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https://www.readbyqxmd.com/read/27722223/immediate-early-6-weeks-and-delayed-loading-3%C3%A2-months-of-single-implants-4-month-%C3%A2-post-loading-from-a-multicenter-pragmatic-randomised-controlled-trial
#1
Marco Esposito, Konstantinos Siormpas, Miltiadis Mitsias, Soheil Bechara, Anna Trullenque-Eriksson, Roberto Pistilli
PURPOSE: To compare the clinical outcome of single, partial and full fixed implant-supported prostheses immediately loaded (within 48 h), early loaded at 6 weeks and conventionally loaded at 3 months (delayed loading). MATERIALS AND METHODS: Eighty-one patients (27 requiring single implants, 27 requiring partial fixed prostheses and 27 requiring total fixed cross-arch prostheses) were randomised in equal numbers in three private practices to immediate loading (27 patients), early loading (27 patients) and conventional loading (27 patients) according to a parallel group design with three arms...
2016: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/27699890/the-effect-of-implant-macro-thread-design-on-implant-stability-in-the-early-post-operative-period-a-randomized-controlled-pilot-study
#2
Jeffrey J McCullough, Perry R Klokkevold
INTRODUCTION: Available literature suggests there is a transient drop in implant stability from approximately week 0 to week 3-4 as a result of peri-implant bone remodeling as it transitions from a primary, mechanical stability to a secondary, biological stability. Research investigating the influence of macro-thread design on this process is scant. AIM: The specific aim of this study was to evaluate the role of macro-thread design on implant stability in the early post-operative healing period using resonance frequency analysis (RFA)...
October 3, 2016: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/27492985/accuracy-of-torque-limiting-devices-a-comparative-evaluation
#3
Haydar Albayrak, Hasan Onder Gumus, Funda Tursun, Hasan Huseyin Kocaagaoglu, Halil Ibrahim Kilinc
STATEMENT OF PROBLEM: To prevent the loosening of implant screws, clinicians should be aware of the output torque values needed to achieve the desired preload. Accurate torque-control devices are crucial in this regard; however, little information is currently available comparing the accuracy of mechanical with that of electronic torque-control devices. PURPOSE: The purpose of this in vitro study was to identify and compare the accuracy of different types of torque-control devices...
August 1, 2016: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/27433693/histological-evaluation-of-nano-micro-titanium-implant-surface-treatment-in-beagle-humerus
#4
Kwidug Yun, Seongsoo Kang, Gyejeong Oh, Hyunpil Lim, Kwangmin Lee, Hongso Yang, Mongsook Vang, Sangwon Park
The objective of this study was to investigate the effects of nano-micro titanium implant surface using histology in beagle dogs. A total of 48 screw-shaped implants (Megagen, Daegu, Korea) which dimensions were 4 mm in diameter and 8.5 mm in length, were used. The implants were classified into 4 groups (n = 12): machined surface (M group), RBM (Resorbable Blasting Media) surface (R group), nano surface which is nanotube formation on the machined surface (MA group) and nano-micro surface which is nanotube formation on the RBM surface (RA group)...
February 2016: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/27402427/short-6-mm-dental-implants-versus-sinus-floor-elevation-and-placement-of-longer-%C3%A2-10-mm-dental-implants-a-randomized-controlled-trial-with-a-3-year-follow-up
#5
Souheil Bechara, Ricardas Kubilius, Giovanni Veronesi, Jefferson T Pires, Jamil A Shibli, Francesco G Mangano
OBJECTIVES: To investigate whether short (6-mm) dental implants could be an alternative to sinus floor elevation (SFE) and placement of longer (≥10-mm) implants in the posterior maxilla. MATERIALS AND METHODS: Over a 3-year period, all patients presenting with partial edentulism in the posterior maxilla were considered for inclusion in this randomized controlled trial. Patients were randomly chosen either to receive short (6-mm) implants (test group [TG]) or to undergo SFE with simultaneous placement of standard-length (≥10-mm) implants (control group [CG])...
July 12, 2016: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/27314118/dental-implants-with-internal-versus-external-connections-5-year-post-loading-results-from-a-pragmatic-multicenter-randomised-controlled-trial
#6
Marco Esposito, Hassan Maghaireh, Roberto Pistilli, Maria Gabriella Grusovin, Sang Taek Lee, Anna Trullenque-Eriksson, Federico Gualini
PURPOSE: To evaluate advantages and disadvantages of identical implants with internal or external connections. MATERIALS AND METHODS: One hundred and twenty patients with any type of edentulism (single tooth, partial and total edentulism), requiring one implant-supported prosthesis were randomly allocated in two equal groups to receive either implants with an external connection (EC) or implants of the same type with an internal connection (IC) (EZ Plus, MegaGen Implant, Gyeongbuk, South Korea), at four centres...
2016: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/27298621/soft-tissue-stability-around-single-implants-inserted-to-replace-maxillary-lateral-incisors-a-3d-evaluation
#7
F G Mangano, F Luongo, G Picciocchi, C Mortellaro, K B Park, C Mangano
Purpose. To evaluate the soft tissue stability around single implants inserted to replace maxillary lateral incisors, using an innovative 3D method. Methods. We have used reverse-engineering software for the superimposition of 3D surface models of the dentogingival structures, obtained from intraoral scans of the same patients taken at the delivery of the final crown (S1) and 2 years later (S2). The assessment of soft tissues changes was performed via calculation of the Euclidean surface distances between the 3D models, after the superimposition of S2 on S1; colour maps were used for quantification of changes...
2016: International Journal of Dentistry
https://www.readbyqxmd.com/read/26669544/dental-implants-with-internal-versus-external-connections-1-year-post-loading-results-from-a-pragmatic-multicenter-randomised-controlled-trial
#8
RANDOMIZED CONTROLLED TRIAL
Marco Esposito, Hassan Maghaireh, Roberto Pistilli, Maria Gabriella Grusovin, Sang Taek Lee, Federico Gualini, Jungtaek Yoo, Jacopo Buti
PURPOSE: To evaluate advantages and disadvantages of identical implants with internal or external connections. MATERIALS AND METHODS: Two hundred patients with any type of edentulism (single tooth, partial and total edentulism) requiring one implant-supported prosthesis were randomly allocated in two equal groups to receive either implants with an external connection (EC) or implants of the same type but with an internal connection (IC) (EZ Plus, MegaGen Implant, Gyeongbuk, South Korea) at seven centres...
2015: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/26436099/anodisation-increases-integration-of-unloaded-titanium-implants-in-sheep-mandible
#9
Warwick J Duncan, Min-Ho Lee, Tae-Sung Bae, Sook-Jeong Lee, Jennifer Gay, Carolina Loch
Spark discharge anodic oxidation forms porous TiO2 films on titanium implant surfaces. This increases surface roughness and concentration of calcium and phosphate ions and may enhance early osseointegration. To test this, forty 3.75 mm × 13 mm titanium implants (Megagen, Korea) were placed into healed mandibular postextraction ridges of 10 sheep. There were 10 implants per group: RBM surface (control), RBM + anodised, RBM + anodised + fluoride, and titanium alloy + anodised surface. Resonant frequency analysis (RFA) was measured in implant stability quotient (ISQ) at surgery and at sacrifice after 1-month unloaded healing...
2015: BioMed Research International
https://www.readbyqxmd.com/read/26355169/safety-and-effectiveness-of-early-loaded-maxillary-titanium-implants-with-a-novel-nanostructured-calcium-incorporated-surface-xpeed-3-year-results-from-a-pilot-multicenter-randomised-controlled-trial
#10
RANDOMIZED CONTROLLED TRIAL
Pietro Felice, Maria Gabriella Grusovin, Carlo Barausse, Giovanni Grandi, Marco Esposito
PURPOSE: To evaluate clinical safety and effectiveness of a novel calcium-incorporated titanium implant surface (Xpeed, MegaGen Implant Co., Gyeongbuk, South Korea). MATERIALS AND METHODS: Sixty patients were randomised to receive one to six implants in the maxilla with either calcium-incorporated (Xpeed) or control resorbable blasted media (RBM) surfaces, according to a parallel group design at two centres. Implants were submerged and exposed at three different endpoints in equal groups of 20 patients, each at 12, 10 and 8 weeks, respectively...
2015: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/26331059/effect-of-osteoconductive-hyaluronate-hydrogels-on-calvarial-bone-regeneration
#11
Junseok Yeom, Byung Woo Hwang, Dong Jun Yang, Hong-In Shin, Sei Kwang Hahn
BACKGROUND: Without exploitation of possibly immunogenic and carcinogenic bone morphogenetic protein, we developed simple but clinically feasible artificial bone graft using osteoconductive hyaluronate (HA) hydrogels and bioactive MegaGen synthetic bone (MGSB). METHODS: HA hydrogels were synthesized by the crosslinking reaction between carboxyl groups of HA and amine groups of gelatin (GEL). Then, artificial bone grafts were prepared by mixing MGSB with HA-GEL hydrogels...
2014: Biomaterials Research
https://www.readbyqxmd.com/read/26064701/custom-made-computer-aided-design-computer-aided-manufacturing-biphasic-calcium-phosphate-scaffold-for-augmentation-of-an-atrophic-mandibular-anterior-ridge
#12
Francesco Guido Mangano, Piero Antonio Zecca, Ric van Noort, Samvel Apresyan, Giovanna Iezzi, Adriano Piattelli, Aldo Macchi, Carlo Mangano
This report documents the clinical, radiographic, and histologic outcome of a custom-made computer-aided-design/computer-aided-manufactured (CAD/CAM) scaffold used for the alveolar ridge augmentation of a severely atrophic anterior mandible. Computed tomographic (CT) images of an atrophic anterior mandible were acquired and modified into a 3-dimensional (3D) reconstruction model; this was transferred to a CAD program, where a custom-made scaffold was designed. CAM software generated a set of tool-paths for the manufacture of the scaffold on a computer-numerical-control milling machine into the exact shape of the 3D design...
2015: Case Reports in Dentistry
https://www.readbyqxmd.com/read/24977254/immediate-functional-loading-of-single-implants-a-1-year-interim-report-of-a-5-year-prospective-multicentre-study
#13
MULTICENTER STUDY
Giuseppe Luongo, Carolina Lenzi, Filiep Raes, Tammaro Eccellente, Michele Ortolani, Carlo Mangano
PURPOSE: The aim of this prospective multicentre study was to evaluate the clinical outcome of immediately loaded single implants. MATERIALS AND METHODS: Patients were recruited at six clinical centres. Inclusion criteria were singletooth replacement in fully healed sites or post-extraction sockets with adequate bone height and width, to place an implant of at least 3.5 mm in diameter and 10.0 mm in length. All implants (AnyRidge, MegaGen, Gyeongbuk, South Korea) were functionally loaded immediately after placement...
2014: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/24570980/posterior-atrophic-jaws-rehabilitated-with-prostheses-supported-by-5-x-5-mm-implants-with-a-novel-nanostructured-calcium-incorporated-titanium-surface-or-by-longer-implants-in-augmented-bone-one-year-results-from-a-randomised-controlled-trial
#14
RANDOMIZED CONTROLLED TRIAL
Roberto Pistilli, Pietro Felice, Maurizio Piattelli, Manlio Gessaroli, Elisa Soardi, Carlo Barausse, Jacopo Buti, Valeria Corvino
PURPOSE: To evaluate whether 5 × 5 mm dental implants with a novel nanostructured calciumincorporated titanium surface could be an alternative to implants at least 10 mm long placed in bone augmented with bone substitutes in posterior atrophic jaws. MATERIALS AND METHODS: A total of 40 patients with atrophic posterior (premolar and molar areas) mandibles having 5 to 7 mm of bone height above the mandibular canal and 40 patients with atrophic maxillae having 4 to 6 mm below the maxillary sinus, were randomised according to a parallel group design to receive one to three 5 mm implants or one to three at least 10 mm-long implants in augmented bone at two centres...
2013: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/24159795/-125th-birth-anniversary-of-the-outstanding-botanist-peter-mikhailovich-zhukovsky
#15
N P Goncharov
Peter Mikhailovich Zhykovsky--botanist, monograph of the genus Aegilops, closest associate of N.N. Vavilov, Director of the All-Union Institute of Plant Industry, Academic Secretary of the Department of Agriculture of VASKhNIL, and the first Editor-in-Chief of the Genetika journal. He postulated a theory on host-parasite coevolution at their common place of origin, and put forward the concept on Megagene centers of origin of cultivated plants and their endemic Microgene centers. He discovered and described the new wheat species Triticum timopheevii (Zhuk...
May 2013: Genetika
https://www.readbyqxmd.com/read/23000708/safety-and-effectiveness-of-maxillary-early-loaded-titanium-implants-with-a-novel-nanostructured-calcium-incorporated-surface-xpeed-1-year-results-from-a-pilot-multicenter-randomised-controlled-trial
#16
RANDOMIZED CONTROLLED TRIAL
Marco Esposito, Maria Gabriella Grusovin, Gerardo Pellegrino, Elisa Soardi, Pietro Felice
PURPOSE: To evaluate clinical safety and effectiveness of a novel calcium-incorporated titanium implant (Xpeed, MegaGen Implant Co. Limited, Gyeongbuk, South Korea). MATERIALS AND METHODS: Sixty patients were randomised to receive either 1 to 6 calcium-incorporated or control titanium implants in the maxilla according to a parallel group design at 2 different centres. Implants were submerged and exposed at 3 different endpoints in equal groups of 20 patients each at 12, 10 and 8 weeks, respectively...
2012: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/20467603/bone-augmentation-versus-5-mm-dental-implants-in-posterior-atrophic-jaws-four-month-post-loading-results-from-a-randomised-controlled-clinical-trial
#17
RANDOMIZED CONTROLLED TRIAL
Pietro Felice, Vittorio Checchi, Roberto Pistilli, Antonio Scarano, Gerardo Pellegrino, Marco Esposito
PURPOSE: To evaluate whether short (5 mm) dental implants could be a suitable alternative to augmentation and placement of longer implants (10 mm) in posterior atrophic jaws. MATERIALS AND METHODS: Thirty partially edentulous patients with bilateral posterior edentulism were included: 15 patients having 5 to 7 mm of residual crestal height above the mandibular canal, and 15 patients having 4 to 6 mm of residual crestal height below the maxillary sinus and bone thickness of at least 8 mm measured on a CT scan...
2009: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/20073984/synchrotron-x-ray-bioimaging-of-bone-regeneration-by-artificial-bone-substitute-of-megagen-synthetic-bone-and-hyaluronate-hydrogels
#18
Junseok Yeom, Soeun Chang, Jung Kyu Park, Jung Ho Je, Dong Jun Yang, Seok Kyu Choi, Hong-In Shin, Seung-Jae Lee, Jin-Hyung Shim, Dong-Woo Cho, Sei Kwang Hahn
Synchrotron X-ray bioimaging was successfully carried out to observe bone regeneration by a novel artificial bone substitute of bioactive MegaGen Synthetic Bone (MGSB) and hyaluronate (HA) hydrogels. A biphasic calcium phosphate of MGSB was prepared by chemical precipitation method, with a porous spherical morphology. On the basis of the fact that HA plays important roles in bone regeneration and promotes the differentiation, vascularization, and migration of stem cells, HA-cystamine (CYS) hydrogels with cleavable disulfide linkages were prepared to supply HA continuously for effective bone regeneration by their controlled degradation in vivo...
October 2010: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/16583938/-neurofibromatosis-type-1-von-recklinghausen-s-disease-or-peripheral-neurofibromatosis-from-phenotype-to-gene
#19
REVIEW
Zlatko Sabol, Ljiljana Kipke-Sabol
Neurofibromatosis type 1 (NF1) is an autosomal dominant disease with a prevalence of about 1/3000. The clinical diagnosis of NF1 is based on the presence of two or more of the following criteria: six or more café au lait spots, >2 neurofibromas of any type or 1 plexiform neurofibroma, freckling in the axillary or inguinal region, optic glioma, a distinctive osseous lesion such as sphenoid dysplasia or thinning of long bone cortex with or without pseudoarthrosis, and a first degree relative with NF1. The disease has numerous complications...
November 2005: Lijec̆nic̆ki Vjesnik
https://www.readbyqxmd.com/read/15554972/positive-control-of-tylosin-biosynthesis-pivotal-role-of-tylr
#20
George Stratigopoulos, Neil Bate, Eric Cundliffe
Control of tylosin production in Streptomyces fradiae features interplay between a repressor, TylQ, and an activator, TylS, during regulation of tylR. The latter encodes a pathway-specific activator that controls most of the tylosin-biosynthetic (tyl) genes that are subject to regulation. This was established by targeted gene disruption applied separately to tylR and tylS together with transcript analysis involving reverse transcription polymerase chain reaction (RT-PCR). TylR controls multiple genes that encode the synthesis or addition of all three tylosin sugars, plus polyketide ring oxidation, and at least one of the polyketide synthase (PKS) megagenes, tylGI...
December 2004: Molecular Microbiology
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