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spondylotic myelopathy

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https://www.readbyqxmd.com/read/28220607/neurological-and-spinal-manifestations-of-the-ehlers-danlos-syndromes
#1
Fraser C Henderson, Claudiu Austin, Edward Benzel, Paolo Bolognese, Richard Ellenbogen, Clair A Francomano, Candace Ireton, Petra Klinge, Myles Koby, Donlin Long, Sunil Patel, Eric L Singman, Nicol C Voermans
The Ehlers-Danlos syndromes (EDS) are a heterogeneous group of heritable connective tissue disorders characterized by joint hypermobility, skin extensibility, and tissue fragility. This communication briefly reports upon the neurological manifestations that arise including the weakness of the ligaments of the craniocervical junction and spine, early disc degeneration, and the weakness of the epineurium and perineurium surrounding peripheral nerves. Entrapment, deformation, and biophysical deformative stresses exerted upon the nervous system may alter gene expression, neuronal function and phenotypic expression...
February 21, 2017: American Journal of Medical Genetics. Part C, Seminars in Medical Genetics
https://www.readbyqxmd.com/read/28214458/cervical-spondylotic-myelopathy-a-review-of-clinical-diagnosis-and-treatment
#2
Jason Cuellar, Peter Passias
Cervical spondylotic myelopathy (CSM) is a functional disturbance in the spinal cord as a result of degenerative changes within the cervical spinal column. This review discusses the history of CSM and its diagnosis, including clinical presentation, physical exam, and imaging studies. The pathophysiology, natural history, and treatment options are also discussed with support of the recent literature.
January 2017: Bulletin of the Hospital for Joint Diseases
https://www.readbyqxmd.com/read/28207659/evaluation-of-dti-parameter-ratios-and-diffusion-tensor-tractography-grading-in-the-diagnosis-and-prognosis-prediction-of-cervical-spondylotic-myelopathy
#3
Kun Wang, Zhi Chen, Fan Zhang, Qingxin Song, Canglong Hou, Yixing Tang, Jun Wang, Shiyue Chen, Yun Bian, Qiang Hao, Hongxing Shen
STUDY DESIGN: Prospective cohort. OBJECTIVE: To explore the correlations between diffusion tensor imaging (DTI) ratios and diffusion tensor tractography (DTT) grading with clinical symptoms and outcomes of cervical spondylotic myelopathy (CSM). SUMMARY OF BACKGROUND DATA: In addition to magnetic resonance imaging (MRI) and computed tomography, DTI may be useful in understanding pathophysiology of spinal cord in earlier stages of the CSM but it may be confounded by age and cervical level, and previous studies had small sample sizes...
February 15, 2017: Spine
https://www.readbyqxmd.com/read/28198778/reply-to-the-letter-to-the-editor-routine-use-of-intraoperative-neuromonitoring-during-acdfs-for-the-treatment-of-spondylotic-myelopathy-and-radiculopathy-is-questionable-a-review-of-15-395-cases
#4
https://www.readbyqxmd.com/read/28198776/reply-to-the-letter-to-the-editor-routine-use-of-intraoperative-neuromonitoring-during-acdfs-for-the-treatment-of-spondylotic-myelopathy-and-radiculopathy-is-questionable-a-review-of-15-395-cases
#5
https://www.readbyqxmd.com/read/28185064/smith-robinson-procedure-with-and-without-caspar-plating-as-a-treatment-for-cervical-spondylotic-myelopathy-a-26-year-follow-up-of-23-patients
#6
Benedikt W Burkhardt, Moritz Brielmaier, Karsten Schwerdtfeger, Salam Sharif, Joachim M Oertel
PURPOSE: The purpose of this study was to assess long-term follow-up data after anterior cervical decompression and fusion (ACDF) with and without Caspar plating (ACDF + PS) for the treatment of cervical spondylotic myelopathy (CSM) with special focus on functional outcome, pain, and repeat surgery for adjacent segment disease (ASD). METHOD: Hospital records of 45 patients who were affected by CSM and underwent ACDF or ACDF + PS at least 17 years ago were reviewed...
February 9, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28183145/minimally-invasive-microscopic-posterior-cervical-decompression-simple-safe-and-effective
#7
Pierluigi Vergara
Background and Study Aims Cervical spondylotic myelopathy (CSM) is the most common cause of spinal cord dysfunction in the elderly population. Surgery is usually successful in preventing any deterioration, as well as improving functional status and quality of life. This study assesses the safety and efficacy of minimally invasive microscopic posterior cervical decompression for the treatment of CSM. Materials and Methods A retrospective review of patients with myelopathy from cervical stenosis treated with minimally invasive posterior cervical decompression was performed...
February 9, 2017: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/28175458/162%C3%A2-tobacco-smoking-and-outcomes-of-surgical-decompression-in-patients-with-symptomatic-degenerative-cervical-spondylotic-myelopathy
#8
Paul M Arnold, Branko Kopjar, Lindsay Tetreault, Hiroaki Nakashima, Michael G Fehlings
No abstract text is available yet for this article.
August 1, 2016: Neurosurgery
https://www.readbyqxmd.com/read/28175440/169%C3%A2-laminoplasty-vs-laminectomy-with-posterior-spinal-fusion-for-multilevel-cervical-spondylotic-myelopathy-matched-cohorts-of-regional-sagittal-balance
#9
Darryl Lau, Ethan A Winkler, Khoi Duc Than, Dean Chou, Praveen V Mummaneni
No abstract text is available yet for this article.
August 1, 2016: Neurosurgery
https://www.readbyqxmd.com/read/28168336/predictors-of-cervical-lordosis-loss-after-laminoplasty-in-patients-with-cervical-spondylotic-myelopathy
#10
Jing Tao Zhang, Jia Qi Li, Rui Jie Niu, Zhao Liu, Tong Tong, Yong Shen
PURPOSE: To determine whether radiological, clinical, and demographic findings in patients with cervical spondylotic myelopathy (CSM) were independently associated with loss of cervical lordosis (LCL) after laminoplasty. METHODS: The prospective study included 41 consecutive patients who underwent laminoplasty for CSM. The difference in C2-7 Cobb angle between the postoperative and preoperative films was used to evaluate change in cervical alignment. Age, sex, body mass index (BMI), smoking history, preoperative C2-7 Cobb angle, T1 slope, C2-7 range of motion (C2-7 ROM), C2-7 sagittal vertical axis (C2-7 SVA), and cephalad vertebral level undergoing laminoplasty (CVLL) were assessed...
February 6, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28156205/metabolite-and-functional-profile-of-patients-with-cervical-spondylotic-myelopathy
#11
Izabela Aleksanderek, Todd K Stevens, Sandy Goncalves, Robert Bartha, Neil Duggal
OBJECTIVE The goal of this study was to compare the recovery of neuronal metabolism and functional reorganization in the primary motor cortex (M1) between mild and moderate cervical spondylotic myelopathy (CSM) following surgical intervention. METHODS Twenty-eight patients with CSM underwent 3-T MRI scans that included spectroscopy and functional MRI, before surgery and 6 months postsurgery. The classification of severity was based on the modified Japanese Orthopaedic Association questionnaire. Mild and moderate myelopathy were defined by modified Japanese Orthopaedic Association scores > 12 of 18 (n = 15) and 9-12 (n = 13), respectively...
February 3, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28151914/can-tranexamic-acid-reduce-blood-loss-in-cervical-laminectomy-with-lateral-mass-screw-fixation-and-bone-grafting-a-retrospective-observational-study
#12
COMPARATIVE STUDY
Cheng-Cheng Yu, Wen-Jie Gao, Jun-Song Yang, Hua Gu, Ming Zhu Md, Kai Sun, Ding-Jun Hao
To assess the safety and efficacy of tranexamic acid (TXA) for decreasing perioperative blood loss in cervical laminectomy with lateral mass screw fixation and bone grafting (CLF), in which all surgical procedures are identical.From November 2014 to April 2016, we performed a retrospective comparative analysis of 119 patients with multilevel cervical spondylotic myelopathy who had undergone a CLF from C3 to C6 in our center. All surgeries were performed on the patients using a consistent, standard procedure...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28130164/does-dynamic-supine-magnetic-resonance-imaging-improve-the-diagnostic-accuracy-of-cervical-spondylotic-myelopathy-a-review-of-the-current-evidence
#13
REVIEW
Nanfang Xu, Shaobo Wang, Huishu Yuan, Xiaoguang Liu, Zhongjun Liu
PURPOSE: We aimed to critically analyze the current evidence regarding the role of dynamic supine MRI (dsMRI) in the evaluation of cervical spondylotic myelopathy (CSM). METHODS: 13 studies were identified through a comprehensive literature search performed in the PubMed, EMBASE, and ISI databases as fulfilling the inclusion criteria and were reviewed for subject characteristics, radiographical parameters, and salient findings. RESULTS: Studies herein reviewed suggested that dsMRI was able to detect new appearance or increased grade of medullary compression in at least 20% of patients and to demonstrate an average narrowing of the cervical canal by 20% (in comparison to the neutral position)...
January 24, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28127374/the-change-of-range-of-motion-at-anterior-compression-of-the-cervical-cord-after-laminoplasty-in-patients-with-cervical-spondylotic-myelopathy
#14
Yongjae Cho
OBJECTIVE: Degenerative diseases of the spine, such as cervical spondylotic myelopathy (CSM), are increasing among the old age population, and surgical treatment of CSM is becoming more and more common. The aim of this study was to investigate how functional recovery can be influenced by anterior compression of the spinal cord (ACS) after laminoplasty for treatment of patients with CSM. METHODS: We retrospectively analyzed 32 patients admitted to Ewha Womans Mok-Dong Hospital with CSM who underwent open-door laminoplasty from January 2012 to December 2014...
December 2016: Korean Journal of Spine
https://www.readbyqxmd.com/read/28125929/trans-synaptic-degeneration-of-motoneurons-distal-to-chronic-cervical-spinal-cord-compression-in-cervical-spondylotic-myelopathy
#15
Chaojun Zheng, Yu Zhu, Feizhou Lu, Xiaosheng Ma, Dong Tian, Jianyuan Jiang
OBJECTIVE: To assess the effect of chronic cervical spinal cord compression upon remote motor unit function in patients with cervical spondylotic myelopathy (CSM). METHODS: Fifty-three CSM patients and 47 healthy subjects were included. Bilateral motor unit number estimations (MUNEs) were recorded from both abductor digiti minimi and abductor pollicis brevis, and bilateral flexor carpi radialis (FCR) H-reflexes were examined in all subjects along with the nine-hole peg test (NHPT)...
January 26, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28120077/focus-on-functional-delayed-central-sleep-apnea-following-cervical-laminectomy-an-example-of-respiratory-dysfunction-in-restorative-neurosurgical-procedures
#16
Massimiliano Visocchi, Gerardo Iacopino, Antonino Germanò, Giuseppe Barbagallo
In sleep-related breathing disorders, sleep apnea is a clinical symptom that can be categorized as obstructive sleep apnea (OSA) or mixed apnea by analysis using polysomnography. The occurrence of delayed central sleep apnea (CSA) is an extremely rare complication of cervical laminectomy for spondylotic myelopathy. So far only three studies concerning such an event have been reported in the literature. Naim-ur-Rahman, in 1994, reported a case of postoperative CSA following C3-C6 laminectomy, and Visocchi and colleagues, in 2014, in two studies, stressed the lack of association with any other neurological sign of spinal cord damage...
2017: Acta Neurochirurgica. Supplement
https://www.readbyqxmd.com/read/28104281/-results-to-4-year-follow-up-of-the-treatment-of-the-cervical-stenosis-by-corpectomy-titanium-mesh-cage-and-anterior-plate-fixation
#17
Alejandro Antonio Reyes Sánchez, Luis Alberto Gameros Castañeda, Claudia Obil Chavarría, Armando Alpizar Aguirre, Barón Zárate Kalfópulos, Luis Miguel Rosales-Olivares
BACKGROUND: Cervical spondylotic myelopathy is caused by cervical stenosis. Several techniques have been described for the treatment of multilevel disease, such as the anterior corpectomy with titanium mesh cage and anterior cervical plate placement, which has the advantage of performing a wider decompression and using the same bone as graft. However, it has caused controversy since the collapse of the mesh cage continues being a major limitation of this procedure. MATERIAL AND METHOD: A prospective 4-year follow-up study was conducted in 7 patients diagnosed with cervical stenosis, who were treated surgically by one level corpectomy with titanium mesh cage and anterior cervical plate placement, evaluating them by radiographs and clinical scales...
January 16, 2017: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/28104259/utility-of-extension-views-in-spondylotic-myelopathy-mimicking-transverse-myelitis
#18
Brittani L Conway, Michelle J Clarke, Timothy J Kaufmann, Eoin P Flanagan
Cervical spondylotic myelopathy is a common cause of myelopathy and may mimic transverse myelitis. We report a 55 year-old lady with subacute myelopathy initially treated with glatiramer acetate for suspected clinically isolated syndrome. MRI head and spine revealed a single short cervical cord T2-hyperintense lesion with enhancement just below a region of moderate stenosis. Cerebrospinal fluid revealed elevated oligoclonal bands. Repeat MRI 7 months later showed persistent enhancement. Dynamic MRI revealed cord compression during extension...
January 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/28099187/a-comparative-study-of-anterior-decompression-with-fusion-and-posterior-decompression-with-laminoplasty-for-the-treatment-of-cervical-spondylotic-myelopathy-patients-with-large-anterior-compression-of-the-spinal-cord
#19
Takashi Hirai, Toshitaka Yoshii, Yoshiyasu Arai, Kenichiro Sakai, Ichiro Torigoe, Hidetsugu Maehara, Masaki Tomori, Takashi Taniyama, Hirokazu Sato, Atsushi Okawa
STUDY DESIGN: This is a retrospective observational single-center study. OBJECTIVES: To compare anterior decompression and fusion (ADF) and laminoplasty (LAMP) for the treatment of cervical spondylotic myelopathy (CSM) patients with large anterior compression in terms of clinical and radiologic outcomes. SUMMARY OF BACKGROUND DATA: We have reported that insufficient posterior decompression could be often seen after laminoplasty for CSM patients with preoperative anterior clearance of the spinal cord, defined as an interval <4 mm between the preoperative the modified K-line and anterior structure of the spinal canal at most compressive segment on sagittal T1-weighted magnetic resonance imaging...
January 17, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28087188/operative-fusion-of-multilevel-cervical-spondylotic-myelopathy-impact-of-patient-demographics
#20
Shearwood McClelland, Bryan J Marascalchi, Peter G Passias, Themistocles S Protopsaltis, Anthony K Frempong-Boadu, Thomas J Errico
Cervical spondylotic myelopathy (CSM) is the most common cause of spinal cord dysfunction in patients older than age 55, with operative management being a widely adopted approach. Previous work has shown that private insurance status, gender and patient race are predictive of the operative approach patients receive (anterior-only, posterior-only, combined anterior-posterior). The Nationwide Inpatient Sample from 2001 to 2010 was used to assess the potential role of multilevel CSM as a contributing factor in determining which operative approach CSM patients receive, as it is rare for an anterior-only approach to be sufficient for CSM patients requiring fusion of four or more involved levels...
January 10, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
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