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https://www.readbyqxmd.com/read/28329810/wisdom-and-hard-times-the-ameliorating-effect-of-wisdom-on-the-negative-association-between-adverse-life-events-and-well-being
#1
Monika Ardelt, Dilip V Jeste
Objectives: Old age is characterized by many physical and social losses that adversely affect subjective well-being (SWB). Yet, past studies have shown that wisdom tends to be positively related to SWB in old age, particularly under adverse circumstances. We tested whether three-dimensional wisdom, measured as a combination of cognitive, reflective, and compassionate (affective) personality qualities, moderated the inverse association between adverse life events and well-being. Method: A sample of 994 adults aged 51-99 years (M = 77) from the Successful AGing Evaluation (SAGE) study and structural equation models with well-being as a latent variable were used to test the hypothesis...
October 20, 2016: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/28318723/pan-european-survey-of-the-topical-ocular-use-of-cyclosporine-a
#2
A Labbé, C Baudouin, D Ismail, M Amrane, J-S Garrigue, A Leonardi, F C Figueiredo, G Van Setten, M Labetoulle
OBJECTIVE: To assess medical practices surrounding the use of topical ocular cyclosporine A across European Union nations. METHODS: Key stakeholders (ophthalmologists, hospital pharmacists, regulatory health authorities) from European Union member states were interviewed by telephone using a semi-structured, open-ended questionnaire. Ophthalmologists responded to questions about practice patterns of cyclosporine A use (prescription frequency, indication, dosage), pharmacists about cyclosporine A formulations (composition, manufacturing process, quality control, distribution), and the regulatory authorities about market authorization and pharmacovigilance for various cyclosporine A products...
March 16, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28295948/nurses-experiences-of-delivering-care-in-acute-inpatient-mental-health-settings-a-narrative-synthesis-of-the-literature
#3
REVIEW
Marianne Wyder, Carolyn Ehrlich, David Crompton, Leianne McArthur, Caroline Delaforce, Fiona Dziopa, Shulamit Ramon, Elizabeth Powell
Inpatient psychiatric care requires a balance between working with consumers' priorities and goals, managing expectations of the community, legal, professional and service responsibilities. In order to improve service delivery within acute mental health units, it is important to understand the constraints and facilitating factors for good care. We conducted a systematic narrative synthesis, where findings of qualitative studies are synthesised to generate new insights. 21 articles were identified. Our results show that personal qualities, professional skills as well as environmental factors all influence the ability to provide recovery focused care...
March 14, 2017: International Journal of Mental Health Nursing
https://www.readbyqxmd.com/read/28289528/clinical-cardiac-regenerative-studies-in-children
#4
REVIEW
Imre J Pavo, Ina Michel-Behnke
Although the incidence of pediatric heart failure is low, the mortality is relatively high, with severe clinical symptoms requiring repeated hospitalization or intensive care treatment in the surviving patients. Cardiac biopsy specimens have revealed a higher number of resident human cardiac progenitor cells, with greater proliferation and differentiation capacity, in the neonatal period as compared with adults, demonstrating the regeneration potential of the young heart, with rising interest in cardiac regeneration therapy in critically ill pediatric patients...
February 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28286623/effective-management-of-bone-fractures-with-the-illuminoss%C3%A2-photodynamic-bone-stabilization-system-initial-clinical-experience-from-the-european-union-registry
#5
Thomas Gausepohl, Dietmar Pennig, Steffen Heck, Sascha Gick, Paul A Vegt, Jon E Block
The IlluminOss(®) system (IS) uses a light-curable polymer contained within an inflatable balloon catheter, forming a patient customized intramedullary implant. A registry was established in Germany and The Netherlands to prospectively collect technical and clinical outcomes in patients treated with IS for fractures of the phalange, metacarpal, radius, ulna, distal radius, fibula, clavicle and/or olecranon. Humeral, femoral, tibial and pelvic fractures were included under compassionate use. Procedural success included successful placement of the device at the target fracture site and achievement of fracture stabilization...
February 20, 2017: Orthopedic Reviews
https://www.readbyqxmd.com/read/28283311/septic-arthritis-in-a-native-knee-due-to-corynebacterium-striatum
#6
Juan Molina Collada, Alicia Rico Nieto, Macarena Díaz de Bustamante Ussia, Alejandro Balsa Criado
We describe a case of septic arthritis in a native knee due to Corynebacterium striatum, gram-positive bacilli that are usually commensal organisms of skin and mucosal membranes, but are seldom implicated in native septic arthritis. An 84-year-old man with Corynebacterium striatum septic arthritis of his native left knee and no response to conventional antibiotic therapy. Thus, the patient was allowed to take dalbavancin for compassionate use, with an excellent clinical outcome. This case emphasizes de role of Corynebacterium striatum in native joint infections and highlights the importance of early detection and appropriate treatment in improving the clinical outcome...
March 7, 2017: Reumatología Clinica
https://www.readbyqxmd.com/read/28282256/new-evidence-on-end-of-life-hospital-utilization-for-enhanced-health-policy-and-services-planning
#7
Donna M Wilson, Ye Shen, Stephen Birch
BACKGROUND: Long-standing concern exists over hospital use by people near or at the end of life (EOL) related to the appropriateness, quality, and cost of care in hospital. It is widely believed that most people die in hospital after an escalation in hospital use over the last year of life. As most deaths in high-income countries are not sudden or unexpected, opportunities exist for planning compassionate, effective, and evidence-based EOL care. OBJECTIVE: Gain current population-based evidence for EOL health policy and services planning...
March 10, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28278701/efficacy-and-toxicity-of-compassionate-ibrutinib-use-in-relapsed-refractory-chronic-lymphocytic-leukemia-in-poland-analysis-of-the-polish-adult-leukemia-group-palg
#8
Elżbieta Iskierka-Jażdżewska, Marek Hus, Krzysztof Giannopoulos, Elżbieta Mądro, Jadwiga Hołojda, Magdalena Piotrowska, Jan M Zaucha, Weronika Piszczek, Agnieszka Szeremet, Małgorzata Wojciechowska, Paweł Steckiewicz, Wanda Knopińska-Posłuszny, Marek Osowiecki, Joanna Drozd-Sokołowska, Beata Kumiega, Sławomira Kyrcz-Krzemień, Janusz Hałka, Marek Dudziński, Paulina Wieszczy, Tadeusz Robak, Krzysztof Warzocha, Krzysztof Jamroziak
No abstract text is available yet for this article.
February 28, 2017: Leukemia & Lymphoma
https://www.readbyqxmd.com/read/28264791/more-than-5000-patients-with-metastatic-melanoma-in-europe-per-year-do-not-have-access-to-recommended-first-line-innovative-treatments
#9
L Kandolf Sekulovic, K Peris, A Hauschild, A Stratigos, J-J Grob, P Nathan, R Dummer, A-M Forsea, C Hoeller, H Gogas, L Demidov, C Lebbe, C Blank, J Olah, L Bastholt, D Herceg, B Neyns, R Vieira, J Hansson, P Rutkowski, I Krajsova, M Bylaite-Bucinskiene, I Zalaudek, J Maric-Brozic, N Babovic, M Banjin, K Putnik, G Weinlich, V Todorovic, K Kirov, J Ocvirk, A Zhukavets, M Kukushkina, L De La Cruz Merino, A Ymeri, M Risteski, C Garbe
BACKGROUND: Despite the efficacy of innovative treatments for metastatic melanoma, their high costs has led to disparities in cancer care among different European countries. We analysed the availability of these innovative therapies in Europe and estimated the number of patients without access to first-line recommended treatment per current guidelines of professional entities such as the European Society for Medical Oncology (ESMO), the European Organisation for Research and Treatment of Cancer (EORTC), the European Association of Dermato-Oncology (EADO), and European Dermatology Forum (EDF)...
March 2, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28262699/gs-5734-and-its-parent-nucleoside-analog-inhibit-filo-pneumo-and-paramyxoviruses
#10
Michael K Lo, Robert Jordan, Aaron Arvey, Jawahar Sudhamsu, Punya Shrivastava-Ranjan, Anne L Hotard, Mike Flint, Laura K McMullan, Dustin Siegel, Michael O Clarke, Richard L Mackman, Hon C Hui, Michel Perron, Adrian S Ray, Tomas Cihlar, Stuart T Nichol, Christina F Spiropoulou
GS-5734 is a monophosphate prodrug of an adenosine nucleoside analog that showed therapeutic efficacy in a non-human primate model of Ebola virus infection. It has been administered under compassionate use to two Ebola patients, both of whom survived, and is currently in Phase 2 clinical development for treatment of Ebola virus disease. Here we report the antiviral activities of GS-5734 and the parent nucleoside analog across multiple virus families, providing evidence to support new indications for this compound against human viruses of significant public health concern...
March 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28262583/response-to-anti-programmed-cell-death-protein-1-antibodies-in-men-treated-for-platinum-refractory-germ-cell-cancer-relapsed-after-high-dose-chemotherapy-and-stem-cell-transplantation
#11
Stefanie Zschäbitz, Felix Lasitschka, Boris Hadaschik, Ralf-Dieter Hofheinz, Kathleen Jentsch-Ullrich, Marcus Grüner, Dirk Jäger, Carsten Grüllich
INTRODUCTION: Treatment options for patients with platinum refractory metastatic germ cell tumours (GCT) relapsing after high-dose chemotherapy and autologous stem cell transplantation are limited and survival is poor. Antibodies directed against programmed cell death protein-1 (PD-1) and programmed cell death ligand-1 (PD-L1) are currently assessed within clinical trials. We present updated data on our experience with checkpoint inhibitors as a compassionate use off-label treatment attempt for highly-pretreated patients with GCT and provide an overview of the current literature on PD-L1 expression in this rare tumour entity...
March 2, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28257351/the-experience-of-intense-pain-nursing-management-and-interventions
#12
Norma Kiser-Larson
Personal stories of illness give depth to otherwise clinical descriptions of diagnoses. This article offers an autobiographical narrative of complications after total knee replacement surgery. Diagnosis and nursing management of acute compartment syndrome, nociceptive and neuropathic origins of pain, pharmacologic and nursing interventions for pain, the use of prayer in illness, and compassionate caring from a Christian perspective are discussed.
April 2017: Journal of Christian Nursing: a Quarterly Publication of Nurses Christian Fellowship
https://www.readbyqxmd.com/read/28252903/-compassionate-nursing-care-the-experience-of-italian-nurses
#13
Paola De Carlo, Denise Guerra, Maria Luisa Rega, Caterina Galletti
AIM: In international nursing literature compassion and compassionate care has acquired a considerable importance and it's considered to be a growing phenomenon. The approach to the application of compassionate care to patients is clearly not well-defined in Italian nursing. The aim of this study is to define what compassionate care is through the analysis of Italian nurses' experiences. METHOD: The research is based on a qualitative method. Content analysis was used to analyze the transcript data...
October 2016: Professioni Infermieristiche
https://www.readbyqxmd.com/read/28245794/user-experiences-with-a-web-based-self-help-intervention-for-partners-of-cancer-patients-based-on-acceptance-and-commitment-therapy-and-self-compassion-a-qualitative-study
#14
Nadine Köhle, Constance H C Drossaert, Jasmijn Jaran, Karlein M G Schreurs, Irma M Verdonck-de Leeuw, Ernst T Bohlmeijer
BACKGROUND: Partners of cancer patients are the cornerstone of supportive cancer care. They assume different roles and responsibilities that optimally support the patient. Such support is highly demanding, and many partners report (mental) health problems. However, many of them do not use professional supportive care themselves. Offering a Web-based self-help intervention based on Acceptance and Commitment Therapy (ACT) and self-compassion could be an important resource to support this group...
February 28, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28245161/oncology-nurses-perceptions-of-end-of-life-care-in-a-tertiary-cancer-centre-in-qatar
#15
Izette Larraine M Libo-On, Abdulqadir J Nashwan
BACKGROUND: Nurses who work in oncology settings may lack the knowledge and skills required for end-of-life (EoL) care. A clear understanding of nurses' perceptions of EoL care is crucial for the successful improvement of care for terminally ill patients with cancer. Although many studies have underlined nurses' perspectives on EoL care, this is the first such study conducted on oncology nurses in Qatar. PURPOSE: This study primarily sought to measure nurses' perceptions of EoL care at the National Center for Cancer Care and Research (NCCCR) in Qatar...
February 2, 2017: International Journal of Palliative Nursing
https://www.readbyqxmd.com/read/28241824/treatment-of-chronic-non-healing-ulcers-using-autologous-platelet-rich-plasma-a-case-series
#16
Manish Suthar, Saniya Gupta, Suhail Bukhari, Venkatesh Ponemone
BACKGROUND: Non-healing ulcers are a major health problem worldwide and have great impact at personal, professional and social levels, with high cost in terms of human and material resources. Recalcitrant non-healing ulcers are inevitable and detrimental to the lower limb and are a major cause of non-traumatic lower limb amputations. Application of autologous Platelet Rich Plasma (PRP) has been a major breakthrough for the treatment of non-healing and diabetic foot ulcers, as it is an easy and cost-effective method, and provides the necessary growth factors that enhance tissue healing...
February 27, 2017: Journal of Biomedical Science
https://www.readbyqxmd.com/read/28224866/the-governing-body-nurse-as-a-clinical-commissioning-group-nurse-leader
#17
Angela Dempsey, Virginia Minogue
Aim The aim of this study was to understand governing body nurses' perspective of their effect on, and leadership of, clinical commissioning groups (CCGs). Method Semi-structured face-to-face and telephone interviews were conducted with a sample of governing body nurses, CCG chairs and regional chief nurses. A total of 23 individuals were interviewed. Findings Governing body nurses were overwhelmingly positive about their role and believed they had a positive effect on the CCG governing body. Specifically, they provided leadership for the quality agenda and compassionate practice...
February 22, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28222689/family-centred-interventions-by-primary-healthcare-services-for-indigenous-early-childhood-wellbeing-in-australia-canada-new-zealand-and-the-united-states-a-systematic-scoping-review
#18
Janya McCalman, Marion Heyeres, Sandra Campbell, Roxanne Bainbridge, Catherine Chamberlain, Natalie Strobel, Alan Ruben
BACKGROUND: Primary healthcare services in Australia, Canada, New Zealand and the United States have embraced the concept of family-centred care as a promising approach to supporting and caring for the health of young Indigenous children and their families. This scoping review assesses the quality of the evidence base and identifies the published literature on family- centred interventions for Indigenous early childhood wellbeing. METHODS: Fourteen electronic databases, grey literature sources and the reference lists of Indigenous maternal and child health reviews were searched to identify relevant publications from 2000 to 2015...
February 21, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28219644/the-usefulness-of-18f-fluorocholine-pet-ct-in-the-detection-of-recurrence-of-central-nervous-system-primary-neoplasms
#19
A Montes, A Fernández, V Camacho, C de Quintana, O Gallego, J Craven-Bartle, D López, J Molet, B Gómez-Ansón, I Carrió
AIM: To study the usefulness of (18)F-fluorocholine (FCH) in detecting the recurrence of primary brain tumours. MATERIAL AND METHODS: A prospective study was conducted on brain PET/CT with FCH for compassionate use in 21 patients with suspected recurrence of a primary brain tumour. The distribution by pathology was: three grade ii astrocytomas, three grade iii astrocytomas, one grade ii oligodendroglioma, three grade iii oligodendrogliomas, one grade iii oligoastrocytoma, four glioblastoma multiform, one gliomatosis cerebri, and five meningiomas...
February 16, 2017: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/28215044/developing-caring-conversations-in-care-homes-an-appreciative-inquiry
#20
Belinda Dewar, Tamsin MacBride
Relationship-centred practice is key to delivering quality care in care homes. Evidence is strong about the centrality of human interaction in developing relationships that promote dignity and compassion. The Caring Conversations framework is a framework for delivering compassionate care based on human interactions that was developed in the acute healthcare setting. The key attributes are: be courageous, connect emotionally, be curious, consider other perspectives, collaborate, compromise and celebrate. This paper reports on a study to explore its relevance to the care home setting and the development of an educational intervention, based on the framework, to enhance development of human interaction...
February 19, 2017: Health & Social Care in the Community
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