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Chiari dti

Ramona Woitek, Daniela Prayer, Michael Weber, Gabriele Amann, Rainer Seidl, Dieter Bettelheim, Veronika Schöpf, Peter C Brugger, Julia Furtner, Ulrika Asenbaum, Gregor Kasprian
OBJECTIVES: This prenatal MRI study evaluated the potential of diffusion tensor imaging (DTI) metrics to identify changes in the midbrain of fetuses with Chiari II malformations compared to fetuses with mild ventriculomegaly, hydrocephalus and normal CNS development. METHODS: Fractional anisotropy (FA) and apparent diffusion coefficient (ADC) were calculated from a region of interest (ROI) in the midbrain of 46 fetuses with normal CNS, 15 with Chiari II malformations, eight with hydrocephalus and 12 with mild ventriculomegaly...
May 2016: European Radiology
Gunes Orman, Kevin Yuqi Wang, Ximin Li, Carol Thompson, Thierry A G M Huisman, Izlem Izbudak
PURPOSE: Obtaining fast, reliable, high-resolution diffusion tensor imaging (DTI) of the pediatric cervical spinal cord (CSC) is challenging, given the multitude of technical limitations involved. Overcoming these limitations may further potentiate DTI as a valuable quantitative tool in evaluating the pediatric CSC. METHODS: Sixteen patients (9 girls and 7 boys) with hypoxic brain injury, craniocervical junction malformations, and head trauma were included in this retrospective study...
August 2015: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
Jennifer Williams McVige, Jody Leonardo
Chiari malformation type I (CMI) involves the caudal displacement of the cerebellar tonsils through the foramen magnum with resultant brainstem compression in some individuals. Due to pathophysiologic changes, secondary conditions may arise, such as syringohydromyelia (SH) and scoliosis. This disorder is unique, as the diagnosis is confirmed through radiologic findings. At times CMI is discovered incidentally on neuroimaging, but more frequently a patient will present with specific symptoms, the most common being a prototypic occipital headache...
June 2015: Current Pain and Headache Reports
Erik H Middlebrooks, Kaan Yagmurlu, Jeffrey A Bennett, Sharatchandra Bidari
PURPOSE: The purpose of our study is to compare cadaver dissections with in vivo diffusion tensor imaging (DTI) to determine the position of the cervicomedullary junction (CMJ) relative to the readily identified anatomic landmarks, namely the obex and olivary bodies (olives), in normal subjects. The information gained from this study would allow further investigation into abnormalities of the CMJ, such as Chiari malformation, without the need for time-intensive tractography studies. METHODS: Six formalin-fixed human cadaver brains were compared with DTI studies in 15 normal controls...
July 2015: Surgical and Radiologic Anatomy: SRA
Tadesse Eshetu, Avner Meoded, George I Jallo, Benjamin S Carson, Thierry Agm Huisman, Andrea Poretti
AIM: Chiari type I malformation (C1M) may be symptomatic or asymptomatic as an incidental finding. In this retrospective study, we applied diffusion tensor imaging (DTI) to study the brainstem and cerebellar white matter tracts in C1M. METHOD: Diffusion tensor imaging (DTI) data were acquired on a 1.5T MR-scanner using balanced pairs of diffusion gradients along 20 non-collinear directions. Measurements from regions of interest in each pontine corticospinal tract, medial leminscus, and middle cerebellar peduncle (MCP) and in the lower brainstem were obtained for fractional anisotropy and mean, axial, and radial diffusivity...
August 2014: Developmental Medicine and Child Neurology
N Passi, A J Degnan, L M Levy
Papilledema, defined as swelling of the optic disc, frequently occurs in the setting of increased ICP and in a variety of medical conditions, including pseudotumor cerebri, sinus thrombosis, intracerebral hemorrhage, frontal lobe neoplasms, and Chiari malformation. Noninvasive imaging of the ON is possible by using MR imaging, with a variety of findings occurring in the setting of papilledema, including flattening of the posterior sclera, protrusion of the optic disc, widening of the ONS, and tortuosity of the ON...
May 2013: AJNR. American Journal of Neuroradiology
Manoj Kumar, Ram K S Rathore, Arti Srivastava, Santosh Kumar Yadav, Sanjay Behari, Rakesh Kumar Gupta
BACKGROUND: The aim of this study was to examine changes in normal-appearing deep gray and white matter regions of the brain in patients with Chiari I malformation compared with controls using diffusion tensor imaging (DTI) and to correlate these changes with neuropsychological (NP) test scores. METHODS: Conventional magnetic resonance imaging, DTI, and neuropsychological tests were performed on 10 patients (median age 27 years, range 18 to 36 years) with Chiari I malformation and 10 age/sex-matched healthy controls...
July 2011: World Neurosurgery
Laura Merlini, Joel Fluss, Christian Korff, Sylviane Hanquinet
Partial rhombencephalosynapsis (PRECS) has been recently reported in association with Chiari II (CII). However, its existence as a true malformation is challenged due to the anatomical changes potentially induced by CII. The aim of this report was to investigate the contribution of midbrain/hindbrain tractography in this setting. A 13-year-old boy with a known CII malformation and operated myelomeningocele was referred for brain imaging after a first complex partial seizure. In addition to the classical features of CII, MRI showed partially fused cerebellar hemispheres and multiple supratentorial abnormalities...
March 2012: Cerebellum
Xiawei Ou, Charles M Glasier, Jeffrey H Snow
BACKGROUND: Macrostructural abnormalities in cerebral white matter in patients with myelomeningocele are well known, but microstructural abnormalities are not as well studied. OBJECTIVE: The aim of this study was to evaluate cerebral white matter in adolescents with myelomeningocele using diffusion tensor imaging (DTI), and to investigate the effects of ventricular dilation and CSF shunt presence on white matter microstructure in these patients. MATERIALS AND METHODS: DTI and T1-weighted 3-D (T1-3-D) MRI were performed on nine adolescents with myelomeningocele and Chiari II malformation and nine age-matched controls...
November 2011: Pediatric Radiology
Amir Zolal, Petr Vachata, Ales Hejcl, Alberto Malucelli, Robert Bartos, Martin Sames
INTRODUCTION: The paper focuses on the use of diffusion tensor imaging (DTI) in the evaluation of one case of Chiari III malformation. CASE REPORT: In the case discussed, DTI was used to delineate the position of large descending tracts within the malformation and the reconstructed images were used to plan the surgical procedure. DISCUSSION: The clinical and imaging findings, the technical aspects of the DTI fiber tract reconstruction and the outcome are summarized...
July 2010: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
C Herweh, M Akbar, M Wengenroth, M Blatow, J Mair-Walther, N Rehbein, E Nennig, J P Schenk, S Heiland, C Stippich
Chiari II-malformation is a complex congenital deformity of the brain which is frequently associated with hydrocephalus. Abnormalities of the corpus callosum are known to occur in the majority of patients. The objective of the present study was to study the microstructure of the corpus callosum (CC) and the anterior commissure (AC) to differentiate between different mechanisms of damage to these structures. We investigated 6 patients with Chiari II-malformation and 6 well-matched healthy volunteers employing T1-weighted 3D imaging and diffusion tensor imaging (DTI) to determine the fractional anisotropy (FA) and cross-sectional area of the CC and AC, as well as with neuropsychological testing...
January 15, 2009: NeuroImage
Khader M Hasan, Thomas J Eluvathingal, Larry A Kramer, Linda Ewing-Cobbs, Maureen Dennis, Jack M Fletcher
PURPOSE: To quantify microstructural abnormalities in the major association pathways of children affected by spina bifida myelomeningocele (SBM) and shunted hydrocephalus using whole-brain diffusion tensor imaging (DTI). MATERIALS AND METHODS: The institutional review board approved this Health Insurance Portability and Accountability Act (HIPAA)-compliant study and written informed consent/assent were obtained prior to the study. The 69 participants included 38 children with SBM and shunted hydrocephalus (age mean +/- SD = 12...
April 2008: Journal of Magnetic Resonance Imaging: JMRI
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