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https://www.readbyqxmd.com/read/28430890/acceptability-comparison-between-hawley-retainers-and-vacuum-formed-retainers-in-orthodontic-adult-patients-a-single-centre-randomized-controlled-trial
#1
Mohammed Saleh, Mohammad Y Hajeer, Dieter Muessig
Background: Hawley retainers (HRs) and vacuum formed retainers (VFRs) are the most commonly used removable retainers in the orthodontic practice. Patients' cooperation in wearing these appliances is affected by the levels of discomfort and oral impairment. The evidence regarding their acceptably among orthodontic patients is limited. Aims: To compare the acceptability of HRs and VFRs over a 6-month period in a group of fixed orthodontic patients. Trial Design: Two-arm parallel-group randomized controlled trial...
April 19, 2017: European Journal of Orthodontics
https://www.readbyqxmd.com/read/28427835/maxillofacial-growth-and-speech-outcome-after-one-stage-or-two-stage-palatoplasty-in-unilateral-cleft-lip-and-palate-a-systematic-review
#2
Rajgopal R Reddy, Srinivas Gosla Reddy, Anitha Vaidhyanathan, Stefaan J Bergé, Anne Marie Kuijpers-Jagtman
BACKGROUND: The number of surgical procedures to repair a cleft palate may play a role in the outcome for maxillofacial growth and speech. The aim of this systematic review was to investigate the relationship between the number of surgical procedures performed to repair the cleft palate and maxillofacial growth, speech and fistula formation in non-syndromic patients with unilateral cleft lip and palate. MATERIAL AND METHODS: An electronic search was performed in PubMed/old MEDLINE, the Cochrane Library, EMBASE, Scopus and CINAHL databases for publications between 1960 and December 2015...
March 22, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28425186/association-studies-of-low-frequency-coding-variants-in-nonsyndromic-cleft-lip-with-or-without-cleft-palate
#3
Elizabeth J Leslie, Jenna C Carlson, John R Shaffer, Carmen J Buxó, Eduardo E Castilla, Kaare Christensen, Frederic W B Deleyiannis, Leigh L Field, Jacqueline T Hecht, Lina Moreno, Ieda M Orioli, Carmencita Padilla, Alexandre R Vieira, George L Wehby, Eleanor Feingold, Seth M Weinberg, Jeffrey C Murray, Mary L Marazita
Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is a group of common human birth defects with complex etiology. Although genome-wide association studies have successfully identified a number of risk loci, these loci only account for about 20% of the heritability of orofacial clefts. The "missing" heritability may be found in rare variants, copy number variants, or interactions. In this study, we investigated the role of low-frequency variants genotyped in 1995 cases and 1626 controls on the Illumina HumanCore + Exome chip...
April 19, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28422614/electronic-follow-up-of-developing-world-cleft-patients-a-digital-dream
#4
Tom W M Walker, Ambika Chadha, William Rodgers, Caroline Mills, Peter Ayliffe
OBJECTIVE: To identify potential access to telemedicine follow-up of children with clefts operated on a humanitarian mission. METHODS: A cross-sectional study of parents of children presenting to a humanitarian cleft lip and palate mission in a Provincial Hospital in the Philippines. A purpose designed questionnaire was used to assess access to electronic and digital resources that could be used to aid follow-up. Forty-five (N = 45) parents of children having primary cleft lip and or palate surgery participated...
April 19, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/28422603/factors-responsible-for-unfavorable-dental-arch-relationship-in-non-syndromic-unilateral-cleft-lip-and-palate-children
#5
Sanjida Haque, Mohammad Khursheed Alam, Mohd Fadhli Khamis
OBJECTIVES: Multiple factors are whispered to be crucial cause of unfavourable dental arch relationship in cleft lip and palate (CLP).This study aims to evaluate the dental arch relationship of Bangladeshi children with non syndromic unilateral cleft lip and palate (UCLP) following cheiloplasty and palatoplasty. Also to explore the various congenital (UCLP type, UCLP side, family history of cleft, family history of class III) and environmental (cheiloplasty, palatoplasty) factors that affects dental arch relationship of UCLP patients...
2017: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28422192/polymorphisms-at-1q32-8q24-and-17q22-loci-are-associated-with-nonsyndromic-cleft-lip-with-or-without-cleft-palate-risk-in-the-slovak-population
#6
Jan Salagovic, Lucia Klimcakova, Marianna Zabavnikova, Jana Behunova, Terezia Hudakova, Jozef Fedeles, Agata Molnarova, Ludmila Podracka
BACKGROUND: Nonsyndromic cleft lip with or without cleft palate (nsCL/P) is the most common orofacial birth defect with an aetiology involving both genetic and environmental factors. Genome-wide association studies (GWAS) have identified several genomic susceptibility regions for nsCL/P. In the present study, the three well established single nucleotide polymorphisms (SNPs) identified by GWAS (rs987525 at 8q24, rs7078160 at 10q25, and rs227731 at 17q22 loci) and one SNP identified by candidate gene study (rs642961 in IRF6 gene at 1q32 locus) were analysed for an association with nsCL/P in Slovak population...
March 30, 2017: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
https://www.readbyqxmd.com/read/28417474/first-trimester-sonographic-evaluation-of-palatine-clefts-a-novel-diagnostic-approach
#7
Selvaraj Ravi Lakshmy, Selvaraj Deepa, Nity Rose, Senthilkumar Mookan, Joy Agnees
OBJECTIVES: Sonographic evaluation of the palate is a difficult task, and most palatine clefts are diagnosed in the neonatal period because of the limitations of 2-dimensional (2D) sonography. The objective is to describe a sonographic technique based on 2D markers for screening of palatine clefts during the nuchal translucency scan and to assess the ability of 3-dimensional (3D) sonography in imaging the normal and abnormal palate. METHODS: A total of 2014 women who enrolled for first-trimester screening were included in this prospective study...
April 18, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28416097/long-term-effect-of-presurgical-nasoalveolar-molding-on-growth-of-maxillary-arch-in-unilateral-cleft-lip-and-palate-randomized-controlled-trial
#8
V Shetty, R K Agrawal, H F Sailer
The objective of this study was to investigate the long-term effect of presurgical nasoalveolar molding (PNAM) on growth of the maxillary arch through early childhood until 6 years of age in complete unilateral cleft lip and palate (UCLP) patients presenting for PNAM at different ages. Complete UCLP patients who were treated at our centre were divided into two groups. The study group underwent PNAM and was further subdivided into three subgroups (PNAM initiated within 1 month, between 1 and 6 months, and between 6 and 12 months of age in subgroup I, II, and III, respectively)...
April 13, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28414872/a-scoping-review-of-outcomes-related-to-orthodontic-treatment-measured-in-cleft-lip-and-palate
#9
REVIEW
A Tsichlaki, K O'Brien, A Johal, P S Fleming
The aim of this study was to identify and summarize the outcomes measured in orthodontic studies of children with cleft lip and/or palate. The objectives were to categorize the outcomes into pre-determined domains and to explore whether any domains were under-represented. Electronic databases and grey literature were searched until December 2016 to identify all studies of orthodontic treatment interventions in children and adolescents with cleft lip and palate. Abstracts and subsequently eligible full-text articles were screened independently and in duplicate by two reviewers...
May 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/28413596/non-syndromic-multiple-supernumerary-premolars-clinicoradiographic-report-of-five-cases
#10
Renu Tanwar, Vipul Jaitly, Aadya Sharma, Rashmi Heralgi, Munish Ghangas, Ankur Bhagat
Hyperdontia or supernumerary teeth in both arches without any syndromic manifestation are extremely rare. Supernumerary teeth are commonly associated with Gardner's syndrome, cleft lip and palate, cleidocranial dysplasia and trichorhinopha-langeal syndrome. Five cases of non-syndromic multiple premolars of maxillary and mandibular arches in Indian patients are presented here. This case series reports three cases with multiple (9 in maximum), bilaterally impacted and erupted supernumerary teeth and two cases with supernumerary premolars in non-syndromic cases from Indian patients...
2017: Journal of Dental Research, Dental Clinics, Dental Prospects
https://www.readbyqxmd.com/read/28412787/-progress-in-studies-on-the-genetic-risk-factors-for-nonsyndromic-cleft-lip-or-palate-in-china
#11
Y Q Huang
Cleft lip and palate is the most common congenital defects of oral and maxillofacial region in human beings. The etiology of this malformation is complex, with both genetic and environmental causal factors are involved. To provide a better understanding in the genetic etiology of cleft lip or palate, the author summarized recent years studies based on Chinese population. Those researches included validation of some candidate genes for cleft lip or palate, using genome wide association analysis which included six independent cohorts from China to elucidate the genetic architecture of non-syndromic cleft lip with or without cleft palate in Chinese population and finally found a new susceptibility locus...
April 9, 2017: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/28412785/-functional-repair-of-cleft-lip-from-anatomical-resetting-to-biomechanical-simulation
#12
N B Yin
We are no longer entangled in the anatomical resetting of the labial-nasal muscle itself, but the sight to the muscle fiber level, to study the relationship between the muscle fiber force line and the labial-nasal shape. In the past ten years, we focused on the lip of nasal muscle fiber anatomy, imageology and biomechanics, carried out a series of research works, realized the three-dimensional (3D) visualization of small labial-nasal muscle fiber, established configuration models of normal and cleft lip with nasal muscle fibers, and put forward the hypothesis of naso-labial muscle tension band...
April 9, 2017: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/28408147/an-anatomical-subunit-based-outcome-assessment-scale-for-bilateral-cleft-lip-and-palate
#13
K Bonanthaya, P N Shetty, P S Fudalej, D D Rao, S Bitra, M Pabari, M Rachwalski
As there is currently no internationally accepted outcome measurement tool available for complete bilateral cleft lip and palate (CBCLP), the goal of this prospective study was to develop a numerical evaluation scale that allows reliable scoring of this cleft deformity. Our cohort comprised 121 Indian subjects with CBCLP who underwent surgical repair (mean age at time of surgery 6.53 months) using a modified Millard technique. A panel of three professionals evaluated each subject's outcome of bilateral cleft lip repair 6 months postoperatively on two-dimensional (2D) full-face photographs in the frontal view and worm's eye view...
April 10, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28403134/early-computer-aided-design-computer-aided-modeling-planned-le-fort-i-advancement-with-internal-distractors-to-treat-severe-maxillary-hypoplasia-in-cleft-lip-and-palate
#14
Catherine S Chang, Jordan Swanson, Jason Yu, Jesse A Taylor
Traditionally, maxillary hypoplasia in the setting of cleft lip and palate is treated via orthognathic surgery at skeletal maturity, which condemns these patients to abnormal facial proportions during adolescence. The authors sought to determine the safety profile of computer-aided design/computer-aided modeling (CAD/CAM) planned, Le Fort I distraction osteogenesis with internal distractors in select patients presenting at a young age with severe maxillary retrusion. The authors retrospectively reviewed our "early" Le Fort I distraction osteogenesis experience-patients performed for severe maxillary retrusion (≥12 mm underjet), after canine eruption but prior to skeletal maturity-at a single institution...
April 11, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28403023/incidence-of-le-fort-surgery-in-a-mature-cohort-of-patients-with-cleft-lip-and-palate
#15
Cecilia Dalle Ore, Anna Schoenbrunner, Michael Brandel, Nicola Kronstadt, Joyce McIntyre, Marilyn Jones, Amanda Gosman
Primary repair of cleft lip and palate occurs early in life, but ideal timing of these interventions remains controversial. Prior research has indicated that a later palate repair may improve patients' midfacial growth long term, whereas optimal timing of lip repair to maximize midfacial growth has not been identified.The purpose of this study is to analyze a large, diverse cohort of patients with cleft lip and palate to determine whether timing of primary palate repair and primary lip repair contributed significantly to subsequent orthognathic surgery...
April 11, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28403008/a-new-design-for-reconstruction-about-nasal-dimensions-during-the-primary-repair-of-unilateral-cleft-lip
#16
Ren-Kai Liu, Cheng-Hao Li, Jiayu Shi, Bing Shi
No abstract text is available yet for this article.
February 15, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28403006/reply-not-all-clefts-are-created-equal-patterns-of-hospital-based-care-use-among-children-with-cleft-lip-and-palate-within-4-years-of-initial-surgery-published-in-plastic-and-reconstructive-surgery-of-june-2016
#17
Camille H A L Guillaume, E van Drie, Corstiaan Breugem
No abstract text is available yet for this article.
February 15, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28402597/gene-gene-interaction-of-single-nucleotide-polymorphisms-in-16p13-3-may-contribute-to-the-risk-of-non-syndromic-cleft-lip-with-or-without-cleft-palate-in-chinese-case-parent-trios
#18
Dongjing Liu, Hong Wang, Holger Schwender, Mary L Marazita, Zhuqing Wang, Yuan Yuan, Ping Wang, Kung Yee Liang, Yah Huei Wu-Chou, Mengying Wang, Bing Shi, Hongping Zhu, Tao Wu, Terri H Beaty
Non-syndromic cleft lip with or without cleft palate (NSCL/P) is a common birth defect with a complex and heterogeneous etiology. A recent genome-wide association study (GWAS) among Chinese populations has identified a new region at 16p13.3 as being associated with NSCL/P, which requires further replication. Here, we attempted to replicate and further clarify the genetic association between this region and NSCL/P, as well as testing for potential gene-gene (G × G) and gene-environment (G × E) interactions...
April 12, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28402064/use-of-psychotropic-medications-and-visits-to-psychiatrists-and-psychologists-among-individuals-with-nonsyndromic-oral-clefts-a-population-based-cohort-study
#19
Dorthe Almind Pedersen, Ida Hageman, George L Wehby, Kaare Christensen
BACKGROUND: Oral clefts (OCs) are among the most common congenital malformations and can have a large impact on the life of the affected individual. Research findings regarding the psychological and psychosocial consequences of OC are inconclusive. METHODS: Using Danish nationwide registers, we investigated redeemed prescriptions of psychotropic medication during 1996 to 2012 and visits to psychiatrists and psychologists during 1996 to 2011 among individuals born with nonsyndromic OC in Denmark between 1936 and 2009 and a comparison cohort of individuals without OC...
April 12, 2017: Birth Defects Res
https://www.readbyqxmd.com/read/28399025/incidence-of-le-fort-surgery-in-a-mature-cohort-of-patients-with-cleft-lip-and-palate
#20
Cecilia Dalle Ore, Anna Schoenbrunner, Michael Brandel, Nicola Kronstadt, Joyce McIntyre, Marilyn Jones, Amanda Gosman
Primary repair of cleft lip and palate occurs early in life, but ideal timing of these interventions remains controversial. Prior research has indicated that a later palate repair may improve patients' midfacial growth long term, whereas optimal timing of lip repair to maximize midfacial growth has not been identified.The purpose of this study is to analyze a large, diverse cohort of patients with cleft lip and palate to determine whether timing of primary palate repair and primary lip repair contributed significantly to subsequent orthognathic surgery...
May 2017: Annals of Plastic Surgery
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