, Gentaro Kumagai, Kanichiro Wada, Toshihiro Tanaka, Taku Fujita, Ayako Sasaki, Ken-Ichi Furukawa, Yasuyuki Ishibashi
Mesenchymal stem cells (MSCs) in ossification of the posterior longitudinal ligament (OPLL) patients have a high propensity toward osteogenesis. Histamine receptor H2 (H2R) antagonists (H2 blockers) like famotidine decrease ossification in patients, by an unclear mechanism. To confirm that MSCs express H2R and to clarify how H2 blockers suppress osteogenic differentiation, we used spinal-ligament MSCs from patients with OPLL or with cervical spondylotic myelopathy (CSM) (control). The MSCs were treated with 10, 30, or 100nM famotidine for 7 or 21 days...
September 5, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28678119/risk-factors-for-and-clinical-outcomes-of-dysphagia-after-anterior-cervical-surgery-for-degenerative-cervical-myelopathy-results-from-the-aospine-international-and-north-america-studies
#19
Narihito Nagoshi, Lindsay Tetreault, Hiroaki Nakashima, Paul M Arnold, Giuseppe Barbagallo, Branko Kopjar, Michael G Fehlings
BACKGROUND: Although dysphagia is a common complication after anterior cervical decompression and fusion, important risk factors have not been rigorously evaluated. Furthermore, the impact of dysphagia on neurological and quality-of-life outcomes is not fully understood. The aim of this study was to determine the prevalence of and risk factors for dysphagia, and the impact of this complication on short and long-term clinical outcomes, in patients treated with anterior cervical decompression and fusion...
July 5, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28676461/cervical-burst-fracture-in-a-patient-with-contiguous-two-level-cervical-stand-alone-cages-a-case-report
#20
Rui Feng, Joshua Loewenstern, John Caridi
BACKGROUND: Cervical stand-alone interbody cages have seen increasingly wider use over the plate-and-screw construct in single-level anterior cervical discectomy and fusion (ACDF) in the treatment of cervical disc herniation and degenerative spondylotic conditions. Despite positive clinical outcomes, the efficacy and safety of using these devices in contiguous multi-level ACDF, however, has remained controversial. CASE DESCRIPTION: This report discusses a burst fracture seen as a complication in multi-level cervical stand-alone cage use...
July 1, 2017: World Neurosurgery
keyword
keyword
104981
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"