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Penicillin susceptible staphylococcus

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https://www.readbyqxmd.com/read/28916003/genetic-diversity-and-antibiotic-susceptibility-of-staphylococcus-aureus-isolates-from-wild-boars
#1
D Seinige, A Von Altrock, C Kehrenberg
We here report the occurrence of S. aureus in wild boars and characterize isolates genotypically and phenotypically in order to get knowledge about the occurrence of clonal lineages and genotypes in free-living wild animals. Forty-one S. aureus isolates obtained from 111 wild boars hunted in Lower Saxony, Germany, were investigated and compared to human and livestock isolates. The S. aureus belonged to multilocus sequence types ST1, ST7, ST30, ST133, ST425, ST804, ST890 and to the new ST3237, ST3238, ST3255 and ST3369...
October 2017: Comparative Immunology, Microbiology and Infectious Diseases
https://www.readbyqxmd.com/read/28915926/antimicrobial-resistance-patterns-of-staphylococcus-species-isolated-from-cats-presented-at-a-veterinary-academic-hospital-in-south-africa
#2
Daniel Nenene Qekwana, Dikeledi Sebola, James Wabwire Oguttu, Agricola Odoi
BACKGROUND: Antimicrobial resistance is becoming increasingly important in both human and veterinary medicine. This study investigated the proportion of antimicrobial resistant samples and resistance patterns of Staphylococcus isolates from cats presented at a veterinary teaching hospital in South Africa. Records of 216 samples from cats that were submitted to the bacteriology laboratory of the University of Pretoria academic veterinary hospital between 2007 and 2012 were evaluated. Isolates were subjected to antimicrobial susceptibility testing against a panel of 15 drugs using the disc diffusion method...
September 15, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28900682/treatment-of-staphylococcus-aureus-infections
#3
Michael Z David, Robert S Daum
Staphylococcus aureus, although generally identified as a commensal, is also a common cause of human bacterial infections, including of the skin and other soft tissues, bones, bloodstream, and respiratory tract. The history of S. aureus treatment is marked by the development of resistance to each new class of antistaphylococcal antimicrobial drugs, including the penicillins, sulfonamides, tetracyclines, glycopeptides, and others, complicating therapy. S. aureus isolates identified in the 1960s were sometimes resistant to methicillin, a ß-lactam antimicrobial active initially against a majority S...
September 13, 2017: Current Topics in Microbiology and Immunology
https://www.readbyqxmd.com/read/28895381/penicillin-g-susceptibility-among-staphylococcus-aureus-is-not-so-infrequent-a-retrospective-study
#4
Josquin Moraly, Redouane Dahoumane, Vincent Dubée, Gabriel Préda, Jean-Luc Baudel, Jérémie Joffre, Naïke Bigé, Hafid Ait-Oufella, Eric Maury
No abstract text is available yet for this article.
September 11, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/28893360/borderline-oxacillin-resistant-staphylococcus-aureus-borsa-a-more-common-problem-than-expected
#5
Maria M Hryniewicz, Katarzyna Garbacz
Borderline oxacillin-resistant Staphylococcus aureus (BORSA) represents a quite poorly understood and inadequately defined phenotype of methicillin resistance. BORSA strains show low, borderline resistance to penicillinase-resistant penicillins (PRPs), with oxacillin MICs typically equal to 1-8 µg ml-1, and in contrast to methicillin-resistant S. aureus (MRSA), do not have an altered penicillin-binding protein, PBP2a, encoded by the mecA or mecC gene. Their resistance is typically associated with hyperproduction of beta-lactamases or, in some cases, point mutations in PBP genes...
September 12, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28866692/frequency-and-molecular-epidemiology-of-panton-valentine-leukocidin-gene-in-staphylococcus-aureus-colonising-hiv-infected-patients
#6
Z Mohd-Zain, S F A Mohd-Nawi, A Adnan, S Kumar
BACKGROUND: HIV-infected patients pose a high risk of contracting skin and soft tissue infections caused by Staphylococcus aureus. Those who are colonized with methicillin-resistant S. aureus (MRSA) that carry Panton-Valentine leukocidin (PVL) are predisposed to severe infections that could lead to necrotic skin infections. However the association of S. aureus specifically methicillin sensitive S. aureus carrying PVL gene in HIV patients has not been widely reported. Here, we study the prevalence and the molecular epidemiology of PVL-producing S...
August 2017: Malaysian Journal of Pathology
https://www.readbyqxmd.com/read/28865851/prevalence-antimicrobial-susceptibility-and-molecular-characterization-of-staphylococcus-aureus-isolated-from-dairy-herds-in-northern-china
#7
Huimin Liu, Songli Li, Lu Meng, Lei Dong, Shengguo Zhao, Xinyi Lan, Jiaqi Wang, Nan Zheng
Staphylococcus aureus is one of the main pathogens involved in dairy cow mastitis. Monitoring of antibiotic use would prove useful to assess the risk of Staph. aureus in raw milk. The objective of this work was to investigate the prevalence of Staph. aureus strains isolated from raw milk in northern China, and to characterize antimicrobial susceptibility of these strains and their key virulence genes. In total, 195 raw milk samples were collected from 195 dairy farms located in 4 cities of northern China from May to September 2015...
August 30, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28862669/antimicrobial-susceptibility-of-staphylococcus-aureus-isolated-from-recreational-waters-and-beach-sand-in-eastern-cape-province-of-south-africa
#8
Olufemi Emmanuel Akanbi, Henry Akum Njom, Justine Fri, Anthony C Otigbu, Anna M Clarke
Background: Resistance of Staphylococcus aureus to commonly used antibiotics is linked to their ability to acquire and disseminate antimicrobial-resistant determinants in nature, and the marine environment may serve as a reservoir for antibiotic-resistant bacteria. This study determined the antibiotic sensitivity profile of S.aureus isolated from selected beach water and intertidal beach sand in the Eastern Cape Province of South Africa. Methods: Two hundred and forty-nine beach sand and water samples were obtained from 10 beaches from April 2015 to April 2016...
September 1, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28830451/bacterial-pathogens-associated-with-external-ocular-infections-alongside-eminent-proportion-of-multidrug-resistant-isolates-at-the-university-of-gondar-hospital-northwest-ethiopia
#9
Ergibnesh Getahun, Baye Gelaw, Abate Assefa, Yared Assefa, Anteneh Amsalu
BACKGROUND: External ocular infection is a public health problem in Ethiopia. The aim of this study was to determine the prevalence and antimicrobial susceptibility pattern of external ocular bacterial infections. METHODS: A cross sectional study was conducted at the University of Gondar Hospital among patients seeking health services at the Department of Ophthalmology from January to April, 2016. All patients with suspected external ocular infections were examined under slit lamp microscope...
August 22, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28818544/trends-in-antimicrobial-resistance-in-bloodstream-infection-isolates-at-a-large-urban-hospital-in-malawi-1998-2016-a-surveillance-study
#10
Patrick Musicha, Jennifer E Cornick, Naor Bar-Zeev, Neil French, Clemens Masesa, Brigitte Denis, Neil Kennedy, Jane Mallewa, Melita A Gordon, Chisomo L Msefula, Robert S Heyderman, Dean B Everett, Nicholas A Feasey
BACKGROUND: Bacterial bloodstream infection is a common cause of morbidity and mortality in sub-Saharan Africa, yet few facilities are able to maintain long-term surveillance. The Malawi-Liverpool-Wellcome Trust Clinical Research Programme has done sentinel surveillance of bacteraemia since 1998. We report long-term trends in bloodstream infection and antimicrobial resistance from this surveillance. METHODS: In this surveillance study, we analysed blood cultures that were routinely taken from adult and paediatric patients with fever or suspicion of sepsis admitted to Queen Elizabeth Central Hospital, Blantyre, Malawi from 1998 to 2016...
August 14, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28789605/analysis-of-distribution-and-antibiotic-resistance-of-pathogens-isolated-from-the-paediatric-population-in-shenmu-hospital-from-2011-2015
#11
Yang Hui-Min, Wang Yan-Ping, Yong Lin Liu, Bilal Haider Shamsi, He Bo, Meng Xu-Chun
Objective This study aimed to investigate the epidemiology and changes in antibacterial susceptibility of children in Shenmu City, northern Shaanxi, and provide a basis for rational drug use. Methods The distribution and drug resistance pattern of pathogenic bacteria isolated from children were retrospectively analysed. Results A total of 573 strains of pathogens were cultivated. A total of 201 (35.07%) strains of Gram-positive cocci and 183 (31.93%) strains of Gram-negative cocci were detected. A total of 189 (32...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28771160/staphylococcus-aureus-isolated-from-wastewater-treatment-plants-in-tunisia-occurrence-of-human-and-animal-associated-lineages
#12
Meriam Ben Said, Mohamed Salah Abbassi, Paula Gómez, Laura Ruiz-Ripa, Senda Sghaier, Chourouk Ibrahim, Carmen Torres, Abdennaceur Hassen
The objective was to characterize Staphylococcus aureus isolated from two wastewater treatment plants (WWTPs) located in Tunis City (Tunisia), during the period 2014-2015. Genetic lineages, antibiotic resistance mechanisms and virulence factors were determined for the recovered isolates. S. aureus isolates were recovered from 12 of the 62 wastewater samples tested (19.35%), and one isolate/sample was characterized, all of them being methicillin-susceptible (MSSA). Six spa types (t587, t674, t224, t127, t701 and t1534) were found among the 12 isolates, and the spa-t587, associated with the new sequence type ST3245, was the most predominant one (7 isolates)...
August 2017: Journal of Water and Health
https://www.readbyqxmd.com/read/28754460/virulence-and-antibiotic-resistance-of-staphylococcus-aureus-isolated-from-bloodstream-infections-and-pneumonia-in-southern-poland
#13
Monika Pomorska-Wesołowska, Agnieszka Chmielarczyk, Monika Chlebowicz, Grzegorz Ziółkowski, Anna Szczypta, Joanna Natkaniec, Dorota Romaniszyn, Monika Pobiega, Mirosława Dzikowska, Lech Krawczyk, Joanna Kozioł, Jadwiga Wójkowska-Mach
OBJECTIVES: Staphylococcus aureus remains the most important cause of infections in hospitals and long-term care facilities.The aim of this study was to analyse the resistance, virulence and the epidemiological and genetic relationship of SA from bloodstream infections and pneumonia from patients in Southern Poland. METHODS: All strains were tested using disk diffusion antimicrobial susceptibility methods. E-tests for vancomycin, teicoplanin, tygecycline, oxacillin, cefoxitin and penicillin were also performed...
July 25, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28742382/occurrence-and-antibiotic-susceptibility-of-listeria-species-and-staphylococcus-aureus-in-cattle-slaughterhouses-of-kerala-south-india
#14
Tanuja K G M Gowda, Latha C, Sunil B, Inge Van Damme
A total of 765 samples were collected from beef carcasses, knives, cutting table surfaces, beef, hands, air, and water from four cattle slaughterhouses of Kerala, South India, to determine the occurrence and antibiotic susceptibility of Listeria species and Staphylococcus aureus. Listeria spp. were isolated from beef carcasses (2.0%), knives (3.7%), cutting table surfaces (1.9%), beef (0.7%), and water (1.3%). The identified species were Listeria monocytogenes (0.1%), Listeria innocua (0.9%), and Listeria ivanovii (0...
July 25, 2017: Foodborne Pathogens and Disease
https://www.readbyqxmd.com/read/28735054/linezolid-activity-against-clinical-gram-positive-cocci-with-advanced-antimicrobial-drug-resistance-in-iran
#15
Hamidreza Houri, Hossein Kazemian, Hadi Sedigh Ebrahim-Saraie, Asieh Taji, Zahra Tayebi, Hamid Heidari
OBJECTIVES: The aim of the study was to investigate the linezolid activity against clinical Gram-positive cocci with advanced antimicrobial drug resistance. METHODS: A collection of methicillin resistant Staphylococcus aureus (MRSA), vancomycin resistant enterococci (VRE), penicillin non-susceptible Streptococcus pneumoniae (PNSP), and group B streptococci (GBS) were isolated from various clinical samples. Antimicrobial susceptibility tests were done using standard methods Subsequently, we investigated linezolid antibacterial activities, the first approved oxazolidinone against isolates by the standard broth microdilution method...
September 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28735053/activity-of-dalbavancin-tested-against-gram-positive-clinical-isolates-causing-skin-and-skin-structure-infections-in-paediatric-patients-from-us-hospitals-2014-2015
#16
Michael A Pfaller, Rodrigo E Mendes, Helio S Sader, Mariana Castanheira, Robert K Flamm
OBJECTIVES: This study provides an in vitro analysis of dalbavancin activity against isolates causing skin and skin-structure infections (SSSIs) in children. METHODS: A total of 770 Staphylococcus aureus, 167 β-haemolytic streptococci (BHS), 42 coagulase-negative staphylococci (CoNS), 25 Enterococcus faecalis and 13 viridans group streptococci (VGS) were collected from children (<18years old) in the USA (2014-2015). RESULTS: Dalbavancin had MIC50/90 values of 0...
July 19, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28733674/role-of-sccmec-type-in-resistance-to-the-synergistic-activity-of-oxacillin-and-cefoxitin-in-mrsa
#17
Nathalie T Reichmann, Mariana G Pinho
β-lactam antibiotics target penicillin-binding proteins (PBPs) preventing peptidoglycan synthesis and this inhibition is circumvented in methicillin resistant Staphylococcus aureus (MRSA) strains through the expression of an additional PBP, named PBP2A. This enzyme is encoded by the mecA gene located within the Staphylococcal Chromosome Cassette mec (SCCmec) mobile genetic element, of which there are 12 types described to date. Previous investigations aimed at analysing the synergistic activity of two β-lactams, oxacillin and cefoxitin, found that SCCmec type IV community-acquired MRSA strains exhibited increased susceptibility to oxacillin in the presence of cefoxitin, while hospital-acquired MRSA strains were unaffected...
July 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28732791/detection-of-a-mecc-positive-staphylococcus-saprophyticus-from-bovine-mastitis-in-argentina
#18
Mariela E Srednik, Marie Archambault, Mario Jacques, Elida R Gentilini
INTRODUCTION: Bovine mastitis causes important economic losses in the dairy industry. Coagulase-negative staphylococci (CNS) are a group of bacteria commonly isolated from bovine mastitis and can display resistance to a wide range of antimicrobial agents. OBJECTIVES: The objective of this study was to determine staphylococcal resistance towards β-lactam, macrolide and lincosamide antimicrobials in quarters previously treated with third-generation cephalosporin and after lincosamide intramammary therapy...
September 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28729209/clonal-spread-of-methicillin-resistant-staphylococcus-aureus-t6065-cc5-sccmecv-agrii-in-a-libyan-hospital
#19
Monia Khemiri, Ali Akrout Alhusain, Mohamed Salah Abbassi, Houyem El Ghaieb, Sofia Santos Costa, Adriana Belas, Constança Pomba, Salah Hammami
OBJECTIVES: The aim of this study was to characterize 32 MRSA isolates recovered from wound specimens of patients in a Hospital in Tripoli, Libya, during 2013. METHODS: MRSA isolates were characterized by determining their antibiotic susceptibilities, genes encoding antibiotic resistance and virulence factors, the SCCmec class, agr type, spa typing, PFGE and MLST. RESULTS: PFGE and MLST revealed that all isolates were clonal and belonged to the Clonal Complex 5 (CC5)...
September 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28722566/molecular-epidemiology-of-staphylococcus-aureus-skin-and-soft-tissue-infections-in-the-lao-people-s-democratic-republic
#20
Alicia D Yeap, Kate Woods, David A B Dance, Bruno Pichon, Sayaphet Rattanavong, Viengmon Davong, Rattanaphone Phetsouvanh, Paul N Newton, Nandini Shetty, Angela M Kearns
This is the first report of the molecular epidemiology of Staphylococcus aureus from skin and soft tissue infections (SSTI) in Laos. We selected a random sample of 96 S. aureus SSTI isolates received by the Microbiology Laboratory, Mahosot Hospital, Vientiane, between July 2012 and June 2014, including representation from seven referral hospitals. Isolates underwent susceptibility testing by Clinical and Laboratory Standards Institute methods, spa typing and DNA microarray analysis, with whole genome sequencing for rare lineages...
August 2017: American Journal of Tropical Medicine and Hygiene
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