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https://www.readbyqxmd.com/read/28231174/optimization-of-ultrasound-assisted-extraction-preliminary-characterization-and-in-vitro-antioxidant-activity-of-polysaccharides-from-green-pea-pods
#1
Maryam Jalili Safaryan, Ali Ganjloo, Mandana Bimakr, Soheila Zarringhalami
In this study, ultrasound-assisted extraction of green pea pod polysaccharide (GPPP) was investigated and optimized using a central composite response surface design coupled with a numerical optimization technique. The effects of ultrasonic power (50-150 W), sonication time (20-80 min), ratio of water to raw material (20:1-40:1 mL/g) and extraction temperature (40-80 °C) on polysaccharide extraction yield were studied. The maximum extraction yield was obtained with a sonication power of 135.34 W, extraction time of 48...
November 28, 2016: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28230965/fluorine-functionalized-graphene-quantum-dots-as-inhibitor-against-hiapp-amyloid-aggregation
#2
Maryam Yousaf, Huan Huang, Ping Li, Chen Wang, Yanlian Yang
Fibrillar deposits of the human islet amyloid polypeptide (hIAPP) is considered as a root of Type II diabetes mellitus. Fluorinated graphene quantum dots (FGQDs) are new carbon nanomaterials with unique physicochemical properties containing highly electronegative F atoms. Herein we report a single step synthesis method of FGQDs with an inhibitory effect on aggregation and cytotoxicity of hIAPP in vitro. Highly fluorescent and water dispersible FGQDs, less than 3 nm in size were synthesized by the microwave-assisted hydrothermal method...
February 23, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/28229060/vitamin-d-levels-in-children-with-adenotonsillar-hypertrophy-and-otitis-media-with-effusion
#3
Alimohamad Asghari, Zohreh Bagheri, Maryam Jalessi, Mohammad Mahdi Salem, Elahe Amini, Sahand GhalehBaghi, Sepideh Bakhti
INTRODUCTION: Vitamin D has been suggested to play a considerable role in the function of the immune system in various infectious, inflammatory, and autoimmune conditions. Otitis media with effusion (OME), defined as the presence of non-purulent fluid within the middle ear without signs or symptoms of suppurative otitis media, has a number of inflammatory predisposing factors. This study was designed to explore the association between vitamin D deficiency and OME. MATERIALS AND METHODS: In this cross-sectional study, 74 children aged 2-7 years with an obstructive indication for adenotonsillectomy were included...
January 2017: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28228883/posttraumatic-mandibular-asymmetry-presenting-in-a-young-adult
#4
Mahnaz Sheikhi, Maryam Ghazizadeh, Mohammad Mahdi Salehi
One of the most common sites of injury of the facial skeleton is mandibular condyle. However, it is the least diagnosed site of trauma in the head and neck regions. A trauma to the mandible and specifically condylar zone during childhood, may lead to asymmetry or mandibular bilateral distortion, which is usually manifested in the second decade of life when the etiology is unknown to most people. This report is about an adult male complaining about facial asymmetry with an unknown source. Obvious clicking at the right side and shorter right ramus and condyle's head deviation directed us to a childhood trauma and fracture...
March 2017: Radiology case reports
https://www.readbyqxmd.com/read/28228528/clinical-genetic-and-structural-basis-of-congenital-adrenal-hyperplasia-due-to-11%C3%AE-hydroxylase-deficiency
#5
Ahmed Khattab, Shozeb Haider, Ameet Kumar, Samarth Dhawan, Dauood Alam, Raquel Romero, James Burns, Di Li, Jessica Estatico, Simran Rahi, Saleel Fatima, Ali Alzahrani, Mona Hafez, Noha Musa, Maryam Razzghy Azar, Najoua Khaloul, Moez Gribaa, Ali Saad, Ilhem Ben Charfeddine, Berenice Bilharinho de Mendonça, Alicia Belgorosky, Katja Dumic, Miroslav Dumic, Javier Aisenberg, Nurgun Kandemir, Ayfer Alikasifoglu, Alev Ozon, Nazli Gonc, Tina Cheng, Ursula Kuhnle-Krahl, Marco Cappa, Paul-Martin Holterhus, Munier A Nour, Daniele Pacaud, Assaf Holtzman, Sun Li, Mone Zaidi, Tony Yuen, Maria I New
Congenital adrenal hyperplasia (CAH), resulting from mutations in CYP11B1, a gene encoding 11β-hydroxylase, represents a rare autosomal recessive Mendelian disorder of aberrant sex steroid production. Unlike CAH caused by 21-hydroxylase deficiency, the disease is far more common in the Middle East and North Africa, where consanguinity is common often resulting in identical mutations. Clinically, affected female newborns are profoundly virilized (Prader score of 4/5), and both genders display significantly advanced bone ages and are oftentimes hypertensive...
February 22, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28228154/circulating-species-of-leishmania-at-microclimate-area-of-boulemane-province-morocco-impact-of-environmental-and-human-factors
#6
Asmae Hmamouch, Mahmoud Mohamed El Alem, Maryam Hakkour, Fatima Amarir, Hassan Daghbach, Khalid Habbari, Hajiba Fellah, Khadija Bekhti, Faiza Sebti
BACKGROUND: Cutaneous leishmaniasis (CL) is widely distributed in Morocco where its geographical range and incidence are related to environmental factors. This study aimed to examine the impact of several factors on the distribution of CL in Boulemane Province, which is characterized by several microclimates, and to identify the Leishmania species circulating in these areas. METHODS: Ordinary least squares regression (OLSR) analysis was performed to study the impact of poverty, vulnerability, population density, urbanization and bioclimatic factors on the distribution of CL in this province...
February 22, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28228095/evaluating-the-expression-profile-and-stability-of-different-ucoe-containing-vector-combinations-in-mab-producing-cho-cells
#7
Fatemeh Nematpour, Fereidoun Mahboudi, Behrouz Vaziri, Vahid Khalaj, Samira Ahmadi, Maryam Ahmadi, Saedeh Ebadat, Fatemeh Davami
BACKGROUND: As the demand for monoclonal antibodies (mAb) increases, more efficient expression methods are required for their manufacturing process. Transcriptional gene silencing is a common phenomenon in recombinant cell lines which leads to expression reduction and instability. There are reports on improved antibody expression in ubiquitous chromatin opening element (UCOE) containing both heavy and light chain gene constructs. Here we investigate the impact of having these elements as part of the light chain, heavy chain or both genes during cell line development...
February 22, 2017: BMC Biotechnology
https://www.readbyqxmd.com/read/28228072/curcumin-and-endothelial-function-evidence-and-mechanisms-of-protective-effects
#8
Maryam Saberi Karimian, Matteo Pirro, Thomas P Johnston, Muhammed Majeed, Amirhossein Sahebkar
BACKGROUND: The endothelium is a large paracrine organ regulating cell growth, vascular tone and thrombogenicity as well as platelet and leukocyte interactions. Endothelial function can be assessed by non-invasive techniques [e.g. flow-mediated vasodilation, nitroglycerin-mediated dilation and pulse wave velocity] and measuring specific circulating biomarkers [cell adhesion molecules, endothelial microparticles and endothelial progenitor cells]. Impaired endothelial function plays a key role in the development of atherosclerosis, arterial hypertension, heart failure, ischemia-reperfusion injury, Alzheimer's disease and other conditions...
February 22, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28227965/multiscale-brain-machine-interface-decoders
#9
Han-Lin Hsieh, Maryam M Shanechi, Han-Lin Hsieh, Maryam M Shanechi, Han-Lin Hsieh, Maryam M Shanechi
Brain-machine interfaces (BMI) have vastly used a single scale of neural activity, e.g., spikes or electrocorticography (ECoG), as their control signal. New technology allows for simultaneous recording of multiple scales of neural activity, from spikes to local field potentials (LFP) and ECoG. These advances introduce the new challenge of modeling and decoding multiple scales of neural activity jointly. Such multi-scale decoding is challenging for two reasons. First, spikes are discrete-valued and ECoG/LFP are continuous-valued, resulting in fundamental differences in statistical characteristics...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226853/generalized-binary-noise-stimulation-enables-time-efficient-identification-of-input-output-brain-network-dynamics
#10
Yuxiao Yang, Maryam M Shanechi, Yuxiao Yang, Maryam M Shanechi, Yuxiao Yang, Maryam M Shanechi
Identification of input-output (IO) dynamics of brain networks in response to electrical stimulation is essential for devising closed-loop therapies for neurological disorders such as major depression. A critical component for accurate IO identification is the stimulation input design. The time available for open-loop stimulation to perform system identification is typically limited. While our prior design of a binary noise (BN) modulated input pattern satisfies the requirements for optimal identification and clinical safety, it does not incorporate any prior information about the underlying network...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226612/automatic-threshold-optimization-in-nonlinear-energy-operator-based-spike-detection
#11
Muhammad H Malik, Maryam Saeed, Awais M Kamboh, Muhammad H Malik, Maryam Saeed, Awais M Kamboh, Muhammad H Malik, Maryam Saeed, Awais M Kamboh
In neural spike sorting systems, the performance of the spike detector has to be maximized because it affects the performance of all subsequent blocks. Non-linear energy operator (NEO), is a popular spike detector due to its detection accuracy and its hardware friendly architecture. However, it involves a thresholding stage, whose value is usually approximated and is thus not optimal. This approximation deteriorates the performance in real-time systems where signal to noise ratio (SNR) estimation is a challenge, especially at lower SNRs...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225570/washless-method-enables-multilayer-coating-of-an-aggregation-prone-nanoparticulate-drug-delivery-system-with-enhanced-yields-colloidal-stability-and-scalability
#12
Lamees Nayef, Rafael Castiello, Maryam Tabrizian
Aggregation is frequently encountered during coating nanoparticles, especially when the core is not solid and the coating polyelectrolytes are weak. Here, the coating of a nanoliposome with two weak polyelectrolytes, alginate and chitosan, is investigated. First, quartz crystal microbalance with dissipation, atomic force microscopy, scanning electron microscopy, and energy dispersive spectroscopy analyses confirm the feasibility of firm adsorption of up to 16 layers of weak polyelectrolytes to the liposomal surface...
February 22, 2017: Macromolecular Bioscience
https://www.readbyqxmd.com/read/28224032/prevalence-of-intestinal-parasites-in-referred-individuals-to-the-medical-centers-of-tonekabon-city-mazandaran-province
#13
Samira Shahdoust, Maryam Niyyati, Ali Haghighi, Eznoallah Azargashb, Mohammad Reza Khataminejad
AIM: The aim of the present study was to determine the prevalence of intestinal parasites and their relation with socio-demographic data in referred individuals to the medical centers in Tonekabon, Mazandaran province, 2015. BACKGROUND: Due to the climatic and ecological conditions in Mazandaran province, determination of the status of intestinal parasites among referred individuals to the medical centers of Tonekabon city can help researchers and healthcare services to prevent and/or control of parasitic infection in this region...
December 2016: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28224031/first-report-of-tasmanian-sheep-strain-g2-genotype-isolated-from-iranian-goat-using-the-high-resolution-melting-hrm-analysis
#14
Ahmad Hosseini-Safa, Mohammad Ali Mohag Hegh, Nader Pestechian, Maryam Ganji, Rasoul Mohammadi, Reza Mahmoudi Lamouki, Mohammad Rostami-Nejad
AIM: The present study was aimed to evaluate E. granulosus genotypes isolated from goats using HRM analysis in Isfahan province. BACKGROUND: Cystic echincoccosis, so-called hydatidosis, is widespread infection caused by the larval stage of Echinococcus granulosus. This is an important zoonotic disease worldwide, especially in the developing countries such as Iran. To date, molecular studies mainly based on the mitochondrial DNA sequences have identified distinct genotypes termed G1-G10 which can differ in some characteristics such as the growth and infectivity to different intermediate hosts or the survival rate in the definitive hosts that are important for the development of control strategies...
December 2016: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28224030/safety-and-effectiveness-of-sleeve-gastrectomy-versus-gastric-bypass-one-year-results-of-tehran-obesity-treatment-study-tots
#15
Maryam Barzin, Alireza Khalaj, Mohammad Ali Motamedi, Pravin Shapoori, Fereidoun Azizi, Farhad Hosseinpanah
AIM: We aimed to compare the effectiveness and safety of sleeve gastrectomy versus gastric bypass at one-year. BACKGROUND: Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) are the two most commonly performed bariatric procedures worldwide. METHODS: Patients from a prospectively collected database who presented to a specialized bariatric center and underwent a primary bariatric procedure between March 2013 and April 2015 were included and compared regarding major and minor complication rates and weight loss parameters at 6 and 12 months...
December 2016: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28224028/evaluation-of-antimicrobial-susceptibility-and-integron-carriage-in-helicobacter-pylori-isolates-from-patients
#16
Mehdi Goudarzi, Mohsen Heidary, Mehdi Azad, Maryam Fazeli, Hossein Goudarzi
AIM: The purpose of this study was to determine the antibiotic susceptibility pattern and distribution of integron in H. pylori isolates collected from patients referred to private health care centers in Tehran, Iran. BACKGROUND: Antibiotic resistance is the main reason for failure of Helicobacter pylori therapy. Integrons as genetic reservoirs play main roles in the dissemination of antimicrobial resistance gene. METHODS: During a 12-month cross-sectional study period, 65 H...
December 2016: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28224025/lack-of-association-between-interleukin-28b-gene-polymorphisms-rs8099917g-t-rs12979860-c-t-and-susceptibility-to-chronic-hepatitis-c-virus-infection-tehran-iran
#17
Maryam Karkhane, Seyed Reza Mohebbi, Pedram Azimzadeh, Mahsa Saeedi Niasar, Mohamad Reza Sarbazi, Afsaneh Sharifian, Afshin Mohammad Alizadeh
AIM: Chronic Hepatitis C infection is a critical health problem worldwide, which caused by hepatitis C virus (HCV). Interleukin 28B (IL28B) is a determinant factor in disease progression and also susceptibility to chronic HCV infection. BACKGROUND: The most significant aim of this study is to analyze the association between IL28B gene polymorphisms with susceptibility to chronic HCV infection in Iranian population. METHODS: This study follows a case- control study design, in which, 288 patients with chronic hepatitis C and 250 healthy individuals were genotyped for IL28B polymorphisms (rs12979860 C/T and rs8099917 G/T)...
December 2016: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28223343/associations-of-steroid-sex-hormones-and-sex-hormone-binding-globulin-with-the-risk-of-type-2-diabetes-in-women-a-population-based-cohort-study-and-meta-analysis
#18
Taulant Muka, Jana Nano, Loes Jaspers, Cindy Meun, Wichor M Bramer, Albert Hofman, Abbas Dehghan, Maryam Kavousi, Joop S E Laven, Oscar H Franco
It remains unclear whether endogenous sex hormones (ESH) are associated with risk of type 2 diabetes (T2D) in women. Data of 3,117 postmenopausal women participants of the Rotterdam Study were analyzed to examine whether ESH and sex hormone-binding globulin (SHBG) were associated with the risk of incident T2D. Additionally, we performed a systematic review and meta-analysis of studies assessing the prospective association of ESH and SHBG with T2D in women. During a median follow-up of 11.1 years, we identified 384 incident cases of T2D in the Rotterdam Study...
March 2017: Diabetes
https://www.readbyqxmd.com/read/28222930/the-importance-of-smiling
#19
Maryam Arshad
No abstract text is available yet for this article.
February 17, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28222399/improved-yeast-delivery-of-fluconazole-with-a-nanostructured-lipid-carrier-system
#20
Hamid Reza Kelidari, Maryam Moazeni, Roghayeh Babaei, Majid Saeedi, Jafar Akbari, Parisa Islami Parkoohi, Mojtaba Nabili, Atefeh Abdollahi Gohar, Katayoun Morteza-Semnani, Ali Nokhodchi
Despite the growing trends in the number of patients at risk for invasive fungal infections, management with current antifungal agents results in complications due to changes in the epidemiology and drug susceptibility of invasive fungal infections. In the present research fluconazole-loaded nanostructured lipid carriers were prepared using probe ultrasonication techniques and investigated the efficacy of the optimal formulation on a large number of Candida species. The morphology of the obtained nanostructured lipid carriers was characterized by transmission-electron microscopy...
February 17, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
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