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https://www.readbyqxmd.com/read/29792983/impact-of-genetic-influence-on-serum-total-and-free-25-hydroxyvitamin-d-in-humans
#1
Balázs Szili, Boglárka Szabó, Péter Horváth, Bence Bakos, Györgyi Kirschner, János P Kósa, Erzsébet Toldy, Zsuzsanna Putz, Péter Lakatos, Ádám Tabák, István Takács
Serum 25-hydroxyvitamin D /25OHD/ levels in humans are determined primarily by environmental factors such as UV-B radiation and diet, including vitamin D intake. Although some genetic determinants of 25OHD levels have been shown, the magnitude of this association has not yet been clarified. The present study evaluates the genetic contribution to total- /t-25OHD/ and free-25OHD /f-25OHD/ in a representative sample of the Hungarian population (n = 462). The study was performed at the end of winter to minimize the effect of sunlight, which is a major determinant of serum vitamin D levels...
May 21, 2018: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29792961/composite-films-of-regenerate-cellulose-with-chitosan-and-polyvinyl-alcohol-evaluation-of-water-adsorption-mechanical-and-optical-properties
#2
Patricia Cazón, Manuel Vázquez, Gonzalo Velazquez
The aim of this study was to develop composite films from cellulose, chitosan and polyvinyl alcohol to obtain environmentally friendly materials. Toughness, burst strength, distance to burst and water adsorption properties were measured and analysed as a function of cellulose (3-5%), chitosan (0-1%) and polyvinyl alcohol (0-4%) contents. Polynomial models were obtained. Light-barrier properties, transparency, morphology, structural and thermal analyses were assessed. Results showed that chitosan and polyvinyl alcohol enhanced the mechanical properties of cellulose-based films...
May 21, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29790516/ultrafast-excited-state-decay-of-natural-uv-filters-from-intermolecular-hydrogen-bonds-to-a-conical-intersection
#3
Peter S Sherin, Yuri P Tsentalovich, Eric Vauthey, Enrico Benassi
Kynurenines (KNs) are natural UV filters of the human eye lens, protecting the eye tissues from solar UV radiation. Key points of their effective protection are the intramolecular charge transfer (ICT) in the excited state and the fast dissipation of absorbed light energy into heat via the intermolecular H-bonds. Herein we report that the introduction of an unsaturated double bond in the amino acid side chain, operating as an ICT-enhancing electron donor group, drastically accelerates the internal conversion (IC) due to a conical intersection (CI) between the potential energy surfaces of the excited and ground states...
May 23, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29773927/influence-of-meteorological-factors-on-the-level-and-characteristics-of-culturable-bacteria-in-the-air-in-gliwice-upper-silesia-poland
#4
Ewa Brągoszewska, Józef S Pastuszka
Numerous studies have focused on occupational and indoor environments because people spend more than 90% of their time in them. Nevertheless, air is the main source of bacteria in indoors, and outdoor exposure is also crucial. Worldwide studies have indicated that bacterial concentrations vary among different types of outdoor environments, with considerable seasonal variations as well. Conducting comprehensive monitoring of atmospheric aerosol concentrations is very important not only for environmental management but also for the assessment of the health impacts of air pollution...
2018: Aerobiologia
https://www.readbyqxmd.com/read/29772514/the-effect-of-polymer-aging-on-the-uptake-of-fuel-aromatics-and-ethers-by-microplastics
#5
Axel Müller, Roland Becker, Ute Dorgerloh, Franz-Georg Simon, Ulrike Braun
Microplastics are increasingly entering marine, limnic and terrestrial ecosystems worldwide, where they sorb hydrophobic organic contaminants. Here, the sorption behavior of the fuel-related water contaminants benzene, toluene, ethyl benzene and xylene (BTEX) and four tertiary butyl ethers to virgin and via UV radiation aged polypropylene (PP) and polystyrene (PS) pellets was investigated. Changes in material properties due to aging were recorded using appropriate polymer characterization methods, such as differential scanning calorimetry, Fourier transform infrared spectroscopy, gel permeation chromatography, X-ray photoelectron spectroscopy, and microscopy...
May 14, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29770941/degradation-of-ampicillin-antibiotic-by-electrochemical-processes-evaluation-of-antimicrobial-activity-of-treated-water
#6
Jorge Vidal, Cesar Huiliñir, Rocío Santander, Javier Silva-Agredo, Ricardo A Torres-Palma, Ricardo Salazar
Ampicillin (AMP) is an antibiotic widely used in hospitals and veterinary clinics around the world for treating infections caused by bacteria. Therefore, it is common to find traces of this antibiotic in wastewater from these entities. In this work, we studied the mineralization of this antibiotic in solution as well as the elimination of its antimicrobial activity by comparing different electrochemical advanced oxidation processes (EAOPs), namely electro-oxidation with hydrogen peroxide (EO-H2 O2 ), electro-Fenton (EF), and photo electro-Fenton (PEF)...
May 17, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29770935/insight-into-elemental-mercury-hg-0-removal-from-flue-gas-using-uv-h-2-o-2-advanced-oxidation-processes
#7
Changsong Zhou, Zijian Song, Hongmin Yang, Hao Wu, Ben Wang, Jie Yu, Lushi Sun
Elemental mercury (Hg0 ) emitted from coal-fired power plants and municipal solid waste (MSW) incinerators has caused great harm to the environment and human beings. The strong oxidized • OH radicals produced by UV/H2 O2 advanced oxidation processes were studied to investigate the performance of Hg0 removal from simulated flue gases. The results showed that when H2 O2 concentration was 1.0 mol/L and the solution pH value was 4.1, the UV/H2 O2 system had the highest Hg0 removal efficiency. The optimal reaction temperature was approximately 50 °C and Hg0 removal was inhibited when the temperature was higher or lower...
May 16, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29770731/antibiotics-mineralization-by-electrochemical-and-uv-based-hybrid-processes-evaluation-of-the-synergistic-effect
#8
Salatiel Wohlmuth da Silva, Alan Nelson Arenhart Heberle, Alexia Pereira Santos, Marco Antônio Siqueira Rodrigues, Valentín Pérez-Herranz, Andréa Moura Bernardes
Antibiotics are not efficiently removed in conventional wastewater treatments. In fact, different Advanced Oxidation Process (AOPs), including ozone, peroxide, UV radiation, among others, are being investigated in the elimination of microcontaminants. Most of AOPs proved to be efficient on the degradation of antibiotics, but the mineralization is on the one hand not evaluated or on the other hand not high. At this work, the UV-based hybrid process, namely Photo-assisted electrochemical Oxidation (PEO), was applied aiming the mineralization of microcontaminants such as the antibiotics Amoxicillin (AMX), Norfloxacin (NOR) and Azithromycin (AZI)...
May 17, 2018: Environmental Technology
https://www.readbyqxmd.com/read/29768725/kinetics-thermodynamics-and-modelling-of-amido-black-dye-photodegradation-in-water-using-co-tio-2-nanoparticles
#9
Imran Ali, Omar M L Alharbi, Zeid A Alothman, Ahmad Yacine Badjah
Titanium oxide nanoparticles were doped with copper and characterized by XRD, FT-IR, TEM and SEM. The surface morphology was spherical with 15-26 nm as particle size. The doped titanium oxide (Co/TiO2 ) nanomaterial was used for photodegradation of amido black dye in water. The maximum photodegradation of amido black obtained was 90%. The values of free energy, and enthalpy were negative, indicating spontaneous photodegradation of amido black dye. The photodegradation of amido black dye obeyed first order kinetic model...
May 16, 2018: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/29768722/genoprotective-effect-of-phyllanthus-orbicularis-extract-against-uva-uvb-and-solar-radiation
#10
Marioly Vernhes Tamayo, André Passaglia Schuch, Teiti Yagura, Luis Baly Gil, Carlos Frederico Martins Menck, Angel Sánchez-Lamar
One approach to protect the human skin against harmful effects of solar ultraviolet (UV) radiation is to use natural products as photoprotectors. In this work, the extract from specie Phyllanthus orbicularis K was evaluated as a protective agent against the photodamage by UVB, UVA artificial lamps and environmental sunlight exposure. The plasmid DNA solutions were exposed to radiations using the DNA-dosimeter system in presence of plant extract. The DNA repair enzymes, E. coli Formamidopyrimidine-DNA glycosylase (Fpg) and T4 bacteriophage endonuclease V (T4-endo V), were employed to discriminate oxidized DNA damage and cyclobutane pyrimidine dimers (CPD) respectively...
May 16, 2018: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/29765529/-myc-gene-amplification-is-a-rare-event-in-atypical-fibroxanthoma-and-pleomorphic-dermal-sarcoma
#11
Timo Gaiser, Daniela Hirsch, Azadeh Orouji, Marisa Bach, Peter Kind, Doris Helbig, Alexander Quaas, Jochen Utikal, Alexander Marx, Maria Rita Gaiser
Atypical fibroxanthoma (AFX) and pleomorphic dermal sarcoma (PDS) are rare malignancies typically occurring in elderly patients and predominantly located in skin regions exposed to UV-light. Thus, a role of UV-radiation-induced damage for AFX and PDS tumorigenesis has been postulated. MYC gene amplification has been demonstrated as a distinctive feature of radiation-induced angiosarcoma. In order to investigate whether chronic exposure to UV-light might also lead to MYC copy number changes, 51 AFX and 24 PDS samples were retrospectively analyzed for MYC amplification by fluorescence in situ hybridization using a MYC and a CEP8 gene probe...
April 20, 2018: Oncotarget
https://www.readbyqxmd.com/read/29761305/uv-b-susceptibility-and-photoreactivation-in-embryonic-development-of-the-two-spotted-spider-mite-tetranychus-urticae
#12
Yoshio Yoshioka, Tetsuo Gotoh, Takeshi Suzuki
Developmental errors are often induced in the embryos of many organisms by environmental stress. Ultraviolet-B radiation (UV-B) is one of the most serious environmental stressors in embryonic development. Here, we investigated susceptibility to UV-B (0.5 kJ m-2 ) in embryos of the two-spotted spider mite, Tetranychus urticae, to examine the potential use of UV-B in control of this important agricultural pest worldwide. Peak susceptibility to UV-B (0% hatchability) was found in T. urticae eggs 36-48 h after oviposition at 25 °C, which coincides with the stages of morphogenesis forming the germ band and initial limb primordia...
May 14, 2018: Experimental & Applied Acarology
https://www.readbyqxmd.com/read/29760079/selection-and-environmental-adaptation-along-a-path-to-speciation-in-the-tibetan-frog-nanorana-parkeri
#13
Guo-Dong Wang, Bao-Lin Zhang, Wei-Wei Zhou, Yong-Xin Li, Jie-Qiong Jin, Yong Shao, He-Chuan Yang, Yan-Hu Liu, Fang Yan, Hong-Man Chen, Li Jin, Feng Gao, Yaoguang Zhang, Haipeng Li, Bingyu Mao, Robert W Murphy, David B Wake, Ya-Ping Zhang, Jing Che
Tibetan frogs, Nanorana parkeri , are differentiated genetically but not morphologically along geographical and elevational gradients in a challenging environment, presenting a unique opportunity to investigate processes leading to speciation. Analyses of whole genomes of 63 frogs reveal population structuring and historical demography, characterized by highly restricted gene flow in a narrow geographic zone lying between matrilines West (W) and East (E). A population found only along a single tributary of the Yalu Zangbu River has the mitogenome only of E, whereas nuclear genes of W comprise 89-95% of the nuclear genome...
May 14, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29759485/roles-of-alternative-rna-splicing-of-the-bif-1-gene-by-srrm4-during-the-development-of-treatment-induced-neuroendocrine-prostate-cancer
#14
Yu Gan, Yinan Li, Zhi Long, Ahn R Lee, Ning Xie, Jessica M Lovnicki, Yuxin Tang, Xiang Chen, Jiaoti Huang, Xuesen Dong
Treatment-induced neuroendocrine prostate cancer (t-NEPC) is an aggressive subtype of prostate cancer (PCa) that becomes more prevalent when hormonal therapy, chemotherapy, or radiation therapy is applied to patients with metastatic prostate adenocarcinoma (AdPC). How AdPC cells survive these anti-cancer therapies and progress into t-NEPC remains unclear. By comparing the whole transcriptomes between AdPC and t-NEPC, we identified Bif-1, an apoptosis-associated gene, which undergoes alternative RNA splicing in t-NEPC...
May 11, 2018: EBioMedicine
https://www.readbyqxmd.com/read/29758545/protection-against-uv-induced-oxidative-stress-and-dna-damage-by-amazon-moss-extracts
#15
A S Fernandes, J L Mazzei, H Evangelista, M R C Marques, E R A Ferraz, I Felzenszwalb
Amazon mosses, such as Holomitriopsis laevifolia and Leucobryum sp. are naturally exposed to high levels of solar ultraviolet (UV) radiation. Theoretically, under environmental stress conditions these mosses have developed protective chemical and metabolic strategies against UV damage, by way of biosynthesis of secondary metabolites, such as flavonoids. The present paper aimed to evaluate the free-radical scavenging activity, and the photoprotective, mutagenic and photomutagenic potencies of the methanolic (ME), aqueous (AE), hydroalcoholic (HE), ethanolic (EE) extracts of H...
April 27, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29752876/quantifying-direct-dna-damage-in-the-basal-layer-of-skin-exposed-to-uv-radiation-from-sunbeds
#16
Isla Rose Mary Barnard, Patrick Tierney, Catherine Louise Campbell, Lewis McMillan, Harry Moseley, Ewan Eadie, Christian Tom Alcuin Brown, Kenneth Wood
Non-melanoma and melanoma skin cancers are attributable to DNA damage caused by ultraviolet (UV) radiation exposure. One DNA photoproduct, the Cyclobutane Pyrimidine Dimer (CPD), is believed to lead to DNA mutations caused by UV radiation. Using radiative transfer simulations, we compare the number of CPDs directly induced by UV irradiation from artificial and natural UV sources (a standard sunbed and the midday summer Mediterranean sun) for skin types I and II on the Fitzpatrick scale. We use Monte Carlo Radiative Transfer (MCRT) modelling to track the progression of UV photons through a multi-layered three dimensional (3D) grid that simulates the upper layers of the skin...
May 12, 2018: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/29751729/unravelling-the-photoprotection-properties-of-mycosporine-amino-acid-motifs
#17
Jack Matthew Woolley, Michael Staniforth, Michael D Horbury, Gareth W Richings, Martin Wills, Vasilios G Stavros
Photoprotection from harmful ultraviolet (UV) radiation exposure is a key problem in modern society. Mycosporine like amino acids found in fungi, cyanobacteria, macroalgae, phytoplankton and humans, are already presenting a promising form of natural photoprotection in sunscreen formulations. Using time-resolved transient electronic absorption spectroscopy and guided by complementary ab initio calculations, we help to unravel how the core structures of these molecules perform under UV irradiation. Through such detailed insight into the relaxation mechanisms of these ubiquitous molecules, we hope to inspire new thinking in developing next generation sun protecting molecules...
May 11, 2018: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/29750411/effect-of-uv-b-irradiation-on-water-suspended-metarhizium-anisopliae-s-l-hypocreales-clavicipitaceae-conidia-and-their-larvicidal-activity-in-aedes-aegypti-diptera-culicidae
#18
Marianel L Falvo, Patricia Albornoz Medina, Juscelino Rodrigues, Claudia C López Lastra, Juan J García, Éverton K K Fernandes, Christian Luz
Ultraviolet (UV) radiation is a key limiting factor for biological pest control with entomopathogenic fungi. While little is known about the impact of UV on Metarhizium anisopliae Metchnikoff (Sorokin) (Hypocreales: Clavicipitaceae) conidia in aquatic mosquito-breeding sites, this study determined the effect of UV-B on the viability and virulence of M. anisopliae sensu lato (s.l.) strain IP 46 in the laboratory against Aedes aegypti (L.) (Diptera: Culicidae) larvae. Conidia were treated in cups under defined water depths (0, 1, 2, and 3 cm) to six different UV-B doses (0, 0...
May 10, 2018: Journal of Medical Entomology
https://www.readbyqxmd.com/read/29749727/in-situ-crystallization-synthesis-of-cspbbr3-perovskite-quantum-dots-embedded-glasses-with-improved-stability-for-solid-state-lighting-and-random-upconverted-lasing
#19
Shuo Yuan, Daqin Chen, Xinyue Li, Jiasong Zhong, Xuhui Xu
All-inorganic cesium lead bromide CsPbBr3 perovskite quantum dots (QDs) are emerging as potential candidates for the applications in optoelectronic devices but suffer from poor long-term stability due to their high sensitivity to UV irradiation, heat and especially to moisture. Although great advances in improving stability of perovskite QDs have been achieved by surface modification or encapsulation in polymer and silica, they are not sufficiently refrained from external environment due to non-dense structures of these protective layers...
May 11, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29748690/untargeted-lipidomic-analysis-of-primary-human-epidermal-melanocytes-acutely-and-chronically-exposed-to-uv-radiation
#20
Núria Dalmau, Nathalie Andrieu-Abadie, Romà Tauler, Carmen Bedia
Ultraviolet (UV) radiation present in sunlight has been related to harmful effects on skin such as premature aging and skin cancer. In order to study the effects of UV radiation on skin, many investigations have been carried out at transcriptomic and proteomic levels. However, studies on the effects of UV radiation on lipid composition are scarce. In this work, primary cultures of melanocytes were exposed to UV radiation in a similar UVA/UVB ratio to that found in solar light. The UV exposure was carried out twice a week and different endpoints were investigated at 0...
May 11, 2018: Molecular omics
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